针对触摸屏监控系统不能满足大中型立体仓库对数据进行存储和处理的功能需求,在Visual Studio 2019集成开发环境中,采用C#语言开发一套立体仓库上位机控制系统。以多线程的方式实时读取库位信息;以S7-1200 PLC作为主控制器,设计产品的...针对触摸屏监控系统不能满足大中型立体仓库对数据进行存储和处理的功能需求,在Visual Studio 2019集成开发环境中,采用C#语言开发一套立体仓库上位机控制系统。以多线程的方式实时读取库位信息;以S7-1200 PLC作为主控制器,设计产品的自动入库和自动出库程序流程,采用SCL语言设计了库位先进先出的控制程序。C#和S7-1200 PLC之间采用S7通信的方式控制立体仓库的出入库操作和库位信息采集,3年的现场运行情况表明,整个系统能在上位机上对立体仓库进行手动控制和自动控制,能精确快速地进行入库出库操作,运行平稳,上位机上能正确实时显示库位信息,达到了预期的结果。展开更多
Synaptic plasticity is essential for maintaining neuronal function in the central nervous system and serves as a critical indicator of the effects of neurodegenerative disease.Glaucoma directly impairs retinal ganglio...Synaptic plasticity is essential for maintaining neuronal function in the central nervous system and serves as a critical indicator of the effects of neurodegenerative disease.Glaucoma directly impairs retinal ganglion cells and their axons,leading to axonal transport dysfuntion,subsequently causing secondary damage to anterior or posterior ends of the visual system.Accordingly,recent evidence indicates that glaucoma is a degenerative disease of the central nervous system that causes damage throughout the visual pathway.However,the effects of glaucoma on synaptic plasticity in the primary visual cortex remain unclear.In this study,we established a mouse model of unilateral chronic ocular hypertension by injecting magnetic microbeads into the anterior chamber of one eye.We found that,after 4 weeks of chronic ocular hypertension,the neuronal somas were smaller in the superior colliculus and lateral geniculate body regions of the brain contralateral to the affected eye.This was accompanied by glial cell activation and increased expression of inflammatory factors.After 8 weeks of ocular hypertension,we observed a reduction in the number of excitatory and inhibitory synapses,dendritic spines,and activation of glial cells in the primary visual cortex contralateral to the affected eye.These findings suggest that glaucoma not only directly damages the retina but also induces alterations in synapses and dendritic spines in the primary visual cortex,providing new insights into the pathogenesis of glaucoma.展开更多
AIM:To compare the visual outcomes between bilateral implantation of Tecnis ZXR00 extended depth-of-focus(EDOF)intraocular lenses(IOLs)and mixed implantation of Tecnis ZXR00(EDOF)with Tecnis ZMB00(bifocal)IOLs.METHODS...AIM:To compare the visual outcomes between bilateral implantation of Tecnis ZXR00 extended depth-of-focus(EDOF)intraocular lenses(IOLs)and mixed implantation of Tecnis ZXR00(EDOF)with Tecnis ZMB00(bifocal)IOLs.METHODS:This postoperative cross-sectional study enrolled patients who underwent phacoemulsification combined with IOL implantation.Patients were divided into two groups:the bilateral ZXR00 group(ZXR00-only group)and the mixed IOL group(ZXR00+ZMB00 group).Primary outcome measures included uncorrected and corrected distance visual acuity(UDVA,CDVA),uncorrected and distance-corrected near visual acuity(UNVA,DCNVA),uncorrected and distance-corrected intermediate visual acuity(UIVA,DCIVA),and defocus curves.Secondary outcome measures were visual quality,spectacle independence,patient satisfaction,photic phenomena,and stereopsis.RESULTS:A total of 47 patients(94 eyes)were included,with 26 patients(11 males,15 females)in the ZXR00-only group(mean age:62.73±7.24y)and 21 patients(7 males,14 females)in the mixed group(mean age:65.71±9.16y).There was no statistically significant difference in age between the two groups(P=0.218).The mixed group showed significantly better binocular DCNVA compared to the ZXR00-only group(P=0.002).Defocus curve analysis revealed that the mixed group exhibited superior performance at−2.5 to−4.0 D but inferior performance at−0.5 and−1.5 D.Near stereoacuity was significantly poorer in the mixed group(Randot:5.589±0.744 vs 6.240±0.394 ln arcsec;Contour:4.966±0.973 vs 5.740±0.833 ln arcsec;both P<0.01).Both groups achieved high levels of spectacle independence and patient satisfaction,with no significant differences in photic phenomena or questionnaire scores.CONCLUSION:Mixed implantation of EDOF and bifocal IOLs improve near visual acuity but may compromise near stereopsis.This approach provides a viable option for patients prioritizing near vision;however,caution is recommended for individuals requiring fine stereoscopic vision for daily or professional tasks.展开更多
Dear Editor,This letter addresses the formation control problem for unmanned surface vehicles(USVs)under GPS-denied environments.A novel visual servo formation control scheme,utilizing a monocular camera on the follow...Dear Editor,This letter addresses the formation control problem for unmanned surface vehicles(USVs)under GPS-denied environments.A novel visual servo formation control scheme,utilizing a monocular camera on the follower to obtain the leader’s global position,is developed,which is also capable of guaranteeing collision avoidance and visibility maintenance(CA&VM)raised by the requirement of actual formation navigation.展开更多
Neuromorphic visual perception,by emulating the efficient information processing mechanisms of biological vision systems and integrating innovations in materials and device architectures,offers novel solutions for art...Neuromorphic visual perception,by emulating the efficient information processing mechanisms of biological vision systems and integrating innovations in materials and device architectures,offers novel solutions for artificial intelligence sensing.For instance,the incorporation of low-dimensional materials(e.g.,quantum dots,carbon nanotubes,and two-dimensional materials)optimizes device optoelectronic properties,while the synergistic design of organic semiconductors and oxide materials balances flexibility with complementary metal-oxide-semiconductor(CMOS)compatibility.Representative neuromorphic devices such as memristors and neuromorphic transistors address traditional vision system bottlenecks via near-sensor and in-sensor architectures in data transmission latency and energy consumption,offering a new paradigm for highly integrated,energy-efficient real-time perception.However,critical challenges—including device non-uniformity caused by material interface defects,system instability induced by memristor conductance drift,and environmental adaptability under complex illumination—remain barriers to scalable applications.This review comprehensively examines neuromorphic visual perception devices from the perspectives of device structure,operational mechanisms,materials,and applications.It explores the pivotal roles of memristors,electrolyte-gated transistors,and other neuromorphic devices in optical signal perception and information processing,with a focus on their implementations in visual perception tasks and future prospects.展开更多
While degenerative diseases of the central nervous system are commonly linked to age-related macular degeneration and glaucoma,they have also been infrequently associated with retinitis pigmentosa,a condition defined ...While degenerative diseases of the central nervous system are commonly linked to age-related macular degeneration and glaucoma,they have also been infrequently associated with retinitis pigmentosa,a condition defined by retinal degeneration that can be caused by an isoform of receptor expression enhancing protein 6(REEP6)expressed in rod photoreceptors.In this study,we used REEP6 knockout mice(REEP6^(-/-))and wild-type mice(REEP6^(+/+))to examine neurodegenerative pathology within the visual pathways and neural activity in the primary visual cortex(V1)at three specific time points(1,6,and 10 months)during retinitis pigmentosa progression.Microglial activation was observed in both the retina and the primary visual cortex starting at 1 month of age,but no such activation was detected in the lateral geniculate nucleus at any time point.Not only was increased microglial activation observed at 6 and 10 months within the primary visual cortex of REEP6^(-/-)mice,but also coinciding with elevated levels of phosphorylated Tau expression.At 6 and 10 months of age,primary visual cortex neurons in REEP6^(-/-)mice exhibited reduced responses to grating stimuli and increased spontaneous activity compared with neurons in the primary visual cortex of mice in the control group.Our findings show that retinitis pigmentosa induces neurodegenerative pathology within the visual pathway of mice,particularly in the primary visual cortex,suggesting that ocular disease contributes substantially to central nervous system degeneration.It may provide new clues for the selection of treatment opportunities and the development of therapeutic measures for the subsequent treatment of retinitis pigmentosa or even other retinal degenerative diseases.展开更多
This study extends the self-propelled particle(SPP)model by incorporating a limited vision cone and local density sensing.The results reveal that clusters can simultaneously exhibit velocity polarization and spatial c...This study extends the self-propelled particle(SPP)model by incorporating a limited vision cone and local density sensing.The results reveal that clusters can simultaneously exhibit velocity polarization and spatial cohesion within specific ranges of vision angle and density threshold.The dependence of the dynamical features,including the order parameter and density variation,on the threshold and visual cone is investigated.Furthermore,a critical threshold is identified,which governs the transition between ordered and disordered states and is closely linked to density fluctuations and noise intensity.The clustering results show that the model is explained by the chasing mechanism responsible for cluster formation,density,and shape.These results may stimulate practical applications in swarm maneuvering.展开更多
AIM:To identify early biomarkers associated with glaucomatous visual field(VF)progression in patients with normal-tension glaucoma(NTG).METHODS:This study included patients were divided into two groups based on diseas...AIM:To identify early biomarkers associated with glaucomatous visual field(VF)progression in patients with normal-tension glaucoma(NTG).METHODS:This study included patients were divided into two groups based on disease progression status.Tear samples were collected for proteomic analysis.Dataindependent acquisition(DIA)mass spectrometry combined with bioinformatic analyses was performed to identify and validate potential protein biomarkers for NTG progression.Additionally,differentially expressed proteins(DEPs)were evaluated using mediating effect models and receiver operating characteristic(ROC)curve analysis.RESULTS:A total of 19 patients(20 eyes)with NTG participated in this study,including 10 patients(4 males and 6 females;10 eyes)in the progression group with mean age of 67.70±9.03y and 10 patients(4 males and 6 females;10 eyes)in the non-progression group with mean age of 68.60±7.58y.A total of 158 significantly differentially expressed proteins were detected.UniProt database annotation identified 3 upregulated proteins and 12 downregulated proteins.Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway analysis showed that these DEPs were mainly enriched in pathways such as oocyte meiosis.Gene Ontology(GO)enrichment analysis revealed functional clusters related to cellular processes.Weighted gene coexpression network analysis(WGCNA)indicated that the core proteins were primarily involved in the neurodegenerationmultiple diseases pathway and cellular processes.Mediating effect analysis identified PRDX4(L)as a potential protein biomarker.ROC curve analysis showed that GNAI1 had the largest area under the curve(AUC=0.889).CONCLUSION:This study identifies 15 differentially expressed proteins in the tear fluid of NTG patients,including PRDX4(L).PRDX4(L)plays a key role in oxidative stress.展开更多
Urban green spaces have positive effects on both physical and mental wellbeing.However,few studies have focused on the trends and thresholds of the effects of different influences on restorative benefits when viewing ...Urban green spaces have positive effects on both physical and mental wellbeing.However,few studies have focused on the trends and thresholds of the effects of different influences on restorative benefits when viewing scenes differfeaturing plant communities.We measured subjective evaluations and objective physiological data from 44 participants who viewed images of plant communities in the yellow to green hue range to compare differences in restorative benefits among plant communities at different visual distances,as well as quantifying the influencing factors involved.The following results were found:(1)Coniferous and multi-layered plant communities were found to provide greater restorative benefits,and the restorative benefits grew with increasing visual distance.(2)Shape and color characteristics were significantly correlated with restorative benefits,but the relationship is not simply linear.(3)The restorative benefits were found to be greatest when crown proportion was 61.23%,trunk proportion ranged from 4.11%to 13.70%,and the value of color index value ranged from 25.44%to 35.56%;the restorative benefits gradually increased when sky proportion exceeded 12.95%-13.19%,the fractal dimension exceeded 1.62-1.67,and hue index exceeded 91.64°-95.67°;additionally,the restorative benefits decreased when the saturation index increased.This study provides a scientific basis for the construction and improvement of plant landscapes in urban green spaces.展开更多
Robust teleoperation in image-guided interventions faces critical challenges from latency,deformation,and the quasi-periodic nature of physiological motion.This paper presents a fully integrated,latency-aware visual s...Robust teleoperation in image-guided interventions faces critical challenges from latency,deformation,and the quasi-periodic nature of physiological motion.This paper presents a fully integrated,latency-aware visual servoing system leveraging stereo vision,hand–eye calibration,and learning-based prediction for motion-compensated teleoperation.The system combines a calibrated binocular camera setup,dual robotic arms,and a predictive control loop incorporating Long Short-Term Memory(LSTM)and Temporal Convolutional Network(TCN)models.Through experiments using both in vivo and phantom datasets,we quantitatively assess the prediction accuracy and motion-compensation performance of both models.Results show that TCNs deliver more stable and precise tracking,especially on regular trajectories,while LSTMs exhibit robustness under quasi-periodic dynamics.By matching prediction horizons to system latency,the approach significantly reduces peak and steady-state tracking errors,demonstrating practical feasibility for deploying prediction-augmented servoing in teleoperated surgical.展开更多
Responsive colorimetric materials exhibit significant potential for application in fields such as smart food packaging and wound monitoring.The functional integration of pH-indicators with material carriers enables br...Responsive colorimetric materials exhibit significant potential for application in fields such as smart food packaging and wound monitoring.The functional integration of pH-indicators with material carriers enables breakthrough applications in nontraditional domains.In this study,we developed a novel material covalently grafted with a pH indicator that exhibited naked-eye pH-responsive color shifts.The covalent grafting of pH-responsive bromothymol blue onto carboxymethyl cellulose(CMC)was confirmed using advanced characterization techniques,including Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy.The pH-sensitive chromophore was covalently immobilized onto the CMC matrix through esterification,thereby establishing firm chemical conjugation.Moreover,a superior color-changing performance was achieved within several minutes in response to different pH values.The reusability and stability of this material offer distinct advantages over single-use pH test strips.pH-responsive colorimetric materials hold promise for efficient,noninvasive monitoring in intelligent packaging(food freshness),medical diagnostics(wound status,infections),biosensing,and environmental applications.展开更多
AIM:To assess the visual acuity and visual quality of cataract patients who received femtosecond laser-assisted cataract surgery(FLACS)and multifocal intraocular lens(MIOL)implantation with an improved polishing techn...AIM:To assess the visual acuity and visual quality of cataract patients who received femtosecond laser-assisted cataract surgery(FLACS)and multifocal intraocular lens(MIOL)implantation with an improved polishing technique during a 1-year follow-up period.METHODS:This study included 74 eyes from 37 patients,comprising 17 males and 20 females,with a mean age of 51.74±7.80 years.Using a coin toss method,one eye per patient was randomly selected for improved anterior capsular polishing,while the other eye received standard irrigation/aspiration(I/A)polishing.The polishing group consisted of 37 eyes,including 21 right and 16 left eyes,while the control group comprised the contralateral fellow eyes of the same individuals in the polishing group.Visual acuity and quality of the patients were evaluated before surgery and at 1 wk,1,6,and 12 mo after surgery.The OPD-Scan III was utilized to assess high-order aberrations,while the optical quality analysis system(OQAS)was employed to evaluate modulation transfer function(MTF cutoff),Strehl ratio(SR),and objective scatter index(OSI)for the purpose of visual quality assessment.Paired t-tests and repeated measures analysis of variance(ANOVA)were utilized to compare the results,and the SNK-q post hoc test was applied to identify significant differences.RESULTS:The polishing group’s uncorrected distant visual acuity(UDVA)and uncorrected near visual acuity(UNVA)significantly improved 1-week post-surgery(all P<0.05).At 12-months,UDVA,UNVA,and corrected distant visual acuity(CDVA)were better than the control group(P<0.05).The MTF cutoff,SR,OSI,and high-order aberrations in the polishing group also showed significant improvements compared to the control group at 12 mo(P<0.05).CONCLUSION:The improved capsular polishing method has been demonstrated to effectively maintain visual acuity and visual quality in patients with MIOL after FLACS within 1 a.展开更多
With the rapid development of generative artificial intelligence(GenAI),the task of story visualization,which transforms natural language narratives into coherent and consistent image sequences,has attracted growing r...With the rapid development of generative artificial intelligence(GenAI),the task of story visualization,which transforms natural language narratives into coherent and consistent image sequences,has attracted growing research attention.However,existing methods still face limitations in balancing multi-frame character consistency and generation efficiency,which restricts their feasibility for large-scale practical applications.To address this issue,this study proposes a modular cloud-based distributed system built on Stable Diffusion.By separating the character generation and story generation processes,and integratingmulti-feature control techniques,a cachingmechanism,and an asynchronous task queue architecture,the system enhances generation efficiency and scalability.The experimental design includes both automated and human evaluations of character consistency,performance testing,and multinode simulation.The results show that the proposed system outperforms the baseline model StoryGen in both CLIP-I and human evaluation metrics.In terms of performance,under the experimental environment of this study,dual-node deployment reduces average waiting time by approximately 19%,while the four-node simulation further reduces it by up to 65%.Overall,this study demonstrates the advantages of cloud-distributed GenAI in maintaining character consistency and reducing generation latency,highlighting its potential value inmulti-user collaborative story visualization applications.展开更多
AIM:To evaluate the clinical characteristics and risk factors associated with visual prognosis in patients with open globe injuries(OGIs)treated at Vietnam National Eye Hospital.METHODS:A prospective observational stu...AIM:To evaluate the clinical characteristics and risk factors associated with visual prognosis in patients with open globe injuries(OGIs)treated at Vietnam National Eye Hospital.METHODS:A prospective observational study included patients with OGIs treated between June 2023 and June 2024.Data on demographics,injury features,and clinical findings were extracted from medical records.Poor visual outcome was defined as final best-corrected visual acuity(BCVA)worse than 20/400 or no light perception.Multivariable logistic regression was performed to identify independent risk factors.RESULTS:Among 509 patients(636 eyes),the mean age was 35.13y(range 20–51y),and 67.6%were male.After treatment,the proportion of eyes achieving≥20/40 increased from 12.6%to 42.1%,while no light perception decreased from 29.1%to 9.4%.Independent predictors of poor visual outcomes included delayed admission[>4h,odds ratio(OR)=3.33,95%confidence intervals(CI):1.76–6.33,P<0.001],Zone III injury(OR=5.90,95%CI:2.85–12.24,P<0.001),wound length>10 mm(OR=2.59,95%CI:1.60–4.18,P<0.001),relative afferent pupillary defect(RAPD,OR=1.65,95%CI:1.03–2.64,P=0.039),endophthalmitis(OR=1.75,95%CI:1.01–3.03,P=0.047),retinal detachment(OR=3.32,95%CI:2.02–5.45,P<0.001),and eyelid lacerations(OR=1.94,95%CI:1.13–3.33,P=0.016)associated with OGIs.Vitreous hemorrhage(OR=0.44,95%CI:0.22–0.89,P=0.023)was associated with better outcomes,and female gender appeared protective.CONCLUSION:Poor visual outcomes remain common after OGIs,despite improve visual acuity in many cases.Several clinical and injury-related factors are strongly associated with prognosis.Early recognition of these predictors can support risk stratification and improve trauma care in similar settings.展开更多
为有效进行水库地下渗流预测,本文以某水库为例,通过对坝址区地质、水文等基本条件的了解,提出基于Visual Mod flow模拟的水库地下渗流预测方案。考虑天然、蓄水及防渗帷幕多种坝址区地下水工况,利用地下水渗流模型进行模拟分析,预测坝...为有效进行水库地下渗流预测,本文以某水库为例,通过对坝址区地质、水文等基本条件的了解,提出基于Visual Mod flow模拟的水库地下渗流预测方案。考虑天然、蓄水及防渗帷幕多种坝址区地下水工况,利用地下水渗流模型进行模拟分析,预测坝址区渗漏量,根据水库渗漏情况采取防渗措施,使水库安全、稳定运行。研究认为,蓄水水位1850 m较为合适,成库条件良好,水库维持此水位运行时具有较高的经济效益和生态效益。本研究对水库地下渗流预测提供参考,采用科学的方法保证水库地下渗流预测结果的可靠性,结合完善的防渗措施,提高水库建设水平和运行水平。展开更多
文摘针对触摸屏监控系统不能满足大中型立体仓库对数据进行存储和处理的功能需求,在Visual Studio 2019集成开发环境中,采用C#语言开发一套立体仓库上位机控制系统。以多线程的方式实时读取库位信息;以S7-1200 PLC作为主控制器,设计产品的自动入库和自动出库程序流程,采用SCL语言设计了库位先进先出的控制程序。C#和S7-1200 PLC之间采用S7通信的方式控制立体仓库的出入库操作和库位信息采集,3年的现场运行情况表明,整个系统能在上位机上对立体仓库进行手动控制和自动控制,能精确快速地进行入库出库操作,运行平稳,上位机上能正确实时显示库位信息,达到了预期的结果。
基金supported by the National Natural Science Foundation of China,No.82271115(to MY).
文摘Synaptic plasticity is essential for maintaining neuronal function in the central nervous system and serves as a critical indicator of the effects of neurodegenerative disease.Glaucoma directly impairs retinal ganglion cells and their axons,leading to axonal transport dysfuntion,subsequently causing secondary damage to anterior or posterior ends of the visual system.Accordingly,recent evidence indicates that glaucoma is a degenerative disease of the central nervous system that causes damage throughout the visual pathway.However,the effects of glaucoma on synaptic plasticity in the primary visual cortex remain unclear.In this study,we established a mouse model of unilateral chronic ocular hypertension by injecting magnetic microbeads into the anterior chamber of one eye.We found that,after 4 weeks of chronic ocular hypertension,the neuronal somas were smaller in the superior colliculus and lateral geniculate body regions of the brain contralateral to the affected eye.This was accompanied by glial cell activation and increased expression of inflammatory factors.After 8 weeks of ocular hypertension,we observed a reduction in the number of excitatory and inhibitory synapses,dendritic spines,and activation of glial cells in the primary visual cortex contralateral to the affected eye.These findings suggest that glaucoma not only directly damages the retina but also induces alterations in synapses and dendritic spines in the primary visual cortex,providing new insights into the pathogenesis of glaucoma.
文摘AIM:To compare the visual outcomes between bilateral implantation of Tecnis ZXR00 extended depth-of-focus(EDOF)intraocular lenses(IOLs)and mixed implantation of Tecnis ZXR00(EDOF)with Tecnis ZMB00(bifocal)IOLs.METHODS:This postoperative cross-sectional study enrolled patients who underwent phacoemulsification combined with IOL implantation.Patients were divided into two groups:the bilateral ZXR00 group(ZXR00-only group)and the mixed IOL group(ZXR00+ZMB00 group).Primary outcome measures included uncorrected and corrected distance visual acuity(UDVA,CDVA),uncorrected and distance-corrected near visual acuity(UNVA,DCNVA),uncorrected and distance-corrected intermediate visual acuity(UIVA,DCIVA),and defocus curves.Secondary outcome measures were visual quality,spectacle independence,patient satisfaction,photic phenomena,and stereopsis.RESULTS:A total of 47 patients(94 eyes)were included,with 26 patients(11 males,15 females)in the ZXR00-only group(mean age:62.73±7.24y)and 21 patients(7 males,14 females)in the mixed group(mean age:65.71±9.16y).There was no statistically significant difference in age between the two groups(P=0.218).The mixed group showed significantly better binocular DCNVA compared to the ZXR00-only group(P=0.002).Defocus curve analysis revealed that the mixed group exhibited superior performance at−2.5 to−4.0 D but inferior performance at−0.5 and−1.5 D.Near stereoacuity was significantly poorer in the mixed group(Randot:5.589±0.744 vs 6.240±0.394 ln arcsec;Contour:4.966±0.973 vs 5.740±0.833 ln arcsec;both P<0.01).Both groups achieved high levels of spectacle independence and patient satisfaction,with no significant differences in photic phenomena or questionnaire scores.CONCLUSION:Mixed implantation of EDOF and bifocal IOLs improve near visual acuity but may compromise near stereopsis.This approach provides a viable option for patients prioritizing near vision;however,caution is recommended for individuals requiring fine stereoscopic vision for daily or professional tasks.
基金supported by the National Natural Science Foundation of China(62421004,U24A20279,62473243,62533004)。
文摘Dear Editor,This letter addresses the formation control problem for unmanned surface vehicles(USVs)under GPS-denied environments.A novel visual servo formation control scheme,utilizing a monocular camera on the follower to obtain the leader’s global position,is developed,which is also capable of guaranteeing collision avoidance and visibility maintenance(CA&VM)raised by the requirement of actual formation navigation.
基金supported by Post-Moore Major Project of the National Natural Science Foundation of China(Grant No.92364204)Zhejiang Province introduces and cultivates leading innovation and entrepreneurship teams(Grant No.2023R01011)+1 种基金Zhejiang Provincial Natural Science Foundation of China(Grant No.LMS25F040005)the Key R&D Program of Zhejiang(Grant No.2024SSYS0042)。
文摘Neuromorphic visual perception,by emulating the efficient information processing mechanisms of biological vision systems and integrating innovations in materials and device architectures,offers novel solutions for artificial intelligence sensing.For instance,the incorporation of low-dimensional materials(e.g.,quantum dots,carbon nanotubes,and two-dimensional materials)optimizes device optoelectronic properties,while the synergistic design of organic semiconductors and oxide materials balances flexibility with complementary metal-oxide-semiconductor(CMOS)compatibility.Representative neuromorphic devices such as memristors and neuromorphic transistors address traditional vision system bottlenecks via near-sensor and in-sensor architectures in data transmission latency and energy consumption,offering a new paradigm for highly integrated,energy-efficient real-time perception.However,critical challenges—including device non-uniformity caused by material interface defects,system instability induced by memristor conductance drift,and environmental adaptability under complex illumination—remain barriers to scalable applications.This review comprehensively examines neuromorphic visual perception devices from the perspectives of device structure,operational mechanisms,materials,and applications.It explores the pivotal roles of memristors,electrolyte-gated transistors,and other neuromorphic devices in optical signal perception and information processing,with a focus on their implementations in visual perception tasks and future prospects.
基金supported by STI 2030-Major Projects,No.2022ZD0208503(to DY)the Fund of Chinese Academy of Science(“Xi Bu Zhi Guang”Project)(to YY)the Sichuan Science and Technology Program,No.2023YFS0312(to YY).
文摘While degenerative diseases of the central nervous system are commonly linked to age-related macular degeneration and glaucoma,they have also been infrequently associated with retinitis pigmentosa,a condition defined by retinal degeneration that can be caused by an isoform of receptor expression enhancing protein 6(REEP6)expressed in rod photoreceptors.In this study,we used REEP6 knockout mice(REEP6^(-/-))and wild-type mice(REEP6^(+/+))to examine neurodegenerative pathology within the visual pathways and neural activity in the primary visual cortex(V1)at three specific time points(1,6,and 10 months)during retinitis pigmentosa progression.Microglial activation was observed in both the retina and the primary visual cortex starting at 1 month of age,but no such activation was detected in the lateral geniculate nucleus at any time point.Not only was increased microglial activation observed at 6 and 10 months within the primary visual cortex of REEP6^(-/-)mice,but also coinciding with elevated levels of phosphorylated Tau expression.At 6 and 10 months of age,primary visual cortex neurons in REEP6^(-/-)mice exhibited reduced responses to grating stimuli and increased spontaneous activity compared with neurons in the primary visual cortex of mice in the control group.Our findings show that retinitis pigmentosa induces neurodegenerative pathology within the visual pathway of mice,particularly in the primary visual cortex,suggesting that ocular disease contributes substantially to central nervous system degeneration.It may provide new clues for the selection of treatment opportunities and the development of therapeutic measures for the subsequent treatment of retinitis pigmentosa or even other retinal degenerative diseases.
基金Project supported by the Postgraduate Research&Practice Innovation Program of Jiangsu Province(Grant No.KYCX240139)funded by the Youth Independent Innovation Fund of PLA Army Engineering University(Grant No.KYJBJKQTZQ23006)。
文摘This study extends the self-propelled particle(SPP)model by incorporating a limited vision cone and local density sensing.The results reveal that clusters can simultaneously exhibit velocity polarization and spatial cohesion within specific ranges of vision angle and density threshold.The dependence of the dynamical features,including the order parameter and density variation,on the threshold and visual cone is investigated.Furthermore,a critical threshold is identified,which governs the transition between ordered and disordered states and is closely linked to density fluctuations and noise intensity.The clustering results show that the model is explained by the chasing mechanism responsible for cluster formation,density,and shape.These results may stimulate practical applications in swarm maneuvering.
基金Supported by The Eye Hospital of Wenzhou Medical University(No.KYQD20220304)The Fifth Batch of Provincial Ten Thousand Personnel Program Outstanding Talents Funding(No.474092204)+1 种基金Innovative Talents and Teams(2024)-The Fifth Batch of Funding Funds for Scientific and Technological Innovation Leading Talents Under the Provincial Ten Thousand Personnel Program(No.4240924003G)The Key R&D Program of Zhejiang(No.2022C03112).
文摘AIM:To identify early biomarkers associated with glaucomatous visual field(VF)progression in patients with normal-tension glaucoma(NTG).METHODS:This study included patients were divided into two groups based on disease progression status.Tear samples were collected for proteomic analysis.Dataindependent acquisition(DIA)mass spectrometry combined with bioinformatic analyses was performed to identify and validate potential protein biomarkers for NTG progression.Additionally,differentially expressed proteins(DEPs)were evaluated using mediating effect models and receiver operating characteristic(ROC)curve analysis.RESULTS:A total of 19 patients(20 eyes)with NTG participated in this study,including 10 patients(4 males and 6 females;10 eyes)in the progression group with mean age of 67.70±9.03y and 10 patients(4 males and 6 females;10 eyes)in the non-progression group with mean age of 68.60±7.58y.A total of 158 significantly differentially expressed proteins were detected.UniProt database annotation identified 3 upregulated proteins and 12 downregulated proteins.Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway analysis showed that these DEPs were mainly enriched in pathways such as oocyte meiosis.Gene Ontology(GO)enrichment analysis revealed functional clusters related to cellular processes.Weighted gene coexpression network analysis(WGCNA)indicated that the core proteins were primarily involved in the neurodegenerationmultiple diseases pathway and cellular processes.Mediating effect analysis identified PRDX4(L)as a potential protein biomarker.ROC curve analysis showed that GNAI1 had the largest area under the curve(AUC=0.889).CONCLUSION:This study identifies 15 differentially expressed proteins in the tear fluid of NTG patients,including PRDX4(L).PRDX4(L)plays a key role in oxidative stress.
基金funded by the National Natural Science Foundation of China(32471953)the Educational Department of Liaoning Province Key Research Project(LJ212410153073).
文摘Urban green spaces have positive effects on both physical and mental wellbeing.However,few studies have focused on the trends and thresholds of the effects of different influences on restorative benefits when viewing scenes differfeaturing plant communities.We measured subjective evaluations and objective physiological data from 44 participants who viewed images of plant communities in the yellow to green hue range to compare differences in restorative benefits among plant communities at different visual distances,as well as quantifying the influencing factors involved.The following results were found:(1)Coniferous and multi-layered plant communities were found to provide greater restorative benefits,and the restorative benefits grew with increasing visual distance.(2)Shape and color characteristics were significantly correlated with restorative benefits,but the relationship is not simply linear.(3)The restorative benefits were found to be greatest when crown proportion was 61.23%,trunk proportion ranged from 4.11%to 13.70%,and the value of color index value ranged from 25.44%to 35.56%;the restorative benefits gradually increased when sky proportion exceeded 12.95%-13.19%,the fractal dimension exceeded 1.62-1.67,and hue index exceeded 91.64°-95.67°;additionally,the restorative benefits decreased when the saturation index increased.This study provides a scientific basis for the construction and improvement of plant landscapes in urban green spaces.
基金Support by Sichuan Science and Technology Program[2023YFSY0026,2023YFH0004]Guangzhou Huashang University[2024HSZD01,HS2023JYSZH01].
文摘Robust teleoperation in image-guided interventions faces critical challenges from latency,deformation,and the quasi-periodic nature of physiological motion.This paper presents a fully integrated,latency-aware visual servoing system leveraging stereo vision,hand–eye calibration,and learning-based prediction for motion-compensated teleoperation.The system combines a calibrated binocular camera setup,dual robotic arms,and a predictive control loop incorporating Long Short-Term Memory(LSTM)and Temporal Convolutional Network(TCN)models.Through experiments using both in vivo and phantom datasets,we quantitatively assess the prediction accuracy and motion-compensation performance of both models.Results show that TCNs deliver more stable and precise tracking,especially on regular trajectories,while LSTMs exhibit robustness under quasi-periodic dynamics.By matching prediction horizons to system latency,the approach significantly reduces peak and steady-state tracking errors,demonstrating practical feasibility for deploying prediction-augmented servoing in teleoperated surgical.
基金financially supported by the National Natural Science Foundation of China(No.52303209)the“Lingyan”Program of Zhejiang Province(No.2024C03076)+1 种基金Zhejiang University K.P.Chao’s High Technology Development Foundationthe generous support provided by the joint research fund from the Shaoxing Institute of Zhejiang University and Shaoxing Maternity and Child Health Care Hospital。
文摘Responsive colorimetric materials exhibit significant potential for application in fields such as smart food packaging and wound monitoring.The functional integration of pH-indicators with material carriers enables breakthrough applications in nontraditional domains.In this study,we developed a novel material covalently grafted with a pH indicator that exhibited naked-eye pH-responsive color shifts.The covalent grafting of pH-responsive bromothymol blue onto carboxymethyl cellulose(CMC)was confirmed using advanced characterization techniques,including Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy.The pH-sensitive chromophore was covalently immobilized onto the CMC matrix through esterification,thereby establishing firm chemical conjugation.Moreover,a superior color-changing performance was achieved within several minutes in response to different pH values.The reusability and stability of this material offer distinct advantages over single-use pH test strips.pH-responsive colorimetric materials hold promise for efficient,noninvasive monitoring in intelligent packaging(food freshness),medical diagnostics(wound status,infections),biosensing,and environmental applications.
文摘AIM:To assess the visual acuity and visual quality of cataract patients who received femtosecond laser-assisted cataract surgery(FLACS)and multifocal intraocular lens(MIOL)implantation with an improved polishing technique during a 1-year follow-up period.METHODS:This study included 74 eyes from 37 patients,comprising 17 males and 20 females,with a mean age of 51.74±7.80 years.Using a coin toss method,one eye per patient was randomly selected for improved anterior capsular polishing,while the other eye received standard irrigation/aspiration(I/A)polishing.The polishing group consisted of 37 eyes,including 21 right and 16 left eyes,while the control group comprised the contralateral fellow eyes of the same individuals in the polishing group.Visual acuity and quality of the patients were evaluated before surgery and at 1 wk,1,6,and 12 mo after surgery.The OPD-Scan III was utilized to assess high-order aberrations,while the optical quality analysis system(OQAS)was employed to evaluate modulation transfer function(MTF cutoff),Strehl ratio(SR),and objective scatter index(OSI)for the purpose of visual quality assessment.Paired t-tests and repeated measures analysis of variance(ANOVA)were utilized to compare the results,and the SNK-q post hoc test was applied to identify significant differences.RESULTS:The polishing group’s uncorrected distant visual acuity(UDVA)and uncorrected near visual acuity(UNVA)significantly improved 1-week post-surgery(all P<0.05).At 12-months,UDVA,UNVA,and corrected distant visual acuity(CDVA)were better than the control group(P<0.05).The MTF cutoff,SR,OSI,and high-order aberrations in the polishing group also showed significant improvements compared to the control group at 12 mo(P<0.05).CONCLUSION:The improved capsular polishing method has been demonstrated to effectively maintain visual acuity and visual quality in patients with MIOL after FLACS within 1 a.
文摘With the rapid development of generative artificial intelligence(GenAI),the task of story visualization,which transforms natural language narratives into coherent and consistent image sequences,has attracted growing research attention.However,existing methods still face limitations in balancing multi-frame character consistency and generation efficiency,which restricts their feasibility for large-scale practical applications.To address this issue,this study proposes a modular cloud-based distributed system built on Stable Diffusion.By separating the character generation and story generation processes,and integratingmulti-feature control techniques,a cachingmechanism,and an asynchronous task queue architecture,the system enhances generation efficiency and scalability.The experimental design includes both automated and human evaluations of character consistency,performance testing,and multinode simulation.The results show that the proposed system outperforms the baseline model StoryGen in both CLIP-I and human evaluation metrics.In terms of performance,under the experimental environment of this study,dual-node deployment reduces average waiting time by approximately 19%,while the four-node simulation further reduces it by up to 65%.Overall,this study demonstrates the advantages of cloud-distributed GenAI in maintaining character consistency and reducing generation latency,highlighting its potential value inmulti-user collaborative story visualization applications.
文摘AIM:To evaluate the clinical characteristics and risk factors associated with visual prognosis in patients with open globe injuries(OGIs)treated at Vietnam National Eye Hospital.METHODS:A prospective observational study included patients with OGIs treated between June 2023 and June 2024.Data on demographics,injury features,and clinical findings were extracted from medical records.Poor visual outcome was defined as final best-corrected visual acuity(BCVA)worse than 20/400 or no light perception.Multivariable logistic regression was performed to identify independent risk factors.RESULTS:Among 509 patients(636 eyes),the mean age was 35.13y(range 20–51y),and 67.6%were male.After treatment,the proportion of eyes achieving≥20/40 increased from 12.6%to 42.1%,while no light perception decreased from 29.1%to 9.4%.Independent predictors of poor visual outcomes included delayed admission[>4h,odds ratio(OR)=3.33,95%confidence intervals(CI):1.76–6.33,P<0.001],Zone III injury(OR=5.90,95%CI:2.85–12.24,P<0.001),wound length>10 mm(OR=2.59,95%CI:1.60–4.18,P<0.001),relative afferent pupillary defect(RAPD,OR=1.65,95%CI:1.03–2.64,P=0.039),endophthalmitis(OR=1.75,95%CI:1.01–3.03,P=0.047),retinal detachment(OR=3.32,95%CI:2.02–5.45,P<0.001),and eyelid lacerations(OR=1.94,95%CI:1.13–3.33,P=0.016)associated with OGIs.Vitreous hemorrhage(OR=0.44,95%CI:0.22–0.89,P=0.023)was associated with better outcomes,and female gender appeared protective.CONCLUSION:Poor visual outcomes remain common after OGIs,despite improve visual acuity in many cases.Several clinical and injury-related factors are strongly associated with prognosis.Early recognition of these predictors can support risk stratification and improve trauma care in similar settings.
文摘为有效进行水库地下渗流预测,本文以某水库为例,通过对坝址区地质、水文等基本条件的了解,提出基于Visual Mod flow模拟的水库地下渗流预测方案。考虑天然、蓄水及防渗帷幕多种坝址区地下水工况,利用地下水渗流模型进行模拟分析,预测坝址区渗漏量,根据水库渗漏情况采取防渗措施,使水库安全、稳定运行。研究认为,蓄水水位1850 m较为合适,成库条件良好,水库维持此水位运行时具有较高的经济效益和生态效益。本研究对水库地下渗流预测提供参考,采用科学的方法保证水库地下渗流预测结果的可靠性,结合完善的防渗措施,提高水库建设水平和运行水平。
