A new case representation is proposed. Design process is included in this case representation. The record of design process provides designers with rationale and assumptions behind design solutions. This kind of case ...A new case representation is proposed. Design process is included in this case representation. The record of design process provides designers with rationale and assumptions behind design solutions. This kind of case representation not only provides better understanding of design solutions among designers, but also helps designers create new solutions in case modification stage.展开更多
The production model of“multi-specification and low-quantity”is becoming the main trend of manufacturing industry.As a key activity in the manufacturing chain,traditional computer aided process planning(CAPP)system ...The production model of“multi-specification and low-quantity”is becoming the main trend of manufacturing industry.As a key activity in the manufacturing chain,traditional computer aided process planning(CAPP)system fails to adapt to the production model of customization.Therefore,a novel method for variant design of process planning was proposed to develop CAPP system based on Tabular Layouts of Article Characteristics(Sach-Merk Leisten in German and SML for short). With the support of standard database of master process planning documents which are developed by parameterization technique, and instance process planning for special product(instance product)can be generated automatically by the sub-system of variant de- sign of process planning.Finally,a CAPP system was developed for process design of rotor of steam turbine to validate the feasibil- ity and applicability of the method.展开更多
The paper gives a detail analysis on the necessity of rapid hydraulic support design, and presents a computer-aided rapid variant design system for hydraulic support. The system integrates the type selection and embod...The paper gives a detail analysis on the necessity of rapid hydraulic support design, and presents a computer-aided rapid variant design system for hydraulic support. The system integrates the type selection and embodiment design of hydraulic support. Case-based reasoning and rule-based reasoning are the main reasoning methods. Several crucial problems are discussed.展开更多
In order to accelerate the product design and shorten the development cycle, the product design base on Top-Down and product level parametric design method. Based on the 2K-V type of product structure tree, the mappin...In order to accelerate the product design and shorten the development cycle, the product design base on Top-Down and product level parametric design method. Based on the 2K-V type of product structure tree, the mapping of the structure tree to the hierarchical skeleton feature tree is completed and the modeling of the~ product＇s 3D cascade skeleton is built with Pro/E skeleton Technology. The skeleton model is the basis of assembly, then to build the framework of the model＇s cascade constraints and to realize the whole model driven by the top skeleton parameters. The designers can build new models in the design of the similar structure through the rapid variant design of top skeleton parameters展开更多
The development of technologies such as big data and cyber-physical systems （CPSs） has increased the demand for product design. Product digital design involves completing the product design process using advanced di...The development of technologies such as big data and cyber-physical systems （CPSs） has increased the demand for product design. Product digital design involves completing the product design process using advanced digital technologies such as geometry modeling, kinematic and dynamic simulation, multi- disciplinary coupling, virtual assembly, virtual reality （VR）, multi-objective optimization （MOO）, and human-computer interaction. The key technologies of intelligent design for customized products include： a description and analysis of customer requirements （CRs）, product family design （PFD） for the customer base, configuration and modular design for customized products, variant design for customized products, and a knowledge push for product intelligent design. The development trends in intelligent design for customized products include big-data-driven intelligent design technology for customized products and customized design tools and applications. The proposed method is verified by the design of precision computer numerical control （CNC） machine tools.展开更多
Based on introduction characteristics and classific at ion of Mass Customization (MC), the paper expounds foundations and design me thods of MC. The foundations of MC production are standardization, seriation and norm...Based on introduction characteristics and classific at ion of Mass Customization (MC), the paper expounds foundations and design me thods of MC. The foundations of MC production are standardization, seriation and normality of production, guiding thought of Concurrent Engineering (CE), ap plication of CAD/CAM technology and etc. And design methods of MC products are d esign for product family, modular design, parameterization CAD, variant design, design for manufacturing (DFM) and design by customers. Design for product famil y is a method that first to design a basic form of the product, and then to with draw variant parameters to become a variable product model, makes a family or a series of product design at the same time. Modular design is that based on produ ct function analysis of different function or the same function but different sp ecification within a certain scope, divides and designs out a series of function modular, and through selection and combination of the modular can make up diffe rent products. Parameterization CAD is a CAD method that has function of dimensi on drive. Variant design is a method that under circumstance of keeping principl e constant and construction similar or likeness, properly adjusts part of constr uction and design parameters to adapt design demands. DFM demands the designer t o consider problems that will appear in manufacture in the stage of design, and to avoid them through optimal design. And design by customers is guiding custome rs to design within the scope of production capacity of enterprise and optional items that enterprise has designed to satisfy their requirements of form, functi on and price. Among them modular design, parameterization CAD and variant design are key technology of design methods of MC products. And design by customers is a main characteristic of design of customization product, and an effective sale means also.展开更多
The current research of configurable product design mainly focuses on how to convert a predefined set of components into a valid set of product structures. With the scale and complexity of configurable products increa...The current research of configurable product design mainly focuses on how to convert a predefined set of components into a valid set of product structures. With the scale and complexity of configurable products increasing, the interdependencies between customer demands and product structures grow up as well. The result is that existing product structures fails to satisfy the individual customer requirements and hence product variants are needed. This paper is aimed to build a bridge between customer demands and product structures in order to make demand-driven fast response design feasible. First of all, multi-hierarchical models of configurable product design are established with customer demand model, technical requirement model and product structure model. Then, the transition of multi-hierarchical models among customer demand model, technical requirement model and product structure model is solved with fuzzy analytic hierarchy process （FAHP） and the algorithm of multi-level matching. Finally, optimal structure according to the customer demands is obtained with the calculation of Euclidean distance and similarity of some cases. In practice, the configuration design of a clamping unit of injection molding machine successfully performs an optimal search strategy for the product variants with reasonable satisfaction to individual customer demands. The proposed method can automatically generate a configuration design with better alternatives for each product structures, and shorten the time of finding the configuration of a product.展开更多
Aiming at the problems of low-level information sharing, slow transmission and repetitive work in the designing process of product series, the internet-oriented parametric collaborative design method is proposed, in w...Aiming at the problems of low-level information sharing, slow transmission and repetitive work in the designing process of product series, the internet-oriented parametric collaborative design method is proposed, in which the problems of sharing conflict and network heterogeneous in the distributed collaborative design are analyzed, and the construction method of collaborative design platforms based on PDMWorks Workgroup is put forward. Through studying the mechanism of roles distribution and function allocation and data concurrency control, the communication mechanism of internet-oriented collaborative design is formulated. On the basis of structure features of overhead travelling crane, through combining parametric variant design with collaborative design, internet-oriented parametric collaborative design system of overhead travelling crane is developed and verified through main girder design. In the paper, the internet-oriented parametric collaborative design method is proposed, aiming to solve the problems of low-level information sharing, slow transmission and repetitive work in the designing process of product series. The problems of sharing conflict and network heterogeneous in the distributed collaborative design are analyzed. The construction method of collaborative design platforms based on PDMWorks Workgroup is put forward. The communication mechanism of internet-oriented collaborative design is formulated, through studying the mechanism of roles distribution and function allocation and data concurrency control. On the basis of structure features of overhead travelling crane, through combining parametric variant design with collaborative design, internet-oriented parametric collaborative design system of overhead travelling crane is developed and verified through main girder design.展开更多
The conception of flexible constraint is proposed in the paper. The solution of flexible constraint is in special range, and maybe different in different instances of same design scheme. The paper emphasis on how to e...The conception of flexible constraint is proposed in the paper. The solution of flexible constraint is in special range, and maybe different in different instances of same design scheme. The paper emphasis on how to evaluate and optimize a design scheme with flexible constraints based on the satisfaction degree function defined on flexible constraints. The conception of flexible constraint is used to solve constraint conflict and design optimization in complicated constraint based assembly design by the PFM parametrization assembly design system. An instance of gear box design is used for verifying optimization method.展开更多
目的依据全球最新的分析方法质量源于设计(Analysis Quality by Design,AQbD)和全生命周期理念,建立适用于新型冠状病毒Omicrion XBB.1.5变异株的临床中和抗体和流行病学调查用中和抗体检测方法。方法在已建立的新型冠状病毒原型株中和...目的依据全球最新的分析方法质量源于设计(Analysis Quality by Design,AQbD)和全生命周期理念,建立适用于新型冠状病毒Omicrion XBB.1.5变异株的临床中和抗体和流行病学调查用中和抗体检测方法。方法在已建立的新型冠状病毒原型株中和抗体(CPE法)检测方法的基础上,针对XBB.1.5变异株变更对中和抗体检测方法可能引入的影响因素进行风险评估,对主要风险因素进行条件优化,获得适应XBB.1.5变异株的检测方法,经方法验证明确该方法各项性能指标,并证明方法可满足分析目标概要(Analysis Target Profile,ATP)。结果由XBB.1.5变异株变更引入的主要风险因素为检测细胞、培养基种类和结果判定时间;通过对实验条件优化,最终确定将Vero-E6细胞(DMEM培养基)作为XBB.1.5变异株的最佳培养条件,第5天作为最佳观察时间;经验证得到方法相对准确度和中间精密度的平均相对偏倚为-9.2%~2.9%、几何变异系数(geometric coefficient of variation,GCV)为33.2%~47.1%,满足方法预设ATP,方法误判率低于1.6%。结论依据AQbD和全生命周期的研究理念建立了针对新型冠状病毒XBB.1.5变异株的中和抗体检测方法,经验证该方法满足预设ATP,可用于临床中和抗体和流行病学调查用中和抗体检测。展开更多
目的建立基于实验设计(Design of Experiment,DOE)的SARS-CoV-2中和抗体相对活性检测方法,并进行验证,以期为SARS-CoV-2中和抗体的研发和质量评价提供可靠的检测方法。方法采用SARS-CoV-2变异株假病毒建立用于评价SARS-CoV-2中和抗体相...目的建立基于实验设计(Design of Experiment,DOE)的SARS-CoV-2中和抗体相对活性检测方法,并进行验证,以期为SARS-CoV-2中和抗体的研发和质量评价提供可靠的检测方法。方法采用SARS-CoV-2变异株假病毒建立用于评价SARS-CoV-2中和抗体相对活性的方法,通过DOE优化细胞密度[(3~5)×10^(5)个/mL]、假病毒滴度(3750~6250 TCID50/mL)、抗体与假病毒中和时间(0.5~1.5 h)、抗体假病毒复合物与细胞作用时间(48~96 h),并验证方法的专属性、线性范围、准确性、精密性。采用优化的方法检测2批SARS-CoV-2中和抗体的相对活性。结果确定最佳细胞密度为4×10^(5)个/mL,假病毒滴度为6250 TCID50/mL,抗体与假病毒中和时间为1.5 h,抗体假病毒复合物与细胞作用时间为96 h。仅SARS-CoV-2中和抗体呈典型量效曲线,抗VEGF单克隆抗体和样品稀释液均未呈现量效曲线;SARS-CoV-2中和抗体理论效价在50%~200%范围内与检测值呈良好的线性关系,线性方程为y=1.0342 x-0.013,r=0.9588;50%、71%、100%、141%和200%相对效价水平样品3次检测结果均值的相对偏倚为-6.2%~7.3%,几何变异系数(geometric coefficient of variation,GCV)为3.2%~16.9%。2批SARS-CoV-2中和抗体相对活性分别为91%和118%。结论建立的方法具有良好的专属性、准确性及精密性,可用于SARS-CoV-2中和抗体相对活性的检测。展开更多
文摘A new case representation is proposed. Design process is included in this case representation. The record of design process provides designers with rationale and assumptions behind design solutions. This kind of case representation not only provides better understanding of design solutions among designers, but also helps designers create new solutions in case modification stage.
文摘The production model of“multi-specification and low-quantity”is becoming the main trend of manufacturing industry.As a key activity in the manufacturing chain,traditional computer aided process planning(CAPP)system fails to adapt to the production model of customization.Therefore,a novel method for variant design of process planning was proposed to develop CAPP system based on Tabular Layouts of Article Characteristics(Sach-Merk Leisten in German and SML for short). With the support of standard database of master process planning documents which are developed by parameterization technique, and instance process planning for special product(instance product)can be generated automatically by the sub-system of variant de- sign of process planning.Finally,a CAPP system was developed for process design of rotor of steam turbine to validate the feasibil- ity and applicability of the method.
文摘The paper gives a detail analysis on the necessity of rapid hydraulic support design, and presents a computer-aided rapid variant design system for hydraulic support. The system integrates the type selection and embodiment design of hydraulic support. Case-based reasoning and rule-based reasoning are the main reasoning methods. Several crucial problems are discussed.
文摘In order to accelerate the product design and shorten the development cycle, the product design base on Top-Down and product level parametric design method. Based on the 2K-V type of product structure tree, the mapping of the structure tree to the hierarchical skeleton feature tree is completed and the modeling of the~ product＇s 3D cascade skeleton is built with Pro/E skeleton Technology. The skeleton model is the basis of assembly, then to build the framework of the model＇s cascade constraints and to realize the whole model driven by the top skeleton parameters. The designers can build new models in the design of the similar structure through the rapid variant design of top skeleton parameters
基金The work presented in this article is funded by the National Natural Science Foundation of China （51375012 and 51675478）, the Science and Technology Plan Project of Zhejiang Province （2017C31002）, and the Fundamental Research Funds for the Central Universities （2017FZA4003）.
文摘The development of technologies such as big data and cyber-physical systems （CPSs） has increased the demand for product design. Product digital design involves completing the product design process using advanced digital technologies such as geometry modeling, kinematic and dynamic simulation, multi- disciplinary coupling, virtual assembly, virtual reality （VR）, multi-objective optimization （MOO）, and human-computer interaction. The key technologies of intelligent design for customized products include： a description and analysis of customer requirements （CRs）, product family design （PFD） for the customer base, configuration and modular design for customized products, variant design for customized products, and a knowledge push for product intelligent design. The development trends in intelligent design for customized products include big-data-driven intelligent design technology for customized products and customized design tools and applications. The proposed method is verified by the design of precision computer numerical control （CNC） machine tools.
文摘Based on introduction characteristics and classific at ion of Mass Customization (MC), the paper expounds foundations and design me thods of MC. The foundations of MC production are standardization, seriation and normality of production, guiding thought of Concurrent Engineering (CE), ap plication of CAD/CAM technology and etc. And design methods of MC products are d esign for product family, modular design, parameterization CAD, variant design, design for manufacturing (DFM) and design by customers. Design for product famil y is a method that first to design a basic form of the product, and then to with draw variant parameters to become a variable product model, makes a family or a series of product design at the same time. Modular design is that based on produ ct function analysis of different function or the same function but different sp ecification within a certain scope, divides and designs out a series of function modular, and through selection and combination of the modular can make up diffe rent products. Parameterization CAD is a CAD method that has function of dimensi on drive. Variant design is a method that under circumstance of keeping principl e constant and construction similar or likeness, properly adjusts part of constr uction and design parameters to adapt design demands. DFM demands the designer t o consider problems that will appear in manufacture in the stage of design, and to avoid them through optimal design. And design by customers is guiding custome rs to design within the scope of production capacity of enterprise and optional items that enterprise has designed to satisfy their requirements of form, functi on and price. Among them modular design, parameterization CAD and variant design are key technology of design methods of MC products. And design by customers is a main characteristic of design of customization product, and an effective sale means also.
基金supported by National Natural Science Foundation of China(Grant Nos. 51205350, 51275459)National Science and Technology Major Project of China(Grant No. 2012ZX04010-011)Postdoctoral Research Foundation of Zhejiang Province(Grant No.Bsh1201019)
文摘The current research of configurable product design mainly focuses on how to convert a predefined set of components into a valid set of product structures. With the scale and complexity of configurable products increasing, the interdependencies between customer demands and product structures grow up as well. The result is that existing product structures fails to satisfy the individual customer requirements and hence product variants are needed. This paper is aimed to build a bridge between customer demands and product structures in order to make demand-driven fast response design feasible. First of all, multi-hierarchical models of configurable product design are established with customer demand model, technical requirement model and product structure model. Then, the transition of multi-hierarchical models among customer demand model, technical requirement model and product structure model is solved with fuzzy analytic hierarchy process （FAHP） and the algorithm of multi-level matching. Finally, optimal structure according to the customer demands is obtained with the calculation of Euclidean distance and similarity of some cases. In practice, the configuration design of a clamping unit of injection molding machine successfully performs an optimal search strategy for the product variants with reasonable satisfaction to individual customer demands. The proposed method can automatically generate a configuration design with better alternatives for each product structures, and shorten the time of finding the configuration of a product.
基金supported by the Natural Science Foundation in Shanxi under Grant No. 2008012007Tackle Key Problem Program of Shanxi under Grant No. 20090321024
文摘Aiming at the problems of low-level information sharing, slow transmission and repetitive work in the designing process of product series, the internet-oriented parametric collaborative design method is proposed, in which the problems of sharing conflict and network heterogeneous in the distributed collaborative design are analyzed, and the construction method of collaborative design platforms based on PDMWorks Workgroup is put forward. Through studying the mechanism of roles distribution and function allocation and data concurrency control, the communication mechanism of internet-oriented collaborative design is formulated. On the basis of structure features of overhead travelling crane, through combining parametric variant design with collaborative design, internet-oriented parametric collaborative design system of overhead travelling crane is developed and verified through main girder design. In the paper, the internet-oriented parametric collaborative design method is proposed, aiming to solve the problems of low-level information sharing, slow transmission and repetitive work in the designing process of product series. The problems of sharing conflict and network heterogeneous in the distributed collaborative design are analyzed. The construction method of collaborative design platforms based on PDMWorks Workgroup is put forward. The communication mechanism of internet-oriented collaborative design is formulated, through studying the mechanism of roles distribution and function allocation and data concurrency control. On the basis of structure features of overhead travelling crane, through combining parametric variant design with collaborative design, internet-oriented parametric collaborative design system of overhead travelling crane is developed and verified through main girder design.
文摘The conception of flexible constraint is proposed in the paper. The solution of flexible constraint is in special range, and maybe different in different instances of same design scheme. The paper emphasis on how to evaluate and optimize a design scheme with flexible constraints based on the satisfaction degree function defined on flexible constraints. The conception of flexible constraint is used to solve constraint conflict and design optimization in complicated constraint based assembly design by the PFM parametrization assembly design system. An instance of gear box design is used for verifying optimization method.
文摘目的依据全球最新的分析方法质量源于设计(Analysis Quality by Design,AQbD)和全生命周期理念,建立适用于新型冠状病毒Omicrion XBB.1.5变异株的临床中和抗体和流行病学调查用中和抗体检测方法。方法在已建立的新型冠状病毒原型株中和抗体(CPE法)检测方法的基础上,针对XBB.1.5变异株变更对中和抗体检测方法可能引入的影响因素进行风险评估,对主要风险因素进行条件优化,获得适应XBB.1.5变异株的检测方法,经方法验证明确该方法各项性能指标,并证明方法可满足分析目标概要(Analysis Target Profile,ATP)。结果由XBB.1.5变异株变更引入的主要风险因素为检测细胞、培养基种类和结果判定时间;通过对实验条件优化,最终确定将Vero-E6细胞(DMEM培养基)作为XBB.1.5变异株的最佳培养条件,第5天作为最佳观察时间;经验证得到方法相对准确度和中间精密度的平均相对偏倚为-9.2%~2.9%、几何变异系数(geometric coefficient of variation,GCV)为33.2%~47.1%,满足方法预设ATP,方法误判率低于1.6%。结论依据AQbD和全生命周期的研究理念建立了针对新型冠状病毒XBB.1.5变异株的中和抗体检测方法,经验证该方法满足预设ATP,可用于临床中和抗体和流行病学调查用中和抗体检测。
