but its application is constrained by hepatotoxicity.This study aimed to investigate the feasibility of reducing AAEO’s toxicity through storage and to evaluate changes in chemical composition,toxicity,and bioactivit...but its application is constrained by hepatotoxicity.This study aimed to investigate the feasibility of reducing AAEO’s toxicity through storage and to evaluate changes in chemical composition,toxicity,and bioactivity.Methods:Gas chromatography-mass spectrometry was used to analyze compositional changes during storage.Zebrafish acute toxicity tests and the liver-specific transgenic zebrafish model Tg(fabp10:EGFP)were used to assess toxicity.Antimicrobial,analgesic,and antioxidant assays evaluated variations in bioactivity.Results:Over the 150-day storage period,gas chromatography-mass spectrometry analysis identified 39 components.Zebrafish acute toxicity tests showed that the LD50 of AAEO stored for 0,30,60,90,120,and 150 days were 0.10μL·mL^(-1),0.10μL·mL^(-1),0.10μL·mL^(-1),0.11μL·mL^(-1),0.13μL·mL^(-1),and 0.14μL·mL^(-1),respectively,demonstrating a 40%reduction in acute toxicity after 150 days of storage.Using the liver-specific green fluorescent transgenic Tg(fabp10:EGFP)zebrafish model,the inhibition rates of AAEO on hepatic fluorescence intensity were measured at 68.5%,43.5%,42.6%,37.8%,34.6%,and 31.9% at different time points,confirming reduced hepatotoxicity after storage.Additionally,the antioxidant and analgesic activities of AAEO were significantly enhanced(p<0.05)after storage,while the antibacterial activity decreased(p<0.05).Conclusions:After storage,AAEO significantly reduces hepatotoxicity,with a 40% decrease in acute toxicity after 150 days.Meanwhile,the antioxidant and analgesic activities of AAEO increase,while its antibacterial activity decreases after storage.展开更多
Recently,MnO2 has gained attention as an electrode material because of its very high theoretical capacity and abundant availability.However,the very high volumetric change caused by its conversion-type reaction result...Recently,MnO2 has gained attention as an electrode material because of its very high theoretical capacity and abundant availability.However,the very high volumetric change caused by its conversion-type reaction results in bad reversibility of charge-discharge.In this study,δ-MnO2 of thickness 8 nm anchored on the surface of carbon nanotubes(CNT)by Mn-O-C chemical bonding is synthesized via a facile hydrothermal method.Numerous ex-situ characterizations of the lithium storage process were performed.Furthermore,density functional theory(DFT)calculations indicated thatδ-MnO2(012)thermodynamically prefers bonding with CNTs.Moreover,the interfacial interaction reinforces the connection of Mn-O and reduces the bond strength of Li-O in lithiated MnO2,which could facilitate an intercalation-type lithium storage reaction.Consequently,the as-synthesizedδ-MnO2 retains an excellent reversible capacity of 577.5 mAh g-1 in 1000 cycles at a high rate of 2 A g-1 between 0.1 V and 3.0 V.The results of this study demonstrate the possibility of employing the cost-effective transition metal oxides as intercalation lithium storage dominant electrodes for advanced rechargeable batteries.展开更多
Membrane gas separation is one of the most promising technologies for the separation of carbon dioxide （CO2） from various gas streams. One application of this technology is the treatment of flue gases from combustio...Membrane gas separation is one of the most promising technologies for the separation of carbon dioxide （CO2） from various gas streams. One application of this technology is the treatment of flue gases from combustion processes for the purpose of carbon capture and storage. For this application, poly（ethylene oxide）-containing block copolymers such as Pebax or PolyActiveTM polymer are well suited. The thin-film composite membrane that is considered in this overview employs PolyActiveTM polymer as a selective layer material. The membrane shows excellent CO2 permeances of up to 4 m^3（STP）.（m^2·h·bar）^-1 （1 bar = 105 Pa） at a carbon dioxide/nitrogen （CO2/N2） selectivity exceeding 55 at ambient temperature. The membrane can be manufactured reproducibly on a pilot scale and mounted into fiat-sheet membrane modules of different designs. The operating performance of these modules can be accurately predicted by specifically developed simulation tools, which employ single-gas permeation data as the only experimental input. The performance of membranes and modules was investigated in different pilot plant studies, in which flue gas and biogas were used as the feed gas streams. The investigated processes showed a stable separation performance, indicating the applicability of PolyActiveTM polymer as a membrane material for industrialscale gas processing.展开更多
In this paper, a holographic storage scheme for multimedia data storage and retrieval based on the digital signal processing (DSP) is designed. A communication model for holographic storage system is obtained on the a...In this paper, a holographic storage scheme for multimedia data storage and retrieval based on the digital signal processing (DSP) is designed. A communication model for holographic storage system is obtained on the analogy of traditional communication system. Many characteristics of holographic storage are embodied in the communication model. Then some new methods of DSP including two-dimensional (2-D) shifting interleaving, encoding and decoding of modulation-array (MA) code and method of soft-decision, etc. are proposed and employed in the system. From the results of experiments it can be seen that those measures can effectively reduce the influence of noise. A segment of multimedia data, including video and audio data, is retrieved successfully after holographic storage by using those techniques.展开更多
The very wide applications of LTA zeolites,e.g.tritiated water storage,imply that a precise atomic-scale description of the adsorption processes taking place in their structure is crucial.The zeolite structure seems t...The very wide applications of LTA zeolites,e.g.tritiated water storage,imply that a precise atomic-scale description of the adsorption processes taking place in their structure is crucial.The zeolite structure seems to have a catalytic effect on the O_(2)/H_(2)recombination during the storage process after water radiolysis.To look closely at the conditions that could bring O_(2)and H_(2)to this particular point,we have conducted investigations using static DFT and systematic ab initio molecular dynamics calculations.We have investigated the interaction of these two molecules with the sodium cations,on which the adsorption capacity of the Na-LTA zeolite depends.The O_(2)and H_(2)molecules’behaviour inside the cavities is linked to the Na+position and availability.The latter is regulated by the presence of H_(2)O which interacts with Na+in a stronger way than O_(2)and H_(2).Thus,the adsorption studies of different mixtures(O_(2)/H_(2)O,H_(2)/H_(2)O and H_(2)/O_(2))have been carried out to characterise the competition between water and other vip molecules.The absence of an obvious interaction between the adsorbates strongly suggests a potential reaction path involving the catalytic effect of the zeolite.Since we have been able to show that the behaviour of O_(2)and H_(2)molecules is directly affected by the water coverage rate,the reaction path is very likely to be affected too.These results mark a step towards the description of a recombination mechanism between O_(2)and H_(2)in a zeolite structure,a crucial issue for such systems involving tritiated water adsorbed in nanoporous materials.展开更多
Daqu provides microbiota,flavor substances and enzymes for liquor fermentation.Storage after fermentation is an essential stage for the mature of Daqu.However,it is still unclear about the effect of storage on the mic...Daqu provides microbiota,flavor substances and enzymes for liquor fermentation.Storage after fermentation is an essential stage for the mature of Daqu.However,it is still unclear about the effect of storage on the microbiota structure and enzyme profile.Here,this work revealed the variation of microbiota structure and enzyme profile after storage of low-temperature Daqu using amplicon sequencing and proteomic profile analysis.Results showed that the content of acidity significantly increased by 13.79%(P<0.05).The saccharification power,liquefaction power and fermentation power significantly increased by 2.90%,17.32%and 16.04%,respectively(P<0.05).The contents of 3-methyl-1-butanol and 1-octen-3-ol increased by 147.19%and 29.12%,respectively(P<0.05).Lichtheimia,Saccharomyces,Rhizopus,Aspergillus,Pantoea,Lactiplantibacillus,Pichia,Lacticaseibacillus,Pseudo-monas,Linnemannia,Levilactobacillus,Pediococcus,Paenibacillus and Lactobacillus were the major enzyme-producing microbiota(average protein abundance>1%)using proteomic profile analysis.After storage,the relative abundances of Lactobacillus and Aspergillus increased from 2.59%to 17.63%,and 7.53%-33.67%using amplicon sequencing,respectively.The protein abundance of α-amylase produced by Aspergillus increased from 0.05%to 0.11%,and was consistent with variations of the relative abundance of Aspergillus,and the liquefaction power.The protein abundance of lactic acid dehydrogenase produced by Lactobacillus increased from 0.07%to 0.11%,and was consistent with the variation of relative abundance of Lactobacillus.This work revealed the effect of storage on microbioa and enzyme proteomic profile of low-temperature Daqu.It would be beneficial for controlling the storage stage of Daqu,and help improving the quality of Daqu.展开更多
Magneto-structural correlations are of great importance in developing single-molecule magnets(SMMs)for storage and quantum processing of information.In this work,three cyclooctatetraenylido(COT)ligands,namely COT^(TMS...Magneto-structural correlations are of great importance in developing single-molecule magnets(SMMs)for storage and quantum processing of information.In this work,three cyclooctatetraenylido(COT)ligands,namely COT^(TMS1),COT^(TMS2),and COT^(TMS3) equipped with one,two,and three trimethylsilyl(TMS)substituent(s),respectively,were used to prepare the corresponding Er(Ⅲ)complexes,namely[K(DME)_(2)][Er(COT^(TMS1))_(2)](1:DME,1,2-dimethoxyethane),[K(DME)_(2)][Er(COT^(TMS2))_(2)](2),and[K(18-crown-6)_(1.5)][Er(COT^(TMS3))_(2)](3).The complexes,each featuring an Er(Ⅲ)ion sandwiched by two cyclooctatetraenyl rings,possess uni-axial magnetic anisotropy and display single-molecule magnet behaviors with energy barriers of 208(1)K for 1,193(2)K for 2,and 217(18)K for 3,and blocking temperatures of 11,10,and 9 K,respectively.The relaxation times are found to be closely related to the number of TMS substituents,with that of 1 being about 10 times longer than that of 2,and more significantly,100 times longer than that of 3 at the same temperatures.Studies using infrared spectroscopy indicate that the molecular vibrations of the complexes intensify upon increasing the number of TMS substituents in the ligands,resulting in faster magnetic relaxation.Further analyses reveal that the molecular vibrations in these complexes are related to the pre-exponential factor τ_(0) for the Orbach process or C value for the Raman process.展开更多
With the process of medical informatization,medical diagnosis results are recorded and shared in the form of electronic data in the computer.However,the security of medical data storage cannot be effectively protected...With the process of medical informatization,medical diagnosis results are recorded and shared in the form of electronic data in the computer.However,the security of medical data storage cannot be effectively protected and the unsafe sharing of medical data among different institutions is still a hidden danger that cannot be underestimated.To solve the above problems,a secure storage and sharing model of private data based on blockchain technology and homomorphic encryption is constructed.Based on the idea of blockchain decentralization,the model maintains a reliable medical alliance chain system to ensure the safe transmission of data between different institutions;A privacy data encryption and computing protocol based on homomorphic encryption is constructed to ensure the safe transmission of medical data;Using its complete anonymity to ensure the Blockchain of medical data and patient identity privacy;A strict transaction control management mechanism of medical data based on Intelligent contract automatic execution of preset instructions is proposed.After security verification,compared with the traditional medical big data storage and sharing mode,the model has better security and sharing.展开更多
基金supported by grants from the National Natural Science Foundation of China(82074026)the National Interdisciplinary Innovation Team of Traditional Chinese Medicine(ZYYCXTD-D-202209).
文摘but its application is constrained by hepatotoxicity.This study aimed to investigate the feasibility of reducing AAEO’s toxicity through storage and to evaluate changes in chemical composition,toxicity,and bioactivity.Methods:Gas chromatography-mass spectrometry was used to analyze compositional changes during storage.Zebrafish acute toxicity tests and the liver-specific transgenic zebrafish model Tg(fabp10:EGFP)were used to assess toxicity.Antimicrobial,analgesic,and antioxidant assays evaluated variations in bioactivity.Results:Over the 150-day storage period,gas chromatography-mass spectrometry analysis identified 39 components.Zebrafish acute toxicity tests showed that the LD50 of AAEO stored for 0,30,60,90,120,and 150 days were 0.10μL·mL^(-1),0.10μL·mL^(-1),0.10μL·mL^(-1),0.11μL·mL^(-1),0.13μL·mL^(-1),and 0.14μL·mL^(-1),respectively,demonstrating a 40%reduction in acute toxicity after 150 days of storage.Using the liver-specific green fluorescent transgenic Tg(fabp10:EGFP)zebrafish model,the inhibition rates of AAEO on hepatic fluorescence intensity were measured at 68.5%,43.5%,42.6%,37.8%,34.6%,and 31.9% at different time points,confirming reduced hepatotoxicity after storage.Additionally,the antioxidant and analgesic activities of AAEO were significantly enhanced(p<0.05)after storage,while the antibacterial activity decreased(p<0.05).Conclusions:After storage,AAEO significantly reduces hepatotoxicity,with a 40% decrease in acute toxicity after 150 days.Meanwhile,the antioxidant and analgesic activities of AAEO increase,while its antibacterial activity decreases after storage.
基金financially supported by the National Key Research and Development Program of China(Grant No.2018YFB0104302)the National Natural Science Foundation of China(Grant No.51872026)。
文摘Recently,MnO2 has gained attention as an electrode material because of its very high theoretical capacity and abundant availability.However,the very high volumetric change caused by its conversion-type reaction results in bad reversibility of charge-discharge.In this study,δ-MnO2 of thickness 8 nm anchored on the surface of carbon nanotubes(CNT)by Mn-O-C chemical bonding is synthesized via a facile hydrothermal method.Numerous ex-situ characterizations of the lithium storage process were performed.Furthermore,density functional theory(DFT)calculations indicated thatδ-MnO2(012)thermodynamically prefers bonding with CNTs.Moreover,the interfacial interaction reinforces the connection of Mn-O and reduces the bond strength of Li-O in lithiated MnO2,which could facilitate an intercalation-type lithium storage reaction.Consequently,the as-synthesizedδ-MnO2 retains an excellent reversible capacity of 577.5 mAh g-1 in 1000 cycles at a high rate of 2 A g-1 between 0.1 V and 3.0 V.The results of this study demonstrate the possibility of employing the cost-effective transition metal oxides as intercalation lithium storage dominant electrodes for advanced rechargeable batteries.
基金funded by the Helmholtz Association of German Research Centersthe funding given by the German Federal Ministry for Economic Affairs and Energy to finance the research project METPORE Ⅱ (03ET2016)+2 种基金the METPORE Ⅱ project partnersSSC Strategic Science Consult GmbHBORSIG Membrane Technology GmbH
文摘Membrane gas separation is one of the most promising technologies for the separation of carbon dioxide （CO2） from various gas streams. One application of this technology is the treatment of flue gases from combustion processes for the purpose of carbon capture and storage. For this application, poly（ethylene oxide）-containing block copolymers such as Pebax or PolyActiveTM polymer are well suited. The thin-film composite membrane that is considered in this overview employs PolyActiveTM polymer as a selective layer material. The membrane shows excellent CO2 permeances of up to 4 m^3（STP）.（m^2·h·bar）^-1 （1 bar = 105 Pa） at a carbon dioxide/nitrogen （CO2/N2） selectivity exceeding 55 at ambient temperature. The membrane can be manufactured reproducibly on a pilot scale and mounted into fiat-sheet membrane modules of different designs. The operating performance of these modules can be accurately predicted by specifically developed simulation tools, which employ single-gas permeation data as the only experimental input. The performance of membranes and modules was investigated in different pilot plant studies, in which flue gas and biogas were used as the feed gas streams. The investigated processes showed a stable separation performance, indicating the applicability of PolyActiveTM polymer as a membrane material for industrialscale gas processing.
基金This work was supported by the National fuud for Fundamental Key Project(No.973G19990330) and theNational Natural Science Foundation of China(No.69977005).
文摘In this paper, a holographic storage scheme for multimedia data storage and retrieval based on the digital signal processing (DSP) is designed. A communication model for holographic storage system is obtained on the analogy of traditional communication system. Many characteristics of holographic storage are embodied in the communication model. Then some new methods of DSP including two-dimensional (2-D) shifting interleaving, encoding and decoding of modulation-array (MA) code and method of soft-decision, etc. are proposed and employed in the system. From the results of experiments it can be seen that those measures can effectively reduce the influence of noise. A segment of multimedia data, including video and audio data, is retrieved successfully after holographic storage by using those techniques.
基金the Mésocentre de calcul de Franche-Comte and on the TGCC(Très Grand Centre de Calcul du CEA)the HPC resources of TGCC under the allocations 2019-A0060910785 and 2020-A0080910785 provided by GENCI.
文摘The very wide applications of LTA zeolites,e.g.tritiated water storage,imply that a precise atomic-scale description of the adsorption processes taking place in their structure is crucial.The zeolite structure seems to have a catalytic effect on the O_(2)/H_(2)recombination during the storage process after water radiolysis.To look closely at the conditions that could bring O_(2)and H_(2)to this particular point,we have conducted investigations using static DFT and systematic ab initio molecular dynamics calculations.We have investigated the interaction of these two molecules with the sodium cations,on which the adsorption capacity of the Na-LTA zeolite depends.The O_(2)and H_(2)molecules’behaviour inside the cavities is linked to the Na+position and availability.The latter is regulated by the presence of H_(2)O which interacts with Na+in a stronger way than O_(2)and H_(2).Thus,the adsorption studies of different mixtures(O_(2)/H_(2)O,H_(2)/H_(2)O and H_(2)/O_(2))have been carried out to characterise the competition between water and other vip molecules.The absence of an obvious interaction between the adsorbates strongly suggests a potential reaction path involving the catalytic effect of the zeolite.Since we have been able to show that the behaviour of O_(2)and H_(2)molecules is directly affected by the water coverage rate,the reaction path is very likely to be affected too.These results mark a step towards the description of a recombination mechanism between O_(2)and H_(2)in a zeolite structure,a crucial issue for such systems involving tritiated water adsorbed in nanoporous materials.
基金supported by the 111 Project(No.111-2-06)Xining Science and Technology Planning Program(2023-Y-04).
文摘Daqu provides microbiota,flavor substances and enzymes for liquor fermentation.Storage after fermentation is an essential stage for the mature of Daqu.However,it is still unclear about the effect of storage on the microbiota structure and enzyme profile.Here,this work revealed the variation of microbiota structure and enzyme profile after storage of low-temperature Daqu using amplicon sequencing and proteomic profile analysis.Results showed that the content of acidity significantly increased by 13.79%(P<0.05).The saccharification power,liquefaction power and fermentation power significantly increased by 2.90%,17.32%and 16.04%,respectively(P<0.05).The contents of 3-methyl-1-butanol and 1-octen-3-ol increased by 147.19%and 29.12%,respectively(P<0.05).Lichtheimia,Saccharomyces,Rhizopus,Aspergillus,Pantoea,Lactiplantibacillus,Pichia,Lacticaseibacillus,Pseudo-monas,Linnemannia,Levilactobacillus,Pediococcus,Paenibacillus and Lactobacillus were the major enzyme-producing microbiota(average protein abundance>1%)using proteomic profile analysis.After storage,the relative abundances of Lactobacillus and Aspergillus increased from 2.59%to 17.63%,and 7.53%-33.67%using amplicon sequencing,respectively.The protein abundance of α-amylase produced by Aspergillus increased from 0.05%to 0.11%,and was consistent with variations of the relative abundance of Aspergillus,and the liquefaction power.The protein abundance of lactic acid dehydrogenase produced by Lactobacillus increased from 0.07%to 0.11%,and was consistent with the variation of relative abundance of Lactobacillus.This work revealed the effect of storage on microbioa and enzyme proteomic profile of low-temperature Daqu.It would be beneficial for controlling the storage stage of Daqu,and help improving the quality of Daqu.
基金supported by the National Natural Science Foundation of China(92261203,22101116 and 21971106)the Science Research Foundation of Jilin Province(YDZJ202301ZYTS478)+1 种基金Shenzhen Fundamental Research Program(JCYJ20220530115001002)the Stable Support Plan Program of Shenzhen Natural Science Fund(20200925161141006).
文摘Magneto-structural correlations are of great importance in developing single-molecule magnets(SMMs)for storage and quantum processing of information.In this work,three cyclooctatetraenylido(COT)ligands,namely COT^(TMS1),COT^(TMS2),and COT^(TMS3) equipped with one,two,and three trimethylsilyl(TMS)substituent(s),respectively,were used to prepare the corresponding Er(Ⅲ)complexes,namely[K(DME)_(2)][Er(COT^(TMS1))_(2)](1:DME,1,2-dimethoxyethane),[K(DME)_(2)][Er(COT^(TMS2))_(2)](2),and[K(18-crown-6)_(1.5)][Er(COT^(TMS3))_(2)](3).The complexes,each featuring an Er(Ⅲ)ion sandwiched by two cyclooctatetraenyl rings,possess uni-axial magnetic anisotropy and display single-molecule magnet behaviors with energy barriers of 208(1)K for 1,193(2)K for 2,and 217(18)K for 3,and blocking temperatures of 11,10,and 9 K,respectively.The relaxation times are found to be closely related to the number of TMS substituents,with that of 1 being about 10 times longer than that of 2,and more significantly,100 times longer than that of 3 at the same temperatures.Studies using infrared spectroscopy indicate that the molecular vibrations of the complexes intensify upon increasing the number of TMS substituents in the ligands,resulting in faster magnetic relaxation.Further analyses reveal that the molecular vibrations in these complexes are related to the pre-exponential factor τ_(0) for the Orbach process or C value for the Raman process.
基金supported in part by the Jilin Provincial Department of Science and Technology,China(YDZJ202303CGZH010)Jilin Provincial Department of Human Resources and Social Security,China(2022QN05)the Changchun Science and Technology Bureau,China(21ZGM29).
文摘With the process of medical informatization,medical diagnosis results are recorded and shared in the form of electronic data in the computer.However,the security of medical data storage cannot be effectively protected and the unsafe sharing of medical data among different institutions is still a hidden danger that cannot be underestimated.To solve the above problems,a secure storage and sharing model of private data based on blockchain technology and homomorphic encryption is constructed.Based on the idea of blockchain decentralization,the model maintains a reliable medical alliance chain system to ensure the safe transmission of data between different institutions;A privacy data encryption and computing protocol based on homomorphic encryption is constructed to ensure the safe transmission of medical data;Using its complete anonymity to ensure the Blockchain of medical data and patient identity privacy;A strict transaction control management mechanism of medical data based on Intelligent contract automatic execution of preset instructions is proposed.After security verification,compared with the traditional medical big data storage and sharing mode,the model has better security and sharing.
