The somatotopic representation of specific body parts is a well-established spatial organizational principle in the primary somatosensory and motor cortices.
The progress of modern industry has given rise to great requirements for network transmission latency and reliability in domains such as smart grid and intelligent driving.To address these challenges,the concept of Ti...The progress of modern industry has given rise to great requirements for network transmission latency and reliability in domains such as smart grid and intelligent driving.To address these challenges,the concept of Time-sensitive networking(TSN)is proposed by IEEE 802.1TSN working group.In order to achieve low latency,Cyclic queuing and forwarding(CQF)mechanism is introduced to schedule Timetriggered(TT)flows.In this paper,we construct a TSN model based on CQF and formulate the flow scheduling problem as an optimization problem aimed at maximizing the success rate of flow scheduling.The problem is tackled by a novel algorithm that makes full use of the characteristics and the relationship between the flows.Firstly,by K-means algorithm,the flows are initially partitioned into subsets based on their correlations.Subsequently,the flows within each subset are sorted by a new special criteria extracted from multiple features of flow.Finally,a flow offset selecting method based on load balance is used for resource mapping,so as to complete the process of flow scheduling.Experimental results demonstrate that the proposed algorithm exhibits significant advantages in terms of scheduling success rate and time efficiency.展开更多
According to the practical problems in eddy current sorting,the method and technology of eddy current hardness sorting based on LeastSquaresSupportVectorMachine(LS-SVM)are proposed based on the Xilinx Artix-7 FPGA in ...According to the practical problems in eddy current sorting,the method and technology of eddy current hardness sorting based on LeastSquaresSupportVectorMachine(LS-SVM)are proposed based on the Xilinx Artix-7 FPGA in this paper.The calculated sorting-hyperplane and designed sorting decision-making machine were used to sort different hardness of the vavles.The experimental results of the vavle sorting show that the sorting success rate can reach 100%under conditions that the number of test vavles is one quarter of the training vavles.The method and technology based on LS-SVM can solve the problems that the impedance feature value is nonlinear with the hardness value and variable sorting interval.It also proved that the LS-SVM algorithm has strong practical value in online eddy current sorting.展开更多
Under the background of increasingly scarce ore worldwide and increasingly fierce market competition,developing the mining industry could be strongly restricted.Intelligent ore sorting equipment not only improves ore ...Under the background of increasingly scarce ore worldwide and increasingly fierce market competition,developing the mining industry could be strongly restricted.Intelligent ore sorting equipment not only improves ore use and enhances the economic benefits of enterprises but also increases the ore grade and lessens the grinding cost and tailings production.However,long-term research on intelligent ore sorting equipment found that the factors affecting sorting efficiency mainly include ore information identification technology,equipment sorting actuator,and information processing algorithm.The high precision,strong anti-interference capability,and high speed of these factors guarantee the separation efficiency of intelligent ore sorting equipment.Color ore sorter,X-ray ore transmission sorter,dual-energy X-ray transmission ore sorter,X-ray fluorescence ore sorter,and near-infrared ore sorter have been successfully developed in accordance with the different characteristics of minerals while ensuring the accuracy of equipment sorting and improving the equipment sorting efficiency.With the continuous improvement of mine automation level,the application of online element rapid analysis technology with high speed,high precision,and strong anti-interference capability in intelligent ore sorting equipment will become an inevitable trend of equipment development in the future.Laser-induced breakdown spectroscopy,transientγneutron activation analysis,online Fourier transform infrared spectroscopy,and nuclear magnetic resonance techniques will promote the development of ore sorting equipment.In addition,the improvement and joint application of additional high-speed and high-precision operation algorithms(such as peak area,principal component analysis,artificial neural network,partial least squares,and Monte Carlo library least squares methods)are an essential part of the development of intelligent ore sorting equipment in the future.展开更多
Objective: In this paper we compared the two methods of cell sorting (magnetic cell sorting and flow cytometry sorting) for the isolation and function analysis of mouse CD4+ CD25+ regulatory T (Treg) cells, in order t...Objective: In this paper we compared the two methods of cell sorting (magnetic cell sorting and flow cytometry sorting) for the isolation and function analysis of mouse CD4+ CD25+ regulatory T (Treg) cells, in order to inform further studies in Treg cell function. Methods: We separately used magnetic cell sorting and flow cytometry sorting to identify CD4+ CD25+ Treg cells. After magnetic cell separation, we further used flow cytometry to analyze the purity of CD4+ CD25+ Treg cells, trypan blue staining to detect cell viability, and propidium iodide (PI) staining to assess the cell viability. We detected the immune inhibition of CD4+ CD25+ Treg cells in the in vitro proliferation experiments. Results: The results showed that compared to flow cytometry sorting, magnetic cell sorting took more time and effort, but fewer live cells were obtained than with flow cytometry sorting. The CD4+ CD25+ Treg cells, however, obtained with both methods have similar immunosuppressive capacities. Conclusion: The result suggests that both methods can be used in isolating CD4+ CD25+ Treg cells, and one can select the best method according to specific needs and availability of the methodologies.展开更多
Retromer is an evolutionarily conserved multimeric protein complex that mediates intracellular transport of various vesicular cargoes and functions in a wide variety of cellular processes including polarized trafficki...Retromer is an evolutionarily conserved multimeric protein complex that mediates intracellular transport of various vesicular cargoes and functions in a wide variety of cellular processes including polarized trafficking,developmental signaling and lysosome biogenesis.Through its interaction with the Rab GTPases and their effectors,membrane lipids,molecular motors,the endocytic machinery and actin nucleation promoting factors,retromer regulates sorting and trafficking of transmembrane proteins from endosomes to the trans-Golgi network（TGN） and the plasma membrane.In this review.I highlight recent progress in the understanding of relromer-medialed protein sorting and vesicle trafficking and discuss how retromer contributes to a diverse set of developmental,physiological and pathological processes.展开更多
Borda sorting algorithm is a kind of improvement algorithm based on weighted position sorting algorithm,it is mainly suitable for the high duplication of search results,for the independent search results,the effect is...Borda sorting algorithm is a kind of improvement algorithm based on weighted position sorting algorithm,it is mainly suitable for the high duplication of search results,for the independent search results,the effect is not very good and the computing method of relative score in Borda sorting algorithm is according to the rule of the linear regressive,but position relationship cannot fully represent the correlation changes.aimed at this drawback,the new sorting algorithm is proposed in this paper,named PMS-Sorting algorithm,firstly the position score of the returned results is standardized processing,and the similarity retrieval word string with the query results is combined into the algorithm,the similarity calculation method is also improved,through the experiment,the improved algorithm is superior to traditional sorting algorithm.展开更多
This paper provides a new sorting algorithm called 'Only-Once-Sorting' algorithm a mathemati cal formula,this algorithm can put elements in the positions they should be stored only once,then compacts them.The ...This paper provides a new sorting algorithm called 'Only-Once-Sorting' algorithm a mathemati cal formula,this algorithm can put elements in the positions they should be stored only once,then compacts them.The algorithm completes sorting a sequence of n elements in a calculation time of O(n ).展开更多
Several parallel sorting techniques on different architectures have been studied for many years. Due to the need for faster systems in today＇s world, parallelism can be used to accelerate applications. Nowadays, para...Several parallel sorting techniques on different architectures have been studied for many years. Due to the need for faster systems in today＇s world, parallelism can be used to accelerate applications. Nowadays, parallel operations are used to solve computer problems such as sort and search, which result in a reasonable speed. Sorting is one of the most important operations in computing world. The authors always try to find the best in different areas which the premier is speedup. In this paper, the authors issued a sort with O（logn） time complexity on PRAM EREW （Parallel Random Access Machine Exclusive Read Exclusive Write）. The algorithm is designed in a manner that keeps the tradeoff between the number of processor elements in the architecture and execution time. The simulation of the algorithm proves the theoretical analysis of the algorithm. The results of this research can be utilized in developing faster embedded systems. Sorting on Centralized Diamond （SOCD） algorithm is issued on the novel Centralized Diamond architecture which takes the advantages of Single Instruction Multiple Data （SIMD） architecture. This architecture and the sort on it are intuitive and optimal.展开更多
The non-dominated sorting genetic algorithm （NSGA） is improved with the controlled elitism and dynamic crowding distance. A novel multi-objective optimization algorithm is obtained for wind turbine blades. As an exa...The non-dominated sorting genetic algorithm （NSGA） is improved with the controlled elitism and dynamic crowding distance. A novel multi-objective optimization algorithm is obtained for wind turbine blades. As an example, a 5 MW wind turbine blade design is presented by taking the maximum power coefficient and the minimum blade mass as the optimization objectives. The optimal results show that this algorithm has good performance in handling the multi-objective optimization of wind turbines, and it gives a Pareto-optimal solution set rather than the optimum solutions to the conventional multi objective optimization problems. The wind turbine blade optimization method presented in this paper provides a new and general algorithm for the multi-objective optimization of wind turbines.展开更多
The main function of electronic support measure system is to detect threating signals in order to take countermeasures against them. To accomplish this objective, a process of associating each interleaved pulse with i...The main function of electronic support measure system is to detect threating signals in order to take countermeasures against them. To accomplish this objective, a process of associating each interleaved pulse with its emitter must be done. This process is termed sorting or de-interleaving. A novel point symmetry based radar sorting (PSBRS) algorithm is addressed. In order to deal with all kinds of radar signals, the symmetry measure distance is used to cluster pulses instead of the conventional Euclidean distance. The reference points of the symmetrical clusters are initialized by the alternative fuzzy c-means (AFCM) algorithm to ameliorate the effects of noise and the false sorting. Besides, the density filtering (DF) algorithm is proposed to discard the noise pulses or clutter. The performance of the algorithm is evaluated under the effects of noise and missing pulses. It has been observed that the PSBRS algorithm can cope with a large number of noise pulses and it is completely independent of missing pulses. Finally, PSBRS is compared with some benchmark algorithms, and the simulation results reveal the feasibility and efficiency of the algorithm.展开更多
The recycling of construction and demolition waste(CDW)remains an urgent problem to be solved.In the industry,raw CDW needs to be manually sorted.To achieve high efficiency and avoid the risks of manual sorting,a sort...The recycling of construction and demolition waste(CDW)remains an urgent problem to be solved.In the industry,raw CDW needs to be manually sorted.To achieve high efficiency and avoid the risks of manual sorting,a sorting robot can be designed to grasp and sort CDW on a conveyor belt.But dynamic grasping on the conveyor belt is a challenge.We collected location information with a three-dimensional camera and then evaluated the method of dynamic robotic grasping.This paper discusses the grasping strategy of rough processed CDW on the conveyor belt,and implements the function of grasping and sorting on the recycling line.Furthermore,two new mathematical models for a robotic locating system are established,the accuracy of the model is tested with Matlab,and the selected model is applied to actual working conditions to verify the sorting accuracy.Finally,the robot kinematics parameters are optimized to improve the sorting efficiency through experiments in a real system,and it was concluded that when the conveyor speed was kept at around 0.25 m/s,better sorting results could be achieved.Increasing the speed and shortening the acceleration/deceleration time would reach the maximum efficiency when the load would allow it.Currently,the sorting efficiency reached approximately 2000 pieces per hour,showing a high accuracy.展开更多
Sensor-based ore sorting is a technology used to classify high-grade mineralized rocks from low-grade waste rocks to reduce operation costs.Many ore-sorting algorithms using color images have been proposed in the past...Sensor-based ore sorting is a technology used to classify high-grade mineralized rocks from low-grade waste rocks to reduce operation costs.Many ore-sorting algorithms using color images have been proposed in the past,but only some validate their results using mineral grades or optimize the algorithms to classify rocks in real-time.This paper presents an ore-sorting algorithm based on image processing and machine learning that is able to classify rocks from a gold and silver mine based on their grade.The algorithm is composed of four main stages:(1)image segmentation and partition,(2)color and texture feature extraction,(3)sub-image classification using neural networks,and(4)a voting system to determine the overall class of the rock.The algorithm was trained using images of rocks that a geologist manually classified according to their mineral content and then was validated using a different set of rocks analyzed in a laboratory to determine their gold and silver grades.The proposed method achieved a Matthews correlation coefficient of 0.961 points,higher than other classification algorithms based on support vector machines and convolutional neural networks,and a processing time under 44 ms,promising for real-time ore sorting applications.展开更多
Incomplete lineage sorting and introgression are 2 major and nonexclusive causes of specieslevel non-monophyly.Distinguishing between these 2 processes is notoriously difficult because they can generate similar geneti...Incomplete lineage sorting and introgression are 2 major and nonexclusive causes of specieslevel non-monophyly.Distinguishing between these 2 processes is notoriously difficult because they can generate similar genetic signatures.Previous studies have suggested that 2 closely related duck species,the Chinese spot-billed duck Anas zonorhyncha and the mallard A.platyrhynchosvjere polyphyletically intermixed.Here,we utilized a wide geographical sampling,multilocus data and a coalescent-based model to revisit this system.Our study confirms the finding that Chinese spot-billed ducks and Mallards are not monophyletic.There was no apparent interspecific differentiation across loci except those at the mitochondrial DNA(mtDNA)control region and the Z chromosome(CHD1Z).Based on an isolation-with-migration model and the geographical distribution of lineages,we suggest that both introgression and incomplete lineage sorting might contribute to the observed non-monophyly of the 2 closely related duck species.The mtDNA introgression was asymmetric,with high gene flow from Chinese spot-billed ducks to Mallards and negligible gene flow in the opposite direction.Given that the 2 duck species are phenotypically distinctive but weakly genetically differentiated,future work based on genomescale data is necessary to uncover genomic regions that are involved in divergence,and this work may provide further insights into the evolutionary histories of the 2 species and other waterfowls.展开更多
A novel class of periodically changing features hidden in radar pulse sequence environment,named G features,is proposed.Combining fractal theory and Hilbert-Huang transform,the features are extracted using changing ch...A novel class of periodically changing features hidden in radar pulse sequence environment,named G features,is proposed.Combining fractal theory and Hilbert-Huang transform,the features are extracted using changing characteristics of pulse parameters in radar emitter signals.The features can be applied in modern complex electronic warfare environment to address the issue of signal sorting when radar emitter pulse signal parameters severely or even completely overlap.Experiment results show that the proposed feature class and feature extraction method can discriminate periodically changing pulse sequence signal sorting features from radar pulse signal flow with complex variant features,therefore provide a new methodology for signal sorting.展开更多
In order to solve discrete multi-objective optimization problems, a non-dominated sorting quantum particle swarm optimization (NSQPSO) based on non-dominated sorting and quantum particle swarm optimization is proposed...In order to solve discrete multi-objective optimization problems, a non-dominated sorting quantum particle swarm optimization (NSQPSO) based on non-dominated sorting and quantum particle swarm optimization is proposed, and the performance of the NSQPSO is evaluated through five classical benchmark functions. The quantum particle swarm optimization (QPSO) applies the quantum computing theory to particle swarm optimization, and thus has the advantages of both quantum computing theory and particle swarm optimization, so it has a faster convergence rate and a more accurate convergence value. Therefore, QPSO is used as the evolutionary method of the proposed NSQPSO. Also NSQPSO is used to solve cognitive radio spectrum allocation problem. The methods to complete spectrum allocation in previous literature only consider one objective, i.e. network utilization or fairness, but the proposed NSQPSO method, can consider both network utilization and fairness simultaneously through obtaining Pareto front solutions. Cognitive radio systems can select one solution from the Pareto front solutions according to the weight of network reward and fairness. If one weight is unit and the other is zero, then it becomes single objective optimization, so the proposed NSQPSO method has a much wider application range. The experimental research results show that the NSQPS can obtain the same non-dominated solutions as exhaustive search but takes much less time in small dimensions; while in large dimensions, where the problem cannot be solved by exhaustive search, the NSQPSO can still solve the problem, which proves the effectiveness of NSQPSO.展开更多
Through the transformation of hydraulic constraints into the objective functions associated with a water supply network rehabilitation problem, a non-dominated sorting Genetic Algorithm-II (NSGA-II) can be used to sol...Through the transformation of hydraulic constraints into the objective functions associated with a water supply network rehabilitation problem, a non-dominated sorting Genetic Algorithm-II (NSGA-II) can be used to solve the altered multi-objective optimization model. The introduction of NSGA-II into water supply network optimal rehabilitation problem solves the conflict between one fitness value of standard genetic algorithm (SGA) and multi-objectives of rehabilitation problem. And the uncertainties brought by using weight coefficients or punish functions in conventional methods are controlled. And also by in-troduction of artificial inducement mutation (AIM) operation, the convergence speed of population is accelerated;this operation not only improves the convergence speed, but also improves the rationality and feasibility of solutions.展开更多
Common sorting method have low sorting rates and is sensitive to the Signal-to-Noise Ratio(SNR),wavelet characteristics of Wigner-Ville distribution are applied to sort unknown complicated radar signal,high sorting ac...Common sorting method have low sorting rates and is sensitive to the Signal-to-Noise Ratio(SNR),wavelet characteristics of Wigner-Ville distribution are applied to sort unknown complicated radar signal,high sorting accuracy can be got.The Wigner-Ville distribution of received signal is calculated,then it is predigested to two-dimensional characteristics.Using wavelet transformation to extract characteristics from two-dimensional of Wigner-Ville distribution,the best characteristics are selected to be used as sorting parameters.Experiment results demonstrated that the characteristics of eight typical radar emitter signals extracted by this method showed good performance of noise-resistance and clustering at large-scale SNR.展开更多
BACKGROUND Increasing evidence have shown that regional lymph node metastasis is a critical prognostic factor in gastric cancer(GC).In addition,lymph node dissection is a key factor in determining the appropriate trea...BACKGROUND Increasing evidence have shown that regional lymph node metastasis is a critical prognostic factor in gastric cancer(GC).In addition,lymph node dissection is a key factor in determining the appropriate treatment for GC.However,the association between the number of positive lymph nodes and area of lymph node metastasis in GC remains unclear.AIM To investigate the clinical value of regional lymph node sorting after radical gastrectomy for GC.METHODS This study included 661 patients with GC who underwent radical gastrectomy at Tianjin Medical University General Hospital between January 2012 and June 2020.The patients were divided into regional sorting and non-sorting groups.Clinicopathological data were collected and retrospectively reviewed to determine the differences in the total number of lymph nodes and number of positive lymph nodes between the groups.Independent sample t-tests were used for intergroup comparisons.Continuous variables that did not conform to a normal distribution were expressed as median(interquartile range),and the Mann-Whitney U test was used for inter-group comparisons.RESULTS There were no significant differences between the groups in terms of the surgical method,tumor site,immersion depth,and degree of differentiation.The total number of lymph nodes was significantly higher in the regional sorting group(n=324)than in the non-sorting group(n=337)(32.5 vs 21.2,P<0.001).There was no significant difference in the number of positive lymph nodes between the two groups.A total of 212 patients with GC had lymph node metastasis in the lymph node regional sorting group,including 89(41.98%)cases in the first dissection station and 123(58.02%)cases in the second dissection station.Binary and multivariate logistic regression results showed that the number of positive lymph nodes(P<0.001)was an independent risk factor for lymph node metastases at the second dissection station.CONCLUSION Regional sorting of lymph nodes after radical gastrectomy may increase the number of detected lymph nodes,thereby improving the reliability and accuracy of lymph node staging in clinical practice.展开更多
The deterministic lateral displacement (DLD) is an important method used to sort particles and cells of different sizes. In this paper, the flexible cell sorting with the DLD method is studied by using a numerical mod...The deterministic lateral displacement (DLD) is an important method used to sort particles and cells of different sizes. In this paper, the flexible cell sorting with the DLD method is studied by using a numerical model based on the immersed boundary-lattice Boltzmann method (IB-LBM). In this model, the fluid motion is solved by the LBM, and the cell membrane-fluid interaction is modeled with the LBM. The proposed model is validated by simulating the rigid particle sorted with the DLD method, and the results are found in good agreement with those measured in experiments. We first study the effect of flexibility on a single cell and multiple cells continuously going through a DLD device. It is found that the cell flexibility can significantly affect the cell path, which means the flexibility could have significant effects on the continuous cell sorting by the DLD method. The sorting characteristics of white blood cells and red blood cells are further studied by varying the spatial distribution of cylinder arrays and the initial cell-cell distance. The numerical results indicate that a well concentrated cell sorting can be obtained under a proper arrangement of cylinder arrays and a large enough initial cell-cell distance.展开更多
文摘The somatotopic representation of specific body parts is a well-established spatial organizational principle in the primary somatosensory and motor cortices.
基金supported by Science and Technology Project of State Grid Corporation Headquarters under Grant 5108-202218280A-2-170-XG(Development and Application of Power Time-Sensitive Network Switching Chip。
文摘The progress of modern industry has given rise to great requirements for network transmission latency and reliability in domains such as smart grid and intelligent driving.To address these challenges,the concept of Time-sensitive networking(TSN)is proposed by IEEE 802.1TSN working group.In order to achieve low latency,Cyclic queuing and forwarding(CQF)mechanism is introduced to schedule Timetriggered(TT)flows.In this paper,we construct a TSN model based on CQF and formulate the flow scheduling problem as an optimization problem aimed at maximizing the success rate of flow scheduling.The problem is tackled by a novel algorithm that makes full use of the characteristics and the relationship between the flows.Firstly,by K-means algorithm,the flows are initially partitioned into subsets based on their correlations.Subsequently,the flows within each subset are sorted by a new special criteria extracted from multiple features of flow.Finally,a flow offset selecting method based on load balance is used for resource mapping,so as to complete the process of flow scheduling.Experimental results demonstrate that the proposed algorithm exhibits significant advantages in terms of scheduling success rate and time efficiency.
基金supported by a project of the National Natural Science Foundation(No.51865004)the Guizhou Science and Technology Department(No.QKH20161081,No.QKH20192881)
文摘According to the practical problems in eddy current sorting,the method and technology of eddy current hardness sorting based on LeastSquaresSupportVectorMachine(LS-SVM)are proposed based on the Xilinx Artix-7 FPGA in this paper.The calculated sorting-hyperplane and designed sorting decision-making machine were used to sort different hardness of the vavles.The experimental results of the vavle sorting show that the sorting success rate can reach 100%under conditions that the number of test vavles is one quarter of the training vavles.The method and technology based on LS-SVM can solve the problems that the impedance feature value is nonlinear with the hardness value and variable sorting interval.It also proved that the LS-SVM algorithm has strong practical value in online eddy current sorting.
基金supported by the National Science and Technology Support Program of China(No.2012BAC11B07)the Jiangxi Science and Technology Innovation Base Plan(No.20212BCD42017)。
文摘Under the background of increasingly scarce ore worldwide and increasingly fierce market competition,developing the mining industry could be strongly restricted.Intelligent ore sorting equipment not only improves ore use and enhances the economic benefits of enterprises but also increases the ore grade and lessens the grinding cost and tailings production.However,long-term research on intelligent ore sorting equipment found that the factors affecting sorting efficiency mainly include ore information identification technology,equipment sorting actuator,and information processing algorithm.The high precision,strong anti-interference capability,and high speed of these factors guarantee the separation efficiency of intelligent ore sorting equipment.Color ore sorter,X-ray ore transmission sorter,dual-energy X-ray transmission ore sorter,X-ray fluorescence ore sorter,and near-infrared ore sorter have been successfully developed in accordance with the different characteristics of minerals while ensuring the accuracy of equipment sorting and improving the equipment sorting efficiency.With the continuous improvement of mine automation level,the application of online element rapid analysis technology with high speed,high precision,and strong anti-interference capability in intelligent ore sorting equipment will become an inevitable trend of equipment development in the future.Laser-induced breakdown spectroscopy,transientγneutron activation analysis,online Fourier transform infrared spectroscopy,and nuclear magnetic resonance techniques will promote the development of ore sorting equipment.In addition,the improvement and joint application of additional high-speed and high-precision operation algorithms(such as peak area,principal component analysis,artificial neural network,partial least squares,and Monte Carlo library least squares methods)are an essential part of the development of intelligent ore sorting equipment in the future.
基金Project supported by the National Natural Science Foundation of China (Nos. 30872578 and 30753761)the Natural Science Founda-tion of Shanxi Province (No. SJ08C201)+1 种基金the Science and Technology Key Projects Foundation of Shanxi Province (No. 2008K13-04)the Science and Technology Plan Projects Foundation of Xi’an (No. SF08006-2), China
文摘Objective: In this paper we compared the two methods of cell sorting (magnetic cell sorting and flow cytometry sorting) for the isolation and function analysis of mouse CD4+ CD25+ regulatory T (Treg) cells, in order to inform further studies in Treg cell function. Methods: We separately used magnetic cell sorting and flow cytometry sorting to identify CD4+ CD25+ Treg cells. After magnetic cell separation, we further used flow cytometry to analyze the purity of CD4+ CD25+ Treg cells, trypan blue staining to detect cell viability, and propidium iodide (PI) staining to assess the cell viability. We detected the immune inhibition of CD4+ CD25+ Treg cells in the in vitro proliferation experiments. Results: The results showed that compared to flow cytometry sorting, magnetic cell sorting took more time and effort, but fewer live cells were obtained than with flow cytometry sorting. The CD4+ CD25+ Treg cells, however, obtained with both methods have similar immunosuppressive capacities. Conclusion: The result suggests that both methods can be used in isolating CD4+ CD25+ Treg cells, and one can select the best method according to specific needs and availability of the methodologies.
基金supported by the National Natural Science Foundation of China(Nos.31325017,31471334 and 31530039)the National Basic Research Program(No.2014CB942802)
文摘Retromer is an evolutionarily conserved multimeric protein complex that mediates intracellular transport of various vesicular cargoes and functions in a wide variety of cellular processes including polarized trafficking,developmental signaling and lysosome biogenesis.Through its interaction with the Rab GTPases and their effectors,membrane lipids,molecular motors,the endocytic machinery and actin nucleation promoting factors,retromer regulates sorting and trafficking of transmembrane proteins from endosomes to the trans-Golgi network（TGN） and the plasma membrane.In this review.I highlight recent progress in the understanding of relromer-medialed protein sorting and vesicle trafficking and discuss how retromer contributes to a diverse set of developmental,physiological and pathological processes.
基金This work was funded by the National Natural Science Foundation of China under Grant(No.61772152 and No.61502037)the Basic Research Project(Nos.JCKY2016206B001,JCKY2014206C002 and JCKY2017604C010)the Technical Foundation Project(No.JSQB2017206C002).
文摘Borda sorting algorithm is a kind of improvement algorithm based on weighted position sorting algorithm,it is mainly suitable for the high duplication of search results,for the independent search results,the effect is not very good and the computing method of relative score in Borda sorting algorithm is according to the rule of the linear regressive,but position relationship cannot fully represent the correlation changes.aimed at this drawback,the new sorting algorithm is proposed in this paper,named PMS-Sorting algorithm,firstly the position score of the returned results is standardized processing,and the similarity retrieval word string with the query results is combined into the algorithm,the similarity calculation method is also improved,through the experiment,the improved algorithm is superior to traditional sorting algorithm.
文摘This paper provides a new sorting algorithm called 'Only-Once-Sorting' algorithm a mathemati cal formula,this algorithm can put elements in the positions they should be stored only once,then compacts them.The algorithm completes sorting a sequence of n elements in a calculation time of O(n ).
文摘Several parallel sorting techniques on different architectures have been studied for many years. Due to the need for faster systems in today＇s world, parallelism can be used to accelerate applications. Nowadays, parallel operations are used to solve computer problems such as sort and search, which result in a reasonable speed. Sorting is one of the most important operations in computing world. The authors always try to find the best in different areas which the premier is speedup. In this paper, the authors issued a sort with O（logn） time complexity on PRAM EREW （Parallel Random Access Machine Exclusive Read Exclusive Write）. The algorithm is designed in a manner that keeps the tradeoff between the number of processor elements in the architecture and execution time. The simulation of the algorithm proves the theoretical analysis of the algorithm. The results of this research can be utilized in developing faster embedded systems. Sorting on Centralized Diamond （SOCD） algorithm is issued on the novel Centralized Diamond architecture which takes the advantages of Single Instruction Multiple Data （SIMD） architecture. This architecture and the sort on it are intuitive and optimal.
基金Project supported by the National Basic Research Program of China (973 Program) (No. 2007CB714600)
文摘The non-dominated sorting genetic algorithm （NSGA） is improved with the controlled elitism and dynamic crowding distance. A novel multi-objective optimization algorithm is obtained for wind turbine blades. As an example, a 5 MW wind turbine blade design is presented by taking the maximum power coefficient and the minimum blade mass as the optimization objectives. The optimal results show that this algorithm has good performance in handling the multi-objective optimization of wind turbines, and it gives a Pareto-optimal solution set rather than the optimum solutions to the conventional multi objective optimization problems. The wind turbine blade optimization method presented in this paper provides a new and general algorithm for the multi-objective optimization of wind turbines.
基金supported by the National Natural Science Foundation of China(61172116)
文摘The main function of electronic support measure system is to detect threating signals in order to take countermeasures against them. To accomplish this objective, a process of associating each interleaved pulse with its emitter must be done. This process is termed sorting or de-interleaving. A novel point symmetry based radar sorting (PSBRS) algorithm is addressed. In order to deal with all kinds of radar signals, the symmetry measure distance is used to cluster pulses instead of the conventional Euclidean distance. The reference points of the symmetrical clusters are initialized by the alternative fuzzy c-means (AFCM) algorithm to ameliorate the effects of noise and the false sorting. Besides, the density filtering (DF) algorithm is proposed to discard the noise pulses or clutter. The performance of the algorithm is evaluated under the effects of noise and missing pulses. It has been observed that the PSBRS algorithm can cope with a large number of noise pulses and it is completely independent of missing pulses. Finally, PSBRS is compared with some benchmark algorithms, and the simulation results reveal the feasibility and efficiency of the algorithm.
基金The authors are thankful for the financial support provided by the Science and Technology Project of Quanzhou(Nos.2018C100R and 2019G003)the Science and Technology Cooperation Program of Quanzhou(No.2018C001)+1 种基金the Science and Technology Cooperation Program of Fujian(No.2018I1006)the Joint Innovation Project of Industrial Technology in the Fujian Province,and Subsidized Project for Postgraduates′Innovative Fund in Scientific Research of Huaqiao University.
文摘The recycling of construction and demolition waste(CDW)remains an urgent problem to be solved.In the industry,raw CDW needs to be manually sorted.To achieve high efficiency and avoid the risks of manual sorting,a sorting robot can be designed to grasp and sort CDW on a conveyor belt.But dynamic grasping on the conveyor belt is a challenge.We collected location information with a three-dimensional camera and then evaluated the method of dynamic robotic grasping.This paper discusses the grasping strategy of rough processed CDW on the conveyor belt,and implements the function of grasping and sorting on the recycling line.Furthermore,two new mathematical models for a robotic locating system are established,the accuracy of the model is tested with Matlab,and the selected model is applied to actual working conditions to verify the sorting accuracy.Finally,the robot kinematics parameters are optimized to improve the sorting efficiency through experiments in a real system,and it was concluded that when the conveyor speed was kept at around 0.25 m/s,better sorting results could be achieved.Increasing the speed and shortening the acceleration/deceleration time would reach the maximum efficiency when the load would allow it.Currently,the sorting efficiency reached approximately 2000 pieces per hour,showing a high accuracy.
文摘Sensor-based ore sorting is a technology used to classify high-grade mineralized rocks from low-grade waste rocks to reduce operation costs.Many ore-sorting algorithms using color images have been proposed in the past,but only some validate their results using mineral grades or optimize the algorithms to classify rocks in real-time.This paper presents an ore-sorting algorithm based on image processing and machine learning that is able to classify rocks from a gold and silver mine based on their grade.The algorithm is composed of four main stages:(1)image segmentation and partition,(2)color and texture feature extraction,(3)sub-image classification using neural networks,and(4)a voting system to determine the overall class of the rock.The algorithm was trained using images of rocks that a geologist manually classified according to their mineral content and then was validated using a different set of rocks analyzed in a laboratory to determine their gold and silver grades.The proposed method achieved a Matthews correlation coefficient of 0.961 points,higher than other classification algorithms based on support vector machines and convolutional neural networks,and a processing time under 44 ms,promising for real-time ore sorting applications.
基金the National Natural Science Foundation of China(No.31401969,31772480)the Natural Science Foundation of Jiangxi Province(No.20161BAB214158).
文摘Incomplete lineage sorting and introgression are 2 major and nonexclusive causes of specieslevel non-monophyly.Distinguishing between these 2 processes is notoriously difficult because they can generate similar genetic signatures.Previous studies have suggested that 2 closely related duck species,the Chinese spot-billed duck Anas zonorhyncha and the mallard A.platyrhynchosvjere polyphyletically intermixed.Here,we utilized a wide geographical sampling,multilocus data and a coalescent-based model to revisit this system.Our study confirms the finding that Chinese spot-billed ducks and Mallards are not monophyletic.There was no apparent interspecific differentiation across loci except those at the mitochondrial DNA(mtDNA)control region and the Z chromosome(CHD1Z).Based on an isolation-with-migration model and the geographical distribution of lineages,we suggest that both introgression and incomplete lineage sorting might contribute to the observed non-monophyly of the 2 closely related duck species.The mtDNA introgression was asymmetric,with high gene flow from Chinese spot-billed ducks to Mallards and negligible gene flow in the opposite direction.Given that the 2 duck species are phenotypically distinctive but weakly genetically differentiated,future work based on genomescale data is necessary to uncover genomic regions that are involved in divergence,and this work may provide further insights into the evolutionary histories of the 2 species and other waterfowls.
基金supported by the National Natural Science Foundation of China (60872108)the Postdoctoral Science Foundation of China(200902411+3 种基金20080430903)Heilongjiang Postdoctoral Financial Assistance (LBH-Z08129)the Scientific and Technological Creative Talents Special Research Foundation of Harbin Municipality (2008RFQXG030)Central University Basic Research Professional Expenses Special Fund Project
文摘A novel class of periodically changing features hidden in radar pulse sequence environment,named G features,is proposed.Combining fractal theory and Hilbert-Huang transform,the features are extracted using changing characteristics of pulse parameters in radar emitter signals.The features can be applied in modern complex electronic warfare environment to address the issue of signal sorting when radar emitter pulse signal parameters severely or even completely overlap.Experiment results show that the proposed feature class and feature extraction method can discriminate periodically changing pulse sequence signal sorting features from radar pulse signal flow with complex variant features,therefore provide a new methodology for signal sorting.
基金Foundation item： Projects（61102106, 61102105） supported by the National Natural Science Foundation of China Project（2013M530148） supported by China Postdoctoral Science Foundation Project（HEUCF120806） supported by the Fundamental Research Funds for the Central Universities of China
文摘In order to solve discrete multi-objective optimization problems, a non-dominated sorting quantum particle swarm optimization (NSQPSO) based on non-dominated sorting and quantum particle swarm optimization is proposed, and the performance of the NSQPSO is evaluated through five classical benchmark functions. The quantum particle swarm optimization (QPSO) applies the quantum computing theory to particle swarm optimization, and thus has the advantages of both quantum computing theory and particle swarm optimization, so it has a faster convergence rate and a more accurate convergence value. Therefore, QPSO is used as the evolutionary method of the proposed NSQPSO. Also NSQPSO is used to solve cognitive radio spectrum allocation problem. The methods to complete spectrum allocation in previous literature only consider one objective, i.e. network utilization or fairness, but the proposed NSQPSO method, can consider both network utilization and fairness simultaneously through obtaining Pareto front solutions. Cognitive radio systems can select one solution from the Pareto front solutions according to the weight of network reward and fairness. If one weight is unit and the other is zero, then it becomes single objective optimization, so the proposed NSQPSO method has a much wider application range. The experimental research results show that the NSQPS can obtain the same non-dominated solutions as exhaustive search but takes much less time in small dimensions; while in large dimensions, where the problem cannot be solved by exhaustive search, the NSQPSO can still solve the problem, which proves the effectiveness of NSQPSO.
基金the Natural Science Key Foundation of Heilongjiang Province of China (No. ZJG0503) China-UK Sci-ence Network from Royal Society UK
文摘Through the transformation of hydraulic constraints into the objective functions associated with a water supply network rehabilitation problem, a non-dominated sorting Genetic Algorithm-II (NSGA-II) can be used to solve the altered multi-objective optimization model. The introduction of NSGA-II into water supply network optimal rehabilitation problem solves the conflict between one fitness value of standard genetic algorithm (SGA) and multi-objectives of rehabilitation problem. And the uncertainties brought by using weight coefficients or punish functions in conventional methods are controlled. And also by in-troduction of artificial inducement mutation (AIM) operation, the convergence speed of population is accelerated;this operation not only improves the convergence speed, but also improves the rationality and feasibility of solutions.
基金Supported by the National Science and Technology Supported Program of China(No.2011BAH24B05)
文摘Common sorting method have low sorting rates and is sensitive to the Signal-to-Noise Ratio(SNR),wavelet characteristics of Wigner-Ville distribution are applied to sort unknown complicated radar signal,high sorting accuracy can be got.The Wigner-Ville distribution of received signal is calculated,then it is predigested to two-dimensional characteristics.Using wavelet transformation to extract characteristics from two-dimensional of Wigner-Ville distribution,the best characteristics are selected to be used as sorting parameters.Experiment results demonstrated that the characteristics of eight typical radar emitter signals extracted by this method showed good performance of noise-resistance and clustering at large-scale SNR.
基金the Fundamental Scientific Research Project of Tianjin Universities of China,No.2017KJ191.
文摘BACKGROUND Increasing evidence have shown that regional lymph node metastasis is a critical prognostic factor in gastric cancer(GC).In addition,lymph node dissection is a key factor in determining the appropriate treatment for GC.However,the association between the number of positive lymph nodes and area of lymph node metastasis in GC remains unclear.AIM To investigate the clinical value of regional lymph node sorting after radical gastrectomy for GC.METHODS This study included 661 patients with GC who underwent radical gastrectomy at Tianjin Medical University General Hospital between January 2012 and June 2020.The patients were divided into regional sorting and non-sorting groups.Clinicopathological data were collected and retrospectively reviewed to determine the differences in the total number of lymph nodes and number of positive lymph nodes between the groups.Independent sample t-tests were used for intergroup comparisons.Continuous variables that did not conform to a normal distribution were expressed as median(interquartile range),and the Mann-Whitney U test was used for inter-group comparisons.RESULTS There were no significant differences between the groups in terms of the surgical method,tumor site,immersion depth,and degree of differentiation.The total number of lymph nodes was significantly higher in the regional sorting group(n=324)than in the non-sorting group(n=337)(32.5 vs 21.2,P<0.001).There was no significant difference in the number of positive lymph nodes between the two groups.A total of 212 patients with GC had lymph node metastasis in the lymph node regional sorting group,including 89(41.98%)cases in the first dissection station and 123(58.02%)cases in the second dissection station.Binary and multivariate logistic regression results showed that the number of positive lymph nodes(P<0.001)was an independent risk factor for lymph node metastases at the second dissection station.CONCLUSION Regional sorting of lymph nodes after radical gastrectomy may increase the number of detected lymph nodes,thereby improving the reliability and accuracy of lymph node staging in clinical practice.
基金supported by the National Natural Science Foundation of China (Grant 81301291)the Beijing Higher Education Young Elite Teacher Project (Grant YETP1208)UNSW Special Research Grants Program
文摘The deterministic lateral displacement (DLD) is an important method used to sort particles and cells of different sizes. In this paper, the flexible cell sorting with the DLD method is studied by using a numerical model based on the immersed boundary-lattice Boltzmann method (IB-LBM). In this model, the fluid motion is solved by the LBM, and the cell membrane-fluid interaction is modeled with the LBM. The proposed model is validated by simulating the rigid particle sorted with the DLD method, and the results are found in good agreement with those measured in experiments. We first study the effect of flexibility on a single cell and multiple cells continuously going through a DLD device. It is found that the cell flexibility can significantly affect the cell path, which means the flexibility could have significant effects on the continuous cell sorting by the DLD method. The sorting characteristics of white blood cells and red blood cells are further studied by varying the spatial distribution of cylinder arrays and the initial cell-cell distance. The numerical results indicate that a well concentrated cell sorting can be obtained under a proper arrangement of cylinder arrays and a large enough initial cell-cell distance.
