目的探究Sofia远端导管直接抽吸与支架取栓用于急性脑梗死的临床疗效。方法回顾性分析2022年6月至2023年3月乐平市人民医院收治的60例急性脑梗死患者的临床资料,按照治疗方式的不同分为抽吸组(n=35)和支架组(n=25)。抽吸组采用Sofia远...目的探究Sofia远端导管直接抽吸与支架取栓用于急性脑梗死的临床疗效。方法回顾性分析2022年6月至2023年3月乐平市人民医院收治的60例急性脑梗死患者的临床资料,按照治疗方式的不同分为抽吸组(n=35)和支架组(n=25)。抽吸组采用Sofia远端导管直接抽吸治疗,支架组采用支架取栓治疗。比较两组围手术期指标、手术相关并发症发生率、术后血管再通改良脑梗死溶栓血流分级(modified thrombolysis in cerebral infarction scale,mTICI)、美国国立卫生研究所卒中量表(National Institutes of Health stroke scale,NIHSS)评分、血清炎症因子[超敏C反应蛋白(hypersensitive C reactive protein,hs-CRP)、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)]水平以及改良Rankin量表(modified Rankin scale,mRS)评分和日常生活能力量表(activities of daily living scale,ADL)评分。结果抽吸组穿刺-血管成功再通时间短于支架组,取栓次数多于支架组,差异有统计学意义(P<0.05);两组住院时间比较差异无统计学意义。两组手术相关并发症发生率比较差异无统计学意义。抽吸组血管再通分级优于支架组,差异有统计学意义(P<0.05)。术后24 h、7 d,抽吸组NIHSS评分及hs-CRP、TNF-α水平均低于支架组,差异有统计学意义(P<0.05)。术后24 h,两组mRS、ADL评分比较差异无统计学意义;术后7、90 d,抽吸组mRS评分均低于支架组,ADL评分均高于支架组,差异有统计学意义(P<0.05)。结论与支架取栓相比,采用Sofia远端导管抽吸治疗急性脑梗死患者,血管再通时间更短,闭塞血管再通成功率更高,能有效改善患者神经功能、日常生活能力及炎症反应,利于预后,且安全性相当,值得临床推广应用。展开更多
目的评估SOFIA远端通路导管直接抽吸治疗早期急性缺血性脑卒中(acute ischemic stroke,AIS)的安全性及有效性。方法选取2018年1月至2019年10月间进行血管内治疗的早期AIS患者65例,其中20例首选SOFIA远端通路导管抽吸取栓治疗(抽吸组),4...目的评估SOFIA远端通路导管直接抽吸治疗早期急性缺血性脑卒中(acute ischemic stroke,AIS)的安全性及有效性。方法选取2018年1月至2019年10月间进行血管内治疗的早期AIS患者65例,其中20例首选SOFIA远端通路导管抽吸取栓治疗(抽吸组),45例首选支架取栓治疗(支架组)。采用改良脑梗死溶栓治疗分级(modified treatment in cerebral ischemia,mTICI)、美国国立卫生研究院卒中量表(National Institute of Health stroke scale,NIHSS)、改良Rankin量表评分(modified rankin scale,mRS)分别评估成功再通及临床预后。对比抽吸组与支架组的手术相关指标(手术时间、血管成功再通)、并发症及临床预后。结果抽吸组较支架组穿刺至血管成功再通时间短,差异具有统计学意义[27(14,36)min vs.34(29,50)min,P<0.05],而血管成功再通率(mTICI 2b/3级)差异无统计学意义(18/20 vs.38/45,P>0.05)。抽吸组与支架组发生血栓逃逸(1/20 vs.3/45)、颅内出血(3/20 vs.7/45)和其他不良事件(1/20 vs.5/45),差异无统计学意义(P>0.05)。抽吸组与支架组术后24 h和7 d NIHSS评分[10(5,13)vs.12(7,17),5(3,11)vs.10(3,15)],90 d mRS评分≤2分及死亡率,差异均无统计学意义(P>0.05)。结论与首选支架取栓相比,SOFIA远端通路导管直接抽吸治疗早期AIS患者具有相似安全性及疗效,且具有操作简单用时短的特点。展开更多
The Chinese Proficiency Test(HSK)is a standardized test on Chinese language skills which has been widely introduced both in and outside China and has been playing an important role in the spread of Chinese learning al...The Chinese Proficiency Test(HSK)is a standardized test on Chinese language skills which has been widely introduced both in and outside China and has been playing an important role in the spread of Chinese learning all over the world.In 2003 Bulgaria hosted a beginner level HSK exam,which made it the first location to hold a Chinese language proficiency test on the Balkan Peninsula and ever since it has been very successful.The current paper provides a research on the current state of the Chinese Proficiency Test(HSK)аt the Confucius Institute in Sofia,Bulgaria,analyzes the factors related to the promotion of the Chinese Proficiency Test(HSK)and on this basis presents a few feasible recommendations to the benefit of the Chinese Proficiency Test(HSK).展开更多
Objective: to investigate the therapeutic effect of Sofia catheter thrombectomy in elderly patients with acute ischemic stroke. Methods 22: elderly patients with acute ischemic stroke who underwent Sofia catheter thro...Objective: to investigate the therapeutic effect of Sofia catheter thrombectomy in elderly patients with acute ischemic stroke. Methods 22: elderly patients with acute ischemic stroke who underwent Sofia catheter thrombectomy (or) combined with stenting in Beijing Chaoyang integrated traditional Chinese and Western medicine emergency rescue center from January 2021 to December 2021 were analyzed retrospectively, including 8 cases of simple Sofia aspiration and 14 cases of combined stent thrombectomy. The general data, clinical characteristics and imaging manifestations of patients were analyzed. The improved thrombolytic test standard for cerebral infarction (mtici) was used to evaluate the patency of blood vessels. Grade 0-2a was occluded, and grade 2b-3 was successful recanalization;The National Institutes of health neurological deficit score (NIHSS) and the modified Rankin score (MRS) were evaluated before and after operation. Results: among the 22 elderly patients, there were 7 male patients and 15 female patients;The patients were 81-94 years old, with an average age of 84.45 ± 3.32 years. The Glasgow Coma Scale (GCS) score before admission was 4-10, with an average score of 7.95 ± 2.40.The blocked sites were basilar artery in 2 cases, bilateral posterior cerebral artery in 1 case, bilateral internal carotid artery in 1 case, right middle cerebral artery in 1 case, right internal carotid artery in 7 cases, left middle cerebral artery in 7 cases and left internal carotid artery in 3 cases. Preoperative intravenous thrombolysis was performed in 9 patients.22 elderly patients were rated by mtici after treatment. It can be seen that there were 2 patients with grade 2A (9.09%), 6 patients with grade 2B (27.27%) and 14 patients with grade 3 (63.64%).There was no significant difference in NIHSS score between patients after treatment and before treatment (18.18 ± 6.82 vs. 18.77 ± 5.98, P > 0.05).Among the 22 patients, 13 (59.09%) died due to complications or family members giving up rescue. Conclusion: Sofia catheter thrombectomy can effectively improve vascular occlusion, but it should be used with clinical caution in elderly patients.展开更多
The film The Color Purple mainly talks about the bitter situation of oppression and discrimination of American black wom-en through the life of protagonist Celie, and Celie’s spiritual journey of becoming awaken grad...The film The Color Purple mainly talks about the bitter situation of oppression and discrimination of American black wom-en through the life of protagonist Celie, and Celie’s spiritual journey of becoming awaken gradually and independent, and at last gain her own new life. Another black woman Sofia in the film has confidence, independence and fighting spirit. This paper will analyzes Sofia’s three personalities from the perspective of Freudian psychoanalysis, especially his theory of personality which divides the psyche into the id, the self, and the superego so as to better understand black wom-en’inner world in the oppression and discrimination society.展开更多
The effects of Lactobacillus johnsonii(L. johnsonii) on gut microflora, bird performance and intestinal development were assessed using 288 one-day-old Cobb broilers challenged with Salmonella sofia(S.sofia). The expe...The effects of Lactobacillus johnsonii(L. johnsonii) on gut microflora, bird performance and intestinal development were assessed using 288 one-day-old Cobb broilers challenged with Salmonella sofia(S.sofia). The experiment was a 3×2 factorial design which consisted of three treatments, a negative control(NC) with no additives, a positive control(PC) containing antimicrobials(zinc-bacitracin, 50 mg/kg) and a probiotic group(Pro), and with the two factors being unchallenged or challenged with S. sofia.A probiotic preparation of L. johnsonii(10~9 cfu/chick) was administered to chicks individually by oral gavage on days 1, 3, 7 and 12. Chicks were individually challenged with S. sofia(10~7 cfu/chick) by oral gavage on d 2, 8 and 13. Results showed that the challenge itself markedly reduced(P < 0.05) bird performance and feed intake. And, transient clinical symptoms of the infection with S. sofia were observed from the second time they were challenged with S. sofia in the negative challenge groups. The novel probiotic candidate L. johnsonii reduced the number of S. sofia and Clostridium perfringens in the gut environment, and improved the birds’ colonization resistance to S. sofia.展开更多
From the perspective of black feminism, the feminist consciousness in the novel The Color Purple can be disclosed utterly that Sofia, the supporting role, faces the oppression of the three Giant Mountains, namely, the...From the perspective of black feminism, the feminist consciousness in the novel The Color Purple can be disclosed utterly that Sofia, the supporting role, faces the oppression of the three Giant Mountains, namely, the whites, the black males, and the black females.展开更多
文摘目的探究Sofia远端导管直接抽吸与支架取栓用于急性脑梗死的临床疗效。方法回顾性分析2022年6月至2023年3月乐平市人民医院收治的60例急性脑梗死患者的临床资料,按照治疗方式的不同分为抽吸组(n=35)和支架组(n=25)。抽吸组采用Sofia远端导管直接抽吸治疗,支架组采用支架取栓治疗。比较两组围手术期指标、手术相关并发症发生率、术后血管再通改良脑梗死溶栓血流分级(modified thrombolysis in cerebral infarction scale,mTICI)、美国国立卫生研究所卒中量表(National Institutes of Health stroke scale,NIHSS)评分、血清炎症因子[超敏C反应蛋白(hypersensitive C reactive protein,hs-CRP)、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)]水平以及改良Rankin量表(modified Rankin scale,mRS)评分和日常生活能力量表(activities of daily living scale,ADL)评分。结果抽吸组穿刺-血管成功再通时间短于支架组,取栓次数多于支架组,差异有统计学意义(P<0.05);两组住院时间比较差异无统计学意义。两组手术相关并发症发生率比较差异无统计学意义。抽吸组血管再通分级优于支架组,差异有统计学意义(P<0.05)。术后24 h、7 d,抽吸组NIHSS评分及hs-CRP、TNF-α水平均低于支架组,差异有统计学意义(P<0.05)。术后24 h,两组mRS、ADL评分比较差异无统计学意义;术后7、90 d,抽吸组mRS评分均低于支架组,ADL评分均高于支架组,差异有统计学意义(P<0.05)。结论与支架取栓相比,采用Sofia远端导管抽吸治疗急性脑梗死患者,血管再通时间更短,闭塞血管再通成功率更高,能有效改善患者神经功能、日常生活能力及炎症反应,利于预后,且安全性相当,值得临床推广应用。
文摘目的评估SOFIA远端通路导管直接抽吸治疗早期急性缺血性脑卒中(acute ischemic stroke,AIS)的安全性及有效性。方法选取2018年1月至2019年10月间进行血管内治疗的早期AIS患者65例,其中20例首选SOFIA远端通路导管抽吸取栓治疗(抽吸组),45例首选支架取栓治疗(支架组)。采用改良脑梗死溶栓治疗分级(modified treatment in cerebral ischemia,mTICI)、美国国立卫生研究院卒中量表(National Institute of Health stroke scale,NIHSS)、改良Rankin量表评分(modified rankin scale,mRS)分别评估成功再通及临床预后。对比抽吸组与支架组的手术相关指标(手术时间、血管成功再通)、并发症及临床预后。结果抽吸组较支架组穿刺至血管成功再通时间短,差异具有统计学意义[27(14,36)min vs.34(29,50)min,P<0.05],而血管成功再通率(mTICI 2b/3级)差异无统计学意义(18/20 vs.38/45,P>0.05)。抽吸组与支架组发生血栓逃逸(1/20 vs.3/45)、颅内出血(3/20 vs.7/45)和其他不良事件(1/20 vs.5/45),差异无统计学意义(P>0.05)。抽吸组与支架组术后24 h和7 d NIHSS评分[10(5,13)vs.12(7,17),5(3,11)vs.10(3,15)],90 d mRS评分≤2分及死亡率,差异均无统计学意义(P>0.05)。结论与首选支架取栓相比,SOFIA远端通路导管直接抽吸治疗早期AIS患者具有相似安全性及疗效,且具有操作简单用时短的特点。
文摘The Chinese Proficiency Test(HSK)is a standardized test on Chinese language skills which has been widely introduced both in and outside China and has been playing an important role in the spread of Chinese learning all over the world.In 2003 Bulgaria hosted a beginner level HSK exam,which made it the first location to hold a Chinese language proficiency test on the Balkan Peninsula and ever since it has been very successful.The current paper provides a research on the current state of the Chinese Proficiency Test(HSK)аt the Confucius Institute in Sofia,Bulgaria,analyzes the factors related to the promotion of the Chinese Proficiency Test(HSK)and on this basis presents a few feasible recommendations to the benefit of the Chinese Proficiency Test(HSK).
文摘Objective: to investigate the therapeutic effect of Sofia catheter thrombectomy in elderly patients with acute ischemic stroke. Methods 22: elderly patients with acute ischemic stroke who underwent Sofia catheter thrombectomy (or) combined with stenting in Beijing Chaoyang integrated traditional Chinese and Western medicine emergency rescue center from January 2021 to December 2021 were analyzed retrospectively, including 8 cases of simple Sofia aspiration and 14 cases of combined stent thrombectomy. The general data, clinical characteristics and imaging manifestations of patients were analyzed. The improved thrombolytic test standard for cerebral infarction (mtici) was used to evaluate the patency of blood vessels. Grade 0-2a was occluded, and grade 2b-3 was successful recanalization;The National Institutes of health neurological deficit score (NIHSS) and the modified Rankin score (MRS) were evaluated before and after operation. Results: among the 22 elderly patients, there were 7 male patients and 15 female patients;The patients were 81-94 years old, with an average age of 84.45 ± 3.32 years. The Glasgow Coma Scale (GCS) score before admission was 4-10, with an average score of 7.95 ± 2.40.The blocked sites were basilar artery in 2 cases, bilateral posterior cerebral artery in 1 case, bilateral internal carotid artery in 1 case, right middle cerebral artery in 1 case, right internal carotid artery in 7 cases, left middle cerebral artery in 7 cases and left internal carotid artery in 3 cases. Preoperative intravenous thrombolysis was performed in 9 patients.22 elderly patients were rated by mtici after treatment. It can be seen that there were 2 patients with grade 2A (9.09%), 6 patients with grade 2B (27.27%) and 14 patients with grade 3 (63.64%).There was no significant difference in NIHSS score between patients after treatment and before treatment (18.18 ± 6.82 vs. 18.77 ± 5.98, P > 0.05).Among the 22 patients, 13 (59.09%) died due to complications or family members giving up rescue. Conclusion: Sofia catheter thrombectomy can effectively improve vascular occlusion, but it should be used with clinical caution in elderly patients.
文摘The film The Color Purple mainly talks about the bitter situation of oppression and discrimination of American black wom-en through the life of protagonist Celie, and Celie’s spiritual journey of becoming awaken gradually and independent, and at last gain her own new life. Another black woman Sofia in the film has confidence, independence and fighting spirit. This paper will analyzes Sofia’s three personalities from the perspective of Freudian psychoanalysis, especially his theory of personality which divides the psyche into the id, the self, and the superego so as to better understand black wom-en’inner world in the oppression and discrimination society.
文摘The effects of Lactobacillus johnsonii(L. johnsonii) on gut microflora, bird performance and intestinal development were assessed using 288 one-day-old Cobb broilers challenged with Salmonella sofia(S.sofia). The experiment was a 3×2 factorial design which consisted of three treatments, a negative control(NC) with no additives, a positive control(PC) containing antimicrobials(zinc-bacitracin, 50 mg/kg) and a probiotic group(Pro), and with the two factors being unchallenged or challenged with S. sofia.A probiotic preparation of L. johnsonii(10~9 cfu/chick) was administered to chicks individually by oral gavage on days 1, 3, 7 and 12. Chicks were individually challenged with S. sofia(10~7 cfu/chick) by oral gavage on d 2, 8 and 13. Results showed that the challenge itself markedly reduced(P < 0.05) bird performance and feed intake. And, transient clinical symptoms of the infection with S. sofia were observed from the second time they were challenged with S. sofia in the negative challenge groups. The novel probiotic candidate L. johnsonii reduced the number of S. sofia and Clostridium perfringens in the gut environment, and improved the birds’ colonization resistance to S. sofia.
文摘From the perspective of black feminism, the feminist consciousness in the novel The Color Purple can be disclosed utterly that Sofia, the supporting role, faces the oppression of the three Giant Mountains, namely, the whites, the black males, and the black females.
