The differences among the extended Canetti ＆ Krawezyk 2007 model （ECK2007） and other four models, i.e., the Bellare ＆ Rogaway （1993, 1995）models （BR93,BR95）, the Bellare, Pointcheval ＆ Rogaway （2000） model ...The differences among the extended Canetti ＆ Krawezyk 2007 model （ECK2007） and other four models, i.e., the Bellare ＆ Rogaway （1993, 1995）models （BR93,BR95）, the Bellare, Pointcheval ＆ Rogaway （2000） model （BPR2000） and the Canetti ＆ Krawczyk （2001） model （CK2001） are given. The relative strength of security among these models is analyzed. To support the implication or non-implication relation among these models, the formal proof or the counter-example is provided.展开更多
An efficient authenticated key agreement protocol is proposed, which makesuse of bilinear pairings and self-certificd public keys. Its security is based on the securityassumptions of the bilinear Diff ie-Hellman probl...An efficient authenticated key agreement protocol is proposed, which makesuse of bilinear pairings and self-certificd public keys. Its security is based on the securityassumptions of the bilinear Diff ie-Hellman problem and the computational Diffie-Hellman problem.Users can choose their private keys independently. The public keys and identities of users can beverified implicitly when the session key being generating in a logically single step. A trusted KeyGeneration Center is no longer requiredas in the ID-based authenticated key agreement protocolsCompared with existing authenticated key agreement protocols from pairings, the. new proposedprotocol is more efficient and secure.展开更多
The emergence of quantum computer will threaten the security of existing public-key cryptosystems, including the Diffie Hellman key exchange protocol, encryption scheme and etc, and it makes the study of resistant qua...The emergence of quantum computer will threaten the security of existing public-key cryptosystems, including the Diffie Hellman key exchange protocol, encryption scheme and etc, and it makes the study of resistant quantum cryptography very urgent. This motivate us to design a new key exchange protocol and eneryption scheme in this paper. Firstly, some acknowledged mathematical problems was introduced, such as ergodic matrix problem and tensor decomposition problem, the two problems have been proved to NPC hard. From the computational complexity prospective, NPC problems have been considered that there is no polynomial-time quantum algorithm to solve them. From the algebraic structures prospective, non-commutative cryptography has been considered to resist quantum. The matrix and tensor operator we adopted also satisfied with this non-commutative algebraic structures, so they can be used as candidate problems for resisting quantum from perspective of computational complexity theory and algebraic structures. Secondly, a new problem was constructed based on the introduced problems in this paper, then a key exchange protocol and a public key encryption scheme were proposed based on it. Finally the security analysis, efficiency, recommended parameters, performance evaluation and etc. were also been given. The two schemes has the following characteristics, provable security,security bits can be scalable, to achieve high efficiency, quantum resistance, and etc.展开更多
The certificateless authenticated key agreement protocol proposed by Mandt et al does not haVE the property of key-compromise impersonation （K-CI） resilience. An improved protocol with a simple modification of their...The certificateless authenticated key agreement protocol proposed by Mandt et al does not haVE the property of key-compromise impersonation （K-CI） resilience. An improved protocol with a simple modification of their protocol is proposed in this paper. In particular, our improved protocol is proved to be immune to the K-CI attack and at the same time possess other security properties.展开更多
Within the framework of universal composability,an appropriate ideal functionality that captures the basic security requirements of three party password-based key exchange was defined. An efficient real-word three par...Within the framework of universal composability,an appropriate ideal functionality that captures the basic security requirements of three party password-based key exchange was defined. An efficient real-word three party password-based key exchange protocol was also proposed.This protocol securely realizes the ideal functionality with respect to static party corruption.Thus it provides security guarantees under arbitrary composition with other protocols.展开更多
Secure key distribution among classical parties is impossible both between two parties and in a network. In this paper, we present a quantum key distribution （QKD） protocol to distribute secure key bits among one qu...Secure key distribution among classical parties is impossible both between two parties and in a network. In this paper, we present a quantum key distribution （QKD） protocol to distribute secure key bits among one quantum party and numerous classical parties who have no quantum capacity. We prove that our protocol is completely robust, i.e., any eavesdropping attack should be detected with nonzero probability. Our calculations show that our protocol may be secure against Eve＇s symmetrically individual attack.展开更多
This paper proposed two modifications on IKE protocol with pre-shared key authentication. The first modification can improve its immunity against DDoS attack by authenticating the initiator before the responder genera...This paper proposed two modifications on IKE protocol with pre-shared key authentication. The first modification can improve its immunity against DDoS attack by authenticating the initiator before the responder generates the computation-intensive Diffie-Hellman public value. The second modification can improve its efficiency when the attack on messages occurs because it can detect the attack quickly by replacing the centralized authentication in origical IKE protocol with immediate authentication. In addition, the two modifications can be integrated into one protocol compactly.展开更多
It is established that a single quantum cryptography protocol usually cooperates with other cryptographicsystems,such as an authentication system,in the real world.However,few protocols have been proposed on how tocom...It is established that a single quantum cryptography protocol usually cooperates with other cryptographicsystems,such as an authentication system,in the real world.However,few protocols have been proposed on how tocombine two or more quantum protocols.To fill this gap,we propose a composed quantum protocol,containing bothquantum identity authentication and quantum key distribution,using squeezed states.Hence,not only the identity canbe verified,but also a new private key can be generated by our new protocol.We also analyze the security under anoptimal attack,and the efficiency,which is defined by the threshold of the tolerant error rate,using Gaussian errorfunction.展开更多
Combined public key （CPK） cryptography does not need certificates to guarantee the authenticity of public keys and avoids the inherent key escrow problem of identity-based cryptography. Based on the efficient CPK sc...Combined public key （CPK） cryptography does not need certificates to guarantee the authenticity of public keys and avoids the inherent key escrow problem of identity-based cryptography. Based on the efficient CPK scheme, we present an efficient three-round two-party authenticated key exchange protocol with strong security, which is provably secure in the standard model under the decisional Diffie-Hellman （DDH） assumption. The protocol can keep the session key secret from the adversary except that one party＇s ephemeral private key and static private key are all revealed to the adversary. Compared to the existing protocols, this protocol not only assures strong security but also is more efficient.展开更多
A new efficient two-party semi-quantum key agreement protocol is proposed with high-dimensional single-particle states.Different from the previous semi-quantum key agreement protocols based on the two-level quantum sy...A new efficient two-party semi-quantum key agreement protocol is proposed with high-dimensional single-particle states.Different from the previous semi-quantum key agreement protocols based on the two-level quantum system,the propounded protocol makes use of the advantage of the high-dimensional quantum system,which possesses higher efficiency and better robustness against eavesdropping.Besides,the protocol allows the classical participant to encode the secret key with qudit shifting operations without involving any quantum measurement abilities.The designed semi-quantum key agreement protocol could resist both participant attacks and outsider attacks.Meanwhile,the conjoint analysis of security and efficiency provides an appropriate choice for reference on the dimension of single-particle states and the number of decoy states.展开更多
This article discusses the evolving real-world practice using nitazoxanide,nonsteroidal anti-inflammatory drugs(NSAIDs)and/or azithromycin(Kelleni’s protocol)to manage the evolving manifestations of severe acute resp...This article discusses the evolving real-world practice using nitazoxanide,nonsteroidal anti-inflammatory drugs(NSAIDs)and/or azithromycin(Kelleni’s protocol)to manage the evolving manifestations of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)Omicron EG.5.1,its descendant HV.1 as well as BA.2.86 and its descendant JN.1 subvariants in Egypt in 2024.These subvariants are well-known for their highly evolved immune-evasive properties and the manifestations include some peculiar manifestations as persistent cough besides high fever in young children as well as high fever,persistent severe cough,change of voice,loss of taste and smell,epigastric pain,nausea,vomiting,diarrhea,generalized malaise and marked bone aches in adults including the high-risk groups.It’s suggested that the ongoing SARS-CoV-2 evolution is continuing to mostly affect the high-risk groups of patients,to some of whom we’ve also successfully prescribed nitazoxanide and/or NSAIDs for post-exposure prophylaxis of all household contacts.We also continue to recommend starting the immune-modulatory antiviral Kelleni’s protocol as soon as possible in the course of infection and adjusting it in a personalized manner to be more aggressive from the beginning for the high risk patients,at least until the currently encountered surge of infections subsides.展开更多
To guarantee the security of communication in the public channel, many key agreement protocols have been proposed. Recently, Gong et al. proposed a key agreement protocol based on chaotic maps with password sharing. I...To guarantee the security of communication in the public channel, many key agreement protocols have been proposed. Recently, Gong et al. proposed a key agreement protocol based on chaotic maps with password sharing. In this paper, Gong et al.＇s protocol is analyzed, and we find that this protocol exhibits key management issues and potential security problems. Furthermore, the paper presents a new key agreement protocol based on enhanced Chebyshev polynomials to overcome these problems. Through our analysis, our key agreement protocol not only provides mutual authentication and the ability to resist a variety of conarnon attacks, but also solve the problems of key management and security issues existing in Gong et al.＇ s protocol.展开更多
This paper addresses an interesting security problem in wireless ad hoc networks: the dynamic group key agreement key establishment. For secure group communication in an ad hoc network, a group key shared by all group...This paper addresses an interesting security problem in wireless ad hoc networks: the dynamic group key agreement key establishment. For secure group communication in an ad hoc network, a group key shared by all group members is required. This group key should be updated when there are membership changes (when the new member joins or current member leaves) in the group. In this paper, we propose a novel, secure, scalable and efficient region-based group key agreement protocol for ad hoc networks. This is implemented by a two-level structure and a new scheme of group key update. The idea is to divide the group into subgroups, each maintaining its subgroup keys using group elliptic curve diffie-hellman (GECDH) Protocol and links with other subgroups in a tree structure using tree-based group elliptic curve diffie-hellman (TGECDH) protocol. By introducing region-based approach, messages and key updates will be limited within subgroup and outer group;hence computation load is distributed to many hosts. Both theoretical analysis and experimental results show that this Region-based key agreement protocol performs well for the key establishment problem in ad hoc network in terms of memory cost, computation cost and communication cost.展开更多
The current recommendation to avoid non-steroidal anti-inflammatory drugs(NSAIDs)in the management of dengue virus disease(DVD)is scientifically considered of very low to low certainty,despite being widely adopted wor...The current recommendation to avoid non-steroidal anti-inflammatory drugs(NSAIDs)in the management of dengue virus disease(DVD)is scientifically considered of very low to low certainty,despite being widely adopted worldwide.The same recommendation,initially made during the coronavirus disease 2019(COVID-19)pandemic,was subsequently proven incorrect.In this clinical report,we present evidence,for the first time globally,from a real-life practice that NSAIDs may actually be lifesaving in the early management of DVD as they have proved to be in COVID-19.Moreover,we propose that the personalized immunemodulatory Kelleni’s protocol,which includes nitazoxanide as a key component,can be safely and effectively used to manage various separate or concomitant viral infections and co-infections,including DVD.Importantly,this article contributes to the current medical knowledge in the global pursuit of a safe and effective broad-spectrum antiviral protocol that can be used to early manage multiple highly infectious viruses.However,it’s crucial that sufficiently powered controlled randomized clinical trials be conducted to thoroughly assess and evaluate the safety of NSAIDs in the early management of DVD as well as the efficacy of nitazoxanide with or without NSAIDs in its management.展开更多
BACKGROUND Lower respiratory tract viral infections are a major cause of mortality in children under five years old,leading to hundreds of thousands of fatalities annually.The highest risk is observed in infants under...BACKGROUND Lower respiratory tract viral infections are a major cause of mortality in children under five years old,leading to hundreds of thousands of fatalities annually.The highest risk is observed in infants under one year old,underscoring the critical need for safe and effective antiviral protocols.CASE SUMMARY A 9-month-old infant suffered from severe bronchiolitis as manifested by high fever(39°C),decreased appetite,tachypnea,wheezing,and oxygen desaturation(SpO284%on room air)and was effectively managed at home using Kelleni’s protocol,which includes age-adjusted dose of nitazoxanide(60 mg twice daily),ibuprofen and azithromycin,complemented by selective antihistaminic,antitussive and mucolytic immunomodulatory treatment.The fever resolved,wheezing became more prominent but without respiratory distress,and oxygen saturation gradually increased to 92%by day 10.Nitazoxanide exerts broad antiviral and immunomodulatory effects by enhancing host interferon responses and inhibiting viral replication,potentially attenuating airway inflammation and accelerating resolution of bronchiolitis.The nitazoxanide dose(60 mg twice daily for five days)was carefully adjusted based on the developmental expression and activity of the uridine diphosphate-glucuronosyltransferase 1A1 enzyme,responsible for its metabolism,ensuring safe age-appropriate administration.The infant’s clinical status steadily improved,and by day 14 the infant achieved full recovery with normalization of oxygen saturation(96%on room air).No adverse events occurred,and follow-up at day 28 confirmed sustained recovery.CONCLUSION To the best of my knowledge,this report presents,for the first time globally,a potential of nitazoxanide within Kelleni’s protocol to early manage infants younger than one year suffering from severe lower respiratory tract viral infection at home.Selective antitussive treatment,using agents such as low dose benproperine,was employed to mitigate troublesome cough and improve patient comfort without compromising respiratory function.Additionally,alpha amylase was used to facilitate pulmonary secretion clearance.The protocol aims to reduce morbidity and mortality from viral lower respiratory tract infections in this vulnerable population.展开更多
Quantum key distribution(QKD) generates information-theoretical secret keys between two parties based on the physical laws of quantum mechanics. Following the advancement in quantum communication networks, it becomes ...Quantum key distribution(QKD) generates information-theoretical secret keys between two parties based on the physical laws of quantum mechanics. Following the advancement in quantum communication networks, it becomes feasible and economical to combine QKD with classical optical communication through the same fiber using dense wavelength division multiplexing(DWDM) technology. This study proposes a detailed scheme of TF-QKD protocol with DWDM technology and analyzes its performance, considering the influence of quantum channel number and adjacent quantum crosstalk on the secret key rates. The simulation results show that the scheme further increases the secret key rate of TF-QKD and its variants. Therefore, this scheme provides a method for improving the secret key rate for practical quantum networks.展开更多
Canetti and Herzog have already proposed universally composable symbolic analysis(UCSA) to analyze mutual authentication and key exchange protocols. However,they do not analyze group key exchange protocol. Therefore,t...Canetti and Herzog have already proposed universally composable symbolic analysis(UCSA) to analyze mutual authentication and key exchange protocols. However,they do not analyze group key exchange protocol. Therefore,this paper explores an approach to analyze group key exchange protocols,which realize automation and guarantee the soundness of cryptography. Considered that there exist many kinds of group key exchange protocols and the participants’ number of each protocol is arbitrary. So this paper takes the case of Burmester-Desmedt(BD) protocol with three participants against passive adversary(3-BD-Passive) . In a nutshell,our works lay the root for analyzing group key exchange protocols automatically without sacrificing soundness of cryptography.展开更多
Certificateless one-round key exchange(CL-ORKE)protocols enable each participant to share a common key with only one round of communication which greatly saves communication cost.CLORKE protocols can be applied to sce...Certificateless one-round key exchange(CL-ORKE)protocols enable each participant to share a common key with only one round of communication which greatly saves communication cost.CLORKE protocols can be applied to scenarios with limited communication,such as space communication.Although CL-ORKE protocols have been researched for years,lots of them only consider what secrets can be compromised but ignore the time when the secrets have been corrupted.In CL-ORKE protocols,the reveal of the long-term key attacks can be divided into two different attacks according to the time of the long-term key revealed:the attack to weak Forward Security(wFS)and the attack to strong Forward Security(sFS).Many CLKE protocols did not take into account the sFS property or considered sFS as wFS.In this paper,we first propose a new security model for CL-ORKE protocols which considers the sFS property as well as the Ephemeral Key Reveal attack.Then,we give a CL-ORKE protocol which is called CLORKE-SFS.CLORKE-SFS is provably secure under the proposed model provided the Elliptic Curve Computational Diffie-Hellman(ECCDH)and the Bilinear Computational Diffie-Hellman problem(BCDH)assumption hold.The security model and the protocol may give inspiration for constructing oneround key exchange protocols with perfect forward security in certificateless scenarios.展开更多
Forward secrecy is an important security property in key agreement protocol. Based on Ham＇s protocol, in this paper a new authenticated Diffie-Hellman key agreement protocol with half forward secrecy is proposed. Thi...Forward secrecy is an important security property in key agreement protocol. Based on Ham＇s protocol, in this paper a new authenticated Diffie-Hellman key agreement protocol with half forward secrecy is proposed. This protocol is also based on a single cryptographic assumption, and is user authentication and shared key authentication. More importantly, our protocol provides forward secrecy with respect to one of the parties. For this reason, besides the advantages of Ham＇s protocol, in practice, our protocol can reduce the damages resulted from the disclosure of the user＇s secret key and it is very beneficial to today＇s communication with portable devices.展开更多
Three-party password-based key agreement protocols allow two users to authenticate each other via a public channel and establish a session key with the aid of a trusted server. Recently, Farash et al. [Farash M S, Att...Three-party password-based key agreement protocols allow two users to authenticate each other via a public channel and establish a session key with the aid of a trusted server. Recently, Farash et al. [Farash M S, Attari M A 2014 ＂An efficient and provably secure three-party password-based authenticated key exchange protocol based on Chebyshev chaotic maps＂, Nonlinear Dynamics 77（7）： 399-411] proposed a three-party key agreement protocol by using the extended chaotic maps. They claimed that their protocol could achieve strong security. In the present paper, we analyze Farash et al.＇s protocol and point out that this protocol is vulnerable to off-line password guessing attack and suffers communication burden. To handle the issue, we propose an efficient three-party password-based key agreement protocol using extended chaotic maps, which uses neither symmetric cryptosystems nor the server＇s public key. Compared with the relevant schemes, our protocol provides better performance in terms of computation and communication. Therefore, it is suitable for practical applications.展开更多
文摘The differences among the extended Canetti ＆ Krawezyk 2007 model （ECK2007） and other four models, i.e., the Bellare ＆ Rogaway （1993, 1995）models （BR93,BR95）, the Bellare, Pointcheval ＆ Rogaway （2000） model （BPR2000） and the Canetti ＆ Krawczyk （2001） model （CK2001） are given. The relative strength of security among these models is analyzed. To support the implication or non-implication relation among these models, the formal proof or the counter-example is provided.
文摘An efficient authenticated key agreement protocol is proposed, which makesuse of bilinear pairings and self-certificd public keys. Its security is based on the securityassumptions of the bilinear Diff ie-Hellman problem and the computational Diffie-Hellman problem.Users can choose their private keys independently. The public keys and identities of users can beverified implicitly when the session key being generating in a logically single step. A trusted KeyGeneration Center is no longer requiredas in the ID-based authenticated key agreement protocolsCompared with existing authenticated key agreement protocols from pairings, the. new proposedprotocol is more efficient and secure.
基金the National Natural Science Foundation of China，the State Key Program of National Natural Science of China，the Major Research Plan of the National Natural Science Foundation of China，Major State Basic Research Development Program of China (973 Program)，the Hubei Natural Science Foundation of China
文摘The emergence of quantum computer will threaten the security of existing public-key cryptosystems, including the Diffie Hellman key exchange protocol, encryption scheme and etc, and it makes the study of resistant quantum cryptography very urgent. This motivate us to design a new key exchange protocol and eneryption scheme in this paper. Firstly, some acknowledged mathematical problems was introduced, such as ergodic matrix problem and tensor decomposition problem, the two problems have been proved to NPC hard. From the computational complexity prospective, NPC problems have been considered that there is no polynomial-time quantum algorithm to solve them. From the algebraic structures prospective, non-commutative cryptography has been considered to resist quantum. The matrix and tensor operator we adopted also satisfied with this non-commutative algebraic structures, so they can be used as candidate problems for resisting quantum from perspective of computational complexity theory and algebraic structures. Secondly, a new problem was constructed based on the introduced problems in this paper, then a key exchange protocol and a public key encryption scheme were proposed based on it. Finally the security analysis, efficiency, recommended parameters, performance evaluation and etc. were also been given. The two schemes has the following characteristics, provable security,security bits can be scalable, to achieve high efficiency, quantum resistance, and etc.
基金the National Natural Science Foundation of China (60773086)
文摘The certificateless authenticated key agreement protocol proposed by Mandt et al does not haVE the property of key-compromise impersonation （K-CI） resilience. An improved protocol with a simple modification of their protocol is proposed in this paper. In particular, our improved protocol is proved to be immune to the K-CI attack and at the same time possess other security properties.
基金Project(60573036)supported by the National Natural Science Foundation of china
文摘Within the framework of universal composability,an appropriate ideal functionality that captures the basic security requirements of three party password-based key exchange was defined. An efficient real-word three party password-based key exchange protocol was also proposed.This protocol securely realizes the ideal functionality with respect to static party corruption.Thus it provides security guarantees under arbitrary composition with other protocols.
基金Project supported by the National Natural Science Foundation of China (Grant No 10774039)
文摘Secure key distribution among classical parties is impossible both between two parties and in a network. In this paper, we present a quantum key distribution （QKD） protocol to distribute secure key bits among one quantum party and numerous classical parties who have no quantum capacity. We prove that our protocol is completely robust, i.e., any eavesdropping attack should be detected with nonzero probability. Our calculations show that our protocol may be secure against Eve＇s symmetrically individual attack.
文摘This paper proposed two modifications on IKE protocol with pre-shared key authentication. The first modification can improve its immunity against DDoS attack by authenticating the initiator before the responder generates the computation-intensive Diffie-Hellman public value. The second modification can improve its efficiency when the attack on messages occurs because it can detect the attack quickly by replacing the centralized authentication in origical IKE protocol with immediate authentication. In addition, the two modifications can be integrated into one protocol compactly.
基金Supported by the National Natural Science Foundation of China under Grant No. 60872052
文摘It is established that a single quantum cryptography protocol usually cooperates with other cryptographicsystems,such as an authentication system,in the real world.However,few protocols have been proposed on how tocombine two or more quantum protocols.To fill this gap,we propose a composed quantum protocol,containing bothquantum identity authentication and quantum key distribution,using squeezed states.Hence,not only the identity canbe verified,but also a new private key can be generated by our new protocol.We also analyze the security under anoptimal attack,and the efficiency,which is defined by the threshold of the tolerant error rate,using Gaussian errorfunction.
基金Supported by the Key Laboratory Foundation of Communication Technology of China (9140C1103040902)
文摘Combined public key （CPK） cryptography does not need certificates to guarantee the authenticity of public keys and avoids the inherent key escrow problem of identity-based cryptography. Based on the efficient CPK scheme, we present an efficient three-round two-party authenticated key exchange protocol with strong security, which is provably secure in the standard model under the decisional Diffie-Hellman （DDH） assumption. The protocol can keep the session key secret from the adversary except that one party＇s ephemeral private key and static private key are all revealed to the adversary. Compared to the existing protocols, this protocol not only assures strong security but also is more efficient.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.61871205 and 61561033)the Major Academic Discipline and Technical Leader of Jiangxi Province,China(Grant No.20162BCB22011).
文摘A new efficient two-party semi-quantum key agreement protocol is proposed with high-dimensional single-particle states.Different from the previous semi-quantum key agreement protocols based on the two-level quantum system,the propounded protocol makes use of the advantage of the high-dimensional quantum system,which possesses higher efficiency and better robustness against eavesdropping.Besides,the protocol allows the classical participant to encode the secret key with qudit shifting operations without involving any quantum measurement abilities.The designed semi-quantum key agreement protocol could resist both participant attacks and outsider attacks.Meanwhile,the conjoint analysis of security and efficiency provides an appropriate choice for reference on the dimension of single-particle states and the number of decoy states.
文摘This article discusses the evolving real-world practice using nitazoxanide,nonsteroidal anti-inflammatory drugs(NSAIDs)and/or azithromycin(Kelleni’s protocol)to manage the evolving manifestations of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)Omicron EG.5.1,its descendant HV.1 as well as BA.2.86 and its descendant JN.1 subvariants in Egypt in 2024.These subvariants are well-known for their highly evolved immune-evasive properties and the manifestations include some peculiar manifestations as persistent cough besides high fever in young children as well as high fever,persistent severe cough,change of voice,loss of taste and smell,epigastric pain,nausea,vomiting,diarrhea,generalized malaise and marked bone aches in adults including the high-risk groups.It’s suggested that the ongoing SARS-CoV-2 evolution is continuing to mostly affect the high-risk groups of patients,to some of whom we’ve also successfully prescribed nitazoxanide and/or NSAIDs for post-exposure prophylaxis of all household contacts.We also continue to recommend starting the immune-modulatory antiviral Kelleni’s protocol as soon as possible in the course of infection and adjusting it in a personalized manner to be more aggressive from the beginning for the high risk patients,at least until the currently encountered surge of infections subsides.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.61370145,61173183,and 60973152)the Doctoral Program Foundation of Institution of Higher Education of China(Grant No.20070141014)+2 种基金the Program for Excellent Talents in Universities of Liaoning Province,China(Grant No.LR2012003)the Natural Science Foundation of Liaoning Province,China(Grant No.20082165)the Fundamental Research Funds for the Central Universities of China(Grant No.DUT12JB06)
文摘To guarantee the security of communication in the public channel, many key agreement protocols have been proposed. Recently, Gong et al. proposed a key agreement protocol based on chaotic maps with password sharing. In this paper, Gong et al.＇s protocol is analyzed, and we find that this protocol exhibits key management issues and potential security problems. Furthermore, the paper presents a new key agreement protocol based on enhanced Chebyshev polynomials to overcome these problems. Through our analysis, our key agreement protocol not only provides mutual authentication and the ability to resist a variety of conarnon attacks, but also solve the problems of key management and security issues existing in Gong et al.＇ s protocol.
文摘This paper addresses an interesting security problem in wireless ad hoc networks: the dynamic group key agreement key establishment. For secure group communication in an ad hoc network, a group key shared by all group members is required. This group key should be updated when there are membership changes (when the new member joins or current member leaves) in the group. In this paper, we propose a novel, secure, scalable and efficient region-based group key agreement protocol for ad hoc networks. This is implemented by a two-level structure and a new scheme of group key update. The idea is to divide the group into subgroups, each maintaining its subgroup keys using group elliptic curve diffie-hellman (GECDH) Protocol and links with other subgroups in a tree structure using tree-based group elliptic curve diffie-hellman (TGECDH) protocol. By introducing region-based approach, messages and key updates will be limited within subgroup and outer group;hence computation load is distributed to many hosts. Both theoretical analysis and experimental results show that this Region-based key agreement protocol performs well for the key establishment problem in ad hoc network in terms of memory cost, computation cost and communication cost.
文摘The current recommendation to avoid non-steroidal anti-inflammatory drugs(NSAIDs)in the management of dengue virus disease(DVD)is scientifically considered of very low to low certainty,despite being widely adopted worldwide.The same recommendation,initially made during the coronavirus disease 2019(COVID-19)pandemic,was subsequently proven incorrect.In this clinical report,we present evidence,for the first time globally,from a real-life practice that NSAIDs may actually be lifesaving in the early management of DVD as they have proved to be in COVID-19.Moreover,we propose that the personalized immunemodulatory Kelleni’s protocol,which includes nitazoxanide as a key component,can be safely and effectively used to manage various separate or concomitant viral infections and co-infections,including DVD.Importantly,this article contributes to the current medical knowledge in the global pursuit of a safe and effective broad-spectrum antiviral protocol that can be used to early manage multiple highly infectious viruses.However,it’s crucial that sufficiently powered controlled randomized clinical trials be conducted to thoroughly assess and evaluate the safety of NSAIDs in the early management of DVD as well as the efficacy of nitazoxanide with or without NSAIDs in its management.
文摘BACKGROUND Lower respiratory tract viral infections are a major cause of mortality in children under five years old,leading to hundreds of thousands of fatalities annually.The highest risk is observed in infants under one year old,underscoring the critical need for safe and effective antiviral protocols.CASE SUMMARY A 9-month-old infant suffered from severe bronchiolitis as manifested by high fever(39°C),decreased appetite,tachypnea,wheezing,and oxygen desaturation(SpO284%on room air)and was effectively managed at home using Kelleni’s protocol,which includes age-adjusted dose of nitazoxanide(60 mg twice daily),ibuprofen and azithromycin,complemented by selective antihistaminic,antitussive and mucolytic immunomodulatory treatment.The fever resolved,wheezing became more prominent but without respiratory distress,and oxygen saturation gradually increased to 92%by day 10.Nitazoxanide exerts broad antiviral and immunomodulatory effects by enhancing host interferon responses and inhibiting viral replication,potentially attenuating airway inflammation and accelerating resolution of bronchiolitis.The nitazoxanide dose(60 mg twice daily for five days)was carefully adjusted based on the developmental expression and activity of the uridine diphosphate-glucuronosyltransferase 1A1 enzyme,responsible for its metabolism,ensuring safe age-appropriate administration.The infant’s clinical status steadily improved,and by day 14 the infant achieved full recovery with normalization of oxygen saturation(96%on room air).No adverse events occurred,and follow-up at day 28 confirmed sustained recovery.CONCLUSION To the best of my knowledge,this report presents,for the first time globally,a potential of nitazoxanide within Kelleni’s protocol to early manage infants younger than one year suffering from severe lower respiratory tract viral infection at home.Selective antitussive treatment,using agents such as low dose benproperine,was employed to mitigate troublesome cough and improve patient comfort without compromising respiratory function.Additionally,alpha amylase was used to facilitate pulmonary secretion clearance.The protocol aims to reduce morbidity and mortality from viral lower respiratory tract infections in this vulnerable population.
基金supported by the State Key Laboratory of Information Photonics and Optical Communications, Beijing University of Posts and Telecommunications (Grant No. IPOC2021ZT10)the National Natural Science Foundation of China (Grant No. 11904333)+1 种基金the Fundamental Research Funds for the Central Universities (Grant No. 2019XD-A02)BUPT Innovation and Entrepreneurship Support Program (Grant No. 2022YC-T051)。
文摘Quantum key distribution(QKD) generates information-theoretical secret keys between two parties based on the physical laws of quantum mechanics. Following the advancement in quantum communication networks, it becomes feasible and economical to combine QKD with classical optical communication through the same fiber using dense wavelength division multiplexing(DWDM) technology. This study proposes a detailed scheme of TF-QKD protocol with DWDM technology and analyzes its performance, considering the influence of quantum channel number and adjacent quantum crosstalk on the secret key rates. The simulation results show that the scheme further increases the secret key rate of TF-QKD and its variants. Therefore, this scheme provides a method for improving the secret key rate for practical quantum networks.
基金supported by National Natural Science Foundation of China No.61003262,National Natural Science Foundation of China No.60873237Doctoral Fund of Ministry of Education of China No.20070007071
文摘Canetti and Herzog have already proposed universally composable symbolic analysis(UCSA) to analyze mutual authentication and key exchange protocols. However,they do not analyze group key exchange protocol. Therefore,this paper explores an approach to analyze group key exchange protocols,which realize automation and guarantee the soundness of cryptography. Considered that there exist many kinds of group key exchange protocols and the participants’ number of each protocol is arbitrary. So this paper takes the case of Burmester-Desmedt(BD) protocol with three participants against passive adversary(3-BD-Passive) . In a nutshell,our works lay the root for analyzing group key exchange protocols automatically without sacrificing soundness of cryptography.
基金This work was supported by the National Natural Science Foundation of China(NSFC)under Grant(61902049,31960119)Joint Special Fund for Basic Research of Local Undergraduate Universities(Parts)in Yunnan Province under Grant(2018FH001-063,2018FH001-106)Dali University Innovation Team Project(ZKLX2020308).
文摘Certificateless one-round key exchange(CL-ORKE)protocols enable each participant to share a common key with only one round of communication which greatly saves communication cost.CLORKE protocols can be applied to scenarios with limited communication,such as space communication.Although CL-ORKE protocols have been researched for years,lots of them only consider what secrets can be compromised but ignore the time when the secrets have been corrupted.In CL-ORKE protocols,the reveal of the long-term key attacks can be divided into two different attacks according to the time of the long-term key revealed:the attack to weak Forward Security(wFS)and the attack to strong Forward Security(sFS).Many CLKE protocols did not take into account the sFS property or considered sFS as wFS.In this paper,we first propose a new security model for CL-ORKE protocols which considers the sFS property as well as the Ephemeral Key Reveal attack.Then,we give a CL-ORKE protocol which is called CLORKE-SFS.CLORKE-SFS is provably secure under the proposed model provided the Elliptic Curve Computational Diffie-Hellman(ECCDH)and the Bilinear Computational Diffie-Hellman problem(BCDH)assumption hold.The security model and the protocol may give inspiration for constructing oneround key exchange protocols with perfect forward security in certificateless scenarios.
基金Supported by the National Natural Science Foundation of China (60873233)the Nature Science Foundation of Shaanxi Province, China (2006F19)the Technology Research Program of Xi’an, China (CXY08016)
文摘Forward secrecy is an important security property in key agreement protocol. Based on Ham＇s protocol, in this paper a new authenticated Diffie-Hellman key agreement protocol with half forward secrecy is proposed. This protocol is also based on a single cryptographic assumption, and is user authentication and shared key authentication. More importantly, our protocol provides forward secrecy with respect to one of the parties. For this reason, besides the advantages of Ham＇s protocol, in practice, our protocol can reduce the damages resulted from the disclosure of the user＇s secret key and it is very beneficial to today＇s communication with portable devices.
基金Project supported by the National Natural Science Foundation of China(Grant No.61462033)
文摘Three-party password-based key agreement protocols allow two users to authenticate each other via a public channel and establish a session key with the aid of a trusted server. Recently, Farash et al. [Farash M S, Attari M A 2014 ＂An efficient and provably secure three-party password-based authenticated key exchange protocol based on Chebyshev chaotic maps＂, Nonlinear Dynamics 77（7）： 399-411] proposed a three-party key agreement protocol by using the extended chaotic maps. They claimed that their protocol could achieve strong security. In the present paper, we analyze Farash et al.＇s protocol and point out that this protocol is vulnerable to off-line password guessing attack and suffers communication burden. To handle the issue, we propose an efficient three-party password-based key agreement protocol using extended chaotic maps, which uses neither symmetric cryptosystems nor the server＇s public key. Compared with the relevant schemes, our protocol provides better performance in terms of computation and communication. Therefore, it is suitable for practical applications.
