With the iteration and upgrading of medical technology and the continuous growth of public health demands,the quality of nursing services has become a core indicator for measuring the effectiveness of the medical syst...With the iteration and upgrading of medical technology and the continuous growth of public health demands,the quality of nursing services has become a core indicator for measuring the effectiveness of the medical system.The clinical practice ability of nursing staff is directly related to the safety of patient diagnosis and treatment and the rehabilitation process.However,the current clinical nursing talent training model is facing bottlenecks such as limited practical scenarios and fragmented case cognition.This study focuses on the teaching application of augmented reality(AR)technology in hospital Settings and systematically reviews the research progress on the improvement of clinical practice ability of trainee nurses based on the AR immersive teaching model.By constructing a clinical teaching scenario that integrates virtual and real,AR technology can dynamically simulate complex case handling processes and enhance nursing students’three-dimensional cognition of condition assessment,operation norms,and emergency plans.Hospitals,as the core base for practical teaching,can effectively shorten the connection cycle between theoretical teaching and clinical practice by integrating AR technology,improve the clinical practice level of trainee nurses,and provide an innovative model for optimizing the path of clinical nursing talent cultivation.展开更多
Nursing students often exhibit emotional suppression,avoidance,or over-expression when confronted with high-pressure work environments and emotional challenges.These disorders affect nursing students mental health,pro...Nursing students often exhibit emotional suppression,avoidance,or over-expression when confronted with high-pressure work environments and emotional challenges.These disorders affect nursing students mental health,professional adaptation,and quality of communication with patients.The causes of emotional expression difficulties include individual personality,emotional intelligence,educational background,and socio-cultural pressures.To address this issue,it is recommended to enhance nursing students emotional expression and regulation capabilities through psychological interventions,emotional intelligence training,and optimization of educational systems,thereby improving their mental health and career development,ultimately enhancing nursing service quality and doctor-patient relationships.展开更多
Delirium is a transient and acute syndrome of encephalopathy,characterized by disturbances in consciousness,orientation,cognition,perception,and emotional regulation,often accompanied by hallucinations,illusions,psych...Delirium is a transient and acute syndrome of encephalopathy,characterized by disturbances in consciousness,orientation,cognition,perception,and emotional regulation,often accompanied by hallucinations,illusions,psychomotor agitation,and restlessness.Postoperative delirium(POD),a common complication particularly in elderly patients,significantly impacts recovery by prolonging mechanical ventilation,neurosurgical intensive care unit stays,and overall hospitalization durations,while severely diminishing patients’quality of life after discharge.Despite its prevalence,POD remains underrecognized in clinical practice,with significant gaps in its diagnosis and management.This review explores the definition,diagnostic criteria,underlying pathogenesis,and associated risk factors of POD in neurosurgical patients,aiming to offer valuable insights for improving clinical diagnosis and therapeutic strategies.展开更多
Trimethoprim(TMP),as a broad-spectrum bacteriostatic antibiotic,is widely used in clinical anti-infection therapy and livestock breeding.However,its low water solubility leads to insufficient bioavailability,which has...Trimethoprim(TMP),as a broad-spectrum bacteriostatic antibiotic,is widely used in clinical anti-infection therapy and livestock breeding.However,its low water solubility leads to insufficient bioavailability,which has become a key problem restricting its development.Cyclodextrins and their derivatives,with their unique cyclic structures,can form inclusion complexes with TMP to improve its properties.This article reviews the pharmacological characteristics of TMP,the types and properties of common cyclodextrins,focusing on introducing various preparation methods of trimethoprim cyclodextrin inclusion complexes and multiple characterization methods for identifying the inclusion complexes,aiming to provide a reference for further research and development of trimethoprim cyclodextrin inclusion complexes.展开更多
Depression is a prevalent neuropsychiatric disorder characterized by persistent sadness,anhedonia,guilt,fatigue,and impaired concentration.Although pharmacotherapy and psychotherapy can be effective,their utility is l...Depression is a prevalent neuropsychiatric disorder characterized by persistent sadness,anhedonia,guilt,fatigue,and impaired concentration.Although pharmacotherapy and psychotherapy can be effective,their utility is limited by adverse effects and significant inter-individual variability.Non-pharmacological therapies from traditional medicine have emerged as promising adjuncts owing to their favorable safety profiles,minimal side effects,and high patient compliance.These therapies,including acupoint stimulation,meditation,and yoga,produce antidepressant effects by reducing neuroinflammation,modulating neurotransmitter release,enhancing neuroplasticity,and regulating the gut-brain axis.This review summarizes clinical applications and mechanistic insights of traditional medicine’s non-pharmacological therapies for depression,providing a scientific rationale for their integration into comprehensive management.展开更多
Suicide is a major and urgent issue in the field of mental health,and the United Nations has set“reducing global suicide mortality by one third by 2030”as one of its sustainable development goals.Suicide literacy re...Suicide is a major and urgent issue in the field of mental health,and the United Nations has set“reducing global suicide mortality by one third by 2030”as one of its sustainable development goals.Suicide literacy refers to an individual’s ability to recognize,manage,and prevent suicide-related problems.This article offers a comprehensive review of the concepts,assessment tools,factors,and interventions of suicide literacy,with the goal of helping individuals to better understand suicidal behaviors and providing a scientific basis for developing effective suicide prevention strategies and measures to advance the progress of suicide prevention.展开更多
Periodontitis has emerged as one of the most critical oral diseases, and research on this condition holds great importance for the advancement of stomatology. As the most authoritative national scientific research fun...Periodontitis has emerged as one of the most critical oral diseases, and research on this condition holds great importance for the advancement of stomatology. As the most authoritative national scientific research funding institution in China, the National Natural Science Foundation of China (NSFC) has played a pivotal role in driving the progress of periodontal science by supporting research on periodontitis. This article provides a comprehensive review of the research and development progress related to periodontitis in China from 2014 to 2023, highlighting the significant contributions of the NSFC to this field. We have summarized the detailed funding information from the NSFC, including the number of applicant codes, funded programs and the distribution of funded scholars. These data illustrate the efforts of the NSFC in cultivating young scientists and building research groups to address key challenges in national scientific research. This study offers an overview of the current hot topics, recent breakthroughs and future research prospects related to periodontitis in China.展开更多
In recent years,the incidence of type 2 diabetes mellitus(T2DM)caused by obesity in China has been increasing continuously,which has become a risk factor for the onset of T2DM and seriously affects the quality of life...In recent years,the incidence of type 2 diabetes mellitus(T2DM)caused by obesity in China has been increasing continuously,which has become a risk factor for the onset of T2DM and seriously affects the quality of life of patients.The conventional treatment methods include weight loss and regulating the body’s metabolism.Semaglutide,as a glucagon-like peptide-1 receptor agonist(GLP-1RA),mainly reduces patients’appetite,decreases their craving for high-fat and high-sugar foods,regulates hypothalamic feeding behavior,inhibits gastric emptying and gastrointestinal motility,and ultimately leads to weight loss.Metformin mainly acts on extra-islet tissues,increasing glucose utilization,reducing glucose production,and ultimately lowering blood glucose levels.Based on this,this article reviews relevant literature on authoritative websites such as CNKI and Wanfang,organizes the data,and analyzes the research progress of semaglutide combined with metformin in the treatment of obese T2DM.The aim is to bring more treatment options for obese T2DM and promote better prognosis for patients.展开更多
This article focuses on the factors influencing fracture nonunion, classification and treatment. The article emphasizes the importance of understanding the influencing factors and mechanisms of fracture healing for de...This article focuses on the factors influencing fracture nonunion, classification and treatment. The article emphasizes the importance of understanding the influencing factors and mechanisms of fracture healing for developing effective treatment strategies and improving patients’ quality of life. It also points out the challenges of current treatment, such as patient compliance and limitations of treatment methods, and looks at future treatment directions.展开更多
Acute liver failure(ALF),a severe clinical syndrome marked by high mortality rates and limited conventional treatments,urgently requires innovative therapeutic strategies.In recent years,human umbilical cord mesenchym...Acute liver failure(ALF),a severe clinical syndrome marked by high mortality rates and limited conventional treatments,urgently requires innovative therapeutic strategies.In recent years,human umbilical cord mesenchymal stem cells(hUC-MSCs)have emerged as a research hotspot due to their unique differentiation potential,remarkable regenerative capacity,and significant immune regulatory properties.Studies demonstrate that it can improve liver function through multiple mechanisms,promote hepatocyte regeneration,and reduce hepatic injury.Additionally,their role in regulating inflammatory responses provides new therapeutic approaches for ALF.This review systematically examines the latest research progress on hUC-MSCs in ALF treatment,focusing on their mechanisms of action,therapeutic efficacy,and clinical application prospects,aiming to provide valuable references for future research and clinical practice.展开更多
Nursing care during the perioperative period of thyroid cancer plays a crucial role in the recovery of patients.With the development of medical technology,Western medicine nursing techniques have matured in the periop...Nursing care during the perioperative period of thyroid cancer plays a crucial role in the recovery of patients.With the development of medical technology,Western medicine nursing techniques have matured in the perioperative period,including preoperative risk assessment and airway management,intraoperative neuromonitoring nursing coordination,postoperative drainage,and incision management.However,single Western medicine nursing often cannot fully meet the multifaceted needs of patients,especially in emotional nursing and the management of postoperative adverse reactions.The involvement of traditional Chinese medicine nursing techniques provides an effective complement to nursing work.Through integrated Chinese and Western medicine nursing,it is possible not only to improve patients’preoperative anxiety and postoperative nausea and vomiting but also to effectively manage postoperative pain,enhancing the overall comfort and recovery speed of patients.展开更多
This article systematically reviews the research progress on health literacy in lung cancer patients,covering the core definition and multidimensional assessment system of health literacy,epidemiological characteristi...This article systematically reviews the research progress on health literacy in lung cancer patients,covering the core definition and multidimensional assessment system of health literacy,epidemiological characteristics,mechanisms of its impact on clinical outcomes and quality of life,as well as targeted intervention strategies.Research indicates that health literacy significantly improves patient prognosis through pathways such as enhancing treatment adherence,optimizing doctor-patient communication,and strengthening self-management capabilities.This review also points out that future research needs to focus on developing cross-cultural assessment tools,exploring neurocognitive mechanisms,integrating digital technologies,and promoting policy translation to address the new challenges in the era of chronic disease management for lung cancer.展开更多
In recent years,diabetes has posed a serious threat to human health.Traditional Chinese medicine for lowering blood sugar has attracted much attention due to its unique advantages in the treatment of diabetes.This pap...In recent years,diabetes has posed a serious threat to human health.Traditional Chinese medicine for lowering blood sugar has attracted much attention due to its unique advantages in the treatment of diabetes.This paper summarizes the research results on common traditional Chinese medicines for lowering blood sugar in recent years.These results lay a theoretical foundation for the future clinical development and use of hypoglycemic Chinese medicine,the improvement of the quality standards of hypoglycemic Chinese medicine,and the in-depth research on the mechanisms.展开更多
This paper systematically reviews the research progress of Advance Care Planning(ACP)in the field of lung cancer,and discusses its implementation status,key influencing factors and future development direction,includi...This paper systematically reviews the research progress of Advance Care Planning(ACP)in the field of lung cancer,and discusses its implementation status,key influencing factors and future development direction,including deepening of theoretical research,innovation of practice mode,optimization of policy support and cultural adaptation research.展开更多
AIM:To conduct a comprehensive bibliometric analysis of age-related macular degeneration(AMD)research from 2002 to 2022,identifying key contributing countries,institutions,authors,journals,and research hotspots to inf...AIM:To conduct a comprehensive bibliometric analysis of age-related macular degeneration(AMD)research from 2002 to 2022,identifying key contributing countries,institutions,authors,journals,and research hotspots to inform future research directions.METHODS:Publications related to AMD were retrieved from the Web of Science Core Collection(WoSCC)database for the period January 1,2002,to December 31,2022.The search was limited to English-language articles and reviews.Bibliometric analysis was performed using Microsoft Excel 2021 for data management and annual publication analysis.Visualization and network analyses were conducted using VOSviewer,CiteSpace,and the Bibliometrix package in R.Collaboration networks among countries,institutions,authors,and journals were mapped.Keywords were analyzed for co-occurrence to identify research hotspots.Metrics such as H-index,total link strength(TLS),and citation counts were used to assess impact.RESULTS:A total of 16715 publications were analyzed,showing a consistent increase in AMD research output over the past 20y,peaking at 1445 publications in 2021.The United States was the leading contributor with 31.8%of total publications,followed by China and the United Kingdom.The University of Melbourne emerged as the most productive institution with the highest TLS,indicating strong international collaborations.Professor Frank G.Holz was identified as the most influential author based on H-index and publication count.Investigative Ophthalmology&Visual Science was the most prolific journal and had the highest citation impact.Keyword co-occurrence analysis revealed four main research clusters:pathogenesis,therapy,epidemiology,and diagnosis.Emerging research hotspots included anti-vascular endothelial growth factor(VEGF)therapies,optical coherence tomography angiography,and artificial intelligence(AI)applications in diagnosis.CONCLUSION:The bibliometric analysis highlights significant growth and collaborative efforts in AMD research globally.Key contributors have advanced understanding in pathogenesis,therapeutic strategies,epidemiology,and diagnostic technologies.Future research should focus on interdisciplinary collaborations,novel therapeutic targets,personalized medicine,and technological innovations such as AI to effectively address the challenges posed by AMD.展开更多
Type III acute acquired comitant esotropia(AACE)is a special type of binocular coordination disorder with sudden onset characteristics,but its pathogenesis and treatment strategies remain unclear.This article analyzes...Type III acute acquired comitant esotropia(AACE)is a special type of binocular coordination disorder with sudden onset characteristics,but its pathogenesis and treatment strategies remain unclear.This article analyzes the incidence and classification characteristics of Type III AACE,and explores its pathogenesis from multiple perspectives including clinical medicine,neuroscience,and neuro-ophthalmology.It is found that this disease is associated with factors such as decompensation of phoria,dysfunction of the visual center,abnormalities in the physiological and anatomical structure of extraocular muscles,accommodative factors,and disorders of convergence and divergence.The prognosis of Type III AACE is excellent with treatments such as botulinum toxin injection and surgery,and adjunctive therapies like prism adaptation test and visual function training can enhance the management effect.This article provides an in-depth analysis of the pathogenesis and cutting-edge treatment techniques for patients with Type III AACE,which can offer guidance for the subsequent diagnosis and treatment of such patients.展开更多
The integration of Chinese and Western medicine in the treatment of malignant tumors is becoming increasingly widespread.By combining modern medical technology with traditional Chinese medicine,this approach enhances ...The integration of Chinese and Western medicine in the treatment of malignant tumors is becoming increasingly widespread.By combining modern medical technology with traditional Chinese medicine,this approach enhances therapeutic efficacy while reducing side effects.This paper reviews the principles and mechanisms of integrated therapy and analyzes its clinical applications and advantages.Studies indicate that this approach is effective in treating common malignancies such as lung,stomach,and liver cancer,especially in slowing tumor progression,relieving symptoms,and improving patients’quality of life.Chemotherapy combined with Chinese medicine has shown positive effects on survival rates and immune function.However,limitations remain,including insufficient clinical trial data and differences in efficacy across different cancer types,necessitating further high-quality studies.Overall,integrated Chinese and Western medicine offers advantages such as reduced side effects,improved survival rates,and enhanced immune function,providing a comprehensive treatment strategy and a theoretical foundation for its clinical application.展开更多
With the development of modern society,people put forward higher requirements for building safety,which makes the construction project face new challenges.Reinforced concrete frame structure as a common engineering ty...With the development of modern society,people put forward higher requirements for building safety,which makes the construction project face new challenges.Reinforced concrete frame structure as a common engineering type,although the construction technology has been relatively mature,but its earthquake collapse ability still needs to be strengthened.This paper analyzes the specific factors that affect the seismic collapse ability of reinforced concrete frame structure,summarizes the previous research results,and puts forward innovative application of fiber-reinforced polymer(FRP)composite materials,play the role of smart materials,improve the isolation and energy dissipation devices,etc.,to promote the continuous optimization of reinforced concrete frame structure design,and show better seismic performance.展开更多
The development of Meizhou Hakka cuisine relies on the role of professional cooking talents.Higher vocational colleges serve as the platform for cultivating cooking talents.Among various training models,the implementa...The development of Meizhou Hakka cuisine relies on the role of professional cooking talents.Higher vocational colleges serve as the platform for cultivating cooking talents.Among various training models,the implementation of the progressive talent training model featuring the integration of industry and education and work-study alternation is conducive to carrying out talent cultivation activities,improving the effectiveness of professional talent development,and effectively meeting the needs of market development.From the perspective of Meizhou Hakka cuisine cooking talents,this paper analyzes the problems existing in the implementation of the industry-education integration and work-study alternation model,and puts forward specific practical strategies for talent cultivation.The purpose is to enhance the training effect of Hakka cuisine cooking talents and provide reference for the subsequent optimization of professional teaching.展开更多
文摘With the iteration and upgrading of medical technology and the continuous growth of public health demands,the quality of nursing services has become a core indicator for measuring the effectiveness of the medical system.The clinical practice ability of nursing staff is directly related to the safety of patient diagnosis and treatment and the rehabilitation process.However,the current clinical nursing talent training model is facing bottlenecks such as limited practical scenarios and fragmented case cognition.This study focuses on the teaching application of augmented reality(AR)technology in hospital Settings and systematically reviews the research progress on the improvement of clinical practice ability of trainee nurses based on the AR immersive teaching model.By constructing a clinical teaching scenario that integrates virtual and real,AR technology can dynamically simulate complex case handling processes and enhance nursing students’three-dimensional cognition of condition assessment,operation norms,and emergency plans.Hospitals,as the core base for practical teaching,can effectively shorten the connection cycle between theoretical teaching and clinical practice by integrating AR technology,improve the clinical practice level of trainee nurses,and provide an innovative model for optimizing the path of clinical nursing talent cultivation.
基金Supported by National Natural Science Foundation of China(71774049).
文摘Nursing students often exhibit emotional suppression,avoidance,or over-expression when confronted with high-pressure work environments and emotional challenges.These disorders affect nursing students mental health,professional adaptation,and quality of communication with patients.The causes of emotional expression difficulties include individual personality,emotional intelligence,educational background,and socio-cultural pressures.To address this issue,it is recommended to enhance nursing students emotional expression and regulation capabilities through psychological interventions,emotional intelligence training,and optimization of educational systems,thereby improving their mental health and career development,ultimately enhancing nursing service quality and doctor-patient relationships.
基金Supported by Science and Technology Program of Nantong City,No.Key003Nantong Young Medical Expert,No.46+2 种基金the Science and Technology Program of Nantong Health Committee,No.MA2019003,No.MA2021017,and No.MSZ2024038Science and Technology Program of Nantong City,No.JCZ2022040Kangda College of Nanjing Medical University,No.KD2021JYYJYB025,No.KD2022KYJJZD022,and No.KD2024KYJJ289.
文摘Delirium is a transient and acute syndrome of encephalopathy,characterized by disturbances in consciousness,orientation,cognition,perception,and emotional regulation,often accompanied by hallucinations,illusions,psychomotor agitation,and restlessness.Postoperative delirium(POD),a common complication particularly in elderly patients,significantly impacts recovery by prolonging mechanical ventilation,neurosurgical intensive care unit stays,and overall hospitalization durations,while severely diminishing patients’quality of life after discharge.Despite its prevalence,POD remains underrecognized in clinical practice,with significant gaps in its diagnosis and management.This review explores the definition,diagnostic criteria,underlying pathogenesis,and associated risk factors of POD in neurosurgical patients,aiming to offer valuable insights for improving clinical diagnosis and therapeutic strategies.
基金Academic Fund for Students of Foshan University in 2024(Project No.:xsjj202409zrb11)。
文摘Trimethoprim(TMP),as a broad-spectrum bacteriostatic antibiotic,is widely used in clinical anti-infection therapy and livestock breeding.However,its low water solubility leads to insufficient bioavailability,which has become a key problem restricting its development.Cyclodextrins and their derivatives,with their unique cyclic structures,can form inclusion complexes with TMP to improve its properties.This article reviews the pharmacological characteristics of TMP,the types and properties of common cyclodextrins,focusing on introducing various preparation methods of trimethoprim cyclodextrin inclusion complexes and multiple characterization methods for identifying the inclusion complexes,aiming to provide a reference for further research and development of trimethoprim cyclodextrin inclusion complexes.
基金supported by the Beijing Natural Science Foundation(7244491)Beijing TCM Science and Technology Development Fund Project(BJZYON-2023-05)+2 种基金Fundamental Research Funds for the Central Public Welfare Research Institutes(ZZ15-YQ-048,ZZ-YQ2023006)Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(ZYYCXTD-D-202409)Science and Technology Innovation Project of the Institute of Acupuncture and Moxibustion,China Academy of Chinese Medical Sciences(CIZJS2025023).
文摘Depression is a prevalent neuropsychiatric disorder characterized by persistent sadness,anhedonia,guilt,fatigue,and impaired concentration.Although pharmacotherapy and psychotherapy can be effective,their utility is limited by adverse effects and significant inter-individual variability.Non-pharmacological therapies from traditional medicine have emerged as promising adjuncts owing to their favorable safety profiles,minimal side effects,and high patient compliance.These therapies,including acupoint stimulation,meditation,and yoga,produce antidepressant effects by reducing neuroinflammation,modulating neurotransmitter release,enhancing neuroplasticity,and regulating the gut-brain axis.This review summarizes clinical applications and mechanistic insights of traditional medicine’s non-pharmacological therapies for depression,providing a scientific rationale for their integration into comprehensive management.
文摘Suicide is a major and urgent issue in the field of mental health,and the United Nations has set“reducing global suicide mortality by one third by 2030”as one of its sustainable development goals.Suicide literacy refers to an individual’s ability to recognize,manage,and prevent suicide-related problems.This article offers a comprehensive review of the concepts,assessment tools,factors,and interventions of suicide literacy,with the goal of helping individuals to better understand suicidal behaviors and providing a scientific basis for developing effective suicide prevention strategies and measures to advance the progress of suicide prevention.
文摘Periodontitis has emerged as one of the most critical oral diseases, and research on this condition holds great importance for the advancement of stomatology. As the most authoritative national scientific research funding institution in China, the National Natural Science Foundation of China (NSFC) has played a pivotal role in driving the progress of periodontal science by supporting research on periodontitis. This article provides a comprehensive review of the research and development progress related to periodontitis in China from 2014 to 2023, highlighting the significant contributions of the NSFC to this field. We have summarized the detailed funding information from the NSFC, including the number of applicant codes, funded programs and the distribution of funded scholars. These data illustrate the efforts of the NSFC in cultivating young scientists and building research groups to address key challenges in national scientific research. This study offers an overview of the current hot topics, recent breakthroughs and future research prospects related to periodontitis in China.
文摘In recent years,the incidence of type 2 diabetes mellitus(T2DM)caused by obesity in China has been increasing continuously,which has become a risk factor for the onset of T2DM and seriously affects the quality of life of patients.The conventional treatment methods include weight loss and regulating the body’s metabolism.Semaglutide,as a glucagon-like peptide-1 receptor agonist(GLP-1RA),mainly reduces patients’appetite,decreases their craving for high-fat and high-sugar foods,regulates hypothalamic feeding behavior,inhibits gastric emptying and gastrointestinal motility,and ultimately leads to weight loss.Metformin mainly acts on extra-islet tissues,increasing glucose utilization,reducing glucose production,and ultimately lowering blood glucose levels.Based on this,this article reviews relevant literature on authoritative websites such as CNKI and Wanfang,organizes the data,and analyzes the research progress of semaglutide combined with metformin in the treatment of obese T2DM.The aim is to bring more treatment options for obese T2DM and promote better prognosis for patients.
文摘This article focuses on the factors influencing fracture nonunion, classification and treatment. The article emphasizes the importance of understanding the influencing factors and mechanisms of fracture healing for developing effective treatment strategies and improving patients’ quality of life. It also points out the challenges of current treatment, such as patient compliance and limitations of treatment methods, and looks at future treatment directions.
基金Key Project of the Hunan Provincial Department of Education(Project No.:21A0024):Effect of Exosomes Derived from Umbilical Cord Blood MSCs Transfected with VEGF165 Gene on Inflammatory Apoptosis of Hepatocytes in Rats with Acute Liver Failure.
文摘Acute liver failure(ALF),a severe clinical syndrome marked by high mortality rates and limited conventional treatments,urgently requires innovative therapeutic strategies.In recent years,human umbilical cord mesenchymal stem cells(hUC-MSCs)have emerged as a research hotspot due to their unique differentiation potential,remarkable regenerative capacity,and significant immune regulatory properties.Studies demonstrate that it can improve liver function through multiple mechanisms,promote hepatocyte regeneration,and reduce hepatic injury.Additionally,their role in regulating inflammatory responses provides new therapeutic approaches for ALF.This review systematically examines the latest research progress on hUC-MSCs in ALF treatment,focusing on their mechanisms of action,therapeutic efficacy,and clinical application prospects,aiming to provide valuable references for future research and clinical practice.
文摘Nursing care during the perioperative period of thyroid cancer plays a crucial role in the recovery of patients.With the development of medical technology,Western medicine nursing techniques have matured in the perioperative period,including preoperative risk assessment and airway management,intraoperative neuromonitoring nursing coordination,postoperative drainage,and incision management.However,single Western medicine nursing often cannot fully meet the multifaceted needs of patients,especially in emotional nursing and the management of postoperative adverse reactions.The involvement of traditional Chinese medicine nursing techniques provides an effective complement to nursing work.Through integrated Chinese and Western medicine nursing,it is possible not only to improve patients’preoperative anxiety and postoperative nausea and vomiting but also to effectively manage postoperative pain,enhancing the overall comfort and recovery speed of patients.
基金Supported by National Natural Science Foundation of China(71774049).
文摘This article systematically reviews the research progress on health literacy in lung cancer patients,covering the core definition and multidimensional assessment system of health literacy,epidemiological characteristics,mechanisms of its impact on clinical outcomes and quality of life,as well as targeted intervention strategies.Research indicates that health literacy significantly improves patient prognosis through pathways such as enhancing treatment adherence,optimizing doctor-patient communication,and strengthening self-management capabilities.This review also points out that future research needs to focus on developing cross-cultural assessment tools,exploring neurocognitive mechanisms,integrating digital technologies,and promoting policy translation to address the new challenges in the era of chronic disease management for lung cancer.
文摘In recent years,diabetes has posed a serious threat to human health.Traditional Chinese medicine for lowering blood sugar has attracted much attention due to its unique advantages in the treatment of diabetes.This paper summarizes the research results on common traditional Chinese medicines for lowering blood sugar in recent years.These results lay a theoretical foundation for the future clinical development and use of hypoglycemic Chinese medicine,the improvement of the quality standards of hypoglycemic Chinese medicine,and the in-depth research on the mechanisms.
基金Supported by National Natural Science Foundation of China(71774049).
文摘This paper systematically reviews the research progress of Advance Care Planning(ACP)in the field of lung cancer,and discusses its implementation status,key influencing factors and future development direction,including deepening of theoretical research,innovation of practice mode,optimization of policy support and cultural adaptation research.
基金Supported by the National Natural Science Foundation of China(No.82371033)the Tianjin Natural Science Foundation(No.21JCZDJC01250)the Tianjin Key Medical Discipline(Specialty)Construction Project(No.TJYXZDXK-016A).
文摘AIM:To conduct a comprehensive bibliometric analysis of age-related macular degeneration(AMD)research from 2002 to 2022,identifying key contributing countries,institutions,authors,journals,and research hotspots to inform future research directions.METHODS:Publications related to AMD were retrieved from the Web of Science Core Collection(WoSCC)database for the period January 1,2002,to December 31,2022.The search was limited to English-language articles and reviews.Bibliometric analysis was performed using Microsoft Excel 2021 for data management and annual publication analysis.Visualization and network analyses were conducted using VOSviewer,CiteSpace,and the Bibliometrix package in R.Collaboration networks among countries,institutions,authors,and journals were mapped.Keywords were analyzed for co-occurrence to identify research hotspots.Metrics such as H-index,total link strength(TLS),and citation counts were used to assess impact.RESULTS:A total of 16715 publications were analyzed,showing a consistent increase in AMD research output over the past 20y,peaking at 1445 publications in 2021.The United States was the leading contributor with 31.8%of total publications,followed by China and the United Kingdom.The University of Melbourne emerged as the most productive institution with the highest TLS,indicating strong international collaborations.Professor Frank G.Holz was identified as the most influential author based on H-index and publication count.Investigative Ophthalmology&Visual Science was the most prolific journal and had the highest citation impact.Keyword co-occurrence analysis revealed four main research clusters:pathogenesis,therapy,epidemiology,and diagnosis.Emerging research hotspots included anti-vascular endothelial growth factor(VEGF)therapies,optical coherence tomography angiography,and artificial intelligence(AI)applications in diagnosis.CONCLUSION:The bibliometric analysis highlights significant growth and collaborative efforts in AMD research globally.Key contributors have advanced understanding in pathogenesis,therapeutic strategies,epidemiology,and diagnostic technologies.Future research should focus on interdisciplinary collaborations,novel therapeutic targets,personalized medicine,and technological innovations such as AI to effectively address the challenges posed by AMD.
文摘Type III acute acquired comitant esotropia(AACE)is a special type of binocular coordination disorder with sudden onset characteristics,but its pathogenesis and treatment strategies remain unclear.This article analyzes the incidence and classification characteristics of Type III AACE,and explores its pathogenesis from multiple perspectives including clinical medicine,neuroscience,and neuro-ophthalmology.It is found that this disease is associated with factors such as decompensation of phoria,dysfunction of the visual center,abnormalities in the physiological and anatomical structure of extraocular muscles,accommodative factors,and disorders of convergence and divergence.The prognosis of Type III AACE is excellent with treatments such as botulinum toxin injection and surgery,and adjunctive therapies like prism adaptation test and visual function training can enhance the management effect.This article provides an in-depth analysis of the pathogenesis and cutting-edge treatment techniques for patients with Type III AACE,which can offer guidance for the subsequent diagnosis and treatment of such patients.
文摘The integration of Chinese and Western medicine in the treatment of malignant tumors is becoming increasingly widespread.By combining modern medical technology with traditional Chinese medicine,this approach enhances therapeutic efficacy while reducing side effects.This paper reviews the principles and mechanisms of integrated therapy and analyzes its clinical applications and advantages.Studies indicate that this approach is effective in treating common malignancies such as lung,stomach,and liver cancer,especially in slowing tumor progression,relieving symptoms,and improving patients’quality of life.Chemotherapy combined with Chinese medicine has shown positive effects on survival rates and immune function.However,limitations remain,including insufficient clinical trial data and differences in efficacy across different cancer types,necessitating further high-quality studies.Overall,integrated Chinese and Western medicine offers advantages such as reduced side effects,improved survival rates,and enhanced immune function,providing a comprehensive treatment strategy and a theoretical foundation for its clinical application.
文摘With the development of modern society,people put forward higher requirements for building safety,which makes the construction project face new challenges.Reinforced concrete frame structure as a common engineering type,although the construction technology has been relatively mature,but its earthquake collapse ability still needs to be strengthened.This paper analyzes the specific factors that affect the seismic collapse ability of reinforced concrete frame structure,summarizes the previous research results,and puts forward innovative application of fiber-reinforced polymer(FRP)composite materials,play the role of smart materials,improve the isolation and energy dissipation devices,etc.,to promote the continuous optimization of reinforced concrete frame structure design,and show better seismic performance.
基金2025 Meizhou Municipal Planning Project of Philosophy and Social Sciences(Project No.:mzsklx2025101)。
文摘The development of Meizhou Hakka cuisine relies on the role of professional cooking talents.Higher vocational colleges serve as the platform for cultivating cooking talents.Among various training models,the implementation of the progressive talent training model featuring the integration of industry and education and work-study alternation is conducive to carrying out talent cultivation activities,improving the effectiveness of professional talent development,and effectively meeting the needs of market development.From the perspective of Meizhou Hakka cuisine cooking talents,this paper analyzes the problems existing in the implementation of the industry-education integration and work-study alternation model,and puts forward specific practical strategies for talent cultivation.The purpose is to enhance the training effect of Hakka cuisine cooking talents and provide reference for the subsequent optimization of professional teaching.
