Both auto-power spectrum and cross-power spectrum need to be controlled in multi-input multi-output （MIMO） random vibration test. During the control process with the difference control algorithm （DCA）, a lower tri...Both auto-power spectrum and cross-power spectrum need to be controlled in multi-input multi-output （MIMO） random vibration test. During the control process with the difference control algorithm （DCA）, a lower triangular matrix is derived from Cholesky decomposition of a reference spectrum matrix. The diagonal elements of the lower triangular matrix （DELTM） may become negative. These negative values have no meaning in physical significance and can cause divergence of auto-power spectrum control. A proportional root mean square control algorithm （PRMSCA） provides another method to avoid the divergence caused by negative values of DELTM, but PRMSCA cannot control the cross-power spectrum. A new control algorithm named matrix power control algorithm （MPCA） is proposed in the paper. MPCA can guarantee that DELTM is always positive in the auto-power spectrum control. MPCA can also control the cross-power spectrum. After these three control algorithms are analyzed, three-input three-output random vibration control tests are implemented on a three-axis vibration shaker. The results show the validity of the proposed MPCA.展开更多
A control method for Multi-Input Multi-Output（MIMO） non-Gaussian random vibration test with cross spectra consideration is proposed in the paper. The aim of the proposed control method is to replicate the specified ...A control method for Multi-Input Multi-Output（MIMO） non-Gaussian random vibration test with cross spectra consideration is proposed in the paper. The aim of the proposed control method is to replicate the specified references composed of auto spectral densities, cross spectral densities and kurtoses on the test article in the laboratory. It is found that the cross spectral densities will bring intractable coupling problems and induce difficulty for the control of the multioutput kurtoses. Hence, a sequential phase modification method is put forward to solve the coupling problems in multi-input multi-output non-Gaussian random vibration test. To achieve the specified responses, an improved zero memory nonlinear transformation is utilized first to modify the Fourier phases of the signals with sequential phase modification method to obtain one frame reference response signals which satisfy the reference spectra and reference kurtoses. Then, an inverse system method is used in frequency domain to obtain the continuous stationary drive signals. At the same time, the matrix power control algorithm is utilized to control the spectra and kurtoses of the response signals further. At the end of the paper, a simulation example with a cantilever beam and a vibration shaker test are implemented and the results support the proposed method very well.展开更多
OBJECTIVE:To evaluate the effectiveness of a combined Traditional Chinese Medicine(TCM) therapy versus conventional treatment on adolescent idiopathic scoliosis.METHODS:One hundred twenty outpatients with mild and mod...OBJECTIVE:To evaluate the effectiveness of a combined Traditional Chinese Medicine(TCM) therapy versus conventional treatment on adolescent idiopathic scoliosis.METHODS:One hundred twenty outpatients with mild and moderate adolescent idiopathic scoliosis were randomly divided into a TCM group(TCMG)and a brace group(CG).TCMG patients underwent Daoyin,Tuina,and acupotomology therapies.CG patients were treated with a Milwaukee brace.Each patient's Cobb angle was measured after 12 and 24 months of treatment,and pulmonary function was determined after 12 months of treatment.Average electromyogram(AEMG) ratio of the surface electromyogram was measured after 6 and 12 months of treatment and followed-up after 18 and 24 months.RESULTS:The Cobb angle significantly decreased in both groups after 12 months of treatment compared with before treatment(P< 0.05).The percentages of original Cobb angle in TCMG and CG were51.4%and 47.8%(P > 0.05) after 12 months and62.5%and 34.7%(P < 0.05) after 24 months,respectively.Pulmonary function significantly improved after 12 months in TCMG(P < 0.05) but significantly decreased in CG(P < 0.05).The AEMG ratio was significantly lower(P < 0.01) and tended to remain at1 after stopping treatment in TCMG,but increased in CG(P<0.05).CONCLUSION:TCM combined therapy can prevent the progression of scoliosis.The AEMG ratio is a promising index that could replace radiography in the evaluation of treatment effect and progression in scoliosis.展开更多
OBJECTIVE: To assess the efficacy and safety in patients with chronic heart failure(CHF) of Western medication plus Traditional Chinese Medicine(TCM) preparations.METHODS: This prospective, single-blind, randomized, c...OBJECTIVE: To assess the efficacy and safety in patients with chronic heart failure(CHF) of Western medication plus Traditional Chinese Medicine(TCM) preparations.METHODS: This prospective, single-blind, randomized, controlled, and multicenter clinical trial began on September 17, 2008, and was completed on June 25, 2011. A total of 340 inpatients, aged 40-79 years, with exacerbating CHF from 10 hospitals were enrolled and randomly allocated within 24 h of admission. The trial included three intervention periods. During hospitalization, the control group received western medication for CHF and the treatment group received Danhong injection with Shenfu injection or Shenmai injection. After discharge,all patients were treated with Qiliqiangxin capsules and Buyiqiangxin tablets or a placebo for 6 months. After the 6-month intervention, both groups received only continuous western medication. The primary endpoint was all-cause mortality.The efficacy assessments were as follows: B-type natriuretic peptide(BNP), Lee's HF score, the 6-minute walking test(6 MWT), left ventricular ejection fraction(LVEF), and the Minnesota Living with Heart Failure Questionnaire(MLHFQ). The safety assessments were as follows: blood and urine routine examination, hepatic and renal function, electrolytes in blood and adverse events.RESULTS: Compared with the control group, the treatment group showed a 30.99% reduction in all-cause mortality and an improved survival rate.The treatment group showed greater improvement in 6 MWT(P = 0.02) than the control group on discharge, after 12-month follow-up, there was a time-group interaction for MLHFQ(P = 0.03). Incidence rate of adverse events and other relevant safety indexes were not statistically significant between the two groups.CONCLUSION: Western medication plus TCM treatment can increase 6-minute walking distance(improve exercise tolerance) and quality of life with heart failure patients.展开更多
OBJECTIVE： To document the therapeutic effects of Feiwei granules （FGs） for idiopathic pulmonary fi-brosis （IPF）.METHODS： One hundred cases with IPF were ran- domized into the treatment group （80） and control ...OBJECTIVE： To document the therapeutic effects of Feiwei granules （FGs） for idiopathic pulmonary fi-brosis （IPF）.METHODS： One hundred cases with IPF were ran- domized into the treatment group （80） and control group （20）. Both groups were given basic treat- ment with prednisone. The treatment group was given FGs, and the control group was given Jinshui- bao capsules （JCs）. Treatment lasted for 6 months. The Medical Research Council Dyspnea Scale （MRCDS）, the Saint George＇s Hospital Respiratory Questionnaire （SGHRQ）, pulmonary function, the Traditional Chinese Medicine Syndrome Score （TC- MSS）, 6-min walking test （6MWT） and blood gas analyses were recorded before the study as well as 3 months and 6 months after treatment.RESULTS： FGs showed greater efficacy than the control in certain parameters between before the study and 6 months, and between 3 months and 6 months, in the MRCDS, some indicators in the SGHRQ, and the TCMSS. There were no significant differences between the treatment group and con- trol group in the remainder of the indices evaluat- ed. In the treatment group, there were significant differences in before and after treatment in the MRCDS, SGHRQ, TCMSS and 6MWT.展开更多
OBJECTIVE:To systematically evaluate the curative effect of acupuncture on post-stroke depression(PSD).METHODS:The internet was used to retrieve the Wanfang Medical Data System,Chinese Periodical Net,the Weipu Informa...OBJECTIVE:To systematically evaluate the curative effect of acupuncture on post-stroke depression(PSD).METHODS:The internet was used to retrieve the Wanfang Medical Data System,Chinese Periodical Net,the Weipu Information Resources System,PubMed and the Cochrane Library Database.Relevant articles,up to September 2010,were manually retrieved.These papers included studies that had performed random and semi-random control trials for the use of acupuncture to treat PSD.Fifteen random control tests involving 1096 patients were included in this study and individual cases,interventional measures and curative effects were extracted from this research.Grade methodological quality evaluation and meta-analysis were performed on these studies.RESULTS:Comparison between the acupuncture group and the Western medicine group for the curative rate on PSD revealed an OR of 1.48,95% CI = [1.11 1.97] and P=0.008.Comparison of obviously effective rate shows that OR=1.39,95% CI=[1.08 1.80] and P=0.01.Comparison of effective rate showsthatOR=0.83,95%CI=[0.631.09]andP=0.18.CONCLUSION:Comparison between the acupuncture group and Western medicine group in treating PSD revealed that there is a statistical difference in curative rate and remarkably effective rate,but no difference in effective rate.展开更多
目的本文试图通过对近半个世纪以来运动处方的产生及其发展过程,以及各阶段的特点进行分析和评价,为运动处方、运动康复疗法和机能评定在我国的普及应用提供理论和实践依据。方法采用计算机网络文献和资料收集法,对Medlin via Ovid、Pub...目的本文试图通过对近半个世纪以来运动处方的产生及其发展过程,以及各阶段的特点进行分析和评价,为运动处方、运动康复疗法和机能评定在我国的普及应用提供理论和实践依据。方法采用计算机网络文献和资料收集法,对Medlin via Ovid、PubMed、Sport Discus、CINAHL、CAM、EMbase和EBM Cochrane Databaseof SR 7个数据库进行检索,检索词为exercise prescription、physical tness、exercise therapy、tness assessment、exercise test、randomized,检索时间均从建库至2008年6月。然后对其中的随机和非随机对照研究,以及资料较全者纳入分析讨论。结果共检索到318篇文献,但其中涉及运动处方和机能评定的随机对照试验(RCT)仅有7篇,系统评价和Meta分析各1篇。我们对其中资料较全又有代表性的93篇文献进行了系统分析讨论。结果显示:最早的运动处方和机能评定研究可以追溯到1950年,其发展与运动康复疗法的发展密不可分。二十世纪70年代是运动处方发展的初始期,首先是在身体活动与心血管健康方面提出了运动处方的概念,而后逐步提出了针对个体的运动处方,进而开始把运动处方与体能测试联系在一起讨论。二十世纪80年代运动处方开始进入了全面发展的阶段,开始用体能测试指导运动处方,并使运动处方和机能评定进入实验阶段。二十世纪90年代运动处方开始与多种运动康复疗法相结合,针对多种疾病进行干预和治疗,并与多种体能训练方法相结合指导训练和康复,成为一种主要的非药物治疗手段。进入本世纪以后,运动处方和机能评定的研究得到了全面提高,开始出现非随机对照试验和RCT,一些先进的测试手段和分析方法开始应用于机能评定和运动处方的实施。结论运动处方的发展与运动康复疗法和运动机能评定的发展是密不可分的,机能评定和体能测试是执行和实施运动处方的基础。当今,运动处方已从单一的体育锻炼方法提高到了针对多种疾病的非药物治疗手段。运动处方和机能评定的科学化已从观察性研究、群体研究,开始进入了非随机对照试验和RCT。相对其它生物学科而言,运动处方的RCT研究相对滞后,如何使运动处方获得最大的益处和最低的风险仍是值得研究的问题。展开更多
基金National Natural Science Foundation of China （10972104） The Fundamental Research Funds for NUAA（NS2010007）
文摘Both auto-power spectrum and cross-power spectrum need to be controlled in multi-input multi-output （MIMO） random vibration test. During the control process with the difference control algorithm （DCA）, a lower triangular matrix is derived from Cholesky decomposition of a reference spectrum matrix. The diagonal elements of the lower triangular matrix （DELTM） may become negative. These negative values have no meaning in physical significance and can cause divergence of auto-power spectrum control. A proportional root mean square control algorithm （PRMSCA） provides another method to avoid the divergence caused by negative values of DELTM, but PRMSCA cannot control the cross-power spectrum. A new control algorithm named matrix power control algorithm （MPCA） is proposed in the paper. MPCA can guarantee that DELTM is always positive in the auto-power spectrum control. MPCA can also control the cross-power spectrum. After these three control algorithms are analyzed, three-input three-output random vibration control tests are implemented on a three-axis vibration shaker. The results show the validity of the proposed MPCA.
基金supported by the Priority Academic Program Development of Jiangsu Higher Education Institutionsthe Postgraduate Research & Practice Innovation Program of Jiangsu Province (No. KYCX17_0234)
文摘A control method for Multi-Input Multi-Output（MIMO） non-Gaussian random vibration test with cross spectra consideration is proposed in the paper. The aim of the proposed control method is to replicate the specified references composed of auto spectral densities, cross spectral densities and kurtoses on the test article in the laboratory. It is found that the cross spectral densities will bring intractable coupling problems and induce difficulty for the control of the multioutput kurtoses. Hence, a sequential phase modification method is put forward to solve the coupling problems in multi-input multi-output non-Gaussian random vibration test. To achieve the specified responses, an improved zero memory nonlinear transformation is utilized first to modify the Fourier phases of the signals with sequential phase modification method to obtain one frame reference response signals which satisfy the reference spectra and reference kurtoses. Then, an inverse system method is used in frequency domain to obtain the continuous stationary drive signals. At the same time, the matrix power control algorithm is utilized to control the spectra and kurtoses of the response signals further. At the end of the paper, a simulation example with a cantilever beam and a vibration shaker test are implemented and the results support the proposed method very well.
基金Supported by Outstanding Youth Fund of the Administration of Traditional Chinese Medicine of Zhejiang Province,China(No.2012ZQ011)
文摘OBJECTIVE:To evaluate the effectiveness of a combined Traditional Chinese Medicine(TCM) therapy versus conventional treatment on adolescent idiopathic scoliosis.METHODS:One hundred twenty outpatients with mild and moderate adolescent idiopathic scoliosis were randomly divided into a TCM group(TCMG)and a brace group(CG).TCMG patients underwent Daoyin,Tuina,and acupotomology therapies.CG patients were treated with a Milwaukee brace.Each patient's Cobb angle was measured after 12 and 24 months of treatment,and pulmonary function was determined after 12 months of treatment.Average electromyogram(AEMG) ratio of the surface electromyogram was measured after 6 and 12 months of treatment and followed-up after 18 and 24 months.RESULTS:The Cobb angle significantly decreased in both groups after 12 months of treatment compared with before treatment(P< 0.05).The percentages of original Cobb angle in TCMG and CG were51.4%and 47.8%(P > 0.05) after 12 months and62.5%and 34.7%(P < 0.05) after 24 months,respectively.Pulmonary function significantly improved after 12 months in TCMG(P < 0.05) but significantly decreased in CG(P < 0.05).The AEMG ratio was significantly lower(P < 0.01) and tended to remain at1 after stopping treatment in TCMG,but increased in CG(P<0.05).CONCLUSION:TCM combined therapy can prevent the progression of scoliosis.The AEMG ratio is a promising index that could replace radiography in the evaluation of treatment effect and progression in scoliosis.
基金Supported by National Key Technology R&D Programs in the 11th Five-Year Plan of China:Study on Comprehensive Evaluation Method of Integral Effect of Traditional Chinese Medicine Treatment for Heart Failure(No.2006BAI08B02-01)Ministry of Education of People's Republic of China"Program for Innovative Research Team in University"–Research on TCM for the Prevention and Treatment of Cardiovascular Diseases(No.IRT_16R54)Tianjin Science and Technology Program:Tianjin TCM Clinical Medicine Research Center(No.15ZXLCSY00020)
文摘OBJECTIVE: To assess the efficacy and safety in patients with chronic heart failure(CHF) of Western medication plus Traditional Chinese Medicine(TCM) preparations.METHODS: This prospective, single-blind, randomized, controlled, and multicenter clinical trial began on September 17, 2008, and was completed on June 25, 2011. A total of 340 inpatients, aged 40-79 years, with exacerbating CHF from 10 hospitals were enrolled and randomly allocated within 24 h of admission. The trial included three intervention periods. During hospitalization, the control group received western medication for CHF and the treatment group received Danhong injection with Shenfu injection or Shenmai injection. After discharge,all patients were treated with Qiliqiangxin capsules and Buyiqiangxin tablets or a placebo for 6 months. After the 6-month intervention, both groups received only continuous western medication. The primary endpoint was all-cause mortality.The efficacy assessments were as follows: B-type natriuretic peptide(BNP), Lee's HF score, the 6-minute walking test(6 MWT), left ventricular ejection fraction(LVEF), and the Minnesota Living with Heart Failure Questionnaire(MLHFQ). The safety assessments were as follows: blood and urine routine examination, hepatic and renal function, electrolytes in blood and adverse events.RESULTS: Compared with the control group, the treatment group showed a 30.99% reduction in all-cause mortality and an improved survival rate.The treatment group showed greater improvement in 6 MWT(P = 0.02) than the control group on discharge, after 12-month follow-up, there was a time-group interaction for MLHFQ(P = 0.03). Incidence rate of adverse events and other relevant safety indexes were not statistically significant between the two groups.CONCLUSION: Western medication plus TCM treatment can increase 6-minute walking distance(improve exercise tolerance) and quality of life with heart failure patients.
基金Supported by the Special Scientific Research for Traditional Chinese Medicine of State Administration of Traditional Chinese Medicine of China:Effects of Feiwei Granules in the treatment of IPF(No.200807046)
文摘OBJECTIVE： To document the therapeutic effects of Feiwei granules （FGs） for idiopathic pulmonary fi-brosis （IPF）.METHODS： One hundred cases with IPF were ran- domized into the treatment group （80） and control group （20）. Both groups were given basic treat- ment with prednisone. The treatment group was given FGs, and the control group was given Jinshui- bao capsules （JCs）. Treatment lasted for 6 months. The Medical Research Council Dyspnea Scale （MRCDS）, the Saint George＇s Hospital Respiratory Questionnaire （SGHRQ）, pulmonary function, the Traditional Chinese Medicine Syndrome Score （TC- MSS）, 6-min walking test （6MWT） and blood gas analyses were recorded before the study as well as 3 months and 6 months after treatment.RESULTS： FGs showed greater efficacy than the control in certain parameters between before the study and 6 months, and between 3 months and 6 months, in the MRCDS, some indicators in the SGHRQ, and the TCMSS. There were no significant differences between the treatment group and con- trol group in the remainder of the indices evaluat- ed. In the treatment group, there were significant differences in before and after treatment in the MRCDS, SGHRQ, TCMSS and 6MWT.
文摘为了验证汽车控制器在车辆上抵抗振动的能力,随机振动试验必不可少。合理的工装设计能保证随机振动输入载荷准确地被传递到控制器上。传统的工装设计只考虑其第1阶模态频率大于功率谱密度(Power Spectral Density,PSD)载荷的最大频率,以防止在振动过程中出现共振,而忽略了振动传递特性的影响,从而导致控制器在进行随机振动试验时出现过试验的情况。针对这一问题,对某款汽车控制器的工装振动特性进行了有限元仿真和试验。仿真和试验结果表明:不仅工装的模态要满足要求,同时要保证工装安装控制器螺栓孔处的主轴均方根(Root Mean Square,RMS)加速度偏差在±20%以内,此时工装可以比较准确地将振动台载荷传递给控制器,从而满足设计要求。
基金Supported by Specific scientific research fund for doctoral points of higher learning institutions of Education Ministry,20094425110005State natural science fund,30772828+1 种基金Guangdong provincial natural science fund,07004846Project in sci-tech plan of sci-tech department of Guangdong province,2008B030301206
文摘OBJECTIVE:To systematically evaluate the curative effect of acupuncture on post-stroke depression(PSD).METHODS:The internet was used to retrieve the Wanfang Medical Data System,Chinese Periodical Net,the Weipu Information Resources System,PubMed and the Cochrane Library Database.Relevant articles,up to September 2010,were manually retrieved.These papers included studies that had performed random and semi-random control trials for the use of acupuncture to treat PSD.Fifteen random control tests involving 1096 patients were included in this study and individual cases,interventional measures and curative effects were extracted from this research.Grade methodological quality evaluation and meta-analysis were performed on these studies.RESULTS:Comparison between the acupuncture group and the Western medicine group for the curative rate on PSD revealed an OR of 1.48,95% CI = [1.11 1.97] and P=0.008.Comparison of obviously effective rate shows that OR=1.39,95% CI=[1.08 1.80] and P=0.01.Comparison of effective rate showsthatOR=0.83,95%CI=[0.631.09]andP=0.18.CONCLUSION:Comparison between the acupuncture group and Western medicine group in treating PSD revealed that there is a statistical difference in curative rate and remarkably effective rate,but no difference in effective rate.
