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长链非编码RNA TUG1通过调节miR-145影响宫颈癌发生发展机制研究
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作者 迪丽达尔·斯地克 王华芳 胡尔西旦·尼牙孜 《中国实验诊断学》 2026年第1期119-122,共4页
目的探讨长链非编码RNA TUG1在调控miR-145表达水平的作用,分析其对于宫颈癌发生发展机制的影响。方法选取2020年1月到2023年12月新疆医科大学第一附属医院患者宫颈癌组织及细胞株,通过RT-PCR实验和qRT-PCR实验,检测长链非编码RNA TUG1... 目的探讨长链非编码RNA TUG1在调控miR-145表达水平的作用,分析其对于宫颈癌发生发展机制的影响。方法选取2020年1月到2023年12月新疆医科大学第一附属医院患者宫颈癌组织及细胞株,通过RT-PCR实验和qRT-PCR实验,检测长链非编码RNA TUG1、miR-145的表达水平,进行siRNA转染、CCK-8细胞增殖检测、Annexin V-FITC流式细胞术实验以及细胞克隆形成实验,分析si-TUG1、anti-miR-145对宫颈癌细胞株的增殖、凋亡及放射照射敏感性的影响。结果在si-TUG1+anti-miR-145组中,患者放疗后宫颈癌细胞OD值、存活率更低。TUG1的表达水平越低,miR-145表达水平越高,在TUG1低表达、miR-145高表达的情况下,宫颈癌细胞的凋亡率越高。结论miR-145的表达水平是影响宫颈癌发生发展的重要因素,长链非编码RNA TUG1对miR-145的表达水平具有调控作用,两者呈负调控关系,能够为疾病的诊治提供有价值的参考依据。 展开更多
关键词 长链非编码RNA TUG1 调节mir-145 宫颈癌
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lncRNA FGD5-AS1靶向miR-512-3p/RAB31抑制膀胱癌细胞增殖、侵袭和上皮-间质转化
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作者 李富博 李爱科 +5 位作者 饶井芬 刘宝兴 石方玉 李文鑫 杨春丽 林萍萍 《中国医科大学学报》 北大核心 2026年第1期33-40,共8页
目的探讨长链非编码RNA(lncRNA)FGD5反义RNA 1(FGD5-AS1)、miR-512-3p和Ras相关蛋白31(RAB31)在膀胱癌进展中的作用和调控机制。方法收集2019年1月至2021年12月于承德医学院附属医院行手术治疗的60例膀胱癌患者肿瘤组织及癌旁组织,并体... 目的探讨长链非编码RNA(lncRNA)FGD5反义RNA 1(FGD5-AS1)、miR-512-3p和Ras相关蛋白31(RAB31)在膀胱癌进展中的作用和调控机制。方法收集2019年1月至2021年12月于承德医学院附属医院行手术治疗的60例膀胱癌患者肿瘤组织及癌旁组织,并体外培养膀胱癌细胞系(5637、KU-19-19、T24、UM-UC-3)和正常尿路上皮细胞系(SV-HUC-1)。采用实时定量PCR检测肿瘤组织和癌旁组织以及膀胱癌细胞中FGD5-AS1、miR-512-3p和RAB31 mRNA表达,Pearson相关分析确定膀胱癌患者癌组织中miR-512-3p与FGD5-AS1、RAB31 mRNA表达之间的相关性。将sh-NC、sh-FGD5-AS1、sh-FGD5-AS1和NC抑制剂、sh-FGD5-AS1和miR-512-3p抑制剂转染至T24细胞中,分别记为阴性对照组、FGD5-AS1沉默组、抑制剂对照组、联合组;另设置正常组(不转染)。用CCK-8法检测细胞活力;Transwell小室测定细胞迁移和侵袭能力;Western blotting检测RAB31和E-钙黏蛋白(E-cadherin)、N-钙黏蛋白(N-cadherin)、波形蛋白(vimentin)表达;双萤光素酶报告基因和RNA Pull down实验检测miR-512-3p与FGD5-AS1和RAB31的靶向关系。结果膀胱癌组织与细胞中FGD5-AS1、RAB31 mRNA呈高表达,miR-512-3p呈低表达(P<0.05),且膀胱癌患者癌组织中FGD5-AS1、RAB31 m RNA的表达与mi R-512-3p表达呈负相关,FGD5-AS1与RAB31 mRNA表达呈正相关(r=-0.779、-0.649、0.652,均P<0.001)。沉默FGD5-AS1可上调miR-512-3p表达,下调RAB31 mRNA和蛋白表达,降低细胞活力、迁移和侵袭数以及N-cadherin、vimentin水平,升高E-cadherin水平(P<0.05);敲低miR-512-3p表达可明显减弱沉默FGD5-AS1对膀胱癌T24细胞增殖、迁移和侵袭以及上皮-间质转化(EMT)进程的抑制作用(P<0.05);FGD5-AS1可以海绵化miR-512-3p,而RAB31是miR-512-3p的靶标。结论沉默FGD5-AS1可能通过上调miR-512-3p、下调RAB31表达抑制膀胱癌细胞的增殖、迁移、侵袭和EMT进程。 展开更多
关键词 膀胱癌 增殖 上皮-间质转化 长链非编码RNA FGD5-AS1 mir-512-3p/Ras相关蛋白31
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JOINT ITERATIVE DECODING FOR SIMPLE-ENCODING SYSTEMATIC IRREGULAR-LDPC-BASED CODED COOPERATION IN NON-IDEAL RELAY CHANNEL 被引量:3
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作者 Chen Jingwen Yang Fengfan +1 位作者 Luo Lin Tho Le-Ngoc 《Journal of Electronics(China)》 2010年第3期305-315,共11页
In this paper, a new kind of simple-encoding irregular systematic LDPC codes suitable for one-relay coded cooperation is designed, where the proposed joint iterative decoding is effectively performed in the destinatio... In this paper, a new kind of simple-encoding irregular systematic LDPC codes suitable for one-relay coded cooperation is designed, where the proposed joint iterative decoding is effectively performed in the destination which is in accordance with the corresponding joint Tanner graph characterizing two different component LDPC codes used by the source and relay in ideal and non-ideal relay cooperations. The theoretical analysis and simulations show that the coded cooperation scheme obviously outperforms the coded non-cooperation one under the same code rate and decoding complex. The significant performance improvement can be virtually credited to the additional mutual exchange of the extrinsic information resulted by the LDPC code employed by the source and its counterpart used by the relay in both ideal and non-ideal cooperations. 展开更多
关键词 Cooperative communication Low-density parity-check code Relay channel Joint Tanner graph Joint iterative decoding
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血清lncRNA MEG3、miR-181b-5p结合PSA水平评估前列腺癌包膜侵犯及根治性前列腺切除术预后的价值
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作者 李月峰 刘涛 +3 位作者 王伟 张珑 王海东 黄海乔 《中华男科学杂志》 2026年第1期15-20,共6页
目的研究血清长链非编码RNA母系表达基因3(lncRNA MEG3)、微小核糖核酸-181b-5p(miR-181b-5p)结合前列腺特异性抗原(PSA)水平评估前列腺癌(PCa)包膜侵犯及根治性前列腺切除术预后的临床价值。方法选择邯郸市第一医院泌尿外科2017年8月至... 目的研究血清长链非编码RNA母系表达基因3(lncRNA MEG3)、微小核糖核酸-181b-5p(miR-181b-5p)结合前列腺特异性抗原(PSA)水平评估前列腺癌(PCa)包膜侵犯及根治性前列腺切除术预后的临床价值。方法选择邯郸市第一医院泌尿外科2017年8月至2020年8月收治的96例PCa患者为PCa组,同期收治的50例良性前列腺增生患者为对照组,采用RT-PCR法及免疫层析法检测两组血清中lncRNA MEG3、miR-181b-5p及PSA水平,采用ROC曲线分析血清lncRNA MEG3、miR-181b-5p及PSA单独或联合对PCa的诊断价值。分析血清lncRNA MEG3、miR-181b-5p、PSA表达水平与PCa患者临床病理特征的关系,采用Spearman检验分析PCa患者血清lncRNA MEG3、miR-181b-5p、PSA水平与包膜侵犯的相关性,采用Cox回归模型分析根治性前列腺切除术预后的影响因素,采用Kaplan-Meier曲线分析lncRNA MEG3、miR-181b-5p、PSA表达水平不同者3年总生存率。结果PCa组血清lncRNA MEG3显著低于对照组(P<0.05),血清miR-181b-5p、PSA显著高于对照组(P<0.05)。ROC曲线显示,血清lncRNA MEG3、miR-181b-5p及PSA单独或联合诊断PCa的AUC(95%CI)分别为0.723(0.635~0.815)、0.764(0.675~0.852)、0.811(0.739~0.891)、0.920(0.870~0.974),联合诊断的效力显著优于单项检测(P<0.05)。与Gleason评分<7分、临床分期Ⅰ+Ⅱ期、未发生淋巴结转移、未发生包膜侵犯、组织中高分化者比较,Gleason评分≥7分、临床分期Ⅲ期、发生淋巴结转移、发生包膜侵犯、组织低分化者血清lncRNA MEG3水平显著降低(P<0.05),血清miR-181b-5p、PSA水平显著升高(P<0.05)。PCa患者血清lncRNA MEG3水平与包膜侵犯呈负相关(P<0.05),血清miR-181b-5p、PSA水平与包膜侵犯呈正相关(P<0.05)。lncRNA MEG3低水平组3年总生存率明显低于lncRNA MEG3高水平组,miR-181b-5p、PSA高水平组3年总生存率明显低于miR-181b-5p、PSA低水平组(P<0.05)。lncRNA MEG3降低、miR-181b-5p升高、PSA升高、临床分期Ⅲ期、包膜侵犯、淋巴结转移是根治性前列腺切除术预后的危险因素(P<0.05)。结论PCa患者血清中lncRNA MEG3呈低表达,miR-181b-5p和PSA呈高表达,且与包膜侵犯、3年总生存率降低相关,有望为PCa早期诊断、病情评估及预后判断提供一定参考。 展开更多
关键词 血清 长链非编码RNA母系表达基因3 微小核糖核酸-181b-5p 前列腺特异抗原 前列腺癌 包膜侵犯 总生存率
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补肝散调节R-spondin1/Wnt3a介导的肠道损伤改善D-半乳糖致衰老大鼠消化吸收功能障碍 被引量:1
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作者 王翼轩 霍冉 +4 位作者 田津 方芳 刘娜 王杰鹏 方朝义 《中国实验方剂学杂志》 北大核心 2025年第9期19-27,共9页
目的:基于R-脊椎蛋白1(R-spondin1)/Wnt3a信号途径探讨衰老大鼠消化吸收功能变化与肝虚状态关系及补肝散作用特点。方法:SPF级SD雄性大鼠48只,随机分为空白组,模型组,补肝散低、中、高剂量组,维生素E组,各8只。除空白组腹腔注射生理盐水... 目的:基于R-脊椎蛋白1(R-spondin1)/Wnt3a信号途径探讨衰老大鼠消化吸收功能变化与肝虚状态关系及补肝散作用特点。方法:SPF级SD雄性大鼠48只,随机分为空白组,模型组,补肝散低、中、高剂量组,维生素E组,各8只。除空白组腹腔注射生理盐水外,其余各组均腹腔注射D-半乳糖(400 mg·kg^(-1))制备衰老大鼠模型。造模当日起,补肝散低、中、高(7.03、14.06、28.12 g·kg^(-1))剂量组分别灌胃相应剂量水煎液,维生素E组灌胃维生素E混悬液(27 mg·kg^(-1)),空白组和模型组灌胃等量生理盐水(10 mL·kg^(-1))。观察大鼠皮毛色泽、活动情况、体质量、饮水量及摄食量等一般生物学表征变化,结合血清丙二醛(MDA)含量及超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)活性以评估大鼠衰老状态;测定抓力及血清总胆汁酸(TBA)含量和α-淀粉酶(AMY)活性,以评测大鼠肝气虚损状态;测定十二指肠组织β-半乳糖苷酶(β-gal)活性以评价肠道衰老情况,检测血清胰高血糖素样肽-1(GLP-1)、血管活性肽(VIP)和D-木糖含量以评估消化吸收功能;苏木素-伊红(HE)染色观察大鼠十二指肠病理形态以评估肠道损伤状态;免疫组化染色观察十二指肠B细胞特异性莫洛尼鼠白血病病毒整合位点1(Bmi1)、富含亮氨酸重复序列的G蛋白偶联受体5(Lgr5)表达特征,实时荧光定量聚合酶链式反应(Real-time PCR)检测十二指肠肿瘤增殖细胞核抗原(Ki67)、Bmi1和Lgr5 mRNA表达,以评估增殖与再生情况;Real-time PCR检测十二指肠组织R-spondin1、Wnt3a、β-连环蛋白(β-catenin)、糖原合成酶激酶-3β(GSK-3β)mRNA表达,蛋白免疫印迹法(Western blot)测定十二指肠组织R-spondin1、Wnt3a、β-catenin、p-GSK-3β蛋白表达,以分析衰老大鼠消化吸收功能障发生机制及补肝散作用特点。结果:与空白组比较,模型组大鼠体质量、饮水量、摄食量、抓力及血清SOD、GSH-Px、AMY活性及GLP-1、VIP、D-木糖含量明显降低(P<0.05),血清MDA、TBA含量及十二指肠组织β-gal活性明显升高(P<0.05);十二指肠肠绒毛长度、绒毛宽度、隐窝深度、绒毛/隐窝值(V/C值),Ki67、Lgr5、Bmi1、R-spondin1、Wnt3a、β-catenin mRNA及蛋白表达水平明显降低(P<0.05),GSK-3β、磷酸化(p)-GSK-3β表达明显升高(P<0.05)。与模型组比较,各用药组大鼠体质量、饮水量、摄食量、抓力及血清SOD、GSHPx、AMY活性和GLP-1、VIP、D-木糖含量明显升高(P<0.05),血清MDA、TBA含量及十二指肠组织β-gal活性明显降低(P<0.05);十二指肠肠绒毛长度、绒毛宽度、隐窝深度、V/C值,Ki67、Lgr5、Bmi1、R-spondin1、Wnt3a、β-catenin mRNA及蛋白表达水平明显升高(P<0.05),GSK-3β、p-GSK-3β蛋白表达水平明显降低(P<0.05)。结论:衰老大鼠在肝气虚损状态下呈现出明显的消化吸收功能减退,补益肝气法可通过调节R-spondin1/Wnt3a信号途径改善衰老大鼠肠道衰老损伤,进而增强机体消化吸收功能,从而达到延缓衰老之目的。 展开更多
关键词 衰老 消化吸收功能障碍 r-脊椎蛋白1(r-spondin1)/Wnt3a信号通路 肝气虚损 补肝散
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NEW ITERATIVE SUPER-TRELLIS DECODING WITH SOURCE A PRIORI INFORMATION FOR VLCS WITH TURBO CODES 被引量:3
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作者 Liu Jianjun Tu Guofang Wu Weiren 《Journal of Electronics(China)》 2007年第1期122-127,共6页
A novel Joint Source and Channel Decoding (JSCD) scheme for Variable Length Codes (VLCs) concatenated with turbo codes utilizing a new super-trellis decoding algorithm is presented in this letter. The basic idea of ou... A novel Joint Source and Channel Decoding (JSCD) scheme for Variable Length Codes (VLCs) concatenated with turbo codes utilizing a new super-trellis decoding algorithm is presented in this letter. The basic idea of our decoding algorithm is that source a priori information with the form of bit transition probabilities corresponding to the VLC tree can be derived directly from sub-state transitions in new composite-state represented super-trellis. A Maximum Likelihood (ML) decoding algorithm for VLC sequence estimations based on the proposed super-trellis is also described. Simu-lation results show that the new iterative decoding scheme can obtain obvious encoding gain especially for Reversible Variable Length Codes (RVLCs),when compared with the classical separated turbo decoding and the previous joint decoding not considering source statistical characteristics. 展开更多
关键词 Joint Source and Channel Decoding (JSCD) Variable Length Codes (VLCs) Turbo codes Super-trellis
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坛紫菜R-藻红蛋白的提取纯化及草甘膦检测应用
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作者 黄海钊 赵逸凡 +3 位作者 叶庆琳 李蒙 吴夏泠 张玉苍 《中国食品学报》 北大核心 2026年第1期305-314,共10页
目的:草甘膦是一种常见的除草剂,常残留于水体中,对环境和人体产生危害,开发高效且准确的检测方法,测定水体中的草甘膦含量有重要意义。本研究基于坛紫菜中的R-藻红蛋白设计一种荧光开启型探针,用于水中草甘膦的检测。方法:通过冻融循... 目的:草甘膦是一种常见的除草剂,常残留于水体中,对环境和人体产生危害,开发高效且准确的检测方法,测定水体中的草甘膦含量有重要意义。本研究基于坛紫菜中的R-藻红蛋白设计一种荧光开启型探针,用于水中草甘膦的检测。方法:通过冻融循环和超声破碎提取坛紫菜中的藻红蛋白并进行纯化。肽指纹图谱、吸收光谱和SDS-PAGE测定结果表明,该产物为R-藻红蛋白。本研究方法获得的R-藻红蛋白纯度高达4.96,达到分析纯级。进一步研究发现,提取的R-藻红蛋白对Cu^(2+)离子表现出优异的特异性荧光响应性。基于该特性设计一种基于铜离子猝灭R-藻红蛋白荧光的探针,利用草甘膦与铜离子螯合的特性实现对草甘膦的检测。结果:该探针的荧光信号与草甘膦浓度呈现良好的线性关系,其最低响应值为443.4μg/L,远低于国标《生活饮用水卫生标准》(GB 5749—2022)中草甘膦残留物质量浓度的最大限度(0.7 mg/L)。将该探针用于2种实际水样中草甘膦含量的加样回收检验,检出不同含量的草甘膦。结论:本研究为高纯度R-藻红蛋白提取提供了新思路,为检测水体中草甘膦残留提供了一种新方法,具有一定的科学意义和应用价值。 展开更多
关键词 坛紫菜 r-藻红蛋白 铜离子 草甘膦 加标回收
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Homomorphic Error-Control Codes for Linear Network Coding in Packet Networks
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作者 Xiaodong Han Fei Gao 《China Communications》 SCIE CSCD 2017年第9期178-189,共12页
In this work, the homomorphism of the classic linear block code in linear network coding for the case of binary field and its extensions is studied. It is proved that the classic linear error-control block code is hom... In this work, the homomorphism of the classic linear block code in linear network coding for the case of binary field and its extensions is studied. It is proved that the classic linear error-control block code is homomorphic network error-control code in network coding. That is, if the source packets at the source node for a linear network coding are precoded using a linear block code, then every packet flowing in the network regarding to the source satisfies the same constraints as the source. As a consequence, error detection and correction can be performed at every intermediate nodes of multicast flow, rather than only at the destination node in the conventional way, which can help to identify and correct errors timely at the error-corrupted link and save the cost of forwarding error-corrupted data to the destination node when the intermediate nodes are ignorant of the errors. In addition, three examples are demonstrated which show that homomorphic linear code can be combined with homomorphic signature, McEliece public-key cryptosystem and unequal error protection respectively and thus have a great potential of practical utility. 展开更多
关键词 NETWORK coding NETWORK errorcorrection homomorphic LINEAR CODE multi-cast
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Research on deep learning decoding method for polar codes in ACO-OFDM spatial optical communication system
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作者 LIU Kangrui LI Ming +2 位作者 CHEN Sizhe QU Jiashun ZHOU Ming’ou 《Optoelectronics Letters》 2025年第7期427-433,共7页
Aiming at the problem that the bit error rate(BER)of asymmetrically clipped optical orthogonal frequency division multiplexing(ACO-OFDM)space optical communication system is significantly affected by different turbule... Aiming at the problem that the bit error rate(BER)of asymmetrically clipped optical orthogonal frequency division multiplexing(ACO-OFDM)space optical communication system is significantly affected by different turbulence intensities,the deep learning technique is proposed to the polarization code decoding in ACO-OFDM space optical communication system.Moreover,this system realizes the polarization code decoding and signal demodulation without frequency conduction with superior performance and robustness compared with the performance of traditional decoder.Simulations under different turbulence intensities as well as different mapping orders show that the convolutional neural network(CNN)decoder trained under weak-medium-strong turbulence atmospheric channels achieves a performance improvement of about 10^(2)compared to the conventional decoder at 4-quadrature amplitude modulation(4QAM),and the BERs for both 16QAM and 64QAM are in between those of the conventional decoder. 展开更多
关键词 frequency conduction polar codes deep learning signal demodulation deep learning technique DEcoding ACO OFDM polarization code decoding
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ASME Code Case 3029高温许用压应力计算方法的介绍及工程应用
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作者 马忠明 《化工设备与管道》 北大核心 2026年第1期24-30,共7页
介绍了高温蠕变工况下运行的压力容器可能出现的失效模式,结合工程设计现状,指出了我国当前压力容器标准体系在确定高温蠕变工况许用压应力时存在的技术瓶颈,在此基础之上引出ASME Code Case 3029,对其适用范围、发展历程、产生背景及... 介绍了高温蠕变工况下运行的压力容器可能出现的失效模式,结合工程设计现状,指出了我国当前压力容器标准体系在确定高温蠕变工况许用压应力时存在的技术瓶颈,在此基础之上引出ASME Code Case 3029,对其适用范围、发展历程、产生背景及工程意义进行了简单的介绍,以某工程设计项目中的实际结构为例,介绍了该方法的使用过程及注意事项,并结合压力容器工程设计领域的实际需求,对我国标准体系下一步的制定或修订方向提出了展望。 展开更多
关键词 Code Case 3029 蠕变屈曲 失稳 压力容器 许用应力
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ChatGPT+VS Code在高中地理地图开发中的应用——以“国内人口迁移”为例
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作者 王凌宇 白絮飞 《中国信息技术教育》 2026年第1期81-84,共4页
人工智能技术在中学地理教学中的应用是大势所趋。当前的研究主要聚焦于其作为学生的“助学者”和教师的“助教者”两大角色。然而,现有应用方式存在一定局限性:作为“助学者”,若学生使用不当可能引发依赖性,削弱其独立思考能力;作为... 人工智能技术在中学地理教学中的应用是大势所趋。当前的研究主要聚焦于其作为学生的“助学者”和教师的“助教者”两大角色。然而,现有应用方式存在一定局限性:作为“助学者”,若学生使用不当可能引发依赖性,削弱其独立思考能力;作为“助教者”,若教师生成教学设计的指令过于宽泛,结果易出现“张冠李戴”或“似是而非”等问题,需教师二次加工。相反,若教师能针对教学设计中的特定模块提供详细准确的指令,人工智能技术输出的结果将更具准确性和实用性,展现出更高研究价值。因此,本文从人工智能技术“助教者”身份出发,摒弃传统完整的教学过程设计,聚焦备课中的“地图开发”模块,采用由人工智能技术生成地图代码并通过第三方软件运行的方式,实现快速辅助教师生成所需地图的目标,提升备课效率与教学质量。 展开更多
关键词 ChatGPT VS Code 人工智能技术 中学地理 地图开发
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Full Diversity Reception Based on Dempster-Shafer Theory for Network Coding with Multiple-Antennas Relay 被引量:1
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作者 SUN Yanhua YANG Yi +1 位作者 LI Yonghua ZHANG Yanhua 《China Communications》 SCIE CSCD 2015年第10期76-90,共15页
In this paper,a two-way relay system which achieves bi-directional communication via a multiple-antenna relay in two time slots is studied.In the multiple access(MA) phase,the novel receive schemes based on Dempster-S... In this paper,a two-way relay system which achieves bi-directional communication via a multiple-antenna relay in two time slots is studied.In the multiple access(MA) phase,the novel receive schemes based on Dempster-Shafer(D-S) evidence theory are proposed at the relay node.Instead of traditional linear detection,the first proposed MIMO-DS NC scheme adopts D-S evidence theory to detect the signals of each source node before mapping them into network-coded signal.Moreover,different from traditional physical-layer network coding(PNC) based on virtual MIMO model,the further proposed MIMO-DS PNC comes from the vector space perspective and combines PNC mapping with D-S theory to obtain network-coded signal without estimating each source node signal.D-S theory can appropriately characterize uncertainty and make full use of multiple evidence source information by Dempster's combination rule to obtain reliable decisions.In the broadcast(BC) phase,the space-time coding(STC) and antenna selection(AS) schemes are adopted to achieve transmit diversity.Simulation results reveal that the STC and AS schemes both achieve full transmit diversity in the BC phase and the proposed MIMO-DS NC/PNC schemes obtain better end-to-end BER performance and throughputs compared with traditional schemes with a little complexity increasing and no matter which scheme is adopted in the BC phase,MIMO-DS PNC always achieves full end-to-end diversity gain as MIMO-ML NC but with a lower complexity and its throughput approaches the throughput of MIMO-ML NC in high SNR regime. 展开更多
关键词 network coding MIMO-DS NC/PNC Dempster-shafer evidence theory twoway multiple antennas relay system
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A graph neural network and multi-task learning-based decoding algorithm for enhancing XZZX code stability in biased noise
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作者 Bo Xiao Zai-Xu Fan +2 位作者 Hui-Qian Sun Hong-Yang Ma Xing-Kui Fan 《Chinese Physics B》 2025年第5期250-257,共8页
Quantum error correction is a technique that enhances a system’s ability to combat noise by encoding logical information into additional quantum bits,which plays a key role in building practical quantum computers.The... Quantum error correction is a technique that enhances a system’s ability to combat noise by encoding logical information into additional quantum bits,which plays a key role in building practical quantum computers.The XZZX surface code,with only one stabilizer generator on each face,demonstrates significant application potential under biased noise.However,the existing minimum weight perfect matching(MWPM)algorithm has high computational complexity and lacks flexibility in large-scale systems.Therefore,this paper proposes a decoding method that combines graph neural networks(GNN)with multi-classifiers,the syndrome is transformed into an undirected graph,and the features are aggregated by convolutional layers,providing a more efficient and accurate decoding strategy.In the experiments,we evaluated the performance of the XZZX code under different biased noise conditions(bias=1,20,200)and different code distances(d=3,5,7,9,11).The experimental results show that under low bias noise(bias=1),the GNN decoder achieves a threshold of 0.18386,an improvement of approximately 19.12%compared to the MWPM decoder.Under high bias noise(bias=200),the GNN decoder reaches a threshold of 0.40542,improving by approximately 20.76%,overcoming the limitations of the conventional decoder.They demonstrate that the GNN decoding method exhibits superior performance and has broad application potential in the error correction of XZZX code. 展开更多
关键词 quantum error correction XZZX code biased noise graph neural network
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Low Complexity Successive Cancellation List Decoding of U-UV Codes
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作者 Chen Wenhao Chen Li +1 位作者 Lin Jingyu Zhang Huazi 《China Communications》 2025年第1期41-60,共20页
Constituted by BCH component codes and its ordered statistics decoding(OSD),the successive cancellation list(SCL)decoding of U-UV structural codes can provide competent error-correction performance in the short-to-med... Constituted by BCH component codes and its ordered statistics decoding(OSD),the successive cancellation list(SCL)decoding of U-UV structural codes can provide competent error-correction performance in the short-to-medium length regime.However,this list decoding complexity becomes formidable as the decoding output list size increases.This is primarily incurred by the OSD.Addressing this challenge,this paper proposes the low complexity SCL decoding through reducing the complexity of component code decoding,and pruning the redundant SCL decoding paths.For the former,an efficient skipping rule is introduced for the OSD so that the higher order decoding can be skipped when they are not possible to provide a more likely codeword candidate.It is further extended to the OSD variant,the box-andmatch algorithm(BMA),in facilitating the component code decoding.Moreover,through estimating the correlation distance lower bounds(CDLBs)of the component code decoding outputs,a path pruning(PP)-SCL decoding is proposed to further facilitate the decoding of U-UV codes.In particular,its integration with the improved OSD and BMA is discussed.Simulation results show that significant complexity reduction can be achieved.Consequently,the U-UV codes can outperform the cyclic redundancy check(CRC)-polar codes with a similar decoding complexity. 展开更多
关键词 ordered statistics decoding successive cancellation list decoding U-UV codes
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Computation-Efficient Decoding of LDPC Codes for High-Speed Space Laser Communications
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作者 Hu Zhuojun Chen Zhao +1 位作者 Kuang Linling Yin Liuguo 《China Communications》 2025年第12期108-123,共16页
Space laser communication(SLC)is an emerging technology to support high-throughput data transmissions in space networks.In this paper,to guarantee the reliability of high-speed SLC links,we aim at practical implementa... Space laser communication(SLC)is an emerging technology to support high-throughput data transmissions in space networks.In this paper,to guarantee the reliability of high-speed SLC links,we aim at practical implementation of low-density paritycheck(LDPC)decoding under resource-restricted space platforms.Particularly,due to the supply restriction and cost issues of high-speed on-board devices such as analog-to-digital converters(ADCs),the input of LDPC decoding will be usually constrained by hard-decision channel output.To tackle this challenge,density-evolution-based theoretical analysis is firstly performed to identify the cause of performance degradation in the conventional binaryinitialized iterative decoding(BIID)algorithm.Then,a computation-efficient decoding algorithm named multiary-initialized iterative decoding with early termination(MIID-ET)is proposed,which improves the error-correcting performance and computation efficiency by using a reliability-based initialization method and a threshold-based decoding termination rule.Finally,numerical simulations are conducted on example codes of rates 7/8 and 1/2 to evaluate the performance of different LDPC decoding algorithms,where the proposed MIID-ET outperforms the BIID with a coding gain of 0.38 dB and variable node calculation saving of 37%.With this advantage,the proposed MIID-ET can notably reduce LDPC decoder’s hardware implementation complexity under the same bit error rate performance,which successfully doubles the total throughput to 10 Gbps on a single-chip FPGA. 展开更多
关键词 computation-efficient decoding highspeed decoders LDPC codes LLR initialization space laser communications
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Enhancement of Error-Correction Coding of Spatial Watermarks in Gray Code
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作者 Tadahiko Kimoto 《Journal of Signal and Information Processing》 2013年第1期57-63,共7页
This paper demonstrates how channel coding can improve the robustness of spatial image watermarks against signal distortion caused by lossy data compression such as the JPEG scheme by taking advantage of the propertie... This paper demonstrates how channel coding can improve the robustness of spatial image watermarks against signal distortion caused by lossy data compression such as the JPEG scheme by taking advantage of the properties of Gray code. Two error-correction coding (ECC) schemes are used here: One scheme, referred to as the vertical ECC (VECC), is to encode information bits in a pixel by error-correction coding where the Gray code is used to improve the performance. The other scheme, referred to as the horizontal ECC (HECC), is to encode information bits in an image plane. In watermarking, HECC generates a codeword representing watermark bits, and each bit of the codeword is encoded by VECC. Simple single-error-correcting block codes are used in VECC and HECC. Several experiments of these schemes were conducted on test images. The result demonstrates that the error-correcting performance of HECC just depends on that of VECC, and accordingly, HECC enhances the capability of VECC. Consequently, HECC with appropriate codes can achieve stronger robustness to JPEG—caused distortions than non-channel-coding watermarking schemes. 展开更多
关键词 ERROr-CORRECTION coding GRAY Code Digital WATERMARK SPATIAL Domain JPEG DCT Compression
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Spatial Image Watermarking by Error-Correction Coding in Gray Codes
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作者 Tadahiko Kimoto 《Journal of Signal and Information Processing》 2013年第3期259-273,共15页
In this paper, error-correction coding (ECC) in Gray codes is considered and its performance in the protecting of spatial image watermarks against lossy data compression is demonstrated. For this purpose, the differen... In this paper, error-correction coding (ECC) in Gray codes is considered and its performance in the protecting of spatial image watermarks against lossy data compression is demonstrated. For this purpose, the differences between bit patterns of two Gray codewords are analyzed in detail. On the basis of the properties, a method for encoding watermark bits in the Gray codewords that represent signal levels by a single-error-correcting (SEC) code is developed, which is referred to as the Gray-ECC method in this paper. The two codewords of the SEC code corresponding to respective watermark bits are determined so as to minimize the expected amount of distortion caused by the watermark embedding. The stochastic analyses show that an error-correcting capacity of the Gray-ECC method is superior to that of the ECC in natural binary codes for changes in signal codewords. Experiments of the Gray-ECC method were conducted on 8-bit monochrome images to evaluate both the features of watermarked images and the performance of robustness for image distortion resulting from the JPEG DCT-baseline coding scheme. The results demonstrate that, compared with a conventional averaging-based method, the Gray-ECC method yields watermarked images with less amount of signal distortion and also makes the watermark comparably robust for lossy data compression. 展开更多
关键词 GRAY CODE Error-Correcting CODE Digital WATERMARK Spatial Domain JPEG DCT-Based Compression
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HIGH-PERFORMANCE SIMPLE-ENCODING GENERATOR-BASED SYSTEMATIC IRREGULAR LDPC CODES AND RESULTED PRODUCT CODES
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作者 Yang Fengfan Ye Ming Luo Lin 《Journal of Electronics(China)》 2007年第5期613-621,共9页
Low-Density Parity-Check (LDPC) code is one of the most exciting topics among the coding theory community.It is of great importance in both theory and practical communications over noisy channels.The most advantage of... Low-Density Parity-Check (LDPC) code is one of the most exciting topics among the coding theory community.It is of great importance in both theory and practical communications over noisy channels.The most advantage of LDPC codes is their relatively lower decoding complexity compared with turbo codes,while the disadvantage is its higher encoding complexity.In this paper,a new ap- proach is first proposed to construct high performance irregular systematic LDPC codes based on sparse generator matrix,which can significantly reduce the encoding complexity under the same de- coding complexity as that of regular or irregular LDPC codes defined by traditional sparse parity-check matrix.Then,the proposed generator-based systematic irregular LDPC codes are adopted as con- stituent block codes in rows and columns to design a new kind of product codes family,which also can be interpreted as irregular LDPC codes characterized by graph and thus decoded iteratively.Finally, the performance of the generator-based LDPC codes and the resultant product codes is investigated over an Additive White Gaussian Noise (AWGN) and also compared with the conventional LDPC codes under the same conditions of decoding complexity and channel noise. 展开更多
关键词 LDPC code Iterative decoding Parity-check Generator matrix Product code GRAPH Kronecker product
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Neural network-based decoding for bias-tailored quantum codes over quantum channels with asymmetric noise
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作者 Jihao Fan Qianhui Zhang +1 位作者 Zhihua Zhang Jun Li 《Communications in Theoretical Physics》 2025年第12期32-42,共11页
To improve the decoding performance of quantum error-correcting codes in asymmetric noise channels,a neural network-based decoding algorithm for bias-tailored quantum codes is proposed.The algorithm consists of a bias... To improve the decoding performance of quantum error-correcting codes in asymmetric noise channels,a neural network-based decoding algorithm for bias-tailored quantum codes is proposed.The algorithm consists of a biased noise model,a neural belief propagation decoder,a convolutional optimization layer,and a multi-objective loss function.The biased noise model simulates asymmetric error generation,providing a training dataset for decoding.The neural network,leveraging dynamic weight learning and a multi-objective loss function,mitigates error degeneracy.Additionally,the convolutional optimization layer enhances early-stage convergence efficiency.Numerical results show that for bias-tailored quantum codes,our decoder performs much better than the belief propagation(BP)with ordered statistics decoding(BP+OSD).Our decoder achieves an order of magnitude improvement in the error suppression compared to higher-order BP+OSD.Furthermore,the decoding threshold of our decoder for surface codes reaches a high threshold of 20%. 展开更多
关键词 quantum error correction quantum channels asymmetric noise neural networkbased decoding bias-tailored quantum codes
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LncRNA-14238/TLR-7信号通路参与腰椎间盘突出症痛觉高敏的机制研究
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作者 张磊 白明生 喻新祥 《颈腰痛杂志》 2026年第1期13-18,共6页
目的 探讨长链非编码核糖核酸-14238(LncRNA-14238)/Toll样受体-7(TLR-7)信号通路参与腰椎间盘突出症(LDH)痛觉高敏的机制。方法 68只雄性Sprague-Dawley大鼠分为正常组、LDH组和小干扰长链非编码核糖核酸(si LncRNA)组,采用自体髓核植... 目的 探讨长链非编码核糖核酸-14238(LncRNA-14238)/Toll样受体-7(TLR-7)信号通路参与腰椎间盘突出症(LDH)痛觉高敏的机制。方法 68只雄性Sprague-Dawley大鼠分为正常组、LDH组和小干扰长链非编码核糖核酸(si LncRNA)组,采用自体髓核植入左侧L5/L6神经根旁构建LDH模型,正常组仅行手术操作但不植入髓核,高通量测序检测LncRNA-14238的表达,此外,通过疼痛行为测试、承重实验和旋转杆分析检测LDH模型的痛觉高敏反应,实时荧光定量聚合酶链反应(qRT-PCR)和蛋白质印迹检测LncRNA-14238、TLR-7和内源性酶胱硫氨酸-β合成酶(CBS)的表达。结果 与正常组相比,LncRNA-14238、TLR-7和CBS在LDH组中表达升高,si LncRNA组的LncRNA-14238、TLR-7和CBS表达降低;LDH组的痛觉高敏反应增加,而沉默LncRNA-14238降低了LDH组的痛觉高敏反应,差异有统计学意义(P<0.05)。结论 LncRNA-14238/TLR-7信号通路可能参与LDH痛觉高敏反应。 展开更多
关键词 长链非编码核糖核酸-14238 Toll样受体-7 腰椎间盘突出症 痛觉高敏反应 内源性酶胱硫氨酸-β合成酶 高通量测序
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