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Application of 3D Printing Technology in Oral Implant Dentistry and Its Impact on Bite Force and Masticatory Efficiency
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作者 Fei Chen Jingke Liu 《Journal of Clinical and Nursing Research》 2025年第12期92-98,共7页
Objective:To analyze the impact of 3D printing technology application on bite force and masticatory efficiency in patients following oral implant dentistry treatment.Methods:A total of 84 patients with single-tooth de... Objective:To analyze the impact of 3D printing technology application on bite force and masticatory efficiency in patients following oral implant dentistry treatment.Methods:A total of 84 patients with single-tooth defects,selected from 100 patients who sought treatment from May 2023 to March 2025 and met the study criteria,were included in this study.The patients were divided into groups using a random number table method.The control group(42 cases)received conventional oral implant treatment,while the observation group(42 cases)underwent oral implant treatment guided by 3D printing technology.Both groups were followed up continuously for 6 months postoperatively.Masticatory efficiency,bite force,implantation accuracy indicators,and the incidence of treatment complications were compared between the two groups before treatment and 6 months after treatment.Results:There was no statistically significant difference in the incidence of complications following oral implantation between the two groups(p>0.05).Compared to the control group,the observation group showed increased masticatory efficiency and bite force after oral implant treatment,with statistically significant differences in the deviation values of the implant crown,apical part in the sagittal plane,axial angle,and neck(p<0.05).Conclusion:The application of 3D printing technology in oral implant treatment can effectively reduce implant placement deviations,enhance implantation accuracy,and effectively correct and maintain the oral occlusal force and masticatory function health of patients. 展开更多
关键词 Oral implant 3d printing technology Occlusal force Masticatory efficiency
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Superiority of Strontium-Doped Barium Titanate as an Electron Transport for Perovskite Solar Cells for Enhanced Efficiency and Thermal Stability
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作者 Minhaz Mahmood Mohammad Tariqul Islam +7 位作者 Md Samiul Islam Sakhr M.Sultan Kashfia Noor M.A.Islam K.Sopian Abdullah Alghafis Mohd Adib Ibrahim K.Sobayel 《Transactions of Tianjin University》 2025年第1期42-63,共22页
This study presents a detailed comparative analysis of three electron transport layer(ETL)materials for perovskite solar cells(PSCs),namely titanium dioxide(TiO_(2)),barium titanate(BaTiO_(3)or BTO),and strontium-dope... This study presents a detailed comparative analysis of three electron transport layer(ETL)materials for perovskite solar cells(PSCs),namely titanium dioxide(TiO_(2)),barium titanate(BaTiO_(3)or BTO),and strontium-doped barium titan-ate(Ba_(1−x)Sr_(x)TiO_(3)or BST),and their impact on the quantum efficiency(QE)and power conversion efficiency(PCE)of CH_(3)NH_(3)PbI_(3)(MAPbI_(3))PSCs.The optimized structure demonstrates that devices utilizing BST as an ETL achieved the highest PCE of 29.85%,exhibiting superior thermal stability with the lowest temperature coefficient of−0.43%/K.This temperature-induced degradation is comparable to that of commercially available silicon cells.Furthermore,BST-based ETLs show 29.50%and 26.48%higher PCE than those of TiO_(2)-based and BTO-based ETLs.The enhanced internal QE and favorable current density–voltage(J–V)characteristics of BST compared with those of TiO_(2)and BTO are attributed to its improved charge carrier separation,reduced recombination rates,and robust electrical characteristics under varied environmental conditions.Furthermore,the electric field and generation rate of the BST-based ETLs show a more favorable distribution than those of the TiO_(2)-based and BTO-based ETLs.These findings provide significant insights into the role of different ETLs in enhancing QE,indicating that BST is a superior ETL that enhances both the efficiency and stability of PSCs.This study contributes to the understanding of how perovskite-structured ETLs can be used to design and optimize highly efficient and stable photovoltaic devices. 展开更多
关键词 Perovskite solar cell Electron transport layer Light management Quantum efficiency SCAPS-1d Lumerical FdTd Barium titanate
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Photochemical Efficiency of PSⅡ and Membrane Lipid Peroxidation in Leaves of indica and japonica Rice (Oryza sativa) Under Chilling Temperature and Strong Light Stress Conditions 被引量:18
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作者 季本华 朱素琴 焦德茂 《Acta Botanica Sinica》 CSCD 2002年第2期139-146,共8页
Relationships between fluorescence parameters and membrane lipid peroxidation in leaves of indica and japonica rice (Oryza sativa L.) during later growth stage were studied under chilling temperature and strong light ... Relationships between fluorescence parameters and membrane lipid peroxidation in leaves of indica and japonica rice (Oryza sativa L.) during later growth stage were studied under chilling temperature and strong light stress conditions. Results showed that D1 protein contents of PSⅡ in photosynthetic apparatus dropped, the generation of antheraxanthin (A) and zeaxanthin (Z) of xanthophyll cycle were inhibited partly, PSⅡ photochemical efficiency (F v/F m)and non-photochemical quenching (q N) were also decreased obviously. In addition, endogenous active oxygen scavenger—superoxide dismutase (SOD) reduced, superoxide anion radical (O -· 2) and malondialdehyde (MDA) accumulated, as a result, photooxidation of leaves occurred under chilling temperature and strong light stress conditions. Obvious differences in the changes of the above mentioned physiological parameters between indica and japonica rice were observed. Experiments in leaves treated with inhibitors under chilling temperature and strong light conditions showed that indica rice was more sensitive to chilling temperature with strong light and subjected to photooxidation more than japonica rice. Notable positive correlation between D1 protein contents and F v/F m or (A+Z)/(A+Z+V), and a marked negative correlation between F v/F m and MDA contents were obtained by regression analysis in indica and japonica rice during chilling temperature and strong light conditions. According to the facts mentioned above, it was inferred that PSⅡ photochemical efficiency(F v/F m) was the key index to forecast for the prediction of photooxidation under stress circumstances and the physiological basis were the synthetic capacity of D1 protein and the protection of xanthophyll cycle. 展开更多
关键词 d1 protein PSⅡ photochemical efficiency (F v/F m) membrane lipid peroxidation xanthophyll cycle rICE
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Highly efficient contact detection strategy of 3D discontinuous deformation analysis in continuous-discontinuous simulation
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作者 Jingyu Kang Xiaodong Fu +5 位作者 Qian Sheng Xing Wang Haifeng Ding Xuehan Zhao Tian Xi Shangwei Jiang 《Journal of Rock Mechanics and Geotechnical Engineering》 2025年第11期6977-6992,共16页
Contact detection is the most time-consuming stage in 3D discontinuous deformation analysis(3D-DDA)computation.Improving the efficiency of 3D-DDA is beneficial for its application in large-scale computing.In this stud... Contact detection is the most time-consuming stage in 3D discontinuous deformation analysis(3D-DDA)computation.Improving the efficiency of 3D-DDA is beneficial for its application in large-scale computing.In this study,aiming at the continuous-discontinuous simulation of 3D-DDA,a highly efficient contact detection strategy is proposed.Firstly,the global direct search(GDS)method is integrated into the 3D-DDA framework to address intricate contact scenarios.Subsequently,all geometric elements,including blocks,faces,edges,and vertices are divided into searchable and unsearchable parts.Contacts between unsearchable geometric elements would be directly inherited,while only searchable geometric elements are involved in contact detection.This strategy significantly reduces the number of geometric elements involved in contact detection,thereby markedly enhancing the computation efficiency.Several examples are adopted to demonstrate the accuracy and efficiency of the improved 3D-DDA method.The rock pillars with different mesh sizes are simulated under self-weight.The deformation and stress are consistent with the analytical results,and the smaller the mesh size,the higher the accuracy.The maximum speedup ratio is 38.46 for this case.Furthermore,the Brazilian splitting test on the discs with different flaws is conducted.The results show that the failure pattern of the samples is consistent with the results obtained by other methods and experiments,and the maximum speedup ratio is 266.73.Finally,a large-scale impact test is performed,and approximately 3.2 times enhanced efficiency is obtained.The proposed contact detection strategy significantly improves efficiency when the rock has not completely failed,which is more suitable for continuous-discontinuous simulation. 展开更多
关键词 3d discontinuous deformation analysis Contact detection Computation efficiency Continuous-discontinuous simulation FrACTUrE
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Energy Efficiency and Spectrum Efficiency in Underlay Device-to-Device Communications Enabled Cellular Networks 被引量:6
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作者 Yan Cai Yiyang Ni +2 位作者 Jun Zhang Su Zhao Hongbo Zhu 《China Communications》 SCIE CSCD 2019年第4期16-34,共19页
In this paper, we investigate the energy efficiency and spectrum efficiency, including one-hop device-to-device(D2D) communications mode and two-way amplify-and-forward(AF) relaying D2D communications mode in underlay... In this paper, we investigate the energy efficiency and spectrum efficiency, including one-hop device-to-device(D2D) communications mode and two-way amplify-and-forward(AF) relaying D2D communications mode in underlay D2D communications enabled cellular networks. An analysis of average energy efficiency and spectrum efficiency are developed and closed-form expressions are obtained for two types of D2D communications modes under the effect of Rayleigh fading channel, path loss, and co-channel interference. Analytical results are validated through numerical simulations. Based on the simulation, the effects of the interference, the distance between D2D pair and the position of relay node on the energy efficiency and spectrum efficiency of D2D communications are investigated. The optimal D2D transmission powers of these two modes to maximize the energy efficiency are also investigated. 展开更多
关键词 d2d COMMUNICATIONS energyefficiency SPECTrUM efficiency two-way AMPLIFY-ANd-FOrWArd rELAYING PrOTOCOL
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Discussion on the sweep efficiency of hybrid steam-chemical process in heavy oil reservoirs: An experimental study 被引量:3
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作者 Xiao-Hu Dong Xiu-Chao Jiang +5 位作者 Wei Zheng Hui-Qing Liu Ren-Jie Liu Wu-Chao Wang De-Shang Zeng Tai-Chao Wang 《Petroleum Science》 SCIE CAS CSCD 2022年第6期2905-2921,共17页
Non-condensable gas(NCG),foam and surfactant are the three commonly-used additives in hybrid steam-chemical processes for heavy oil reservoirs.Their application can effectively control the steam injection profile and ... Non-condensable gas(NCG),foam and surfactant are the three commonly-used additives in hybrid steam-chemical processes for heavy oil reservoirs.Their application can effectively control the steam injection profile and increase the sweep efficiency.In this paper,the methods of microscale visualized experiment and macroscale 3D experiment are applied to systematically evaluate the areal and vertical sweep efficiencies of different hybrid steam-chemical processes.First,a series of static tests are performed to evaluate the effect of different additives on heavy oil properties.Then,by a series of tests on the microscale visualized model,the areal sweep efficiencies of a baseline steam flooding process and different follow-up hybrid EOR processes are obtained from the collected 2D images.Specifically,they include the hybrid steam-N_(2)process,hybrid steam-N2/foam process,hybrid steam-surfactant process and hybrid steam-N2/foam/surfactant process(N2/foam slug first and steam-surfactant co-injection then).From the results of static tests and visualized micromodels,the pore scale EOR mechanisms and the difference between them can be discussed.For the vertical sweep efficiencies,a macroscale 3D experiment of steam flooding process and a follow-up hybrid EOR process is conducted.Thereafter,combing the macroscale 3D experiment and laboratory-scaled numerical simulation,the vertical and overall sweep efficiencies of different hybrid steam-chemical processes are evaluated.Results indicate that compared with a steam flooding process,the areal sweep efficiency of a hybrid steam-N2process is lower.It is caused by the high mobility ratio in a steam-N2-heavy oil system.By contrast,the enhancement of sweep efficiency by a hybrid steam-N2/foam/surfactant process is the highest.It is because of the high resistance capacity of NCG foam system and the performance of surfactant.Specifically,a surfactant can interact with the oil film in chief zone and reduce the interfacial energy,and thus the oil droplets/films formed during steam injection stage are unlocked.For NCG foam,it can plug the chief steam flow zone and thus the subsequent injected steam is re-directed.Simultaneously,from the collected 2D images,it is also observed that the reservoir microscopic heterogeneity can have an important effect on their sweep efficiencies.From the 3D experiment and laboratory-scaled numerical simulation,it is found that a N2/foam slug can increase the thermal front angle by about 150 and increase the vertical sweep efficiency by about 26%.Among the four processes,a multiple hybrid EOR process(steam-N2/foam/surfactant process) is recommended than the other ones.This paper provides a novel method to systematically evaluate the sweep efficiency of hybrid steam-chemical process and some new insights on the mechanisms of sweep efficiency enhancement are also addressed.It can benefit the expansion of hybrid steam-chemical processes in the post steamed heavy oil reservoirs. 展开更多
关键词 Heavy oil reservoirs Visualized model Scaled 3d model Sweep efficiency Hybrid EOr process Multicomponent and multiphase fluids
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A hierarchical salt-rejection strategy for sustainable and high-efficiency solar-driven desalination 被引量:1
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作者 Zhengyi Mao Xuliang Chen +7 位作者 Yingxian Chen Junda Shen Jianpan Huang Yuhan Chen Xiaoguang Duan Yicheng Han Kannie Wai Yan Chan Jian LU 《Nano Materials Science》 EI CAS CSCD 2024年第1期38-43,共6页
Solar steam generation(SSG)is widely regarded as one of the most sustainable technologies for seawater desalination.However,salt fouling severely compromises the evaporation performance and lifetime of evaporators,lim... Solar steam generation(SSG)is widely regarded as one of the most sustainable technologies for seawater desalination.However,salt fouling severely compromises the evaporation performance and lifetime of evaporators,limiting their practical applications.Herein,we propose a hierarchical salt-rejection(HSR)strategy to prevent salt precipitation during long-term evaporation while maintaining a rapid evaporation rate,even in high-salinity brine.The salt diffusion process is segmented into three steps—insulation,branching diffusion,and arterial transport—that significantly enhance the salt-resistance properties of the evaporator.Moreover,the HSR strategy overcomes the tradeoff between salt resistance and evaporation rate.Consequently,a high evaporation rate of 2.84 kg m^(-2) h^(-1),stable evaporation for 7 days cyclic tests in 20 wt%NaCl solution,and continuous operation for 170 h in natural seawater under 1 sun illumination were achieved.Compared with control evaporators,the HSR evaporator exhibited a>54%enhancement in total water evaporation mass during 24 h continuous evaporation in 20 wt%salt water.Furthermore,a water collection device equipped with the HSR evaporator realized a high water purification rate(1.1 kg m^(-2) h^(-1)),highlighting its potential for agricultural applications. 展开更多
关键词 Solar water evaporation 3d printing Salt-rejection Hierarchical structures High efficiency
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Investigating the Efficiency Coefficient of Pile Group in Clay Under Two-Way Lateral Load 被引量:1
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作者 Kooshyar Fadayi ASIABSARY Navid HADIANI +1 位作者 Amir Hossein EGHBALI Seyed Mohammad Ali SADREDDINI 《China Ocean Engineering》 SCIE EI CSCD 2023年第5期819-828,共10页
This research investigates the behavior of a 2×2 pile group under two-directional lateral loads in addition to the vertical load.Through three-dimensional numerical modeling based on Flac 3D software,the study ex... This research investigates the behavior of a 2×2 pile group under two-directional lateral loads in addition to the vertical load.Through three-dimensional numerical modeling based on Flac 3D software,the study examines the total bearing capacity and efficiency coefficient of the pile group,considering factors such as the angle of lateral load,relative pile spacing,and relative stiffness of the pile-soil system.The findings highlight the significance of these factors in understanding and predicting the response of pile groups to changing lateral load directions.The results reveal that increasing the angle of the lateral load from 0°to 45°enhances both the maximum total lateral load and the efficiency coefficient of the pile group.When the relative stiffness of the pile-soil system significantly increases,soil stiffening occurs and reducing the relative spacing of the piles from 7 to 3 times the diameter of the piles diminishes the influence of the pile group.Consequently,the response of the pile group to lateral loads becomes more linear,with only a slight alteration in the maximum total lateral load and the efficiency coefficient when the lateral load is angled from 0°to 45°.Conversely,increasing the relative distance between the piles,specifically from 3 to 7 times the diameter of the piles,amplifies the influence of the pile group.Both the maximum total lateral load and the efficiency coefficient of the pile group exhibit an observed increase.These provide insights for designing pile groups and optimizing their performance under lateral loading conditions. 展开更多
关键词 pile group two-way lateral load load capacity efficiency coefficient Flac 3d
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Energy Efficiency Optimization for D2D Communications Based on SCA and GP Method 被引量:3
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作者 Xiaozheng Gao Hangcheng Han +1 位作者 Kai Yang Jianping An 《China Communications》 SCIE CSCD 2017年第3期66-74,共9页
In this paper, we propose an energy-efficient power control scheme for device-to-device(D2D) communications underlaying cellular networks, where multiple D2D pairs reuse the same resource blocks allocated to one cellu... In this paper, we propose an energy-efficient power control scheme for device-to-device(D2D) communications underlaying cellular networks, where multiple D2D pairs reuse the same resource blocks allocated to one cellular user. Taking the maximum allowed transmit power and the minimum data rate requirement into consideration, we formulate the energy efficiency maximization problem as a non-concave fractional programming(FP) problem and then develop a two-loop iterative algorithm to solve it. In the outer loop, we adopt Dinkelbach method to equivalently transform the FP problem into a series of parametric subtractive-form problems, and in the inner loop we solve the parametric subtractive problems based on successive convex approximation and geometric programming method to obtain the solutions satisfying the KarushKuhn-Tucker conditions. Simulation results demonstrate the validity and efficiency of the proposed scheme, and illustrate the impact of different parameters on system performance. 展开更多
关键词 device-to-device(d2d communications power control energy efficiency(EE) successive convex approximation(SCA) geometric programming(GP)
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供应链金融对中小企业R&D投资效率的影响:基于融资约束视角 被引量:6
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作者 胡海青 原敏倩 薛萌 《科技进步与对策》 北大核心 2025年第1期102-112,共11页
创新是中小企业保持竞争力、适应市场变化和实现可持续发展的关键。基于2016-2022年创业板中小企业相关数据,运用三阶段DEA分析、面板Tobit模型回归、二元Logistic回归等方法,探究供应链金融对中小企业R&D投资效率的影响。结果表明... 创新是中小企业保持竞争力、适应市场变化和实现可持续发展的关键。基于2016-2022年创业板中小企业相关数据,运用三阶段DEA分析、面板Tobit模型回归、二元Logistic回归等方法,探究供应链金融对中小企业R&D投资效率的影响。结果表明,供应链金融能够显著提高中小企业R&D投资效率,融资约束在二者间发挥遮掩效应。进一步分析发现,上述效应对供应链集中度较高的企业更为显著。结论可为发挥供应链金融筹资优势,促进供应链生态系统资源互补、信息共享的协同创新网络形成,进而支持中小企业创新活动提供理论支持。 展开更多
关键词 供应链金融 r&d投资效率 三阶段dEA 面板Tobit模型 遮掩效应
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Energy efficiency optimization of relay-assisted D2D two-way communications with SWIPT
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作者 HE Jiai CHEN Yanjiao WANG Tong 《High Technology Letters》 EI CAS 2022年第3期252-258,共7页
Aiming at the energy consumption of long-distance device-to-device(D2D) devices for two-way communications in a cellular network,this paper proposes a strategy that combines two-way relay technology(TWRT) and simultan... Aiming at the energy consumption of long-distance device-to-device(D2D) devices for two-way communications in a cellular network,this paper proposes a strategy that combines two-way relay technology(TWRT) and simultaneous wireless information and power transfer(SWIPT) technology to achieve high energy efficiency(EE) communication.The scheme first establishes a fractional programming problem to maximize EE of D2D,and transforms it into a non-fractional optimization problem that can be solved easily.Then the problem is divided into three sub-problems:power control,power splitting ratios optimization,and relay selection.In order to maximize EE of the D2D pair,the Dinkelbach iterative algorithm is used to optimize the transmitted power of two D2D devices simultaneously;the one-dimensional search algorithm is proposed to optimize power splitting ratios;an improved optimal relay selection scheme based on EE is proposed to select relay.Finally,experiments are carried out on the Matlab simulation platform.The simulation results show that the proposed algorithm has faster convergence.Compared with the one-way relay transmission and fixed relay algorithms,the proposed scheme has higher EE. 展开更多
关键词 device-to-device(d2d) energy efficiency(EE) simultaneous wireless information and power transfer(SWIPT) two-way communications power control relay selection
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Effects of R134a Saturation Temperature on a Shell and Tube Condenser with the Nanofluid Flow in the Tube Using the Thermal Efficiency and Effectiveness Concepts
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作者 Élcio Nogueira 《World Journal of Nano Science and Engineering》 2021年第1期1-24,共24页
The work’s objective is to analyze the influence of the saturation temperature of the R134a refrigerant on the thermal performance of a shell and tube type condenser, with water and aluminum oxide (Al<sub>2<... The work’s objective is to analyze the influence of the saturation temperature of the R134a refrigerant on the thermal performance of a shell and tube type condenser, with water and aluminum oxide (Al<sub>2</sub>O<sub>3</sub>) nanoparticles flowing into the tube. For analysis, the heat exchanger is subdivided into three regions: subcooled liquid, saturated steam, and superheated steam. The shell and tube heat exchanger assumed as the basis for the study has 36 tubes, with rows of 4 tubes in line and three passes into the tube in each region. The parameters used to analyze the performance are efficiency and effectiveness, through variations of quantities such as saturation temperature, the nanofluid’s mass flow rate, fraction in the nanoparticles’ volume, and the number of passes in the tube in each region of the heat exchanger. The obtained results demonstrate that the efficiency is relatively high in all the analyzed situations. In each saturation temperature, the effectiveness can be increased by introducing fractions of nanoparticles in the water or increasing the number of passes in the tube. 展开更多
关键词 Shell and Tube Condenser r134A NANOFLUId Thermal efficiency Thermal Effectiveness
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Economic Benefit Estimating of Polydimensional Efficiency Measurement Model Implementation
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作者 Andrey Aleksandrovich Shishkin Olga Andreevna Tyugai 《Open Journal of Applied Sciences》 2015年第3期108-114,共7页
This paper is a revised and expanded version of a paper entitled “The static and dynamic criteria of building an investment asset portfolio” presented at International Conference on Applied Economics (ICOAE, 2014), ... This paper is a revised and expanded version of a paper entitled “The static and dynamic criteria of building an investment asset portfolio” presented at International Conference on Applied Economics (ICOAE, 2014), Chania, 3-5 July 2014 and published at Procedia Economics and Finance, Volume 14, Pages 575-584 (2014) [1]. At the previous research, it showed the significance to go beyond the scope of selecting one or another metric of static efficiency. And the attention was paid to the dynamic efficiency criteria. The ICOAE 2015 research gives brief results of that work, which is only one of applied areas of polydimensional efficiency measurement model (PEMM). Research work on PEMM conceptual and methodical elaboration has been started in the author’s dissertation study [2] and continued in the practical activity and materialized in Innovative LLC (limited liability company) creating project. The research is concentrating on the real economic benefit of 3D PEMM (thee criterial PEMM version) implementation. In the first part of ICOAE 2015 empirical study, the dynamic component of 3D PEMM on the industrial level was tested. Next, the company economic profit changes and dynamic-market 3D PEMM components correlation was estimated. Finally, the economic benefit of 3D PEMM functional operationalization in the framework of management systems development was calculated. 展开更多
关键词 Investment Portfolio Shareholder VALUE Economic VALUE Added dynamic Performance CrITErION CrITErION VALUE BASEd MANAGEMENT efficiency Evaluation MOdEL 3d MOdEL VALUE BASEd MANAGEMENT Corporate Governance Balanced Scorecard
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经济政策不确定性、风险感知与企业R&D投资阶段选择
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作者 成力为 吴薇 《管理工程学报》 北大核心 2025年第6期1-15,共15页
在经济衰退背景下,企业研发(R&D)投资阶段前移,加大基础研究与应用研究投入是高质量发展的必然选择。本文将外部风险感知到企业内部风险感知的传导过程纳入经济政策不确定性下的企业研发投资决策模型,从资源供给效应和机会成本效应... 在经济衰退背景下,企业研发(R&D)投资阶段前移,加大基础研究与应用研究投入是高质量发展的必然选择。本文将外部风险感知到企业内部风险感知的传导过程纳入经济政策不确定性下的企业研发投资决策模型,从资源供给效应和机会成本效应揭示影响企业研究阶段与开发阶段投资选择的机制。接着,利用2011—2020年中国上市制造业企业数据进行实证检验发现:(1)在机会成本效应主导下,经济政策不确定性对企业研究阶段投资存在显著激励作用;当资源供给效应占主导时,经济政策不确定性对开发阶段投资具有显著的抑制作用;(2)机制分析发现,经济政策不确定性上升会增强银行短期信贷偏好,进而抑制企业研究阶段投资。这进一步强化了企业内部风险感知,企业会通过“短债长用”等措施放大机会成本效应,从而有效缓解了短期信贷对研究阶段投资的负面影响。这种影响在高成熟度、低融资约束和低短期借款依赖度的企业中更为明显。此外,在资源供给效应主导下,经济政策不确定性可以通过降低股票流动性来抑制企业开发阶段投资。本文强调经济政策不确定性首先被金融机构和资本市场感知,接着通过外部融资约束传导至企业内部,进而强化企业的风险感知,使企业能够利用规避风险工具调节不同阶段的研发投资。 展开更多
关键词 经济政策不确定性 r&d投资阶段 风险感知 机会成本效应 资源供给效应
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基于因子分析的政府R&D投入绩效评价
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作者 赵志泉 林艳艳 李志敏 《科技和产业》 2025年第12期308-314,共7页
创新驱动为经济社会发展提供新动能,是引领未来经济转型的核心途径。政府R&D投入反映国家意志,有必要对其产出效率进行评价。利用2018—2022年31个省份(因数据缺失,未包含港澳台地区)的面板数据,从投入产出两个方面选取13个具体指... 创新驱动为经济社会发展提供新动能,是引领未来经济转型的核心途径。政府R&D投入反映国家意志,有必要对其产出效率进行评价。利用2018—2022年31个省份(因数据缺失,未包含港澳台地区)的面板数据,从投入产出两个方面选取13个具体指标构建政府R&D投入绩效评价指标体系,采用因子分析法对政府R&D投入绩效进行研究;结合模型的构建以及结果分析,提出通过推进R&D经费投入方式多元化、优化政府R&D经费投入执行结构、提高R&D人员投入来提高政府R&D投入绩效。 展开更多
关键词 政府r&d投入 因子分析 绩效评价
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社区嵌入式养老托育服务模型构建及内涵阐释——基于“D-R-S”联动视角的多案例研究
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作者 方建华 李金龙 刘思羽 《吉林师范大学学报(人文社会科学版)》 2025年第6期79-88,共10页
随着我国少子化、老龄化程度逐渐加深,社区嵌入式养老托育服务有利于解决“一老一小”的照护问题。研究基于“D-R-S”(需求—资源—制度)联动分析框架,对北京市朝阳区、温州市瓯海区、深圳市宝安区三个社区进行多案例分析,三个社区在实... 随着我国少子化、老龄化程度逐渐加深,社区嵌入式养老托育服务有利于解决“一老一小”的照护问题。研究基于“D-R-S”(需求—资源—制度)联动分析框架,对北京市朝阳区、温州市瓯海区、深圳市宝安区三个社区进行多案例分析,三个社区在实践过程中进行了“个性需求+共性需求+互补性需求”的多方审视,实现了“人力资源+物力资源+财力资源”的多方驱动,完成了“管理制度+监督制度+评估制度”的多方支持,构建了凸显拉动力、推动力和原动力的需求融合、资源融合、制度融合三方联动的社区嵌入式养老托育服务模型,以期为社会治理提供新的理论框架和实践路径。 展开更多
关键词 社区嵌入式养老托育服务 d-r-S”联动视角 多案例分析 “一老一小” 模型建构
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基于非洲猪瘟病毒D250R蛋白间接ELISA抗体检测方法的建立
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作者 朱文青 徐丽华 +6 位作者 刘佳畦 邬雨倩 金子安 吴旭琪 袁秀芳 周继勇 郑肖娟 《中国兽医科学》 北大核心 2025年第5期599-607,共9页
D250R是非洲猪瘟病毒(African swine fever virus,ASFV)感染早期表达的具有脱帽酶活性的非结构蛋白。本研究构建了重组原核表达质粒pET-32a-D250R,经IPTG诱导和镍亲和纯化成功获得原核细胞表达的重组蛋白His-D250R,该蛋白和真核细胞表... D250R是非洲猪瘟病毒(African swine fever virus,ASFV)感染早期表达的具有脱帽酶活性的非结构蛋白。本研究构建了重组原核表达质粒pET-32a-D250R,经IPTG诱导和镍亲和纯化成功获得原核细胞表达的重组蛋白His-D250R,该蛋白和真核细胞表达的重组蛋白Flag-D250R均能被ASFV标准阳性血清识别,证明D250R蛋白是ELISA抗体检测方法的潜在靶标。在此基础上,以纯化的重组蛋白为免疫原制备小鼠源多克隆抗体,该抗体ELISA效价大于1∶409600。Western-blot试验表明该抗体与Flag-D250R和His-D250R均具有良好的反应性,证明His-D250R蛋白具有良好的抗原性。进一步以His-D250R蛋白为包被抗原,通过对抗原包被、封闭、抗体孵育、底物反应等条件的优化,建立间接ELISA抗体检测方法。其阴阳性临界值为0.359,检测PRV、PRRSV、PCV2、CSFV等阳性血清结果均呈阴性,灵敏度达1∶3200,批内和批间重复性试验的变异系数均小于10%,与商品化试剂盒符合率达98.8%。上述结果表明,基于His-D250R蛋白建立的间接ELISA抗体检测方法特异性、敏感性、重复性良好,具备一定临床应用价值,可以为非洲猪瘟诊断方法开发提供重要支持。 展开更多
关键词 非洲猪瘟病毒 d250r蛋白 原核表达 多克隆抗体 间接ELISA
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选择赢家还是打造赢家?政府R&D补贴政策与企业技术创新作用机制研究 被引量:1
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作者 陈朝月 许治 卢涛 《管理评论》 北大核心 2025年第9期124-136,共13页
政府如何制定合理遴选补贴对象标准以实现企业创新增长,对补贴政策的制定和评价具有重要意义。本文在采用大规模创新调查数据集并考虑内生性问题基础上,从“选择赢家”和“打造赢家”两个方面探讨了政府补贴对企业创新的影响机制。结果... 政府如何制定合理遴选补贴对象标准以实现企业创新增长,对补贴政策的制定和评价具有重要意义。本文在采用大规模创新调查数据集并考虑内生性问题基础上,从“选择赢家”和“打造赢家”两个方面探讨了政府补贴对企业创新的影响机制。结果表明:政府补贴倾向于选择高组织学习能力的企业,经验学习、认知学习和组织间学习是其重要的遴选标准,其选择路径为高组织学习能力的企业偏向于外部技术获取模式,能够更为稳定快速地实现补贴目标。在控制选择偏差的基础上,政府补贴具有显著的“打造赢家”效应,其中普惠型补贴引致效应最高,自由裁量型补贴次之,选择型补贴最低。进一步对企业分组发现,在国有企业、大型企业和非初创企业中,经验学习并非政府补贴的遴选标准,并且政府补贴的“打造赢家”效应在上述企业中更为显著。 展开更多
关键词 政府补贴 选择赢家 打造赢家 创新绩效
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非洲猪瘟病毒D205R蛋白单克隆抗体的制备和抗原表位鉴定
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作者 林志钊 赵燕燕 +6 位作者 任豪杰 史赛燕 韩世充 何文瑞 万博 张雨杭 张改平 《河南农业科学》 北大核心 2025年第2期124-130,共7页
非洲猪瘟(ASF)是一种致命的传染病,迄今为止,还没有开发出有效的疫苗或药物用于预防或控制ASF。为提供诊断非洲猪瘟病毒(ASFV)的重要材料,利用大肠杆菌系统表达ASFV重组D205R蛋白,制备D205R蛋白的单克隆抗体(mAb),鉴定mAb识别的抗原表... 非洲猪瘟(ASF)是一种致命的传染病,迄今为止,还没有开发出有效的疫苗或药物用于预防或控制ASF。为提供诊断非洲猪瘟病毒(ASFV)的重要材料,利用大肠杆菌系统表达ASFV重组D205R蛋白,制备D205R蛋白的单克隆抗体(mAb),鉴定mAb识别的抗原表位。结果显示,成功构建pET32a-D205R表达质粒,并纯化大小约为44 ku的重组D205R蛋白。蛋白质免疫印迹(Western blot)检测结果表明,重组D205R蛋白与ASFV阳性血清发生特异性反应,有良好的免疫原性。利用杂交瘤细胞融合、筛选的方法,得到mAb 19A5。Western blot和间接免疫荧光试验(IFA)检测结果表明,mAb 19A5能特异性识别真核表达的重组D205R蛋白,并能检测到野生型D205R蛋白。用丙氨酸扫描法鉴定出167-SDPPVVWLGGRPGD-180是mAb 19A5的抗原表位,S167、W173、L174、G175、P178和D180是与mAb19A5结合的关键氨基酸。保守性和结构分析表明,抗原表位高度保守,且位于蛋白质表面,是线性表位。综上,成功制备mAb 19A5,并鉴定了mAb 19A5识别的抗原表位。 展开更多
关键词 非洲猪瘟病毒 d205r蛋白 单克隆抗体 抗原表位
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绿色金融、R&D投入与碳排放的内在关联性研究——基于省际面板数据的实证检验 被引量:2
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作者 刘伟 纪明 +1 位作者 韩进 王竞一 《工业技术经济》 北大核心 2025年第3期45-55,共11页
“碳达峰”和“碳中和”目标下,如何推动中国碳减排与经济绿色低碳转型,已经成为中国高质量发展的重要议题。本文基于2010~2022年我国30个省(区、市)的面板数据,探析了绿色金融和科技研发对碳排放的影响,实证证明了绿色金融与R&D投... “碳达峰”和“碳中和”目标下,如何推动中国碳减排与经济绿色低碳转型,已经成为中国高质量发展的重要议题。本文基于2010~2022年我国30个省(区、市)的面板数据,探析了绿色金融和科技研发对碳排放的影响,实证证明了绿色金融与R&D投入均对碳排放起到显著的抑制作用,而且R&D投入在绿色金融与碳排放之间的起到显著的负向调节作用,它既是绿色金融政策落地的关键驱动力,也是减少碳排放的重要技术手段。因此,我国应当加强绿色金融政策支持、发挥R&D投入和技术创新在实现碳减排中的关键驱动作用,同时推动绿色金融与科技研发协同发展。 展开更多
关键词 绿色金融 科技创新 r&d投入 碳排放 熵权法 单位根检验 区域异质性 科技研发
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