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Design and Exploration of Intelligent Software Testing Course
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作者 Depeng Gao Rui Wu +1 位作者 Shihan Xiao Shuxi Chen 《计算机教育》 2026年第3期47-53,共7页
With the rapid development of artificial intelligence,the intelligence level of software is increasingly improving.Intelligent software,which is widely applied in crucial fields such as autonomous driving,intelligent ... With the rapid development of artificial intelligence,the intelligence level of software is increasingly improving.Intelligent software,which is widely applied in crucial fields such as autonomous driving,intelligent customer service,and medical diagnosis,is constructed based on complex technologies like machine learning and deep learning.Its uncertain behavior and data dependence pose unprecedented challenges to software testing.However,existing software testing courses mainly focus on conventional contents and are unable to meet the requirements of intelligent software testing.Therefore,this work deeply analyzed the relevant technologies of intelligent software testing,including reliability evaluation indicator system,neuron coverage,and test case generation.It also systematically designed an intelligent software testing course,covering teaching objectives,teaching content,teaching methods,and a teaching case.Verified by the practical teaching in four classes,this course has achieved remarkable results,providing practical experience for the reform of software testing courses. 展开更多
关键词 Intelligent software testing Intelligent software software testing Course design
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OSSerCopilot:An LLM-driven Tutoring System for Fostering Open Source Competency in Software Engineering Education
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作者 Xin Tan Jingyi Tan +4 位作者 Weimiao Ren Keqing Fan Xiao Long Fang Liu Li Zhang 《计算机教育》 2026年第3期119-129,共11页
In the context of large language model(LLM)reshaping software engineering education,this paper presents OSSerCopilot,a LLM-based tutoring system designed to address the critical challenge faced by newcomers(especially... In the context of large language model(LLM)reshaping software engineering education,this paper presents OSSerCopilot,a LLM-based tutoring system designed to address the critical challenge faced by newcomers(especially student contributors)in open source software(OSS)communities.Leveraging natural language processing,code semantic understanding,and learner profiling,the system functions as an intelligent tutor to scaffold three core competency domains:contribution guideline interpretation,project architecture comprehension,and personalized task matching.By transforming traditional onboarding barriers-such as complex contribution documentation and opaque project structures-into interactive learning journeys,OSSerCopilot enables newcomers to complete their first OSS contribution more easily and confidently.This paper highlights how LLM technologies can redefine software engineering education by bridging the gap between theoretical knowledge and practical OSS participation,offering implications for curriculum design,competency assessment,and sustainable OSS ecosystem cultivation.A demonstration video of the system is available at https://figshare.com/articles/media/OSSerCopilot_Introduction_mp4/29510276. 展开更多
关键词 software engineering education Open source software education Intelligent tutoring systems Newcomer onboarding Large language models AI-driven educational tools OSS contribution
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Software and layout optimization of HIRFL-CSR external-target experiment
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作者 Jian-Wang Hong Chen-Lu Hu +29 位作者 Yu-Hong Yu Nu Xu Zhi-Yu Sun Hao Qiu Zhi-Gang Xiao Ming Shao Li-Min Duan Xiong-Hong He Zhi-Hui Xu Yi Wang Dong Han Zi-Xuan Chen Feng-Yi Zhao He-Run Yang Xiang-Lun Wei Rong-Jiang Hu Feng Liu Hua Pei Ya-Ping Wang Ye Tian Zhi Qin Dong-Dong Hu Guo-Dong Shen Li-Jun Mao Wei Wu Wei You Yu-Quan Chen Peng Yang De-Qing Fang Ya-Peng Zhang 《Nuclear Science and Techniques》 2026年第5期289-297,共9页
Heavy-ion collisions(HICs)is a unique experimental tool for investigating the properties of nuclear matter under extreme conditions in the laboratory.At HIRFL-CSR energies,HICs can create nuclear matter with 2-3 times... Heavy-ion collisions(HICs)is a unique experimental tool for investigating the properties of nuclear matter under extreme conditions in the laboratory.At HIRFL-CSR energies,HICs can create nuclear matter with 2-3 times the saturation density(ρ_(0)).The HIRFL-CSR external-target experiment(CEE)is a large-acceptance spectrometer designed to explore frontier topics in high-energy nuclear physics,such as the QCD phase structure and nuclear matter equation of states.In this letter,we introduce simulation and analysis software for the CEE experiment(CeeROOT).Based on the CEE conceptual design and CeeROOT software,the configurations of its subdetectors were optimized by considering foreseeable physical constraints.The final detector layout of the CEE spectrometer and its acceptances were validated through simulations of U+U collisions at 500 MeV/u and pp collisions at 2.8 GeV,which demonstrated that the CEE experiment will serve as a detector with wide acceptance and multi-particle identification capabilities for studying high-energy nuclear physics topics at HIRFL-CSR energies with pp,pA,and A A collisions. 展开更多
关键词 CEE experiment Simulation software OPTIMIZATION HIrFL-CSr
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Enhancing Code Quality with LLM in Software Static Analysis
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作者 Niu Zhi Dong Luming 《ZTE Communications》 2026年第1期65-71,共7页
In the modern era of ubiquitous and highly interconnected information technology,cybersecurity threats stemming from software code vulnerabilities have become increasingly severe,posing significant risks to the confid... In the modern era of ubiquitous and highly interconnected information technology,cybersecurity threats stemming from software code vulnerabilities have become increasingly severe,posing significant risks to the confidentiality,integrity,and availability of modern information systems.To enhance software code quality,enterprises often integrate static code analysis tools into Continuous Integration(CI) pipelines.However,the high rates of false positives and false negatives remain a challenge.The advent of large language models(LLMs),such as ChatGPT,presents a new opportunity to address these challenges.In this paper,we propose AI-SCDF,a framework that utilizes the custombuilt Nebula-Coder AI model for detecting and fixing code security issues in real time during the developer ' s personal build process.We construct a static code checking rule knowledge base through summarizing and classifying Common Weakness Enumeration(CWE) code security problems identified by security and quality assurance teams.The rule knowledge base is combined with CodeFuse-processed code contexts to serve as input for an AI code security detection microservice,which assists in identifying code quality and security issues.If any abnormalities are detected,they are addressed by an AI code security patching microservice,which alerts the developer and requests confirmation before committing the code into the repository.Experimental results show that our approach effectively improves code quality.We also develop a VS Code plugin for code alert detection and fix based on LLMs,which facilitates test shift-left and lowers the risk of software development. 展开更多
关键词 software static analysis LLM CWE knowledge base
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Research and Practice of a New Training Model for Software Engineering Courses Based on Generative AI and OBE Concepts
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作者 Shengshai Zhang Xiaodong Yu +1 位作者 Jianhui Jiang Lixiao Zhang 《计算机教育》 2026年第3期139-147,共9页
With the advent of the AI era,how can students effectively utilize generative AI large models to assist in course learning?At the same time,how can teachers utilize generative AI tools and the teaching concept of OBE ... With the advent of the AI era,how can students effectively utilize generative AI large models to assist in course learning?At the same time,how can teachers utilize generative AI tools and the teaching concept of OBE to stimulate students’innovative consciousness and teamwork ability,enabling students to identify some problems in a certain industry or field and creatively propose feasible solutions,and truly achieve the cultivation of new models in software engineering course teaching with the assistance of generative AI tools?This paper presents research and practice on a new model for cultivating software engineering courses that integrates generative AI and OBE,introduces the specific process of teaching reform and practice,and finally explains the achievements of teaching reform. 展开更多
关键词 Generative AI OBE software engineering Teaching reform
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Developing Innovation Capacity in Graduate Software Engineering Practice Through Newquality Productive Forces
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作者 Ting Cai Tianyuan Yin +2 位作者 Yuxin Wu Shan Lin Zhiwei Ye 《计算机教育》 2026年第3期220-229,共10页
The rapid development of new-quality productive forces(NQPF)has intensified the demand for high-level innovative talent.As a representative of NQPF,generative artificial intelligence(GenAI)offers powerful tools to res... The rapid development of new-quality productive forces(NQPF)has intensified the demand for high-level innovative talent.As a representative of NQPF,generative artificial intelligence(GenAI)offers powerful tools to reshape talent cultivation but also presents significant challenges,including skill hollowing,ethical risks,and a growing disconnect between education and industry needs.Currently,graduate-level software engineering education struggles with outdated curricula and insufficient alignment with practical demands.In this paper,we propose a dual-core collaborative framework driven by“GenAI technology”and“industry demand”.Under this framework,we design a four-dimensional capability development path to enhance graduate students’innovation in software engineering practice.This path focuses on①scientific research innovation,②engineering problem-solving,③cross-domain collaborative evolution,and④ethical risk governance.The proposed approach promotes a shift from traditional knowledge transfer to human-machine collaborative innovation,aligning talent cultivation with the demands of the NQPF. 展开更多
关键词 New-quality productive forces GenAI Graduate student software engineering Innovation ability
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Exploring Reform Strategies for Software Engineering Talent Development Models in the AI Era
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作者 Linying Jiang Guibing Guo +1 位作者 Jianzhe Zhao Xiaochun Yang 《计算机教育》 2026年第3期95-100,共6页
The rapid development of artificial intelligence(AI)has placed significant pressure on universities to rethink how they train software engineering students.Tools like GitHub Copilot can now generate basic code in seco... The rapid development of artificial intelligence(AI)has placed significant pressure on universities to rethink how they train software engineering students.Tools like GitHub Copilot can now generate basic code in seconds.This raises important questions:What is the value of traditional programming education?What role should instructors play when AI becomes a powerful teaching assistant?How should the goals of software engineering programs change as companies increasingly use AI to handle coding tasks?This paper explores the key challenges AI brings to software engineering education and proposes practical strategies for updating talent development models to meet these changes. 展开更多
关键词 Artificial intelligence software engineering education Talent development reform strategies
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GranuSAS:Software of rapid particle size distribution analysis from small angle scattering data
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作者 Qiaoyu Guo Fei Xie +3 位作者 Xuefei Feng Zhe Sun Changda Wang Xuechen Jiao 《Chinese Physics B》 2026年第2期216-225,共10页
Small angle x-ray scattering(SAXS)is an advanced technique for characterizing the particle size distribution(PSD)of nanoparticles.However,the ill-posed nature of inverse problems in SAXS data analysis often reduces th... Small angle x-ray scattering(SAXS)is an advanced technique for characterizing the particle size distribution(PSD)of nanoparticles.However,the ill-posed nature of inverse problems in SAXS data analysis often reduces the accuracy of conventional methods.This article proposes a user-friendly software for PSD analysis,GranuSAS,which employs an algorithm that integrates truncated singular value decomposition(TSVD)with the Chahine method.This approach employs TSVD for data preprocessing,generating a set of initial solutions with noise suppression.A high-quality initial solution is subsequently selected via the L-curve method.This selected candidate solution is then iteratively refined by the Chahine algorithm,enforcing constraints such as non-negativity and improving physical interpretability.Most importantly,GranuSAS employs a parallel architecture that simultaneously yields inversion results from multiple shape models and,by evaluating the accuracy of each model's reconstructed scattering curve,offers a suggestion for model selection in material systems.To systematically validate the accuracy and efficiency of the software,verification was performed using both simulated and experimental datasets.The results demonstrate that the proposed software delivers both satisfactory accuracy and reliable computational efficiency.It provides an easy-to-use and reliable tool for researchers in materials science,helping them fully exploit the potential of SAXS in nanoparticle characterization. 展开更多
关键词 small angle x-ray scattering data analysis software particle size distribution inverse problem
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Exploration and Practice of School-Enterprise Cooperation Model of Software Engineering Majors from Multi-Perspectives
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作者 Linpeng Zhong Yong Liao 《计算机教育》 2026年第3期38-46,共9页
Promoting the integration of industry and education and deepening school-enterprise cooperation in talent cultivation and collaborative innovation are long-term goals of higher education.This paper systematically anal... Promoting the integration of industry and education and deepening school-enterprise cooperation in talent cultivation and collaborative innovation are long-term goals of higher education.This paper systematically analyzes the multiple perspectives,practical challenges,and implementation paths of in-depth school-enterprise cooperation.Based on the typical case of school-enterprise cooperation at the School of Information and Software Engineering,University of Electronic Science and Technology of China(UESTC),this paper explores the innovative practices of in-depth school-enterprise cooperation in talent cultivation,scientific research,and faculty construction.It also explores a multi-party collaborative mechanism from the perspectives of universities,enterprises,students,and the government.By policy guidance,resource integration,and benefit sharing,this mechanism achieves in-depth integration of industry and education,providing references and examples for further development of school-enterprise cooperation in the new era. 展开更多
关键词 software engineering School-enterprise cooperation Integration of industry and education Collaborative talent cultivation Multi-perspective analysis
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A Hybrid Approach to Software Testing Efficiency:Stacked Ensembles and Deep Q-Learning for Test Case Prioritization and Ranking
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作者 Anis Zarrad Thomas Armstrong Jaber Jemai 《Computers, Materials & Continua》 2026年第3期1726-1746,共21页
Test case prioritization and ranking play a crucial role in software testing by improving fault detection efficiency and ensuring software reliability.While prioritization selects the most relevant test cases for opti... Test case prioritization and ranking play a crucial role in software testing by improving fault detection efficiency and ensuring software reliability.While prioritization selects the most relevant test cases for optimal coverage,ranking further refines their execution order to detect critical faults earlier.This study investigates machine learning techniques to enhance both prioritization and ranking,contributing to more effective and efficient testing processes.We first employ advanced feature engineering alongside ensemble models,including Gradient Boosted,Support Vector Machines,Random Forests,and Naive Bayes classifiers to optimize test case prioritization,achieving an accuracy score of 0.98847 and significantly improving the Average Percentage of Fault Detection(APFD).Subsequently,we introduce a deep Q-learning framework combined with a Genetic Algorithm(GA)to refine test case ranking within priority levels.This approach achieves a rank accuracy of 0.9172,demonstrating robust performance despite the increasing computational demands of specialized variation operators.Our findings highlight the effectiveness of stacked ensemble learning and reinforcement learning in optimizing test case prioritization and ranking.This integrated approach improves testing efficiency,reduces late-stage defects,and improves overall software stability.The study provides valuable information for AI-driven testing frameworks,paving the way for more intelligent and adaptive software quality assurance methodologies. 展开更多
关键词 software testing test case prioritization test case ranking machine learning reinforcement learning deep Q-learning
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Exploration and Practice in Building a Diversified Faculty Team for Specialized Software Talent Cultivation
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作者 Fangshi Wang Weiwei Xing +1 位作者 Wei Lu Shunli Zhang 《计算机教育》 2026年第3期67-73,共7页
Faculty development serves as a critical foundation for ensuring the quality of higher education.To meet the needs of cultivating specialized software talents and promoting teaching reform,it is particularly crucial t... Faculty development serves as a critical foundation for ensuring the quality of higher education.To meet the needs of cultivating specialized software talents and promoting teaching reform,it is particularly crucial to build a faculty team with knowledge in industry application fields and experience in domestic software development.This paper first analyzes the new requirements for the faculty imposed by the cultivation of specialized software talents and the existing problems in the current faculty.Then,in response to these issues,it introduces the reforms and explorations carried out by the School of Software Engineering at Beijing Jiaotong University in the construction of the faculty for cultivating specialized software talents.The aim is to build a high-caliber and diversified faculty that boasts strong political qualities,interdisciplinary integration,complementary advantages between full-time and part-time faculty,and in-depth integration of industry and education. 展开更多
关键词 Specialized software talents Diversified faculty team Interdisciplinary integration Integration of industry and education
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Research and Implementation of the Academic Development Monitoring System for High-quality Software Engineering Talents
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作者 Kun Niu Kaiyang Zhang +5 位作者 Tan Yang Hui Gao Hongfeng Gu Ting Diao Jing Li Honglin Fu 《计算机教育》 2026年第3期199-209,共11页
Traditional grade-centered evaluation models are inadequate for high-quality software engineering talents in the digital and AI era.This study develops an academic development monitoring system to address shortcomings... Traditional grade-centered evaluation models are inadequate for high-quality software engineering talents in the digital and AI era.This study develops an academic development monitoring system to address shortcomings in dynamics,interdisciplinary integration,and industry adaptability.It builds a multi-dimensional dynamic model covering seven core dimensions with quantitative scoring,non-linear weighting,and DivClust grouping.An intelligent platform with real-time monitoring,early warning,and personalized recommendations integrates AI like multi-modal fusion and large-model diagnosis.The“monitoring-warning-improvement”loop helps optimize training programs,support personalized planning,and bridge talent-industry gaps,enabling digital transformation in software engineering education evaluation. 展开更多
关键词 software engineering talents Academic development monitoring Multi-dimensional dynamic evaluation Intelligent monitoring platform AI-driven evaluation Industry adaptability
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R290替代R134a新能源汽车压缩机仿真分析和实验研究
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作者 陈建红 陶乐仁 +3 位作者 黄理浩 王笑菲 李兴江 陈浩南 《制冷学报》 北大核心 2026年第2期43-50,共8页
由于新能源汽车的驱动方式与传统汽车不同,新能源汽车的电力来源方式可以多样化。由于制冷剂R290的全球变暖潜值(GWP)和臭氧损耗潜值(ODP)比R134a低,R290已成为新能源汽车空调发展的重要选择之一。通过搭建一套新能源汽车空调压缩机性... 由于新能源汽车的驱动方式与传统汽车不同,新能源汽车的电力来源方式可以多样化。由于制冷剂R290的全球变暖潜值(GWP)和臭氧损耗潜值(ODP)比R134a低,R290已成为新能源汽车空调发展的重要选择之一。通过搭建一套新能源汽车空调压缩机性能测试系统,针对不同的蒸发温度、冷凝温度、压缩机转速等,研究了不同工况下2种制冷剂R134a和R290的压缩机性能,并分析了2种制冷剂的仿真预测值和实验值的变化。结果表明:冷凝温度对R290和R134a压缩机的功率影响较大,冷凝温度上升1℃,压缩机功率约增加3%;蒸发温度对R290和R134a压缩机的功率影响较小,蒸发温度上升1℃,压缩机功率降低约0.3%。仿真模型对R134a及R290的压缩机功率预测误差分别为5%和10%。在相同的温差条件下,R290比R134a的压缩机性能有显著提高,等熵效率高10%~15%,容积效率高6%~9%。在相同的压比工况下,R290与R134a的压缩机性能相近。在变速压缩机的测试过程中,R290和R134a的压缩机性能随着转速的变化趋势基本一致。但半经验的仿真模型对变速压缩机的适用性还需要进一步优化,特别是在高转速时还需要考虑其他因素的影响。 展开更多
关键词 r290 压缩机 等熵效率 容积效率 仿真模型
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基于DUSt3R立体深度学习的散装粮堆体积测量方法研究
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作者 陈卫东 何为 +2 位作者 张继勇 张庆辉 符方铭 《河南工业大学学报(自然科学版)》 北大核心 2026年第1期105-113,共9页
针对传统粮堆体积测量方法中设备成本高、依赖相机标定、复杂形态适配性差等问题,提出一种基于密集无约束体三维重建(dense and unconstrained stereo 3D reconstruction,DUSt3R)点云的散装粮堆体积智能估算方法。该方法利用DUSt3R的注... 针对传统粮堆体积测量方法中设备成本高、依赖相机标定、复杂形态适配性差等问题,提出一种基于密集无约束体三维重建(dense and unconstrained stereo 3D reconstruction,DUSt3R)点云的散装粮堆体积智能估算方法。该方法利用DUSt3R的注意力机制与稠密匹配技术,实现端到端生成三维点云。构建基于粮堆特性的点云优化模块,结合统计滤波与RANSAC平面检测技术,提升点云噪声去除能力,并通过DBSCAN聚类实现粮堆与地面的精准分割。结果表明:该方法有效克服了对相机标定的依赖,显著提升了点云噪声处理与分割精度;通过动态网格投影与Alpha Shape曲面重建技术自适应拟合复杂粮堆形态,在保证测量准确性的同时大幅降低硬件成本,具备良好的工程适用性;在6种典型粮堆形态上开展试验验证,平均测量误差约为5%,仅需普通摄像头即可完成数据采集。该体积测量方法可与平粮机器人作业设备高效集成,为散装粮堆体积测量与自动化作业引导提供了低成本、高精度的技术解决方案。 展开更多
关键词 平粮机器人 散装粮堆 DUSt3r 三维重建 体积计算
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基于R语言分析针灸治疗孤独症谱系障碍言语障碍的选穴规律
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作者 王兰 王兴 宋虎杰 《广州中医药大学学报》 2026年第2期425-433,共9页
【目的】基于R语言对针灸治疗孤独症谱系障碍(ASD)言语障碍文献的针灸处方进行数据挖掘,分析其用穴规律与特点。【方法】计算机检索中国知网期刊全文数据库(CNKI)、万方学术期刊全文数据库(Wanfang)、维普中文科技期刊数据库(VIP)、美... 【目的】基于R语言对针灸治疗孤独症谱系障碍(ASD)言语障碍文献的针灸处方进行数据挖掘,分析其用穴规律与特点。【方法】计算机检索中国知网期刊全文数据库(CNKI)、万方学术期刊全文数据库(Wanfang)、维普中文科技期刊数据库(VIP)、美国生物医学信息检索系统(PubMed)数据库有关针灸治疗孤独症谱系障碍(ASD)言语障碍文献的针灸处方。检索时间为各数据库自建库至2024年12月31日。运用Excel 2019和R语言对针灸处方进行频次分析、腧穴归经分析、关联规则分析、集合可视化分析以及聚类分析。【结果】共纳入73篇文献,提取有效处方129条,涉及112个腧穴及穴区,使用频次前5位的腧穴分别是百会、四神聪、神庭、言语三区、本神,使用频次最高的经脉分别是督脉、靳三针、焦氏头针。关联规则显示,常用穴位配伍组合共32组;集合可视化分析得到高频交集腧穴20组;聚类分析得到核心处方6组。【结论】针灸治疗ASD言语障碍以醒脑益智、疏利舌窍为原则;选穴多位于头部,以督脉穴、靳三针穴为主,加强通督调神之效;核心处方组为“言语三区、言语二区、言语一区、本神、神庭、四神聪”。 展开更多
关键词 针灸 孤独症谱系障碍 言语障碍 醒脑益智 疏利舌窍 通督调神 选穴规律 r语言
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3R出版物质量评价体系构建研究
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作者 万安伦 李梦竹 《出版发行研究》 北大核心 2026年第1期37-44,共8页
随着3R技术(VR、AR与MR技术)在出版领域的广泛应用,其质量评价标准缺失问题日益凸显。文章以“首届虚拟现实新闻出版创新应用案例”征集活动97个入选案例为支撑,在系统梳理现有出版物质量评价体系的基础上,依托德尔菲法征询专家意见,参... 随着3R技术(VR、AR与MR技术)在出版领域的广泛应用,其质量评价标准缺失问题日益凸显。文章以“首届虚拟现实新闻出版创新应用案例”征集活动97个入选案例为支撑,在系统梳理现有出版物质量评价体系的基础上,依托德尔菲法征询专家意见,参考“首届虚拟现实新闻出版创新应用案例”评审反馈,构建3R出版物质量评价体系,并利用主成分分析法(PCA)对各级指标赋权。通过探讨编辑、评审与用户场景的实际应用路径,为质量评价体系的实践落地提供参考,并进一步推动数字出版质量管理标准化与规范化发展。 展开更多
关键词 数字出版 出版物质量 质量评价体系 3r 出版
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miR-21靶向PIK3R1调控NLRP3介导急性胰腺炎腺泡细胞损伤及炎症反应
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作者 郑坚江 李智德 熊炬 《现代消化及介入诊疗》 2026年第1期9-15,共7页
目的探讨miR‐21是否通过靶向PIK3R1调控NLRP3表达,进而介导急性胰腺炎(Acute Pancreatitis,AP)腺泡细胞损伤、凋亡及炎症反应。方法以雨蛙素诱导AR42J细胞构建AP模型,通过CCK8、LDH检测及ELISA筛选最佳雨蛙素诱导浓度;将细胞分为Contro... 目的探讨miR‐21是否通过靶向PIK3R1调控NLRP3表达,进而介导急性胰腺炎(Acute Pancreatitis,AP)腺泡细胞损伤、凋亡及炎症反应。方法以雨蛙素诱导AR42J细胞构建AP模型,通过CCK8、LDH检测及ELISA筛选最佳雨蛙素诱导浓度;将细胞分为Control组、AP组、AP+NC mimics组、AP+miR‐21 mimics组、AP+NC inhibitor组、AP+miR‐21 inhibitor组,转染调控miR‐21表达后,采用CCK8检测细胞活力,流式细胞术检测凋亡率,LDH及ELISA检测细胞损伤和炎症因子水平,qPCR和Western blot检测miR‐21、PIK3R1、NLRP3的表达;双荧光素酶实验验证miR‐21与PIK3R1的靶向关系。结果雨蛙素100 nM为最佳诱导浓度。与Control组相比,AP组miR‐21和NLRP3表达显著升高,PIK3R1表达显著降低,细胞活力下降,凋亡率及LDH活性升高,IL‐1β、IL‐6、IL‐17、IL‐18水平升高(P均<0.05);与AP组相比,miR‐21 mimics组上述病理表型加剧,PIK3R1表达进一步降低,NLRP3表达进一步升高(P<0.05),而miR‐21 inhibitor组则呈相反趋势(P均<0.05);双荧光素酶实验证实miR‐21直接结合PIK3R1的3'UTR并抑制其表达。结论miR‐21可直接结合PIK3R1的3'UTR抑制其表达,解除对PI3K/Akt通路的抑制并激活该通路,进而上调NLRP3表达,加重急性胰腺炎腺泡细胞损伤、凋亡及炎症反应,该调控轴可能成为AP靶向治疗的潜在靶点。 展开更多
关键词 mir‐21 急性胰腺炎 PIK3r1 NLrP3 腺泡细胞
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4R危机管理理论在急诊介入手术中的应用
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作者 吴燕燕 陈红 +3 位作者 葛文程 凌燕 刘国涛 王冬梅 《护理实践与研究》 2026年第2期208-215,共8页
目的探究基于4R危机管理理论的干预方案在急诊介入手术室中的应用效果,以期控制急诊介入诊疗风险事件的发生,优化急诊介入手术临床工作流程,提高急诊介入手术患者的手术安全性和成功率。方法选取2021年1月—2023年12月医院急诊介入手术... 目的探究基于4R危机管理理论的干预方案在急诊介入手术室中的应用效果,以期控制急诊介入诊疗风险事件的发生,优化急诊介入手术临床工作流程,提高急诊介入手术患者的手术安全性和成功率。方法选取2021年1月—2023年12月医院急诊介入手术患者280例作为研究对象,其中2021年1月—2022年6月收治的140例患者作为对照组,实施常规护理;2022年7月—2023年12月收治的140例患者作为观察组,实施基于4R危机管理理论的急诊介入手术患者风险管理方案。另选取50名医师分为观察组和对照组,各25名。两个时间段各选择25名护士作为研究对象,统计护士风险防范理论知识水平、介入专科急救仪器设备操作技能,比较两组患者急诊介入手术风险事件发生率,手术医师对急诊介入手术护理配合的满意度。结果观察组护士介入手术室核心制度、相关法律法规知识评分均高于对照组,差异有统计学意义(P<0.05)。观察组护士除颤器、呼吸机、心电图、气管插管设备操作评分均高于对照组,差异有统计学意义(P<0.05)。观察组患者介入手术风险事件发生率低于对照组,差异有统计学意义(P<0.05)。观察组医师对急诊介入手术护理配合的满意度高于对照组,差异有统计学意义(P<0.05)。结论4R危机管理理论在急诊介入手术室中的应用,有助于进一步优化护理流程、提升医护团队的协同能力,提高急诊介入手术的安全性、减少风险,为患者提供更加优质的医疗服务。 展开更多
关键词 4r危机管理理论 急诊介入手术 护理风险 风险防范 操作技能 护理配合满意度
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基于改进Faster R-CNN的输变电工程塔基隐性病害GPR图像识别研究
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作者 程江洲 杨静怡 +1 位作者 鲍刚 罗应权 《地球物理学进展》 北大核心 2026年第1期442-452,共11页
针对输变电工程塔基因施工过程中操作不当及相关环境因素导致的混凝土隐性病害识别难题,本文提出了一种基于改进的Faster R-CNN网络GPR图像识别方法.首先,以ResNet-50为主干网络融合通道注意力机制,并通过层间位置对比实验优化了SE模块... 针对输变电工程塔基因施工过程中操作不当及相关环境因素导致的混凝土隐性病害识别难题,本文提出了一种基于改进的Faster R-CNN网络GPR图像识别方法.首先,以ResNet-50为主干网络融合通道注意力机制,并通过层间位置对比实验优化了SE模块的嵌入层级与位置,在强化关键特征提取的同时有效降低了计算冗余.其次,引入soft-NMS算法优化紧密相邻目标的边框预测精度,提高紧密相连目标的检测能力.最后,采用生成对抗网络扩增gprMax仿真生成的刚性直柱式基础GPR图像数据集,并对样本进行识别标注.实验结果表明,优化模型平均精度均值达到84.49%,F-Score为77.58%.相较于传统的FasterRCNN目标检测模型,改进模型识别精度提高了6.37%. 展开更多
关键词 探地雷达 隐性病害检测 Faster r-CNN 生成对抗网络
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基于改进Faster R-CNN-FPN的田间劳作行为目标检测算法
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作者 周艳青 邹铭鑫 +2 位作者 姜新华 白洁 马学磊 《内蒙古农业大学学报(自然科学版)》 北大核心 2026年第1期77-86,共10页
劳作行为检测时存在着检测精度不高和漏检等问题,利用Faster R-CNN和FPN提出一种改进的劳作行为检测模型。首先,在Faster R-CNN框架基础上,引入特征金字塔网络FPN,用于提高较小目标的检测能力。然后,为提高模型对不同尺度目标的泛化能力... 劳作行为检测时存在着检测精度不高和漏检等问题,利用Faster R-CNN和FPN提出一种改进的劳作行为检测模型。首先,在Faster R-CNN框架基础上,引入特征金字塔网络FPN,用于提高较小目标的检测能力。然后,为提高模型对不同尺度目标的泛化能力,加入多尺度MS训练;并利用内容感知特征重组CARAFE上采样算子替换FPN中的双线性插值上采样方式,实现大范围内像素的关联。最后,在自建的数据集FWBD上对改进的Faster R-CNN-FPN检测模型进行训练和测试。结果表明:(1)与YOLOv3模型相比,改进的劳作行为识别算法mAP为69.40%;(2)与原始模型Faster、Faster-CARAFER、Faster-MS相比,改进的算法模型mAP值最高,达到了71.05%,说明改进的算法模型能有效地实现田间劳作行为的检测,对农业生产实践具有实际应用价值。 展开更多
关键词 田间劳作 行为检测 Faster r-CNN 特征金字塔网络 内容感知特征重组
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