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Effects of Warming on Coastal Viral Decay and Production Rate
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作者 GAO Siru WANG Hongsong +1 位作者 LV Jiayi ZHAN Yuanchao 《Journal of Ocean University of China》 2026年第1期228-236,共9页
Viral infections play a crucial role in marine biogeochemical cycles,by regulating bacterial mortality and mediating nutrient and carbon fluxes.However,despite of their ecological significance,existing climate change ... Viral infections play a crucial role in marine biogeochemical cycles,by regulating bacterial mortality and mediating nutrient and carbon fluxes.However,despite of their ecological significance,existing climate change models generally fail to incorporate virus-mediated ecological processes due to the current limited understanding of marine viral dynamics under global warming.While numerous studies have explored the effect of warming for viral decay and production,how temperature regulates the total abundance of marine viruses remains unclear.In this study,we conducted year-round measurements of viral production and decay rates in Qingdao's coastal waters,with additional experimental warming treatments.The result showed that under in-situ temperature,the viral decay and production rate displayed distinct seasonal variations.With the exception of summer,elevated temperature stimulated both viral decay rate and production rate,and further improved the net viral production rate.While in summer,the net viral production rate turned negative,implying divergent threshold viral decay and viral production rate on warming.Our study deepens the understanding of the effect of global warming on marine viruses and provides scientific data for climate change models. 展开更多
关键词 viral decay viral production WARMING net viral production
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Process analysis of nuclear hydrogen production via intermediate temperature SOEC electrolysis
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作者 Qing Shao Yue Lu +7 位作者 Dun Jin Ling-Hong Luo Xiu-Lin Wang Hui-Chao Yao Ruo-Yun Dai Cheng-Zhi Guan Guo-Ping Xiao Jian-Qiang Wang 《Nuclear Science and Techniques》 2026年第2期122-133,共12页
When the operating temperature of a solid oxide electrolysis cell(SOEC)is lower than the outlet temperature of a nuclear reactor,the reactor can be directly coupled with the SOEC as a high-temperature heat source.Howe... When the operating temperature of a solid oxide electrolysis cell(SOEC)is lower than the outlet temperature of a nuclear reactor,the reactor can be directly coupled with the SOEC as a high-temperature heat source.However,the key to the efficiency and return on investment of this hybrid energy system lies in the expected lifetime of the SOEC.This study assessed Ni-YSZ|YSZ|GDC|LSC fuel electrode support cells’long-term stability during electrolysis at 650℃with a current density of−0.5Acm^(−2)over 1818 h.The average voltage degradation rate of 2.63%kh^(−1)unfolded in two phases:an initial rapid decay(90 to 1120 h at 3.58%kh^(−1))and a stable decay(1120 to 1818 h at 2.14%kh^(−1)),emphasizing SOECs’probability coupling with nuclear reactors at 650℃.Post-1818-hour electrolysis revealed nickel particle formation associated with Ni(OH)_(x)diffusion and re-deposition,alongside a strontium-containing layer causing interface cracking.Despite minimal strontium segregation in the EDS,XPS data indicated surface segregation of Sr.This study provides crucial insights into prolonged SOEC operation,highlighting both its potential and challenges. 展开更多
关键词 Nuclear hydrogen production SOEC STABILITY Intermediate temperature
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Production of ^(287,288)Mc isotopes in the ^(48)Ca+^(243)Am reaction at China Accelerator Facility for Superheavy Elements
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作者 X.Y.Huang Z.Y.Zhang +38 位作者 J.G.Wang L.Ma C.L.Yang M.H.Huang X.L.Wu Z.G.Gan H.B.Yang M.M.Zhang Y.L.Tian Y.S.Wang J.Y.Wang Y.H.Qiang G.Xie S.Y.Xu Z.Zhao Z.C.Li L.C.Sun L.Zhu X.Zhang H.Zhou F.Guan Z.H.Li W.X.Huang Z.Qin Y.Wang X.J.Yin Y.F.Cui Z.W.Lu Y.He L.T.Sun Z.Z.Ren S.G.Zhou V.K.Utyonkov A.A.Voinov Yu.S.Tsyganov A.N.Polyakov D.I.Solovyev N.D.Kovrizhnykh M.V.Shumeiko 《Chinese Physics Letters》 2026年第1期9-16,共8页
We report the results of the experiment on synthesizing ^(287,288)Mc isotopes (Z=115) using the fusionevaporation reaction ^(243)Am(^(48)Ca,4n,3n)^(287,288)Mc at the Spectrometer for Heavy Atoms and Nuclear Structure-... We report the results of the experiment on synthesizing ^(287,288)Mc isotopes (Z=115) using the fusionevaporation reaction ^(243)Am(^(48)Ca,4n,3n)^(287,288)Mc at the Spectrometer for Heavy Atoms and Nuclear Structure-2(SHANS2),a gas-filled recoil separator located at the China Accelerator Facility for Superheavy Elements(CAFE2).In total,20 decay chains are attributed to ^(288)Mc and 1 decay chain is assigned to ^(287)Mc.The measured oa-decay properties of ^(287,288)Mc as well as its descendants are consistent with the known data.No additional decay chains originating from the 2n or 5n reaction channels were detected.The excitation function of the ^(243)Am(^(48)Ca,3n)^(288)Mc reaction was measured at the cross-section level of picobarn,which indicates the promising capability for the study of heavy and superheavy nuclei at the facility. 展开更多
关键词 spectrometer heavy atoms fusionevaporation reaction China Accelerator Facility Superheavy Elements production decay chains ISOTOPES ca am reaction mc
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Harnessing CRISPR-Cas9 for Lactobacillus improvement in silage production:current knowledge and future perspectives
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作者 Jing Ma Jiao Zhang Xusheng Guo 《Journal of Animal Science and Biotechnology》 2026年第1期127-146,共20页
High-quality silage is the cornerstone to sustainable livestock development and animal food production.As the core fermentation bacteria of silage,Lactobacillus directly regulates silage fermentation by producing lact... High-quality silage is the cornerstone to sustainable livestock development and animal food production.As the core fermentation bacteria of silage,Lactobacillus directly regulates silage fermentation by producing lactic acid,enzymes,and other bioactive molecules.However,traditional screening methods for functional strains are labor-intensive and time-consuming.Recent advances in synthetic biology,particularly the development of CRISPR-Cas genome editing technology,offer a revolutionary approach to designing Lactobacillus strains with customized traits.This review systematically reviewed the importance of silage in sustainable agricultural development and the limitations of current silage preparation and promotion.It also discussed the application of strain engineering approaches in optimizing the phenotypic performance of Lactobacillus for better silage.Building on this,we reviewed the research progress of CRISPR-Cas9 gene editing in Lactobacillus and discussed how to leverage its high efficiency and precision to optimize the strain's traits for improved silage quality and functionality.CRISPR-Cas9 toolkits are expected to achieve directed evolution of strain performance,ultimately yielding next-generation silage microbial inoculants with multiple functions,adaptability to multiple substrates,and eco-friendly characteristics.The use of such innovative biotechnologies would facilitate resource-efficient utilization,promote animal performance and health for sustainable development in livestock production. 展开更多
关键词 Gene editing Lactobacillus engineering SILAGE Sustainable livestock production
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Genesis Mechanism of Heat Source in Mianhuakeng Uranium Deposit,South China:Insights from Radiogenic Heat Production of Granite Bodies
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作者 WANG Siqi ZHANG Baojian +2 位作者 LÜGuosen LIU Feng ZHU Xi 《Acta Geologica Sinica(English Edition)》 2026年第1期286-296,共11页
The Mianhuakeng uranium deposit,characterized by uranium-rich granite,serves as a key site for research into crustal radioactive heating.Based on 45 rock samples,this study reviews that the host granite in the Mianhua... The Mianhuakeng uranium deposit,characterized by uranium-rich granite,serves as a key site for research into crustal radioactive heating.Based on 45 rock samples,this study reviews that the host granite in the Mianhuakeng uranium deposit has a high radioactive heat production rate(avg.5.50μW/m³)and a low Th/U ratio(avg.2.62).Uranium-rich granite and its alteration zone within the upper crust(0-5 km depth)contribute about 45%of the total radioactive heat production,wich is crucial for controlling geothermal resource distribution.For uranium-thermal at tectonic plate margins,a symbiotic geological model was proposed:Firstly,subduction of the Pacific Plate caused upwelling of the asthenosphere,generating a high heat-flow background.Secondly,heat transfer is enhanced by major faults such as the Youdong and Mianhuakeng faults.Subsequently,uranium was mobilized,transported,and enriched within the granite through deep siliceous hydrothermal activity and associated alteration.Ultimately,the uranium enrichment in granite leads to increased radioactive heat production,resulting in local thermal anomalies.This model provides a theoretical support for exploring and developing uranium-thermal symbiotic resources in South China. 展开更多
关键词 uranium-rich granite radiogenic heat production heat source genesis mechanism Mianhuakeng uranium deposit
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Rational Design of Photoanodes in Portable Devices to Enhance H_(2)O_(2) Production for Microenvironment Control
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作者 Haisu Wu Hanliang Fan +4 位作者 Hong Chen Dongxue Jiao Yuanxing Fang Xiaochun Zheng Maokai Xu 《Carbon Energy》 2026年第1期48-59,共12页
Hydrogen peroxide(H_(2)O_(2))is a versatile oxidant with significant applications,particularly in regulating the microenvironment for healthcare purposes.Herein,a rational design of the photoanode is implemented to en... Hydrogen peroxide(H_(2)O_(2))is a versatile oxidant with significant applications,particularly in regulating the microenvironment for healthcare purposes.Herein,a rational design of the photoanode is implemented to enhance H_(2)O_(2) production by oxidizing H_(2)O in a portable photoelectrocatalysis(PEC)device.The obtained solution from this system is demonstrated for effective bactericidal activity against Staphylococcus aureus and Escherichia coli,while maintaining low toxicity toward hippocampal neuronal cells.The photoanode is achieved by Mo-doped BiVO4 films,which are subsequently loaded with cobalt-porphyrin(Co-py)molecules as a co-catalyst.As a result,the optimal performance for H_(2)O_(2) production rate was achieved at 8.4μmol h^(−1) cm^(−2),which is 1.8 times that of the pristine BiVO4 photoanode.Density functional theory(DFT)simulations reveal that the improved performance results from a 1.1 eV reduction in the energy of the rate-determining step of·OH adsorption by the optimal photoanode.This study demonstrates a PEC approach for promoting H_(2)O_(2) production by converting H_(2)O for antibacterial purposes,offering potential applications in conventionally controlling microenvironments for healthcare applications. 展开更多
关键词 antibacterial BIVO4 co-catalysts H_(2)O_(2)production microenvironment PHOTOELECTROCATALYSIS
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Investigation of the production of ^(152)Tb and ^(155)Tb terbium radioisotopes with europium targets
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作者 C.Yalçın 《Nuclear Science and Techniques》 2026年第2期183-193,共11页
In recent years,terbium radioisotopes have been investigated for their potential therapeutic and diagnostic applications in nuclear medicine.This study aimed to investigate the production of ^(152) Tb and ^(155) Tb by... In recent years,terbium radioisotopes have been investigated for their potential therapeutic and diagnostic applications in nuclear medicine.This study aimed to investigate the production of ^(152) Tb and ^(155) Tb by alpha-induced reactions in detail,with a specific focus on determining the optimum production parameters and testing existing nuclear models.Given the limited number of experiments conducted on reactions related to terbium isotope production,it is necessary to perform theoretical calculations of cross sections over a wide energy range to gain a detailed understanding of terbium isotope production.To achieve this objective,the cross sections of the ^(151)Eu(α,n)^(154) Tb reactions were calculated up to 60 MeV using the TALYS computer code with 432 different combinations of optical model parameters,level density,and strength function models.The theoretical reaction cross-section results were compared with the experimental results in the literature.The best input parameters were determined using the Threshold Logic Unit method,and these parameters were used in all isotope production calculations.Once the optimal model combination was determined,the total activity production and isotopic fraction of ^(152) Tb and ^(155) Tb isotopes were calculated in detail for beam energies of 17–50 MeV,different irradiation times,and varying ^(151) Eu and ^(153) Eu target thicknesses. 展开更多
关键词 Terbium radioisotopes Medical isotope production Alpha-induced reactions Cross section Threshold logic unit method
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ZFJ signs order for a spunlace production line
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作者 Niu Fang Qiu Shuchen 《China Textile》 2026年第1期11-11,共1页
On November 26th,Zhengzhou Textile Machinery Co.,Ltd.(hereinafter referred to as"ZFJ")signed an order for a high-speed intelligent wide-width wetmethod spunlace production line with Hubei Lijie New Material ... On November 26th,Zhengzhou Textile Machinery Co.,Ltd.(hereinafter referred to as"ZFJ")signed an order for a high-speed intelligent wide-width wetmethod spunlace production line with Hubei Lijie New Material Technology Co.,Ltd.(hereinafter referred to as"Hubei Lijie").This cooperation marks a further consolidation of ZFJ's leading position in the nonwoven fabric equipment market in Hubei Province and lays a solid foundation for deeper cooperation between the two companies in the future. 展开更多
关键词 deep cooperation wet method nonwoven fabric equipment spunlace production line high speed intelligent nonwoven fabric equipment market
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Efficient cyclohexane dehydrogenation over Pt/B–ZrO_(2)for H_(2)production
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作者 Lipeng Guo Jihui Yao +1 位作者 Xiaojun Bao Haibo Zhu 《Green Energy & Environment》 2026年第1期105-118,共14页
The efficient storage and release of H_(2)are pivotal for the advancement of hydrogen energy technologies.Cyclohexane,as a promising liquid organic hydrogen carrier(LOHC),provides a safe and practical solution for H_(... The efficient storage and release of H_(2)are pivotal for the advancement of hydrogen energy technologies.Cyclohexane,as a promising liquid organic hydrogen carrier(LOHC),provides a safe and practical solution for H_(2)storage.However,the performance limitations of dehydrogenation catalysts have hindered the rapid development of LOHC technology.In this study,we successfully developed boron-modified Pt/ZrO_(2)catalysts,which exhibit exceptional catalytic performance in cyclohexane dehydrogenation.The optimal boron content is determined to be 0.5 wt.%,with the Pt/0.5B–ZrO_(2)catalyst achieving high turnover frequency(TOF)of 10,627.3 mol_(H_(2))·mol_(Pt)^(−1)·h^(−1)and benzene selectivity of 99%at 295°C.The catalyst also demonstrates H_(2)evolution rate of 908 mmol·g_(Pt)^(−1)·min^(−1)and low deactivation rate of 0.0043 h^(−1).Remarkably,the catalyst displays outstanding stability and regeneration performance,maintaining its activity without significant loss during a 60-h dehydrogenation reaction and retaining a cyclohexane conversion of 77.2%after 10 consecutive cycles.Comprehensive characterization techniques,including XPS,CO-FTIR,NH_(3)-TPD,H_(2)-TPD,Benzene-TPD,and Py-IR,reveals that boron modification reduces the electron density of Pt,generating abundant electron-deficient Pt atoms.These electron-deficient Pt atoms enhance H_(2)adsorption and accelerate benzene desorption,effectively preventing coke formation from deep benzene dehydrogenation,which is responsible for the high catalytic performance of the Pt/0.5B–ZrO_(2)catalyst.These findings offer a valuable strategy for optimizing dehydrogenation catalysts in LOHC technologies,addressing a critical bottleneck in the development of this essential energy storage solution. 展开更多
关键词 Liquid organic hydrogen carriers Cyclohexane dehydrogenation H_(2)production Boron-modified ZrO_(2) Electron-deficient Pt atoms
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Optimizing CO production in electrocatalytic CO_(2)reduction via electron accumulation at Ni sites in Ni_(3)ZnC_(0.7)/Ni on N-doped carbon nanofibers
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作者 Min Wang Ge Bai +6 位作者 Luwei Peng Lulu Li Yadan Yu Wenyi Li Nianjun Yang Daniil I.Kolokolove Jinli Qiao 《Green Energy & Environment》 2026年第1期258-268,共11页
The electrocatalytic reduction of carbon dioxide(CO_(2)RR)to valuable products presents a promising solution for addressing global warming and enhancing renewable energy storage.Herein,we construct a novel Ni_(3)ZnC_(... The electrocatalytic reduction of carbon dioxide(CO_(2)RR)to valuable products presents a promising solution for addressing global warming and enhancing renewable energy storage.Herein,we construct a novel Ni_(3)ZnC_(0.7)/Ni heterostructure electrocatalyst,using an electrospinning strategy to prepare metal particles uniformly loaded on nitrogen-doped carbon nanofibers(CNFs).The incorporation of zinc(Zn)into nickel(Ni)catalysts optimizes the adsorption of CO_(2)intermediates,balancing the strong binding affinity of Ni with the comparatively weaker affinity of Zn,which mitigates over-activation.The electron transfer within the Ni_(3)ZnC_(0.7)/Ni@CNFs system facilitates rapid electron transfer to CO_(2),resulting in great performance with a faradaic efficiency for CO(FECO)of nearly 90%at−0.86 V versus the reversible hydrogen electrode(RHE)and a current density of 17.51 mA cm^(−2)at−1.16 V versus RHE in an H-cell.Furthermore,the catalyst exhibits remarkable stability,maintaining its crystal structure and morphology after 50 h of electrolysis.Moreover,the Ni_(3)ZnC_(0.7)/Ni@CNFs is used in the membrane electrode assembly reactor(MEA),which can achieve a FECO of 91.7%at a cell voltage of−3 V and a current density of 200 mA cm−2 at−3.9 V,demonstrating its potential for practical applications in CO_(2)reduction. 展开更多
关键词 CO_(2)electroreduction CO production Ni_(3)ZnC_(0.7)/Ni Heterostructure Membrane electrode assembly
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Tracing production costs and carbon footprint in the primary textile industry
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《China Textile》 2025年第4期12-12,共1页
The new edition of the International Production Cost Comparison (IPCC) from ITMF has been published.The report benchmarks manufacturing costs for a range of textile products along the primary textile value chain,disag... The new edition of the International Production Cost Comparison (IPCC) from ITMF has been published.The report benchmarks manufacturing costs for a range of textile products along the primary textile value chain,disaggregated by key cost components at each production stage. 展开更多
关键词 international production cost comparison PCC carbon footprint cost components production costs textile products textile industry production cost
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An intelligent separated zone oil production technology based on electromagnetic coupling principle
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作者 YANG Qinghai LIAO Chenglong +5 位作者 JIA Deli ZHU Yingjun YU Chuan KONG Lingwei YU Yang DU Kai 《Petroleum Exploration and Development》 2025年第1期230-244,共15页
To address the challenges associated with existing separated zone oil production technologies,such as incompatibility with pump inspection operations,short effective working life,and poor communication reliability,an ... To address the challenges associated with existing separated zone oil production technologies,such as incompatibility with pump inspection operations,short effective working life,and poor communication reliability,an innovative electromagnetic coupling intelligent zonal oil production technology has been proposed.The core and accessory tools have been developed and applied in field tests.This technology employs a pipe string structure incorporation a release sub,which separates the production and allocation pipe strings.When the two strings are docked downhole,electromagnetic coupling enables close-range wireless transmission of electrical power and signals between the strings,powering multiple downhole intelligent production allocators(IPAs)and enabling two-way communication.Core tools adapted to the complex working conditions downhole were developed,including downhole electricity&signal transmission equipment based on electromagnetic coupling(EST),IPAs,and ground communication controllers(GCCs).Accessory tools,including large-diameter release sub anchor and cable-crossing packers,have also been technically finalized.Field tests conducted on ten wells in Daqing Oilfield demonstrated that the downhole docking of the two strings was convenient and reliable,and the EST worked stably.Real-time monitoring of flow rate,pressure and temperature in separate layers and regulation of zonal fluid production were also achieved.This technology has enhanced reservoir understanding and achieved practical production results of increased oil output with reduced water cut. 展开更多
关键词 separated zone oil production electromagnetic coupling wireless transmission of electrical power wireless transmission of signal real-time downhole monitoring collaborative regulation of injection and production oil production stabilization and water cut control
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Key parameters and evaluation methods for large-scale production of lacustrine shale oil 被引量:2
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作者 KUANG Lichun WU Songtao +3 位作者 XING Haoting WU Kunyu SHEN Yue WANG Zhenlin 《Petroleum Exploration and Development》 2025年第4期883-893,共11页
Based on the analysis of typical lacustrine shale oil zones in China and their geological characteristics,this study elucidates the fundamental differences between the enrichment patterns of shale oil sweet spots and ... Based on the analysis of typical lacustrine shale oil zones in China and their geological characteristics,this study elucidates the fundamental differences between the enrichment patterns of shale oil sweet spots and conventional oil and gas.The key parameters and evaluation methods for assessing the large-scale production potential of lacustrine shale oil are proposed.The results show that shale oil is a petroleum resource that exists in organic-rich shale formations,in other words,it is preserved in its source bed,following a different process of generation-accumulation-enrichment from conventional oil and gas.Thus,the concept of“reservoir”seems to be inapplicable to shale oil.In China,lacustrine shale oil is distributed widely,but the geological characteristics and sweet spots enrichment patterns of shale oil vary significantly in lacustrine basins where the water environment and the tectonic evolution and diagenetic transformation frameworks are distinct.The core of the evaluation of lacustrine shale oil is“sweet spot volume”.The key factors for evaluating the large-scale production of continental shale oil are the oil storage capacity,oil-bearing capacity and oil producing capacity.The key parameters for evaluating these capacities are total porosity,oil content,and free oil content,respectively.It is recommended to determine the total porosity of shale by combining helium porosity measurement with nuclear magnetic resonance(NMR)method,the oil content of key layers by using organic solvent extraction,NMR method and high pressure mercury intrusion methods,and the free oil content by using NMR fluid distribution secondary spectral stripping decomposition and logging.The research results contribute supplemental insights on continental shale oil deliverability in China,and provide a scientific basis for the rapid exploration and large-scale production of lacustrine shale oil. 展开更多
关键词 sweet spot oil content free oil nano-pore total porosity evaluation of oil production capacity large-scale production unconventional oil and gas lacustrine shale oil
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Electrical and aging modeling of PEM water electrolyzers for sustainable hydrogen production:Insights into behavior,degradation,and reliability
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作者 Haniyeh Marefat Francois Auger +1 位作者 Jean-Christophe Olivier Mohammed Rharda 《Global Energy Interconnection》 2025年第4期537-553,共17页
Proton Exchange Membrane Water Electrolyzers(PEMWE)are efficient and sustainable hydrogen production devices.This article analyzes their static and dynamic electrical models integrated with degradation mechanisms.Stat... Proton Exchange Membrane Water Electrolyzers(PEMWE)are efficient and sustainable hydrogen production devices.This article analyzes their static and dynamic electrical models integrated with degradation mechanisms.Static models reveal steady-state behavior,while dynamic models capture transient responses to input variations.The developed modeling approach combines the activation and diffusion phenomena,resulting in a novel PEMWE model that closely reflects real-world conditions and enables fast simulations.The electrical model is integrated with the aging model through two key ratios,surface degradation ratio and membrane degradation ratio,which characterize degradation mechanisms affecting electrode and membrane performance.The linear model using second-order Taylor approximation enables the development of a diagnosis approach that can contribute to estimating the remaining useful life of PEMWEs.By associating aging models with electrical models through the proposed ratios,a deeper understanding is achieved regarding how degra-dation phenomena evolve and influence electrolyzer efficiency and durability.The integrated framework enables predictive maintenance strategies,making it valuable for industrial hydrogen production applications. 展开更多
关键词 PEM water electrolyzer Polarization curve Electrical modeling Linear polarization curve Aging modeling DEGRADATION RELIABILITY Hydrogen production Maximum production point
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Recent advances in scalable exosome production:Challenges and innovations
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作者 Hanfei Chen Qingfeng Li 《Chinese Journal of Plastic and Reconstructive Surgery》 2025年第3期149-163,共15页
Exosomes,nanosized extracellular vesicles(30-150 nm),play a crucial role in intercellular communication and are promising biomarkers and therapeutic agents in oncology,neurodegenerative disorders,and immunotherapy.How... Exosomes,nanosized extracellular vesicles(30-150 nm),play a crucial role in intercellular communication and are promising biomarkers and therapeutic agents in oncology,neurodegenerative disorders,and immunotherapy.However,their widespread clinical adoption is constrained by challenges in scalable production,efficient purification,and regulatory standardization.This review critically evaluates recent advancements in exosome bioprocessing,including cell source optimization,culture refinement,and next-generation isolation technologies such as microfluidic microarrays and EXODUS systems.Additionally,we address the limitations of current exosome standardization efforts and propose harmonized protocols to enhance reproducibility.Future research should focus on integrating scalable bioreactor-based systems and artificial intelligence-driven quality control frameworks to accelerate exosome applications in precision medicine and regenerative therapy. 展开更多
关键词 EXOSOME production Scale-up production Isolation and purification STANDARDIZATION
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Hot melt emulsification shear method for solid lipid-based suspension:from laboratory-scale to pilot-scale production
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作者 Chao Li Wenqing Xie +3 位作者 Liwen Yuan Mubbashar Abbas Dongmei Chen Shuyu Xie 《Animal Diseases》 2025年第2期235-247,共13页
The clinical application of solid lipid particles(SLPs)is hampered due to the need for advanced nano/micro-suspension production technology.This research aims to establish a pilot-scale production line employing high-... The clinical application of solid lipid particles(SLPs)is hampered due to the need for advanced nano/micro-suspension production technology.This research aims to establish a pilot-scale production line employing high-speed shears as emulsification equipment.The primary purpose is to manufacture nano/micro-suspensions using solid lipid particles(SLPs).The study also exhaustively introduces and analyzes the regulatory schemes for process parameters and formulations at various stages of production.The process and formulation endured optimization through orthog-onal or single-factor tests at various production steps:laboratory research,small-scale trial production,and pilot production.Quality standards for the product were determined,and key parameters were obtained at each stage.The laboratory research demonstrated that the optimal SLPs comprised 15 mL 3%polyvinyl alcohol(PVA)per 1.0 g tilmicosin and 2.5 g carnauba wax(WAX).During small-scale production,modifications were made to the volume of the aqueous phase,emulsifier concentration,and emulsification strength,setting them to 16 mL,5%,and 2200 r/min,respectively.In the pilot production stage,the shear time was considered optimal at eight min.The impurity,content,polydispersion coefficient(PDI),and size of the pilot product were<3%,5%,0385 and 2.64μm,respectively.Among the several parameters studied,heating temperature,drug-lipid ratio,and emulsifier concentration were identified as the main factors affecting product quality,and they were regulated at 100℃,1:3,and 5%,respectively.A novel hot melt emulsification shear method aided the development of a new solid lipid-based suspension from its preliminary stages in the laboratory to pilot production.This innovation is expected to enhance solid lipid-based suspensions'industrial evolution extensively. 展开更多
关键词 Laboratory research Small-scale production Pilot production Quality evaluation Solid lipid particles
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SGP-GCN:A Spatial-Geological Perception Graph Convolutional Neural Network for Long-Term Petroleum Production Forecasting
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作者 Xin Liu Meng Sun +1 位作者 Bo Lin Shibo Gu 《Energy Engineering》 2025年第3期1053-1072,共20页
Long-termpetroleum production forecasting is essential for the effective development andmanagement of oilfields.Due to its ability to extract complex patterns,deep learning has gained popularity for production forecas... Long-termpetroleum production forecasting is essential for the effective development andmanagement of oilfields.Due to its ability to extract complex patterns,deep learning has gained popularity for production forecasting.However,existing deep learning models frequently overlook the selective utilization of information from other production wells,resulting in suboptimal performance in long-term production forecasting across multiple wells.To achieve accurate long-term petroleum production forecast,we propose a spatial-geological perception graph convolutional neural network(SGP-GCN)that accounts for the temporal,spatial,and geological dependencies inherent in petroleum production.Utilizing the attention mechanism,the SGP-GCN effectively captures intricate correlations within production and geological data,forming the representations of each production well.Based on the spatial distances and geological feature correlations,we construct a spatial-geological matrix as the weight matrix to enable differential utilization of information from other wells.Additionally,a matrix sparsification algorithm based on production clustering(SPC)is also proposed to optimize the weight distribution within the spatial-geological matrix,thereby enhancing long-term forecasting performance.Empirical evaluations have shown that the SGP-GCN outperforms existing deep learning models,such as CNN-LSTM-SA,in long-term petroleum production forecasting.This demonstrates the potential of the SGP-GCN as a valuable tool for long-term petroleum production forecasting across multiple wells. 展开更多
关键词 Petroleum production forecast graph convolutional neural networks(GCNs) spatial-geological rela-tionships production clustering attention mechanism
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Novel 3D-on-2D g-C_(3)N_(4)/AgIn_(x)S_(y)heterojunction photocatalyst for simultaneous and stoichiometric production of H_(2)and H_(2)O_(2)from water splitting under visible light
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作者 Hualin Jiang Wenxi Ye +4 位作者 Huitao Zhen Xubiao Luo Vyacheslav Fominski Long Ye Pinghua Chen 《Chinese Chemical Letters》 2025年第2期448-453,共6页
Photocatalytic H_(2)production from water splitting is a promising candidate for solving the increasing energy crisis and environmental issues.Herein we report a novel g-C_(3)N_(4)/Ag In_(x)S_(y)S-scheme heterojunctio... Photocatalytic H_(2)production from water splitting is a promising candidate for solving the increasing energy crisis and environmental issues.Herein we report a novel g-C_(3)N_(4)/Ag In_(x)S_(y)S-scheme heterojunction photocatalyst for water splitting into stoichiometric H_(2)and H_(2)O_(2)under visible light.The catalyst was prepared by depositing 3D bimetallic sulfide(Ag In_(x)S_(y))nanotubes onto 2D g-C_(3)N_(4)nanosheets.Owing to the special 3D-on-2D configuration,the photogenerated carriers could be rapidly transferred and effectively separated through the abundant interfacial heterostructures to avoid recombination,and therefore excellent performance for visible light-driven water splitting could be obtained,with a 24-h H_(2)evolution rate up to 237μmol g^(-1)h^(-1).Furthermore,suitable band alignment enables simultaneous H_(2)and H_(2)O_(2)production in a 1:1 stoichiometric ratio.H_(2)and H_(2)O_(2)were evolved on the conduction band of g-C_(3)N_(4)and on the valance band of Ag In_(x)S_(y),respectively.The novel 3D-on-2D configuration for heterojunction construction proposed in this work provided alternative research ideas toward photocatalytic reaction. 展开更多
关键词 Photocatalysis Water splitting g-C3N4 Silver indium sulfide H_(2)production H_(2)O_(2)production
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Production characteristics of light nuclei, hypertritons, and Ω‑hypernuclei in Pb+Pb collisions at √S_(NN)=5.02TeV
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作者 Rui‑Qin Wang Xin‑Lei Hou +2 位作者 Yan‑Hao Li Jun Song Feng‑Lan Shao 《Nuclear Science and Techniques》 2025年第10期123-144,共22页
This study aims to investigate the production of light nuclei,hypertritons,and Ω-hypernuclei in Pb+Pb collisions at √S_(NN)=5.02TeV TeV using a modified analytical nucleon coalescence model with hyperons.To this end... This study aims to investigate the production of light nuclei,hypertritons,and Ω-hypernuclei in Pb+Pb collisions at √S_(NN)=5.02TeV TeV using a modified analytical nucleon coalescence model with hyperons.To this end,the momentum distributions of two bodies coalescing into dibaryon states and of three bodies coalescing into tribaryon states are derived.Available data on coalescence factors B_(2) and B_(3),transverse momentum spectra,averaged transverse momenta,yield rapidity densities,and yield ratios of the deuteron,antihelium-3,antitriton,and hypertriton measured by the ALICE collaboration are explained.Productions of different species of Ω-hypernuclei H(pΩ^(−)),H(nΩ^(−)),and H(pnΩ^(−))are predicted.Particularly,the production correlations of different light(hyper-)nuclei are studied,and two groups of interesting observables-the averaged transverse momentum ratios of light(hyper-)nuclei to protons(hyperons)and their corresponding yield ratios-are studied.The averaged transverse momentum ratio group exhibits a reverse hierarchy of the nucleus size,and the yield raito group is sensitive to the nucleus production mechanism as well as the size of the nucleus. 展开更多
关键词 Light nucleus production Hypernucleus production Coalescence model Relativistic heavy ion collision
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The Sivers Asymmetry of Vector Meson Production in Semi-Inclusive Deep Inelastic Scattering
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作者 Yongjie Deng Tianbo Liu Ya-Jin Zhou 《Chinese Physics Letters》 2025年第6期38-51,共14页
The transverse single-spin asymmetry forρ^(0) production in semi-inclusive deep inelastic scattering was recently reported by the COMPASS Collaboration.Using the Sivers function extracted from pion and kaon productio... The transverse single-spin asymmetry forρ^(0) production in semi-inclusive deep inelastic scattering was recently reported by the COMPASS Collaboration.Using the Sivers function extracted from pion and kaon productions,we perform a calculation of the Sivers asymmetry within the transverse momentum-dependent factorization.Our results are consistent with the COMPASS data,supporting the universality of the Sivers function in the semi-inclusive deep inelastic scattering process for different final-state hadrons within current experimental uncertainties.While different parametrizations of the Sivers function from global analyses allow describing the data equally well,we obtain very different predictions on the Sivers asymmetry ofρand K^(*)productions at electron-ion colliders,which therefore are expected to provide further constraints. 展开更多
关键词 Sivers asymmetry transverse single spin asymmetry pion kaon productionswe sivers function semi inclusive deep inelastic scattering compass datasupporting calculation sivers asymmetry vector meson production
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