BACKGROUND Acute kidney injury(AKI)after coronary artery bypass graft(CABG)surgery is associated with significant morbidity and mortality.This retrospective study aimed to establish a risk score for postoperative AKI ...BACKGROUND Acute kidney injury(AKI)after coronary artery bypass graft(CABG)surgery is associated with significant morbidity and mortality.This retrospective study aimed to establish a risk score for postoperative AKI in a Chinese population.METHODS A total of 1138 patients undergoing CABG were collected from September 2018 to May 2020 and divided into a derivation and validation cohort.AKI was defined according to the Kidney Disease Improving Global Outcomes(KDIGO)criteria.Multivariable logistic regression analysis was used to determine the independent predictors of AKI,and the predictive ability of the model was determined using a receiver operating characteristic(ROC)curve.RESULTS The incidence of cardiac surgery–associated acute kidney injury(CSA-AKI)was 24.17%,and 0.53%of AKI patients required dialysis(AKI-D).Among the derivation cohort,multivariable logistic regression showed that age≥70 years,body mass index(BMI)≥25 kg/m2,estimated glomerular filtration rate(eGFR)≤60 mL/min per 1.73 m2,ejection fraction(EF)≤45%,use of statins,red blood cell transfusion,use of adrenaline,intra-aortic balloon pump(IABP)implantation,postoperative low cardiac output syndrome(LCOS)and reoperation for bleeding were independent predictors.The predictive model was scored from 0 to32 points with three risk categories.The AKI frequencies were as follows:0-8 points(15.9%),9-17 points(36.5%)and≥18 points(90.4%).The area under of the ROC curve was 0.730(95%CI:0.691-0.768)in the derivation cohort.The predictive index had good discrimination in the validation cohort,with an area under the curve of 0.735(95%CI:0.655-0.815).The model was well calibrated according to the Hosmer-Lemeshow test(P=0.372).CONCLUSION The performance of the prediction model was valid and accurate in predicting KDIGO-AKI after CABG surgery in Chinese patients,and could improve the early prognosis and clinical interventions.展开更多
Since the International Conference on Population and Development(ICPD)in 1994,global initiatives like the Millennium Development Goals(MDGs)and Sustain-able Development Goals(SDGs)have evolved from simple population c...Since the International Conference on Population and Development(ICPD)in 1994,global initiatives like the Millennium Development Goals(MDGs)and Sustain-able Development Goals(SDGs)have evolved from simple population control to a comprehensive focus on human rights,social justice,and sustainable development,emphasizing social equity,gender equality,sustainability,and global cooperation.This paper reviews China’s response to these initiatives,focusing on the ICPD Pro-gram of Action and SDGs,and assesses how its demographic transformation over the past 30 years has influenced global population trends and other development areas.We find that China has actively embraced these global principles,integrat-ing them into its national strategy through improved fertility policies,population structure optimization,and addressing population aging.These measures have sig-nificantly reshaped China’s demographic landscape and impacted global population dynamics.The paper also highlights China’s substantial progress in health and well-being,life expectancy,gender equality,social equity,and climate action.To address its rapid population aging,China has developed robust social security systems,par-ticularly in pensions and health insurance.China’s experience in urbanization and economic growth has provided valuable insights for global development.Addition-ally,China’s efforts have advanced education,improved women’s rights,and sup-ported disadvantaged groups,contributing to the undertaking of global sustainable development.We conclude that China’s efforts in implementing international action plans since the ICPD have laid a strong foundation for achieving global SDGs,that China has become a role model for the international community in the domain of population and development,and that China will continuously contribute signifi-cantly to global development agendas in the years to come.展开更多
The impact of South-South cooperation(SSC)has been bolstered in the context of implementing the International Conference on Population and Development(ICPD)Programme of Action.In the past 25 years since ICPD in 1994,r...The impact of South-South cooperation(SSC)has been bolstered in the context of implementing the International Conference on Population and Development(ICPD)Programme of Action.In the past 25 years since ICPD in 1994,remarkable progress and achievements have been made in promoting SSC in population and develop-ment.China has been committed to working with developing countries,UN agen-cies and international organizations to advance ICPD under the framework of SSC.As the landscape of international development assistance has been changing and the ICPD remains as an unfinished agenda,the SSC has increasingly recognized the importance of effective financial inclusion policy in the implementation of the ICPD and the 2030 Agenda for Sustainable Development.The international community has recently identified seven strategic priority areas for SSC in the next few years,i.e.,(1)population dynamics and development;(2)universal access to reproduc-tive health and family planning services;(3)women’s,children’s and adolescents’health;(4)healthy ageing;(5)migration;(6)health and poverty alleviation;and(7)ending sexual and gender-based violence.The institutionalization and operation-alization remain as critical challenges,and special attention needs to be given to address these issues.Stronger political commitments,enhanced capacity building,better coordination and partnerships establishment of the SSC Center of Excellence,adequate resource mobilization and more evidence-based researches and systematic evaluation are recommended as future strategies for further promoting the SSC in population and development.展开更多
基金supported by National Natural S cience Foundation of China(81570373)。
文摘BACKGROUND Acute kidney injury(AKI)after coronary artery bypass graft(CABG)surgery is associated with significant morbidity and mortality.This retrospective study aimed to establish a risk score for postoperative AKI in a Chinese population.METHODS A total of 1138 patients undergoing CABG were collected from September 2018 to May 2020 and divided into a derivation and validation cohort.AKI was defined according to the Kidney Disease Improving Global Outcomes(KDIGO)criteria.Multivariable logistic regression analysis was used to determine the independent predictors of AKI,and the predictive ability of the model was determined using a receiver operating characteristic(ROC)curve.RESULTS The incidence of cardiac surgery–associated acute kidney injury(CSA-AKI)was 24.17%,and 0.53%of AKI patients required dialysis(AKI-D).Among the derivation cohort,multivariable logistic regression showed that age≥70 years,body mass index(BMI)≥25 kg/m2,estimated glomerular filtration rate(eGFR)≤60 mL/min per 1.73 m2,ejection fraction(EF)≤45%,use of statins,red blood cell transfusion,use of adrenaline,intra-aortic balloon pump(IABP)implantation,postoperative low cardiac output syndrome(LCOS)and reoperation for bleeding were independent predictors.The predictive model was scored from 0 to32 points with three risk categories.The AKI frequencies were as follows:0-8 points(15.9%),9-17 points(36.5%)and≥18 points(90.4%).The area under of the ROC curve was 0.730(95%CI:0.691-0.768)in the derivation cohort.The predictive index had good discrimination in the validation cohort,with an area under the curve of 0.735(95%CI:0.655-0.815).The model was well calibrated according to the Hosmer-Lemeshow test(P=0.372).CONCLUSION The performance of the prediction model was valid and accurate in predicting KDIGO-AKI after CABG surgery in Chinese patients,and could improve the early prognosis and clinical interventions.
文摘Since the International Conference on Population and Development(ICPD)in 1994,global initiatives like the Millennium Development Goals(MDGs)and Sustain-able Development Goals(SDGs)have evolved from simple population control to a comprehensive focus on human rights,social justice,and sustainable development,emphasizing social equity,gender equality,sustainability,and global cooperation.This paper reviews China’s response to these initiatives,focusing on the ICPD Pro-gram of Action and SDGs,and assesses how its demographic transformation over the past 30 years has influenced global population trends and other development areas.We find that China has actively embraced these global principles,integrat-ing them into its national strategy through improved fertility policies,population structure optimization,and addressing population aging.These measures have sig-nificantly reshaped China’s demographic landscape and impacted global population dynamics.The paper also highlights China’s substantial progress in health and well-being,life expectancy,gender equality,social equity,and climate action.To address its rapid population aging,China has developed robust social security systems,par-ticularly in pensions and health insurance.China’s experience in urbanization and economic growth has provided valuable insights for global development.Addition-ally,China’s efforts have advanced education,improved women’s rights,and sup-ported disadvantaged groups,contributing to the undertaking of global sustainable development.We conclude that China’s efforts in implementing international action plans since the ICPD have laid a strong foundation for achieving global SDGs,that China has become a role model for the international community in the domain of population and development,and that China will continuously contribute signifi-cantly to global development agendas in the years to come.
文摘The impact of South-South cooperation(SSC)has been bolstered in the context of implementing the International Conference on Population and Development(ICPD)Programme of Action.In the past 25 years since ICPD in 1994,remarkable progress and achievements have been made in promoting SSC in population and develop-ment.China has been committed to working with developing countries,UN agen-cies and international organizations to advance ICPD under the framework of SSC.As the landscape of international development assistance has been changing and the ICPD remains as an unfinished agenda,the SSC has increasingly recognized the importance of effective financial inclusion policy in the implementation of the ICPD and the 2030 Agenda for Sustainable Development.The international community has recently identified seven strategic priority areas for SSC in the next few years,i.e.,(1)population dynamics and development;(2)universal access to reproduc-tive health and family planning services;(3)women’s,children’s and adolescents’health;(4)healthy ageing;(5)migration;(6)health and poverty alleviation;and(7)ending sexual and gender-based violence.The institutionalization and operation-alization remain as critical challenges,and special attention needs to be given to address these issues.Stronger political commitments,enhanced capacity building,better coordination and partnerships establishment of the SSC Center of Excellence,adequate resource mobilization and more evidence-based researches and systematic evaluation are recommended as future strategies for further promoting the SSC in population and development.
