A kind of method of modal identification subject to ambient excitation is presented. A new synthesis stationary signal based on structural response wavelet transform and wavelet coefficient processes co-integration is...A kind of method of modal identification subject to ambient excitation is presented. A new synthesis stationary signal based on structural response wavelet transform and wavelet coefficient processes co-integration is obtained. The new signal instead of structural response is used in identifying the modal parameters of a non- stationary system, combined with the method of modal identification under stationary random excitation-the NExT method and the adjusted continuous least square method. The numerical results show that the method can eliminate the non-stationarity of structural response subject to non-stationary random excitation to a great extent, and is highly precise and robust.展开更多
Based on the statistical data of Huixian from 1992 to 2010, we analyze the long-term and short-term relationship between Huixian's methane energy development and GDP by using co-integration test and error correcti...Based on the statistical data of Huixian from 1992 to 2010, we analyze the long-term and short-term relationship between Huixian's methane energy development and GDP by using co-integration test and error correction model. The empirical results show that there is a long-term equilibrium relationship between methane energy and GDP in the city of Huixian, and which is the one-way Granger causality of methane and GDP. In conclusion, the paper puts forward some steps about spurring economic growth, methane development and utilization in Huixian.展开更多
This article describes a study by co-integration test and Granger causality test on the relationships between China's services trades and employment using the data of services trade from the WTO website and the em...This article describes a study by co-integration test and Granger causality test on the relationships between China's services trades and employment using the data of services trade from the WTO website and the employment data from China Statistic Yearbook for the years from 1982 to 2003. Co-integration test showed that 1% increase in export value and import value of services created respectively 0.205% and 0.068 7% more job opportunities in the service sector. Both export and import of services impacted positively on employment in service industry, and export did more than import. However, in the short run, the impacts of services export and import on employment in service industry were both very small, though positive; and the impacts of employment in service industry on both export and import of services were very big, but not stable. Granger causality test indicated that employment in service industry was a Granger cause of services export. The findings highlight the importance of facilitating services import and reducing import barriers, and suggest that the competitiveness of China's labor- intensive services trade can be exploited to boost services export and help employment in service sector, and that the structure of services trade should be optimized by shifting from labor-intensive to knowledge-and technology-intensive services thus to enhance China's competitiveness of services export.展开更多
A vector autoregressive model was developed for a sample of container carrier time charter rates. Although the series of time charter rates are themselves found non-stationary, thus precluding the use of many modeling...A vector autoregressive model was developed for a sample of container carrier time charter rates. Although the series of time charter rates are themselves found non-stationary, thus precluding the use of many modeling methodologies, evidence provided by co-integration tests points to the existence of stable long-term relationships between the series. An assessment of the forecasts derived from the model suggests that the spec-ification of these long-term relationships does not improve the accuracy of long-term forecasts. These results are interpreted as a corroboration of the efficient market hypothesis.展开更多
Koyna region, a seismically active region, has many time series observations such as seismicity, reservoir water levels, and many bore well water levels. One of these series is used to predict others since these param...Koyna region, a seismically active region, has many time series observations such as seismicity, reservoir water levels, and many bore well water levels. One of these series is used to predict others since these parameters are interlinked. If these series were stationary, we used correlation analysis. However, it is seen that maximum of these time series are nonstationary. In this case, co-integration method is used that is extracted from econometrics and forecast is possible. We have applied this methodology to study time series of reservoir water levels of this region and we find them to be co-integrated. Therefore, forecast of water levels for one of the reservoir is done from the other as these will never drift apart too much. The outcomes demonstrate that a joint modelling of both data sets based on underlying physics resolves to be sparingly useful for understanding predictability issues in reservoir induced seismicity.展开更多
By applying co-integration analysis,the Granger causality test and an error correction model,the dependency between the energy consumption and the gross domestic product of China was examined.In a further step an anal...By applying co-integration analysis,the Granger causality test and an error correction model,the dependency between the energy consumption and the gross domestic product of China was examined.In a further step an analysis was done to establish a correlation between the economic growth of different industries and China's energy consumption.An evidence-based study showed that a co-integration relationship exists between the gross energy consumption and the GDP of China and that the two variables possess bi-directional causality.The energy consumption for the secondary industry has a markedly stimulative effect to the economic growth.This paper also uses an error correction model(ECM)to explain the short-term behavior of energy demands.展开更多
In recent years,there has been a growing global demand for carbon neutrality and energy efficiency,which are expected to become long-term trends.In the field of architecture,an effective approach to achieve this is to...In recent years,there has been a growing global demand for carbon neutrality and energy efficiency,which are expected to become long-term trends.In the field of architecture,an effective approach to achieve this is to reduce heat loss in buildings.Vacuum insulation panels(VIPs),a type of high-performance insulation material,have been increasingly utilised in the construction industry and have played an increa-singly important role as their performance and manufacturing processes continue to improve.This paper provides a review of the factors affecting the thermal conductivity of VIPs and presents a detailed overview of the research progress on core materials,barrier films,and getters.The current research status of VIPs is summarised,including their thermal conductivity,service life,and thermal bridging effects,as well as their applications in the field of architecture.This review aims to provide a comprehensive understanding for relevant practitioners on the factors influencing the thermal conductivity of VIPs,and based on which,measures can be taken to produce VIPs with lower thermal conductivity and longer service life.展开更多
The purpose of this paper is to puts forward suggestions for the sustainable development of mineral resources by combining the benefit of economy from mineral resources with the introduction of concept of circular eco...The purpose of this paper is to puts forward suggestions for the sustainable development of mineral resources by combining the benefit of economy from mineral resources with the introduction of concept of circular economic development.展开更多
Objective To study the possible relationship between the output of new products in China’s pharmaceutical industry and the investment in research and development(R&D),and to provide a theoretical basis for the de...Objective To study the possible relationship between the output of new products in China’s pharmaceutical industry and the investment in research and development(R&D),and to provide a theoretical basis for the decision-making of relevant enterprises and institutions.Methods The econometric software Stata 14 was used to perform unit root test on the relevant data.Then,a co-integration regression equation was established after stabilization,which was analyzed through co-integration test(E-G two-step method).Results and Conclusion There is a long-term equilibrium and short-term error correction relationship between the output of new products and the investment of R&D funds in China’s pharmaceutical industry.During the lagging periods from 1 to 6,R&D investment is the Granger reason for the output of new products.The investment of R&D funds has a positive effect on the output of new products and the effect is significant.Therefore,more investment should be made in R&D to enhance the output of new products.展开更多
The concept of non-Hermitian mechanics introduces new dimensions to metamaterial research,yet current studies have primarily focused on wave manipulation,neglecting the vibration transmittance characteristics of finit...The concept of non-Hermitian mechanics introduces new dimensions to metamaterial research,yet current studies have primarily focused on wave manipulation,neglecting the vibration transmittance characteristics of finite-size metamaterials with boundary reflections.This paper explores the asymmetric vibration transmittance characteristics of a simply supported NonHermitian Metamaterial Panel(NHMP)with two lossy resonators,under the impact of supersonic aerodynamic forces.By examining the non-Hermiticity of a non-aerodynamically loaded NHMP and a host panel aeroelastic system separately,we demonstrate that the NHMP subjected to supersonic aerodynamic force is a complex non-Hermitian system,exhibiting asymmetric vibration transmittance driven by both the fluid-structure interaction effect and lossy resonators.We theoretically and numerically clarify that an ideal aeroelastic system,such as a host panel aeroelastic system,functions as a non-Hermitian mechanical system due to the fluid-structure interaction effect,with the critical flutter point aligning with the Exceptional Point(EP).The results of this study indicate that at low dynamic pressures,the lossy resonators primarily govern asymmetric vibration transmittance,whereas at high dynamic pressures,the fluid-structure interaction effect becomes the dominant factor.Notably,at the EP,asymmetric vibration transmittance is unaffected by the mass ratio of lossy resonators,which is attributed to the invariance of the operational deflection shapes of the NHMP at the EP.This study offers a novel perspective on panel aeroelastic systems and nonHermitian metamaterials,advancing the field through its comprehensive analyses.展开更多
Objective To study the causal relationship between R&D investment and enterprise performance of domestic pharmaceutical enterprises.Methods Panel data model was adopted for empirical analysis.Results and Conclusio...Objective To study the causal relationship between R&D investment and enterprise performance of domestic pharmaceutical enterprises.Methods Panel data model was adopted for empirical analysis.Results and Conclusion Increasing the R&D investment intensity of pharmaceutical enterprises in the Yangtze River Delta and Zhejiang by 1%will increase their profit margins by 0.79%and 0.46%.On the contrary,if the profit margin increases by 1%,the R&D investment intensity will increase by 0.25%and 0.19%.If the profit margin of pharmaceutical enterprises in Beijing,Tianjin,Hebei,Chengdu,Chongqing and other regions increases by 1%,the R&D investment intensity will increase by 0.14%,0.07%and 0.1%,respectively,which are lower than those in the Yangtze River Delta and Zhejiang.The relationship between R&D investment and enterprise performance of pharmaceutical enterprises in the Yangtze River Delta and Zhejiang Province is Granger causality,showing a two-way positive effect.Profits and R&D investment of pharmaceutical enterprises in Beijing,Tianjin,Hebei,Chengdu,Chongqing and other regions are also Granger causality.But in the Pearl River Delta,profits and R&D investment have not passed the stability test,it is impossible to determine the causality between them.展开更多
Lysosomal dysfunction has been implicated in the progression of colon adenocarcinoma(COAD),yet the prognostic significance and therapeutic potential of lysosome-related genes(LRGs)remain underexplored.In this study,we...Lysosomal dysfunction has been implicated in the progression of colon adenocarcinoma(COAD),yet the prognostic significance and therapeutic potential of lysosome-related genes(LRGs)remain underexplored.In this study,we construct a 6-LRG-based prognostic risk stratification model(DPP7,ADAM8,CD1B,LRP2,ATP6V1C2,and PLAAT3)by integrating LASSO and Cox regression analyses.Stratifying patients based on median risk scores,we demonstrate that high-risk patients exhibit significantly worse clinical outcomes across the TCGA cohort and five independent GEO datasets.Furthermore,this panel outperforms 136 previously published models in terms of predictive accuracy for 1-,3-,and 5-year survival rates.Validation multiplex immunofluorescence using an in-house tissue microarray cohort confirms that the 6-LRG signature serves as an independent prognostic factor.Additionally,high-risk patients exhibit distinct immunosuppressive tumor microenvironment and aggressive malignancy characteristics.Functional depletion of DPP7 significantly inhibits tumor cell proliferation,migration,and metastasis in both in vitro and in vivo settings.Moreover,DPP7 silencing attenuates epithelialemesenchymal transition,as evidenced by the upregulation of E-cadherin and downregulation of N-cadherin,Vimentin,and Snail.In conclusion,this study establishes an LRG-based model for COAD prognostic prediction and nominates DPP7 as a promising therapeutic target for COAD treatment.展开更多
To address the limitations of traditional finite element methods,particularly the continuum assumption and difficulties in tracking the solid-liquid interface,this study introduces a lattice Boltzmann-based mathematic...To address the limitations of traditional finite element methods,particularly the continuum assumption and difficulties in tracking the solid-liquid interface,this study introduces a lattice Boltzmann-based mathematical and physical model to simulate flow and heat transfer in the laser welding molten pool of tin-coated copper used in solar panel busbars(a thin strip or wire of conductive metal embedded on the surface of a solar cell to collect and conduct the electricity generated by the photovoltaic cell).The model incorporates key external forces,including surface tension,solid-liquid interface tension,and recoil pressure.A moving and rotating Gaussian-body heat source is adopted,with temperature treated as an implicit function of enthalpy.Coupled iterative schemes for the temperature and velocity fields are constructed using a dual-distribution function approach with a D3Q15 lattice structure.The model is implemented in Python,utilizing libraries such as NumPy,SciPy,Mayavi,and Matplotlib for computation and visualization.Simulation results reveal that the heat transfer mechanism in the molten pool transitions from pure conduction to conduction-convection due to surface tension effects,leading to the formation of multiple counter-rotating vortex structures.The peak temperature at the pool center reaches 3200 K,with maximum melt depth and width measured at 0.5 and 1.2 mm,respectively.Over time,both penetration depth and melt width increase,though the width exhibits a more pronounced growth.Comparison with experimental thermal cycling data from laser weld joints shows strong agreement,with a maximum error of less than 1%,validating the accuracy of the proposed method.展开更多
This study introduces a novel approach for coupled aeroelastic analysis of panel subjected to supersonic airflow,utilizing Add-On Acoustic Black Hole(AABH)to mitigate panel flutter.Employing Galerkin's method to d...This study introduces a novel approach for coupled aeroelastic analysis of panel subjected to supersonic airflow,utilizing Add-On Acoustic Black Hole(AABH)to mitigate panel flutter.Employing Galerkin's method to discretize aeroelastic equation of panel and leveraging finite element method to derive a reduced discrete model of AABH,this study effectively couples two substructures via interface displacement.Investigation into the interactive force highlights the modal effective mass,frequency discrepancy between oscillation and AABH mode,and modal damping ratio as critical factors influencing individual AABH mode in flutter suppression.The selection of effective AABH modes,closely linked to these factors,directly influences the accuracy of simulations.The results reveal that AABH notably enhances the panel's critical flutter boundary by14.6%,a significant improvement over the 3.6%increase afforded by equivalent mass.Furthermore,AABH outperforms both the tuned mass damper and nonlinear energy sink in flutter suppression efficacy.By adjusting the AABH's geometrical parameters to increase the accumulative modal effective mass within the pertinent frequency range,or choosing a suitable installation position for AABH,its performance in flutter suppression is further optimized.These findings not only underscore the AABH's potential in enhancing aeroelastic stability but also provide a foundation for its optimal design.展开更多
To enhance the resistance of honeycomb sandwich panel against local impact,this study delved into the matching relationship between face sheets and core.An integrated approach,combining experiment,simulation,and theor...To enhance the resistance of honeycomb sandwich panel against local impact,this study delved into the matching relationship between face sheets and core.An integrated approach,combining experiment,simulation,and theoretical methods,was used.Local loading experiments were conducted to validate the accuracy of the finite element model.Furthermore,a control equation was formulated to correlate structural parameters with response modes,and a matching coefficientλ(representing the ratio of core thickness to face sheet thickness)was introduced to establish a link between these parameters and impact characteristics.A demand-driven reverse design methodology for structural parameters was developed,with numerical simulations employed to assess its effectiveness.The results indicate that the proposed theory can accurately predict response modes and key indicators.An increase in theλbolsters the structural indentation resistance while concurrently heightens the likelihood of penetration.Conversely,a decrease in theλimproves the resistance to penetration,albeit potentially leading to significant deformations in the rear face sheet.Numerical simulations demonstrate that the reverse design methodology significantly enhances the structural penetration resistance.Comparative analyses indicate that appropriate matching reduces indentation depth by 27.4% and indentation radius by 41.8%of the proposed structure.展开更多
The increasing demand to decrease manufacturing costs and weight reduction is driving the aircraft industry to change the use of conventional riveted stiffened panels to integral stiffened panels(ISP)for aircraft fuse...The increasing demand to decrease manufacturing costs and weight reduction is driving the aircraft industry to change the use of conventional riveted stiffened panels to integral stiffened panels(ISP)for aircraft fuselage structures.ISP is a relatively new structure in aircraft industries and is considered the most significant development in a decade.These structures have the potential to replace the conventional stiffened panel due to the emergence of manufacturing technology,including welding,high-speed machining(HSM),extruding,and bonding.Although laser beam welding(LBW)and friction stir welding(FSW)have been applied in aircraft companies,many investigations into ISP continue to be conducted.In this review article,the current state of understanding and advancement of ISP structure is addressed.A particular explanation has been given to(a)buckling performance,(b)fatigue performance of the ISP,(c)modeling and simulation aspects,and(d)the impact of manufacturing decisions in welding processes on the final structural behavior of the ISP during service.Compared to riveted panels,machined ISP had a better compressive buckling load,and FSW integral panels had a lower buckling load than riveted panels.Compressive residual stress decreased the stress intensity factor(SIF)rates,slowing down the growth of fatigue cracks as occurred in FSW and LBW ISP.展开更多
Wind tunnel experiment and CFD(computational fluid dynamics)simulation with LES(large eddy simulation)have been conducted to investigate the characteristics of peak wind force coefficients of porous panels mounted on ...Wind tunnel experiment and CFD(computational fluid dynamics)simulation with LES(large eddy simulation)have been conducted to investigate the characteristics of peak wind force coefficients of porous panels mounted on the roofs of high-rise buildings.First,aerodynamic modelling of porous panels was discussed.The relation between pressure loss coefficient and porosity was obtained.Then,a wind tunnel experiment was conducted to measure the wind forces(net wind pressures)acting on solid and porous panels mounted on the roof of a high-rise building.Because it was difficult to measure the pressures on both sides of thin,porous panel at the same location simultaneously,we proposed to use the roof edge pressures near the panel for the panel’s inside-surface pressures.This experimental method was validated by a CFD simulation reproducing the wind tunnel experiment.The characteristics of peak wind force coefficients of porous panels mounted on the roofs of high-rise buildings were made clear.Finally,positive and negative peak wind force coefficients for designing the rooftop porous panels were proposed.展开更多
Cooling system design applicable to more than one photovoltaic(PV)unit may be challenging due to the arrangement and geometry of the modules.Different cooling techniques are provided in this study to regulate the temp...Cooling system design applicable to more than one photovoltaic(PV)unit may be challenging due to the arrangement and geometry of the modules.Different cooling techniques are provided in this study to regulate the temperature of conductive panels that are arranged perpendicular to each other.The model uses two vented cavity systems and one L-shaped channel with ternary nanofluid enhanced non-uniform magnetic field.Their cooling performances and comparative results between different systems are provided.The finite element method is used to conduct a numerical analysis for a range of values of the following:the strength of themagnetic field(Hartmann number(Ha)between 0 and 50),the inclination of the magnetic field(γbetween 0 and 90),and the loading of nanoparticles in the base fluid(ϕbetween 0 and 0.03),taking into account both uniformand non-uniformmagnetic fields.For the L-shaped channel and vented cavities,vortex size is controlled by imposing magnetic field and adjusting its strength.Whether uniform or non-uniform magnetic field is applied affects the cooling performances for different cooling configurations.Temperature drops of the horizontal panel with different magnetic field strengths by using channel cooling,vented cavity-1 and vented cavity-2 systems for uniformmagnetic are 11℃,21.5℃,and 3℃when the reference case of Ha=0 is considered for the same cooling systems.However,they become 9.5℃,13.5℃,and 12.5℃when nonuniform magnetic field is used.In the presence of uniform magnetic field effects and changing its magnitude,the use of cooling channel in vented cavity-1 and vented cavity-2 systems results in temperature drops of 4℃,10.8℃,and 3.8℃for vertical panels.On the other hand,when non-uniform magnetic field effects are present,they become 0.5℃,2.1℃,and 9℃.For L-channel cooling,the average Nu for the horizontal panel is more affected byγ,andNu rises asγrises.With increasing nanoparticle loading of ternary nanofluid,the average panel surface temperature shows a linear drop.For the horizontal panel,the temperature declines for nanofluid at the highest loading are 4℃,10℃,and 12℃as compared to using only base fluid.The values of 5℃,7℃,and 11℃are obtained for the vertical panel.Different cooling systems’performance is estimated using artificial neural networks.The method captures the combined impact of applying non-uniformmagnetic field and nanofluid together on the cooling performancewhile accounting for varied cooling strategies for both panels.展开更多
基金The National Natural Science Foundation of China(No50278017)
文摘A kind of method of modal identification subject to ambient excitation is presented. A new synthesis stationary signal based on structural response wavelet transform and wavelet coefficient processes co-integration is obtained. The new signal instead of structural response is used in identifying the modal parameters of a non- stationary system, combined with the method of modal identification under stationary random excitation-the NExT method and the adjusted continuous least square method. The numerical results show that the method can eliminate the non-stationarity of structural response subject to non-stationary random excitation to a great extent, and is highly precise and robust.
文摘Based on the statistical data of Huixian from 1992 to 2010, we analyze the long-term and short-term relationship between Huixian's methane energy development and GDP by using co-integration test and error correction model. The empirical results show that there is a long-term equilibrium relationship between methane energy and GDP in the city of Huixian, and which is the one-way Granger causality of methane and GDP. In conclusion, the paper puts forward some steps about spurring economic growth, methane development and utilization in Huixian.
文摘This article describes a study by co-integration test and Granger causality test on the relationships between China's services trades and employment using the data of services trade from the WTO website and the employment data from China Statistic Yearbook for the years from 1982 to 2003. Co-integration test showed that 1% increase in export value and import value of services created respectively 0.205% and 0.068 7% more job opportunities in the service sector. Both export and import of services impacted positively on employment in service industry, and export did more than import. However, in the short run, the impacts of services export and import on employment in service industry were both very small, though positive; and the impacts of employment in service industry on both export and import of services were very big, but not stable. Granger causality test indicated that employment in service industry was a Granger cause of services export. The findings highlight the importance of facilitating services import and reducing import barriers, and suggest that the competitiveness of China's labor- intensive services trade can be exploited to boost services export and help employment in service sector, and that the structure of services trade should be optimized by shifting from labor-intensive to knowledge-and technology-intensive services thus to enhance China's competitiveness of services export.
文摘A vector autoregressive model was developed for a sample of container carrier time charter rates. Although the series of time charter rates are themselves found non-stationary, thus precluding the use of many modeling methodologies, evidence provided by co-integration tests points to the existence of stable long-term relationships between the series. An assessment of the forecasts derived from the model suggests that the spec-ification of these long-term relationships does not improve the accuracy of long-term forecasts. These results are interpreted as a corroboration of the efficient market hypothesis.
文摘Koyna region, a seismically active region, has many time series observations such as seismicity, reservoir water levels, and many bore well water levels. One of these series is used to predict others since these parameters are interlinked. If these series were stationary, we used correlation analysis. However, it is seen that maximum of these time series are nonstationary. In this case, co-integration method is used that is extracted from econometrics and forecast is possible. We have applied this methodology to study time series of reservoir water levels of this region and we find them to be co-integrated. Therefore, forecast of water levels for one of the reservoir is done from the other as these will never drift apart too much. The outcomes demonstrate that a joint modelling of both data sets based on underlying physics resolves to be sparingly useful for understanding predictability issues in reservoir induced seismicity.
基金Projects TSFZLXKF2006-3 supported by the China Lixin Risk Management Research Institute Foundation of Shanghai Municipal Education Commission90210035 by the National Natural Science Foundation of China
文摘By applying co-integration analysis,the Granger causality test and an error correction model,the dependency between the energy consumption and the gross domestic product of China was examined.In a further step an analysis was done to establish a correlation between the economic growth of different industries and China's energy consumption.An evidence-based study showed that a co-integration relationship exists between the gross energy consumption and the GDP of China and that the two variables possess bi-directional causality.The energy consumption for the secondary industry has a markedly stimulative effect to the economic growth.This paper also uses an error correction model(ECM)to explain the short-term behavior of energy demands.
文摘In recent years,there has been a growing global demand for carbon neutrality and energy efficiency,which are expected to become long-term trends.In the field of architecture,an effective approach to achieve this is to reduce heat loss in buildings.Vacuum insulation panels(VIPs),a type of high-performance insulation material,have been increasingly utilised in the construction industry and have played an increa-singly important role as their performance and manufacturing processes continue to improve.This paper provides a review of the factors affecting the thermal conductivity of VIPs and presents a detailed overview of the research progress on core materials,barrier films,and getters.The current research status of VIPs is summarised,including their thermal conductivity,service life,and thermal bridging effects,as well as their applications in the field of architecture.This review aims to provide a comprehensive understanding for relevant practitioners on the factors influencing the thermal conductivity of VIPs,and based on which,measures can be taken to produce VIPs with lower thermal conductivity and longer service life.
文摘The purpose of this paper is to puts forward suggestions for the sustainable development of mineral resources by combining the benefit of economy from mineral resources with the introduction of concept of circular economic development.
基金Research on Innovation and Development Strategy of Pharmaceutical Industry in Liaoning Province(2020lslktyb-095).
文摘Objective To study the possible relationship between the output of new products in China’s pharmaceutical industry and the investment in research and development(R&D),and to provide a theoretical basis for the decision-making of relevant enterprises and institutions.Methods The econometric software Stata 14 was used to perform unit root test on the relevant data.Then,a co-integration regression equation was established after stabilization,which was analyzed through co-integration test(E-G two-step method).Results and Conclusion There is a long-term equilibrium and short-term error correction relationship between the output of new products and the investment of R&D funds in China’s pharmaceutical industry.During the lagging periods from 1 to 6,R&D investment is the Granger reason for the output of new products.The investment of R&D funds has a positive effect on the output of new products and the effect is significant.Therefore,more investment should be made in R&D to enhance the output of new products.
基金co-supported by the National Natural Science Foundation of China(Nos.12372170,12402104 and 12072276)the National Science Basic Research Program of Shaanxi Province,China(No.2022JM-047)the 111 Project of China(No.BP0719007)。
文摘The concept of non-Hermitian mechanics introduces new dimensions to metamaterial research,yet current studies have primarily focused on wave manipulation,neglecting the vibration transmittance characteristics of finite-size metamaterials with boundary reflections.This paper explores the asymmetric vibration transmittance characteristics of a simply supported NonHermitian Metamaterial Panel(NHMP)with two lossy resonators,under the impact of supersonic aerodynamic forces.By examining the non-Hermiticity of a non-aerodynamically loaded NHMP and a host panel aeroelastic system separately,we demonstrate that the NHMP subjected to supersonic aerodynamic force is a complex non-Hermitian system,exhibiting asymmetric vibration transmittance driven by both the fluid-structure interaction effect and lossy resonators.We theoretically and numerically clarify that an ideal aeroelastic system,such as a host panel aeroelastic system,functions as a non-Hermitian mechanical system due to the fluid-structure interaction effect,with the critical flutter point aligning with the Exceptional Point(EP).The results of this study indicate that at low dynamic pressures,the lossy resonators primarily govern asymmetric vibration transmittance,whereas at high dynamic pressures,the fluid-structure interaction effect becomes the dominant factor.Notably,at the EP,asymmetric vibration transmittance is unaffected by the mass ratio of lossy resonators,which is attributed to the invariance of the operational deflection shapes of the NHMP at the EP.This study offers a novel perspective on panel aeroelastic systems and nonHermitian metamaterials,advancing the field through its comprehensive analyses.
基金Shenyang Pharmaceutical University Young and Middle aged Teacher Career Development Support PlanPublic Welfare Research Fund for Scientific Undertakings of Liaoning Province in 2022(Soft Science Research Plan)(No.2022JH4/10100040).
文摘Objective To study the causal relationship between R&D investment and enterprise performance of domestic pharmaceutical enterprises.Methods Panel data model was adopted for empirical analysis.Results and Conclusion Increasing the R&D investment intensity of pharmaceutical enterprises in the Yangtze River Delta and Zhejiang by 1%will increase their profit margins by 0.79%and 0.46%.On the contrary,if the profit margin increases by 1%,the R&D investment intensity will increase by 0.25%and 0.19%.If the profit margin of pharmaceutical enterprises in Beijing,Tianjin,Hebei,Chengdu,Chongqing and other regions increases by 1%,the R&D investment intensity will increase by 0.14%,0.07%and 0.1%,respectively,which are lower than those in the Yangtze River Delta and Zhejiang.The relationship between R&D investment and enterprise performance of pharmaceutical enterprises in the Yangtze River Delta and Zhejiang Province is Granger causality,showing a two-way positive effect.Profits and R&D investment of pharmaceutical enterprises in Beijing,Tianjin,Hebei,Chengdu,Chongqing and other regions are also Granger causality.But in the Pearl River Delta,profits and R&D investment have not passed the stability test,it is impossible to determine the causality between them.
基金supported by the Natural Science Foundation of Shandong Province(ZR2021MH110,ZR2020MH257,ZR2020MH323)the National Natural Science Foundation of China(82172339 and 82272410)+1 种基金Major Scientific and Technological Innovation Project of Shandong Province(2021CXGC010603 and 2021CXGC011105)Taishan Scholar Program of Shandong Province(tstp20221156 and tsqn202306346).
文摘Lysosomal dysfunction has been implicated in the progression of colon adenocarcinoma(COAD),yet the prognostic significance and therapeutic potential of lysosome-related genes(LRGs)remain underexplored.In this study,we construct a 6-LRG-based prognostic risk stratification model(DPP7,ADAM8,CD1B,LRP2,ATP6V1C2,and PLAAT3)by integrating LASSO and Cox regression analyses.Stratifying patients based on median risk scores,we demonstrate that high-risk patients exhibit significantly worse clinical outcomes across the TCGA cohort and five independent GEO datasets.Furthermore,this panel outperforms 136 previously published models in terms of predictive accuracy for 1-,3-,and 5-year survival rates.Validation multiplex immunofluorescence using an in-house tissue microarray cohort confirms that the 6-LRG signature serves as an independent prognostic factor.Additionally,high-risk patients exhibit distinct immunosuppressive tumor microenvironment and aggressive malignancy characteristics.Functional depletion of DPP7 significantly inhibits tumor cell proliferation,migration,and metastasis in both in vitro and in vivo settings.Moreover,DPP7 silencing attenuates epithelialemesenchymal transition,as evidenced by the upregulation of E-cadherin and downregulation of N-cadherin,Vimentin,and Snail.In conclusion,this study establishes an LRG-based model for COAD prognostic prediction and nominates DPP7 as a promising therapeutic target for COAD treatment.
基金Science and Technology Research Key Competitive Project of Quzhou Science and Technology Bureau(Nos.2023K266,2024K010)General Project for Cultivating Outstanding Young Teachers in Anhui Province’s Universities(2025).
文摘To address the limitations of traditional finite element methods,particularly the continuum assumption and difficulties in tracking the solid-liquid interface,this study introduces a lattice Boltzmann-based mathematical and physical model to simulate flow and heat transfer in the laser welding molten pool of tin-coated copper used in solar panel busbars(a thin strip or wire of conductive metal embedded on the surface of a solar cell to collect and conduct the electricity generated by the photovoltaic cell).The model incorporates key external forces,including surface tension,solid-liquid interface tension,and recoil pressure.A moving and rotating Gaussian-body heat source is adopted,with temperature treated as an implicit function of enthalpy.Coupled iterative schemes for the temperature and velocity fields are constructed using a dual-distribution function approach with a D3Q15 lattice structure.The model is implemented in Python,utilizing libraries such as NumPy,SciPy,Mayavi,and Matplotlib for computation and visualization.Simulation results reveal that the heat transfer mechanism in the molten pool transitions from pure conduction to conduction-convection due to surface tension effects,leading to the formation of multiple counter-rotating vortex structures.The peak temperature at the pool center reaches 3200 K,with maximum melt depth and width measured at 0.5 and 1.2 mm,respectively.Over time,both penetration depth and melt width increase,though the width exhibits a more pronounced growth.Comparison with experimental thermal cycling data from laser weld joints shows strong agreement,with a maximum error of less than 1%,validating the accuracy of the proposed method.
基金the National Key Research and Development Program of China(No.2021YFB3400100)the National Natural Science Foundation of China(Nos.52235003&U2241261)。
文摘This study introduces a novel approach for coupled aeroelastic analysis of panel subjected to supersonic airflow,utilizing Add-On Acoustic Black Hole(AABH)to mitigate panel flutter.Employing Galerkin's method to discretize aeroelastic equation of panel and leveraging finite element method to derive a reduced discrete model of AABH,this study effectively couples two substructures via interface displacement.Investigation into the interactive force highlights the modal effective mass,frequency discrepancy between oscillation and AABH mode,and modal damping ratio as critical factors influencing individual AABH mode in flutter suppression.The selection of effective AABH modes,closely linked to these factors,directly influences the accuracy of simulations.The results reveal that AABH notably enhances the panel's critical flutter boundary by14.6%,a significant improvement over the 3.6%increase afforded by equivalent mass.Furthermore,AABH outperforms both the tuned mass damper and nonlinear energy sink in flutter suppression efficacy.By adjusting the AABH's geometrical parameters to increase the accumulative modal effective mass within the pertinent frequency range,or choosing a suitable installation position for AABH,its performance in flutter suppression is further optimized.These findings not only underscore the AABH's potential in enhancing aeroelastic stability but also provide a foundation for its optimal design.
基金Project(2022A02480004)supported by the Major Project of China Railway Design CorporationProject(2023RC1011)supported by the Science and Technology Innovation Program of Hunan Province,China+2 种基金Project(2024JJ6515)supported by the Hunan Provincial Natural Science Foundation,ChinaProject(kq2402220)supported by the Natural Science Foundation of Changsha City,ChinaProject(52402438)supported by the National Natural Science Foundation of China。
文摘To enhance the resistance of honeycomb sandwich panel against local impact,this study delved into the matching relationship between face sheets and core.An integrated approach,combining experiment,simulation,and theoretical methods,was used.Local loading experiments were conducted to validate the accuracy of the finite element model.Furthermore,a control equation was formulated to correlate structural parameters with response modes,and a matching coefficientλ(representing the ratio of core thickness to face sheet thickness)was introduced to establish a link between these parameters and impact characteristics.A demand-driven reverse design methodology for structural parameters was developed,with numerical simulations employed to assess its effectiveness.The results indicate that the proposed theory can accurately predict response modes and key indicators.An increase in theλbolsters the structural indentation resistance while concurrently heightens the likelihood of penetration.Conversely,a decrease in theλimproves the resistance to penetration,albeit potentially leading to significant deformations in the rear face sheet.Numerical simulations demonstrate that the reverse design methodology significantly enhances the structural penetration resistance.Comparative analyses indicate that appropriate matching reduces indentation depth by 27.4% and indentation radius by 41.8%of the proposed structure.
基金The authors express their gratitude to Universiti Pura Malaysia(UPM),Malaysia for granting Putra IPS vote number 9742900.
文摘The increasing demand to decrease manufacturing costs and weight reduction is driving the aircraft industry to change the use of conventional riveted stiffened panels to integral stiffened panels(ISP)for aircraft fuselage structures.ISP is a relatively new structure in aircraft industries and is considered the most significant development in a decade.These structures have the potential to replace the conventional stiffened panel due to the emergence of manufacturing technology,including welding,high-speed machining(HSM),extruding,and bonding.Although laser beam welding(LBW)and friction stir welding(FSW)have been applied in aircraft companies,many investigations into ISP continue to be conducted.In this review article,the current state of understanding and advancement of ISP structure is addressed.A particular explanation has been given to(a)buckling performance,(b)fatigue performance of the ISP,(c)modeling and simulation aspects,and(d)the impact of manufacturing decisions in welding processes on the final structural behavior of the ISP during service.Compared to riveted panels,machined ISP had a better compressive buckling load,and FSW integral panels had a lower buckling load than riveted panels.Compressive residual stress decreased the stress intensity factor(SIF)rates,slowing down the growth of fatigue cracks as occurred in FSW and LBW ISP.
文摘Wind tunnel experiment and CFD(computational fluid dynamics)simulation with LES(large eddy simulation)have been conducted to investigate the characteristics of peak wind force coefficients of porous panels mounted on the roofs of high-rise buildings.First,aerodynamic modelling of porous panels was discussed.The relation between pressure loss coefficient and porosity was obtained.Then,a wind tunnel experiment was conducted to measure the wind forces(net wind pressures)acting on solid and porous panels mounted on the roof of a high-rise building.Because it was difficult to measure the pressures on both sides of thin,porous panel at the same location simultaneously,we proposed to use the roof edge pressures near the panel for the panel’s inside-surface pressures.This experimental method was validated by a CFD simulation reproducing the wind tunnel experiment.The characteristics of peak wind force coefficients of porous panels mounted on the roofs of high-rise buildings were made clear.Finally,positive and negative peak wind force coefficients for designing the rooftop porous panels were proposed.
基金funded by the Deanship of Scientific Research and Libraries,Princess Nourah bint Abdulrahman University,through the Program of Research Project Funding after Publication,grant No.(RPFAP-88-1445).
文摘Cooling system design applicable to more than one photovoltaic(PV)unit may be challenging due to the arrangement and geometry of the modules.Different cooling techniques are provided in this study to regulate the temperature of conductive panels that are arranged perpendicular to each other.The model uses two vented cavity systems and one L-shaped channel with ternary nanofluid enhanced non-uniform magnetic field.Their cooling performances and comparative results between different systems are provided.The finite element method is used to conduct a numerical analysis for a range of values of the following:the strength of themagnetic field(Hartmann number(Ha)between 0 and 50),the inclination of the magnetic field(γbetween 0 and 90),and the loading of nanoparticles in the base fluid(ϕbetween 0 and 0.03),taking into account both uniformand non-uniformmagnetic fields.For the L-shaped channel and vented cavities,vortex size is controlled by imposing magnetic field and adjusting its strength.Whether uniform or non-uniform magnetic field is applied affects the cooling performances for different cooling configurations.Temperature drops of the horizontal panel with different magnetic field strengths by using channel cooling,vented cavity-1 and vented cavity-2 systems for uniformmagnetic are 11℃,21.5℃,and 3℃when the reference case of Ha=0 is considered for the same cooling systems.However,they become 9.5℃,13.5℃,and 12.5℃when nonuniform magnetic field is used.In the presence of uniform magnetic field effects and changing its magnitude,the use of cooling channel in vented cavity-1 and vented cavity-2 systems results in temperature drops of 4℃,10.8℃,and 3.8℃for vertical panels.On the other hand,when non-uniform magnetic field effects are present,they become 0.5℃,2.1℃,and 9℃.For L-channel cooling,the average Nu for the horizontal panel is more affected byγ,andNu rises asγrises.With increasing nanoparticle loading of ternary nanofluid,the average panel surface temperature shows a linear drop.For the horizontal panel,the temperature declines for nanofluid at the highest loading are 4℃,10℃,and 12℃as compared to using only base fluid.The values of 5℃,7℃,and 11℃are obtained for the vertical panel.Different cooling systems’performance is estimated using artificial neural networks.The method captures the combined impact of applying non-uniformmagnetic field and nanofluid together on the cooling performancewhile accounting for varied cooling strategies for both panels.
