A new statistical method, the fuzzy analytical method, was introduced in the optimization processes of liposome preparation. It took the full advantage of the information from orthogonal experiments to obtain the opti...A new statistical method, the fuzzy analytical method, was introduced in the optimization processes of liposome preparation. It took the full advantage of the information from orthogonal experiments to obtain the optimal liposome preparation conditions by considering all the evaluation indexes. Liposomes were made by the modified reverse-phase evaporation method and the properties of liposomes including size, encapsulation efficiency and physical stability were selected as the evaluation indexes to indicate the quality of liposomes. The experimental data of these properties were analyzed by three different methods including direct observation, variance analysis and fuzzy analytical method. The optimal preparation conditions obtained from these methods were validated with further experiments. The results of all possible combinations of levels for all factors in orthogonal experiments were acquired by the fuzzy analytical method. All evaluation indexes were taken into account and the optimal preparation condition was obtained. The optimal preparation conditions from direct observation and fuzzy analytical method were different and further validation studies indicated that the optimal conditions obtained from the fuzzy analytical method were in agreement with that from traditional statistical analysis. Fuzzy analytical method avoided the problem resulted from the traditional method, in which different levels of the same factor were obtained when considering different evaluation indexes. More information could be obtained from the fuzzy analytical method and the blind area within the experimental range was eliminated. As a result, fuzzy analytical method can be applied in the optimization processes of liposome preparation.展开更多
Aim New statistical method was applied in data analysis of orthogonal experiments to optimize the preparation of liposome. Method Particle size, zeta potential, encapsulation efficiency and physical stability of lipos...Aim New statistical method was applied in data analysis of orthogonal experiments to optimize the preparation of liposome. Method Particle size, zeta potential, encapsulation efficiency and physical stability of liposomes were selected by orthogonal design as evaluating indicators. Through three statistical methods （direct observation, variance analysis and stepwise multiple regression）, the optimized preparing conditions were acquired and validated by experiment. Results All of the four indicators were different by these analyses. The validation experiments indicated that the optimized conditions by stepwise multiple regressions were better than that by traditional analysis. Conclusion Experiment results suggested that multiple regressions could avoid the weakness of direct observation and variance analysis, but more work should be done in preparing liposomes.展开更多
To recycle residual iron efficiently in Bayer red mud, three-factor three-level orthogonal experiments on carbon-bearing pellets of Bayer red mud were conducted on the basis of their characteristics. The influences of...To recycle residual iron efficiently in Bayer red mud, three-factor three-level orthogonal experiments on carbon-bearing pellets of Bayer red mud were conducted on the basis of their characteristics. The influences of CaO dosage, temperature and roast- ing time on total iron content and iron recovery of reduced iron powder were studied. Results showed that these factors slightly influenced iron recovery, but significantly influenced total iron content. The principal factor influencing total iron content was CaO dosage, followed by temperature and roasting time. An increase in CaO dosage could decrease total iron content, whereas an increase in temperature and an extension of roasting time could improve total iron content. The reduced iron powder with total iron content of 88.4 l% and iron recovery rate of 97.97% can be obtained under the optimal conditions of temperature of 1 275 ℃, roasting time of 60 min and CaO dosage of 7.5%. The X-ray diffraction （XRD） and scanning electron microscopy （SEM） analyses of the reduced pellets showed that iron minerals in red mud were almost completely reduced to metallic iron. The principal factor influencing the total iron content of reduced iron powder was the grain size of metallic iron particles. An increase in CaO dosage hindered the growth of metallic iron particles, whereas an increase in temperature and an extension of roasting time could neutralise the effect of CaO dosage. Therefore, CaO dosage should be decreased when iron minerals in red mud can be adequately reduced into metallic iron.展开更多
Biological aerated filters have many advantages such as small volume and high treatment efficiency. This research focused on sewage treatment performance of integrated biological aerated filter (IBAF) under different ...Biological aerated filters have many advantages such as small volume and high treatment efficiency. This research focused on sewage treatment performance of integrated biological aerated filter (IBAF) under different conditions such as aeration, hydraulic retention time and the height of fillers layer, to identify the turn of marked affecting factor of removal performance through orthogonal experiments, optimize the function parameter of IBAF, reveal the regularity of sewage treatment of IBAF under different conditions, and adopt suitable measures to guarantee excess water quality of IBAF.展开更多
Orthogonal method was adopted to optimize the preozonation process and to minimize the bromate formation. Factors such as contact time, pH and ammonia concentration were investigated by orthogonal experiments to under...Orthogonal method was adopted to optimize the preozonation process and to minimize the bromate formation. Factors such as contact time, pH and ammonia concentration were investigated by orthogonal experiments to understand the interaction of various operation conditions on the formation of bromate and other disinfection byproducts(DBPs). Results showed that pH had the most significant influence on the minimization of bromate formation. The factors influencing the formation of bromate were in order of pH > contact time > ammonia concentration. For the formation of trihalomethanes(THMs) and haloacetic acids(HAAs), however, contact time significantly influenced their formation potential. In the practical preozonation process of waterworks, it is appropriate to set preozonation contact time to be 20 min. In order to minimize the formation of bromate, pH value of the raw water should be adjusted to 6. 0, and a certain concentration of ammonia could be added into the water to strengthen the minimization effect when the concentration of bromide in the raw water is higher than that in the experimental water.展开更多
To investigate the influence of W and Al on the microstructure and mechanical properties of a high-W superalloy,the Thermo-Calc calculation was utilized to simulate the microstructure with various W and Al contents.Th...To investigate the influence of W and Al on the microstructure and mechanical properties of a high-W superalloy,the Thermo-Calc calculation was utilized to simulate the microstructure with various W and Al contents.The results indicated that the concentration of W and Al exceeded 15.7 wt%and 5.9 wt%,respectively,the abnormal tungsten-richα-W phase would precipitate.Compared with the results of orthogonal experiment,the precipitation ofα-W phase is consistent with thermodynamic calculation results.The presence of Al not only influenced the precipitation ofα-W phase but also impacted the eutectic content and theγʹ-size,both of which showed an increase with higher Al concentrations.Excessive W and Al contents promoted the precipitation ofα-W phase,escalating the site of crack nucleation,and ultimately decreasing the plasticity.In the process of creep deformation(975℃/235 MPa),the raftedγ'phases were more continuous with increasing W contents,which increased the difficulty of dislocation climbing.As Al content increased,the density of interfacial dislocation network increased.The dislocations were entangled with each other,and the hindrance of dislocation movement was enhanced,which improved the stress rupture life.However,the precipitation of the hard and brittleα-W phase was attributed to the excessive W and Al,which increased the tendency of crack formation and significantly diminished the stress rupture life.The alloy exhibited the highest stress rupture life of 110.46 h when the W and Al contents were 15.7 wt%and 5.9 wt%,respectively.展开更多
[Objective] This study aimed to explore optimum conditions for papain-as- sisted extraction of polysaccharides from Agrocybe aegirit. [Method] Because enzyme is capable of destroying organizational structure of cells,...[Objective] This study aimed to explore optimum conditions for papain-as- sisted extraction of polysaccharides from Agrocybe aegirit. [Method] Because enzyme is capable of destroying organizational structure of cells, papain was selected to cat- alyze cells to let polysaccharides out. An orthogonal experiment was carried out to investigate the effects of hydrolysis temperature, hydrolysis time, enzyme concentra- tion and solid to liquid ratio on extraction of polysaccharides from A. aegirit. [Result] Through the orthogonal experiment, the optimum papain-assisted extraction conditions were obtained： hydrolysis temperature, 45 ℃; hydrolysis time, 2 h; enzyme concen- tration 2%; solid to liquid ratio, 1：80. [Conclusion] This study will provide a reference for extraction of polysaccharides from A. aegirit.展开更多
As the fundamental unit of soil,aggregates exhibit significant variations in their abilities to adsorb and desorb trace elements,depending on their size.Batch experiments were conducted to investigate the characterist...As the fundamental unit of soil,aggregates exhibit significant variations in their abilities to adsorb and desorb trace elements,depending on their size.Batch experiments were conducted to investigate the characteristics of adsorption and desorption of cadmium(Cd),copper(Cu),and lead(Pb)on and from soil aggregate fractions from three layers of a calcareous soil profile in Changxing County,Zhejiang Prvince,China.The results showed that both Langmuir and Freundlich models successfully described the isothermal adsorption processes of single Cd,Cu,and Pb on different soil aggregates.Additionally,aggregates from the bottom soil layer showed the highest maximum adsorption capacity and required the lowest energy for Cd,Cu,and Pb adsorption compared to aggregates from upper soil layers.The physicochemical properties of soil aggregates were found to govern the adsorption and desorption processes of heavy metals rather than the aggregate size,wherein the contents of iron/aluminum oxides and organic matter were the most crucial influencing factors.Cadmium displayed higher mobility than Cu and Pb in different soil aggregates,and the maximum adsorption capacities of the metal ions followed the order of Pb>Cu>Cd,while their desorption rates followed the order of Cd>Cu>Pb.Additionally,the<0.053 mm microaggregates presented the lowest desorption rates for Cd,Cu,and Pb compared to other soil aggregate fractions in each soil layer.Furthermore,the orthogonal experiment results demonstrated that the competitive adsorption between metals occurred on soil aggregates in the ternary heavy metal system,but only the desorption of Pb was significantly affected by the coexistence of Cd and Cu.展开更多
Silicon Carbide (SiC) wafers have been widely used in micro- and nano-devices due to their excellent optical and material properties. However, polishing SiC wafers has been challenging and inefficient, tending to caus...Silicon Carbide (SiC) wafers have been widely used in micro- and nano-devices due to their excellent optical and material properties. However, polishing SiC wafers has been challenging and inefficient, tending to cause significant surface crack and subsurface damage. This work proposed modifying SiC surface properties by ion implantation to improve machining efficiency, suppress surface crack, and reduce damage. High-energy ion implantation disrupted the SiC crystal lattice, reducing hardness and elastic modulus while increasing brittle-ductile transition depth, thus changing the removal mode from brittle fracture to plastic removal. Theoretical models of material removal rate and surface roughness were established for abrasive polishing of the SiC wafers. Polishing experiments were conducted on ion-implanted, modified SiC samples. The improvement mechanisms of ion implantation on surface damage, removal rate, morphology, and residual stress were investigated. The effect of ion implantation on the polished surface quality of SiC was investigated through orthogonal experiments. The results showed that ion implantation can significantly improve the average material removal rate of the SiC samples. Additionally, the ion-implanted samples had exhibited remarkable reductions in surface roughness, surface damage, and tensile residual stress.展开更多
Hydraulic sandblasting perforation plays a crucial role in the fracturing and reconstruction of unconventional oil and gas reservoirs.The jet nozzle is an essential part of the hydraulic perforation tool.Insufficient ...Hydraulic sandblasting perforation plays a crucial role in the fracturing and reconstruction of unconventional oil and gas reservoirs.The jet nozzle is an essential part of the hydraulic perforation tool.Insufficient penetration depth,caused by excessive jet distances,presents challenges during the perforation process.To overcome this,an optimization design of the nozzle structure is required to enhance the perforation efficiency.In this paper,a computational fluid-dynamic model for conical-cylindrical nozzles has been elaborated.To further improve the rock-breaking efficiency of the jet nozzle,a fillet design is introduced at the nozzle inlet section.The SST k-ωmodel is employed to account for turbulent flow effects in submerged conditions.The results indicate that the nozzle’s geometric parameters greatly influence the flow characteristics.The orthogonal experimental method is employed to optimize the flow channel structure of the nozzle,taking the length of constant velocity core as the evaluation index.The following optimized geometric parameters for the conical-cylindrical nozzle have been determined accordingly:a cylindrical segment diameter of 3.2 mm,a contraction angle of 12°,a contraction segment length of 8 mm,a cylindrical segment length of 6.4 mm,and a fillet radius of 2 mm.展开更多
This study aims to explore the potential of using a blended pulp from Mikania micrantha(M.micrantha)and waste paper for producing composite paper.The effects of the mass ratio of M.micrantha stem to waste paper(MRMW),...This study aims to explore the potential of using a blended pulp from Mikania micrantha(M.micrantha)and waste paper for producing composite paper.The effects of the mass ratio of M.micrantha stem to waste paper(MRMW),the beating time(BT),the water-to-pulp mass ratio(WPMR)and the times of pulp suspension screening(TPSS)on the paper’s basic structural,optical and mechanical properties are investigated.It is found that MRMW primarily affects the grammage(mass per unit area),density,bulkness and whiteness;WPMR mainly affects the thickness and density;TPSS mainly affects the thickness and grammage.When MRMW is 3:7,the composite paper shows higher values for thickness,grammage,density and whiteness;whereas when MRMW is 7:3,these values are lower.Extending BT can increase paper density.The tensile strengths of all prepared samples fall in the range of 1.5 to 4.1 kN/m,indicating their excellent strength properties that meet the demands of many paper applications.The artistic bags and lampshades crafted from this composite paper exhibit a more natural texture compared to conventional packaging paper.This research demonstrates the feasibility of papermaking by using M.micrantha,while showcasing the potential for synergistic integration of waste resources with traditional hand papermaking techniques.展开更多
[Objectives] To optimize the extraction process of Damp-clearing Mixture and establish the quality control indicators. [Methods] The extraction process of Coicis Semen Damp-clearing Mixture was optimized by L 9(3 4) o...[Objectives] To optimize the extraction process of Damp-clearing Mixture and establish the quality control indicators. [Methods] The extraction process of Coicis Semen Damp-clearing Mixture was optimized by L 9(3 4) orthogonal design with the content of total flavonoids and the dry yield rate as the evaluation indicators, and the amount of water, extraction time and extraction times as the factors, to determine the formation process of Coicis Semen Damp-clearing Mixture. In addition, the quality of the mixture was studied by thin layer chromatography (TLC). [Results] The optimal extraction process of Coicis Semen Damp-clearing Mixture was as follows: decocting twice, one hour each time, adding 8 times of water in the first time and 6 times of water in the second time, standing the extract in a cool place, adding 0.1% steviosin to facilitate the formation of the mixture;Acori Tatarinowii Rhizoma and Dendrophenol in the mixture were well separated by TLC with good reproducibility and specificity. [Conclusions] The preparation process and quality control indicators determined by the experiment are reasonable and feasible. It can provide a reference for the pilot production and quality standards of Coicis Semen Damp-clearing Mixture.展开更多
In order to analyze the influence of configuration parameters on dynamic characteristics of machine tools in the working space, the configuration parameters have been suggested based on the orthogonal experiment metho...In order to analyze the influence of configuration parameters on dynamic characteristics of machine tools in the working space, the configuration parameters have been suggested based on the orthogonal experiment method. Dynamic analysis of a milling machine, which is newly designed for producing turbine blades, has been conducted by utilizing the modal synthesis method. The finite element model is verified and updated by experimental modal analysis （EMA） of the machine tool. The result gained by modal synthesis method is compared with whole-model finite element method （FEM） result as well. According to the orthogonal experiment method, four configuration parameters of machine tool are considered as four factors for dynamic characteristics. The influence of configuration parameters on the first three natural frequencies is obtained by range analysis. It is pointed out that configuration parameter is the most important factor affecting the fundamental frequency of machine tools, and configuration parameter has less effect on lower-order modes of the system than others. The combination of configuration parameters which makes the fundamental frequency reach the maximum value is provided. Through demonstration, the conclusion can be drawn that the influence of configuration parameters on the natural frequencies of machine tools can be analyzed explicitly by the orthogonal experiment method, which offers a new method for estimating the dynamic characteristics of machine tools.展开更多
Objective It is imperative to provide some consistent experimental results for the extraction of flavonid from Fructus Gardeniae. Methods The key extraction parameters that influenced the yield of flavonid from Fructu...Objective It is imperative to provide some consistent experimental results for the extraction of flavonid from Fructus Gardeniae. Methods The key extraction parameters that influenced the yield of flavonid from Fructus Gardeniae were optimized by employing an orthogonal experiment [L9（3）4], including the ratio of buffer solution （Na2B4O7· 10H2O） to raw material, concentration of Fructus Gardeniae in extracting solution, extraction time and pH of buffer solution. An UV/Vis detector was used to perform the qualitative and quantitative analyses of the extracted flavonid with the using of the standard sample. Results The maximum extraction yield of the crude extract was 5.0533 （mg/g） after 20 min when the mass ratio of Na2B4O7 · 10H2O to raw material was 0.4%, the concentration of Fructus Gardeniae in the extraction solution was 1/12 （g/mL）, and pH of buffer solution was 4.5. The positive reactions to the Molish and HCI-Mg tests suggested that the extracted compound was flavonoid, and FTIR measurements also identified the presence of flavonoid in the extracts. Conclusion This work is expected to provide a basis for further research, development, and utilization of Fructus gardenia in flavonid extraction.展开更多
An integer linear bilevel programming problem is firstly transformed into a binary linear bilevel programming problem, and then converted into a single-level binary implicit programming. An orthogonal genetic algorith...An integer linear bilevel programming problem is firstly transformed into a binary linear bilevel programming problem, and then converted into a single-level binary implicit programming. An orthogonal genetic algorithm is developed for solving the binary linear implicit programming problem based on the orthogonal design. The orthogonal design with the factor analysis, an experimental design method is applied to the genetic algorithm to make the algorithm more robust, statistical y sound and quickly convergent. A crossover operator formed by the orthogonal array and the factor analysis is presented. First, this crossover operator can generate a smal but representative sample of points as offspring. After al of the better genes of these offspring are selected, a best combination among these offspring is then generated. The simulation results show the effectiveness of the proposed algorithm.展开更多
The optimization design of the power system is essential for stratospheric airships with paradoxical requirements of high reliability and low weight. The methodology of orthogonal experiment is presented to deal with ...The optimization design of the power system is essential for stratospheric airships with paradoxical requirements of high reliability and low weight. The methodology of orthogonal experiment is presented to deal with the problem of the optimization design of the airship's power system. Mathematical models of the solar array, regenerative fuel cell, and power management subsystem (PMS) are presented. The basic theory of the method of orthogonal experiment is discussed, and the selection of factors and levels of the experiment and the choice of the evaluation function are also revealed. The proposed methodology is validated in the optimization design of the power system of the ZhiYuan-2 stratospheric airship. Results show that the optimal configuration is easily obtained through this methodology. Furthermore, the optimal configuration and three sub-optimal configurations are in the Pareto frontier of the design space. Sensitivity analyses for the weight and reliability of the airship's power system are presented.展开更多
This paper studies the excavation collapse at the Xianghu subway station on Hangzhou metro line 1.The objective is to present an overview of this case study and discuss the cause of the failure.Through field investiga...This paper studies the excavation collapse at the Xianghu subway station on Hangzhou metro line 1.The objective is to present an overview of this case study and discuss the cause of the failure.Through field investigation and preliminary analysis,the reasons for the excavation collapse were the misuse of the soil parameters,over excavation,incorrect installation of steel struts,invalid monitoring data,and inadequate ground improvement.Finally,a small strain constitutive model was used for further analysis.In order to estimate damage efficiently,the orthogonal array(OA) was introduced for screening the key factor in the numerical experiments.Six estimated indexes including deformations and internal forces of the excavation were taken,and the effectiveness of four factors which may cause the collapse was evaluated.Through numerical experiments and interaction analysis,it is found that the deformation and internal force can be well controlled by jet grouting of the subsoil under the final cutting surface,but increasing the improvement ratio of the jet grouting cannot help optimize the excavation behavior efficiently,and without jet grouting and the fourth level struts,the deformation and internal force of the excavation in this case will far surpass the allowable value.展开更多
Cavitation is one of the most important performance of centrifugal pumps. However, the current optimization works of centrifugal pump are mostly focusing on hydraulic efficiency only, which may result in poor cavitati...Cavitation is one of the most important performance of centrifugal pumps. However, the current optimization works of centrifugal pump are mostly focusing on hydraulic efficiency only, which may result in poor cavitation performance. Therefore, it is necessary to find an appropriate solution to improve cavitation performance with acceptable efficiency. In this paper, to improve the cavitation performance of a centrifugal pump with a vaned diffuser, the influence of impeller geometric parameters on the cavitation of the pump is investigated using the orthogonal design of experiment （DOE） based on computational fluid dynamics. The impeller inlet diameter D1, inlet incidence angle Aft, and blade wrap angle ~0 are selected as the main impeller geometric parameters and the orthogonal experiment of L9（3＂3） is performed. Three-dimensional steady simulations for cavitation are conducted by using constant gas mass fraction model with second-order upwind, and the predicated cavitation performance is validated by laboratory experiment. The optimization results are obtained by the range analysis method to improve cavitation performance without obvious decreasing the efficiency of the centrifugal pump. The internal flow of the pump is analyzed in order to identify the flow behavior that can affect cavitation performance. The results show that D1 has the greatest influence on the pump cavitation and the final optimized impeller provides better flow distribution at blade leading edge. The final optimized impeller accomplishes better cavitation and hydraulic performance and the NPSHR decreases by 0.63m compared with the original one. The presented work supplies a feasible route in engineering practice to optimize a centrifugal pump impeller for better cavitation performance.展开更多
[Objectives] To screen the optimal extraction conditions of flavonoids from leaves of Paliurus ramosissimus( Lour.) Poir.,measure the content of flavonoids in leaves of P. ramosissimus. using the Microplate Reader,and...[Objectives] To screen the optimal extraction conditions of flavonoids from leaves of Paliurus ramosissimus( Lour.) Poir.,measure the content of flavonoids in leaves of P. ramosissimus. using the Microplate Reader,and provide experimental basis for the development of medicinal resources of P. ramosissimus. [Methods] The ultrasonic extraction method was adopted and orthogonal design was carried out to study the effects of ethanol concentration( A),ultrasonic time( B),the solid-to-liquid ratio( C) on the extraction of flavonoids from leaves of P. ramosissimus. The Microplate Reader was used to measure the content of flavonoids in leaves of P. ramosissimus. in different extraction conditions,P. ramosissimus. and the optimal extraction conditions were used to measure the content of flavonoids from leaves of P. ramosissimus.[Results]Effects of the ultrasonic extraction method on the extraction rate of flavonoids from leaves of P. ramosissimus: extraction times >ethanol concentration > Ultrasound time > solid-liquid ratio. The screened optimal extraction process was: ethanol concentration of 65%,the solid-to-liquid ratio of 1∶ 25,ultrasonic time of 2 h and extraction times Under this condition,the extraction rate of total flavonoids in leaves of P. ramosissimus. was 2. 56%. [Conclusions] This method is simple and feasibility,reliable,and suitable for rapid measurement with large samples.展开更多
文摘A new statistical method, the fuzzy analytical method, was introduced in the optimization processes of liposome preparation. It took the full advantage of the information from orthogonal experiments to obtain the optimal liposome preparation conditions by considering all the evaluation indexes. Liposomes were made by the modified reverse-phase evaporation method and the properties of liposomes including size, encapsulation efficiency and physical stability were selected as the evaluation indexes to indicate the quality of liposomes. The experimental data of these properties were analyzed by three different methods including direct observation, variance analysis and fuzzy analytical method. The optimal preparation conditions obtained from these methods were validated with further experiments. The results of all possible combinations of levels for all factors in orthogonal experiments were acquired by the fuzzy analytical method. All evaluation indexes were taken into account and the optimal preparation condition was obtained. The optimal preparation conditions from direct observation and fuzzy analytical method were different and further validation studies indicated that the optimal conditions obtained from the fuzzy analytical method were in agreement with that from traditional statistical analysis. Fuzzy analytical method avoided the problem resulted from the traditional method, in which different levels of the same factor were obtained when considering different evaluation indexes. More information could be obtained from the fuzzy analytical method and the blind area within the experimental range was eliminated. As a result, fuzzy analytical method can be applied in the optimization processes of liposome preparation.
文摘Aim New statistical method was applied in data analysis of orthogonal experiments to optimize the preparation of liposome. Method Particle size, zeta potential, encapsulation efficiency and physical stability of liposomes were selected by orthogonal design as evaluating indicators. Through three statistical methods （direct observation, variance analysis and stepwise multiple regression）, the optimized preparing conditions were acquired and validated by experiment. Results All of the four indicators were different by these analyses. The validation experiments indicated that the optimized conditions by stepwise multiple regressions were better than that by traditional analysis. Conclusion Experiment results suggested that multiple regressions could avoid the weakness of direct observation and variance analysis, but more work should be done in preparing liposomes.
基金Sponsored by National High Technology Research and Development Program of China(2012AA06A109)
文摘To recycle residual iron efficiently in Bayer red mud, three-factor three-level orthogonal experiments on carbon-bearing pellets of Bayer red mud were conducted on the basis of their characteristics. The influences of CaO dosage, temperature and roast- ing time on total iron content and iron recovery of reduced iron powder were studied. Results showed that these factors slightly influenced iron recovery, but significantly influenced total iron content. The principal factor influencing total iron content was CaO dosage, followed by temperature and roasting time. An increase in CaO dosage could decrease total iron content, whereas an increase in temperature and an extension of roasting time could improve total iron content. The reduced iron powder with total iron content of 88.4 l% and iron recovery rate of 97.97% can be obtained under the optimal conditions of temperature of 1 275 ℃, roasting time of 60 min and CaO dosage of 7.5%. The X-ray diffraction （XRD） and scanning electron microscopy （SEM） analyses of the reduced pellets showed that iron minerals in red mud were almost completely reduced to metallic iron. The principal factor influencing the total iron content of reduced iron powder was the grain size of metallic iron particles. An increase in CaO dosage hindered the growth of metallic iron particles, whereas an increase in temperature and an extension of roasting time could neutralise the effect of CaO dosage. Therefore, CaO dosage should be decreased when iron minerals in red mud can be adequately reduced into metallic iron.
文摘Biological aerated filters have many advantages such as small volume and high treatment efficiency. This research focused on sewage treatment performance of integrated biological aerated filter (IBAF) under different conditions such as aeration, hydraulic retention time and the height of fillers layer, to identify the turn of marked affecting factor of removal performance through orthogonal experiments, optimize the function parameter of IBAF, reveal the regularity of sewage treatment of IBAF under different conditions, and adopt suitable measures to guarantee excess water quality of IBAF.
基金Supported by the National Natural Science Foundation of China(No.51008162)Natural Science Foundation of Tianjin(No.10JCYBJC03500)
文摘Orthogonal method was adopted to optimize the preozonation process and to minimize the bromate formation. Factors such as contact time, pH and ammonia concentration were investigated by orthogonal experiments to understand the interaction of various operation conditions on the formation of bromate and other disinfection byproducts(DBPs). Results showed that pH had the most significant influence on the minimization of bromate formation. The factors influencing the formation of bromate were in order of pH > contact time > ammonia concentration. For the formation of trihalomethanes(THMs) and haloacetic acids(HAAs), however, contact time significantly influenced their formation potential. In the practical preozonation process of waterworks, it is appropriate to set preozonation contact time to be 20 min. In order to minimize the formation of bromate, pH value of the raw water should be adjusted to 6. 0, and a certain concentration of ammonia could be added into the water to strengthen the minimization effect when the concentration of bromide in the raw water is higher than that in the experimental water.
基金financial support received from the National Key Research and Development Program of China(2022YFB3705000)the National Natural Science Foundation of China(No.52303394)the Liaoning Provincial Natural Science Foundation(No.2023-BS-015).
文摘To investigate the influence of W and Al on the microstructure and mechanical properties of a high-W superalloy,the Thermo-Calc calculation was utilized to simulate the microstructure with various W and Al contents.The results indicated that the concentration of W and Al exceeded 15.7 wt%and 5.9 wt%,respectively,the abnormal tungsten-richα-W phase would precipitate.Compared with the results of orthogonal experiment,the precipitation ofα-W phase is consistent with thermodynamic calculation results.The presence of Al not only influenced the precipitation ofα-W phase but also impacted the eutectic content and theγʹ-size,both of which showed an increase with higher Al concentrations.Excessive W and Al contents promoted the precipitation ofα-W phase,escalating the site of crack nucleation,and ultimately decreasing the plasticity.In the process of creep deformation(975℃/235 MPa),the raftedγ'phases were more continuous with increasing W contents,which increased the difficulty of dislocation climbing.As Al content increased,the density of interfacial dislocation network increased.The dislocations were entangled with each other,and the hindrance of dislocation movement was enhanced,which improved the stress rupture life.However,the precipitation of the hard and brittleα-W phase was attributed to the excessive W and Al,which increased the tendency of crack formation and significantly diminished the stress rupture life.The alloy exhibited the highest stress rupture life of 110.46 h when the W and Al contents were 15.7 wt%and 5.9 wt%,respectively.
基金Supported by Youth Fund of National Natural Science Foundation of China(31201242/C130405)Science Research Program of Education Department of Hubei Province(Q20143004)~~
文摘[Objective] This study aimed to explore optimum conditions for papain-as- sisted extraction of polysaccharides from Agrocybe aegirit. [Method] Because enzyme is capable of destroying organizational structure of cells, papain was selected to cat- alyze cells to let polysaccharides out. An orthogonal experiment was carried out to investigate the effects of hydrolysis temperature, hydrolysis time, enzyme concentra- tion and solid to liquid ratio on extraction of polysaccharides from A. aegirit. [Result] Through the orthogonal experiment, the optimum papain-assisted extraction conditions were obtained： hydrolysis temperature, 45 ℃; hydrolysis time, 2 h; enzyme concen- tration 2%; solid to liquid ratio, 1：80. [Conclusion] This study will provide a reference for extraction of polysaccharides from A. aegirit.
基金financially supported by the National Key Research and Development Program of China(No.2017YFD0800305)。
文摘As the fundamental unit of soil,aggregates exhibit significant variations in their abilities to adsorb and desorb trace elements,depending on their size.Batch experiments were conducted to investigate the characteristics of adsorption and desorption of cadmium(Cd),copper(Cu),and lead(Pb)on and from soil aggregate fractions from three layers of a calcareous soil profile in Changxing County,Zhejiang Prvince,China.The results showed that both Langmuir and Freundlich models successfully described the isothermal adsorption processes of single Cd,Cu,and Pb on different soil aggregates.Additionally,aggregates from the bottom soil layer showed the highest maximum adsorption capacity and required the lowest energy for Cd,Cu,and Pb adsorption compared to aggregates from upper soil layers.The physicochemical properties of soil aggregates were found to govern the adsorption and desorption processes of heavy metals rather than the aggregate size,wherein the contents of iron/aluminum oxides and organic matter were the most crucial influencing factors.Cadmium displayed higher mobility than Cu and Pb in different soil aggregates,and the maximum adsorption capacities of the metal ions followed the order of Pb>Cu>Cd,while their desorption rates followed the order of Cd>Cu>Pb.Additionally,the<0.053 mm microaggregates presented the lowest desorption rates for Cd,Cu,and Pb compared to other soil aggregate fractions in each soil layer.Furthermore,the orthogonal experiment results demonstrated that the competitive adsorption between metals occurred on soil aggregates in the ternary heavy metal system,but only the desorption of Pb was significantly affected by the coexistence of Cd and Cu.
基金support from the China Postdoctoral Science Foundation(No.2023M742735)the Postdoctoral Fellowship Program of CPSF,China(No.GZC20232029)+5 种基金the National Natural Science Foundation of China(No.52475530)the Shaanxi Postdoctoral Science Foundation,China(No.2023BSHEDZZ175)the Innovation Capability Support Program of Shaanxi Province,China(No.2021TD-23)the Key Industrial Chain Core Technology Research Project in Xi’an,China(No.23LLRH0029)the Natural Science Basic Research Program of Shaanxi,China(No.2024JC-YBQN-0490)the Fundamental Research Funds for the Central Universities,China(No.ZYTS24023).
文摘Silicon Carbide (SiC) wafers have been widely used in micro- and nano-devices due to their excellent optical and material properties. However, polishing SiC wafers has been challenging and inefficient, tending to cause significant surface crack and subsurface damage. This work proposed modifying SiC surface properties by ion implantation to improve machining efficiency, suppress surface crack, and reduce damage. High-energy ion implantation disrupted the SiC crystal lattice, reducing hardness and elastic modulus while increasing brittle-ductile transition depth, thus changing the removal mode from brittle fracture to plastic removal. Theoretical models of material removal rate and surface roughness were established for abrasive polishing of the SiC wafers. Polishing experiments were conducted on ion-implanted, modified SiC samples. The improvement mechanisms of ion implantation on surface damage, removal rate, morphology, and residual stress were investigated. The effect of ion implantation on the polished surface quality of SiC was investigated through orthogonal experiments. The results showed that ion implantation can significantly improve the average material removal rate of the SiC samples. Additionally, the ion-implanted samples had exhibited remarkable reductions in surface roughness, surface damage, and tensile residual stress.
基金The authors gratefully acknowledge the financial support by the National Natural Science Foundation of China(No.52405272)the CNOOC’s major project during the 14th Five-Year Plan period“Key Technologies and Equipment for Measurement,Recording,and Testing-Development and Engineering of Integrated Perforation Technology Equipment Based on Reservoir Geology”and the National Science Foundation of Jiangsu Province(No.BK20220533).
文摘Hydraulic sandblasting perforation plays a crucial role in the fracturing and reconstruction of unconventional oil and gas reservoirs.The jet nozzle is an essential part of the hydraulic perforation tool.Insufficient penetration depth,caused by excessive jet distances,presents challenges during the perforation process.To overcome this,an optimization design of the nozzle structure is required to enhance the perforation efficiency.In this paper,a computational fluid-dynamic model for conical-cylindrical nozzles has been elaborated.To further improve the rock-breaking efficiency of the jet nozzle,a fillet design is introduced at the nozzle inlet section.The SST k-ωmodel is employed to account for turbulent flow effects in submerged conditions.The results indicate that the nozzle’s geometric parameters greatly influence the flow characteristics.The orthogonal experimental method is employed to optimize the flow channel structure of the nozzle,taking the length of constant velocity core as the evaluation index.The following optimized geometric parameters for the conical-cylindrical nozzle have been determined accordingly:a cylindrical segment diameter of 3.2 mm,a contraction angle of 12°,a contraction segment length of 8 mm,a cylindrical segment length of 6.4 mm,and a fillet radius of 2 mm.
文摘This study aims to explore the potential of using a blended pulp from Mikania micrantha(M.micrantha)and waste paper for producing composite paper.The effects of the mass ratio of M.micrantha stem to waste paper(MRMW),the beating time(BT),the water-to-pulp mass ratio(WPMR)and the times of pulp suspension screening(TPSS)on the paper’s basic structural,optical and mechanical properties are investigated.It is found that MRMW primarily affects the grammage(mass per unit area),density,bulkness and whiteness;WPMR mainly affects the thickness and density;TPSS mainly affects the thickness and grammage.When MRMW is 3:7,the composite paper shows higher values for thickness,grammage,density and whiteness;whereas when MRMW is 7:3,these values are lower.Extending BT can increase paper density.The tensile strengths of all prepared samples fall in the range of 1.5 to 4.1 kN/m,indicating their excellent strength properties that meet the demands of many paper applications.The artistic bags and lampshades crafted from this composite paper exhibit a more natural texture compared to conventional packaging paper.This research demonstrates the feasibility of papermaking by using M.micrantha,while showcasing the potential for synergistic integration of waste resources with traditional hand papermaking techniques.
基金Supported by Self-funded Research Project of Administration of Traditional Chinese Medicine of Guangxi Zhuang Autonomous Region(GXZYA20220142)Key R&D Project of Guangxi Science and Technology Department(Guike AB21196057).
文摘[Objectives] To optimize the extraction process of Damp-clearing Mixture and establish the quality control indicators. [Methods] The extraction process of Coicis Semen Damp-clearing Mixture was optimized by L 9(3 4) orthogonal design with the content of total flavonoids and the dry yield rate as the evaluation indicators, and the amount of water, extraction time and extraction times as the factors, to determine the formation process of Coicis Semen Damp-clearing Mixture. In addition, the quality of the mixture was studied by thin layer chromatography (TLC). [Results] The optimal extraction process of Coicis Semen Damp-clearing Mixture was as follows: decocting twice, one hour each time, adding 8 times of water in the first time and 6 times of water in the second time, standing the extract in a cool place, adding 0.1% steviosin to facilitate the formation of the mixture;Acori Tatarinowii Rhizoma and Dendrophenol in the mixture were well separated by TLC with good reproducibility and specificity. [Conclusions] The preparation process and quality control indicators determined by the experiment are reasonable and feasible. It can provide a reference for the pilot production and quality standards of Coicis Semen Damp-clearing Mixture.
基金Important National Science & Technology Specific Projects (2009ZX04001-073)National Natural Science Foundation of China (51105025)
文摘In order to analyze the influence of configuration parameters on dynamic characteristics of machine tools in the working space, the configuration parameters have been suggested based on the orthogonal experiment method. Dynamic analysis of a milling machine, which is newly designed for producing turbine blades, has been conducted by utilizing the modal synthesis method. The finite element model is verified and updated by experimental modal analysis （EMA） of the machine tool. The result gained by modal synthesis method is compared with whole-model finite element method （FEM） result as well. According to the orthogonal experiment method, four configuration parameters of machine tool are considered as four factors for dynamic characteristics. The influence of configuration parameters on the first three natural frequencies is obtained by range analysis. It is pointed out that configuration parameter is the most important factor affecting the fundamental frequency of machine tools, and configuration parameter has less effect on lower-order modes of the system than others. The combination of configuration parameters which makes the fundamental frequency reach the maximum value is provided. Through demonstration, the conclusion can be drawn that the influence of configuration parameters on the natural frequencies of machine tools can be analyzed explicitly by the orthogonal experiment method, which offers a new method for estimating the dynamic characteristics of machine tools.
基金supported by National Natural Science Foundation of China(No.21067004)Research Fund for the Doctoral Program of Jiangxi University of Science and Technology(22020)
文摘Objective It is imperative to provide some consistent experimental results for the extraction of flavonid from Fructus Gardeniae. Methods The key extraction parameters that influenced the yield of flavonid from Fructus Gardeniae were optimized by employing an orthogonal experiment [L9（3）4], including the ratio of buffer solution （Na2B4O7· 10H2O） to raw material, concentration of Fructus Gardeniae in extracting solution, extraction time and pH of buffer solution. An UV/Vis detector was used to perform the qualitative and quantitative analyses of the extracted flavonid with the using of the standard sample. Results The maximum extraction yield of the crude extract was 5.0533 （mg/g） after 20 min when the mass ratio of Na2B4O7 · 10H2O to raw material was 0.4%, the concentration of Fructus Gardeniae in the extraction solution was 1/12 （g/mL）, and pH of buffer solution was 4.5. The positive reactions to the Molish and HCI-Mg tests suggested that the extracted compound was flavonoid, and FTIR measurements also identified the presence of flavonoid in the extracts. Conclusion This work is expected to provide a basis for further research, development, and utilization of Fructus gardenia in flavonid extraction.
基金supported by the Fundamental Research Funds for the Central Universities(K50511700004)the Natural Science Basic Research Plan in Shaanxi Province of China(2013JM1022)
文摘An integer linear bilevel programming problem is firstly transformed into a binary linear bilevel programming problem, and then converted into a single-level binary implicit programming. An orthogonal genetic algorithm is developed for solving the binary linear implicit programming problem based on the orthogonal design. The orthogonal design with the factor analysis, an experimental design method is applied to the genetic algorithm to make the algorithm more robust, statistical y sound and quickly convergent. A crossover operator formed by the orthogonal array and the factor analysis is presented. First, this crossover operator can generate a smal but representative sample of points as offspring. After al of the better genes of these offspring are selected, a best combination among these offspring is then generated. The simulation results show the effectiveness of the proposed algorithm.
基金Project supported by the National Hi-Tech R&D Program (863) of China (No. 2011AA7051001)the National Nature Science Foundation (No. 51205253) of China
文摘The optimization design of the power system is essential for stratospheric airships with paradoxical requirements of high reliability and low weight. The methodology of orthogonal experiment is presented to deal with the problem of the optimization design of the airship's power system. Mathematical models of the solar array, regenerative fuel cell, and power management subsystem (PMS) are presented. The basic theory of the method of orthogonal experiment is discussed, and the selection of factors and levels of the experiment and the choice of the evaluation function are also revealed. The proposed methodology is validated in the optimization design of the power system of the ZhiYuan-2 stratospheric airship. Results show that the optimal configuration is easily obtained through this methodology. Furthermore, the optimal configuration and three sub-optimal configurations are in the Pareto frontier of the design space. Sensitivity analyses for the weight and reliability of the airship's power system are presented.
基金Project (No. 51078377) supported by the National Natural Science Foundation of China
文摘This paper studies the excavation collapse at the Xianghu subway station on Hangzhou metro line 1.The objective is to present an overview of this case study and discuss the cause of the failure.Through field investigation and preliminary analysis,the reasons for the excavation collapse were the misuse of the soil parameters,over excavation,incorrect installation of steel struts,invalid monitoring data,and inadequate ground improvement.Finally,a small strain constitutive model was used for further analysis.In order to estimate damage efficiently,the orthogonal array(OA) was introduced for screening the key factor in the numerical experiments.Six estimated indexes including deformations and internal forces of the excavation were taken,and the effectiveness of four factors which may cause the collapse was evaluated.Through numerical experiments and interaction analysis,it is found that the deformation and internal force can be well controlled by jet grouting of the subsoil under the final cutting surface,but increasing the improvement ratio of the jet grouting cannot help optimize the excavation behavior efficiently,and without jet grouting and the fourth level struts,the deformation and internal force of the excavation in this case will far surpass the allowable value.
基金Supported by National Science&Technology Pillar Program of China(Grant No.2014BAB08B01)National Natural Science Foundation of China(Grant No.51409123)+1 种基金Jiangsu Provincial Natural Science Foundation of China(Grant No.BK20140554)Training Project for Young Core Teacher of Jiangsu University,China
文摘Cavitation is one of the most important performance of centrifugal pumps. However, the current optimization works of centrifugal pump are mostly focusing on hydraulic efficiency only, which may result in poor cavitation performance. Therefore, it is necessary to find an appropriate solution to improve cavitation performance with acceptable efficiency. In this paper, to improve the cavitation performance of a centrifugal pump with a vaned diffuser, the influence of impeller geometric parameters on the cavitation of the pump is investigated using the orthogonal design of experiment （DOE） based on computational fluid dynamics. The impeller inlet diameter D1, inlet incidence angle Aft, and blade wrap angle ~0 are selected as the main impeller geometric parameters and the orthogonal experiment of L9（3＂3） is performed. Three-dimensional steady simulations for cavitation are conducted by using constant gas mass fraction model with second-order upwind, and the predicated cavitation performance is validated by laboratory experiment. The optimization results are obtained by the range analysis method to improve cavitation performance without obvious decreasing the efficiency of the centrifugal pump. The internal flow of the pump is analyzed in order to identify the flow behavior that can affect cavitation performance. The results show that D1 has the greatest influence on the pump cavitation and the final optimized impeller provides better flow distribution at blade leading edge. The final optimized impeller accomplishes better cavitation and hydraulic performance and the NPSHR decreases by 0.63m compared with the original one. The presented work supplies a feasible route in engineering practice to optimize a centrifugal pump impeller for better cavitation performance.
基金Supported by Project of Sichuan Provincial Health Department(120385)Project of Sichuan Provincial Science and Technology Department(14JC0137)Project of Luzhou City Department of Science and Technology(2015LZCYDS09(2/8))
文摘[Objectives] To screen the optimal extraction conditions of flavonoids from leaves of Paliurus ramosissimus( Lour.) Poir.,measure the content of flavonoids in leaves of P. ramosissimus. using the Microplate Reader,and provide experimental basis for the development of medicinal resources of P. ramosissimus. [Methods] The ultrasonic extraction method was adopted and orthogonal design was carried out to study the effects of ethanol concentration( A),ultrasonic time( B),the solid-to-liquid ratio( C) on the extraction of flavonoids from leaves of P. ramosissimus. The Microplate Reader was used to measure the content of flavonoids in leaves of P. ramosissimus. in different extraction conditions,P. ramosissimus. and the optimal extraction conditions were used to measure the content of flavonoids from leaves of P. ramosissimus.[Results]Effects of the ultrasonic extraction method on the extraction rate of flavonoids from leaves of P. ramosissimus: extraction times >ethanol concentration > Ultrasound time > solid-liquid ratio. The screened optimal extraction process was: ethanol concentration of 65%,the solid-to-liquid ratio of 1∶ 25,ultrasonic time of 2 h and extraction times Under this condition,the extraction rate of total flavonoids in leaves of P. ramosissimus. was 2. 56%. [Conclusions] This method is simple and feasibility,reliable,and suitable for rapid measurement with large samples.
