A new statistical method, the fuzzy analytical method, was introduced in the optimization processes of liposome preparation. It took the full advantage of the information from orthogonal experiments to obtain the opti...A new statistical method, the fuzzy analytical method, was introduced in the optimization processes of liposome preparation. It took the full advantage of the information from orthogonal experiments to obtain the optimal liposome preparation conditions by considering all the evaluation indexes. Liposomes were made by the modified reverse-phase evaporation method and the properties of liposomes including size, encapsulation efficiency and physical stability were selected as the evaluation indexes to indicate the quality of liposomes. The experimental data of these properties were analyzed by three different methods including direct observation, variance analysis and fuzzy analytical method. The optimal preparation conditions obtained from these methods were validated with further experiments. The results of all possible combinations of levels for all factors in orthogonal experiments were acquired by the fuzzy analytical method. All evaluation indexes were taken into account and the optimal preparation condition was obtained. The optimal preparation conditions from direct observation and fuzzy analytical method were different and further validation studies indicated that the optimal conditions obtained from the fuzzy analytical method were in agreement with that from traditional statistical analysis. Fuzzy analytical method avoided the problem resulted from the traditional method, in which different levels of the same factor were obtained when considering different evaluation indexes. More information could be obtained from the fuzzy analytical method and the blind area within the experimental range was eliminated. As a result, fuzzy analytical method can be applied in the optimization processes of liposome preparation.展开更多
Aim New statistical method was applied in data analysis of orthogonal experiments to optimize the preparation of liposome. Method Particle size, zeta potential, encapsulation efficiency and physical stability of lipos...Aim New statistical method was applied in data analysis of orthogonal experiments to optimize the preparation of liposome. Method Particle size, zeta potential, encapsulation efficiency and physical stability of liposomes were selected by orthogonal design as evaluating indicators. Through three statistical methods （direct observation, variance analysis and stepwise multiple regression）, the optimized preparing conditions were acquired and validated by experiment. Results All of the four indicators were different by these analyses. The validation experiments indicated that the optimized conditions by stepwise multiple regressions were better than that by traditional analysis. Conclusion Experiment results suggested that multiple regressions could avoid the weakness of direct observation and variance analysis, but more work should be done in preparing liposomes.展开更多
To recycle residual iron efficiently in Bayer red mud, three-factor three-level orthogonal experiments on carbon-bearing pellets of Bayer red mud were conducted on the basis of their characteristics. The influences of...To recycle residual iron efficiently in Bayer red mud, three-factor three-level orthogonal experiments on carbon-bearing pellets of Bayer red mud were conducted on the basis of their characteristics. The influences of CaO dosage, temperature and roast- ing time on total iron content and iron recovery of reduced iron powder were studied. Results showed that these factors slightly influenced iron recovery, but significantly influenced total iron content. The principal factor influencing total iron content was CaO dosage, followed by temperature and roasting time. An increase in CaO dosage could decrease total iron content, whereas an increase in temperature and an extension of roasting time could improve total iron content. The reduced iron powder with total iron content of 88.4 l% and iron recovery rate of 97.97% can be obtained under the optimal conditions of temperature of 1 275 ℃, roasting time of 60 min and CaO dosage of 7.5%. The X-ray diffraction （XRD） and scanning electron microscopy （SEM） analyses of the reduced pellets showed that iron minerals in red mud were almost completely reduced to metallic iron. The principal factor influencing the total iron content of reduced iron powder was the grain size of metallic iron particles. An increase in CaO dosage hindered the growth of metallic iron particles, whereas an increase in temperature and an extension of roasting time could neutralise the effect of CaO dosage. Therefore, CaO dosage should be decreased when iron minerals in red mud can be adequately reduced into metallic iron.展开更多
Biological aerated filters have many advantages such as small volume and high treatment efficiency. This research focused on sewage treatment performance of integrated biological aerated filter (IBAF) under different ...Biological aerated filters have many advantages such as small volume and high treatment efficiency. This research focused on sewage treatment performance of integrated biological aerated filter (IBAF) under different conditions such as aeration, hydraulic retention time and the height of fillers layer, to identify the turn of marked affecting factor of removal performance through orthogonal experiments, optimize the function parameter of IBAF, reveal the regularity of sewage treatment of IBAF under different conditions, and adopt suitable measures to guarantee excess water quality of IBAF.展开更多
Orthogonal method was adopted to optimize the preozonation process and to minimize the bromate formation. Factors such as contact time, pH and ammonia concentration were investigated by orthogonal experiments to under...Orthogonal method was adopted to optimize the preozonation process and to minimize the bromate formation. Factors such as contact time, pH and ammonia concentration were investigated by orthogonal experiments to understand the interaction of various operation conditions on the formation of bromate and other disinfection byproducts(DBPs). Results showed that pH had the most significant influence on the minimization of bromate formation. The factors influencing the formation of bromate were in order of pH > contact time > ammonia concentration. For the formation of trihalomethanes(THMs) and haloacetic acids(HAAs), however, contact time significantly influenced their formation potential. In the practical preozonation process of waterworks, it is appropriate to set preozonation contact time to be 20 min. In order to minimize the formation of bromate, pH value of the raw water should be adjusted to 6. 0, and a certain concentration of ammonia could be added into the water to strengthen the minimization effect when the concentration of bromide in the raw water is higher than that in the experimental water.展开更多
The parameters of facial skin on human body were measured by Visia-CR,and the weight coefficients of each evaluation index were clarified by the analytic hierarchy process,thus the comprehensive score was calculated.T...The parameters of facial skin on human body were measured by Visia-CR,and the weight coefficients of each evaluation index were clarified by the analytic hierarchy process,thus the comprehensive score was calculated.The influence of four film-forming agents on the comprehensive score at different quality fractions was examined by single factor experiment to determine the level of each factor.In addition,the optimal proportion of the four film-forming agents was selected by combining multi-indicator comprehensive scoring method and orthogonal experiment.The results show that the best combination of the four film-forming agents in the 8 h wear test is A_(2)B_(2)C_(2)D_(1),and the quality fractions of each component are 2%of trimethylsiloxy silicate,1%of polydimethylsiloxane,2%of(acrylate(ester)/poly(dimethylsiloxane)copolymer,cyclopentasiloxane)and 0.5%of VP/hexadecene copolymer.展开更多
[Objective] This study aimed to explore optimum conditions for papain-as- sisted extraction of polysaccharides from Agrocybe aegirit. [Method] Because enzyme is capable of destroying organizational structure of cells,...[Objective] This study aimed to explore optimum conditions for papain-as- sisted extraction of polysaccharides from Agrocybe aegirit. [Method] Because enzyme is capable of destroying organizational structure of cells, papain was selected to cat- alyze cells to let polysaccharides out. An orthogonal experiment was carried out to investigate the effects of hydrolysis temperature, hydrolysis time, enzyme concentra- tion and solid to liquid ratio on extraction of polysaccharides from A. aegirit. [Result] Through the orthogonal experiment, the optimum papain-assisted extraction conditions were obtained： hydrolysis temperature, 45 ℃; hydrolysis time, 2 h; enzyme concen- tration 2%; solid to liquid ratio, 1：80. [Conclusion] This study will provide a reference for extraction of polysaccharides from A. aegirit.展开更多
In order to analyze the influence of configuration parameters on dynamic characteristics of machine tools in the working space, the configuration parameters have been suggested based on the orthogonal experiment metho...In order to analyze the influence of configuration parameters on dynamic characteristics of machine tools in the working space, the configuration parameters have been suggested based on the orthogonal experiment method. Dynamic analysis of a milling machine, which is newly designed for producing turbine blades, has been conducted by utilizing the modal synthesis method. The finite element model is verified and updated by experimental modal analysis （EMA） of the machine tool. The result gained by modal synthesis method is compared with whole-model finite element method （FEM） result as well. According to the orthogonal experiment method, four configuration parameters of machine tool are considered as four factors for dynamic characteristics. The influence of configuration parameters on the first three natural frequencies is obtained by range analysis. It is pointed out that configuration parameter is the most important factor affecting the fundamental frequency of machine tools, and configuration parameter has less effect on lower-order modes of the system than others. The combination of configuration parameters which makes the fundamental frequency reach the maximum value is provided. Through demonstration, the conclusion can be drawn that the influence of configuration parameters on the natural frequencies of machine tools can be analyzed explicitly by the orthogonal experiment method, which offers a new method for estimating the dynamic characteristics of machine tools.展开更多
Objective It is imperative to provide some consistent experimental results for the extraction of flavonid from Fructus Gardeniae. Methods The key extraction parameters that influenced the yield of flavonid from Fructu...Objective It is imperative to provide some consistent experimental results for the extraction of flavonid from Fructus Gardeniae. Methods The key extraction parameters that influenced the yield of flavonid from Fructus Gardeniae were optimized by employing an orthogonal experiment [L9（3）4], including the ratio of buffer solution （Na2B4O7· 10H2O） to raw material, concentration of Fructus Gardeniae in extracting solution, extraction time and pH of buffer solution. An UV/Vis detector was used to perform the qualitative and quantitative analyses of the extracted flavonid with the using of the standard sample. Results The maximum extraction yield of the crude extract was 5.0533 （mg/g） after 20 min when the mass ratio of Na2B4O7 · 10H2O to raw material was 0.4%, the concentration of Fructus Gardeniae in the extraction solution was 1/12 （g/mL）, and pH of buffer solution was 4.5. The positive reactions to the Molish and HCI-Mg tests suggested that the extracted compound was flavonoid, and FTIR measurements also identified the presence of flavonoid in the extracts. Conclusion This work is expected to provide a basis for further research, development, and utilization of Fructus gardenia in flavonid extraction.展开更多
An integer linear bilevel programming problem is firstly transformed into a binary linear bilevel programming problem, and then converted into a single-level binary implicit programming. An orthogonal genetic algorith...An integer linear bilevel programming problem is firstly transformed into a binary linear bilevel programming problem, and then converted into a single-level binary implicit programming. An orthogonal genetic algorithm is developed for solving the binary linear implicit programming problem based on the orthogonal design. The orthogonal design with the factor analysis, an experimental design method is applied to the genetic algorithm to make the algorithm more robust, statistical y sound and quickly convergent. A crossover operator formed by the orthogonal array and the factor analysis is presented. First, this crossover operator can generate a smal but representative sample of points as offspring. After al of the better genes of these offspring are selected, a best combination among these offspring is then generated. The simulation results show the effectiveness of the proposed algorithm.展开更多
The optimization design of the power system is essential for stratospheric airships with paradoxical requirements of high reliability and low weight. The methodology of orthogonal experiment is presented to deal with ...The optimization design of the power system is essential for stratospheric airships with paradoxical requirements of high reliability and low weight. The methodology of orthogonal experiment is presented to deal with the problem of the optimization design of the airship's power system. Mathematical models of the solar array, regenerative fuel cell, and power management subsystem (PMS) are presented. The basic theory of the method of orthogonal experiment is discussed, and the selection of factors and levels of the experiment and the choice of the evaluation function are also revealed. The proposed methodology is validated in the optimization design of the power system of the ZhiYuan-2 stratospheric airship. Results show that the optimal configuration is easily obtained through this methodology. Furthermore, the optimal configuration and three sub-optimal configurations are in the Pareto frontier of the design space. Sensitivity analyses for the weight and reliability of the airship's power system are presented.展开更多
This paper studies the excavation collapse at the Xianghu subway station on Hangzhou metro line 1.The objective is to present an overview of this case study and discuss the cause of the failure.Through field investiga...This paper studies the excavation collapse at the Xianghu subway station on Hangzhou metro line 1.The objective is to present an overview of this case study and discuss the cause of the failure.Through field investigation and preliminary analysis,the reasons for the excavation collapse were the misuse of the soil parameters,over excavation,incorrect installation of steel struts,invalid monitoring data,and inadequate ground improvement.Finally,a small strain constitutive model was used for further analysis.In order to estimate damage efficiently,the orthogonal array(OA) was introduced for screening the key factor in the numerical experiments.Six estimated indexes including deformations and internal forces of the excavation were taken,and the effectiveness of four factors which may cause the collapse was evaluated.Through numerical experiments and interaction analysis,it is found that the deformation and internal force can be well controlled by jet grouting of the subsoil under the final cutting surface,but increasing the improvement ratio of the jet grouting cannot help optimize the excavation behavior efficiently,and without jet grouting and the fourth level struts,the deformation and internal force of the excavation in this case will far surpass the allowable value.展开更多
Cavitation is one of the most important performance of centrifugal pumps. However, the current optimization works of centrifugal pump are mostly focusing on hydraulic efficiency only, which may result in poor cavitati...Cavitation is one of the most important performance of centrifugal pumps. However, the current optimization works of centrifugal pump are mostly focusing on hydraulic efficiency only, which may result in poor cavitation performance. Therefore, it is necessary to find an appropriate solution to improve cavitation performance with acceptable efficiency. In this paper, to improve the cavitation performance of a centrifugal pump with a vaned diffuser, the influence of impeller geometric parameters on the cavitation of the pump is investigated using the orthogonal design of experiment （DOE） based on computational fluid dynamics. The impeller inlet diameter D1, inlet incidence angle Aft, and blade wrap angle ~0 are selected as the main impeller geometric parameters and the orthogonal experiment of L9（3＂3） is performed. Three-dimensional steady simulations for cavitation are conducted by using constant gas mass fraction model with second-order upwind, and the predicated cavitation performance is validated by laboratory experiment. The optimization results are obtained by the range analysis method to improve cavitation performance without obvious decreasing the efficiency of the centrifugal pump. The internal flow of the pump is analyzed in order to identify the flow behavior that can affect cavitation performance. The results show that D1 has the greatest influence on the pump cavitation and the final optimized impeller provides better flow distribution at blade leading edge. The final optimized impeller accomplishes better cavitation and hydraulic performance and the NPSHR decreases by 0.63m compared with the original one. The presented work supplies a feasible route in engineering practice to optimize a centrifugal pump impeller for better cavitation performance.展开更多
[Objectives] To screen the optimal extraction conditions of flavonoids from leaves of Paliurus ramosissimus( Lour.) Poir.,measure the content of flavonoids in leaves of P. ramosissimus. using the Microplate Reader,and...[Objectives] To screen the optimal extraction conditions of flavonoids from leaves of Paliurus ramosissimus( Lour.) Poir.,measure the content of flavonoids in leaves of P. ramosissimus. using the Microplate Reader,and provide experimental basis for the development of medicinal resources of P. ramosissimus. [Methods] The ultrasonic extraction method was adopted and orthogonal design was carried out to study the effects of ethanol concentration( A),ultrasonic time( B),the solid-to-liquid ratio( C) on the extraction of flavonoids from leaves of P. ramosissimus. The Microplate Reader was used to measure the content of flavonoids in leaves of P. ramosissimus. in different extraction conditions,P. ramosissimus. and the optimal extraction conditions were used to measure the content of flavonoids from leaves of P. ramosissimus.[Results]Effects of the ultrasonic extraction method on the extraction rate of flavonoids from leaves of P. ramosissimus: extraction times >ethanol concentration > Ultrasound time > solid-liquid ratio. The screened optimal extraction process was: ethanol concentration of 65%,the solid-to-liquid ratio of 1∶ 25,ultrasonic time of 2 h and extraction times Under this condition,the extraction rate of total flavonoids in leaves of P. ramosissimus. was 2. 56%. [Conclusions] This method is simple and feasibility,reliable,and suitable for rapid measurement with large samples.展开更多
Polyvinylpyrrolidone K-30(PVP) was introduced into the preparation of nanozero-valent iron(n ZVI) and the traditional liquid-phase reduction was improved. The introduction of PVP simplified the traditional method.The ...Polyvinylpyrrolidone K-30(PVP) was introduced into the preparation of nanozero-valent iron(n ZVI) and the traditional liquid-phase reduction was improved. The introduction of PVP simplified the traditional method.The n ZVI prepared with this new approach showed excellent surface characters and high performance on the removal of cadmium. TEM results showed that the aggregates of n ZVI can reach to several micrometers in length but less than 100 nm in diameter. The iron particles that were enclosed by a layer of oxide film that is less than10 nm, demonstrated that the n ZVI possesses a core–shell structure. BET results indicate that the specific surface area of the n ZVI was 20.3159 m^2g^(-1). A three factor and three level orthogonal experiment was employed to find out the dominant factor that affects the removal rate of cadmium by n ZVI. Based on the range values, the prominence order of each factor was: initial p H of the solution N initial concentration of cadmium N dosage of n ZVI, the range was 96.453, 3.294 and 1.747, respectively. A simulation was performed under the same condition and a same conclusion was derived, this consistence confirmed the validity of the conclusion that p H is the most significant factor that affects the adsorption efficiency.展开更多
Carbon nanotubes (CNTs) have potential applications in many fields, chemical vapor deposition (CVD) is an effective method for CNTs preparation. By CVD, the catalytic pyrolysis temperature, pyrolysis time and the size...Carbon nanotubes (CNTs) have potential applications in many fields, chemical vapor deposition (CVD) is an effective method for CNTs preparation. By CVD, the catalytic pyrolysis temperature, pyrolysis time and the size of the raw gas flow have a great influence on yield rate of CNTs and their form. In this paper, the orthogonal experiment analysis method is used for studying the influence factors of yield rate of CNTs. Research results show that, in the suitable temperature range of preparing CNTs, there is relatively more CNTs with excellent morphology, otherwise, if the temperature is too low, the growth of CNTs will not be sufficient; if the temperature is too high, then CNTs will be generated with excessive defects; with longer growth time of suitable pyrolysis of CNTs, higher yield of CNTs will be obtained; CNTs morphology with reaction time is not proportional; too low or too high raw gas flow rate is not conducive to the growth of CNTs. We have found the optimum conditions for the CNTs preparation: pyrolysis temperature 68 degrees C, pyrolysis time 35 min, propylene flow rate of 180 mL/min. The results have a reference value for the preparation of CNTS and their composites.展开更多
The carbon fiber reinforced composite is a new type of composite material with an excellent property in strength and elastic modulus,and has found extensive applications in aerospace,energy,automotive industry and so ...The carbon fiber reinforced composite is a new type of composite material with an excellent property in strength and elastic modulus,and has found extensive applications in aerospace,energy,automotive industry and so on.However,this composite has a strict requirement on processing techniques,for example,brittle damage or delamination often exists in conventional processing techniques.Abrasive water jet machining technology is a new type of green machining technique with distinct advantages such as high-energy and thermal distortion free.The use of abrasive water jet technique to process carbon fiber composite materials has become a popular trend since it can significantly improve the processing accuracy and surface quality of carbon fiber composite materials.However,there are too many parameters that affect the quality of an abrasive water jet machining.At present,few studies are carried out on the parameter optimization of such a machining process,which leads to the unstable quality of surface processing.In this paper,orthogonal design of experiment and regression analysis were employed to establish the empirical model between cutting surface roughness and machining process parameters.Then a verified model was used to optimize the machining process parameters for abrasive water jet cutting carbon fiber reinforced composites.展开更多
To solve the problems of EDM when using the ordinary fluid and mold manufacturing,this paper provides the orthogonal experiment in the suspended powder fluid,which can optimize the main process parameters.And it also ...To solve the problems of EDM when using the ordinary fluid and mold manufacturing,this paper provides the orthogonal experiment in the suspended powder fluid,which can optimize the main process parameters.And it also achieves the technology of EDM in the suspended powder fluid primarily.展开更多
Parameter optimization integrating operation parameters and structure parameters for the purpose of high permeate flux,high productivity and low exergy consumption of direct contact membrane distillation (DCMD) proces...Parameter optimization integrating operation parameters and structure parameters for the purpose of high permeate flux,high productivity and low exergy consumption of direct contact membrane distillation (DCMD) process was conducted based on Taguchi experimental design. L16(45) orthogonal experiments were carried out with feed inlet temperature,permeate stream inlet temperature,flow rate,module packing density and length-diameter ratio as optimization parameters and with permeate flux,water productivity per unit volume of module and water production per unit exergy loss separately as optimization objectives. By using range analysis method,the dominance degree of the various influencing factors for the three objectives was analyzed and the optimum condition was obtained for the three objectives separately. Furthermore,the multi-objectives optimization was performed based on a weight grade method. The combined optimum conditions are feed inlet temperature 75℃,packing density 30% ,length-diameter ratio 10,permeate stream inlet temperature 30 ℃ and flow rate 25 L/h,which is in order of their dominance degree,and the validity of the optimization scheme was confirmed.展开更多
文摘A new statistical method, the fuzzy analytical method, was introduced in the optimization processes of liposome preparation. It took the full advantage of the information from orthogonal experiments to obtain the optimal liposome preparation conditions by considering all the evaluation indexes. Liposomes were made by the modified reverse-phase evaporation method and the properties of liposomes including size, encapsulation efficiency and physical stability were selected as the evaluation indexes to indicate the quality of liposomes. The experimental data of these properties were analyzed by three different methods including direct observation, variance analysis and fuzzy analytical method. The optimal preparation conditions obtained from these methods were validated with further experiments. The results of all possible combinations of levels for all factors in orthogonal experiments were acquired by the fuzzy analytical method. All evaluation indexes were taken into account and the optimal preparation condition was obtained. The optimal preparation conditions from direct observation and fuzzy analytical method were different and further validation studies indicated that the optimal conditions obtained from the fuzzy analytical method were in agreement with that from traditional statistical analysis. Fuzzy analytical method avoided the problem resulted from the traditional method, in which different levels of the same factor were obtained when considering different evaluation indexes. More information could be obtained from the fuzzy analytical method and the blind area within the experimental range was eliminated. As a result, fuzzy analytical method can be applied in the optimization processes of liposome preparation.
文摘Aim New statistical method was applied in data analysis of orthogonal experiments to optimize the preparation of liposome. Method Particle size, zeta potential, encapsulation efficiency and physical stability of liposomes were selected by orthogonal design as evaluating indicators. Through three statistical methods （direct observation, variance analysis and stepwise multiple regression）, the optimized preparing conditions were acquired and validated by experiment. Results All of the four indicators were different by these analyses. The validation experiments indicated that the optimized conditions by stepwise multiple regressions were better than that by traditional analysis. Conclusion Experiment results suggested that multiple regressions could avoid the weakness of direct observation and variance analysis, but more work should be done in preparing liposomes.
基金Sponsored by National High Technology Research and Development Program of China(2012AA06A109)
文摘To recycle residual iron efficiently in Bayer red mud, three-factor three-level orthogonal experiments on carbon-bearing pellets of Bayer red mud were conducted on the basis of their characteristics. The influences of CaO dosage, temperature and roast- ing time on total iron content and iron recovery of reduced iron powder were studied. Results showed that these factors slightly influenced iron recovery, but significantly influenced total iron content. The principal factor influencing total iron content was CaO dosage, followed by temperature and roasting time. An increase in CaO dosage could decrease total iron content, whereas an increase in temperature and an extension of roasting time could improve total iron content. The reduced iron powder with total iron content of 88.4 l% and iron recovery rate of 97.97% can be obtained under the optimal conditions of temperature of 1 275 ℃, roasting time of 60 min and CaO dosage of 7.5%. The X-ray diffraction （XRD） and scanning electron microscopy （SEM） analyses of the reduced pellets showed that iron minerals in red mud were almost completely reduced to metallic iron. The principal factor influencing the total iron content of reduced iron powder was the grain size of metallic iron particles. An increase in CaO dosage hindered the growth of metallic iron particles, whereas an increase in temperature and an extension of roasting time could neutralise the effect of CaO dosage. Therefore, CaO dosage should be decreased when iron minerals in red mud can be adequately reduced into metallic iron.
文摘Biological aerated filters have many advantages such as small volume and high treatment efficiency. This research focused on sewage treatment performance of integrated biological aerated filter (IBAF) under different conditions such as aeration, hydraulic retention time and the height of fillers layer, to identify the turn of marked affecting factor of removal performance through orthogonal experiments, optimize the function parameter of IBAF, reveal the regularity of sewage treatment of IBAF under different conditions, and adopt suitable measures to guarantee excess water quality of IBAF.
基金Supported by the National Natural Science Foundation of China(No.51008162)Natural Science Foundation of Tianjin(No.10JCYBJC03500)
文摘Orthogonal method was adopted to optimize the preozonation process and to minimize the bromate formation. Factors such as contact time, pH and ammonia concentration were investigated by orthogonal experiments to understand the interaction of various operation conditions on the formation of bromate and other disinfection byproducts(DBPs). Results showed that pH had the most significant influence on the minimization of bromate formation. The factors influencing the formation of bromate were in order of pH > contact time > ammonia concentration. For the formation of trihalomethanes(THMs) and haloacetic acids(HAAs), however, contact time significantly influenced their formation potential. In the practical preozonation process of waterworks, it is appropriate to set preozonation contact time to be 20 min. In order to minimize the formation of bromate, pH value of the raw water should be adjusted to 6. 0, and a certain concentration of ammonia could be added into the water to strengthen the minimization effect when the concentration of bromide in the raw water is higher than that in the experimental water.
文摘The parameters of facial skin on human body were measured by Visia-CR,and the weight coefficients of each evaluation index were clarified by the analytic hierarchy process,thus the comprehensive score was calculated.The influence of four film-forming agents on the comprehensive score at different quality fractions was examined by single factor experiment to determine the level of each factor.In addition,the optimal proportion of the four film-forming agents was selected by combining multi-indicator comprehensive scoring method and orthogonal experiment.The results show that the best combination of the four film-forming agents in the 8 h wear test is A_(2)B_(2)C_(2)D_(1),and the quality fractions of each component are 2%of trimethylsiloxy silicate,1%of polydimethylsiloxane,2%of(acrylate(ester)/poly(dimethylsiloxane)copolymer,cyclopentasiloxane)and 0.5%of VP/hexadecene copolymer.
基金Supported by Youth Fund of National Natural Science Foundation of China(31201242/C130405)Science Research Program of Education Department of Hubei Province(Q20143004)~~
文摘[Objective] This study aimed to explore optimum conditions for papain-as- sisted extraction of polysaccharides from Agrocybe aegirit. [Method] Because enzyme is capable of destroying organizational structure of cells, papain was selected to cat- alyze cells to let polysaccharides out. An orthogonal experiment was carried out to investigate the effects of hydrolysis temperature, hydrolysis time, enzyme concentra- tion and solid to liquid ratio on extraction of polysaccharides from A. aegirit. [Result] Through the orthogonal experiment, the optimum papain-assisted extraction conditions were obtained： hydrolysis temperature, 45 ℃; hydrolysis time, 2 h; enzyme concen- tration 2%; solid to liquid ratio, 1：80. [Conclusion] This study will provide a reference for extraction of polysaccharides from A. aegirit.
基金Important National Science & Technology Specific Projects (2009ZX04001-073)National Natural Science Foundation of China (51105025)
文摘In order to analyze the influence of configuration parameters on dynamic characteristics of machine tools in the working space, the configuration parameters have been suggested based on the orthogonal experiment method. Dynamic analysis of a milling machine, which is newly designed for producing turbine blades, has been conducted by utilizing the modal synthesis method. The finite element model is verified and updated by experimental modal analysis （EMA） of the machine tool. The result gained by modal synthesis method is compared with whole-model finite element method （FEM） result as well. According to the orthogonal experiment method, four configuration parameters of machine tool are considered as four factors for dynamic characteristics. The influence of configuration parameters on the first three natural frequencies is obtained by range analysis. It is pointed out that configuration parameter is the most important factor affecting the fundamental frequency of machine tools, and configuration parameter has less effect on lower-order modes of the system than others. The combination of configuration parameters which makes the fundamental frequency reach the maximum value is provided. Through demonstration, the conclusion can be drawn that the influence of configuration parameters on the natural frequencies of machine tools can be analyzed explicitly by the orthogonal experiment method, which offers a new method for estimating the dynamic characteristics of machine tools.
基金supported by National Natural Science Foundation of China(No.21067004)Research Fund for the Doctoral Program of Jiangxi University of Science and Technology(22020)
文摘Objective It is imperative to provide some consistent experimental results for the extraction of flavonid from Fructus Gardeniae. Methods The key extraction parameters that influenced the yield of flavonid from Fructus Gardeniae were optimized by employing an orthogonal experiment [L9（3）4], including the ratio of buffer solution （Na2B4O7· 10H2O） to raw material, concentration of Fructus Gardeniae in extracting solution, extraction time and pH of buffer solution. An UV/Vis detector was used to perform the qualitative and quantitative analyses of the extracted flavonid with the using of the standard sample. Results The maximum extraction yield of the crude extract was 5.0533 （mg/g） after 20 min when the mass ratio of Na2B4O7 · 10H2O to raw material was 0.4%, the concentration of Fructus Gardeniae in the extraction solution was 1/12 （g/mL）, and pH of buffer solution was 4.5. The positive reactions to the Molish and HCI-Mg tests suggested that the extracted compound was flavonoid, and FTIR measurements also identified the presence of flavonoid in the extracts. Conclusion This work is expected to provide a basis for further research, development, and utilization of Fructus gardenia in flavonid extraction.
基金supported by the Fundamental Research Funds for the Central Universities(K50511700004)the Natural Science Basic Research Plan in Shaanxi Province of China(2013JM1022)
文摘An integer linear bilevel programming problem is firstly transformed into a binary linear bilevel programming problem, and then converted into a single-level binary implicit programming. An orthogonal genetic algorithm is developed for solving the binary linear implicit programming problem based on the orthogonal design. The orthogonal design with the factor analysis, an experimental design method is applied to the genetic algorithm to make the algorithm more robust, statistical y sound and quickly convergent. A crossover operator formed by the orthogonal array and the factor analysis is presented. First, this crossover operator can generate a smal but representative sample of points as offspring. After al of the better genes of these offspring are selected, a best combination among these offspring is then generated. The simulation results show the effectiveness of the proposed algorithm.
基金Project supported by the National Hi-Tech R&D Program (863) of China (No. 2011AA7051001)the National Nature Science Foundation (No. 51205253) of China
文摘The optimization design of the power system is essential for stratospheric airships with paradoxical requirements of high reliability and low weight. The methodology of orthogonal experiment is presented to deal with the problem of the optimization design of the airship's power system. Mathematical models of the solar array, regenerative fuel cell, and power management subsystem (PMS) are presented. The basic theory of the method of orthogonal experiment is discussed, and the selection of factors and levels of the experiment and the choice of the evaluation function are also revealed. The proposed methodology is validated in the optimization design of the power system of the ZhiYuan-2 stratospheric airship. Results show that the optimal configuration is easily obtained through this methodology. Furthermore, the optimal configuration and three sub-optimal configurations are in the Pareto frontier of the design space. Sensitivity analyses for the weight and reliability of the airship's power system are presented.
基金Project (No. 51078377) supported by the National Natural Science Foundation of China
文摘This paper studies the excavation collapse at the Xianghu subway station on Hangzhou metro line 1.The objective is to present an overview of this case study and discuss the cause of the failure.Through field investigation and preliminary analysis,the reasons for the excavation collapse were the misuse of the soil parameters,over excavation,incorrect installation of steel struts,invalid monitoring data,and inadequate ground improvement.Finally,a small strain constitutive model was used for further analysis.In order to estimate damage efficiently,the orthogonal array(OA) was introduced for screening the key factor in the numerical experiments.Six estimated indexes including deformations and internal forces of the excavation were taken,and the effectiveness of four factors which may cause the collapse was evaluated.Through numerical experiments and interaction analysis,it is found that the deformation and internal force can be well controlled by jet grouting of the subsoil under the final cutting surface,but increasing the improvement ratio of the jet grouting cannot help optimize the excavation behavior efficiently,and without jet grouting and the fourth level struts,the deformation and internal force of the excavation in this case will far surpass the allowable value.
基金Supported by National Science&Technology Pillar Program of China(Grant No.2014BAB08B01)National Natural Science Foundation of China(Grant No.51409123)+1 种基金Jiangsu Provincial Natural Science Foundation of China(Grant No.BK20140554)Training Project for Young Core Teacher of Jiangsu University,China
文摘Cavitation is one of the most important performance of centrifugal pumps. However, the current optimization works of centrifugal pump are mostly focusing on hydraulic efficiency only, which may result in poor cavitation performance. Therefore, it is necessary to find an appropriate solution to improve cavitation performance with acceptable efficiency. In this paper, to improve the cavitation performance of a centrifugal pump with a vaned diffuser, the influence of impeller geometric parameters on the cavitation of the pump is investigated using the orthogonal design of experiment （DOE） based on computational fluid dynamics. The impeller inlet diameter D1, inlet incidence angle Aft, and blade wrap angle ~0 are selected as the main impeller geometric parameters and the orthogonal experiment of L9（3＂3） is performed. Three-dimensional steady simulations for cavitation are conducted by using constant gas mass fraction model with second-order upwind, and the predicated cavitation performance is validated by laboratory experiment. The optimization results are obtained by the range analysis method to improve cavitation performance without obvious decreasing the efficiency of the centrifugal pump. The internal flow of the pump is analyzed in order to identify the flow behavior that can affect cavitation performance. The results show that D1 has the greatest influence on the pump cavitation and the final optimized impeller provides better flow distribution at blade leading edge. The final optimized impeller accomplishes better cavitation and hydraulic performance and the NPSHR decreases by 0.63m compared with the original one. The presented work supplies a feasible route in engineering practice to optimize a centrifugal pump impeller for better cavitation performance.
基金Supported by Project of Sichuan Provincial Health Department(120385)Project of Sichuan Provincial Science and Technology Department(14JC0137)Project of Luzhou City Department of Science and Technology(2015LZCYDS09(2/8))
文摘[Objectives] To screen the optimal extraction conditions of flavonoids from leaves of Paliurus ramosissimus( Lour.) Poir.,measure the content of flavonoids in leaves of P. ramosissimus. using the Microplate Reader,and provide experimental basis for the development of medicinal resources of P. ramosissimus. [Methods] The ultrasonic extraction method was adopted and orthogonal design was carried out to study the effects of ethanol concentration( A),ultrasonic time( B),the solid-to-liquid ratio( C) on the extraction of flavonoids from leaves of P. ramosissimus. The Microplate Reader was used to measure the content of flavonoids in leaves of P. ramosissimus. in different extraction conditions,P. ramosissimus. and the optimal extraction conditions were used to measure the content of flavonoids from leaves of P. ramosissimus.[Results]Effects of the ultrasonic extraction method on the extraction rate of flavonoids from leaves of P. ramosissimus: extraction times >ethanol concentration > Ultrasound time > solid-liquid ratio. The screened optimal extraction process was: ethanol concentration of 65%,the solid-to-liquid ratio of 1∶ 25,ultrasonic time of 2 h and extraction times Under this condition,the extraction rate of total flavonoids in leaves of P. ramosissimus. was 2. 56%. [Conclusions] This method is simple and feasibility,reliable,and suitable for rapid measurement with large samples.
基金Supported by the National Natural Science Foundation of China(51278147)the Funds for Creative Research Groups of China(51121062)State Key Laboratory of Urban Water Resource and Environment(Harbin Institute of Technology)(2014TS02)
文摘Polyvinylpyrrolidone K-30(PVP) was introduced into the preparation of nanozero-valent iron(n ZVI) and the traditional liquid-phase reduction was improved. The introduction of PVP simplified the traditional method.The n ZVI prepared with this new approach showed excellent surface characters and high performance on the removal of cadmium. TEM results showed that the aggregates of n ZVI can reach to several micrometers in length but less than 100 nm in diameter. The iron particles that were enclosed by a layer of oxide film that is less than10 nm, demonstrated that the n ZVI possesses a core–shell structure. BET results indicate that the specific surface area of the n ZVI was 20.3159 m^2g^(-1). A three factor and three level orthogonal experiment was employed to find out the dominant factor that affects the removal rate of cadmium by n ZVI. Based on the range values, the prominence order of each factor was: initial p H of the solution N initial concentration of cadmium N dosage of n ZVI, the range was 96.453, 3.294 and 1.747, respectively. A simulation was performed under the same condition and a same conclusion was derived, this consistence confirmed the validity of the conclusion that p H is the most significant factor that affects the adsorption efficiency.
基金Funded by Beijing Excellent Talents Training Program(No.2014000020124G072)
文摘Carbon nanotubes (CNTs) have potential applications in many fields, chemical vapor deposition (CVD) is an effective method for CNTs preparation. By CVD, the catalytic pyrolysis temperature, pyrolysis time and the size of the raw gas flow have a great influence on yield rate of CNTs and their form. In this paper, the orthogonal experiment analysis method is used for studying the influence factors of yield rate of CNTs. Research results show that, in the suitable temperature range of preparing CNTs, there is relatively more CNTs with excellent morphology, otherwise, if the temperature is too low, the growth of CNTs will not be sufficient; if the temperature is too high, then CNTs will be generated with excessive defects; with longer growth time of suitable pyrolysis of CNTs, higher yield of CNTs will be obtained; CNTs morphology with reaction time is not proportional; too low or too high raw gas flow rate is not conducive to the growth of CNTs. We have found the optimum conditions for the CNTs preparation: pyrolysis temperature 68 degrees C, pyrolysis time 35 min, propylene flow rate of 180 mL/min. The results have a reference value for the preparation of CNTS and their composites.
基金National High-Tech R&D Program of China(863 Program)(2015AA043401)。
文摘The carbon fiber reinforced composite is a new type of composite material with an excellent property in strength and elastic modulus,and has found extensive applications in aerospace,energy,automotive industry and so on.However,this composite has a strict requirement on processing techniques,for example,brittle damage or delamination often exists in conventional processing techniques.Abrasive water jet machining technology is a new type of green machining technique with distinct advantages such as high-energy and thermal distortion free.The use of abrasive water jet technique to process carbon fiber composite materials has become a popular trend since it can significantly improve the processing accuracy and surface quality of carbon fiber composite materials.However,there are too many parameters that affect the quality of an abrasive water jet machining.At present,few studies are carried out on the parameter optimization of such a machining process,which leads to the unstable quality of surface processing.In this paper,orthogonal design of experiment and regression analysis were employed to establish the empirical model between cutting surface roughness and machining process parameters.Then a verified model was used to optimize the machining process parameters for abrasive water jet cutting carbon fiber reinforced composites.
文摘To solve the problems of EDM when using the ordinary fluid and mold manufacturing,this paper provides the orthogonal experiment in the suspended powder fluid,which can optimize the main process parameters.And it also achieves the technology of EDM in the suspended powder fluid primarily.
文摘Parameter optimization integrating operation parameters and structure parameters for the purpose of high permeate flux,high productivity and low exergy consumption of direct contact membrane distillation (DCMD) process was conducted based on Taguchi experimental design. L16(45) orthogonal experiments were carried out with feed inlet temperature,permeate stream inlet temperature,flow rate,module packing density and length-diameter ratio as optimization parameters and with permeate flux,water productivity per unit volume of module and water production per unit exergy loss separately as optimization objectives. By using range analysis method,the dominance degree of the various influencing factors for the three objectives was analyzed and the optimum condition was obtained for the three objectives separately. Furthermore,the multi-objectives optimization was performed based on a weight grade method. The combined optimum conditions are feed inlet temperature 75℃,packing density 30% ,length-diameter ratio 10,permeate stream inlet temperature 30 ℃ and flow rate 25 L/h,which is in order of their dominance degree,and the validity of the optimization scheme was confirmed.
