Group work method plays an important role in oral English teaching,and appropriate application of the group activities to oral English class can improve students'oral English effectively.This paper focus on the re...Group work method plays an important role in oral English teaching,and appropriate application of the group activities to oral English class can improve students'oral English effectively.This paper focus on the relationship between group work and oral English teaching,the principles,merits and the types of group works in oral English class.The aim is to improve the efficiency of oral English teaching and students'oral ability effectively.展开更多
Differently substituted benzimidazoles have been synthesized in very good yields in solvent-free conditions from o-phenylenediamine and aldehydes in the presence of BF3·OEt2 as a catalyst. The method is applicabl...Differently substituted benzimidazoles have been synthesized in very good yields in solvent-free conditions from o-phenylenediamine and aldehydes in the presence of BF3·OEt2 as a catalyst. The method is applicable to aromatic, unsaturated and aliphatic aldehydes and to substituted o-phenylenediamines without significant differences.展开更多
An efficient BF3.OEt2-promoted benzylation of arenes and heteroarenes with various benzyl ether derivatives has been developed. This method provided alternative access to valuable diarylmethane in good yields under mi...An efficient BF3.OEt2-promoted benzylation of arenes and heteroarenes with various benzyl ether derivatives has been developed. This method provided alternative access to valuable diarylmethane in good yields under mild conditions via an easy work-up procedure.展开更多
“一带一路”背景下,结合世界上护理领域最权威的国际护理专业英语技能认证考试(Occupational English Test for Nursing,OET),从优化课程理念、序化课程结构和建构习得式教学活动3个方面探讨基于国际职业资格标准的高职护理英语课程改...“一带一路”背景下,结合世界上护理领域最权威的国际护理专业英语技能认证考试(Occupational English Test for Nursing,OET),从优化课程理念、序化课程结构和建构习得式教学活动3个方面探讨基于国际职业资格标准的高职护理英语课程改革策略。展开更多
Automated parallel manipulation of multiple micro-objects with optoelectronic tweezers(OET)has brought significant research interests recently.However,the parallel manipulation of multiple objects in complex obstacle-...Automated parallel manipulation of multiple micro-objects with optoelectronic tweezers(OET)has brought significant research interests recently.However,the parallel manipulation of multiple objects in complex obstacle-dense microenvironment using OET technology based on negative dielectrophoresis(nDEP)remain a big technical challenge.In this work,we proposed an adaptive light pattern design strategy to achieve automated parallel OET manipulation of multiple micro-objects and navigate them through obstacles to target positions with high precision and no collision.We first developed a multi-micro-object parallel manipulation OET system,capable of simultaneous image processing and microparticles path planning.To overcome microparticle collisions caused by overlapping light patterns,we employed a novel adaptive light pattern design that can dynamically adjust the layout of overlapping light patterns according to surrounding environment,ensuring enough space for each microparticle and preventing unintended escapes from the OET trap.The efficacy of this approach has been verified through systematic simulations and experiments.Utilizing this strategy,multiple polystyrene microparticles were autonomously navigated through obstacles and microchannels to their intended destinations,demonstrating the strategy’s effectiveness and potential for automated parallel micromanipulation of multiple microparticles in complex and confined microenvironments.展开更多
BF3·OEte (Boron trifluoride etherate), an inexpensive and commercially easily available Lewis acid stoichiometrically employed for Beckamann rearrangement in general, was now found to efficiently catalyze Beckm...BF3·OEte (Boron trifluoride etherate), an inexpensive and commercially easily available Lewis acid stoichiometrically employed for Beckamann rearrangement in general, was now found to efficiently catalyze Beckmann rearrangement of ketoximes into their corresponding amides (up to 99% yield) in anhydrous acetonitrile under reflux temperature.展开更多
文摘Group work method plays an important role in oral English teaching,and appropriate application of the group activities to oral English class can improve students'oral English effectively.This paper focus on the relationship between group work and oral English teaching,the principles,merits and the types of group works in oral English class.The aim is to improve the efficiency of oral English teaching and students'oral ability effectively.
文摘Differently substituted benzimidazoles have been synthesized in very good yields in solvent-free conditions from o-phenylenediamine and aldehydes in the presence of BF3·OEt2 as a catalyst. The method is applicable to aromatic, unsaturated and aliphatic aldehydes and to substituted o-phenylenediamines without significant differences.
文摘An efficient BF3.OEt2-promoted benzylation of arenes and heteroarenes with various benzyl ether derivatives has been developed. This method provided alternative access to valuable diarylmethane in good yields under mild conditions via an easy work-up procedure.
基金the support from Optoseeker Biotechnology(Shenzhen)Co.,Ltd.to help build the OET system and provide Optobot 500 to carry out the experiment shown in supplementary Movie S4.National Key R&D Program of China(2023YFE0112400,2022YFA1207100,2024YFC3406900)National Natural Science Foundation of China(62103050,62473245,61933008)+6 种基金Beijing Municipal Natural Science Foundation(4242060,L246030)the Chongqing Municipal Natural Science Foundation(Grant No.2024NSCQJQX0192,CSTB2024NSCQ-JQX0034)the BIT Research and Innovation Promoting Project(Grant No.2023CX01002)Innovation Program of Shanghai Municipal Education Commission(2021-01-07-00-09-E0013)Shanghai Science and Technology plan project(23ZR1422300)Shenzhen Science and Technology Program(KJZD20240903101359020)Open Research Fund of Guangdong Provincial Key Laboratory of Advanced Biomaterials(Southern University of Science and Technology,Grant No.KLAB202404002).
文摘Automated parallel manipulation of multiple micro-objects with optoelectronic tweezers(OET)has brought significant research interests recently.However,the parallel manipulation of multiple objects in complex obstacle-dense microenvironment using OET technology based on negative dielectrophoresis(nDEP)remain a big technical challenge.In this work,we proposed an adaptive light pattern design strategy to achieve automated parallel OET manipulation of multiple micro-objects and navigate them through obstacles to target positions with high precision and no collision.We first developed a multi-micro-object parallel manipulation OET system,capable of simultaneous image processing and microparticles path planning.To overcome microparticle collisions caused by overlapping light patterns,we employed a novel adaptive light pattern design that can dynamically adjust the layout of overlapping light patterns according to surrounding environment,ensuring enough space for each microparticle and preventing unintended escapes from the OET trap.The efficacy of this approach has been verified through systematic simulations and experiments.Utilizing this strategy,multiple polystyrene microparticles were autonomously navigated through obstacles and microchannels to their intended destinations,demonstrating the strategy’s effectiveness and potential for automated parallel micromanipulation of multiple microparticles in complex and confined microenvironments.
基金Project supported by the National Natural Science Foundation of China (No. 20602011), New Century Excellent Talents in University, the Ministry of Education, China (No. NCET-07-0283), and ‘111' Project (No. B07023).
文摘BF3·OEte (Boron trifluoride etherate), an inexpensive and commercially easily available Lewis acid stoichiometrically employed for Beckamann rearrangement in general, was now found to efficiently catalyze Beckmann rearrangement of ketoximes into their corresponding amides (up to 99% yield) in anhydrous acetonitrile under reflux temperature.