The high-speed winding spindle employs a flexible support system incorporating rubber O-rings.By precisely configuring the structural parameters and the number of the O-rings,the spindle can stably surpass its critica...The high-speed winding spindle employs a flexible support system incorporating rubber O-rings.By precisely configuring the structural parameters and the number of the O-rings,the spindle can stably surpass its critical speed points and maintain operational stability across the entire working speed range.However,the support stiffness and damping of rubber O-rings exhibit significant nonlinear frequency dependence.Conventional experimental methods for deriving equivalent stiffness and damping,based on the principle of the forced non-resonance method,require fabricating custom setups for each O-ring specification and conducting vibration tests at varying frequencies,resulting in low efficiency and high costs.This study proposes a hybrid simulation-experimental method for dynamic parameter identification.Firstly,the frequency-dependent dynamic parameters of a specific O-ring support system are experimentally obtained.Subsequently,a corresponding parametric finite element model is established to simulate and solve the equivalent elastic modulus and equivalent stiffness-damping coefficient of this O-ring support system.Ultimately,after iterative simulation,the simulated and experimental results achieve a 99.7%agreement.The parametric finite element model developed herein can directly simulate and inversely estimate frequency-dependent dynamic parameters for O-rings of different specifications but identical elastic modulus.展开更多
A novel T-type specimen enabled the separation of the thermal and athermal contributions of electropulsing treatment(EPT)in pretwinned AZ31 Mg alloy.The combination of T-type geometry and carefully selected EPT condit...A novel T-type specimen enabled the separation of the thermal and athermal contributions of electropulsing treatment(EPT)in pretwinned AZ31 Mg alloy.The combination of T-type geometry and carefully selected EPT conditions equalized the thermal contributions at two distinct locations(J70-C and J77-D)in a thermally stable regime,which isolated the athermal effect in J70-C.The results were verified using finite element analysis.Although the athermal EPT contribution did not alter the fundamental microstructural evolution mechanisms,the evolution rate increased significantly.As a result,the J70-C region exhibited faster grain growth,annihilation of twin boundaries,reduction of low-angle grain boundaries,dislocation annihilation,and static recrystallization compared to its counterpart,as further supported by the microhardness trends.These results were interpreted in light of the additional driving force by the athermal EPT contribution,which accelerated the strain-induced boundary migrations beyond Joule heating alone.The proposed T-type specimen methodology offers a robust framework for decoupling the thermal and athermal effects in macroscale EPT processes.展开更多
The current research on secondary O-ring seals used in mechanical seals has begun to focus on their dynamic properties.However,detailed analysis of the dynamic properties of O-ring seals in spiral groove gas face seal...The current research on secondary O-ring seals used in mechanical seals has begun to focus on their dynamic properties.However,detailed analysis of the dynamic properties of O-ring seals in spiral groove gas face seals is lacking.In particular a transient study and a difference analysis of steady-state and transient performance are imperative.In this paper,a case study is performed to gauge the effect of secondary O-ring seals on the dynamic behavior(steady-state performance and transient performance)of face seals.A numerical finite element method(FEM)model is developed for the dynamic analysis of spiral groove gas face seals with a flexibly mounted stator in the axial and angular modes.The rotor tilt angle,static stator tilt angle and O-ring damping are selected to investigate the effect of O-ring seals on face seals during stable running operation.The results show that the angular factor can be ignored to save time in the simulation under small damping or undamped conditions.However,large O-ring damping has an enormous effect on the angular phase difference of mated rings,affecting the steady-state performance of face seals and largely increasing the possibility of face contact that reduces the service life of face seals.A pressure drop fluctuation is carried out to analyze the effect of O-ring seals on the transient performance of face seals.The results show that face seals could remain stable without support stiffness and O-ring damping during normal stable operation but may enter a large-leakage state when confronting instantaneous fluctuations.The oscillation-amplitude shortening effect of O-ring damping on the axial mode is much greater than that on the angular modes and O-ring damping prefers to cater for axial motion at the cost of angular motion.This research proposes a detailed dynamic-property study of O-ring seals in spiral groove gas face seals,to assist in the design of face seals.展开更多
Elastohydrodynamic lubrication characteristics of hydraulic reciprocating seals have significant effects on sealing and tribology performances of hydraulic actuators, especially in high parameter hydraulic systems. On...Elastohydrodynamic lubrication characteristics of hydraulic reciprocating seals have significant effects on sealing and tribology performances of hydraulic actuators, especially in high parameter hydraulic systems. Only elastic deformations of hydraulic reciprocating seals were discussed, and hydrodynamic effects were neglected in many studies. The physical process of the fluid-solid interaction effect did not be clearly presented in the existing fluid-solid interaction models for hydraulic reciprocating O-ring seals, and few of these models had been simultaneously validated through experiments. By exploring the physical process of the fluid-solid interaction effect of the hydraulic reciprocating O-ring seal, a numerical fluid-solid interaction model consisting of fluid lubrication, contact mechanics, asperity contact and elastic deformation analyses is constructed with an iterative procedure. With the SRV friction and wear tester, the experiments are performed to investigate the elastohydrodynamic lubrication characteristics of the O-ring seal. The regularity of the friction coefficient varying with the speed of reciprocating motion is obtained in the mixed lubrication condition. The experimental result is used to validate the fluid-solid interaction model. Based on the model, The elastohydrodynamic lubrication characteristics of the hydraulic reciprocating O-ring seal are presented respectively in the dry friction, mixed lubrication and full film lubrication conditions, including of the contact pressure, film thickness, friction coefficient, liquid film pressure and viscous shear stress in the sealing zone. The proposed numerical fluid-solid interaction model can be effectively used to analyze the operation characteristics of the hydraulic reciprocating O-ring seal, and can also be widely used to study other hydraulic reciprocating seals.展开更多
The nitrile butadiene rubber(NBR)hardness effect on the sealing characteristics of hydraulic O-ring rod seals is analyzed based on a mixed lubrication elastohydrodynamic model.Parameterized studies are conducted to re...The nitrile butadiene rubber(NBR)hardness effect on the sealing characteristics of hydraulic O-ring rod seals is analyzed based on a mixed lubrication elastohydrodynamic model.Parameterized studies are conducted to reveal the mechanism of the influence of rubber hardness on the static and dynamic behavior of seals.The optimized selections of rubber hardness are then investigated under different conditions.Results show that the low hardness seal is prone to stress concentration due to the extrusion effect under high pressure conditions;it is also more prone to leaking.A high hardness seal can better prevent leakage by reducing film thickness but it will cause large frictional power loss and increase the probability of wear failure.The choice of low hardness is recommended to reduce friction with the premise that leakage requirements are met.展开更多
Experimental studies on load decay and leak rate of O-rings made of two kindsof silicone rubber are conducted. The results show that the characteristic of load decay isrelative to the material and temperature of O-rin...Experimental studies on load decay and leak rate of O-rings made of two kindsof silicone rubber are conducted. The results show that the characteristic of load decay isrelative to the material and temperature of O-rings; the rate of load decay increases with the riseof temperature; the effects of load decay on leak rate of O-rings are negligible at roomtemperature, but they are notable at high temperature, and they are related to the material ofO-rings. On the basis of study on the theory of load decay and analysis to the results ofexperiments, a theoretical model is developed to describe the load decay characteristic of O-rings,and it matches the experimental data very well. By the study of time-temperature equivalence of loaddecay, the interconvertting equation of test data of load decay at different temperatures isobtained.展开更多
Overdenture as a treatment modality for both partially and fully edentulous patients is costeffective and less expensive. The purpose of the present study was to examine the newly fabricated attachments by comparing t...Overdenture as a treatment modality for both partially and fully edentulous patients is costeffective and less expensive. The purpose of the present study was to examine the newly fabricated attachments by comparing them with conventional O-ring attachment in vitro in terms of retention force and cyclic aging resistance. A total of 150 samples were prepared and divided into five groups according to the materials used(O-ring attachment, Deflex M10 XR, Deflex Classic SR, Deflex Acrilato FD, and flexible acrylic resin). The retention force of different attachments was measured by a mini dental implant after three subsequent aging(0, 63, and 126) cycles in the circumstances similar to the oral environment. The gap space between the head of the implant and the inner surface of the attachments was detected. Two-way analysis of variance(ANOVA) analysis with multiple comparisons test was applied for statistical analysis. The results showed that Deflex M10 XR had the highest retention force and the lowest gap space after cyclic aging; in addition, by comparing the relative force reduction, the lowest values were obtained in the O-ring attachment and the highest values in the flexible acrylic resin attachment. The retention force measured after cyclic aging for the Deflex M10 XR attachment was greatly improved when compared with the O-ring attachment and other types of attachment materials; in addition, the Deflex M10 XR attachment exhibited the minimum gap space between the inner surface and the mini dental implant head. In conclusion, Deflex M10 XR has the ability to withstand weathering conditions and retains its durable and retentive properties after aging when compared with other attachments.展开更多
The O-ring in the rotary dynamic sealing system of gas meters should have outstanding long-term sealing performance under the conditions of high and low temperature,which can ensure the safety of gas meters.In this pa...The O-ring in the rotary dynamic sealing system of gas meters should have outstanding long-term sealing performance under the conditions of high and low temperature,which can ensure the safety of gas meters.In this paper,based on the O-ring sealing mechanism,taking the compression set as the main sealing index,a finite element simulation method is used to analyze the failure charac-teristics under different conditions according to the constitutive relation of nitrile rubber.Then,using the orthogonal test method for the O-ring sealing performance index,the main factors which affect the law of long-term test are analysed,and the orthogonal regression mathematical model that can predict the compression set is obtained.Finally,the O-ring is improved according to the model,and the test results show that the performance of the new O-rings with high and low temperature resistance is greatly improved and meets the expected target requirements.展开更多
In this paper the behavior of an O-ring made of NBR rubber was investigated under extreme conditions. The effect of the extreme initial compression, operating pressure and extreme temperature conditions were examined....In this paper the behavior of an O-ring made of NBR rubber was investigated under extreme conditions. The effect of the extreme initial compression, operating pressure and extreme temperature conditions were examined. The rubber material was tested in simple tension, pure shear and equibiaxial tension modes complemented with a Dynamic Mechanical Thermal Analysis (DMTA) to capture the viscoelastic behavior of the material. For the investigation, a large-strain viscoelastic material model was developed by the authors, to take into account the large deformations caused by extreme conditions. Insufficient space during installation causes extreme initial compression consequently leading the material to crack on the contacting outer surfaces. It was found that the excessive strain and friction induced shear stress contributes primarily to this phenomenon. Extreme operating pressure causes the seal to penetrate into the gap between the shaft and the housing. This behavior damages the material and cracks appear on the seal. High strain areas were found in the proximity of the gap in the material. The analysis of the extreme operating temperature showed that during cooling the O-ring can completely loose its ability to seal at -70°C. There are three contributing factors: the speed of cooling, the temperature and the coefficient of thermal expansion.展开更多
BACKGROUND Endoscopic submucosal dissection(ESD)is a standardized therapeutic approach for early carcinoma of the digestive tracts.In this regard,the process of histopathological diagnosis requires standardization.How...BACKGROUND Endoscopic submucosal dissection(ESD)is a standardized therapeutic approach for early carcinoma of the digestive tracts.In this regard,the process of histopathological diagnosis requires standardization.However,the uneven development of healthcare in China,especially in eastern and western China,creates challenges for sharing a standardized diagnostic process.AIM To optimize the process of ESD specimen sampling,embedding and slide production,and to provide complete and accurate pathological reports.METHODS We established a practical process of specimen sampling,created standardized reporting templates,and trained pathologists from neighboring hospitals and those in the western region.A training effectiveness survey was conducted,and the collected data were assessed by the corresponding percentages.RESULTS A total of 111 valid feedback forms have been received,among which 58%of the participants obtained photographs during specimen collection,whereas the percentage increased to 79%after training.Only 58%and 62%of the respondents ensured the mucosal tissue strips were flat and their order remained unchanged;after training,these two proportions increased to 95%and 92%,respectively.Approximately half the participants measured the depth of the submucosal infiltration,which significantly increased to 95%after training.The percentage of pathologists who did not evaluate lymphovascular invasion effectively reduced.Only 22%of the participants had fixed clinic-pathological meetings before training,which increased to 49%after training.The number of participants who had a thorough understanding of endoscopic diagnosis also significantly increased.CONCLUSION There have been significant improvements in the process of specimen collection,section quality,and pathology reporting in trained hospitals.Therefore,our study provides valuable insights for others facing similar challenges.展开更多
The objective of this study is to evaluate the efficacy of laparoscopic surgery combined with the rectal inversion and specimen extraction(RIES)technique for rectal cancer,focusing on both short-term and long-term out...The objective of this study is to evaluate the efficacy of laparoscopic surgery combined with the rectal inversion and specimen extraction(RIES)technique for rectal cancer,focusing on both short-term and long-term outcomes.A retrospective comparative analysis was performed on 120 patients who underwent laparoscopic radical excision for rectal cancer from June 2017 to June 2021.Patients were categorized into two groups:Group RIES(n=58),which received the novel RIES technique,and Group AIES(n=62),which underwent the conventional abdominal incision for specimen extraction.Short-term outcomes,such as postoperative pelvic sepsis,temporary ileus,anastomotic leakage,and anastomotic stricture,were meticulously recorded.Longterm efficacy was evaluated through the 3-year overall survival(OS),disease-free survival(DFS),and local recurrence rate(LRR).The RIES group demonstrated a 3-year OS,DFS,and LRR of 86.2%,77.6%,and 8.6%,respectively,with a low incidence of short-term complications.Comparatively,the AIES group showed a 3-year OS,DFS,and LRR of 83.9%,74.2%,and 19.4%,respectively,with slightly higher rates of postoperative complications.Statistical analysis using the Student's t-test,the chi-square(χ^(2))test revealed no significant differences in the primary outcomes between the two groups,and suggested the noninferiority of the RIES technique.The study suggests that the RIES technique is a safe,feasible,and potentially functional and oncological superior approach to rectal cancer treatment,without compromising clinical efficacy.Further research is warranted to validate thesefindings in a larger,multicenter,and randomized controlled trial.展开更多
The paper designs a novel material-level specimen and its dedicated fixture suitable for applying Combined high-and low-Cycle Fatigue(CCF)loads.Unlike full-scale or simulation specimens,the CCF specimen eliminates geo...The paper designs a novel material-level specimen and its dedicated fixture suitable for applying Combined high-and low-Cycle Fatigue(CCF)loads.Unlike full-scale or simulation specimens,the CCF specimen eliminates geometrically induced stress gradients in the test region.Experimental data on CCF life and strain responses of ZSGH4169 alloy are acquired under different CCF loads.The Maximum Strain within Each(MSE)CCF cycle is demonstrated to be independent of the Low-Cycle Fatigue(LCF)loads and High-Cycle Fatigue(HCF)stress amplitudes,but exhibits a correlation with the Cycle Ratio of HCF/LCF(Rf).The growth law of MSE changes from linear to logarithmic as Rfdecreases.Strain amplitudes in the dwell stage,observed unaffected by Rf,are quantified as a function of LCF nominal stresses and HCF stress amplitudes.However,under a defined CCF load,strain amplitudes in the dwell stage remain constant.Strain peaks in the dwell stage in a single CCF cycle decrease in a power function with increasing HCF cycles.展开更多
基金National Key R&D Program of China(No.2017YFB1304000)Fundamental Research Funds for the Central Universities,China(No.2232023G-05-1)。
文摘The high-speed winding spindle employs a flexible support system incorporating rubber O-rings.By precisely configuring the structural parameters and the number of the O-rings,the spindle can stably surpass its critical speed points and maintain operational stability across the entire working speed range.However,the support stiffness and damping of rubber O-rings exhibit significant nonlinear frequency dependence.Conventional experimental methods for deriving equivalent stiffness and damping,based on the principle of the forced non-resonance method,require fabricating custom setups for each O-ring specification and conducting vibration tests at varying frequencies,resulting in low efficiency and high costs.This study proposes a hybrid simulation-experimental method for dynamic parameter identification.Firstly,the frequency-dependent dynamic parameters of a specific O-ring support system are experimentally obtained.Subsequently,a corresponding parametric finite element model is established to simulate and solve the equivalent elastic modulus and equivalent stiffness-damping coefficient of this O-ring support system.Ultimately,after iterative simulation,the simulated and experimental results achieve a 99.7%agreement.The parametric finite element model developed herein can directly simulate and inversely estimate frequency-dependent dynamic parameters for O-rings of different specifications but identical elastic modulus.
基金funded by the Defense Acquisition Program Administration(DAPA)(Grant No.KRIT-CT-23-059)supported by the‘Human Resources Program in Energy Technology’of the Korea Institute of Energy Technology Evaluation and Planning(KETEP),which was funded by the Ministry of Trade,Industry,and Energy(MOTIE)(Grant No.RS-2024-00398425).
文摘A novel T-type specimen enabled the separation of the thermal and athermal contributions of electropulsing treatment(EPT)in pretwinned AZ31 Mg alloy.The combination of T-type geometry and carefully selected EPT conditions equalized the thermal contributions at two distinct locations(J70-C and J77-D)in a thermally stable regime,which isolated the athermal effect in J70-C.The results were verified using finite element analysis.Although the athermal EPT contribution did not alter the fundamental microstructural evolution mechanisms,the evolution rate increased significantly.As a result,the J70-C region exhibited faster grain growth,annihilation of twin boundaries,reduction of low-angle grain boundaries,dislocation annihilation,and static recrystallization compared to its counterpart,as further supported by the microhardness trends.These results were interpreted in light of the additional driving force by the athermal EPT contribution,which accelerated the strain-induced boundary migrations beyond Joule heating alone.The proposed T-type specimen methodology offers a robust framework for decoupling the thermal and athermal effects in macroscale EPT processes.
基金Supported by National Key Basic Research Program of China(973Program,Grant No.2012CB026003)National Science and Technology Major Project of China(Grant No.ZX06901)
文摘The current research on secondary O-ring seals used in mechanical seals has begun to focus on their dynamic properties.However,detailed analysis of the dynamic properties of O-ring seals in spiral groove gas face seals is lacking.In particular a transient study and a difference analysis of steady-state and transient performance are imperative.In this paper,a case study is performed to gauge the effect of secondary O-ring seals on the dynamic behavior(steady-state performance and transient performance)of face seals.A numerical finite element method(FEM)model is developed for the dynamic analysis of spiral groove gas face seals with a flexibly mounted stator in the axial and angular modes.The rotor tilt angle,static stator tilt angle and O-ring damping are selected to investigate the effect of O-ring seals on face seals during stable running operation.The results show that the angular factor can be ignored to save time in the simulation under small damping or undamped conditions.However,large O-ring damping has an enormous effect on the angular phase difference of mated rings,affecting the steady-state performance of face seals and largely increasing the possibility of face contact that reduces the service life of face seals.A pressure drop fluctuation is carried out to analyze the effect of O-ring seals on the transient performance of face seals.The results show that face seals could remain stable without support stiffness and O-ring damping during normal stable operation but may enter a large-leakage state when confronting instantaneous fluctuations.The oscillation-amplitude shortening effect of O-ring damping on the axial mode is much greater than that on the angular modes and O-ring damping prefers to cater for axial motion at the cost of angular motion.This research proposes a detailed dynamic-property study of O-ring seals in spiral groove gas face seals,to assist in the design of face seals.
基金supported by National Basic Research Program of China(973 Program,Grant No. 2009CB724304)Key Research Program of the State Key Laboratory of Tribology of Tsinghua University,China (Grant No. SKLT08A06)National Natural Science Foundation of China(Grant No. 50975157)
文摘Elastohydrodynamic lubrication characteristics of hydraulic reciprocating seals have significant effects on sealing and tribology performances of hydraulic actuators, especially in high parameter hydraulic systems. Only elastic deformations of hydraulic reciprocating seals were discussed, and hydrodynamic effects were neglected in many studies. The physical process of the fluid-solid interaction effect did not be clearly presented in the existing fluid-solid interaction models for hydraulic reciprocating O-ring seals, and few of these models had been simultaneously validated through experiments. By exploring the physical process of the fluid-solid interaction effect of the hydraulic reciprocating O-ring seal, a numerical fluid-solid interaction model consisting of fluid lubrication, contact mechanics, asperity contact and elastic deformation analyses is constructed with an iterative procedure. With the SRV friction and wear tester, the experiments are performed to investigate the elastohydrodynamic lubrication characteristics of the O-ring seal. The regularity of the friction coefficient varying with the speed of reciprocating motion is obtained in the mixed lubrication condition. The experimental result is used to validate the fluid-solid interaction model. Based on the model, The elastohydrodynamic lubrication characteristics of the hydraulic reciprocating O-ring seal are presented respectively in the dry friction, mixed lubrication and full film lubrication conditions, including of the contact pressure, film thickness, friction coefficient, liquid film pressure and viscous shear stress in the sealing zone. The proposed numerical fluid-solid interaction model can be effectively used to analyze the operation characteristics of the hydraulic reciprocating O-ring seal, and can also be widely used to study other hydraulic reciprocating seals.
基金supported by the National Natural Science Foundation of China(No.52005470)the Natural Science Foundation of Zhejiang Province(No.LQ21E050020)the Fundamental Research Funds for the Provincial Universities of Zhejiang(No.2021YW17),China.
文摘The nitrile butadiene rubber(NBR)hardness effect on the sealing characteristics of hydraulic O-ring rod seals is analyzed based on a mixed lubrication elastohydrodynamic model.Parameterized studies are conducted to reveal the mechanism of the influence of rubber hardness on the static and dynamic behavior of seals.The optimized selections of rubber hardness are then investigated under different conditions.Results show that the low hardness seal is prone to stress concentration due to the extrusion effect under high pressure conditions;it is also more prone to leaking.A high hardness seal can better prevent leakage by reducing film thickness but it will cause large frictional power loss and increase the probability of wear failure.The choice of low hardness is recommended to reduce friction with the premise that leakage requirements are met.
基金This project is supported by 863 Program of China (No. 863-2-4-4-7).
文摘Experimental studies on load decay and leak rate of O-rings made of two kindsof silicone rubber are conducted. The results show that the characteristic of load decay isrelative to the material and temperature of O-rings; the rate of load decay increases with the riseof temperature; the effects of load decay on leak rate of O-rings are negligible at roomtemperature, but they are notable at high temperature, and they are related to the material ofO-rings. On the basis of study on the theory of load decay and analysis to the results ofexperiments, a theoretical model is developed to describe the load decay characteristic of O-rings,and it matches the experimental data very well. By the study of time-temperature equivalence of loaddecay, the interconvertting equation of test data of load decay at different temperatures isobtained.
文摘Overdenture as a treatment modality for both partially and fully edentulous patients is costeffective and less expensive. The purpose of the present study was to examine the newly fabricated attachments by comparing them with conventional O-ring attachment in vitro in terms of retention force and cyclic aging resistance. A total of 150 samples were prepared and divided into five groups according to the materials used(O-ring attachment, Deflex M10 XR, Deflex Classic SR, Deflex Acrilato FD, and flexible acrylic resin). The retention force of different attachments was measured by a mini dental implant after three subsequent aging(0, 63, and 126) cycles in the circumstances similar to the oral environment. The gap space between the head of the implant and the inner surface of the attachments was detected. Two-way analysis of variance(ANOVA) analysis with multiple comparisons test was applied for statistical analysis. The results showed that Deflex M10 XR had the highest retention force and the lowest gap space after cyclic aging; in addition, by comparing the relative force reduction, the lowest values were obtained in the O-ring attachment and the highest values in the flexible acrylic resin attachment. The retention force measured after cyclic aging for the Deflex M10 XR attachment was greatly improved when compared with the O-ring attachment and other types of attachment materials; in addition, the Deflex M10 XR attachment exhibited the minimum gap space between the inner surface and the mini dental implant head. In conclusion, Deflex M10 XR has the ability to withstand weathering conditions and retains its durable and retentive properties after aging when compared with other attachments.
基金Supported by the National Key Research and Development Program of China(No.2018YFC0808902).
文摘The O-ring in the rotary dynamic sealing system of gas meters should have outstanding long-term sealing performance under the conditions of high and low temperature,which can ensure the safety of gas meters.In this paper,based on the O-ring sealing mechanism,taking the compression set as the main sealing index,a finite element simulation method is used to analyze the failure charac-teristics under different conditions according to the constitutive relation of nitrile rubber.Then,using the orthogonal test method for the O-ring sealing performance index,the main factors which affect the law of long-term test are analysed,and the orthogonal regression mathematical model that can predict the compression set is obtained.Finally,the O-ring is improved according to the model,and the test results show that the performance of the new O-rings with high and low temperature resistance is greatly improved and meets the expected target requirements.
文摘In this paper the behavior of an O-ring made of NBR rubber was investigated under extreme conditions. The effect of the extreme initial compression, operating pressure and extreme temperature conditions were examined. The rubber material was tested in simple tension, pure shear and equibiaxial tension modes complemented with a Dynamic Mechanical Thermal Analysis (DMTA) to capture the viscoelastic behavior of the material. For the investigation, a large-strain viscoelastic material model was developed by the authors, to take into account the large deformations caused by extreme conditions. Insufficient space during installation causes extreme initial compression consequently leading the material to crack on the contacting outer surfaces. It was found that the excessive strain and friction induced shear stress contributes primarily to this phenomenon. Extreme operating pressure causes the seal to penetrate into the gap between the shaft and the housing. This behavior damages the material and cracks appear on the seal. High strain areas were found in the proximity of the gap in the material. The analysis of the extreme operating temperature showed that during cooling the O-ring can completely loose its ability to seal at -70°C. There are three contributing factors: the speed of cooling, the temperature and the coefficient of thermal expansion.
基金Supported by the Medical Education Research Project from Nanjing Drum Tower Hospital,No.2021-7the Clinical Trials Fund from Nanjing Drum Tower Hospital,No.2022-YXZX-XH-04National Natural Science Foundation of China,No.82203063.
文摘BACKGROUND Endoscopic submucosal dissection(ESD)is a standardized therapeutic approach for early carcinoma of the digestive tracts.In this regard,the process of histopathological diagnosis requires standardization.However,the uneven development of healthcare in China,especially in eastern and western China,creates challenges for sharing a standardized diagnostic process.AIM To optimize the process of ESD specimen sampling,embedding and slide production,and to provide complete and accurate pathological reports.METHODS We established a practical process of specimen sampling,created standardized reporting templates,and trained pathologists from neighboring hospitals and those in the western region.A training effectiveness survey was conducted,and the collected data were assessed by the corresponding percentages.RESULTS A total of 111 valid feedback forms have been received,among which 58%of the participants obtained photographs during specimen collection,whereas the percentage increased to 79%after training.Only 58%and 62%of the respondents ensured the mucosal tissue strips were flat and their order remained unchanged;after training,these two proportions increased to 95%and 92%,respectively.Approximately half the participants measured the depth of the submucosal infiltration,which significantly increased to 95%after training.The percentage of pathologists who did not evaluate lymphovascular invasion effectively reduced.Only 22%of the participants had fixed clinic-pathological meetings before training,which increased to 49%after training.The number of participants who had a thorough understanding of endoscopic diagnosis also significantly increased.CONCLUSION There have been significant improvements in the process of specimen collection,section quality,and pathology reporting in trained hospitals.Therefore,our study provides valuable insights for others facing similar challenges.
文摘The objective of this study is to evaluate the efficacy of laparoscopic surgery combined with the rectal inversion and specimen extraction(RIES)technique for rectal cancer,focusing on both short-term and long-term outcomes.A retrospective comparative analysis was performed on 120 patients who underwent laparoscopic radical excision for rectal cancer from June 2017 to June 2021.Patients were categorized into two groups:Group RIES(n=58),which received the novel RIES technique,and Group AIES(n=62),which underwent the conventional abdominal incision for specimen extraction.Short-term outcomes,such as postoperative pelvic sepsis,temporary ileus,anastomotic leakage,and anastomotic stricture,were meticulously recorded.Longterm efficacy was evaluated through the 3-year overall survival(OS),disease-free survival(DFS),and local recurrence rate(LRR).The RIES group demonstrated a 3-year OS,DFS,and LRR of 86.2%,77.6%,and 8.6%,respectively,with a low incidence of short-term complications.Comparatively,the AIES group showed a 3-year OS,DFS,and LRR of 83.9%,74.2%,and 19.4%,respectively,with slightly higher rates of postoperative complications.Statistical analysis using the Student's t-test,the chi-square(χ^(2))test revealed no significant differences in the primary outcomes between the two groups,and suggested the noninferiority of the RIES technique.The study suggests that the RIES technique is a safe,feasible,and potentially functional and oncological superior approach to rectal cancer treatment,without compromising clinical efficacy.Further research is warranted to validate thesefindings in a larger,multicenter,and randomized controlled trial.
基金co-supported by the National Natural Science Foundation of China(51805017)National Science and Technology Project(J2017-IV-0012-0049)+1 种基金National Science and Technology Project,China(J2019-IV-0007-0075)the Fundamental Research Funds for the Central Universities,China(JKF-20240036).
文摘The paper designs a novel material-level specimen and its dedicated fixture suitable for applying Combined high-and low-Cycle Fatigue(CCF)loads.Unlike full-scale or simulation specimens,the CCF specimen eliminates geometrically induced stress gradients in the test region.Experimental data on CCF life and strain responses of ZSGH4169 alloy are acquired under different CCF loads.The Maximum Strain within Each(MSE)CCF cycle is demonstrated to be independent of the Low-Cycle Fatigue(LCF)loads and High-Cycle Fatigue(HCF)stress amplitudes,but exhibits a correlation with the Cycle Ratio of HCF/LCF(Rf).The growth law of MSE changes from linear to logarithmic as Rfdecreases.Strain amplitudes in the dwell stage,observed unaffected by Rf,are quantified as a function of LCF nominal stresses and HCF stress amplitudes.However,under a defined CCF load,strain amplitudes in the dwell stage remain constant.Strain peaks in the dwell stage in a single CCF cycle decrease in a power function with increasing HCF cycles.
