Objective: to explore the application effect of neural monitor combined with nursing intervention in patients with thyroid surgery. Methods: 60 patients with thyroid surgery in our hospital from November 2019 to Novem...Objective: to explore the application effect of neural monitor combined with nursing intervention in patients with thyroid surgery. Methods: 60 patients with thyroid surgery in our hospital from November 2019 to November 2020 were randomly divided into two groups by digital table method. The control group was given routine nursing, and the research group was given neural monitor combined nursing intervention. The scores of unhealthy emotions, Pittsburgh sleep quality score and the incidence of recurrent nerve injury were compared between the two groups before and after nursing. Results: the score of unhealthy emotions in the study group was lower than that in the control group, the Pittsburgh sleep quality score was lower than that in the control group, and the incidence of recurrent nerve injury was lower than that in the control group, P < 0.05. Conclusion: neural monitor combined with nursing intervention is effective in patients with thyroid surgery, which can reduce unhealthy emotions, improve sleep quality and reduce complications.展开更多
The growing demand for advanced neural interfaces that enable precise brain monitoring and modulation has catalyzed significant research into flexible,biocompatible,and highly conductive materials.PEDOT:PSS-based bioe...The growing demand for advanced neural interfaces that enable precise brain monitoring and modulation has catalyzed significant research into flexible,biocompatible,and highly conductive materials.PEDOT:PSS-based bioelectronic materials exhibit high conductivity,mechanical flexibility,and biocompatibility,making them particularly suitable for integration into neural devices for brain science research.These materials facilitate high-resolution neural activity monitoring and provide precise electrical stimulation across diverse modalities.This review comprehensively examines recent advances in the development of PEDOT:PSS-based bioelectrodes for brain monitoring and modulation,with a focus on strategies to enhance their conductivity,biocompatibility,and long-term stability.Furthermore,it highlights the integration of multifunctional neural interfaces that enable synchronous stimulation-recording architectures,hybrid electro-optical stimulation modalities,and multimodal brain activity monitoring.These integrations enable fundamentally advancing the precision and clinical translatability of brain–computer interfaces.By addressing critical challenges related to efficacy,integration,safety,and clinical translation,this review identifies key opportunities for advancing next-generation neural devices.The insights presented are vital for guiding future research directions in the field and fostering the development of cutting-edge bioelectronic technologies for neuroscience and clinical applications.展开更多
Background:Even though the use of nerve monitoring during parotid gland surgery is not the gold standard to prevent damage to the nerve,it surely offers some advantages over the traditional approach.Different from thy...Background:Even though the use of nerve monitoring during parotid gland surgery is not the gold standard to prevent damage to the nerve,it surely offers some advantages over the traditional approach.Different from thyroid surgery,where a series of steps in intraoperative nerve monitoring have been described to confirm not only the integrity but—most importantly—the function of the recurrent laryngeal nerve,in parotid gland surgery,a formal guideline to follow while dissecting the facial nerve has yet to be described.Methods:A five‐year retrospective study was done reviewing the intraoperative records of patients who underwent parotid gland surgery under neural monitoring.The operative findings regarding the neuromonitoring process,particularly in regard to the amplitude of two main branches,were revised.A literature search was done to search for guidelines to follow when a facial nerve loss of signal is encountered.Results:Fifty‐five patients were operated on using the Nim 3 Nerve Monitoring System(Medtronic);31 were female patients,and 47 patients had benign lesions.Minimum changes were observed in the amplitude records after a comparison was made between the first and the last stimulation.There were only three articles discussing the term loss of signal during parotid gland surgery.Conclusion:Today,no sufficient attention has been given to the facial nerve monitoring process during parotidectomy.This study proposes a formal guideline to follow during this procedure as well as an instruction to consider when a loss of signal is observed to develop a uniform technique of facial nerve stimulation.展开更多
Light-field microscopy(LFM)enables rapid volumetric imaging through single-frame acquisition and fast 3D reconstruction algorithms.The high speed and low phototoxicity of LFM make it highly suitable for real-time 3D f...Light-field microscopy(LFM)enables rapid volumetric imaging through single-frame acquisition and fast 3D reconstruction algorithms.The high speed and low phototoxicity of LFM make it highly suitable for real-time 3D fluorescence imaging,such as studies of neural activity monitoring and blood flow analysis.However,in in vivo fluorescence imaging scenarios,the light intensity needs to be reduced as much as possible to achieve longer-term observations.The resulting low signal-to-noise ratio(SNR)caused by reduced light intensity significantly degrades the quality of 3D reconstruction in LFM.Existing deep-learning-based methods struggle to incorporate the structured intensity distribution and noise characteristics inherent to LFM data,often leading to artifacts and uneven energy distributions.To address these challenges,we propose the denoise-weighted view-channel-depth(DNW-VCD)network,integrating a two-step noise model and energy weight matrix into an LFM reconstruction framework.Additionally,we developed an attenuator-induced imaging system for dual-SNR image acquisition to validate DNW-VCD’s performance.Experimental results show that our method achieves artifact-reduced,realtime 3D imaging with isotropic resolution and lower phototoxicity,as verified through imaging of fluorescent beads,algae,and zebrafish heart.展开更多
文摘Objective: to explore the application effect of neural monitor combined with nursing intervention in patients with thyroid surgery. Methods: 60 patients with thyroid surgery in our hospital from November 2019 to November 2020 were randomly divided into two groups by digital table method. The control group was given routine nursing, and the research group was given neural monitor combined nursing intervention. The scores of unhealthy emotions, Pittsburgh sleep quality score and the incidence of recurrent nerve injury were compared between the two groups before and after nursing. Results: the score of unhealthy emotions in the study group was lower than that in the control group, the Pittsburgh sleep quality score was lower than that in the control group, and the incidence of recurrent nerve injury was lower than that in the control group, P < 0.05. Conclusion: neural monitor combined with nursing intervention is effective in patients with thyroid surgery, which can reduce unhealthy emotions, improve sleep quality and reduce complications.
基金supported by the Hospital-level scientific research fund of Yunfu People’s Hospital(A20231006)the Start-Up Fund for Introduced Talents and Scientific Research at Beijing Normal University(28709-312200502501)+11 种基金Overseas Expert Project of Guangdong Province(30802-110690303)National major project of brain science and brain-like research(2021ZD0204300)National major scientific research instrument development project(61827811)National Natural Science Foundation of China(22407015)Natural Science Foundation of Guangdong Province(2024A1515012271)Guangdong Provincial Pearl River Talents Program(2023QN10Y223)the start-up funding from Beijing Normal University(312200502504)Macao Science and Technology Development Fund(FDCT 0020/2019/AMJ and FDCT 0048/2021/AGJ)University of Macao(MYRGGRG2023-00038-FHS and MYRG2022-00054-FHS)Higher Education Fund of Macao SAR Government Natural Science Foundation of Guangdong Province(EF017/FHS-YZ/2021/GDST)the Macao Science and Technology Development Fund(FDCT 0014/2024/RIB1)Science Foundation of High-Level Talents of Wuyi University(2021AL002).
文摘The growing demand for advanced neural interfaces that enable precise brain monitoring and modulation has catalyzed significant research into flexible,biocompatible,and highly conductive materials.PEDOT:PSS-based bioelectronic materials exhibit high conductivity,mechanical flexibility,and biocompatibility,making them particularly suitable for integration into neural devices for brain science research.These materials facilitate high-resolution neural activity monitoring and provide precise electrical stimulation across diverse modalities.This review comprehensively examines recent advances in the development of PEDOT:PSS-based bioelectrodes for brain monitoring and modulation,with a focus on strategies to enhance their conductivity,biocompatibility,and long-term stability.Furthermore,it highlights the integration of multifunctional neural interfaces that enable synchronous stimulation-recording architectures,hybrid electro-optical stimulation modalities,and multimodal brain activity monitoring.These integrations enable fundamentally advancing the precision and clinical translatability of brain–computer interfaces.By addressing critical challenges related to efficacy,integration,safety,and clinical translation,this review identifies key opportunities for advancing next-generation neural devices.The insights presented are vital for guiding future research directions in the field and fostering the development of cutting-edge bioelectronic technologies for neuroscience and clinical applications.
文摘Background:Even though the use of nerve monitoring during parotid gland surgery is not the gold standard to prevent damage to the nerve,it surely offers some advantages over the traditional approach.Different from thyroid surgery,where a series of steps in intraoperative nerve monitoring have been described to confirm not only the integrity but—most importantly—the function of the recurrent laryngeal nerve,in parotid gland surgery,a formal guideline to follow while dissecting the facial nerve has yet to be described.Methods:A five‐year retrospective study was done reviewing the intraoperative records of patients who underwent parotid gland surgery under neural monitoring.The operative findings regarding the neuromonitoring process,particularly in regard to the amplitude of two main branches,were revised.A literature search was done to search for guidelines to follow when a facial nerve loss of signal is encountered.Results:Fifty‐five patients were operated on using the Nim 3 Nerve Monitoring System(Medtronic);31 were female patients,and 47 patients had benign lesions.Minimum changes were observed in the amplitude records after a comparison was made between the first and the last stimulation.There were only three articles discussing the term loss of signal during parotid gland surgery.Conclusion:Today,no sufficient attention has been given to the facial nerve monitoring process during parotidectomy.This study proposes a formal guideline to follow during this procedure as well as an instruction to consider when a loss of signal is observed to develop a uniform technique of facial nerve stimulation.
基金National Natural Science Foundation of China(T2221003,62025108,62071219,62371006)China Postdoctoral Science Foundation(GZC20230057)。
文摘Light-field microscopy(LFM)enables rapid volumetric imaging through single-frame acquisition and fast 3D reconstruction algorithms.The high speed and low phototoxicity of LFM make it highly suitable for real-time 3D fluorescence imaging,such as studies of neural activity monitoring and blood flow analysis.However,in in vivo fluorescence imaging scenarios,the light intensity needs to be reduced as much as possible to achieve longer-term observations.The resulting low signal-to-noise ratio(SNR)caused by reduced light intensity significantly degrades the quality of 3D reconstruction in LFM.Existing deep-learning-based methods struggle to incorporate the structured intensity distribution and noise characteristics inherent to LFM data,often leading to artifacts and uneven energy distributions.To address these challenges,we propose the denoise-weighted view-channel-depth(DNW-VCD)network,integrating a two-step noise model and energy weight matrix into an LFM reconstruction framework.Additionally,we developed an attenuator-induced imaging system for dual-SNR image acquisition to validate DNW-VCD’s performance.Experimental results show that our method achieves artifact-reduced,realtime 3D imaging with isotropic resolution and lower phototoxicity,as verified through imaging of fluorescent beads,algae,and zebrafish heart.
