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Journal of Mathematical Research with Applications Guide for Authors
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《Journal of Mathematical Research with Applications》 2025年第5期F0003-F0003,共1页
Journal overview:Journal of Mathematical Research with Applications(JMRA),formerly Journal of Mathematical Research and Exposition(JMRE)created in 1981,one of the transactions of China Society for Industrial and Appli... Journal overview:Journal of Mathematical Research with Applications(JMRA),formerly Journal of Mathematical Research and Exposition(JMRE)created in 1981,one of the transactions of China Society for Industrial and Applied Mathematics,is a home for original research papers of the highest quality in all areas of mathematics with applications.The target audience comprises:pure and applied mathematicians,graduate students in broad fields of sciences and technology,scientists and engineers interested in mathematics. 展开更多
关键词 academic journal applied mathematics mathematicS mathematical research research papers pure mathematics journal overview china society industrial applied mathematics
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Journal of Mathematical Research with Applications Guide for Authors
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《Journal of Mathematical Research with Applications》 2025年第6期F0003-F0003,共1页
Journal overview:Journal of Mathematical Research with Applications(JMRA),formerly Journal of Mathematical Research and Exposition(JMRE)created in 1981,one of the transactions of China Society for Industrial and Appli... Journal overview:Journal of Mathematical Research with Applications(JMRA),formerly Journal of Mathematical Research and Exposition(JMRE)created in 1981,one of the transactions of China Society for Industrial and Applied Mathematics,is a home for original research papers of the highest quality in all areas of mathematics with applications.The target audience comprises:pure and applied mathematicians,graduate students in broad fields of sciences and technology,scientists and engineers interested in mathematics. 展开更多
关键词 academic journal applied mathematics mathematicS mathematical research research papers pure mathematics journal overview china society industrial applied mathematics
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Journal of Mathematical Research with Applications Guide for Authors
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《Journal of Mathematical Research with Applications》 2025年第4期F0003-F0003,共1页
Journal overview:Journal of Mathematical Research with Applications(JMRA),formerly Journal of Mathematical Research and Exposition(JMRE)created in 1981,one of the transactions of China Society for Industrial and Appli... Journal overview:Journal of Mathematical Research with Applications(JMRA),formerly Journal of Mathematical Research and Exposition(JMRE)created in 1981,one of the transactions of China Society for Industrial and Applied Mathematics,is a home for original research papers of the highest quality in all areas of mathematics with applications.The target audience comprises:pure and applied mathematicians,graduate students in broad fields of sciences and technology,scientists and engineers interested in mathematics. 展开更多
关键词 academic journal applied mathematics mathematicS mathematical research research papers pure mathematics journal overview china society industrial applied mathematics
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Journal of Mathematical Research with Applications Guide for Authors
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《Journal of Mathematical Research with Applications》 2025年第3期F0003-F0003,共1页
Journal overview:Journal of Mathematical Research with Applications(JMRA),formerly Journal of Mathematical Research and Exposition(JMRE)created in 1981,one of the transactions of China Society for Industrial and Appli... Journal overview:Journal of Mathematical Research with Applications(JMRA),formerly Journal of Mathematical Research and Exposition(JMRE)created in 1981,one of the transactions of China Society for Industrial and Applied Mathematics,is a home for original research papers of the highest quality in all areas of mathematics with applications.The target audience comprises:pure and applied mathematicians,graduate students in broad felds of sciences and technology,scientists and engineers interested in mathematics. 展开更多
关键词 applied mathematics mathematicS mathematical research research papers pure mathematics journal overview
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Journal of Mathematical Research with Applications Guide for Authors
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《Journal of Mathematical Research with Applications》 2025年第2期F0003-F0003,共1页
Journal overview:Journal of Mathematical Research with Applications(JMRA),formerly Journal of Mathematical Research and Exposition(JMRE)created in 1981,one of the transactions of China Society for Industrial and Appli... Journal overview:Journal of Mathematical Research with Applications(JMRA),formerly Journal of Mathematical Research and Exposition(JMRE)created in 1981,one of the transactions of China Society for Industrial and Applied Mathematics,is a home for original research papers of the highest quality in all areas of mathematics with applications.The target audience comprises:pure and applied mathematicians,graduate students in broad fields of sciences and technology,scientists and engineers interested in mathematics. 展开更多
关键词 journal overview applied mathematics academic journal mathematical research research papers pure mathematics
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High-throughput and intelligent design of potential GRK2 inhibitor candidates using deep learning and mathematical programming methods
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作者 Yujing Zhao Qilei Liu +3 位作者 Jian Du Qingwei Meng Liang Sun Lei Zhang 《Chinese Journal of Chemical Engineering》 2025年第8期11-22,共12页
G protein coupled receptor kinase 2 (GRK2) is a kinase that regulates cardiac signaling activity. Inhibiting GRK2 is a promising mechanism for the treatment of heart failure (HF). Further development and optimization ... G protein coupled receptor kinase 2 (GRK2) is a kinase that regulates cardiac signaling activity. Inhibiting GRK2 is a promising mechanism for the treatment of heart failure (HF). Further development and optimization of inhibitors targeting GRK2 are highly meaningful. Therefore, in order to design GRK2 inhibitors with better performance, the most active molecule was selected as a reference compound from a data set containing 4-pyridylhydrazone derivatives and triazole derivatives, and its scaffold was extracted as the initial scaffold. Then, a powerful optimization-based framework for de novo drug design, guided by binding affinity, was used to generate a virtual molecular library targeting GRK2. The binding affinity of each virtual compound in this dataset was predicted by our developed deep learning model, and the designed potential compound with high binding affinity was selected for molecular docking and molecular dynamics simulation. It was found that the designed potential molecule binds to the ATP site of GRK2, which consists of key amino acids including Arg199, Gly200, Phe202, Val205, Lys220, Met274 and Asp335. The scaffold of the molecule is stabilized mainly by H-bonding and hydrophobic contacts. Concurrently, the reference compound in the dataset was also simulated by docking. It was found that this molecule also binds to the ATP site of GRK2. In addition, its scaffold is stabilized mainly by H-bonding and π-cation stacking interactions with Lys220, as well as hydrophobic contacts. The above results show that the designed potential molecule has similar binding modes to the reference compound, supporting the effectiveness of our framework for activity-focused molecular design. Finally, we summarized the interaction characteristics of general GRK2 inhibitors and gained insight into their molecule-target binding mechanisms, thereby facilitating the expansion of lead to hit compound. 展开更多
关键词 mathematical modeling Optimal design Product design GRK2 mathematical programmingmethod Binding affinity
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Journal of Mathematical Research with Applications Guide for Authors
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《Journal of Mathematical Research with Applications》 2025年第1期F0003-F0003,共1页
Journal overview:Journal of Mathematical Research with Applications(JMRA),formerly Journal of Mathematical Research and Exposition(JMRE)created in 1981,one of the transactions of China Society for Industrial and Appli... Journal overview:Journal of Mathematical Research with Applications(JMRA),formerly Journal of Mathematical Research and Exposition(JMRE)created in 1981,one of the transactions of China Society for Industrial and Applied Mathematics,is a home for original research papers of the highest quality in all areas of mathematics with applications.The target audience comprises:pure and applied mathematicians,graduate students in broad fields of sciences and technology,scientists and engineers interested in mathematics. 展开更多
关键词 mathematicAL mathematicS INTERESTED
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Mathematical principle and engineering application of end-mining technology with non-pillar
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作者 Jianyong Qiao Zhiqiang Wang +1 位作者 Tingzhao Li Yun Zhao 《Earth Energy Science》 2025年第1期85-97,共13页
To ameliorate the difficulties of on-site dynamic disaster control in the end-mining stage of traditional mining engineering,this paper introduces the mathematical research and engineering application of the end-minin... To ameliorate the difficulties of on-site dynamic disaster control in the end-mining stage of traditional mining engineering,this paper introduces the mathematical research and engineering application of the end-mining technology system with non-pillar in mines(ETSNM)in recent years.The petal warning criterion for the stability of the surrounding rock of the roadway at the end-mining stage was obtained by studying the inverse problem of the petal theorem.A conformal mathematical model of the end-mining stage was established using the conformal mapping method,and the limit theorem of the peak point of mine pressure(LTPPMP)in the end-mining stage was demonstrated.Based on the cross-fusion of the above basic mathematical theory and the LTPPMP,a new ETSNM model was proposed,which includes no coal pillar,no dedicated retracement roadways,and fast retracement equipment(NNF).The mathematical principles of engineering technology for height control,speed limit,and roof cutting in the end-mining stage with non-pillar were revealed.The scientific and application values of the ETSNM were confirmed through engineering applications.Based on this,a new non-pillar control technology for dynamic disasters in the end-mining stage was proposed.The above research will play an active role in promoting the engineering application of ETSNM driven by mathematical theory. 展开更多
关键词 NON-PILLAR End-mining technology mathematical principle Engineering application Dynamic disaster
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Exploration and Practice of the Application of Eye-Tracking Technology in University Mathematics Teaching
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作者 Zejun Wang Mei Yang +1 位作者 Xingjing Fan Mingyang Li 《Journal of Contemporary Educational Research》 2025年第9期244-249,共6页
As a tool for quantifying individuals’visual attention and information processing,eye-tracking technology is gradually being applied in the reform of higher education.This paper focuses on issues in university mathem... As a tool for quantifying individuals’visual attention and information processing,eye-tracking technology is gradually being applied in the reform of higher education.This paper focuses on issues in university mathematics teaching,such as heavy cognitive load,delayed feedback,and insufficient adaptability.Based on theories of cognitive psychology,the study explores application pathways of this technology in cognitive diagnosis,instructional optimization,classroom regulation,personalized support,and teaching assessment.Research shows that eye-tracking data can reveal key cognitive features during the learning process,enhance the visualization of instructional feedback,and improve the scientific basis of decision-making.This provides both theoretical support and practical reference for data-driven and precise transformation in university mathematics education. 展开更多
关键词 Eye tracking University mathematics Teaching reform Data driven
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A Practical Study of Teaching Propositions in High School Mathematics Based on the TPACK Framework
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作者 Jianping Luo 《Journal of Contemporary Educational Research》 2025年第7期56-64,共9页
Under the background of information technology in education,there is insufficient integration of technological knowledge,pedagogical knowledge,and subject content knowledge in the teaching of propositions in high scho... Under the background of information technology in education,there is insufficient integration of technological knowledge,pedagogical knowledge,and subject content knowledge in the teaching of propositions in high school mathematics.Teachers mostly equate information technology with multimedia presentations,and students often memorize formulas mechanically,which leads to difficulties in the application of complex propositions.In this study,we take“the cosine formula of the difference between two angles”as an example.Based on the TPACK framework,we use contextual teaching and geometric drawing board demonstration to integrate subject content,pedagogical knowledge,and technological knowledge in teaching design and practice.It is found that by dynamically displaying the derivation process of the formula and guiding students to explore independently,it can help them understand the logic of the formula and improve their application ability.This study provides a paradigm for teaching propositions in high school mathematics and suggests that the TPACK framework can facilitate knowledge integration and cultivate students’mathematical literacy such as problem posing and creative inquiry,which is of great significance for teaching practice. 展开更多
关键词 TPACK High school mathematics Propositional teaching Teaching practice
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Research and Practice of a Knowledge Graph- Driven Inquiry-Construction Double-Helix Teaching Model in High School Mathematics
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作者 Deqiang Li Haiying Zhang 《Journal of Contemporary Educational Research》 2025年第11期62-69,共8页
In the context of the“Two New”initiatives,high school mathematics instruction still grapples with three interlocking problems:knowledge fragmentation,limited cultivation of higher-order thinking,and weak alignment a... In the context of the“Two New”initiatives,high school mathematics instruction still grapples with three interlocking problems:knowledge fragmentation,limited cultivation of higher-order thinking,and weak alignment among teaching,learning,and assessment.To counter these challenges,we propose an Inquiry-Construction Double-Helix model that uses a domain-specific knowledge graph as its cognitive spine.The model interweaves two mutually reinforcing strands-student-driven inquiry and systematic knowledge construction-into a double-helix trajectory analogous to DNA replication.The Inquiry Strand is launched by authentic,situation-based tasks that shepherd students through the complete cycle:question→hypothesis→verification→reflection.The Construction Strand simultaneously externalizes,restructures,and internalizes core disciplinary concepts via visual,hierarchical knowledge graphs.Within the flow of a lesson,the two strands alternately dominate and scaffold each other,securing the co-development of conceptual understanding,procedural fluency,and mathematical literacy.Empirical evidence demonstrates that this model significantly enhances students’systematic knowledge integration,problem-solving transfer ability,and core mathematical competencies,offering a replicable and operable teaching paradigm and practical pathway for deepening high school mathematics classroom reform. 展开更多
关键词 Knowledge graph Inquiry-construction Teaching model High school mathematics
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Study on Improving the Teaching Effect of Mathematical Methods for Physics Using Manim Animation Technology
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作者 Yong Niu Linhao Wang +1 位作者 Ying Wang Pan Wang 《Journal of Contemporary Educational Research》 2025年第10期215-222,共8页
With the development of educational digitalization,how to effectively apply digital animation technology to traditional classroom teaching has become an urgent problem to be solved.This study explores the application ... With the development of educational digitalization,how to effectively apply digital animation technology to traditional classroom teaching has become an urgent problem to be solved.This study explores the application of Manim in the course of Mathematical Methods for Physics.Taking the visualization of Fourier series,complex numbers,and other content as examples,it improves students’understanding of complex and abstract mathematical physics concepts through dynamic and visual teaching methods.The teaching effect shows that Manim helps to enhance students’learning experience,improve teaching efficiency and effectiveness,and has a positive impact on students’active learning ability.The research in this paper can provide references and inspiration for the educational digitalization of higher education. 展开更多
关键词 Manim mathematical methods for physics Educational digitalization Animation visualization
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The Construction of a New System for University Mathematics Teaching Based on Ability Cultivation
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作者 Lifeng Guo 《Journal of Contemporary Educational Research》 2025年第7期292-298,共7页
To meet the demands of higher education reform and innovative talent cultivation,the teaching team of Tarim University,with ability cultivation as the core,has established a new“331”university mathematics teaching s... To meet the demands of higher education reform and innovative talent cultivation,the teaching team of Tarim University,with ability cultivation as the core,has established a new“331”university mathematics teaching system.Through the multi-dimensional linkage of master teachers’guidance,course optimization,stratified teaching,practical reinforcement,and competition-driven,it has significantly improved students’mathematical application ability and innovative quality. 展开更多
关键词 University mathematics Teaching system Ability cultivation
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Investigating the Role of Antimalarial Treatment and Mosquito Nets in Malaria Transmission and Control through Mathematical Modeling
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作者 Azhar Iqbal Kashif Butt Tariq Ismaeel +4 位作者 Sara Khan Muhammad Imran Waheed Ahmad Ismail Abdulrashid Muhammad Sajid Riaz 《Computer Modeling in Engineering & Sciences》 2025年第9期3463-3492,共30页
Malaria is a significant global health challenge.This devastating disease continues to affect millions,especially in tropical regions.It is caused by Plasmodium parasites transmitted by female Anopheles mosquitoes.Thi... Malaria is a significant global health challenge.This devastating disease continues to affect millions,especially in tropical regions.It is caused by Plasmodium parasites transmitted by female Anopheles mosquitoes.This study introduces a nonlinear mathematical model for examining the transmission dynamics of malaria,incorporating both human and mosquito populations.We aim to identify the key factors driving the endemic spread of malaria,determine feasible solutions,and provide insights that lead to the development of effective prevention and management strategies.We derive the basic reproductive number employing the next-generation matrix approach and identify the disease-free and endemic equilibrium points.Stability analyses indicate that the disease-free equilibrium is locally and globally stable when the reproductive number is below one,whereas an endemic equilibrium persists when this threshold is exceeded.Sensitivity analysis identifies the most influential mosquito-related parameters,particularly the bite rate and mosquito mortality,in controlling the spread of malaria.Furthermore,we extend our model to include a treatment compartment and three disease-preventive control variables such as antimalaria drug treatments,use of larvicides,and the use of insecticide-treated mosquito nets for optimal control analysis.The results show that optimal use of mosquito nets,use of larvicides for mosquito population control,and treatment can lower the basic reproduction number and control malaria transmission with minimal intervention costs.The analysis of disease control strategies and findings offers valuable information for policymakers in designing cost-effective strategies to combat malaria. 展开更多
关键词 MALARIA mathematical modeling optimal control mosquito nets anti-malaria drugs stability and sensitivity analysis
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Reform and Practice of Ideological and Political Education in Advanced Mathematics under the OBE Concept
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作者 Zejun Wang Mei Yang Peng Ma 《Journal of Contemporary Educational Research》 2025年第9期420-424,共5页
In the context of the new era of education,advanced mathematics not only undertakes the function of knowledge transmission but also plays a vital role in cultivating logical thinking,scientific spirit,and value orient... In the context of the new era of education,advanced mathematics not only undertakes the function of knowledge transmission but also plays a vital role in cultivating logical thinking,scientific spirit,and value orientation.However,traditional teaching has overemphasized knowledge instillation while neglecting value guidance,making it difficult to meet the demands of cultivating interdisciplinary talents.This study introduces the OBE concept and constructs a“knowledge–ability–value”teaching framework,integrating outcome orientation,backward design,and diversified evaluation to promote the systematic incorporation of ideological and political education into the curriculum.Taking limits,definite integrals,and series as representative knowledge points,the paper designs case-based pathways to foster dialectical thinking,patriotism,and scientific spirit.Practice has shown that this model effectively unifies knowledge education and value education,enhancing students’logical reasoning,sense of responsibility,and scientific literacy.The study provides an operational pathway for the reform of ideological and political education in advanced mathematics courses and carries practical significance for implementing the goal of“all-round education.” 展开更多
关键词 OBE concept Advanced mathematics Ideological and political education Teaching reform Case-based teaching
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Logic and Practice of Ideological and Political Thinking in Advanced Mathematics Courses
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作者 Yaxian Hao Keyan Liu 《Journal of Contemporary Educational Research》 2025年第6期42-49,共8页
As a fundamental course in science and engineering education at universities,advanced mathematics plays an irreplaceable role in cultivating students’logical thinking,scientific spirit,and comprehensive qualities.Int... As a fundamental course in science and engineering education at universities,advanced mathematics plays an irreplaceable role in cultivating students’logical thinking,scientific spirit,and comprehensive qualities.Integrating ideological and political education into advanced mathematics teaching is not only an inevitable requirement for achieving the goal of“three-dimensional and holistic education”but also a crucial path for promoting students’comprehensive development.This article delves into the necessary logic,practical possibilities,and real-world challenges of ideological and political education in advanced mathematics courses,systematically analyzing the implementation pathways and illustrating practical approaches through specific cases.Meanwhile,to address issues such as insufficient teacher capability,lagging resource development,disconnected instructional design,and inadequate evaluation mechanisms encountered during implementation,this article proposes practical improvement strategies.It aims to provide theoretical insights and practical guidance for the further advancement of ideological and political education in advanced mathematics courses. 展开更多
关键词 Advanced mathematics Curriculum ideology and politics Logical framework Practical pathways
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Mathematical modeling of trypanosomiasis control strategies in communities where human,cattle and wildlife interact
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作者 Mlyashimbi Helikumi Steady Mushayabasa 《Animal Diseases》 2025年第3期355-369,共15页
Spillover of trypanosomiasis parasites from wildlife to domestic livestock and humans remains a major challenge world over.With the disease targeted for elimination by 2030,assessing the impact of control strategies i... Spillover of trypanosomiasis parasites from wildlife to domestic livestock and humans remains a major challenge world over.With the disease targeted for elimination by 2030,assessing the impact of control strategies in communities where there are human-cattle-wildlife interactions is therefore essential.A compartmental framework incorporating tsetse flies,humans,cattle,wildlife and various disease control strategies is developed and analyzed.The reproduction is derived and its sensitivity to different model parameters is investigated.Meanwhile,the optimal control theory is used to identify a combination of control strategies capable of minimizing the infected human and cattle population over time at minimal costs of implementation.The results indicates that tsetse fly mortality rate is strongly and negatively correlated to the reproduction number.It is also established that tsetse fly feeding rate in strongly and positively correlated to the reproduction number.Simulation results indicates that time dependent control strategies can significantly reduce the infections.Overall,the study shows that screening and treatment of humans may not lead to disease elimination.Combining this strategy with other strategies such as screening and treatment of cattle and vector control strategies will result in maximum reduction of tsetse fly population and disease elimination. 展开更多
关键词 Human African trypanosomiasis mathematical model Intervention strategies Optimal control theory
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Exploration of the Application of Information Technology in Mathematics Curriculum
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作者 Qing Zhang 《Journal of Contemporary Educational Research》 2025年第11期221-226,共6页
Mathematics is a basic course for cultivating advanced technical talents,a core course for students in the basic education stage,mathematical knowledge content is the foundation of professional courses,mathematical th... Mathematics is a basic course for cultivating advanced technical talents,a core course for students in the basic education stage,mathematical knowledge content is the foundation of professional courses,mathematical thinking ability is one of the abilities for students’sustainable development,mathematical literacy is a basic quality that students should possess,and it carries the function of implementing the fundamental task of fostering virtue and nurturing talent and developing quality-oriented education.It has the characteristics of being fundamental,developmental,applied,and vocational.In today’s era of rapid development of artificial intelligence and big data,mathematics plays a huge role in production and life.This paper briefly expounds and analyzes the current situation of mathematics teaching,explores the significance of information-based teaching for mathematics teaching,and on this basis,proposes relevant strategies for information-based mathematics teaching,including knowledge visualization,the use of information technology to create mathematics teaching scenarios,the realization of efficient mathematics teaching through micro-lessons,and the realization of teaching interaction through network platforms. 展开更多
关键词 Information-based teaching mathematics teaching Teaching effectiveness
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