Assessment of imprecise time-variant reliability in engineering is a critical task when accounting for both the variability of structural properties and loads over time and the presence of uncertainties involved in th...Assessment of imprecise time-variant reliability in engineering is a critical task when accounting for both the variability of structural properties and loads over time and the presence of uncertainties involved in the ambiguity of parameters simultaneously.To estimate the Imprecise Time-variant Failure Probability Function(ITFPF)and derive the imprecise reliability results as a byproduct,Adaptive Combination Augmented Line Sampling(ACALS)is proposed.It consists of three integrated features:Augmented Line Sampling(ALS),adaptive strategy,and the optimal combination.ALS is adopted as an efficient analysis tool to obtain the failure probability function w.r.t.imprecise parameters.Then,the adaptive strategy iteratively applies ALS while considering both imprecise parameters and time simultaneously.Finally,the optimal combination algorithm collects all result components in an optimal manner to minimize the Coefficient of Variance(C.o.V.)of the ITFPF estimate.Overall,the proposed ACALS method outperforms the original ALS method by efficiently estimating the ITFPF while guaranteeing a minimal C.o.V.Thus,the proposed approach can serve as an effective tool for imprecise time-variant reliability analysis in real engineering applications.Several examples are presented to demonstrate the superiority of the proposed approach in addressing the challenges of estimating the ITFPF.展开更多
To reduce the cost and increase the efficiency of plant genetic marker fingerprinting for variety discrimination,it is desirable to identify the optimal marker combinations.We describe a marker combination screening m...To reduce the cost and increase the efficiency of plant genetic marker fingerprinting for variety discrimination,it is desirable to identify the optimal marker combinations.We describe a marker combination screening model based on the genetic algorithm(GA)and implemented in a software tool,Loci Scan.Ratio-based variety discrimination power provided the largest optimization space among multiple fitness functions.Among GA parameters,an increase in population size and generation number enlarged optimization depth but also calculation workload.Exhaustive algorithm afforded the same optimization depth as GA but vastly increased calculation time.In comparison with two other software tools,Loci Scan accommodated missing data,reduced calculation time,and offered more fitness functions.In large datasets,the sample size of training data exerted the strongest influence on calculation time,whereas the marker size of training data showed no effect,and target marker number had limited effect on analysis speed.展开更多
Precise and timely prediction of crop yields is crucial for food security and the development of agricultural policies.However,crop yield is influenced by multiple factors within complex growth environments.Previous r...Precise and timely prediction of crop yields is crucial for food security and the development of agricultural policies.However,crop yield is influenced by multiple factors within complex growth environments.Previous research has paid relatively little attention to the interference of environmental factors and drought on the growth of winter wheat.Therefore,there is an urgent need for more effective methods to explore the inherent relationship between these factors and crop yield,making precise yield prediction increasingly important.This study was based on four type of indicators including meteorological,crop growth status,environmental,and drought index,from October 2003 to June 2019 in Henan Province as the basic data for predicting winter wheat yield.Using the sparrow search al-gorithm combined with random forest(SSA-RF)under different input indicators,accuracy of winter wheat yield estimation was calcu-lated.The estimation accuracy of SSA-RF was compared with partial least squares regression(PLSR),extreme gradient boosting(XG-Boost),and random forest(RF)models.Finally,the determined optimal yield estimation method was used to predict winter wheat yield in three typical years.Following are the findings:1)the SSA-RF demonstrates superior performance in estimating winter wheat yield compared to other algorithms.The best yield estimation method is achieved by four types indicators’composition with SSA-RF)(R^(2)=0.805,RRMSE=9.9%.2)Crops growth status and environmental indicators play significant roles in wheat yield estimation,accounting for 46%and 22%of the yield importance among all indicators,respectively.3)Selecting indicators from October to April of the follow-ing year yielded the highest accuracy in winter wheat yield estimation,with an R^(2)of 0.826 and an RMSE of 9.0%.Yield estimates can be completed two months before the winter wheat harvest in June.4)The predicted performance will be slightly affected by severe drought.Compared with severe drought year(2011)(R^(2)=0.680)and normal year(2017)(R^(2)=0.790),the SSA-RF model has higher prediction accuracy for wet year(2018)(R^(2)=0.820).This study could provide an innovative approach for remote sensing estimation of winter wheat yield.yield.展开更多
The alternate combinational approach of genetic algorithm and neural network （AGANN） has been presented to correct the systematic error of the density functional theory （DFT） calculation. It treats the DFT as a bl...The alternate combinational approach of genetic algorithm and neural network （AGANN） has been presented to correct the systematic error of the density functional theory （DFT） calculation. It treats the DFT as a black box and models the error through external statistical information. As a demonstration, the ACANN method has been applied in the correction of the lattice energies from the DFT calculation for 72 metal halides and hydrides. Through the AGANN correction, the mean absolute value of the relative errors of the calculated lattice energies to the experimental values decreases from 4.93% to 1.20% in the testing set. For comparison, the neural network approach reduces the mean value to 2.56%. And for the common combinational approach of genetic algorithm and neural network, the value drops to 2.15%. The multiple linear regression method almost has no correction effect here.展开更多
High-precision methane gas detection is of great importance in industrial safety, energy production and environmental protection, etc. However, in the existing measurement techniques, the methane gas concentration inf...High-precision methane gas detection is of great importance in industrial safety, energy production and environmental protection, etc. However, in the existing measurement techniques, the methane gas concentration information is susceptible to noise, which leads to its useful signal being drowned by noise. A fusion algorithm of variational modal decomposition(VMD) and improved wavelet threshold filtering is proposed, which is used in combination with tunable diode laser absorption spectroscopy(TDLAS) to implement a non-contact, high-resolution methane gas concentration detection. The fusion algorithm can perform noise reduction and further segmentation of the methane gas detection signal. And the simulation and experiment verify the effectiveness of the fusion algorithm, and the experimental results show that for the detection of air containing 10 ppm, 30 ppm, 60 ppm, 80 ppm, and 99 ppm methane, the errors are 12.75%, 8.18%, 3.37%, 2.46%, and 1.78%, respectively.展开更多
Combined Heat and Power Economic Dispatch(CHPED)is an important problem in the energy field,and it is beneficial for improving the utilization efficiency of power and heat energies.This paper proposes a Modified Genet...Combined Heat and Power Economic Dispatch(CHPED)is an important problem in the energy field,and it is beneficial for improving the utilization efficiency of power and heat energies.This paper proposes a Modified Genetic Algorithm(MGA)to determine the power and heat outputs of three kinds of units for CHPED.First,MGA replaces the simulated binary crossover by a new one based on the uniform and guassian distributions,and its convergence can be enhanced.Second,MGA modi-fies the mutation operator by introducing a disturbance coefficient based on guassian distribution,which can decrease the risk of being trapped into local optima.Eight instances with or without prohibited operating zones are used to investigate the efficiencies of MGA and other four genetic algorithms for CHPED.In comparison with the other algorithms,MGA has reduced generation costs by at least 562.73$,1068.7$,522.68$and 1016.24$,respectively,for instances 3,4,7 and 8,and it has reduced generation costs by at most 848.22$,3642.85$,897.63$and 3812.65$,respectively,for instances 3,4,7 and 8.Therefore,MGA has desirable convergence and stability for CHPED in comparison with the other four genetic algorithms.展开更多
The accurate identification of the oil-paper insulation state of a transformer is crucial for most maintenance strategies.This paper presents a multi-feature comprehensive evaluation model based on combination weighti...The accurate identification of the oil-paper insulation state of a transformer is crucial for most maintenance strategies.This paper presents a multi-feature comprehensive evaluation model based on combination weighting and an improved technique for order of preference by similarity to ideal solution(TOPSIS)method to perform an objective and scientific evaluation of the transformer oil-paper insulation state.Firstly,multiple aging features are extracted from the recovery voltage polarization spectrum and the extended Debye equivalent circuit owing to the limitations of using a single feature for evaluation.A standard evaluation index system is then established by using the collected time-domain dielectric spectrum data.Secondly,this study implements the per-unit value concept to integrate the dimension of the index matrix and calculates the objective weight by using the random forest algorithm.Furthermore,it combines the weighting model to overcome the drawbacks of the single weighting method by using the indicators and considering the subjective experience of experts and the random forest algorithm.Lastly,the enhanced TOPSIS approach is used to determine the insulation quality of an oil-paper transformer.A verification example demonstrates that the evaluation model developed in this study can efficiently and accurately diagnose the insulation status of transformers.Essentially,this study presents a novel approach for the assessment of transformer oil-paper insulation.展开更多
Task scheduling for electro-magnetic detection satellite is a typical combinatorial optimization problem. The count of constraints that need to be taken into account is of large scale. An algorithm combined integer pr...Task scheduling for electro-magnetic detection satellite is a typical combinatorial optimization problem. The count of constraints that need to be taken into account is of large scale. An algorithm combined integer programming with constraint programming is presented. This algorithm is deployed in this problem through two steps. The first step is to decompose the original problem into master and sub-problem using the logic-based Benders decomposition; then a circus combines master and sub-problem solving process together, and the connection between them is general Benders cut. This hybrid algorithm is tested by a set of derived experiments. The result is compared with corresponding outcomes generated by the strength Pareto evolutionary algorithm and the pure constraint programming solver GECODE, which is an open source software. These tests and comparisons yield promising effect.展开更多
This paper presents the solution to the combined heat and power economic dispatch problem using a direct solution algorithm for constrained optimization problems. With the potential of Combined Heat and Power (CHP) pr...This paper presents the solution to the combined heat and power economic dispatch problem using a direct solution algorithm for constrained optimization problems. With the potential of Combined Heat and Power (CHP) production to increase the efficiency of power and heat generation simultaneously having been researched and established, the increasing penetration of CHP systems, and determination of economic dispatch of power and heat assumes higher relevance. The Combined Heat and Power Economic Dispatch (CHPED) problem is a demanding optimization problem as both constraints and objective functions can be non-linear and non-convex. This paper presents an explicit formula developed for computing the system-wide incremental costs corresponding with optimal dispatch. The circumvention of the use of iterative search schemes for this crucial step is the innovation inherent in the proposed dispatch procedure. The feasible operating region of the CHP unit three is taken into account in the proposed CHPED problem model, whereas the optimal dispatch of power/heat outputs of CHP unit is determined using the direct Lagrange multiplier solution algorithm. The proposed algorithm is applied to a test system with four units and results are provided.展开更多
Cancer staging detection is important for clinician to assess the patients' status and make optimal therapy decision. In this study, the machine learning algorithm based on principal component analysis(PCA) and su...Cancer staging detection is important for clinician to assess the patients' status and make optimal therapy decision. In this study, the machine learning algorithm based on principal component analysis(PCA) and support vector machine(SVM) was combined with urine surface-enhanced Raman scattering(SERS) spectroscopy for improving the identification of colorectal cancer(CRC) at early and advanced stages. Two discriminant methods, linear discriminant analysis(LDA) and SVM were compared, and the results indicated that the diagnostic accuracy of SVM(93.65%) was superior to that of LDA(80.95%). This exploratory study demonstrated the great promise of urine SERS spectra along with PCA-SVM for facilitating more accurate detection of CRC at different stages.展开更多
Korean characters consist of 2 dimensional distributed consonantal and vowel graphemes. The purpose of reducing the 2 dimensional characteristics of Korean characters to linear arrangements at early stage of character...Korean characters consist of 2 dimensional distributed consonantal and vowel graphemes. The purpose of reducing the 2 dimensional characteristics of Korean characters to linear arrangements at early stage of character recognition is to decrease the complexity of following recognition task. By defining the identification codes for the vowel graphemes of Korean characters, the rules for combination of vowel graphemes are established, and a recognition algorithm based on the rules for combination of vowel graphemes, is therefore proposed for vertical vowel graphemes. The algorithm has been proved feasilbe through demonstrating simulations.展开更多
Scheduling chain combination is the core of chain-based scheduling algorithms, the speed of which determines the overall performance of corresponding scheduling algorithm. However, backtracking is used in general comb...Scheduling chain combination is the core of chain-based scheduling algorithms, the speed of which determines the overall performance of corresponding scheduling algorithm. However, backtracking is used in general combination algorithms to traverse the whole search space which may introduce redundant operations, so performance of the combination algorithm is generally poor. A fast scheduling chain combination algorithm which avoids redundant operations by skipping “incompatible” steps of scheduling chains and using a stack to remember the scheduling state is presented in this paper to overcome the problem. Experimental results showed that it can improve the performance of scheduling algorithms by up to 15 times. By further omitting unnecessary operations, a fast algorithm of minimum combination length prediction is developed, which can improve the speed by up to 10 times.展开更多
A new method for power quality (PQ) disturbances identification is brought forward based on combining a neural network with least square (LS) weighted fusion algorithm. The characteristic components of PQ disturbances...A new method for power quality (PQ) disturbances identification is brought forward based on combining a neural network with least square (LS) weighted fusion algorithm. The characteristic components of PQ disturbances are distilled through an improved phase-located loop (PLL) system at first, and then five child BP ANNs with different structures are trained and adopted to identify the PQ disturbances respectively. The combining neural network fuses the identification results of these child ANNs with LS weighted fusion algorithm, and identifies PQ disturbances with the fused result finally. Compared with a single neural network, the combining one with LS weighted fusion algorithm can identify the PQ disturbances correctly when noise is strong. However, a single neural network may fail in this case. Furthermore, the combining neural network is more reliable than a single neural network. The simulation results prove the conclusions above.展开更多
Objective:This paper discusses the composition of prescription qualitative,quantitative design principles and methods based on herbal property combination,describing the method application in new prescription design.M...Objective:This paper discusses the composition of prescription qualitative,quantitative design principles and methods based on herbal property combination,describing the method application in new prescription design.Method:Qualitative property-combination pattern(PP)calculation was based on bipartite graphing and performing a greedy algorithm which was designed to optimize obtaining a new herbal prescription.Quantitative PP calculation was based on the qualitative computation.To calculate the Euclidean distance for the PP of the new prescription,an optimized algorithm for solving the unknown minimum Euclidean distance was used with,the new weighted proportions.Finally,non-linear optimization software was used to find the minimum Euclidean distance.Results:Using the PP of classic prescription Large Yin-Nourishing Pill,applying quantitative PP calculation a new prescription was created.Mathematical algorithms based on property combinations of traditional Chinese herbs can be applied to identify compatibility and synergies of herbs within prescriptions,especially classic formulas.Conclusion:In silico methods can then be used to create new prescriptions or modify existing ones depending on need.This type of automated approach may increase efficiency in designing new drugs based on Chinese herbs.展开更多
基金The Aeronautical Science Foundation of China(Nos.20170968002,20230003068002)The National Major Science and Technology Projects of China(Nos.J2019-II-0022-0043,J2019-VII-0013-0153).
文摘Assessment of imprecise time-variant reliability in engineering is a critical task when accounting for both the variability of structural properties and loads over time and the presence of uncertainties involved in the ambiguity of parameters simultaneously.To estimate the Imprecise Time-variant Failure Probability Function(ITFPF)and derive the imprecise reliability results as a byproduct,Adaptive Combination Augmented Line Sampling(ACALS)is proposed.It consists of three integrated features:Augmented Line Sampling(ALS),adaptive strategy,and the optimal combination.ALS is adopted as an efficient analysis tool to obtain the failure probability function w.r.t.imprecise parameters.Then,the adaptive strategy iteratively applies ALS while considering both imprecise parameters and time simultaneously.Finally,the optimal combination algorithm collects all result components in an optimal manner to minimize the Coefficient of Variance(C.o.V.)of the ITFPF estimate.Overall,the proposed ACALS method outperforms the original ALS method by efficiently estimating the ITFPF while guaranteeing a minimal C.o.V.Thus,the proposed approach can serve as an effective tool for imprecise time-variant reliability analysis in real engineering applications.Several examples are presented to demonstrate the superiority of the proposed approach in addressing the challenges of estimating the ITFPF.
基金supported by the Scientific and Technological Innovation 2030 Major Project(2022ZD04019)the Science and Technology Innovation Capacity Building Project of BAAFS(KJCX20230303)+1 种基金Hainan Province Science and Technology Special Fund(ZDYF2023XDNY077)the Beijing Scholars Program(BSP041)。
文摘To reduce the cost and increase the efficiency of plant genetic marker fingerprinting for variety discrimination,it is desirable to identify the optimal marker combinations.We describe a marker combination screening model based on the genetic algorithm(GA)and implemented in a software tool,Loci Scan.Ratio-based variety discrimination power provided the largest optimization space among multiple fitness functions.Among GA parameters,an increase in population size and generation number enlarged optimization depth but also calculation workload.Exhaustive algorithm afforded the same optimization depth as GA but vastly increased calculation time.In comparison with two other software tools,Loci Scan accommodated missing data,reduced calculation time,and offered more fitness functions.In large datasets,the sample size of training data exerted the strongest influence on calculation time,whereas the marker size of training data showed no effect,and target marker number had limited effect on analysis speed.
基金Under the auspices of National Natural Science Foundation of China(No.52079103)。
文摘Precise and timely prediction of crop yields is crucial for food security and the development of agricultural policies.However,crop yield is influenced by multiple factors within complex growth environments.Previous research has paid relatively little attention to the interference of environmental factors and drought on the growth of winter wheat.Therefore,there is an urgent need for more effective methods to explore the inherent relationship between these factors and crop yield,making precise yield prediction increasingly important.This study was based on four type of indicators including meteorological,crop growth status,environmental,and drought index,from October 2003 to June 2019 in Henan Province as the basic data for predicting winter wheat yield.Using the sparrow search al-gorithm combined with random forest(SSA-RF)under different input indicators,accuracy of winter wheat yield estimation was calcu-lated.The estimation accuracy of SSA-RF was compared with partial least squares regression(PLSR),extreme gradient boosting(XG-Boost),and random forest(RF)models.Finally,the determined optimal yield estimation method was used to predict winter wheat yield in three typical years.Following are the findings:1)the SSA-RF demonstrates superior performance in estimating winter wheat yield compared to other algorithms.The best yield estimation method is achieved by four types indicators’composition with SSA-RF)(R^(2)=0.805,RRMSE=9.9%.2)Crops growth status and environmental indicators play significant roles in wheat yield estimation,accounting for 46%and 22%of the yield importance among all indicators,respectively.3)Selecting indicators from October to April of the follow-ing year yielded the highest accuracy in winter wheat yield estimation,with an R^(2)of 0.826 and an RMSE of 9.0%.Yield estimates can be completed two months before the winter wheat harvest in June.4)The predicted performance will be slightly affected by severe drought.Compared with severe drought year(2011)(R^(2)=0.680)and normal year(2017)(R^(2)=0.790),the SSA-RF model has higher prediction accuracy for wet year(2018)(R^(2)=0.820).This study could provide an innovative approach for remote sensing estimation of winter wheat yield.yield.
基金supported by the National Basic Research Program of China (973 Program) (Grant No. G2009CB929300)the National Natural Science Foundation of China (Grant No. 60521001 and 60925016)
文摘The alternate combinational approach of genetic algorithm and neural network （AGANN） has been presented to correct the systematic error of the density functional theory （DFT） calculation. It treats the DFT as a black box and models the error through external statistical information. As a demonstration, the ACANN method has been applied in the correction of the lattice energies from the DFT calculation for 72 metal halides and hydrides. Through the AGANN correction, the mean absolute value of the relative errors of the calculated lattice energies to the experimental values decreases from 4.93% to 1.20% in the testing set. For comparison, the neural network approach reduces the mean value to 2.56%. And for the common combinational approach of genetic algorithm and neural network, the value drops to 2.15%. The multiple linear regression method almost has no correction effect here.
基金supported by the Project Grant from Heilongjiang Bayi Agricultural Reclamation University,Heilongjiang,China (No.XDB201813)。
文摘High-precision methane gas detection is of great importance in industrial safety, energy production and environmental protection, etc. However, in the existing measurement techniques, the methane gas concentration information is susceptible to noise, which leads to its useful signal being drowned by noise. A fusion algorithm of variational modal decomposition(VMD) and improved wavelet threshold filtering is proposed, which is used in combination with tunable diode laser absorption spectroscopy(TDLAS) to implement a non-contact, high-resolution methane gas concentration detection. The fusion algorithm can perform noise reduction and further segmentation of the methane gas detection signal. And the simulation and experiment verify the effectiveness of the fusion algorithm, and the experimental results show that for the detection of air containing 10 ppm, 30 ppm, 60 ppm, 80 ppm, and 99 ppm methane, the errors are 12.75%, 8.18%, 3.37%, 2.46%, and 1.78%, respectively.
基金supported by the National Natural Science Foundation of China(NSFC)under Grant 61873272,62073327in part by the Natural Science Foundation of Jiangsu Province under Grant BK20200086,BK20200631.
文摘Combined Heat and Power Economic Dispatch(CHPED)is an important problem in the energy field,and it is beneficial for improving the utilization efficiency of power and heat energies.This paper proposes a Modified Genetic Algorithm(MGA)to determine the power and heat outputs of three kinds of units for CHPED.First,MGA replaces the simulated binary crossover by a new one based on the uniform and guassian distributions,and its convergence can be enhanced.Second,MGA modi-fies the mutation operator by introducing a disturbance coefficient based on guassian distribution,which can decrease the risk of being trapped into local optima.Eight instances with or without prohibited operating zones are used to investigate the efficiencies of MGA and other four genetic algorithms for CHPED.In comparison with the other algorithms,MGA has reduced generation costs by at least 562.73$,1068.7$,522.68$and 1016.24$,respectively,for instances 3,4,7 and 8,and it has reduced generation costs by at most 848.22$,3642.85$,897.63$and 3812.65$,respectively,for instances 3,4,7 and 8.Therefore,MGA has desirable convergence and stability for CHPED in comparison with the other four genetic algorithms.
基金supported by the Natural Science Foundation of the Fujian Province(2021J01109).
文摘The accurate identification of the oil-paper insulation state of a transformer is crucial for most maintenance strategies.This paper presents a multi-feature comprehensive evaluation model based on combination weighting and an improved technique for order of preference by similarity to ideal solution(TOPSIS)method to perform an objective and scientific evaluation of the transformer oil-paper insulation state.Firstly,multiple aging features are extracted from the recovery voltage polarization spectrum and the extended Debye equivalent circuit owing to the limitations of using a single feature for evaluation.A standard evaluation index system is then established by using the collected time-domain dielectric spectrum data.Secondly,this study implements the per-unit value concept to integrate the dimension of the index matrix and calculates the objective weight by using the random forest algorithm.Furthermore,it combines the weighting model to overcome the drawbacks of the single weighting method by using the indicators and considering the subjective experience of experts and the random forest algorithm.Lastly,the enhanced TOPSIS approach is used to determine the insulation quality of an oil-paper transformer.A verification example demonstrates that the evaluation model developed in this study can efficiently and accurately diagnose the insulation status of transformers.Essentially,this study presents a novel approach for the assessment of transformer oil-paper insulation.
基金supported by the National Security Fundamental Research Foundation of China (61361)the National Natural Science Foundation of China (61104180)
文摘Task scheduling for electro-magnetic detection satellite is a typical combinatorial optimization problem. The count of constraints that need to be taken into account is of large scale. An algorithm combined integer programming with constraint programming is presented. This algorithm is deployed in this problem through two steps. The first step is to decompose the original problem into master and sub-problem using the logic-based Benders decomposition; then a circus combines master and sub-problem solving process together, and the connection between them is general Benders cut. This hybrid algorithm is tested by a set of derived experiments. The result is compared with corresponding outcomes generated by the strength Pareto evolutionary algorithm and the pure constraint programming solver GECODE, which is an open source software. These tests and comparisons yield promising effect.
文摘This paper presents the solution to the combined heat and power economic dispatch problem using a direct solution algorithm for constrained optimization problems. With the potential of Combined Heat and Power (CHP) production to increase the efficiency of power and heat generation simultaneously having been researched and established, the increasing penetration of CHP systems, and determination of economic dispatch of power and heat assumes higher relevance. The Combined Heat and Power Economic Dispatch (CHPED) problem is a demanding optimization problem as both constraints and objective functions can be non-linear and non-convex. This paper presents an explicit formula developed for computing the system-wide incremental costs corresponding with optimal dispatch. The circumvention of the use of iterative search schemes for this crucial step is the innovation inherent in the proposed dispatch procedure. The feasible operating region of the CHP unit three is taken into account in the proposed CHPED problem model, whereas the optimal dispatch of power/heat outputs of CHP unit is determined using the direct Lagrange multiplier solution algorithm. The proposed algorithm is applied to a test system with four units and results are provided.
基金supported by the National Natural Science Foundation of China (No.61975031)the Natural Science Foundation of Fujian Province (No.2020J011121)+3 种基金the Product-University Cooperation Project of Fujian Province (No.2020Y4006)the National Clinical Key Specialty Construction Program (No.2021)the Fujian Provincial Clinical Research Center for Cancer Radiotherapy and Immunotherapy (No.2020Y2012)the Joint Funds for the Innovation of Science and Technology of Fujian Province (No.2021Y9192)。
文摘Cancer staging detection is important for clinician to assess the patients' status and make optimal therapy decision. In this study, the machine learning algorithm based on principal component analysis(PCA) and support vector machine(SVM) was combined with urine surface-enhanced Raman scattering(SERS) spectroscopy for improving the identification of colorectal cancer(CRC) at early and advanced stages. Two discriminant methods, linear discriminant analysis(LDA) and SVM were compared, and the results indicated that the diagnostic accuracy of SVM(93.65%) was superior to that of LDA(80.95%). This exploratory study demonstrated the great promise of urine SERS spectra along with PCA-SVM for facilitating more accurate detection of CRC at different stages.
文摘Korean characters consist of 2 dimensional distributed consonantal and vowel graphemes. The purpose of reducing the 2 dimensional characteristics of Korean characters to linear arrangements at early stage of character recognition is to decrease the complexity of following recognition task. By defining the identification codes for the vowel graphemes of Korean characters, the rules for combination of vowel graphemes are established, and a recognition algorithm based on the rules for combination of vowel graphemes, is therefore proposed for vertical vowel graphemes. The algorithm has been proved feasilbe through demonstrating simulations.
基金Project (No. Y105355) supported by the Natural Science Foundationof Zhejiang Province, China
文摘Scheduling chain combination is the core of chain-based scheduling algorithms, the speed of which determines the overall performance of corresponding scheduling algorithm. However, backtracking is used in general combination algorithms to traverse the whole search space which may introduce redundant operations, so performance of the combination algorithm is generally poor. A fast scheduling chain combination algorithm which avoids redundant operations by skipping “incompatible” steps of scheduling chains and using a stack to remember the scheduling state is presented in this paper to overcome the problem. Experimental results showed that it can improve the performance of scheduling algorithms by up to 15 times. By further omitting unnecessary operations, a fast algorithm of minimum combination length prediction is developed, which can improve the speed by up to 10 times.
基金Sponsored by the Teaching and Research Award Programfor Outstanding Young Teachers in High Education Institutions of MOE China(Grant No.ZDXM03006).
文摘A new method for power quality (PQ) disturbances identification is brought forward based on combining a neural network with least square (LS) weighted fusion algorithm. The characteristic components of PQ disturbances are distilled through an improved phase-located loop (PLL) system at first, and then five child BP ANNs with different structures are trained and adopted to identify the PQ disturbances respectively. The combining neural network fuses the identification results of these child ANNs with LS weighted fusion algorithm, and identifies PQ disturbances with the fused result finally. Compared with a single neural network, the combining one with LS weighted fusion algorithm can identify the PQ disturbances correctly when noise is strong. However, a single neural network may fail in this case. Furthermore, the combining neural network is more reliable than a single neural network. The simulation results prove the conclusions above.
基金The authors gratefully acknowledge the support of this work by the National Natural Science Foundation of China(No.81430094,81173568,81373985).
文摘Objective:This paper discusses the composition of prescription qualitative,quantitative design principles and methods based on herbal property combination,describing the method application in new prescription design.Method:Qualitative property-combination pattern(PP)calculation was based on bipartite graphing and performing a greedy algorithm which was designed to optimize obtaining a new herbal prescription.Quantitative PP calculation was based on the qualitative computation.To calculate the Euclidean distance for the PP of the new prescription,an optimized algorithm for solving the unknown minimum Euclidean distance was used with,the new weighted proportions.Finally,non-linear optimization software was used to find the minimum Euclidean distance.Results:Using the PP of classic prescription Large Yin-Nourishing Pill,applying quantitative PP calculation a new prescription was created.Mathematical algorithms based on property combinations of traditional Chinese herbs can be applied to identify compatibility and synergies of herbs within prescriptions,especially classic formulas.Conclusion:In silico methods can then be used to create new prescriptions or modify existing ones depending on need.This type of automated approach may increase efficiency in designing new drugs based on Chinese herbs.
