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Interactive Dynamic Graph Convolution with Temporal Attention for Traffic Flow Forecasting
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作者 Zitong Zhao Zixuan Zhang Zhenxing Niu 《Computers, Materials & Continua》 2026年第1期1049-1064,共16页
Reliable traffic flow prediction is crucial for mitigating urban congestion.This paper proposes Attentionbased spatiotemporal Interactive Dynamic Graph Convolutional Network(AIDGCN),a novel architecture integrating In... Reliable traffic flow prediction is crucial for mitigating urban congestion.This paper proposes Attentionbased spatiotemporal Interactive Dynamic Graph Convolutional Network(AIDGCN),a novel architecture integrating Interactive Dynamic Graph Convolution Network(IDGCN)with Temporal Multi-Head Trend-Aware Attention.Its core innovation lies in IDGCN,which uniquely splits sequences into symmetric intervals for interactive feature sharing via dynamic graphs,and a novel attention mechanism incorporating convolutional operations to capture essential local traffic trends—addressing a critical gap in standard attention for continuous data.For 15-and 60-min forecasting on METR-LA,AIDGCN achieves MAEs of 0.75%and 0.39%,and RMSEs of 1.32%and 0.14%,respectively.In the 60-min long-term forecasting of the PEMS-BAY dataset,the AIDGCN out-performs the MRA-BGCN method by 6.28%,4.93%,and 7.17%in terms of MAE,RMSE,and MAPE,respectively.Experimental results demonstrate the superiority of our pro-posed model over state-of-the-art methods. 展开更多
关键词 Traffic flow prediction interactive dynamic graph convolution graph convolution temporal multi-head trend-aware attention self-attention mechanism
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Independent and interactive effects of N and P additions on foliar P fractions in evergreen forests of southern China 被引量:1
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作者 Qingquan Meng Zhijuan Shi +3 位作者 Zhengbing Yan Hans Lambers Yan Luo Wenxuan Han 《Forest Ecosystems》 2025年第1期66-73,共8页
Fertilization or atmospheric deposition of nitrogen(N)and phosphorus(P)to terrestrial ecosystems can alter soil N(P)availability and the nature of nutrient limitation for plant growth.Changing the allocation of leaf P... Fertilization or atmospheric deposition of nitrogen(N)and phosphorus(P)to terrestrial ecosystems can alter soil N(P)availability and the nature of nutrient limitation for plant growth.Changing the allocation of leaf P fractions is potentially an adaptive strategy for plants to cope with soil N(P)availability and nutrient-limiting conditions.However,the impact of the interactions between imbalanced anthropogenic N and P inputs on the concentrations and allocation proportions of leaf P fractions in forest woody plants remains elusive.We conducted a metaanalysis of data about the concentrations and allocation proportions of leaf P fractions,specifically associated with individual and combined additions of N and P in evergreen forests,the dominant vegetation type in southern China where the primary productivity is usually considered limited by P.This assessment allowed us to quantitatively evaluate the effects of N and P additions alone and interactively on leaf P allocation and use strategies.Nitrogen addition(exacerbating P limitation)reduced the concentrations of leaf total P and different leaf P fractions.Nitrogen addition reduced the allocation to leaf metabolic P but increased the allocation to other fractions,while P addition showed opposite trends.The simultaneous additions of N and P showed an antagonistic(mutual suppression)effect on the concentrations of leaf P fractions,but an additive(summary)effect on the allocation proportions of leaf P fractions.These results highlight the importance of strategies of leaf P fraction allocation in forest plants under changes in environmental nutrient availability.Importantly,our study identified critical interactions associated with combined N and P inputs that affect leaf P fractions,thus aiding in predicting plant acclimation strategies in the context of intensifying and imbalanced anthropogenic nutrient inputs. 展开更多
关键词 Anthropogenic nutrient inputs Individual and combined effects interactive effects Leaf phosphorus fractions Nitrogen and phosphorus additions Nutrient-utilization strategies Woody plants
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Uncovering differences in the spatial structure of intercity interactive networks described by multi-source migration flow:From the multi-hierarchical perspective
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作者 WEI Shimei PAN Jinghu 《Journal of Geographical Sciences》 2025年第5期1049-1079,共31页
Population migration data derived from location-based services has often been used to delineate population flows between cities or construct intercity relationship networks to reveal and explore the complex interactio... Population migration data derived from location-based services has often been used to delineate population flows between cities or construct intercity relationship networks to reveal and explore the complex interaction patterns underlying human activities.Nevertheless,the inherent heterogeneity in multimodal migration big data has been ignored.This study conducts an in-depth comparison and quantitative analysis through a comprehensive lens of spatial association.Initially,the intercity interactive networks in China were constructed,utilizing migration data from Baidu and AutoNavi collected during the same time period.Subsequently,the characteristics and spatial structure similarities of the two types of intercity interactive networks were quantitatively assessed and analyzed from overall(network)and local(node)perspectives.Furthermore,the precision of these networks at the local scale is corroborated by constructing an intercity network from mobile phone(MP)data.Results indicate that the intercity interactive networks in China,as delineated by Baidu and AutoNavi migration flows,exhibit a high degree of structure equivalence.The correlation coefficient between these two networks is 0.874.Both networks exhibit a pronounced spatial polarization trend and hierarchical structure.This is evident in their distinct core and peripheral structures,as well as in the varying importance and influence of different nodes within the networks.Nevertheless,there are notable differences worthy of attention.Baidu intercity interactive network exhibits pronounced cross-regional effects,and its high-level interactions are characterized by a“rich-club”phenomenon.The AutoNavi intercity interactive network presents a more significant distance attenuation effect,and the high-level interactions display a gradient distribution pattern.Notably,there exists a substantial correlation between the AutoNavi and MP networks at the local scale,evidenced by a high correlation coefficient of 0.954.Furthermore,the“spatial dislocations”phenomenon was observed within the spatial structures at different levels,extracted from the Baidu and AutoNavi intercity networks.However,the measured results of network spatial structure similarity from three dimensions,namely,node location,node size,and local structure,indicate a relatively high similarity and consistency between the two networks. 展开更多
关键词 network differences interactive network intercity migration multimodal data China
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Modeling the Influencing Factors of EFL Learners’ Online Interactive Learning: A Grounded Theory Approach
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作者 Guihua Ma 《Chinese Journal of Applied Linguistics》 2025年第3期401-424,481,共25页
Online interactive learning plays a crucial role in improving online education quality.This grounded theory study examines:(1)what key factors shape EFL learners’online interactive learning,(2)how these factors form ... Online interactive learning plays a crucial role in improving online education quality.This grounded theory study examines:(1)what key factors shape EFL learners’online interactive learning,(2)how these factors form an empirically validated model,and(3)how they interact within this model,through systematic analysis of 9,207 discussion forum posts from a Chinese University MOOC platform.Results demonstrate that learning drive,course structure,teaching competence,interaction behavior,expected outcomes,and online learning context significantly influence EFL online interactive learning.The analysis reveals two key mechanisms:expected outcomes mediate the effects of learning drive(β=0.45),course structure,teaching competence,and interaction behavior(β=0.35)on learning outcomes,while online learning context moderates these relationships(β=0.25).Specifically,learning drive provides intrinsic/extrinsic motivation,whereas course structure,teaching competence,interaction behavior,and expected outcomes collectively enhance interaction quality and sustainability.These findings,derived through rigorous grounded theory methodology involving open,axial,and selective coding of large-scale interaction data,yield three key contributions:(1)a comprehensive theoretical model of EFL online learning dynamics,(2)empirical validation of mediation/moderation mechanisms,and(3)practical strategies for designing scaffolded interaction protocols and adaptive feedback systems.The study establishes that its theoretically saturated model(achieved after analyzing 7,366 posts with 1,841 verification cases)offers educators evidence-based approaches to optimize collaborative interaction in digital EFL environments. 展开更多
关键词 online learning EFL learners interactive learning influencing factors grounded theory approach
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An intelligent drilling guide algorithm design framework based on highly interactive learning mechanism
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作者 Yi Zhao Dan-Dan Zhu +3 位作者 Fei Wang Xin-Ping Dai Hui-Shen Jiao Zi-Jie Zhou 《Petroleum Science》 2025年第8期3333-3343,共11页
Measurement-while-drilling(MWD)and guidance technologies have been extensively deployed in the exploitation of oil,natural gas,and other energy resources.Conventional control approaches are plagued by challenges,inclu... Measurement-while-drilling(MWD)and guidance technologies have been extensively deployed in the exploitation of oil,natural gas,and other energy resources.Conventional control approaches are plagued by challenges,including limited anti-interference capabilities and the insufficient generalization of decision-making experience.To address the intricate problem of directional well trajectory control,an intelligent algorithm design framework grounded in the high-level interaction mechanism between geology and engineering is put forward.This framework aims to facilitate the rapid batch migration and update of drilling strategies.The proposed directional well trajectory control method comprehensively considers the multi-source heterogeneous attributes of drilling experience data,leverages the generative simulation of the geological drilling environment,and promptly constructs a directional well trajectory control model with self-adaptive capabilities to environmental variations.This construction is carried out based on three hierarchical levels:“offline pre-drilling learning,online during-drilling interaction,and post-drilling model transfer”.Simulation results indicate that the guidance model derived from this method demonstrates remarkable generalization performance and accuracy.It can significantly boost the adaptability of the control algorithm to diverse environments and enhance the penetration rate of the target reservoir during drilling operations. 展开更多
关键词 Highly interactive decision algorithm Borehole guidance Intelligent control method Reinforcement learning Rapid perception Well drilling simulation
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Intelligent human-computer interactive training assistant system for rail systems
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作者 Yuexuan Li Junhua Chen +1 位作者 Xiangyong Luo Han Zheng 《High-Speed Railway》 2025年第1期64-77,共14页
In recent years,railway construction in China has developed vigorously.With continuous improvements in the highspeed railway network,the focus is gradually shifting from large-scale construction to large-scale operati... In recent years,railway construction in China has developed vigorously.With continuous improvements in the highspeed railway network,the focus is gradually shifting from large-scale construction to large-scale operations.However,several challenges have emerged within the high-speed railway dispatching and command system,including the heavy workload faced by dispatchers,the difficulty of quantifying subjective expertise,and the need for effective training of professionals.Amid the growing application of artificial intelligence technologies in railway systems,this study leverages Large Language Model(LLM)technology.LLMs bring enhanced intelligence,predictive capabilities,robust memory,and adaptability to diverse real-world scenarios.This study proposes a human-computer interactive intelligent scheduling auxiliary training system built on LLM technology.The system offers capabilities including natural dialogue,knowledge reasoning,and human feedback learning.With broad applicability,the system is suitable for vocational education,guided inquiry,knowledge-based Q&A,and other training scenarios.Validation results demonstrate its effectiveness in auxiliary training,providing substantial support for educators,students,and dispatching personnel in colleges and professional settings. 展开更多
关键词 High-speed railway Dispatch training assistance Large language model Human-computer interactive training assistant system Reinforcement learning
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Practical Application of the Multi-Dimensional Interactive Teaching Model in College English
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作者 Bo Sun 《Journal of Contemporary Educational Research》 2025年第10期106-111,共6页
The multi-dimensional interactive teaching model significantly enhances the effectiveness of college English instruction by emphasizing dynamic engagement between teachers and students,as well as among students themse... The multi-dimensional interactive teaching model significantly enhances the effectiveness of college English instruction by emphasizing dynamic engagement between teachers and students,as well as among students themselves.This paper explores practical strategies for implementing this model,focusing on four key aspects:deepening teachers’understanding of the model through continuous learning,innovating interactive methods such as questioning techniques and practical activities,leveraging modern technology to integrate resources and track learning progress,and establishing a communication platform that centers on student participation.By adopting these approaches,the model fosters a student-centered classroom environment,improves comprehensive English application skills,and optimizes overall teaching quality. 展开更多
关键词 Multi-dimensional interactive teaching model Student-centered approach Teacher-student interaction
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Telecontext-Enhanced Recursive Interactive Attention Fusion Method for Line-Level Defect Prediction
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作者 Haitao He Bingjian Yan +1 位作者 Ke Xu Lu Yu 《Computers, Materials & Continua》 2025年第2期2077-2108,共32页
Software defect prediction aims to use measurement data of code and historical defects to predict potential problems,optimize testing resources and defect management.However,current methods face challenges:(1)Coarse-g... Software defect prediction aims to use measurement data of code and historical defects to predict potential problems,optimize testing resources and defect management.However,current methods face challenges:(1)Coarse-grained file level detection cannot accurately locate specific defects.(2)Fine-grained line-level defect prediction methods rely solely on local information of a single line of code,failing to deeply analyze the semantic context of the code line and ignoring the heuristic impact of line-level context on the code line,making it difficult to capture the interaction between global and local information.Therefore,this paper proposes a telecontext-enhanced recursive interactive attention fusion method for line-level defect prediction(TRIA-LineDP).Firstly,using a bidirectional hierarchical attention network to extract semantic features and contextual information from the original code lines as the basis.Then,the extracted contextual information is forwarded to the telecontext capture module to aggregate the global context,thereby enhancing the understanding of broader code dynamics.Finally,a recursive interaction model is used to simulate the interaction between code lines and line-level context,passing information layer by layer to enhance local and global information exchange,thereby achieving accurate defect localization.Experimental results from within-project defect prediction(WPDP)and cross-project defect prediction(CPDP)conducted on nine different projects(encompassing a total of 32 versions)demonstrated that,within the same project,the proposed methods will respectively recall at top 20%of lines of code(Recall@Top20%LOC)and effort at top 20%recall(Effort@Top20%Recall)has increased by 11%–52%and 23%–77%.In different projects,improvements of 9%–60%and 18%–77%have been achieved,which are superior to existing advanced methods and have good detection performance. 展开更多
关键词 Line-level defect prediction telecontext capture recursive interactive structure hierarchical attention network
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Research on the Cultivation of College English Intercultural Communicative Competence under the Multimodal Interactive Teaching Mode
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作者 Hui Zhang 《Journal of Contemporary Educational Research》 2025年第1期123-128,共6页
With the development of globalization,intercultural communicative competence has become one of the core qualities of modern college students.As an important platform to cultivate students’language skills and cultural... With the development of globalization,intercultural communicative competence has become one of the core qualities of modern college students.As an important platform to cultivate students’language skills and cultural literacy,the innovation of college English teaching mode is essential.Based on this,this paper mainly discusses methods to effectively cultivate students’intercultural communicative competence in college English teaching from the perspective of multimodal interactive teaching mode,hoping to provide references for improving the quality of college English teaching and students’comprehensive quality. 展开更多
关键词 Multimodal interactive teaching mode College English Intercultural communicative competence Situational teaching
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Independent and Interactive Effects of Air Pollutants,Meteorological Factors,and Green Space on Tuberculosis Incidence in Shanghai
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作者 Qi Ye Jing Chen +10 位作者 Yating Ji Xiaoyu Lu Jiale Deng Nan Li Wei Wei Renjie Hou Zhiyuan Li Jianbang Xiang Xu Gao Xin Shen Chongguang Yang 《Biomedical and Environmental Sciences》 2025年第7期792-809,共18页
Objective To assess the independent and combined effects of air pollutants,meteorological factors,and greenspace exposure on new tuberculosis(TB)cases.Methods TB case data from Shanghai(2013–2018)were obtained from t... Objective To assess the independent and combined effects of air pollutants,meteorological factors,and greenspace exposure on new tuberculosis(TB)cases.Methods TB case data from Shanghai(2013–2018)were obtained from the Shanghai Center for Disease Control and Prevention.Environmental data on air pollutants,meteorological variables,and greenspace exposure were obtained from the National Tibetan Plateau Data Center.We employed a distributed-lag nonlinear model to assess the effects of these environmental factors on TB cases.Results Increased TB risk was linked to PM_(2.5),PM_(10),and rainfall,whereas NO_(2),SO_(2),and air pressure were associated with a reduced risk.Specifically,the strongest cumulative effects occurred at various lags:PM_(2.5)(RR=1.166,95%CI:1.026–1.325)at 0–19 weeks;PM_(10)(RR=1.167,95%CI:1.028–1.324)at 0–18 weeks;NO_(2)(RR=0.968,95%CI:0.938–0.999)at 0–1 weeks;SO_(2)(RR=0.945,95%CI:0.894–0.999)at 0–2 weeks;air pressure(RR=0.604,95%CI:0.447–0.816)at 0–8 weeks;and rainfall(RR=1.404,95%CI:1.076–1.833)at 0–22 weeks.Green space exposure did not significantly impact TB cases.Additionally,low temperatures amplified the effect of PM_(2.5)on TB.Conclusion Exposure to PM_(2.5),PM_(10),and rainfall increased the risk of TB,highlighting the need to address air pollutants for the prevention of TB in Shanghai. 展开更多
关键词 TUBERCULOSIS Air pollutant Meteorological factor Green space INTERACTION PM_(2.5)
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The Impact of Continuous Nursing Combined with KAP Intervention Guided by the Interactive Achievement Theory on Blood Glucose Control and Healthy Behaviors of Patients with Gestational Diabetes Mellitus
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作者 Yuan Yuan Chunyun Zhu 《Journal of Clinical and Nursing Research》 2025年第3期113-119,共7页
Objective:To analyze the nursing effect of implementing continuous nursing combined with knowledge,attitude,and practice(KAP)intervention under the guidance of interactive goal-setting theory for patients with gestati... Objective:To analyze the nursing effect of implementing continuous nursing combined with knowledge,attitude,and practice(KAP)intervention under the guidance of interactive goal-setting theory for patients with gestational diabetes mellitus(GDM).Methods:A total of 68 patients with GDM who were admitted to the hospital between December 2021 and December 2023 were selected and randomly divided into two groups using a random number table.The combined group(34 cases)received continuous nursing combined with KAP intervention under the premise of interactive goal-setting theory,while the conventional group(34 cases)received routine nursing care.Blood glucose control,health behavior scores,and other indicators were compared between the two groups.Results:After nursing,the blood glucose level in the combined group was lower than that in the conventional group,and the scores for health behavior and self-management ability were higher than those in the conventional group(P<0.05).Conclusion:Combined nursing can improve blood glucose control in patients with GDM,standardize their health behaviors,and cultivate their self-management skills. 展开更多
关键词 interactive goal-setting theory Continuous nursing Knowledge attitude and practice(KAP)intervention Gestational diabetes mellitus
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Research on the Interactive Design of Smart HomeInterface for the Elderly Based on QFD and HCI
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作者 Kun Wang Xuan Liu +2 位作者 Kexiang Li Zhuang Xiong Bingzhe Li 《Journal of Electronic Research and Application》 2025年第1期176-183,共8页
In an aging society,the interface design of smart home products is crucial to the quality of life of the elderly.This paper combines Quality Function Deployment(QFD)and Human-Computer Interaction(HCI)theories,taking s... In an aging society,the interface design of smart home products is crucial to the quality of life of the elderly.This paper combines Quality Function Deployment(QFD)and Human-Computer Interaction(HCI)theories,taking smart washing machines as an example,to explore new paths for the interface design of smart home products for the elderly.An interdisciplinary approach is adopted to construct a design process centered on elderly users,introduce the Kano model to classify requirements,realize the mapping and sorting of requirements to design parameters,and adopt the PUGH model for comprehensive evaluation.This study provides practical and theoretical support for the interface design of smart home products for the elderly. 展开更多
关键词 Smart home and aging Integration of QFD and HCI Interface interaction Design optimization
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葛洲坝库区裂隙河岸地表水地下水交互特征
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作者 文章 李一鸣 +3 位作者 郭绪磊 万坦 罗清树 周宏 《地学前缘》 北大核心 2026年第1期1-13,共13页
地表水地下水交互是流域水循环与物质迁移的关键过程,其机制取决于河岸带含水层结构与水动力特征的精细刻画。现有研究多聚焦于沉积河岸带,而岩溶裂隙河岸带因介质非均质性与流动路径复杂性,其交互机制仍存在认知空白。本研究以葛洲坝... 地表水地下水交互是流域水循环与物质迁移的关键过程,其机制取决于河岸带含水层结构与水动力特征的精细刻画。现有研究多聚焦于沉积河岸带,而岩溶裂隙河岸带因介质非均质性与流动路径复杂性,其交互机制仍存在认知空白。本研究以葛洲坝库区南岸典型裂隙河岸带为靶区,通过钻孔监测网络解析地下水对长江水位波动的响应模式,并构建三维基岩裂隙溶蚀宽大裂隙耦合数值模型,定量刻画双层裂隙含水系统的水量交换过程。主要结论如下:(1)研究区地下水赋存体系为双层裂隙含水层系统复合3条宽大裂隙密集带。地下水动态受长江水位的调控较为明显;(2)深层含水层排泄量大于浅层含水层;(3)宽大裂隙是地下水赋存迁移以及与长江进行水量交换的主要通道,其排泄量比基岩裂隙含水层高3个量级;(4)宽大裂隙是浅、深层裂隙含水层之间水量交换的主要通道。本研究定量刻画了裂隙河岸带双层裂隙岩溶耦合系统的交互通量与通道效应,为基岩区河岸带水资源精细管理和长江大保护提供了可直接落地的科学依据与技术范式。 展开更多
关键词 葛洲坝库区 地表水地下水交互 裂隙河岸带 数值模拟
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A Study on Alien Invasive Plants from the Interactive Mechanism between Species Niche and Material/Energy Flow 被引量:3
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作者 陈剑 喻庆国 杨宇明 《Agricultural Science & Technology》 CAS 2011年第1期14-19,共6页
[Objective]This study was to reveal the essence of mechanism about how the alien invasive plants spread.[Method]Species niche and material/energy flow were used as basic research indicators to analyze the intrinsic me... [Objective]This study was to reveal the essence of mechanism about how the alien invasive plants spread.[Method]Species niche and material/energy flow were used as basic research indicators to analyze the intrinsic mechanism of alien plants invasion.[Result]Most of the invasive plants have not been explicitly defined and their effective control methods not brought forward.[Conclusion]Overrun of alien invasive plants depends on whether the niche of a species could be continuously met at spatial level.Based on this we put forward corresponding control measures,proposed an assumption to establish a cylinder-network model and discussed the definition of alien invasive plants. 展开更多
关键词 Species niche Material/energy flow Alien invasive plants interactive mechanism
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An Exploration of the Interactive Web-based College English Teaching Model 被引量:1
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作者 周迎 《Sino-US English Teaching》 2006年第4期47-51,共5页
In the light of the theory of constructivism, the interactive web-based college English teaching model is intended to facilitate "autonomy", "inquiry" and "cooperation" in learning English. This paper presents a... In the light of the theory of constructivism, the interactive web-based college English teaching model is intended to facilitate "autonomy", "inquiry" and "cooperation" in learning English. This paper presents a research in which the interactive web-based college English teaching model intends to reshape the teacher's and learner's roles in the classroom. Based on the research, an exploration is made --- within the framework of the interactive web-based model --- on the design of "teaching model" and "learning model", its application and related potential problems. 展开更多
关键词 interactive web-based college English teaching model CONSTRUCTIVISM AUTONOMY inquiry cooperation
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Construction of crash prediction model of freeway basic segment based on interactive influence of explanatory variables
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作者 王晓飞 李新伟 +2 位作者 符锌砂 赵立萱 刘小峰 《Journal of Southeast University(English Edition)》 EI CAS 2015年第2期276-281,共6页
In order to improve the prediction precision of the safety performance function (SPF) of freeway basic segments, design and crash data of 640 segments are collected from different institutions. Three negative binomi... In order to improve the prediction precision of the safety performance function (SPF) of freeway basic segments, design and crash data of 640 segments are collected from different institutions. Three negative binomial (NB) regression models and three generalized negative binomial (GNB) regression models are built to prove that the interactive influence of explanatory variables plays an important role in fitting goodness. The effective use of the GNB model in analyzing the interactive influence of explanatory variables and predicting freeway basic segments is demonstrated. Among six models, the two models (one is the NB model and the other is the GNB model. ) which consider the interactive influence of the annual average daily traffic (AADT) and length are more reasonable for predicting results. Furthermore, a comprehensive study is carried out to prove that when considering the interactive influence, the NB and GNB models have almost the same fitting performance in estimating the crashes, among which the GNB model is slightly better for prediction performance. 展开更多
关键词 CRASH FREEWAY safety performance function( SPF interactive influence of explanatory variables generalized negative binomial (GNB)
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A Structured Mesh Euler and Interactive Boundary Layer Method for Wing/Body Configurations
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作者 李杰 周洲 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2008年第1期19-27,共9页
To compute transonic flows over a complex 3D aircraft configuration, a viscous/inviscid interaction method is developed by coupling an integral boundary-layer solver with an Eluer solver in a "semi-inverse" manner. ... To compute transonic flows over a complex 3D aircraft configuration, a viscous/inviscid interaction method is developed by coupling an integral boundary-layer solver with an Eluer solver in a "semi-inverse" manner. For the turbulent boundary-layer, an integral method using Green's lag equation is coupled with the outer inviscid flow. A blowing velocity approach is used to simulate the displacement effects of the boundary layer. To predict the aerodynamic drag, it is developed a numerical technique called far-field method that is based on the momentum theorem, in which the total drag is divided into three component drags, i.e. viscous, induced and wave-formed. Consequently, it can provide more physical insight into the drag sources than the often-used surface integral technique. The drag decomposition can be achieved with help of the second law of thermodynamics, which implies that entropy increases and total pressure decreases only across shock wave along a streamline of an inviscid non-isentropic flow. This method has been applied to the DLR-F4 wing/body configuration showing results in good agreement with the wind tunnel data. 展开更多
关键词 viscous/inviscid interaction far-field drag prediction transonic flow wing/body configuration
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Neuronal guidance signaling in neurodegenerative diseases:Key regulators that function at neuron-glia and neuroimmune interfaces
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作者 Junichi Yuasa-Kawada Mariko Kinoshita-Kawada +6 位作者 Masaki Hiramoto Satoru Yamagishi Takayasu Mishima Shin’ichiro Yasunaga Yoshio Tsuboi Nobutaka Hattori Jane Y.Wu 《Neural Regeneration Research》 2026年第2期612-635,共24页
The nervous system processes a vast amount of information,performing computations that underlie perception,cognition,and behavior.During development,neuronal guidance genes,which encode extracellular cues,their recept... The nervous system processes a vast amount of information,performing computations that underlie perception,cognition,and behavior.During development,neuronal guidance genes,which encode extracellular cues,their receptors,and downstream signal transducers,organize neural wiring to generate the complex architecture of the nervous system.It is now evident that many of these neuroguidance cues and their receptors are active during development and are also expressed in the adult nervous system.This suggests that neuronal guidance pathways are critical not only for neural wiring but also for ongoing function and maintenance of the mature nervous system.Supporting this view,these pathways continue to regulate synaptic connectivity,plasticity,and remodeling,and overall brain homeostasis throughout adulthood.Genetic and transcriptomic analyses have further revealed many neuronal guidance genes to be associated with a wide range of neurodegenerative and neuropsychiatric disorders.Although the precise mechanisms by which aberrant neuronal guidance signaling drives the pathogenesis of these diseases remain to be clarified,emerging evidence points to several common themes,including dysfunction in neurons,microglia,astrocytes,and endothelial cells,along with dysregulation of neuron-microglia-astrocyte,neuroimmune,and neurovascular interactions.In this review,we explore recent advances in understanding the molecular and cellular mechanisms by which aberrant neuronal guidance signaling contributes to disease pathogenesis through altered cell-cell interactions.For instance,recent studies have unveiled two distinct semaphorin-plexin signaling pathways that affect microglial activation and neuroinflammation.We discuss the challenges ahead,along with the therapeutic potentials of targeting neuronal guidance pathways for treating neurodegenerative diseases.Particular focus is placed on how neuronal guidance mechanisms control neuron-glia and neuroimmune interactions and modulate microglial function under physiological and pathological conditions.Specifically,we examine the crosstalk between neuronal guidance signaling and TREM2,a master regulator of microglial function,in the context of pathogenic protein aggregates.It is well-established that age is a major risk factor for neurodegeneration.Future research should address how aging and neuronal guidance signaling interact to influence an individual’s susceptibility to various late-onset neurological diseases and how the progression of these diseases could be therapeutically blocked by targeting neuronal guidance pathways. 展开更多
关键词 amyloid-β axon guidance neurodegeneration neuroimmune interactions NEUROINFLAMMATION neuron-glia interactions neurovascular interactions SEMAPHORIN synaptic remodeling tau TDP-43 TREM2 Α-SYNUCLEIN
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三段式“interactive”教学模式在“农业机械学”课程教学中的应用研究 被引量:6
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作者 罗海峰 谢方平 吴明亮 《高等农业教育》 2018年第4期68-72,共5页
农业机械学作为农业机械化及其自动化专业的专业核心课程,其教学质量的好坏直接决定专业培养质量。传统的教学方法已经不适应时代的发展和教学质量提高的需求,因此,构建三段式"interactive"教学模式,并在农业机械学课程教学... 农业机械学作为农业机械化及其自动化专业的专业核心课程,其教学质量的好坏直接决定专业培养质量。传统的教学方法已经不适应时代的发展和教学质量提高的需求,因此,构建三段式"interactive"教学模式,并在农业机械学课程教学中应用,结果表明该模式在专业课程教学方法手段的创新、学生创新能力的培养、学科的发展等方面具有积极深远的影响。 展开更多
关键词 农业机械学 课程教学 互动模式
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