The influence of Impedance Boundary Condition (IBC) on transonic compressors is investigated. A systematic input–output analytical framework is developed, which treats the nonlinearities as unknown forcing terms. The...The influence of Impedance Boundary Condition (IBC) on transonic compressors is investigated. A systematic input–output analytical framework is developed, which treats the nonlinearities as unknown forcing terms. The framework is validated through the experiments of rotating inlet distortion within a low-speed compressor. The input–output method is subsequently applied to transonic compressors, including NASA Rotor37 and Stage35, wherein impedance optimization is studied along with the exploration of its fundamental mechanisms. The IBC is employed to model the effect of Casing Treatment (CT). The optimal complex impedance values are determined through predicted results and tested across a range of circumferential modes and forcing frequencies. The IBC significantly reduces the energy and Reynolds stress gain, notably at the first-order circumferential mode and within the Rotor Rotating Frequency (RRF) range. Output modes reveal that transonic compressors with fine-tuned impedance values exhibit a more confined perturbation distribution and redistribute the perturbations compared to the uncontrolled case. Additionally, the roles of resistance and reactance are elucidated through input–output analysis, and resistance determines the energy transfer direction between flow and pressure waves and modulates the amplitude, whereas reactance modifies the phase relationships and attenuates the perturbations.展开更多
The paper assesses the economic impacts of the natural forest protection program （NFPP） on the economy of Yunnan Province, China.in terms of gross output, value added,employment, and household income. An inputoutput...The paper assesses the economic impacts of the natural forest protection program （NFPP） on the economy of Yunnan Province, China.in terms of gross output, value added,employment, and household income. An inputoutput model is developed to estimate NFPP＇s economic impacts by means of backward linkages in the forestry sector and logging and haudage sector. It is found than the NFPP has positive impacts on gross output, value added and houschold income in the initial year, but has significantly negative impacts on the regional economy in the following years as the investment decreases.展开更多
Input-output analysis is widely employed to analyze inventories of a product＇s embodied energy and environmental burdens. However, input-output analysis focuses only on the production stage and ignores other life cyc...Input-output analysis is widely employed to analyze inventories of a product＇s embodied energy and environmental burdens. However, input-output analysis focuses only on the production stage and ignores other life cycle phases. Input-output analysis is not exactly a LCA （life cycle assessment） method in the strict sense of ISO 14040 standards, which must cover all stages of a product＇s life cycle, ＂from the cradle to the grave＂, so to speak. A tiered hybrid LCA is a useful tool that covers all life cycle stages by combining a process analysis with the input-output analysis method. This study aims to extend input-output analysis to the use, disposal, and recycling stages by using matrix-based method. The new method is applied to the analysis of the embodied CO2 emissions of a refrigerator as a case study. The entire life cycle C02 emissions are estimated to be 2.9 tons, including indirect emissions, and the reduction in CO2 emissions due to recycling steel scrap is calculated as 48.5 kg. The authors conclude that the new method enables a consistent inventory analysis for all life cycle stages by combining process and input-output methods.展开更多
The aim of this paper is to analyze the Mexican energy system and its greenhouse gas (GHG) emissions for the year 2012 and to estimate a baseline scenario for 2026 using an input-output analysis. The elasticity of emi...The aim of this paper is to analyze the Mexican energy system and its greenhouse gas (GHG) emissions for the year 2012 and to estimate a baseline scenario for 2026 using an input-output analysis. The elasticity of emissions with respect to national demand is calculated in order to identify the total and distributed effects of CO2 equivalent (CO2-eq) emissions. In this framework, the analysis evaluates the effects in the economy related to changes in individual sector demands, and, vice versa, the effect on individual sectors due to global changes in national demands. Results show that passenger and freight transport, power generation, iron and steel industry, chemical industry, air transportation and agriculture concentrate the largest potential for mitigation strategies, and also have important distributive effects on the Mexican economy. Results are evaluated under the mitigation strategies of industrial sector proposed by the Fifth Assessment Report of the IPCC.展开更多
In this paper, we attempted to calculate the impact of environmental regulation on the international competitiveness of China＇s industries. Calculations are based on the input-output model that incorporates pollution...In this paper, we attempted to calculate the impact of environmental regulation on the international competitiveness of China＇s industries. Calculations are based on the input-output model that incorporates pollution control costs. We took enterprises ＇pollution control costs as the substitute variable for environmental regulation and price changes to measure the impact on international competitiveness for all sectors. Our studies reported three findings. First, price rises caused by pollution control costs were not more than 4 per cent in the manufacturing and trade sectors in 2007. Second, although the charging rate on pollutant discharge has become increasingly higher since 2003, the resultant price rise is only around O. 5 per cent across all sectors. Third, the impact brought about by increasingly stronger environmental regulation is limited and the resultant price rise does not exceed 2 per cent. Thesefindings indicate that the impact of environmental regulation on China＇s trade sectors is affordable. Therefore, it is needless to worry that environmental regulation will weaken the international competitiveness of Chinese products.展开更多
Six new lanthanide complexes:[Ln(3,4-DEOBA)3(4,4'-DM-2,2'-bipy)]2·2C_(2)H_(5)OH,[Ln=Dy(1),Eu(2),Tb(3),Sm(4),Ho(5),Gd(6);3,4-DEOBA-=3,4-diethoxybenzoate,4,4'-DM-2,2'-bipy=4,4'-dimethyl-2,2'...Six new lanthanide complexes:[Ln(3,4-DEOBA)3(4,4'-DM-2,2'-bipy)]2·2C_(2)H_(5)OH,[Ln=Dy(1),Eu(2),Tb(3),Sm(4),Ho(5),Gd(6);3,4-DEOBA-=3,4-diethoxybenzoate,4,4'-DM-2,2'-bipy=4,4'-dimethyl-2,2'-bipyridine]were successfully synthesized by the volatilization of the solution at room temperature.The crystal structures of six complexes were determined by single-crystal X-ray diffraction technology.The results showed that the complexes all have a binuclear structure,and the structures contain free ethanol molecules.Moreover,the coordination number of the central metal of each structural unit is eight.Adjacent structural units interact with each other through hydrogen bonds and further expand to form 1D chain-like and 2D planar structures.After conducting a systematic study on the luminescence properties of complexes 1-4,their emission and excitation spectra were obtained.Experimental results indicated that the fluorescence lifetimes of complexes 2 and 3 were 0.807 and 0.845 ms,respectively.The emission spectral data of complexes 1-4 were imported into the CIE chromaticity coordinate system,and their corre sponding luminescent regions cover the yellow light,red light,green light,and orange-red light bands,respectively.Within the temperature range of 299.15-1300 K,the thermal decomposition processes of the six complexes were comprehensively analyzed by using TG-DSC/FTIR/MS technology.The hypothesis of the gradual loss of ligand groups during the decomposition process was verified by detecting the escaped gas,3D infrared spectroscopy,and ion fragment information detected by mass spectrometry.The specific decomposition path is as follows:firstly,free ethanol molecules and neutral ligands are removed,and finally,acidic ligands are released;the final product is the corresponding metal oxide.CCDC:2430420,1;2430422,2;2430419,3;2430424,4;2430421,5;2430423,6.展开更多
Border-associated macrophages are located at the interface between the brain and the periphery, including the perivascular spaces, choroid plexus, and meninges. Until recently, the functions of border-associated macro...Border-associated macrophages are located at the interface between the brain and the periphery, including the perivascular spaces, choroid plexus, and meninges. Until recently, the functions of border-associated macrophages have been poorly understood and largely overlooked. However, a recent study reported that border-associated macrophages participate in stroke-induced inflammation, although many details and the underlying mechanisms remain unclear. In this study, we performed a comprehensive single-cell analysis of mouse border-associated macrophages using sequencing data obtained from the Gene Expression Omnibus(GEO) database(GSE174574 and GSE225948). Differentially expressed genes were identified, and enrichment analysis was performed to identify the transcription profile of border-associated macrophages. CellChat analysis was conducted to determine the cell communication network of border-associated macrophages. Transcription factors were predicted using the ‘pySCENIC' tool. We found that, in response to hypoxia, borderassociated macrophages underwent dynamic transcriptional changes and participated in the regulation of inflammatory-related pathways. Notably, the tumor necrosis factor pathway was activated by border-associated macrophages following ischemic stroke. The pySCENIC analysis indicated that the activity of signal transducer and activator of transcription 3(Stat3) was obviously upregulated in stroke, suggesting that Stat3 inhibition may be a promising strategy for treating border-associated macrophages-induced neuroinflammation. Finally, we constructed an animal model to investigate the effects of border-associated macrophages depletion following a stroke. Treatment with liposomes containing clodronate significantly reduced infarct volume in the animals and improved neurological scores compared with untreated animals. Taken together, our results demonstrate comprehensive changes in border-associated macrophages following a stroke, providing a theoretical basis for targeting border-associated macrophages-induced neuroinflammation in stroke treatment.展开更多
Background:Receptor-interacting protein kinases(RIPKs)regulate cell death,inflammation,and immune responses,yet their roles in cancer are not fully understood.This study investigates the expression,genomic alterations...Background:Receptor-interacting protein kinases(RIPKs)regulate cell death,inflammation,and immune responses,yet their roles in cancer are not fully understood.This study investigates the expression,genomic alterations,and functional implications of RIPK family members across various cancers.Methods:We collected multi-omics data from The Cancer Genome Atlas and other public databases,including gene expression,copy number variation(CNV),mutation,methylation,tumor mutation burden(TMB),and microsatellite instability(MSI).Differential expression and survival analyses were performed using DESeq2 and Cox proportional hazards models.CNV and mutation data were analyzed with GISTIC2 and Mutect2,and methylation data with the ChAMP package.Correlations with TMB and MSI were assessed using Pearson coefficients,and gene set enrichment analysis was conducted with the MSigDB Hallmark gene sets.Results:RIPK family members show significant differential expression in various cancers,with RIPK1 and RIPK4 frequently altered.Survival analysis reveals heterogeneous impacts on overall survival.CNV and mutation analyses identify high alteration frequencies for RIPK2 and RIPK7,affecting gene expression.RIPK1 and RIPK7 are hypermethylated in several cancers,inversely correlating with RIPK3 expression.RIPK1,RIPK2,RIPK5,RIPK6,and RIPK7 correlate positively with TMB,while RIPK3 shows negative correlations in some cancers.MSI analysis indicates associations with DNA mismatch repair.G ene set enrichment analysis highlights immune-related pathway enrichment for RIPK1,RIPK2,RIPK3,and RIPK6,and cell proliferation and DNA repair pathways for RIPK4 and RIPK5.RIPK family members showed heterogeneous alterations across cancers:for example,RIPK7 was mutated in up to~15%of u terine c orpus e ndometrial c arcinoma and l ung s quamous c ell c arcinoma cases,and RIPK1 and RIPK7 exhibited frequent promoter hypermethylation in multiple tumor types.Several genes displayed context-dependent associations with overall survival and with TMB/MSI.Conclusion:This pan-cancer analysis of the RIPK family reveals their diverse roles and potential as biomarkers and therapeutic targets.The findings emphasize the importance of RIPK genes in tumorigenesis and suggest context-dependent functions across cancer types.Further studies are needed to explore their mechanisms in cancer development and clinical applications.展开更多
The sulfation and decomposition process has proven effective in selectively extracting lithium from lepidolite.It is essential to clarify the thermochemical behavior and kinetic parameters of decomposition reactions.A...The sulfation and decomposition process has proven effective in selectively extracting lithium from lepidolite.It is essential to clarify the thermochemical behavior and kinetic parameters of decomposition reactions.Accordingly,comprehensive kinetic study by employing thermalgravimetric analysis at various heating rates was presented in this paper.Two main weight loss regions were observed during heating.The initial region corresponded to the dehydration of crystal water,whereas the subsequent region with overlapping peaks involved complex decomposition reactions.The overlapping peaks were separated into two individual reaction peaks and the activation energy of each peak was calculated using isoconversional kinetics methods.The activation energy of peak 1 exhibited a continual increase as the reaction conversion progressed,while that of peak 2 steadily decreased.The optimal kinetic models,identified as belonging to the random nucleation and subsequent growth category,provided valuable insights into the mechanism of the decomposition reactions.Furthermore,the adjustment factor was introduced to reconstruct the kinetic mechanism models,and the reconstructed models described the kinetic mechanism model more accurately for the decomposition reactions.This study enhanced the understanding of the thermochemical behavior and kinetic parameters of the lepidolite sulfation product decomposition reactions,further providing theoretical basis for promoting the selective extraction of lithium.展开更多
AIM:To present an overview of the research on global glaucoma treatment in the last decade in terms of publication year,journals,countries/regions,organizations,references,and keywords,to investigate the current resea...AIM:To present an overview of the research on global glaucoma treatment in the last decade in terms of publication year,journals,countries/regions,organizations,references,and keywords,to investigate the current research international trends and hot topics in this area.METHODS:Bibliometric analysis was conducted on 9128 articles in the Web of Science Core Collection(WoSCC;Clarivate)database.Quantitative and qualitative analysis was employed using VOSviewer(v1.6.18),Pajek(v1.0.0.0),and CiteSpace(v6.1.R2)software.RESULTS:The 9128 papers relating to glaucoma treatment were published from April 2013 to April 2023,of which 7482 articles(82%)were original research articles and 1464(18%)were review articles.The United States(2867)and Johns Hopkins University(166)were the most productive country and institution,respectively,but the University College London had the highest h-index(54).The Journal of Glaucoma was the most productive and Ophthalmology had the highest h-index compared with other journals.The Keywords of interest included treatment surgery,cyclophotocoagulation,minimally invasive glaucoma surgery(MIGS),trabeculectomy,baerveldt,epidemiology,medication adherence,nanoparticle,optical coherence tomography(OCT),gene therapy,and artificial intelligence(AI).Glaucoma surgery appeared as a current research hotspot through the analysis of keywords.CONCLUSION:This study provides insights into the research trends and potential research hotspots in the treatment of glaucoma.This will help researchers to evaluate research policies and to promote international cooperation.展开更多
This paper investigates the reliability of internal marine combustion engines using an integrated approach that combines Fault Tree Analysis(FTA)and Bayesian Networks(BN).FTA provides a structured,top-down method for ...This paper investigates the reliability of internal marine combustion engines using an integrated approach that combines Fault Tree Analysis(FTA)and Bayesian Networks(BN).FTA provides a structured,top-down method for identifying critical failure modes and their root causes,while BN introduces flexibility in probabilistic reasoning,enabling dynamic updates based on new evidence.This dual methodology overcomes the limitations of static FTA models,offering a comprehensive framework for system reliability analysis.Critical failures,including External Leakage(ELU),Failure to Start(FTS),and Overheating(OHE),were identified as key risks.By incorporating redundancy into high-risk components such as pumps and batteries,the likelihood of these failures was significantly reduced.For instance,redundant pumps reduced the probability of ELU by 31.88%,while additional batteries decreased the occurrence of FTS by 36.45%.The results underscore the practical benefits of combining FTA and BN for enhancing system reliability,particularly in maritime applications where operational safety and efficiency are critical.This research provides valuable insights for maintenance planning and highlights the importance of redundancy in critical systems,especially as the industry transitions toward more autonomous vessels.展开更多
To ensure the safe transportation of radioactive materials,numerous countries have established specific standards.For the transfer of fissile materials,it is imperative that the material within the packaging remains i...To ensure the safe transportation of radioactive materials,numerous countries have established specific standards.For the transfer of fissile materials,it is imperative that the material within the packaging remains in a subcritical state during routine,normal,and accidental transport conditions.In the event of an accident,the rods within the storage tank may become rearranged,introducing uncertainty that must be accounted for to ensure that criticality analysis results are conservative.Historically,this uncertainty was addressed overly conservatively due to limited research on non-uniform arrangement scenarios,which proved unsuitable for criticality safety analysis of spent fuel packages.This paper introduced three distinct methods to non-uniformly rearrange fuel rods—Uniform Arrangement by Blocks,Layer-by-Layer Determination,and Birdcage Deformation—and meticulously evaluates the influences of rod rearrangement on the effective multiplication factor of neutrons,k eff,utilizing the Monte Carlo method.Ultimately,this study presents a holistic method capable of encompassing the entire spectrum of potential effects stemming from the rearrangement of fuel rods during rods mispositioning accident.By augmenting the safety margin,this approach proves to be adeptly suited for the criticality safety analysis of nuclear fuel transport containers.展开更多
Industrial waste salts are commonly used to make value-added snow-melting agents to ensure traffic safety in northern China during winter and spring after snowfall.However,heavy metals in industrial waste salts may po...Industrial waste salts are commonly used to make value-added snow-melting agents to ensure traffic safety in northern China during winter and spring after snowfall.However,heavy metals in industrial waste salts may pose certain environmental risks.Snow-melting agents and snow samples were collected and analyzed from highways,arterial roads,footbridges,and other locations in Beijing after the snowstorm in December 2023.It was found that the main component of snow-melting agents was sodium chloride with high concentrations of Cu,Mn,and Zn,which are not regulated in the current policies,despite the recent promotion of environmentally friendly snow-melting agents.The Pb,Zn and Cr contents of some snow samples exceeded the limitation value of surface water quality standards,potentially affecting the soil and water environment near roadsides,although the snow-melting agents comply with relevant standards,which indicates the policy gap in the management of recycled industrial salts.We reviewed and analyzed the relevant standards for snow-melting agents and industrial waste salts proposed nationally and internationally over the past 30 years.Through comparative analysis,we proposed relevant policy recommendations to the existing quality standards of snow-melting agents and the management regulations of industrial waste salts,and the formulation of corresponding usage strategies,aimed at reducing the potential environmental release of heavy metals from the use of snow-melting agents,thereby promoting more sustainable green urban development and environmentally sound waste management.展开更多
Background:Epidemiological studies have confirmed that longer exposure to insecticides like cypermethrin(CYP)significantly increases the risk of male reproductive toxicity.Crocus sativus L.has been recognized due to i...Background:Epidemiological studies have confirmed that longer exposure to insecticides like cypermethrin(CYP)significantly increases the risk of male reproductive toxicity.Crocus sativus L.has been recognized due to its therapeutic properties,but its exact role and molecular mechanisms in treatment of reproductive dysfunction remain unclear.Methods:During this study,36 rats were randomly divided into six groups(n=6):control,CYP-induced(60 mg/kg),standard(leuprolide 3 mg/kg)and three treatment groups receiving aqueous,ethanolic,and oil extracts(50 mg/kg or 20 mL/kg)for post-toxicity induction.Results:The finding represented that exposure of CYP significantly increased oxidative stress,disrupted testicular architecture,and markedly reduced testosterone levels(P<0.05).Importantly,Crocus sativus L.treatment alleviated these changes by increasing the expression of Nrf2(nuclear factor erythroid 2-related factor 2),restoring the activity of antioxidant enzymes,and enhancing testicular histomorphology.Surprisingly,molecular docking established a high binding affinity of Crocus sativus L.phytoconstituents such as gallic acid,cinnamic acid and quercetin to the Nrf2-Keap1 complex.It is worth noting that,Crocus sativus L.exhibited a high level of protection against reproductive toxicity caused by CYP in male rats,which was mediated by the activation of Nrf2 pathway,reduction of oxidative damage,and favorable ADMET characteristics.Conclusion:Notably,this research provides a more valid,safe,and effective method of developing new drugs for reproductive disorders,however,further investigation is needed to support the research findings and implement it in clinical practice.展开更多
China is the largest CH4 emitter in the world. Given the importance of CH4 in greenhouse gas emission inventories, the characteristics ofChina＇s CH4 emissions at different scales deserve to be fully understood. Prese...China is the largest CH4 emitter in the world. Given the importance of CH4 in greenhouse gas emission inventories, the characteristics ofChina＇s CH4 emissions at different scales deserve to be fully understood. Presented in this paper is an interprovincial input output embodi- ment analysis of China＇s regional CH4 emissions in 2007, based on the most recently available multi-regional input- output table, and relevant CH4 emissions data. The results show that the eastern, central and western areas contribute to 48.2%, 28.6%, and 23.3% of the national total embodied emissions, respectively. Guangdong has the highest level of embodied CH4 emissions among all of the 30 regions. The Agriculture sector produces the most embodied CH4 emissions in final demand, followed by the Construction, Food Production and Tobacco Processing, and Other Service Activities sectors. Significant net transfers of embodied CH4 emission flows are identified from the central and western areas to the eastern area via interregional trade. Shanxi is the largest interregional exporter of embodied CH4 emissions. In contrast, Guangdong is the largest interregional importer. Energy activities, agricultural activities, and waste management comprise 65.6%, 30.7%, and 3.7% of the total embodied CH4 emissions in interregional trade, respectively. By using consumption-based accounting principles, the emis- sion magnitudes, per capita emissions, and emission intensities of most eastern regions increase remarkably, while those of some central and western regions decrease largely. To achieve regional CH4 emission mitigation, comprehensive mitigation measures should be designed under consideration of regional transfer of emission responsibility.展开更多
Using the most detailed and recent statistics available for Beijing, a local-scale embodiment analysis on water use was conducted, employing a systems input- output analysis that integrates economic systems with natur...Using the most detailed and recent statistics available for Beijing, a local-scale embodiment analysis on water use was conducted, employing a systems input- output analysis that integrates economic systems with natural resources data. Systems analysis for water research at the local scale is a crucial part of a systems oriented water accounting framework. To our knowledge, however, related works have not been thoroughly conducted. In this paper, a set of embodied water intensity inventory data is presented, which is applicable to both intermediate input and final demand. Also, detailed analyses of Beijing＇s embodied water use accounting are presented. The embodied water intensity of the. Water Production and Supply Industry Sector turns out to be the highest among the 42 sectors. For water embodied in final demand, the total amount is 3.48 km3, of which the water embodied in urban household consumption makes up nearly a half proportion. As a net virtual water importer, Beijing＇s water embodied in commodity trade totals 5.84× 10^8m3. As a result, in addition to improvements in technology and water use efficiency, adjustments in industrial structure and trade policies are algo of significant importance to water conservation efforts.展开更多
Some problems exist in the current carbon emissions benchmark setting systems. The primary con- sideration for industrial carbon emissions standards highly relate to direct carbon emissions （power-related emissions）...Some problems exist in the current carbon emissions benchmark setting systems. The primary con- sideration for industrial carbon emissions standards highly relate to direct carbon emissions （power-related emissions） and only a portion of indirect emissions are considered in the current carbon emissions accounting processes. This practice is insufficient and may cause double counting to some extent due to mixed emission sources. To better integrate and quantify direct and indirect carbon emissions, an embodied industrial carbon emissions benchmark setting method is proposed to guide the establishment of carbon emissions benchmarks based on input-output analysis. This method attempts to link direct carbon emissions with inter-industrial economic exchanges and systematically quantifies carbon emissions embodied in total product delivery chains. The purpose of this study is to design a practical new set of embodied intensity-based benchmarks for both direct and indirect carbon emissions. Beijing, at the first level of carbon emissions trading pilot schemes in China, plays a significant role in the establish- ment of these schemes and is chosen as an example in this study. The newly proposed method tends to relate emissions directly to each responsibility in a practical way through the measurement of complex production and supply chains and reduce carbon emissions from their original sources. This method is expected to be developed under uncertain internal and external contexts and is further expected to be generalized to guide the establish- ment of industrial benchmarks for carbon emissions trading schemes in China and other countries.展开更多
Based on an input-output analysis, this paper compiles inventories of fuel-related CO2 emissions of Hubei economy in the years of 2002, 2005, and 2007. Results show that calculated total direct CO2 emissions rose from...Based on an input-output analysis, this paper compiles inventories of fuel-related CO2 emissions of Hubei economy in the years of 2002, 2005, and 2007. Results show that calculated total direct CO2 emissions rose from 114,462.69 kt （2002） to 196,650.31 kt （2005）, reaching 210,419.93 kt in 2007, with an average 22.50% rate of increase. Raw coal was the dominant source of the direct emissions throughout the three years. The sector of Electric Power, Heat Production, and Supply was the main direct emissions contributor, with the largest intensities observed from 2002 （1192.97 g/CNY） to 2007 （1739.15 g/ CNY）. From the industrial perspective, the secondary industry, which is characterized as manufacture of finished products, was still the pillar of the Hubei economy during this period concerned, contributing more than 80% of the total direct emissions. As a net exporter of embodied CO2 emissions in 2002 and 2007, Hubei reported net-exported emissions of 4109.00 kt and 17,871.77 kt respectively; however, Hubei was once a net importer of CO2 emissions in 2005 （2511.93 kt）. The CO2 emissions embodied in export and fixed capital formation had the two leading fractions of emissions embodied in the final use. The corresponding countermeasures, such as promoting renew- able and clean energy and properly reducing the exports of low value added and carbon-intensive products are suggestions for reducing CO2 emissions in Hubei.展开更多
Global production networks have become the most important organizational platforms for coordinating international production activities,and their evolution patterns profoundly affect value distribution across the worl...Global production networks have become the most important organizational platforms for coordinating international production activities,and their evolution patterns profoundly affect value distribution across the world.In this study,we shall firstly carry out an in-depth quantitative research to analyze the patterns and evolution of global production networks,using a long time-sequenced multi-region input-output table and the network analysis approach.Then based on the method of value-added decomposition,we will develop an index system to measure the degree of participation of regions in global production networks.Finally,we will try to identify the factors affecting the degree of participation of countries in global production networks by constructing a regression model.The results show that from 1995 to 2015,the evolution of global production networks measured by input-output linkages experienced four stages:expansion,contraction,re-expansion,and re-contraction.In addition,the core communities of global production networks evolved from two major production communities(Europe and the Americas)to three pillars(Europe,Americas,and Asia)while more segmented communities are mainly affected by geographical proximity.The latter consists of European,North American,South American,African and Asian communities.The evolution of the global production network pattern primarily manifests as a process of cooperation strengthening or weakening among communities,based on changes in the external environment and the need for individual development strategies.Meanwhile,the United States,Germany,and the United Kingdom have consistently ranked among the top entities in global production networks,whereas China,Russia,and Southeast Asia have the fastest rises in ranking.In addition,government efficiency,resources endowment,infrastructure conditions and technology levels play important roles in the participation in global production networks.展开更多
基金co-supported by the National Natural Science Foundation of China(Nos.52325602,52306036 and 52306035)the National Science and Technology Major Project of China(No.Y2022-II-0003-0006 and Y2022-II-0002-0005)+1 种基金the project funded by China Postdoctoral Science Foundation(No.2022M720346)supported by the Key Laboratory of Pre-Research Management Centre of China(No.6142702200101).
文摘The influence of Impedance Boundary Condition (IBC) on transonic compressors is investigated. A systematic input–output analytical framework is developed, which treats the nonlinearities as unknown forcing terms. The framework is validated through the experiments of rotating inlet distortion within a low-speed compressor. The input–output method is subsequently applied to transonic compressors, including NASA Rotor37 and Stage35, wherein impedance optimization is studied along with the exploration of its fundamental mechanisms. The IBC is employed to model the effect of Casing Treatment (CT). The optimal complex impedance values are determined through predicted results and tested across a range of circumferential modes and forcing frequencies. The IBC significantly reduces the energy and Reynolds stress gain, notably at the first-order circumferential mode and within the Rotor Rotating Frequency (RRF) range. Output modes reveal that transonic compressors with fine-tuned impedance values exhibit a more confined perturbation distribution and redistribute the perturbations compared to the uncontrolled case. Additionally, the roles of resistance and reactance are elucidated through input–output analysis, and resistance determines the energy transfer direction between flow and pressure waves and modulates the amplitude, whereas reactance modifies the phase relationships and attenuates the perturbations.
文摘The paper assesses the economic impacts of the natural forest protection program （NFPP） on the economy of Yunnan Province, China.in terms of gross output, value added,employment, and household income. An inputoutput model is developed to estimate NFPP＇s economic impacts by means of backward linkages in the forestry sector and logging and haudage sector. It is found than the NFPP has positive impacts on gross output, value added and houschold income in the initial year, but has significantly negative impacts on the regional economy in the following years as the investment decreases.
文摘Input-output analysis is widely employed to analyze inventories of a product＇s embodied energy and environmental burdens. However, input-output analysis focuses only on the production stage and ignores other life cycle phases. Input-output analysis is not exactly a LCA （life cycle assessment） method in the strict sense of ISO 14040 standards, which must cover all stages of a product＇s life cycle, ＂from the cradle to the grave＂, so to speak. A tiered hybrid LCA is a useful tool that covers all life cycle stages by combining a process analysis with the input-output analysis method. This study aims to extend input-output analysis to the use, disposal, and recycling stages by using matrix-based method. The new method is applied to the analysis of the embodied CO2 emissions of a refrigerator as a case study. The entire life cycle C02 emissions are estimated to be 2.9 tons, including indirect emissions, and the reduction in CO2 emissions due to recycling steel scrap is calculated as 48.5 kg. The authors conclude that the new method enables a consistent inventory analysis for all life cycle stages by combining process and input-output methods.
文摘The aim of this paper is to analyze the Mexican energy system and its greenhouse gas (GHG) emissions for the year 2012 and to estimate a baseline scenario for 2026 using an input-output analysis. The elasticity of emissions with respect to national demand is calculated in order to identify the total and distributed effects of CO2 equivalent (CO2-eq) emissions. In this framework, the analysis evaluates the effects in the economy related to changes in individual sector demands, and, vice versa, the effect on individual sectors due to global changes in national demands. Results show that passenger and freight transport, power generation, iron and steel industry, chemical industry, air transportation and agriculture concentrate the largest potential for mitigation strategies, and also have important distributive effects on the Mexican economy. Results are evaluated under the mitigation strategies of industrial sector proposed by the Fifth Assessment Report of the IPCC.
文摘In this paper, we attempted to calculate the impact of environmental regulation on the international competitiveness of China＇s industries. Calculations are based on the input-output model that incorporates pollution control costs. We took enterprises ＇pollution control costs as the substitute variable for environmental regulation and price changes to measure the impact on international competitiveness for all sectors. Our studies reported three findings. First, price rises caused by pollution control costs were not more than 4 per cent in the manufacturing and trade sectors in 2007. Second, although the charging rate on pollutant discharge has become increasingly higher since 2003, the resultant price rise is only around O. 5 per cent across all sectors. Third, the impact brought about by increasingly stronger environmental regulation is limited and the resultant price rise does not exceed 2 per cent. Thesefindings indicate that the impact of environmental regulation on China＇s trade sectors is affordable. Therefore, it is needless to worry that environmental regulation will weaken the international competitiveness of Chinese products.
文摘Six new lanthanide complexes:[Ln(3,4-DEOBA)3(4,4'-DM-2,2'-bipy)]2·2C_(2)H_(5)OH,[Ln=Dy(1),Eu(2),Tb(3),Sm(4),Ho(5),Gd(6);3,4-DEOBA-=3,4-diethoxybenzoate,4,4'-DM-2,2'-bipy=4,4'-dimethyl-2,2'-bipyridine]were successfully synthesized by the volatilization of the solution at room temperature.The crystal structures of six complexes were determined by single-crystal X-ray diffraction technology.The results showed that the complexes all have a binuclear structure,and the structures contain free ethanol molecules.Moreover,the coordination number of the central metal of each structural unit is eight.Adjacent structural units interact with each other through hydrogen bonds and further expand to form 1D chain-like and 2D planar structures.After conducting a systematic study on the luminescence properties of complexes 1-4,their emission and excitation spectra were obtained.Experimental results indicated that the fluorescence lifetimes of complexes 2 and 3 were 0.807 and 0.845 ms,respectively.The emission spectral data of complexes 1-4 were imported into the CIE chromaticity coordinate system,and their corre sponding luminescent regions cover the yellow light,red light,green light,and orange-red light bands,respectively.Within the temperature range of 299.15-1300 K,the thermal decomposition processes of the six complexes were comprehensively analyzed by using TG-DSC/FTIR/MS technology.The hypothesis of the gradual loss of ligand groups during the decomposition process was verified by detecting the escaped gas,3D infrared spectroscopy,and ion fragment information detected by mass spectrometry.The specific decomposition path is as follows:firstly,free ethanol molecules and neutral ligands are removed,and finally,acidic ligands are released;the final product is the corresponding metal oxide.CCDC:2430420,1;2430422,2;2430419,3;2430424,4;2430421,5;2430423,6.
基金supported by Qingdao Key Medical and Health Discipline ProjectThe Intramural Research Program of the Affiliated Hospital of Qingdao University,No. 4910Qingdao West Coast New Area Science and Technology Project,No. 2020-55 (all to SW)。
文摘Border-associated macrophages are located at the interface between the brain and the periphery, including the perivascular spaces, choroid plexus, and meninges. Until recently, the functions of border-associated macrophages have been poorly understood and largely overlooked. However, a recent study reported that border-associated macrophages participate in stroke-induced inflammation, although many details and the underlying mechanisms remain unclear. In this study, we performed a comprehensive single-cell analysis of mouse border-associated macrophages using sequencing data obtained from the Gene Expression Omnibus(GEO) database(GSE174574 and GSE225948). Differentially expressed genes were identified, and enrichment analysis was performed to identify the transcription profile of border-associated macrophages. CellChat analysis was conducted to determine the cell communication network of border-associated macrophages. Transcription factors were predicted using the ‘pySCENIC' tool. We found that, in response to hypoxia, borderassociated macrophages underwent dynamic transcriptional changes and participated in the regulation of inflammatory-related pathways. Notably, the tumor necrosis factor pathway was activated by border-associated macrophages following ischemic stroke. The pySCENIC analysis indicated that the activity of signal transducer and activator of transcription 3(Stat3) was obviously upregulated in stroke, suggesting that Stat3 inhibition may be a promising strategy for treating border-associated macrophages-induced neuroinflammation. Finally, we constructed an animal model to investigate the effects of border-associated macrophages depletion following a stroke. Treatment with liposomes containing clodronate significantly reduced infarct volume in the animals and improved neurological scores compared with untreated animals. Taken together, our results demonstrate comprehensive changes in border-associated macrophages following a stroke, providing a theoretical basis for targeting border-associated macrophages-induced neuroinflammation in stroke treatment.
基金supported by grants from the Tianjin Health Technology Project(Grant no.2022QN106).
文摘Background:Receptor-interacting protein kinases(RIPKs)regulate cell death,inflammation,and immune responses,yet their roles in cancer are not fully understood.This study investigates the expression,genomic alterations,and functional implications of RIPK family members across various cancers.Methods:We collected multi-omics data from The Cancer Genome Atlas and other public databases,including gene expression,copy number variation(CNV),mutation,methylation,tumor mutation burden(TMB),and microsatellite instability(MSI).Differential expression and survival analyses were performed using DESeq2 and Cox proportional hazards models.CNV and mutation data were analyzed with GISTIC2 and Mutect2,and methylation data with the ChAMP package.Correlations with TMB and MSI were assessed using Pearson coefficients,and gene set enrichment analysis was conducted with the MSigDB Hallmark gene sets.Results:RIPK family members show significant differential expression in various cancers,with RIPK1 and RIPK4 frequently altered.Survival analysis reveals heterogeneous impacts on overall survival.CNV and mutation analyses identify high alteration frequencies for RIPK2 and RIPK7,affecting gene expression.RIPK1 and RIPK7 are hypermethylated in several cancers,inversely correlating with RIPK3 expression.RIPK1,RIPK2,RIPK5,RIPK6,and RIPK7 correlate positively with TMB,while RIPK3 shows negative correlations in some cancers.MSI analysis indicates associations with DNA mismatch repair.G ene set enrichment analysis highlights immune-related pathway enrichment for RIPK1,RIPK2,RIPK3,and RIPK6,and cell proliferation and DNA repair pathways for RIPK4 and RIPK5.RIPK family members showed heterogeneous alterations across cancers:for example,RIPK7 was mutated in up to~15%of u terine c orpus e ndometrial c arcinoma and l ung s quamous c ell c arcinoma cases,and RIPK1 and RIPK7 exhibited frequent promoter hypermethylation in multiple tumor types.Several genes displayed context-dependent associations with overall survival and with TMB/MSI.Conclusion:This pan-cancer analysis of the RIPK family reveals their diverse roles and potential as biomarkers and therapeutic targets.The findings emphasize the importance of RIPK genes in tumorigenesis and suggest context-dependent functions across cancer types.Further studies are needed to explore their mechanisms in cancer development and clinical applications.
基金financially supported by the National Natural Science Foundation of China(Nos.52034002 and U2202254)the Fundamental Research Funds for the Central Universities,China(No.FRF-TT-19-001)。
文摘The sulfation and decomposition process has proven effective in selectively extracting lithium from lepidolite.It is essential to clarify the thermochemical behavior and kinetic parameters of decomposition reactions.Accordingly,comprehensive kinetic study by employing thermalgravimetric analysis at various heating rates was presented in this paper.Two main weight loss regions were observed during heating.The initial region corresponded to the dehydration of crystal water,whereas the subsequent region with overlapping peaks involved complex decomposition reactions.The overlapping peaks were separated into two individual reaction peaks and the activation energy of each peak was calculated using isoconversional kinetics methods.The activation energy of peak 1 exhibited a continual increase as the reaction conversion progressed,while that of peak 2 steadily decreased.The optimal kinetic models,identified as belonging to the random nucleation and subsequent growth category,provided valuable insights into the mechanism of the decomposition reactions.Furthermore,the adjustment factor was introduced to reconstruct the kinetic mechanism models,and the reconstructed models described the kinetic mechanism model more accurately for the decomposition reactions.This study enhanced the understanding of the thermochemical behavior and kinetic parameters of the lepidolite sulfation product decomposition reactions,further providing theoretical basis for promoting the selective extraction of lithium.
基金Suppotred by Tianjin Key Medical Discipline Construction Project(No.TJYXZDXK-3-004A-2).
文摘AIM:To present an overview of the research on global glaucoma treatment in the last decade in terms of publication year,journals,countries/regions,organizations,references,and keywords,to investigate the current research international trends and hot topics in this area.METHODS:Bibliometric analysis was conducted on 9128 articles in the Web of Science Core Collection(WoSCC;Clarivate)database.Quantitative and qualitative analysis was employed using VOSviewer(v1.6.18),Pajek(v1.0.0.0),and CiteSpace(v6.1.R2)software.RESULTS:The 9128 papers relating to glaucoma treatment were published from April 2013 to April 2023,of which 7482 articles(82%)were original research articles and 1464(18%)were review articles.The United States(2867)and Johns Hopkins University(166)were the most productive country and institution,respectively,but the University College London had the highest h-index(54).The Journal of Glaucoma was the most productive and Ophthalmology had the highest h-index compared with other journals.The Keywords of interest included treatment surgery,cyclophotocoagulation,minimally invasive glaucoma surgery(MIGS),trabeculectomy,baerveldt,epidemiology,medication adherence,nanoparticle,optical coherence tomography(OCT),gene therapy,and artificial intelligence(AI).Glaucoma surgery appeared as a current research hotspot through the analysis of keywords.CONCLUSION:This study provides insights into the research trends and potential research hotspots in the treatment of glaucoma.This will help researchers to evaluate research policies and to promote international cooperation.
基金supported by Istanbul Technical University(Project No.45698)supported through the“Young Researchers’Career Development Project-training of doctoral students”of the Croatian Science Foundation.
文摘This paper investigates the reliability of internal marine combustion engines using an integrated approach that combines Fault Tree Analysis(FTA)and Bayesian Networks(BN).FTA provides a structured,top-down method for identifying critical failure modes and their root causes,while BN introduces flexibility in probabilistic reasoning,enabling dynamic updates based on new evidence.This dual methodology overcomes the limitations of static FTA models,offering a comprehensive framework for system reliability analysis.Critical failures,including External Leakage(ELU),Failure to Start(FTS),and Overheating(OHE),were identified as key risks.By incorporating redundancy into high-risk components such as pumps and batteries,the likelihood of these failures was significantly reduced.For instance,redundant pumps reduced the probability of ELU by 31.88%,while additional batteries decreased the occurrence of FTS by 36.45%.The results underscore the practical benefits of combining FTA and BN for enhancing system reliability,particularly in maritime applications where operational safety and efficiency are critical.This research provides valuable insights for maintenance planning and highlights the importance of redundancy in critical systems,especially as the industry transitions toward more autonomous vessels.
文摘To ensure the safe transportation of radioactive materials,numerous countries have established specific standards.For the transfer of fissile materials,it is imperative that the material within the packaging remains in a subcritical state during routine,normal,and accidental transport conditions.In the event of an accident,the rods within the storage tank may become rearranged,introducing uncertainty that must be accounted for to ensure that criticality analysis results are conservative.Historically,this uncertainty was addressed overly conservatively due to limited research on non-uniform arrangement scenarios,which proved unsuitable for criticality safety analysis of spent fuel packages.This paper introduced three distinct methods to non-uniformly rearrange fuel rods—Uniform Arrangement by Blocks,Layer-by-Layer Determination,and Birdcage Deformation—and meticulously evaluates the influences of rod rearrangement on the effective multiplication factor of neutrons,k eff,utilizing the Monte Carlo method.Ultimately,this study presents a holistic method capable of encompassing the entire spectrum of potential effects stemming from the rearrangement of fuel rods during rods mispositioning accident.By augmenting the safety margin,this approach proves to be adeptly suited for the criticality safety analysis of nuclear fuel transport containers.
基金supported by the National Natural Science Foundation of China(No.22176200)the Industrial Innovation Entrepreneurial Team Project of Ordos 2021.
文摘Industrial waste salts are commonly used to make value-added snow-melting agents to ensure traffic safety in northern China during winter and spring after snowfall.However,heavy metals in industrial waste salts may pose certain environmental risks.Snow-melting agents and snow samples were collected and analyzed from highways,arterial roads,footbridges,and other locations in Beijing after the snowstorm in December 2023.It was found that the main component of snow-melting agents was sodium chloride with high concentrations of Cu,Mn,and Zn,which are not regulated in the current policies,despite the recent promotion of environmentally friendly snow-melting agents.The Pb,Zn and Cr contents of some snow samples exceeded the limitation value of surface water quality standards,potentially affecting the soil and water environment near roadsides,although the snow-melting agents comply with relevant standards,which indicates the policy gap in the management of recycled industrial salts.We reviewed and analyzed the relevant standards for snow-melting agents and industrial waste salts proposed nationally and internationally over the past 30 years.Through comparative analysis,we proposed relevant policy recommendations to the existing quality standards of snow-melting agents and the management regulations of industrial waste salts,and the formulation of corresponding usage strategies,aimed at reducing the potential environmental release of heavy metals from the use of snow-melting agents,thereby promoting more sustainable green urban development and environmentally sound waste management.
文摘Background:Epidemiological studies have confirmed that longer exposure to insecticides like cypermethrin(CYP)significantly increases the risk of male reproductive toxicity.Crocus sativus L.has been recognized due to its therapeutic properties,but its exact role and molecular mechanisms in treatment of reproductive dysfunction remain unclear.Methods:During this study,36 rats were randomly divided into six groups(n=6):control,CYP-induced(60 mg/kg),standard(leuprolide 3 mg/kg)and three treatment groups receiving aqueous,ethanolic,and oil extracts(50 mg/kg or 20 mL/kg)for post-toxicity induction.Results:The finding represented that exposure of CYP significantly increased oxidative stress,disrupted testicular architecture,and markedly reduced testosterone levels(P<0.05).Importantly,Crocus sativus L.treatment alleviated these changes by increasing the expression of Nrf2(nuclear factor erythroid 2-related factor 2),restoring the activity of antioxidant enzymes,and enhancing testicular histomorphology.Surprisingly,molecular docking established a high binding affinity of Crocus sativus L.phytoconstituents such as gallic acid,cinnamic acid and quercetin to the Nrf2-Keap1 complex.It is worth noting that,Crocus sativus L.exhibited a high level of protection against reproductive toxicity caused by CYP in male rats,which was mediated by the activation of Nrf2 pathway,reduction of oxidative damage,and favorable ADMET characteristics.Conclusion:Notably,this research provides a more valid,safe,and effective method of developing new drugs for reproductive disorders,however,further investigation is needed to support the research findings and implement it in clinical practice.
文摘China is the largest CH4 emitter in the world. Given the importance of CH4 in greenhouse gas emission inventories, the characteristics ofChina＇s CH4 emissions at different scales deserve to be fully understood. Presented in this paper is an interprovincial input output embodi- ment analysis of China＇s regional CH4 emissions in 2007, based on the most recently available multi-regional input- output table, and relevant CH4 emissions data. The results show that the eastern, central and western areas contribute to 48.2%, 28.6%, and 23.3% of the national total embodied emissions, respectively. Guangdong has the highest level of embodied CH4 emissions among all of the 30 regions. The Agriculture sector produces the most embodied CH4 emissions in final demand, followed by the Construction, Food Production and Tobacco Processing, and Other Service Activities sectors. Significant net transfers of embodied CH4 emission flows are identified from the central and western areas to the eastern area via interregional trade. Shanxi is the largest interregional exporter of embodied CH4 emissions. In contrast, Guangdong is the largest interregional importer. Energy activities, agricultural activities, and waste management comprise 65.6%, 30.7%, and 3.7% of the total embodied CH4 emissions in interregional trade, respectively. By using consumption-based accounting principles, the emis- sion magnitudes, per capita emissions, and emission intensities of most eastern regions increase remarkably, while those of some central and western regions decrease largely. To achieve regional CH4 emission mitigation, comprehensive mitigation measures should be designed under consideration of regional transfer of emission responsibility.
文摘Using the most detailed and recent statistics available for Beijing, a local-scale embodiment analysis on water use was conducted, employing a systems input- output analysis that integrates economic systems with natural resources data. Systems analysis for water research at the local scale is a crucial part of a systems oriented water accounting framework. To our knowledge, however, related works have not been thoroughly conducted. In this paper, a set of embodied water intensity inventory data is presented, which is applicable to both intermediate input and final demand. Also, detailed analyses of Beijing＇s embodied water use accounting are presented. The embodied water intensity of the. Water Production and Supply Industry Sector turns out to be the highest among the 42 sectors. For water embodied in final demand, the total amount is 3.48 km3, of which the water embodied in urban household consumption makes up nearly a half proportion. As a net virtual water importer, Beijing＇s water embodied in commodity trade totals 5.84× 10^8m3. As a result, in addition to improvements in technology and water use efficiency, adjustments in industrial structure and trade policies are algo of significant importance to water conservation efforts.
文摘Some problems exist in the current carbon emissions benchmark setting systems. The primary con- sideration for industrial carbon emissions standards highly relate to direct carbon emissions （power-related emissions） and only a portion of indirect emissions are considered in the current carbon emissions accounting processes. This practice is insufficient and may cause double counting to some extent due to mixed emission sources. To better integrate and quantify direct and indirect carbon emissions, an embodied industrial carbon emissions benchmark setting method is proposed to guide the establishment of carbon emissions benchmarks based on input-output analysis. This method attempts to link direct carbon emissions with inter-industrial economic exchanges and systematically quantifies carbon emissions embodied in total product delivery chains. The purpose of this study is to design a practical new set of embodied intensity-based benchmarks for both direct and indirect carbon emissions. Beijing, at the first level of carbon emissions trading pilot schemes in China, plays a significant role in the establish- ment of these schemes and is chosen as an example in this study. The newly proposed method tends to relate emissions directly to each responsibility in a practical way through the measurement of complex production and supply chains and reduce carbon emissions from their original sources. This method is expected to be developed under uncertain internal and external contexts and is further expected to be generalized to guide the establish- ment of industrial benchmarks for carbon emissions trading schemes in China and other countries.
基金Acknowledgements The authors acknowledge financial support from the National Natural Science Foundation of China （Grant Nos. 51306067 and 51376076）.
文摘Based on an input-output analysis, this paper compiles inventories of fuel-related CO2 emissions of Hubei economy in the years of 2002, 2005, and 2007. Results show that calculated total direct CO2 emissions rose from 114,462.69 kt （2002） to 196,650.31 kt （2005）, reaching 210,419.93 kt in 2007, with an average 22.50% rate of increase. Raw coal was the dominant source of the direct emissions throughout the three years. The sector of Electric Power, Heat Production, and Supply was the main direct emissions contributor, with the largest intensities observed from 2002 （1192.97 g/CNY） to 2007 （1739.15 g/ CNY）. From the industrial perspective, the secondary industry, which is characterized as manufacture of finished products, was still the pillar of the Hubei economy during this period concerned, contributing more than 80% of the total direct emissions. As a net exporter of embodied CO2 emissions in 2002 and 2007, Hubei reported net-exported emissions of 4109.00 kt and 17,871.77 kt respectively; however, Hubei was once a net importer of CO2 emissions in 2005 （2511.93 kt）. The CO2 emissions embodied in export and fixed capital formation had the two leading fractions of emissions embodied in the final use. The corresponding countermeasures, such as promoting renew- able and clean energy and properly reducing the exports of low value added and carbon-intensive products are suggestions for reducing CO2 emissions in Hubei.
基金Strategic Priority Research Program of Chinese Academy of Sciences,No.XDA20080000National Natural Science Foundation of China,No.41901154。
文摘Global production networks have become the most important organizational platforms for coordinating international production activities,and their evolution patterns profoundly affect value distribution across the world.In this study,we shall firstly carry out an in-depth quantitative research to analyze the patterns and evolution of global production networks,using a long time-sequenced multi-region input-output table and the network analysis approach.Then based on the method of value-added decomposition,we will develop an index system to measure the degree of participation of regions in global production networks.Finally,we will try to identify the factors affecting the degree of participation of countries in global production networks by constructing a regression model.The results show that from 1995 to 2015,the evolution of global production networks measured by input-output linkages experienced four stages:expansion,contraction,re-expansion,and re-contraction.In addition,the core communities of global production networks evolved from two major production communities(Europe and the Americas)to three pillars(Europe,Americas,and Asia)while more segmented communities are mainly affected by geographical proximity.The latter consists of European,North American,South American,African and Asian communities.The evolution of the global production network pattern primarily manifests as a process of cooperation strengthening or weakening among communities,based on changes in the external environment and the need for individual development strategies.Meanwhile,the United States,Germany,and the United Kingdom have consistently ranked among the top entities in global production networks,whereas China,Russia,and Southeast Asia have the fastest rises in ranking.In addition,government efficiency,resources endowment,infrastructure conditions and technology levels play important roles in the participation in global production networks.
