Intraparietal Hernias are hernias occurring in the anterior abdominal wall at different anatomical planes. An interparietal hernia has a hernial sac that passes between the layers of the anterior abdominal wall. Appen...Intraparietal Hernias are hernias occurring in the anterior abdominal wall at different anatomical planes. An interparietal hernia has a hernial sac that passes between the layers of the anterior abdominal wall. Appendectomy is a very common surgical procedure, and post appendectomy incisional hernia is a very rare complication. Here we present a case of a 24-year-old male with swelling in the right hypochondrium and lumbar region with an open appendectomy scar. He was diagnosed to have an interparietal hernia in the anterior abdominal wall. After obtaining consent patient was taken up for surgery. At surgery, the patient was found to have a defect in the transverse abdominis muscle with a medial leaf far from the incision site. Open repair of the defect along with double breasting of external oblique done. Interparietal hernias are rare in post appendectomy scar and this case is of significance since it Highlights a rare interstitial type incisional hernia, as a complication of post appendectomy scar, and not many cases reports are mentioned in literature.展开更多
目的探索细胞外基质在疝组织改变或由于成纤维细胞转?缺陷导致切口疝发生过程中培养的成纤维细胞中I型胶原mRNA和III型胶原mRNA表达。方法成纤维细胞来自切口疝病人和复发性切口疝病人,对照组来自正常健康组织而没有经过手术皮肤病人和...目的探索细胞外基质在疝组织改变或由于成纤维细胞转?缺陷导致切口疝发生过程中培养的成纤维细胞中I型胶原mRNA和III型胶原mRNA表达。方法成纤维细胞来自切口疝病人和复发性切口疝病人,对照组来自正常健康组织而没有经过手术皮肤病人和虽有切口癍痕但无临床表现切口疝病人。用RT-PCR和North-ern B lotting确定I型胶原mRNA对III型胶原mRNA比率。结果RT-PCR结果表明了I型胶原mRNA在切口疝病人(0.90±0.04)和复发性切口疝病人(1.19±0.04)组中,标相应地在癍痕组织(0.54±0.02)和健康组织(0.43±0.01)。然而III型胶原mRNA在切口疝病人显著增加至4.13±0.04和复发性切口疝病人增加至6.02±0.03,而在癍痕组织2.29±0.04,在健康组织中为1.72±0.03。疝病人的成纤维细胞I型胶原mRNA对III型胶原mRNA比率显著减少(P<0.01)。结论在培养的皮肤成纤维细胞中I型胶原mRNA对III型胶原mRNA的比率减少,表明在切口疝病人存在胶原蛋白代谢紊乱。因此一个损伤的伤口愈合过程可能解释临床缝合修补疝组织不尽满意结果的原因。展开更多
文摘Intraparietal Hernias are hernias occurring in the anterior abdominal wall at different anatomical planes. An interparietal hernia has a hernial sac that passes between the layers of the anterior abdominal wall. Appendectomy is a very common surgical procedure, and post appendectomy incisional hernia is a very rare complication. Here we present a case of a 24-year-old male with swelling in the right hypochondrium and lumbar region with an open appendectomy scar. He was diagnosed to have an interparietal hernia in the anterior abdominal wall. After obtaining consent patient was taken up for surgery. At surgery, the patient was found to have a defect in the transverse abdominis muscle with a medial leaf far from the incision site. Open repair of the defect along with double breasting of external oblique done. Interparietal hernias are rare in post appendectomy scar and this case is of significance since it Highlights a rare interstitial type incisional hernia, as a complication of post appendectomy scar, and not many cases reports are mentioned in literature.
文摘目的探索细胞外基质在疝组织改变或由于成纤维细胞转?缺陷导致切口疝发生过程中培养的成纤维细胞中I型胶原mRNA和III型胶原mRNA表达。方法成纤维细胞来自切口疝病人和复发性切口疝病人,对照组来自正常健康组织而没有经过手术皮肤病人和虽有切口癍痕但无临床表现切口疝病人。用RT-PCR和North-ern B lotting确定I型胶原mRNA对III型胶原mRNA比率。结果RT-PCR结果表明了I型胶原mRNA在切口疝病人(0.90±0.04)和复发性切口疝病人(1.19±0.04)组中,标相应地在癍痕组织(0.54±0.02)和健康组织(0.43±0.01)。然而III型胶原mRNA在切口疝病人显著增加至4.13±0.04和复发性切口疝病人增加至6.02±0.03,而在癍痕组织2.29±0.04,在健康组织中为1.72±0.03。疝病人的成纤维细胞I型胶原mRNA对III型胶原mRNA比率显著减少(P<0.01)。结论在培养的皮肤成纤维细胞中I型胶原mRNA对III型胶原mRNA的比率减少,表明在切口疝病人存在胶原蛋白代谢紊乱。因此一个损伤的伤口愈合过程可能解释临床缝合修补疝组织不尽满意结果的原因。
