ILP-2(inhibitor of apoptosis protein-like protein-2)是新发现的凋亡抑制蛋白IAPs(inhibitor of apoptosis pro-teins),其过度表达会抑制Bax或Apaf-1/caspase-9途径所致的凋亡,从而使细胞增殖与凋亡失衡,进而促进癌细胞生长。本文从I...ILP-2(inhibitor of apoptosis protein-like protein-2)是新发现的凋亡抑制蛋白IAPs(inhibitor of apoptosis pro-teins),其过度表达会抑制Bax或Apaf-1/caspase-9途径所致的凋亡,从而使细胞增殖与凋亡失衡,进而促进癌细胞生长。本文从ILP-2的分子生物学特性、抗细胞凋亡作用机制及促进癌细胞生长等方面进行了综述,可为深入研究ILP-2提供参考。展开更多
针对目前时间敏感网络(Time Sensitive Network,TSN)中多采用离线调度,在处理动态需求时调度开销过大的问题,提出了一种适用于TSN的基于整数线性规划(Integer Linear Programming,ILP)的动态流量均衡调度算法.该算法以已生成的离线调度...针对目前时间敏感网络(Time Sensitive Network,TSN)中多采用离线调度,在处理动态需求时调度开销过大的问题,提出了一种适用于TSN的基于整数线性规划(Integer Linear Programming,ILP)的动态流量均衡调度算法.该算法以已生成的离线调度表为基础,通过一种增量计算方式,有效降低拓扑和业务变化带来的开销;同时,针对链路负载可能出现的极端情况,制订了流量均衡策略,避免出现延时瓶颈问题,进而提升通信实时性.实验数据表明,与传统静态调度算法相比,在处理动态流量时的运算时间减少,链路负载更加均衡.展开更多
Revealing the indica-japonica differentiation in parents of hybridization between indica and japonica rice and their derived lines can provide theoretical and practical bases for the breeding of practical inter-subspe...Revealing the indica-japonica differentiation in parents of hybridization between indica and japonica rice and their derived lines can provide theoretical and practical bases for the breeding of practical inter-subspecific hybrid rice. Using subspeciesspecific molecular markers ILP （intron length polymorphism） and Cheng＇s index, the indica-japonica differentiation was analyzed with special materials including 18 indica-japonica hybrid parents and 39 derived lines, which accumulated different wide compatibility and restoring genes by convergent cross method in 21 years spanning four breeding phases. The indica-japonica differentiation was detected on all tested loci in 57 materials. Among the 18 parental lines, 4 were japonica type, 5 japonicaclinous type, 8 indicaclinous type and one indica type. The japonica proportion indexes in indica restorer lines Minghui 63 and 9308 were 12.50 and 33.33 %, respectively, while that in japonica restorer line C418 was only 31.25%. Among the 39 derived lines from indica-japonica hybridization, one was japonica type, 11 japonicaclinous type, 20 indicaclinous type and 7 indica type. The japonica proportion index in Minghui 502 was only 10.42%. The results of indica and japonica classification by ILP molecular markers and Cheng＇s index were relatively consistent. The correlation coefficient between the japonica proportion index and morphology index was 0.794＊＊, while that between the indica proportion index and morphology index was -0.7662＊＊. ILP markers could be used to accurately detect the proportion of indica/japonica content in the genome of a rice variety. The results of indica-japonica differentiation analysis could make reasonable explanation for that the hybrids obtained from indica-japonica type restorer lines had obvious heterosis. This conclusion would provide important guidance in efficient use of beneficial genes of inter-subspecific hybrid rice.展开更多
文摘ILP-2(inhibitor of apoptosis protein-like protein-2)是新发现的凋亡抑制蛋白IAPs(inhibitor of apoptosis pro-teins),其过度表达会抑制Bax或Apaf-1/caspase-9途径所致的凋亡,从而使细胞增殖与凋亡失衡,进而促进癌细胞生长。本文从ILP-2的分子生物学特性、抗细胞凋亡作用机制及促进癌细胞生长等方面进行了综述,可为深入研究ILP-2提供参考。
文摘针对目前时间敏感网络(Time Sensitive Network,TSN)中多采用离线调度,在处理动态需求时调度开销过大的问题,提出了一种适用于TSN的基于整数线性规划(Integer Linear Programming,ILP)的动态流量均衡调度算法.该算法以已生成的离线调度表为基础,通过一种增量计算方式,有效降低拓扑和业务变化带来的开销;同时,针对链路负载可能出现的极端情况,制订了流量均衡策略,避免出现延时瓶颈问题,进而提升通信实时性.实验数据表明,与传统静态调度算法相比,在处理动态流量时的运算时间减少,链路负载更加均衡.
基金supported by the National Key Technologies R&D Program of China(2006BAD01A01-3)Important Specialized Science and Technology Item of Fujian Province,China (2004NZ01-4)Important Subject Fund of Science and Technology Department of Fujian Province,China(2007N0070)
文摘Revealing the indica-japonica differentiation in parents of hybridization between indica and japonica rice and their derived lines can provide theoretical and practical bases for the breeding of practical inter-subspecific hybrid rice. Using subspeciesspecific molecular markers ILP （intron length polymorphism） and Cheng＇s index, the indica-japonica differentiation was analyzed with special materials including 18 indica-japonica hybrid parents and 39 derived lines, which accumulated different wide compatibility and restoring genes by convergent cross method in 21 years spanning four breeding phases. The indica-japonica differentiation was detected on all tested loci in 57 materials. Among the 18 parental lines, 4 were japonica type, 5 japonicaclinous type, 8 indicaclinous type and one indica type. The japonica proportion indexes in indica restorer lines Minghui 63 and 9308 were 12.50 and 33.33 %, respectively, while that in japonica restorer line C418 was only 31.25%. Among the 39 derived lines from indica-japonica hybridization, one was japonica type, 11 japonicaclinous type, 20 indicaclinous type and 7 indica type. The japonica proportion index in Minghui 502 was only 10.42%. The results of indica and japonica classification by ILP molecular markers and Cheng＇s index were relatively consistent. The correlation coefficient between the japonica proportion index and morphology index was 0.794＊＊, while that between the indica proportion index and morphology index was -0.7662＊＊. ILP markers could be used to accurately detect the proportion of indica/japonica content in the genome of a rice variety. The results of indica-japonica differentiation analysis could make reasonable explanation for that the hybrids obtained from indica-japonica type restorer lines had obvious heterosis. This conclusion would provide important guidance in efficient use of beneficial genes of inter-subspecific hybrid rice.
