Sparse representation is a new signal analysis method which is receiving increasing attention in recent years. In this article, a novel scheme solving high range resolution profile automatic target recognition for gro...Sparse representation is a new signal analysis method which is receiving increasing attention in recent years. In this article, a novel scheme solving high range resolution profile automatic target recognition for ground moving targets is proposed. The sparse representation theory is applied to analyzing the components of high range resolution profiles and sparse coefficients are used to describe their features. Numerous experiments with the target type number ranging from 2 to 6 have been implemented. Results show that the proposed scheme not only provides higher recognition preciseness in real time, but also achieves more robust performance as the target type number increases.展开更多
For radar high resolution range profile (HRRP) recognition, three aspects are of great importance to improve the performance, i.e. discrimination for outlier, classification for inner and an accurate description for f...For radar high resolution range profile (HRRP) recognition, three aspects are of great importance to improve the performance, i.e. discrimination for outlier, classification for inner and an accurate description for feature space. To tackle these issues, a novel target recognition method is designed, denoted by the multiple support vectors (multi-SV) method. With the proposed method, a special framework is constructed by a treble correlate support vector model to segment the feature space to two regions with the distribution of density, and then the description and classification hyperplane for each region are achieved. Based on the support vector framework, this method needs less memory and computation complexity to fit practical radar HRRP recognition. Finally, the experiment based on the measured data verifies the excellent performance of this method.展开更多
Orthogonal frequency division multiplexing（OFDM） radar with multicarrier phase-coded waveforms has been recently introduced to achieve high range resolution.The conventional method for obtaining the high resolution ...Orthogonal frequency division multiplexing（OFDM） radar with multicarrier phase-coded waveforms has been recently introduced to achieve high range resolution.The conventional method for obtaining the high resolution range profile（HRRP） is based on matched filters.A method of synthesizing HRRP based on the fast Fourier transform（FFT） and decoding is proposed.The mathematical expressions of HRRP are derived by assuming an elementary scenario of point-scattering targets.Based on the characteristic of OFDM multicarrier signals,it mainly analyzes the influence on HRRP exerted by several factors,such as velocity compensation errors,the sampling frequency offset,and so on.The conclusions are significant for the design of the OFDM imaging radar.Finally,the simulation results demonstrate the validity of the conclusions.展开更多
A discrete model is set up for High Resolution Range Profile (HRRP) of an extended target and the model of echo from an extended target for a Stepped Chirp Radar (SCR) is proposed. The effect of target motion on a ran...A discrete model is set up for High Resolution Range Profile (HRRP) of an extended target and the model of echo from an extended target for a Stepped Chirp Radar (SCR) is proposed. The effect of target motion on a range profile is thoroughly analyzed, and based on which precision re- quirement is developed for motion compensation. By studying the time domain correlation and the rule based on the least burst error, a motion compensation algorithm which satisfies the project requirement is presented, and the cyber-emulation confirms the conclusion. At last the processor is designed by using DSP devices to realize motion compensation and target recognition.展开更多
This paper presents a new method of High Resolution Range (HRR) profile formation based on Linear Frequency Modulation (LFM) signal fusion of multiple radars with multiple frequency bands. The principle of the multipl...This paper presents a new method of High Resolution Range (HRR) profile formation based on Linear Frequency Modulation (LFM) signal fusion of multiple radars with multiple frequency bands. The principle of the multiple radars signal fusion improving the range resolution is analyzed. With the analysis of return signals received by two radars,it is derived that the phase difference between the echoes varies almost linearly with respect to the frequency if the distance between two radars is neg-ligible compared with the radar observation distance. To compensate the phase difference,an en-tropy-minimization principle based compensation algorithm is proposed. During the fusion process,the B-splines interpolation method is applied to resample the signals for Fourier transform imaging. The theoretical analysis and simulations results show the proposed method can effectively increase signal bandwidth and provide a high resolution range profile.展开更多
The approach to estimate the length of extended targets by using the bistatic high resolution range profile（ H RRP） is analyzed in this paper. The relationship between the bistatic H RRP and the monostatic H RRP of ...The approach to estimate the length of extended targets by using the bistatic high resolution range profile（ H RRP） is analyzed in this paper. The relationship between the bistatic H RRP and the monostatic H RRP of extended targets are investigated. It is demonstrated by simulations that the target length measured by the bistatic H RRP is more meaningful and accurate than that by the monostatic HRRP,though the monostatic H RRP has been well developed and widely used in target recognizing and classification. The estimation results of a cone shaped target are present and compared at the end of the paper. To assure the reliability of the simulation,the bistatic H RRP is obtained through the scattering field data calculated by a fullwave numerical method,FE-BI-MLFMA.展开更多
A multichannel noncoherent integration detection method based on high range resolution profile was presented in this paper. According to the property of the moment generating function, the distribution characteristics...A multichannel noncoherent integration detection method based on high range resolution profile was presented in this paper. According to the property of the moment generating function, the distribution characteristics of the noncoherent integrated signals with or without target presence were derived under the circumstance with noncorrelated Gaussian distribution noises. The loss of noncoherent integration was due to improper selection of integration range of cell numbers. A multi channel noncoherent integration detection scheme where the integration number in each channel va ries was proposed to solve this problem. The quality of this method for detection of various targets was evaluated. A comparison of fixed integration range cell number detection and multichannel inte gration detection for a high range resolution profile was presented. Simulation results indicated that the principle of the method was correct and performed well for unknown physical dimension targets. The method required little prior knowledge about target and was convenient for practical implementa tion.展开更多
Template database is the key to radar automation target recognition based on High Resolution Range Profile (HRRP). From the traditional perspective, average HRRP is a valid template for it can represent each HRRP with...Template database is the key to radar automation target recognition based on High Resolution Range Profile (HRRP). From the traditional perspective, average HRRP is a valid template for it can represent each HRRP without scatterer Moving Through Range Cell (MTRC). However, template database based on this assumption is always challenged by measured data. One reason is that speckle happens in the frame without scatterer MTRC. Speckle makes HRRP fluctuate sharply and not match well with the average HRRP. We precisely introduce the formation mechanism of speckle. Then, we make an insight into the principle of matching score. Based on the conclusion, we study the properties of matching score between speckled HRRP and the average HRRP. The theoretical analysis and Monte Carlo experimental results demonstrate that speckle makes HRRP not to match well with the average HRRP according to the energy ratio of speckled scatterers. On the assumption of ideal scattering centre model, speckled HRRP has a matching score less than 85% with the average HRRP if speckled scatterers occupy more than 50% energy of the target.展开更多
Abstract: A array of the azimuthally averaged range-profile vectors and the inter-class and intra-class divergence matrixesare constructed iwth many frames of the high resolution range profiles which result from radar...Abstract: A array of the azimuthally averaged range-profile vectors and the inter-class and intra-class divergence matrixesare constructed iwth many frames of the high resolution range profiles which result from radar echoes of airplanes. Takingthe methods of whitening transformation and SVD produces a system of subspace vectors for target recognition. Where-upon, a template library for target recognition is built by the projection of a class-mean vector made from the radar dataonto the subspace for recognition. By Euclidean distance, a comparison is made between the above projection and eachtemplate in the library, to decide which class the target belongs to. Finally, simulations with the experimental radar dataarte given to show that the proposed method is robust to variation in azimuth and immune to additive Gaussian noisewhen SNR≥5dB.展开更多
In this paper, we demonstrate the high resolution seismic reflection data for a depth range of several hundred meters across the Fenhe fault in Taiyuan city, China. In combination with the relevant borehole logs, thes...In this paper, we demonstrate the high resolution seismic reflection data for a depth range of several hundred meters across the Fenhe fault in Taiyuan city, China. In combination with the relevant borehole logs, these data provide useful constraints on the accurate position, geometry and deformation rate of the fault, as well as the kinematics of recent fault motion. The high resolution seismic reflection profiling revealed that the western branch of the Fenhe fault is a high angle, eastward dipping, oblique normal fault, and cutting up to the lower part of the Quaternary system. It was revealed that the top breaking point of this fault is at a depth of ～70m below the ground surface. A borehole log across the Fenhe fault permitted us to infer that there are two high angle, oppositely dipping, oblique normal faults. The eastem branch lies beneath the eastern embankment of the Fenhe river, dipping to the west and cutting into the Holocene late Pleistocene strata with a maximum vertical offset of ～8m. Another borehole log across the northern segment of the Fenhe fault indicates that the western branch of this fault has cut into the Holocene late Pleistocene strata with a maximum vertical offset of ～6m. The above mentioned data provide a minimum average Pleistocene Holocene vertical slip rate of 0 06～0 08mm/a and a maximum average large earthquake recurrence interval of 5 0～6 7ka for the Fenhe fault.展开更多
Block A was fully transferred in December 2011, and has experienced thermal connection, displacement and steam breakthrough. It is currently in the stage of "erosion adjustment". Affected by factors such as ...Block A was fully transferred in December 2011, and has experienced thermal connection, displacement and steam breakthrough. It is currently in the stage of "erosion adjustment". Affected by factors such as reservoir heterogeneity and long development time of steam flooding, the high permeability layer in the block has a single-layer breakthrough in the longitudinal direction and a one-way breakthrough of steam in the transverse direction, resulting in uneven reservoir utilization. In order to further expand the swept volume of steam and improve the efficiency of steam flooding, the multi-medium profile control and oil displacement technology research has been carried out, the formulation of high-temperature profile control agent and foaming agent has been optimized, and a reasonable injection method has been designed. The field implementation of 8 well groups has achieved remarkable oil increase effect, and this technology has broad application prospects.展开更多
Tumor cell-intrinsic programmed death-ligand 1(PD-L1)signals mediate tumor initiation,progression and metastasis,but their effects in ameloblastoma(AM)have not been reported.In this comprehensive study,we observed mar...Tumor cell-intrinsic programmed death-ligand 1(PD-L1)signals mediate tumor initiation,progression and metastasis,but their effects in ameloblastoma(AM)have not been reported.In this comprehensive study,we observed marked upregulation of PD-L1 in AM tissues and revealed the robust correlation between elevated PD-L1 expression and increased tumor growth and recurrence rates.Notably,we found that PD-L1 overexpression markedly increased self-renewal capacity and promoted tumorigenic processes and invasion in hTERT^(+)-AM cells,whereas genetic ablation of PD-L1 exerted opposing inhibitory effects.By performing highresolution single-cell profiling and thorough immunohistochemical analyses in AM patients,we delineated the intricate cellular landscape and elucidated the mechanisms underlying the aggressive phenotype and unfavorable prognosis of these tumors.Our findings revealed that hTERT^(+)-AM cells with upregulated PD-L1 expression exhibit increased proliferative potential and stem-like attributes and undergo partial epithelial-mesenchymal transition.This phenotypic shift is induced by the activation of the PI3KAKT-mTOR signaling axis;thus,this study revealed a crucial regulatory mechanism that fuels tumor growth and recurrence.Importantly,targeted inhibition of the PD-L1-PI3K-AKT-mTOR signaling axis significantly suppressed the growth of AM patientderived tumor organoids,highlighting the potential of PD-L1 blockade as a promising therapeutic approach for AM.展开更多
Objectives To study the difference between gene expressions of high (H0-8910PM) and low (HO-8910) metastatic human ovarian carcinoma cell lines and screen novel associated genes by cDNA microarray. Methods cDNA ret...Objectives To study the difference between gene expressions of high (H0-8910PM) and low (HO-8910) metastatic human ovarian carcinoma cell lines and screen novel associated genes by cDNA microarray. Methods cDNA retro-transcribed from equal quantities of mRNA derived from high and low metastatic tumor cells or normal ovarian tissues were labeled with Cy5 and Cy3 fluorescein as probes. The mixed probe was hybridized with two pieces of BioDoor 4096 double dot human whole gene chip and scanned with a ScanArray 3000 laser scanner. The acquired image was analyzed by ImaGene 3.0 software. Results A total of 355 genes with expression levels more than 3 times larger were found by comparing the HO-8910 cell with normal ovarian epithelial cells. A total of 323 genes with expression levels more than 3 times larger in HO-8910PM cells compared to normal ovarian epithelium cells were also detected. A total of 165 genes whose expression levels were more than two times those of HO-8910PM cells compared to their mother cell line (HO-8910) were detected. Twenty-one genes with expression levels 】3 times were found from comparison of these two tumor cell lines.Conclusions cDNA microarray techniques are effective in screening differential gene expression between two human ovarian cancer cell lines (H0-8910PM; HO-8910) and normal ovarian epithelial cells. These genes may be related to the genesis and development of ovarian carcinoma. Analysis of the human ovarian cancer gene expression profile with cDNA microarray may help in gene diagnosis, treatment and prevention.展开更多
High resolution range imaging with correlation processing suffers from high sidelobe pedestal in random frequency-hopping wideband radar. After the factors which affect the sidelobe pedestal being analyzed, a compress...High resolution range imaging with correlation processing suffers from high sidelobe pedestal in random frequency-hopping wideband radar. After the factors which affect the sidelobe pedestal being analyzed, a compressed sensing based algorithm for high resolution range imaging and a new minimized ll-norm criterion for motion compensation are proposed. The random hopping of the transmitted carrier frequency is converted to restricted isometry property of the observing matrix. Then practical problems of imaging model solution and signal parameter design are resolved. Due to the particularity of the proposed algorithm, two new indicators of range profile, i.e., average signal to sidelobe ratio and local similarity, are defined. The chamber measured data are adopted to testify the validity of the proposed algorithm, and simulations are performed to analyze the precision of velocity measurement as well as the performance of motion compensation. The simulation results show that the proposed algorithm has such advantages as high precision velocity measurement, low sidelobe and short period imaging, which ensure robust imaging for moving targets when signal-to-noise ratio is above 10 dB.展开更多
When range high-resolution radar is applied to target recognition,it is quite possible for the high-resolution range profiles(HRRPs)of group targets in a beam to overlap,which reduces the target recognition performanc...When range high-resolution radar is applied to target recognition,it is quite possible for the high-resolution range profiles(HRRPs)of group targets in a beam to overlap,which reduces the target recognition performance of the radar.In this paper,we propose a group target recognition method based on a weighted mean shift(weighted-MS)clustering method.During the training phase,subtarget features are extracted based on the template database,which is established through simulation or data acquisition,and the features are fed to the support vector machine(SVM)classifier to obtain the classifier parameters.In the test phase,the weighted-MS algorithm is exploited to extract the HRRP of each subtarget.Then,the features of the subtarget HRRP are extracted and used as input in the SVM classifier to be recognized.Compared to the traditional group target recognition method,the proposed method has the advantages of requiring only a small amount of computation,setting parameters automatically,and having no requirement for target motion.The experimental results based on the measured data show that the method proposed in this paper has better recognition performance and is more robust against noise than other recognition methods.展开更多
The principle and method of both radar target imaging and velocity measurement simultaneously based on step frequency waveforms is presented. Velocity compensation is necessary in order to obtain the good High resolut...The principle and method of both radar target imaging and velocity measurement simultaneously based on step frequency waveforms is presented. Velocity compensation is necessary in order to obtain the good High resolution range profile since this waveform is greatly sensitive to the Doppler shift. The velocity measurement performance of the four styles is analyzed with two pulse trains consisted of positive and negative step frequency waveforms. The velocity of targets can be estimated first coarsely by using the pulse trains with positive-positive step frequency combination, and then fine by positive-negative combination. Simulation results indicate that the method can accomplish the accurate estimation of the velocity with efficient computation and good anti-noise performance and obtain the good HRRP simultaneously.展开更多
A high resolution range profile(HRRP) is a summation vector of the sub-echoes of the target scattering points acquired by a wide-band radar.Generally, HRRPs obtained in a noncooperative complex electromagnetic environ...A high resolution range profile(HRRP) is a summation vector of the sub-echoes of the target scattering points acquired by a wide-band radar.Generally, HRRPs obtained in a noncooperative complex electromagnetic environment are contaminated by strong noise.Effective pre-processing of the HRRP data can greatly improve the accuracy of target recognition.In this paper, a denoising and reconstruction method for HRRP is proposed based on a Modified Sparse Auto-Encoder, which is a representative non-linear model.To better reconstruct the HRRP, a sparse constraint is added to the proposed model and the sparse coefficient is calculated based on the intrinsic dimension of HRRP.The denoising of the HRRP is performed by adding random noise to the input HRRP data during the training process and fine-tuning the weight matrix through singular-value decomposition.The results of simulations showed that the proposed method can both reconstruct the signal with fidelity and suppress noise effectively, significantly outperforming other methods, especially in low Signal-to-Noise Ratio conditions.展开更多
To relax the target aspect sensitivity and use more statistical information of the High Range Resolution Profiles (HRRPs), in this paper, the average range profile and the variance range profile are extracted together...To relax the target aspect sensitivity and use more statistical information of the High Range Resolution Profiles (HRRPs), in this paper, the average range profile and the variance range profile are extracted together as the feature vectors for both training data and test data representa-tion. And a decision rule is established for Automatic Target Recognition (ATR) based on the mini-mum Kullback-Leibler Distance (KLD) criterion. The recognition performance of the proposed method is comparable with that of Adaptive Gaussian Classifier (AGC) with multiple test HRRPs, but the proposed method is much more computational efficient. Experimental results based on the measured data show that the minimum KLD classifier is effective.展开更多
The mixture of factor analyzers （MFA） can accurately describe high resolution range profile （HRRP） statistical charac- teristics. But how to determine the proper number of the models is a problem. This paper devel...The mixture of factor analyzers （MFA） can accurately describe high resolution range profile （HRRP） statistical charac- teristics. But how to determine the proper number of the models is a problem. This paper develops a variational Bayesian mixture of factor analyzers （VBMFA） model. This procedure can obtain a lower bound on the Bayesian integral using the Jensen＇s inequality. An analytical solution of the Bayesian integral could be obtained by a hypothesis that latent variables in the model are indepen- dent. During computing the parameters of the model, birth-death moves are utilized to determine the optimal number of model au- tomatically. Experimental results for measured data show that the VBMFA method has better recognition performance than FA and MFA method.展开更多
To obtain the radar High Range Resolution (HRR) profile of the slowly moving ground target in strong clutter background, the Phase-Coded Hopped-Frequency (PCHF) waveform is proposed. By multiple-bursts coherent proces...To obtain the radar High Range Resolution (HRR) profile of the slowly moving ground target in strong clutter background, the Phase-Coded Hopped-Frequency (PCHF) waveform is proposed. By multiple-bursts coherent processing, the HRR profile synthesis, target velocity compensation and clutter compression can be accomplished simultaneously. The new waveform is shown to have good ability to suppress ground clutter and good Electronic Counter-CounterMeasures (ECCM) ability as well. The clutter compression performance of the proposed method is verified by the numerical results.展开更多
文摘Sparse representation is a new signal analysis method which is receiving increasing attention in recent years. In this article, a novel scheme solving high range resolution profile automatic target recognition for ground moving targets is proposed. The sparse representation theory is applied to analyzing the components of high range resolution profiles and sparse coefficients are used to describe their features. Numerous experiments with the target type number ranging from 2 to 6 have been implemented. Results show that the proposed scheme not only provides higher recognition preciseness in real time, but also achieves more robust performance as the target type number increases.
文摘For radar high resolution range profile (HRRP) recognition, three aspects are of great importance to improve the performance, i.e. discrimination for outlier, classification for inner and an accurate description for feature space. To tackle these issues, a novel target recognition method is designed, denoted by the multiple support vectors (multi-SV) method. With the proposed method, a special framework is constructed by a treble correlate support vector model to segment the feature space to two regions with the distribution of density, and then the description and classification hyperplane for each region are achieved. Based on the support vector framework, this method needs less memory and computation complexity to fit practical radar HRRP recognition. Finally, the experiment based on the measured data verifies the excellent performance of this method.
基金supported by the National Natural Science Foundation of China (6087213461072117)
文摘Orthogonal frequency division multiplexing（OFDM） radar with multicarrier phase-coded waveforms has been recently introduced to achieve high range resolution.The conventional method for obtaining the high resolution range profile（HRRP） is based on matched filters.A method of synthesizing HRRP based on the fast Fourier transform（FFT） and decoding is proposed.The mathematical expressions of HRRP are derived by assuming an elementary scenario of point-scattering targets.Based on the characteristic of OFDM multicarrier signals,it mainly analyzes the influence on HRRP exerted by several factors,such as velocity compensation errors,the sampling frequency offset,and so on.The conclusions are significant for the design of the OFDM imaging radar.Finally,the simulation results demonstrate the validity of the conclusions.
基金Supported by National Natural Science Foundation of China (No.60402032).
文摘A discrete model is set up for High Resolution Range Profile (HRRP) of an extended target and the model of echo from an extended target for a Stepped Chirp Radar (SCR) is proposed. The effect of target motion on a range profile is thoroughly analyzed, and based on which precision re- quirement is developed for motion compensation. By studying the time domain correlation and the rule based on the least burst error, a motion compensation algorithm which satisfies the project requirement is presented, and the cyber-emulation confirms the conclusion. At last the processor is designed by using DSP devices to realize motion compensation and target recognition.
文摘This paper presents a new method of High Resolution Range (HRR) profile formation based on Linear Frequency Modulation (LFM) signal fusion of multiple radars with multiple frequency bands. The principle of the multiple radars signal fusion improving the range resolution is analyzed. With the analysis of return signals received by two radars,it is derived that the phase difference between the echoes varies almost linearly with respect to the frequency if the distance between two radars is neg-ligible compared with the radar observation distance. To compensate the phase difference,an en-tropy-minimization principle based compensation algorithm is proposed. During the fusion process,the B-splines interpolation method is applied to resample the signals for Fourier transform imaging. The theoretical analysis and simulations results show the proposed method can effectively increase signal bandwidth and provide a high resolution range profile.
基金Supported by the National Natural Science Fundation of China(61001192)
文摘The approach to estimate the length of extended targets by using the bistatic high resolution range profile（ H RRP） is analyzed in this paper. The relationship between the bistatic H RRP and the monostatic H RRP of extended targets are investigated. It is demonstrated by simulations that the target length measured by the bistatic H RRP is more meaningful and accurate than that by the monostatic HRRP,though the monostatic H RRP has been well developed and widely used in target recognizing and classification. The estimation results of a cone shaped target are present and compared at the end of the paper. To assure the reliability of the simulation,the bistatic H RRP is obtained through the scattering field data calculated by a fullwave numerical method,FE-BI-MLFMA.
基金Supported by the Advanced Research Foundation of General Armament Department(51307020101)
文摘A multichannel noncoherent integration detection method based on high range resolution profile was presented in this paper. According to the property of the moment generating function, the distribution characteristics of the noncoherent integrated signals with or without target presence were derived under the circumstance with noncorrelated Gaussian distribution noises. The loss of noncoherent integration was due to improper selection of integration range of cell numbers. A multi channel noncoherent integration detection scheme where the integration number in each channel va ries was proposed to solve this problem. The quality of this method for detection of various targets was evaluated. A comparison of fixed integration range cell number detection and multichannel inte gration detection for a high range resolution profile was presented. Simulation results indicated that the principle of the method was correct and performed well for unknown physical dimension targets. The method required little prior knowledge about target and was convenient for practical implementa tion.
文摘Template database is the key to radar automation target recognition based on High Resolution Range Profile (HRRP). From the traditional perspective, average HRRP is a valid template for it can represent each HRRP without scatterer Moving Through Range Cell (MTRC). However, template database based on this assumption is always challenged by measured data. One reason is that speckle happens in the frame without scatterer MTRC. Speckle makes HRRP fluctuate sharply and not match well with the average HRRP. We precisely introduce the formation mechanism of speckle. Then, we make an insight into the principle of matching score. Based on the conclusion, we study the properties of matching score between speckled HRRP and the average HRRP. The theoretical analysis and Monte Carlo experimental results demonstrate that speckle makes HRRP not to match well with the average HRRP according to the energy ratio of speckled scatterers. On the assumption of ideal scattering centre model, speckled HRRP has a matching score less than 85% with the average HRRP if speckled scatterers occupy more than 50% energy of the target.
基金This project was supported by Advanced National Defence Program of China(41307050103)Advanced National Defence Found of China(00JS24.3.2DZ0117).
文摘Abstract: A array of the azimuthally averaged range-profile vectors and the inter-class and intra-class divergence matrixesare constructed iwth many frames of the high resolution range profiles which result from radar echoes of airplanes. Takingthe methods of whitening transformation and SVD produces a system of subspace vectors for target recognition. Where-upon, a template library for target recognition is built by the projection of a class-mean vector made from the radar dataonto the subspace for recognition. By Euclidean distance, a comparison is made between the above projection and eachtemplate in the library, to decide which class the target belongs to. Finally, simulations with the experimental radar dataarte given to show that the proposed method is robust to variation in azimuth and immune to additive Gaussian noisewhen SNR≥5dB.
文摘In this paper, we demonstrate the high resolution seismic reflection data for a depth range of several hundred meters across the Fenhe fault in Taiyuan city, China. In combination with the relevant borehole logs, these data provide useful constraints on the accurate position, geometry and deformation rate of the fault, as well as the kinematics of recent fault motion. The high resolution seismic reflection profiling revealed that the western branch of the Fenhe fault is a high angle, eastward dipping, oblique normal fault, and cutting up to the lower part of the Quaternary system. It was revealed that the top breaking point of this fault is at a depth of ～70m below the ground surface. A borehole log across the Fenhe fault permitted us to infer that there are two high angle, oppositely dipping, oblique normal faults. The eastem branch lies beneath the eastern embankment of the Fenhe river, dipping to the west and cutting into the Holocene late Pleistocene strata with a maximum vertical offset of ～8m. Another borehole log across the northern segment of the Fenhe fault indicates that the western branch of this fault has cut into the Holocene late Pleistocene strata with a maximum vertical offset of ～6m. The above mentioned data provide a minimum average Pleistocene Holocene vertical slip rate of 0 06～0 08mm/a and a maximum average large earthquake recurrence interval of 5 0～6 7ka for the Fenhe fault.
文摘Block A was fully transferred in December 2011, and has experienced thermal connection, displacement and steam breakthrough. It is currently in the stage of "erosion adjustment". Affected by factors such as reservoir heterogeneity and long development time of steam flooding, the high permeability layer in the block has a single-layer breakthrough in the longitudinal direction and a one-way breakthrough of steam in the transverse direction, resulting in uneven reservoir utilization. In order to further expand the swept volume of steam and improve the efficiency of steam flooding, the multi-medium profile control and oil displacement technology research has been carried out, the formulation of high-temperature profile control agent and foaming agent has been optimized, and a reasonable injection method has been designed. The field implementation of 8 well groups has achieved remarkable oil increase effect, and this technology has broad application prospects.
基金supported by the postdoctoral fellowship program of CPSF(GZC20241270)the China Postdoctoral Science Foundation(2024M762496).
文摘Tumor cell-intrinsic programmed death-ligand 1(PD-L1)signals mediate tumor initiation,progression and metastasis,but their effects in ameloblastoma(AM)have not been reported.In this comprehensive study,we observed marked upregulation of PD-L1 in AM tissues and revealed the robust correlation between elevated PD-L1 expression and increased tumor growth and recurrence rates.Notably,we found that PD-L1 overexpression markedly increased self-renewal capacity and promoted tumorigenic processes and invasion in hTERT^(+)-AM cells,whereas genetic ablation of PD-L1 exerted opposing inhibitory effects.By performing highresolution single-cell profiling and thorough immunohistochemical analyses in AM patients,we delineated the intricate cellular landscape and elucidated the mechanisms underlying the aggressive phenotype and unfavorable prognosis of these tumors.Our findings revealed that hTERT^(+)-AM cells with upregulated PD-L1 expression exhibit increased proliferative potential and stem-like attributes and undergo partial epithelial-mesenchymal transition.This phenotypic shift is induced by the activation of the PI3KAKT-mTOR signaling axis;thus,this study revealed a crucial regulatory mechanism that fuels tumor growth and recurrence.Importantly,targeted inhibition of the PD-L1-PI3K-AKT-mTOR signaling axis significantly suppressed the growth of AM patientderived tumor organoids,highlighting the potential of PD-L1 blockade as a promising therapeutic approach for AM.
文摘Objectives To study the difference between gene expressions of high (H0-8910PM) and low (HO-8910) metastatic human ovarian carcinoma cell lines and screen novel associated genes by cDNA microarray. Methods cDNA retro-transcribed from equal quantities of mRNA derived from high and low metastatic tumor cells or normal ovarian tissues were labeled with Cy5 and Cy3 fluorescein as probes. The mixed probe was hybridized with two pieces of BioDoor 4096 double dot human whole gene chip and scanned with a ScanArray 3000 laser scanner. The acquired image was analyzed by ImaGene 3.0 software. Results A total of 355 genes with expression levels more than 3 times larger were found by comparing the HO-8910 cell with normal ovarian epithelial cells. A total of 323 genes with expression levels more than 3 times larger in HO-8910PM cells compared to normal ovarian epithelium cells were also detected. A total of 165 genes whose expression levels were more than two times those of HO-8910PM cells compared to their mother cell line (HO-8910) were detected. Twenty-one genes with expression levels 】3 times were found from comparison of these two tumor cell lines.Conclusions cDNA microarray techniques are effective in screening differential gene expression between two human ovarian cancer cell lines (H0-8910PM; HO-8910) and normal ovarian epithelial cells. These genes may be related to the genesis and development of ovarian carcinoma. Analysis of the human ovarian cancer gene expression profile with cDNA microarray may help in gene diagnosis, treatment and prevention.
基金Project(61171133) supported by the National Natural Science Foundation of ChinaProject(CX2011B019) supported by Hunan Provincial Innovation Foundation for Postgraduate,ChinaProject(B110404) supported by Innovation Foundation for Outstanding Postgraduates of National University of Defense Technology,China
文摘High resolution range imaging with correlation processing suffers from high sidelobe pedestal in random frequency-hopping wideband radar. After the factors which affect the sidelobe pedestal being analyzed, a compressed sensing based algorithm for high resolution range imaging and a new minimized ll-norm criterion for motion compensation are proposed. The random hopping of the transmitted carrier frequency is converted to restricted isometry property of the observing matrix. Then practical problems of imaging model solution and signal parameter design are resolved. Due to the particularity of the proposed algorithm, two new indicators of range profile, i.e., average signal to sidelobe ratio and local similarity, are defined. The chamber measured data are adopted to testify the validity of the proposed algorithm, and simulations are performed to analyze the precision of velocity measurement as well as the performance of motion compensation. The simulation results show that the proposed algorithm has such advantages as high precision velocity measurement, low sidelobe and short period imaging, which ensure robust imaging for moving targets when signal-to-noise ratio is above 10 dB.
文摘When range high-resolution radar is applied to target recognition,it is quite possible for the high-resolution range profiles(HRRPs)of group targets in a beam to overlap,which reduces the target recognition performance of the radar.In this paper,we propose a group target recognition method based on a weighted mean shift(weighted-MS)clustering method.During the training phase,subtarget features are extracted based on the template database,which is established through simulation or data acquisition,and the features are fed to the support vector machine(SVM)classifier to obtain the classifier parameters.In the test phase,the weighted-MS algorithm is exploited to extract the HRRP of each subtarget.Then,the features of the subtarget HRRP are extracted and used as input in the SVM classifier to be recognized.Compared to the traditional group target recognition method,the proposed method has the advantages of requiring only a small amount of computation,setting parameters automatically,and having no requirement for target motion.The experimental results based on the measured data show that the method proposed in this paper has better recognition performance and is more robust against noise than other recognition methods.
文摘The principle and method of both radar target imaging and velocity measurement simultaneously based on step frequency waveforms is presented. Velocity compensation is necessary in order to obtain the good High resolution range profile since this waveform is greatly sensitive to the Doppler shift. The velocity measurement performance of the four styles is analyzed with two pulse trains consisted of positive and negative step frequency waveforms. The velocity of targets can be estimated first coarsely by using the pulse trains with positive-positive step frequency combination, and then fine by positive-negative combination. Simulation results indicate that the method can accomplish the accurate estimation of the velocity with efficient computation and good anti-noise performance and obtain the good HRRP simultaneously.
基金co-supported by the National Natural Science Foundation of China(Nos.61671463,61471379,61790551 and 61102166)。
文摘A high resolution range profile(HRRP) is a summation vector of the sub-echoes of the target scattering points acquired by a wide-band radar.Generally, HRRPs obtained in a noncooperative complex electromagnetic environment are contaminated by strong noise.Effective pre-processing of the HRRP data can greatly improve the accuracy of target recognition.In this paper, a denoising and reconstruction method for HRRP is proposed based on a Modified Sparse Auto-Encoder, which is a representative non-linear model.To better reconstruct the HRRP, a sparse constraint is added to the proposed model and the sparse coefficient is calculated based on the intrinsic dimension of HRRP.The denoising of the HRRP is performed by adding random noise to the input HRRP data during the training process and fine-tuning the weight matrix through singular-value decomposition.The results of simulations showed that the proposed method can both reconstruct the signal with fidelity and suppress noise effectively, significantly outperforming other methods, especially in low Signal-to-Noise Ratio conditions.
基金Partially supported by the National Natural Science Foundation of China (No.60302009).
文摘To relax the target aspect sensitivity and use more statistical information of the High Range Resolution Profiles (HRRPs), in this paper, the average range profile and the variance range profile are extracted together as the feature vectors for both training data and test data representa-tion. And a decision rule is established for Automatic Target Recognition (ATR) based on the mini-mum Kullback-Leibler Distance (KLD) criterion. The recognition performance of the proposed method is comparable with that of Adaptive Gaussian Classifier (AGC) with multiple test HRRPs, but the proposed method is much more computational efficient. Experimental results based on the measured data show that the minimum KLD classifier is effective.
基金supported in part by the National Natural Science Foundation of China(60772140)the Program for Cheung Kong Scholarsand Innovative Research Team in University(IRT0645)
文摘The mixture of factor analyzers （MFA） can accurately describe high resolution range profile （HRRP） statistical charac- teristics. But how to determine the proper number of the models is a problem. This paper develops a variational Bayesian mixture of factor analyzers （VBMFA） model. This procedure can obtain a lower bound on the Bayesian integral using the Jensen＇s inequality. An analytical solution of the Bayesian integral could be obtained by a hypothesis that latent variables in the model are indepen- dent. During computing the parameters of the model, birth-death moves are utilized to determine the optimal number of model au- tomatically. Experimental results for measured data show that the VBMFA method has better recognition performance than FA and MFA method.
基金Supported by the National Natural Science Foundation of China (No.60302009).
文摘To obtain the radar High Range Resolution (HRR) profile of the slowly moving ground target in strong clutter background, the Phase-Coded Hopped-Frequency (PCHF) waveform is proposed. By multiple-bursts coherent processing, the HRR profile synthesis, target velocity compensation and clutter compression can be accomplished simultaneously. The new waveform is shown to have good ability to suppress ground clutter and good Electronic Counter-CounterMeasures (ECCM) ability as well. The clutter compression performance of the proposed method is verified by the numerical results.
