When a population structure is modelled as a square lattice,the cooperation may be improved for an evolutionary prisoner dilemma game or be inhibited for an evolutionary snowdrift game.In this work,we investigate coop...When a population structure is modelled as a square lattice,the cooperation may be improved for an evolutionary prisoner dilemma game or be inhibited for an evolutionary snowdrift game.In this work,we investigate cooperation in a population on a square lattice where the interaction among players contains both prisoner dilemma game and snowdrift game.The heterogeneity in interaction is introduced to the population in two different ways:the heterogenous character of interaction assigned to every player(HCP) or the heterogenous character of interaction assigned to every link between any two players(HCL).The resonant enhancement of cooperation in the case of HCP is observed while the resonant inhibition of cooperation in the case of HCL is prominent.The explanations on the enhancement or inhibition of cooperation are presented for these two cases.展开更多
Atmosphere–land interactions simulated by an LES model are evaluated from the perspective of heterogeneity propagation by comparison with airborne measurements. It is found that the footprints of surface heterogeneit...Atmosphere–land interactions simulated by an LES model are evaluated from the perspective of heterogeneity propagation by comparison with airborne measurements. It is found that the footprints of surface heterogeneity, though as 2D patterns can be dissipated quickly due to turbulent mixing, as 1D projections can persist and propagate to the top of the atmospheric boundary layer. Direct comparison and length scale analysis show that the simulated heterogeneity patterns are comparable to the observation. The results highlight the model＇s capability in simulating the complex effects of surface heterogeneity on atmosphere–land interactions.展开更多
Alternative splicing(AS)regulates biological processes governing phenotypes and diseases.Differential AS(DAS)gene test methods have been developed to investigate important exonic expression from high-throughput datase...Alternative splicing(AS)regulates biological processes governing phenotypes and diseases.Differential AS(DAS)gene test methods have been developed to investigate important exonic expression from high-throughput datasets.However,the DAS events extracted using statistical tests are insufficient to delineate relevant biological processes.In this study,we developed a novel application,Alternative Splicing Encyclopedia:Functional Interaction(ASpediaFI),to systemically identify DAS events and co-regulated genes and pathways.ASpediaFI establishes a heterogeneous interaction network of genes and their feature nodes(i.e.,AS events and pathways)connected by coexpression or pathway gene set knowledge.Next,ASpediaFI explores the interaction network using the random walk with restart algorithm and interrogates the proximity from a query gene set.Finally,ASpediaFI extracts significant AS events,genes,and pathways.To evaluate the performance of our method,we simulated RNA sequencing(RNA-seq)datasets to consider various conditions of sequencing depth and sample size.The performance was compared with that of other methods.Additionally,we analyzed three public datasets of cancer patients or cell lines to evaluate how well ASpediaFI detects biologically relevant candidates.ASpediaFI exhibits strong performance in both simulated and public datasets.Our integrative approach reveals that DAS events that recognize a global co-expression network and relevant pathways determine the functional importance of spliced genes in the subnetwork.ASpediaFI is publicly available at https://bioconductor.org/packages/ASpediaFI.展开更多
Multi-robot mission planning is composed of assignment allocation and mobile-robot route planning in this paper.Multi-robot exploration missions adopts fuzzy c-mean(FCM)algorithm to allocate,and then,heterogeneous int...Multi-robot mission planning is composed of assignment allocation and mobile-robot route planning in this paper.Multi-robot exploration missions adopts fuzzy c-mean(FCM)algorithm to allocate,and then,heterogeneous interactive cultural hybrid algorithm(HICHA)is devised for route planning in order to optimize mobilerobot execution path.Meanwhile,we design multi-robot mission replanning mechanism based on the rules system of greedy algorithm for dynamic stochastic increment missions.Finally,extensive simulation experiments were shown that FCM for assignment allocation and HICHA for route planning were efficacious for mobile-robot exploration mission planning.Furthermore,the improved greedy algorithm based on experience rules met dynamic stochastic increment missions replanning requirement for load balance.展开更多
基金Supported by Natural Science Foundation of China under Grant No. 11147112
文摘When a population structure is modelled as a square lattice,the cooperation may be improved for an evolutionary prisoner dilemma game or be inhibited for an evolutionary snowdrift game.In this work,we investigate cooperation in a population on a square lattice where the interaction among players contains both prisoner dilemma game and snowdrift game.The heterogeneity in interaction is introduced to the population in two different ways:the heterogenous character of interaction assigned to every player(HCP) or the heterogenous character of interaction assigned to every link between any two players(HCL).The resonant enhancement of cooperation in the case of HCP is observed while the resonant inhibition of cooperation in the case of HCL is prominent.The explanations on the enhancement or inhibition of cooperation are presented for these two cases.
基金supported by the DFG Transregional Cooperative Research Centre 32 "Patterns in Soil-Vegetation-Atmosphere-Systems: Monitoring, Modelling and Data Assimilation"
文摘Atmosphere–land interactions simulated by an LES model are evaluated from the perspective of heterogeneity propagation by comparison with airborne measurements. It is found that the footprints of surface heterogeneity, though as 2D patterns can be dissipated quickly due to turbulent mixing, as 1D projections can persist and propagate to the top of the atmospheric boundary layer. Direct comparison and length scale analysis show that the simulated heterogeneity patterns are comparable to the observation. The results highlight the model＇s capability in simulating the complex effects of surface heterogeneity on atmosphere–land interactions.
基金supported by the Korea Research Environment Open Network (KREONET)the National Research Foundation of Korea Grant funded by the Korean government (Grant No. NRF-2019R1A2C1003401)+1 种基金the National Cancer Center Grant (Grant No. NCC-1910040)supported by Korea Research Environment Open Network(KREONE)
文摘Alternative splicing(AS)regulates biological processes governing phenotypes and diseases.Differential AS(DAS)gene test methods have been developed to investigate important exonic expression from high-throughput datasets.However,the DAS events extracted using statistical tests are insufficient to delineate relevant biological processes.In this study,we developed a novel application,Alternative Splicing Encyclopedia:Functional Interaction(ASpediaFI),to systemically identify DAS events and co-regulated genes and pathways.ASpediaFI establishes a heterogeneous interaction network of genes and their feature nodes(i.e.,AS events and pathways)connected by coexpression or pathway gene set knowledge.Next,ASpediaFI explores the interaction network using the random walk with restart algorithm and interrogates the proximity from a query gene set.Finally,ASpediaFI extracts significant AS events,genes,and pathways.To evaluate the performance of our method,we simulated RNA sequencing(RNA-seq)datasets to consider various conditions of sequencing depth and sample size.The performance was compared with that of other methods.Additionally,we analyzed three public datasets of cancer patients or cell lines to evaluate how well ASpediaFI detects biologically relevant candidates.ASpediaFI exhibits strong performance in both simulated and public datasets.Our integrative approach reveals that DAS events that recognize a global co-expression network and relevant pathways determine the functional importance of spliced genes in the subnetwork.ASpediaFI is publicly available at https://bioconductor.org/packages/ASpediaFI.
基金This work was supported in part by the National Natural Science Foundation of China(Grant No.90820302)the Research Fund for the Doctoral Program of Higher Education(No.200805330005)Hunan S&T Funds(No.06IJY3035).
文摘Multi-robot mission planning is composed of assignment allocation and mobile-robot route planning in this paper.Multi-robot exploration missions adopts fuzzy c-mean(FCM)algorithm to allocate,and then,heterogeneous interactive cultural hybrid algorithm(HICHA)is devised for route planning in order to optimize mobilerobot execution path.Meanwhile,we design multi-robot mission replanning mechanism based on the rules system of greedy algorithm for dynamic stochastic increment missions.Finally,extensive simulation experiments were shown that FCM for assignment allocation and HICHA for route planning were efficacious for mobile-robot exploration mission planning.Furthermore,the improved greedy algorithm based on experience rules met dynamic stochastic increment missions replanning requirement for load balance.
