In cosmetic surgery, golden threads have been used in thread lift procedures, wherein golden threads are placed under the skin of the neck and chin. These are mainly applied in the maxillofacial region adjacent to the...In cosmetic surgery, golden threads have been used in thread lift procedures, wherein golden threads are placed under the skin of the neck and chin. These are mainly applied in the maxillofacial region adjacent to the sites of dental treatment to achieve cosmetic benefits. However, as dentists typically lack sufficient knowledge about the golden thread lift procedure, it may present a challenge to dental examinations and treatments. It is therefore crucial for dentists to have a comprehensive understanding of the procedure. This case report covers our experience with the dental examination of a patient with golden threads. We emphasize the dental complications and precautions that should be taken for such cases. These golden threads are made of pure gold, nonabsorbable, and can be broken. These can obstruct dental examination, as well as cause metal allergies and foreign body granulomas. Additionally, it is difficult to completely remove these threads when they break apart. In the future, since more patients are expected to undergo this procedure, it is possible to encounter these golden threads as artifacts on imaging. Therefore, it is important to educate dentists about the golden thread lift procedure and its dental implications. It is also imperative to determine whether the patient has undergone the golden thread lift procedure in the medical questionnaire prior to the magnetic resonance imaging examination. Thus, dentists should be able to conduct a detailed interview with the patient, determine the feasibility of examination or treatment, and communicate this assessment to the patient.展开更多
Background:The ingestion of golden thread contaminated with heavy metals through the food chain leads to detrimental effects to human health.During digestion,not all of the heavy metals could be released to the gastro...Background:The ingestion of golden thread contaminated with heavy metals through the food chain leads to detrimental effects to human health.During digestion,not all of the heavy metals could be released to the gastrointestinal tract and readily to be absorbed by human body.Thus,bioaccessibility is an important issue in health risk assessments.Aims and Objectives:The aims and objectives of this study were to investigate the bioaccessibility of Cd in golden thread and assess the associated health risks based on the exposure to bioaccessible Cd.Materials and Methods:Inductively coupled plasma mass spectrometry(ICP-MS)has been applied to determine the Cd content in golden thread.Physiologically based extraction test(PBET)digestion was performed in the in vitro/Caco2 cell model to investigate the bioaccessibility of Cd in golden thread.Furthermore,the target hazard quotient(THQ)was used to assess the risks of the total and the bioaccessible content of Cd in golden thread.Results:The results revealed that the total Cd content in six batches of golden thread ranged from 3.203 to 5.723 mg/kg.After uptake by Caco2 cells,the bioaccessibility of Cd ranged from 42.36%to 59.73%.The results of the risk assessment indicated that prior to uptake by Caco2 cells,the THQ values of Cd for all batches of golden thread were greater than 1.However,after uptake by Caco2 cells,the THQ values of Cd in all samples were less than 1,thus suggesting that the risks were at a safe level.Conclusion:This study was the first to perform health risk assessment with bioaccessible heavy metals present in traditional Chinese medicine by PBET digestion using an in vitro/Caco2 cell model,thus enabling us to obtain more accurate and objective results while allowing us to avoid unnecessary government intervention and to establish more reasonable limit standards for heavy metals.展开更多
文摘In cosmetic surgery, golden threads have been used in thread lift procedures, wherein golden threads are placed under the skin of the neck and chin. These are mainly applied in the maxillofacial region adjacent to the sites of dental treatment to achieve cosmetic benefits. However, as dentists typically lack sufficient knowledge about the golden thread lift procedure, it may present a challenge to dental examinations and treatments. It is therefore crucial for dentists to have a comprehensive understanding of the procedure. This case report covers our experience with the dental examination of a patient with golden threads. We emphasize the dental complications and precautions that should be taken for such cases. These golden threads are made of pure gold, nonabsorbable, and can be broken. These can obstruct dental examination, as well as cause metal allergies and foreign body granulomas. Additionally, it is difficult to completely remove these threads when they break apart. In the future, since more patients are expected to undergo this procedure, it is possible to encounter these golden threads as artifacts on imaging. Therefore, it is important to educate dentists about the golden thread lift procedure and its dental implications. It is also imperative to determine whether the patient has undergone the golden thread lift procedure in the medical questionnaire prior to the magnetic resonance imaging examination. Thus, dentists should be able to conduct a detailed interview with the patient, determine the feasibility of examination or treatment, and communicate this assessment to the patient.
基金financially supported by the 13th Five-Year National Significant New Drugs Creation Feature Subjects grant(2018ZX09735006)by the Project for Medicine and Medical Instruments Review and Approval System Reform grant(ZG2016-1)
文摘Background:The ingestion of golden thread contaminated with heavy metals through the food chain leads to detrimental effects to human health.During digestion,not all of the heavy metals could be released to the gastrointestinal tract and readily to be absorbed by human body.Thus,bioaccessibility is an important issue in health risk assessments.Aims and Objectives:The aims and objectives of this study were to investigate the bioaccessibility of Cd in golden thread and assess the associated health risks based on the exposure to bioaccessible Cd.Materials and Methods:Inductively coupled plasma mass spectrometry(ICP-MS)has been applied to determine the Cd content in golden thread.Physiologically based extraction test(PBET)digestion was performed in the in vitro/Caco2 cell model to investigate the bioaccessibility of Cd in golden thread.Furthermore,the target hazard quotient(THQ)was used to assess the risks of the total and the bioaccessible content of Cd in golden thread.Results:The results revealed that the total Cd content in six batches of golden thread ranged from 3.203 to 5.723 mg/kg.After uptake by Caco2 cells,the bioaccessibility of Cd ranged from 42.36%to 59.73%.The results of the risk assessment indicated that prior to uptake by Caco2 cells,the THQ values of Cd for all batches of golden thread were greater than 1.However,after uptake by Caco2 cells,the THQ values of Cd in all samples were less than 1,thus suggesting that the risks were at a safe level.Conclusion:This study was the first to perform health risk assessment with bioaccessible heavy metals present in traditional Chinese medicine by PBET digestion using an in vitro/Caco2 cell model,thus enabling us to obtain more accurate and objective results while allowing us to avoid unnecessary government intervention and to establish more reasonable limit standards for heavy metals.
