We propose a new approach to the investigation of deterministic self-similar networks by using contractive iterated multifunction systems (briefly IMSs). Our paper focuses on the generalized version of two graph model...We propose a new approach to the investigation of deterministic self-similar networks by using contractive iterated multifunction systems (briefly IMSs). Our paper focuses on the generalized version of two graph models introduced by Barabási, Ravasz and Vicsek ([1] [2]). We generalize the graph models using stars and cliques: both algorithm construct graph sequences such that the next iteration is always based on n replicas of the current iteration, where n is the size of the initial graph structure, being a star or a clique. We analyze these self-similar graph sequences using IMSs in function of the size of the initial star and clique, respectively. Our research uses the Cantor set for the description of the fixed set of these IMSs, which we interpret as the limit object of the analyzed self-similar networks.展开更多
In this paper, a robust digital watermarking method against shearing based on Haar orthogonal function system was introduced. The proposed method adopted the complete generalized orthogonal properties of Haar ortbogon...In this paper, a robust digital watermarking method against shearing based on Haar orthogonal function system was introduced. The proposed method adopted the complete generalized orthogonal properties of Haar ortbogonal function system to achieve the piece-based orthogonal transform on the image. The significant middle frequency coefficients in the transformation matrix are picked up, based on characteristics of the image visual system and the Haar orthogonal transform. The watermark is adoptively weighed to the middle frequency matrix. The method improves the validity of watermarking and shows excellent advantage against shearing attack. Experimental results show that the Haar orthogonal function system based watermark approach can provide an excellent protection under geometric attacks.展开更多
A set of contraction maps of a metric space is called an iterated function systems. Iterated function systems with condensation, can be considered infinite iterated function systems. Infinite iterated function systems...A set of contraction maps of a metric space is called an iterated function systems. Iterated function systems with condensation, can be considered infinite iterated function systems. Infinite iterated function systems on compact metric spaces were studied. Using the properties of Banach limit and uniform contractiveness, it was proved that the random iterating algorithms for infinite iterated function systems on compact metric spaces-satisfy ergodicity. So the random iterating algorithms for iterated function systems with condensation satisfy ergodicity, too.展开更多
Random iterated function systems (IFSs) is discussed, which is one of the methods for fractal drawing. A certain figure can be reconstructed by a random IFS. One approach is presented to determine a new random IFS, th...Random iterated function systems (IFSs) is discussed, which is one of the methods for fractal drawing. A certain figure can be reconstructed by a random IFS. One approach is presented to determine a new random IFS, that the figure reconstructed by the new random IFS is the image of the origin figure reconstructed by old IFS under a given affine transformation. Two particular examples are used to show this approach.展开更多
Iterated function systems （IFS） were introduced by Hutchinson in 1981 as a natural generalization of the well-known Banach contraction principle. In 2010, D. R. Sahu and A. Chakraborty introduced K-Iterated Function...Iterated function systems （IFS） were introduced by Hutchinson in 1981 as a natural generalization of the well-known Banach contraction principle. In 2010, D. R. Sahu and A. Chakraborty introduced K-Iterated Function System using Kannan mapping which would cover a larger range of mappings. In this paper, following Hutchinson, D. R. Sahu and A. Chakraborty, we present some new iterated function systems by using the so-called generalized contractive mappings, which will also cover a large range of mappings. Our purpose is to prove the existence and uniqueness of attractors for such class of iterated function systems by virtue of a Banach-like fixed point theorem concerning generalized contractive mappings.展开更多
In this paper, we present some fixed point theorems of iterated function systems consisting of α-ψ-contractive type mappings in Fractal space constituted by the compact subset of metric space and iterated function s...In this paper, we present some fixed point theorems of iterated function systems consisting of α-ψ-contractive type mappings in Fractal space constituted by the compact subset of metric space and iterated function systems consisting of Banach contractive mappings in Fractal space constituted by the compact subset of generalized metric space, which is Mso extensively applied in topological dynamic system.展开更多
In this paper we introduce the notions of mean dimension and metric mean dimension for non-autonomous iterated function systems(NAIFSs for short)on countably infinite alphabets which can be regarded as generalizations...In this paper we introduce the notions of mean dimension and metric mean dimension for non-autonomous iterated function systems(NAIFSs for short)on countably infinite alphabets which can be regarded as generalizations of the mean dimension and the Lindenstrauss metric mean dimension for non-autonomous iterated function systems.We also show the relationship between the mean topological dimension and the metric mean dimension.展开更多
The definition of generalized product of fractal is first put forward for the research on the relations between original fractal and its product of fractal when the transformations of iteration function system （IFS）...The definition of generalized product of fractal is first put forward for the research on the relations between original fractal and its product of fractal when the transformations of iteration function system （IFS） are incomplete. Then the representations of generalized product of IFS are discussed based on the theory of the product of fractal. Furthermore, the dimensional relations between the product of fractal and its semi-product are obtained. The dimensional relations of self-similar set are discussed. Finally, the examples for rendering fractal graphs are given. These results posses potentials in image compression and pattern recognition.展开更多
Chaos game representation (CGR) of DNA sequences and linked protein sequences from genomes was proposed by Jeffrey (1990) and Yu et al. (2004), respectively. In this paper, we consider the CGR of three kinds of sequen...Chaos game representation (CGR) of DNA sequences and linked protein sequences from genomes was proposed by Jeffrey (1990) and Yu et al. (2004), respectively. In this paper, we consider the CGR of three kinds of sequences from complete genomes: whole genome DNA sequences, linked coding DNA sequences and linked protein sequences. Some fractal patterns are found in these CGRs. A recurrent iterated function systems (RIFS) model is proposed to simulate the CGRs of these sequences from genomes and their induced measures. Numerical results on 50 genomes show that the RIFS model can simulate very well the CGRs and their induced measures. The parameters estimated in the RIFS model reflect information on species classification.展开更多
Given a system {S1,…, SN} of N contractive similarities satisfying some strong separation condition, it has an invariant Set K for the system. In this article, the authors construct some random measure μω supported...Given a system {S1,…, SN} of N contractive similarities satisfying some strong separation condition, it has an invariant Set K for the system. In this article, the authors construct some random measure μω supported on random subset Kω of K, μω having some ＂non-standard＂ multifractal structure, which contrasts the well-knoWn multifractal formalism for the invariant measure of system {S1,.., SN} may possess. The main tool is the multifractal structures of a Galton-Watson tree, which are obtained by Liu [9], Shieh-Taylor [14], and MSrters-Shieh [12].展开更多
An iterated function system crossover (IFSX) operation for real-coded genetic algorithms (RCGAs) is presented in this paper. Iterated?function system (IFS) is one type of fractals that maintains a similarity character...An iterated function system crossover (IFSX) operation for real-coded genetic algorithms (RCGAs) is presented in this paper. Iterated?function system (IFS) is one type of fractals that maintains a similarity characteristic. By introducing the IFS into the crossover operation, the RCGA performs better searching solution with a faster convergence in a set of benchmark test functions.展开更多
The mature central nervous system(CNS,composed of the brain,spinal cord,olfactory and optic nerves)is unable to regenerate spontaneously after an insult,both in the cases of neurodegenerative diseases(for example Alzh...The mature central nervous system(CNS,composed of the brain,spinal cord,olfactory and optic nerves)is unable to regenerate spontaneously after an insult,both in the cases of neurodegenerative diseases(for example Alzheimer's or Parkinson's disease)or traumatic injuries(such as spinal cord lesions).In the last 20 years,the field has made significant progress in unlocking axon regrowth.展开更多
Mutations in the protocadherin-19(PCDH19)gene(Xq22.1)cause the X-linked syndrome known as developmental and epileptic encephalopathy 9(DEE9,OMIM#300088)(Dibbens et al.,2008).DEE9 is characterized by early-onset cluste...Mutations in the protocadherin-19(PCDH19)gene(Xq22.1)cause the X-linked syndrome known as developmental and epileptic encephalopathy 9(DEE9,OMIM#300088)(Dibbens et al.,2008).DEE9 is characterized by early-onset clustering epilepsy associated with intellectual disability ranging from mild to profound,autism spectrum disorder,and other neuropsychiatric features including schizophrenia,anxiety,attentiondeficit/hyperactivity,and obsessive or aggressive behaviors.While seizures may become less frequent in adolescence,psychiatric comorbidities persist and often worsen with age(Dibbens et al.,2008;Kolc et al.,2020).展开更多
This paper is concerned with event-triggered control of discrete-time systems with or without input saturation.First,an accumulative-error-based event-triggered scheme is devised for control updates.When the accumulat...This paper is concerned with event-triggered control of discrete-time systems with or without input saturation.First,an accumulative-error-based event-triggered scheme is devised for control updates.When the accumulated error between the current state and the latest control update exceeds a certain threshold,an event is triggered.Such a scheme can ensure the event-generator works at a relatively low rate rather than falls into hibernation especially after the system steps into its steady state.Second,the looped functional method for continuous-time systems is extended to discrete-time systems.By introducing an innovative looped functional that links the event-triggered scheme,some sufficient conditions for the co-design of control gain and event-triggered parameters are obtained in terms of linear matrix inequalities with a couple of tuning parameters.Then,the proposed method is applied to discrete-time systems with input saturation.As a result,both suitable control gains and event-triggered parameters are also co-designed to ensure the system trajectories converge to the region of attraction.Finally,an unstable reactor system and an inverted pendulum system are given to show the effectiveness of the proposed method.展开更多
Spinal cord injury represents a severe form of central nervous system trauma for which effective treatments remain limited.Microglia is the resident immune cells of the central nervous system,play a critical role in s...Spinal cord injury represents a severe form of central nervous system trauma for which effective treatments remain limited.Microglia is the resident immune cells of the central nervous system,play a critical role in spinal cord injury.Previous studies have shown that microglia can promote neuronal survival by phagocytosing dead cells and debris and by releasing neuroprotective and anti-inflammatory factors.However,excessive activation of microglia can lead to persistent inflammation and contribute to the formation of glial scars,which hinder axonal regeneration.Despite this,the precise role and mechanisms of microglia during the acute phase of spinal cord injury remain controversial and poorly understood.To elucidate the role of microglia in spinal cord injury,we employed the colony-stimulating factor 1 receptor inhibitor PLX5622 to deplete microglia.We observed that sustained depletion of microglia resulted in an expansion of the lesion area,downregulation of brain-derived neurotrophic factor,and impaired functional recovery after spinal cord injury.Next,we generated a transgenic mouse line with conditional overexpression of brain-derived neurotrophic factor specifically in microglia.We found that brain-derived neurotrophic factor overexpression in microglia increased angiogenesis and blood flow following spinal cord injury and facilitated the recovery of hindlimb motor function.Additionally,brain-derived neurotrophic factor overexpression in microglia reduced inflammation and neuronal apoptosis during the acute phase of spinal cord injury.Furthermore,through using specific transgenic mouse lines,TMEM119,and the colony-stimulating factor 1 receptor inhibitor PLX73086,we demonstrated that the neuroprotective effects were predominantly due to brain-derived neurotrophic factor overexpression in microglia rather than macrophages.In conclusion,our findings suggest the critical role of microglia in the formation of protective glial scars.Depleting microglia is detrimental to recovery of spinal cord injury,whereas targeting brain-derived neurotrophic factor overexpression in microglia represents a promising and novel therapeutic strategy to enhance motor function recovery in patients with spinal cord injury.展开更多
This study investigates the properties of high-purity starches extracted from Polygonum multiflorum(PMS)and Smilax glabra(SGS).The starches were characterized by scanning electron microscopy,Fouriertransform infrared ...This study investigates the properties of high-purity starches extracted from Polygonum multiflorum(PMS)and Smilax glabra(SGS).The starches were characterized by scanning electron microscopy,Fouriertransform infrared spectroscopy,X-ray diffraction,high-performance anion-exchange chromatography,and differential scanning calorimetry.Significant differences were observed in their morphological,physicochemical,and functional properties.PMS had a smaller particle size(13.68 μm),irregular polygonal shape,A-type,lower water absorption(62.67 %),and higher oil absorption(51.17 %).In contrast,SGS exhibited larger particles(31.75 μm),a nearly spherical shape,B-type,higher crystallinity(50.66 %),and greater amylose content(21.54 %),with superior thermal stability,shear resistance,and gelatinization enthalpy.SGS also contained higher resistant starch(83.28 %) and longer average chain length(20.58 %),but showed lower solubility,swelling power,light transmittance,and freeze-thaw stability.The physicochemical properties differences in crystal pattern and particle morphology between PMS and SGS lead to distinct behaviors during in vitro digestion and fermentation.These findings highlight the potential of medicinal plant starches in functional ingredients and industrial processes.展开更多
A novel parameter identification method for magnetic levitation bearing rotor systems is proposed,based on the modulation function method.The fundamental principle of the modulation function method for parameter ident...A novel parameter identification method for magnetic levitation bearing rotor systems is proposed,based on the modulation function method.The fundamental principle of the modulation function method for parameter identification is derived on the basis of the characteristics of the modulation function.The transformation of the differential equation model of a continuous system into a general algebraic equation model is effectively achieved,thereby avoiding the influence of errors introduced by the initial value and differential derivation of the system.Modulation function method parameter identification models have been established for single-degree-of-freedom and multi-degree-of-freedom magnetic levitation bearing rotor systems.The influence of different parameters of Hartley modulation function on the accuracy of system parameter identification has been investigated,thus providing a basis for the design of Hartley modulation function parameters.Simulation and experimental results demonstrate that the modulation function method can effectively identify system parameters despite the presence of system noise.展开更多
This paper presents a predefined-time controller for Multiple Space transportation Robots System (MSRS), which can be applied in on-orbit assembly tasks to transport modules to pre-assembly configuration quickly. Firs...This paper presents a predefined-time controller for Multiple Space transportation Robots System (MSRS), which can be applied in on-orbit assembly tasks to transport modules to pre-assembly configuration quickly. Firstly, to simplify the analysis and design of predefined-time controller, a Predefined-time Stability Criterion is proposed in the form of Composite Lyapunov Function (CLF-PSC). Besides simplicity, the CLF-PSC also has the advantage of less conservativeness due to utilization of initial state information. Secondly, a concept of Lp-Norm-Normalized Sign Function (LPNNSF) is proposed based on the CLF-PSC. Different from traditional norm-normalized sign function, the Lp-norm of LPNNSF can be selected arbitrarily according to practical control task requirements, which means that the proposed LPNNSF is more generalized and more convenient for calculation. Thirdly, a predefined-time disturbance observer and predefined-time controller are designed based on the LPNNSF. The observer has the property of predefined-time convergence to achieve quicker and more accurate estimation of the lumped disturbance. The controller has less control input and chattering phenomenon than traditional predefined-time controller. In addition, by introducing the observer into the controller, the closed-loop system enjoys high precision and strong robustness. Finally, the effectiveness of the proposed controller is verified by numerical simulations. By employing the controller, the MSRS can carry assembly modules to the desired pre-assembly configuration accurately within predefined time.展开更多
Dear Editor,This letter deals with the controller synthesis problem of networked Takagi-Sugeno(T-S)fuzzy systems.Due to the introduction of network communications,the same premise is no longer shared by fuzzy plants a...Dear Editor,This letter deals with the controller synthesis problem of networked Takagi-Sugeno(T-S)fuzzy systems.Due to the introduction of network communications,the same premise is no longer shared by fuzzy plants and fuzzy controllers.This makes the classic parallel distribution compensation(PDC)control infeasible.To overcome this situation,a novel method for reconstructing the membership functions'grades is proposed,which synchronizes the time scales.Then,the membership function dependent method is adopted to introduce asynchronous errors and detailed membership function information.For the event-triggered control strategy,a series of robust H∞stable conditions in LMI form are derived.Finally,a simulation of a practical system is used to demonstrate the method proposed in this letter can reduce conservatism.展开更多
Objective:To systematically evaluate the impact of phase I cardiac rehabilitation exercise prescriptions on cardiac function levels in patients after coronary intervention.Methods:Seven Chinese and English databases,i...Objective:To systematically evaluate the impact of phase I cardiac rehabilitation exercise prescriptions on cardiac function levels in patients after coronary intervention.Methods:Seven Chinese and English databases,including Cochrane Library,PubMed,Web of Science,ESC(European Society of Cardiology),and CNKI,as well as professional association websites,were searched using computers,with manual searching as a complement.Relevant literature published from the establishment of the database to February 2025 was retrieved.Two researchers independently screened the literature,extracted data,and evaluated the quality of the literature.Meta-analysis was performed using RevMan 5.3 software.Results:A total of 8 articles were included,involving 843 patients.Meta-analysis results showed that compared with routine nursing,phase I cardiac rehabilitation exercise prescriptions helped increase the 6-minute walking distance in patients after coronary intervention[MD=0.84,95%CI(0.57,1.10),P<0.001],increase the level of left ventricular ejection fraction in patients after coronary intervention[MD=0.67,95%CI(0.33,1.00),P<0.001],and cardiac rehabilitation combined with respiratory rehabilitation exercise could improve the level of left ventricular ejection fraction in patients after coronary intervention[MD=0.58,95%CI(0.40,0.76),P<0.001].Conclusion:The implementation of phase I cardiac rehabilitation exercise prescriptions can help improve cardiac function levels in patients after coronary intervention.However,the standardization of outcome evaluation indicators needs to be improved,and the long-term effects of rehabilitation still require verification through a large number of high-quality studies.展开更多
文摘We propose a new approach to the investigation of deterministic self-similar networks by using contractive iterated multifunction systems (briefly IMSs). Our paper focuses on the generalized version of two graph models introduced by Barabási, Ravasz and Vicsek ([1] [2]). We generalize the graph models using stars and cliques: both algorithm construct graph sequences such that the next iteration is always based on n replicas of the current iteration, where n is the size of the initial graph structure, being a star or a clique. We analyze these self-similar graph sequences using IMSs in function of the size of the initial star and clique, respectively. Our research uses the Cantor set for the description of the fixed set of these IMSs, which we interpret as the limit object of the analyzed self-similar networks.
文摘In this paper, a robust digital watermarking method against shearing based on Haar orthogonal function system was introduced. The proposed method adopted the complete generalized orthogonal properties of Haar ortbogonal function system to achieve the piece-based orthogonal transform on the image. The significant middle frequency coefficients in the transformation matrix are picked up, based on characteristics of the image visual system and the Haar orthogonal transform. The watermark is adoptively weighed to the middle frequency matrix. The method improves the validity of watermarking and shows excellent advantage against shearing attack. Experimental results show that the Haar orthogonal function system based watermark approach can provide an excellent protection under geometric attacks.
文摘A set of contraction maps of a metric space is called an iterated function systems. Iterated function systems with condensation, can be considered infinite iterated function systems. Infinite iterated function systems on compact metric spaces were studied. Using the properties of Banach limit and uniform contractiveness, it was proved that the random iterating algorithms for infinite iterated function systems on compact metric spaces-satisfy ergodicity. So the random iterating algorithms for iterated function systems with condensation satisfy ergodicity, too.
文摘Random iterated function systems (IFSs) is discussed, which is one of the methods for fractal drawing. A certain figure can be reconstructed by a random IFS. One approach is presented to determine a new random IFS, that the figure reconstructed by the new random IFS is the image of the origin figure reconstructed by old IFS under a given affine transformation. Two particular examples are used to show this approach.
基金Partially supported by National Natural Science Foundation of China (No. 10961003)
文摘Iterated function systems （IFS） were introduced by Hutchinson in 1981 as a natural generalization of the well-known Banach contraction principle. In 2010, D. R. Sahu and A. Chakraborty introduced K-Iterated Function System using Kannan mapping which would cover a larger range of mappings. In this paper, following Hutchinson, D. R. Sahu and A. Chakraborty, we present some new iterated function systems by using the so-called generalized contractive mappings, which will also cover a large range of mappings. Our purpose is to prove the existence and uniqueness of attractors for such class of iterated function systems by virtue of a Banach-like fixed point theorem concerning generalized contractive mappings.
基金The NSF(11271150)of ChinaChina Government Scholarship
文摘In this paper, we present some fixed point theorems of iterated function systems consisting of α-ψ-contractive type mappings in Fractal space constituted by the compact subset of metric space and iterated function systems consisting of Banach contractive mappings in Fractal space constituted by the compact subset of generalized metric space, which is Mso extensively applied in topological dynamic system.
文摘In this paper we introduce the notions of mean dimension and metric mean dimension for non-autonomous iterated function systems(NAIFSs for short)on countably infinite alphabets which can be regarded as generalizations of the mean dimension and the Lindenstrauss metric mean dimension for non-autonomous iterated function systems.We also show the relationship between the mean topological dimension and the metric mean dimension.
基金supported by National Natural Science Foundation of China (50575026, 50275013), National High-Tech. R&D Program for CIMS (2001AA412011).
文摘The definition of generalized product of fractal is first put forward for the research on the relations between original fractal and its product of fractal when the transformations of iteration function system （IFS） are incomplete. Then the representations of generalized product of IFS are discussed based on the theory of the product of fractal. Furthermore, the dimensional relations between the product of fractal and its semi-product are obtained. The dimensional relations of self-similar set are discussed. Finally, the examples for rendering fractal graphs are given. These results posses potentials in image compression and pattern recognition.
文摘Chaos game representation (CGR) of DNA sequences and linked protein sequences from genomes was proposed by Jeffrey (1990) and Yu et al. (2004), respectively. In this paper, we consider the CGR of three kinds of sequences from complete genomes: whole genome DNA sequences, linked coding DNA sequences and linked protein sequences. Some fractal patterns are found in these CGRs. A recurrent iterated function systems (RIFS) model is proposed to simulate the CGRs of these sequences from genomes and their induced measures. Numerical results on 50 genomes show that the RIFS model can simulate very well the CGRs and their induced measures. The parameters estimated in the RIFS model reflect information on species classification.
基金Both authors are supported by a grant NSC 2002/3-2115-M-002-017.
文摘Given a system {S1,…, SN} of N contractive similarities satisfying some strong separation condition, it has an invariant Set K for the system. In this article, the authors construct some random measure μω supported on random subset Kω of K, μω having some ＂non-standard＂ multifractal structure, which contrasts the well-knoWn multifractal formalism for the invariant measure of system {S1,.., SN} may possess. The main tool is the multifractal structures of a Galton-Watson tree, which are obtained by Liu [9], Shieh-Taylor [14], and MSrters-Shieh [12].
文摘An iterated function system crossover (IFSX) operation for real-coded genetic algorithms (RCGAs) is presented in this paper. Iterated?function system (IFS) is one type of fractals that maintains a similarity characteristic. By introducing the IFS into the crossover operation, the RCGA performs better searching solution with a faster convergence in a set of benchmark test functions.
基金supported by ANR(ANR-21CE16-0008-01)ANR(ANR-21-CE16-0008-02 and ANR-23CE52-0007)+1 种基金UNADEV(A22018CS)(to HN)UNADEV(A22020CS)(to SB)。
文摘The mature central nervous system(CNS,composed of the brain,spinal cord,olfactory and optic nerves)is unable to regenerate spontaneously after an insult,both in the cases of neurodegenerative diseases(for example Alzheimer's or Parkinson's disease)or traumatic injuries(such as spinal cord lesions).In the last 20 years,the field has made significant progress in unlocking axon regrowth.
基金supported by a grant from Telethon Foundation(grant No.GGP20056 to SB)The generation of Pcdh19 floxed mouse model was funded by Cariplo Foundation(grant No.2014-0972 to SB)。
文摘Mutations in the protocadherin-19(PCDH19)gene(Xq22.1)cause the X-linked syndrome known as developmental and epileptic encephalopathy 9(DEE9,OMIM#300088)(Dibbens et al.,2008).DEE9 is characterized by early-onset clustering epilepsy associated with intellectual disability ranging from mild to profound,autism spectrum disorder,and other neuropsychiatric features including schizophrenia,anxiety,attentiondeficit/hyperactivity,and obsessive or aggressive behaviors.While seizures may become less frequent in adolescence,psychiatric comorbidities persist and often worsen with age(Dibbens et al.,2008;Kolc et al.,2020).
基金supported in part by the National Natural Science Foundation of China(62473221)the Natural Science Foundation of Shandong Province,China(ZR2024MF006)Qingdao Natural Science Foundation(24-4-4-zrjj-165-jch)。
文摘This paper is concerned with event-triggered control of discrete-time systems with or without input saturation.First,an accumulative-error-based event-triggered scheme is devised for control updates.When the accumulated error between the current state and the latest control update exceeds a certain threshold,an event is triggered.Such a scheme can ensure the event-generator works at a relatively low rate rather than falls into hibernation especially after the system steps into its steady state.Second,the looped functional method for continuous-time systems is extended to discrete-time systems.By introducing an innovative looped functional that links the event-triggered scheme,some sufficient conditions for the co-design of control gain and event-triggered parameters are obtained in terms of linear matrix inequalities with a couple of tuning parameters.Then,the proposed method is applied to discrete-time systems with input saturation.As a result,both suitable control gains and event-triggered parameters are also co-designed to ensure the system trajectories converge to the region of attraction.Finally,an unstable reactor system and an inverted pendulum system are given to show the effectiveness of the proposed method.
基金supported by the National Natural Science Foundation of China,Nos.82072165 and 82272256(both to XM)the Key Project of Xiangyang Central Hospital,No.2023YZ03(to RM)。
文摘Spinal cord injury represents a severe form of central nervous system trauma for which effective treatments remain limited.Microglia is the resident immune cells of the central nervous system,play a critical role in spinal cord injury.Previous studies have shown that microglia can promote neuronal survival by phagocytosing dead cells and debris and by releasing neuroprotective and anti-inflammatory factors.However,excessive activation of microglia can lead to persistent inflammation and contribute to the formation of glial scars,which hinder axonal regeneration.Despite this,the precise role and mechanisms of microglia during the acute phase of spinal cord injury remain controversial and poorly understood.To elucidate the role of microglia in spinal cord injury,we employed the colony-stimulating factor 1 receptor inhibitor PLX5622 to deplete microglia.We observed that sustained depletion of microglia resulted in an expansion of the lesion area,downregulation of brain-derived neurotrophic factor,and impaired functional recovery after spinal cord injury.Next,we generated a transgenic mouse line with conditional overexpression of brain-derived neurotrophic factor specifically in microglia.We found that brain-derived neurotrophic factor overexpression in microglia increased angiogenesis and blood flow following spinal cord injury and facilitated the recovery of hindlimb motor function.Additionally,brain-derived neurotrophic factor overexpression in microglia reduced inflammation and neuronal apoptosis during the acute phase of spinal cord injury.Furthermore,through using specific transgenic mouse lines,TMEM119,and the colony-stimulating factor 1 receptor inhibitor PLX73086,we demonstrated that the neuroprotective effects were predominantly due to brain-derived neurotrophic factor overexpression in microglia rather than macrophages.In conclusion,our findings suggest the critical role of microglia in the formation of protective glial scars.Depleting microglia is detrimental to recovery of spinal cord injury,whereas targeting brain-derived neurotrophic factor overexpression in microglia represents a promising and novel therapeutic strategy to enhance motor function recovery in patients with spinal cord injury.
基金supported by the National Natural Science Foundation of China (No.82174074)。
文摘This study investigates the properties of high-purity starches extracted from Polygonum multiflorum(PMS)and Smilax glabra(SGS).The starches were characterized by scanning electron microscopy,Fouriertransform infrared spectroscopy,X-ray diffraction,high-performance anion-exchange chromatography,and differential scanning calorimetry.Significant differences were observed in their morphological,physicochemical,and functional properties.PMS had a smaller particle size(13.68 μm),irregular polygonal shape,A-type,lower water absorption(62.67 %),and higher oil absorption(51.17 %).In contrast,SGS exhibited larger particles(31.75 μm),a nearly spherical shape,B-type,higher crystallinity(50.66 %),and greater amylose content(21.54 %),with superior thermal stability,shear resistance,and gelatinization enthalpy.SGS also contained higher resistant starch(83.28 %) and longer average chain length(20.58 %),but showed lower solubility,swelling power,light transmittance,and freeze-thaw stability.The physicochemical properties differences in crystal pattern and particle morphology between PMS and SGS lead to distinct behaviors during in vitro digestion and fermentation.These findings highlight the potential of medicinal plant starches in functional ingredients and industrial processes.
基金supported by the National Science and Technology Major Project(Grant No.J2019-Ⅳ-0003-0070).
文摘A novel parameter identification method for magnetic levitation bearing rotor systems is proposed,based on the modulation function method.The fundamental principle of the modulation function method for parameter identification is derived on the basis of the characteristics of the modulation function.The transformation of the differential equation model of a continuous system into a general algebraic equation model is effectively achieved,thereby avoiding the influence of errors introduced by the initial value and differential derivation of the system.Modulation function method parameter identification models have been established for single-degree-of-freedom and multi-degree-of-freedom magnetic levitation bearing rotor systems.The influence of different parameters of Hartley modulation function on the accuracy of system parameter identification has been investigated,thus providing a basis for the design of Hartley modulation function parameters.Simulation and experimental results demonstrate that the modulation function method can effectively identify system parameters despite the presence of system noise.
基金co-supported by the National Natural Science Foundation of China(Nos.12372048,12102343)the Key Program of the National Natural Science Foundation of China(No.U2013206)+1 种基金the China Postdoctoral Science Foundation(No.2023M742835)the Guangdong Basic and Applied Basic Research Foundation,China(No.2023A1515011421).
文摘This paper presents a predefined-time controller for Multiple Space transportation Robots System (MSRS), which can be applied in on-orbit assembly tasks to transport modules to pre-assembly configuration quickly. Firstly, to simplify the analysis and design of predefined-time controller, a Predefined-time Stability Criterion is proposed in the form of Composite Lyapunov Function (CLF-PSC). Besides simplicity, the CLF-PSC also has the advantage of less conservativeness due to utilization of initial state information. Secondly, a concept of Lp-Norm-Normalized Sign Function (LPNNSF) is proposed based on the CLF-PSC. Different from traditional norm-normalized sign function, the Lp-norm of LPNNSF can be selected arbitrarily according to practical control task requirements, which means that the proposed LPNNSF is more generalized and more convenient for calculation. Thirdly, a predefined-time disturbance observer and predefined-time controller are designed based on the LPNNSF. The observer has the property of predefined-time convergence to achieve quicker and more accurate estimation of the lumped disturbance. The controller has less control input and chattering phenomenon than traditional predefined-time controller. In addition, by introducing the observer into the controller, the closed-loop system enjoys high precision and strong robustness. Finally, the effectiveness of the proposed controller is verified by numerical simulations. By employing the controller, the MSRS can carry assembly modules to the desired pre-assembly configuration accurately within predefined time.
基金supported by the National Natural Science Foundation of China(62173218,61833011)International International Cooperation Project of Shanghai Science and Technology Commission(21190780300).
文摘Dear Editor,This letter deals with the controller synthesis problem of networked Takagi-Sugeno(T-S)fuzzy systems.Due to the introduction of network communications,the same premise is no longer shared by fuzzy plants and fuzzy controllers.This makes the classic parallel distribution compensation(PDC)control infeasible.To overcome this situation,a novel method for reconstructing the membership functions'grades is proposed,which synchronizes the time scales.Then,the membership function dependent method is adopted to introduce asynchronous errors and detailed membership function information.For the event-triggered control strategy,a series of robust H∞stable conditions in LMI form are derived.Finally,a simulation of a practical system is used to demonstrate the method proposed in this letter can reduce conservatism.
基金Science Research Fund Project of Yunnan Provincial Department of Education(Project No.:2024J0832)Science Research Fund Project of Yunnan Provincial Department of Education(Project No.:2025Y1186)。
文摘Objective:To systematically evaluate the impact of phase I cardiac rehabilitation exercise prescriptions on cardiac function levels in patients after coronary intervention.Methods:Seven Chinese and English databases,including Cochrane Library,PubMed,Web of Science,ESC(European Society of Cardiology),and CNKI,as well as professional association websites,were searched using computers,with manual searching as a complement.Relevant literature published from the establishment of the database to February 2025 was retrieved.Two researchers independently screened the literature,extracted data,and evaluated the quality of the literature.Meta-analysis was performed using RevMan 5.3 software.Results:A total of 8 articles were included,involving 843 patients.Meta-analysis results showed that compared with routine nursing,phase I cardiac rehabilitation exercise prescriptions helped increase the 6-minute walking distance in patients after coronary intervention[MD=0.84,95%CI(0.57,1.10),P<0.001],increase the level of left ventricular ejection fraction in patients after coronary intervention[MD=0.67,95%CI(0.33,1.00),P<0.001],and cardiac rehabilitation combined with respiratory rehabilitation exercise could improve the level of left ventricular ejection fraction in patients after coronary intervention[MD=0.58,95%CI(0.40,0.76),P<0.001].Conclusion:The implementation of phase I cardiac rehabilitation exercise prescriptions can help improve cardiac function levels in patients after coronary intervention.However,the standardization of outcome evaluation indicators needs to be improved,and the long-term effects of rehabilitation still require verification through a large number of high-quality studies.
