The bolted flange structure finds significant applications in fields such as aerospace,shipbuilding,and pipeline transportation.The investigation of its dynamic characteristics has consistently been a focal point for ...The bolted flange structure finds significant applications in fields such as aerospace,shipbuilding,and pipeline transportation.The investigation of its dynamic characteristics has consistently been a focal point for researchers;however,there remains a deficiency in the development of robust analytical models.This paper introduces a novel analytical model based on the finite element methods and the Timoshenko beam theory to accurately simulate the bolted flange structure.The stiffness,mass,damping,and inertia matrices of the rotor system are individually derived,and the dynamic equation is subsequently formulated.The model’s validity and accuracy are validated through both the experimental testing and the finite element analysis.This study aims to elucidate the relationship between the external loads and the influence of the geometric configuration on the stiffness and contact behavior of the bolted flange structure,thereby enabling a thorough and precise prediction of the static and dynamic load transfer pathways,as well as the distribution of vibrational energy within the structure,while also facilitating the incorporation of friction and slip effects.Simultaneously,this work provides a foundational framework for the optimization design of bolted flange structures,addressing the factors such as the number,size,and geometric distribution of bolts.展开更多
To ensure the operational safety of railways in the landslide-prone areas of mountainous regions,a large-scale model test and numerical simulation were conducted to study the bending moment distribution,internal force...To ensure the operational safety of railways in the landslide-prone areas of mountainous regions,a large-scale model test and numerical simulation were conducted to study the bending moment distribution,internal force distribution,deformation development,and crack propagation characteristics of a framed anti-sliding structure(FAS)under landslide thrust up to the point of failure.Results show that the maximum bending moment and its increase rate in the fore pile are greater than those in the rear pile,with the maximum bending moment of the fore pile approximately 1.1 times that of the rear pile.When the FAS fails,the displacement at the top of the fore pile is significantly greater,about 1.27 times that of the rear pile in the experiment.Major cracks develop at locations corresponding to the peak bending moments.Small transverse cracks initially appear on the upper surface at the intersection between the primary beam and rear pile and then spread to the side of the structure.At the failure stage,major cracks are observed at the pil-beam intersections and near the anchor points.Strengthening flexural stiffness at intersections where major cracks occur can improve the overall thrust-deformation coordination of the FAS,thereby maximizing its performance.展开更多
The acetylpolyamine oxidase(APAO),spermine oxidase(SMO),and spermidine/spermine N1-acetyltransferase(SSAT)are pivotal enzymes in polyamine metabolism,exerting direct influence on polyamine homeostasis regulation.Dysfu...The acetylpolyamine oxidase(APAO),spermine oxidase(SMO),and spermidine/spermine N1-acetyltransferase(SSAT)are pivotal enzymes in polyamine metabolism,exerting direct influence on polyamine homeostasis regulation.Dysfunctions in these enzymes are intricately linked to inflammatory diseases and cancers.Establishing their three-dimensional structures is essential for exploring enzymatic catalytic mechanisms and designing inhibitors at the atomic level.This article primarily assesses the precision of AlphaFold2 and molecular dynamics simulations in determining the three-dimensional structures of these enzymes,utilizing protein conformation rationality assessment,residue correlation matrix,and other techniques.This provides robust models for subsequent polyamine catabolic metabolism calculations and offers valuable insights for modeling proteins that have yet to acquire crystal structures.展开更多
Beach groynes are structures for erosion protection along sandy coasts near inlets and can reduce the coastal erosion substantially,but open groynes cannot stop erosion completely because sand can be removed from the ...Beach groynes are structures for erosion protection along sandy coasts near inlets and can reduce the coastal erosion substantially,but open groynes cannot stop erosion completely because sand can be removed from the groyne compartments by cross-shore processes.Beach groynes should be designed with sufficient bypassing of sand to minimise erosion.Regular beach maintenance is required to keep a sufficient beach width for recreational purposes.The effectiveness of groyne compartments can be significantly improved by using T-head groynes or by using a submerged sill or breakwater in between the groynes.An economic evaluation shows that the beach maintenance costs over 50 years may be substantially higher than the construction costs of a submerged breakwater.An important parameter to be studied is the longshore transport,which requires detailed information of the wave climate,preferably based on measured data(offshore buoys)in combination with deep water wave modelling.Various models have been used to determine the net longshore sand transport and coastline changes.The design of groynes to reduce coastal erosion is illustrated by three field cases(Atlantic coast near Soulac,France;Lagos coast,Nigeria and Black Sea coast,Romania).These example cases show that beach groynes are effective structures,but sufficient bypassing of longshore sand transport is essential to minimise erosion.Regular beach fills in the groyne compartments may be required at high-energy(exposed)coasts.A submerged or emerged breakwater can be built between the groynes to protect the beach in the groyne compartments against erosion by cross-shore processes.展开更多
Accurate prediction of coal reservoir permeability is crucial for engineering applications,including coal mining,coalbed methane(CBM)extraction,and carbon storage in deep unmineable coal seams.Owing to the inherent he...Accurate prediction of coal reservoir permeability is crucial for engineering applications,including coal mining,coalbed methane(CBM)extraction,and carbon storage in deep unmineable coal seams.Owing to the inherent heterogeneity and complex internal structure of coal,a well-established method for predicting permeability based on microscopic fracture structures remains elusive.This paper presents a novel integrated approach that leverages the intrinsic relationship between microscopic fracture structure and permeability to construct a predictive model for coal permeability.The proposed framework encompasses data generation through the integration of three-dimensional(3D)digital core analysis and numerical simulations,followed by data-driven modeling via machine learning(ML)techniques.Key data-driven strategies,including feature selection and hyperparameter tuning,are employed to improve model performance.We propose and evaluate twelve data-driven models,including multilayer perceptron(MLP),random forest(RF),and hybrid methods.The results demonstrate that the ML model based on the RF algorithm achieves the highest accuracy and best generalization capability in predicting permeability.This method enables rapid estimation of coal permeability by inputting two-dimensional(2D)computed tomography images or parameters of the microscopic fracture structure,thereby providing an accurate and efficient means of permeability prediction.展开更多
Existing sandstone rock structure evaluation methods rely on visual inspection,with low efficiency,semi-quantitative analysis of roundness,and inability to perform classified statistics in particle size analysis.This ...Existing sandstone rock structure evaluation methods rely on visual inspection,with low efficiency,semi-quantitative analysis of roundness,and inability to perform classified statistics in particle size analysis.This study presents an intelligent evaluation method for sandstone rock structure based on the Segment Anything Model(SAM).By developing a lightweight SAM fine-tuning method with rank-decomposition matrix adapters,a multispectral rock particle segmentation model named CoreSAM is constructed,which achieves rock particle edge extraction and type identification.Building upon this,we propose a comprehensive quantitative evaluation system for rock structure,assessing parameters including particle size,sorting,roundness,particle contact and cementation types.The experimental results demonstrate that CoreSAM outperforms existing methods in rock particle segmentation accuracy while showing excellent generalization across different image types such as CT scans and core photographs.The proposed method enables full-sample,classified particle size analysis and quantitative characterization of parameters like roundness,advancing reservoir evaluation towards more precise,quantitative,intuitive,and comprehensive development.展开更多
Structure-type rockbursts frequently occur in deep tunnels,with structural planes and stress conditions being critical factors in their formation.In this study,we utilized specially developed analogous materials that ...Structure-type rockbursts frequently occur in deep tunnels,with structural planes and stress conditions being critical factors in their formation.In this study,we utilized specially developed analogous materials that exhibit the high brittleness and strength characteristics of deep hard rock to construct physical models representing different types of structural planes,including composite,exposed,non-exposed,and throughgoing structural planes.Physical simulation experiments were conducted on structuretype rockbursts in deep horseshoe-shaped tunnels,focusing on strain differentiation characteristics,critical triggering conditions,critical crack opening displacement,the incubation process,the reduction effects of structural planes on failure intensity,and formation mechanisms.These experiments were complemented by acoustic and optical monitoring,as well as discrete element numerical simulations,to provide a comprehensive analysis.The results revealed that the most significant strain heterogeneity in the surrounding rock occurs at the tip of the structural plane along the tunnel's minimum principal stress direction,driven by the combined effects of tensile and shear forces.We quantitatively determined the critical stress and strain conditions for structure-type rockbursts and evaluated the intensity of rockbursts induced by different structural planes using critical crack opening displacement(COD)values,the uniformity coefficient,and the curvature coefficient.Analysis of acoustic emission events,including frequency,amplitude,and b-value,indicated that the macro-fracture process is governed by both the principal stress differential and the characteristics of the structural plane.Furthermore,using the bearing capacity reduction coefficient,we found that exposed structural planes have the most significant weakening effect on rock mass strength,followed by non-exposed and throughgoing structural planes.The analysis of average frequency(AF)and rise angle(RA)parameters revealed a close correlation between the failure modes of structure-type rockbursts,the rock mass structure,and the stress levels.These findings provide critical theoretical support for the prediction and prevention of structure-type rockburst disasters.展开更多
To mill fine and well-defined micro-dimpled structures,a machining manner of spiral trajectory tool reciprocating motion,where the tool repeats the process of‘feed milling–retract–cutting feed–feed milling again’...To mill fine and well-defined micro-dimpled structures,a machining manner of spiral trajectory tool reciprocating motion,where the tool repeats the process of‘feed milling–retract–cutting feed–feed milling again’along the spiral trajectory,was proposed.From the kinematics analysis,it is found that the machining quality of micro-dimpled structures is highly dependent on the machining trajectory using spiral trajectory tool reciprocating motion.To reveal this causation,simulation modelling and experimental studies were carried out.A simulation model was developed to quantitatively and qualitatively investigate the influence of the trajectory discretization strategies(constant-angle and constant-arc length)and parameters(discrete angle,discrete arc length,and pitch)on surface texture and residual height of micro-dimpled structures.Subsequently,micro-dimpled structures were milled under different trajectory discretization strategies and parameters with spiral trajectory tool reciprocating motion.A comprehensive comparison between the milled results and simulation analysis was made based on geometry accuracy,surface morphology and surface roughness of milled dimples.Meanwhile,the errors and factors affecting the above three aspects were analyzed.The results demonstrate both the feasibility of the established simulation model and the machining capability of this machining way in milling high-quality micro-dimpled structures.Spiral trajectory tool reciprocating motion provides a new machining way for milling micro-dimpled structures and micro-dimpled functional surfaces.And an appropriate machining trajectory can be generated based on the optimized trajectory parameters,thus contributing to the improvement of machining quality and efficiency.展开更多
The optimum models of harvesting yield and net profits of large diameter trees for broadleaved forest were developed, of which include matrix growth sub-model, harvesting cost and wood price sub-models, based on the d...The optimum models of harvesting yield and net profits of large diameter trees for broadleaved forest were developed, of which include matrix growth sub-model, harvesting cost and wood price sub-models, based on the data from Hongshi Forestry Bureau, in Changbai Mountain region, Jilin Province, China. The data were measured in 232 permanent sample plots. With the data of permanent sample plots, the parameters of transition probability and ingrowth models were estimated, and some models were compared and partly modified. During the simulation of stand structure, four factors such as largest diameter residual tree （LDT）, the ratio of the number of trees in a given diameter class to those in the next larger diameter class （q）, residual basal area （RBA） and selective cutting cycle （C） were considered. The simulation results showed that the optimum stand structure parameters for large diameter trees are as follows： q is 1.2, LDT is 46cm, RBA is larger than 26 m^2 and selective cutting cycle time （C） is between 10 and 20 years.展开更多
According to the failure characteristics of aircraft structure, a delay-time model is an effective method to optimize maintenance for aircraft structure. To imitate the practical situation as much as possible, imperfe...According to the failure characteristics of aircraft structure, a delay-time model is an effective method to optimize maintenance for aircraft structure. To imitate the practical situation as much as possible, imperfect inspections, thresholds and repeated intervals are concerned in delay-time models. Since the suggestion by the existing delay-time models that the inspections are implemented in an infinite time span lacks practical value, a de- lay-time model with imperfect inspection within a finite time span is proposed. In the model, the nonhomogenous Poisson process is adopted to obtain the renewal probabilities between two different successive inspections on de- fects or failures. An algorithm is applied based on the Nelder-Mead downhill simplex method to solve the model. Finally, a numerical example proves the validity and effectiveness of the model.展开更多
To design the control system for some homing missile so that the autopilot can transfer guidance command correctly and be robust to disturbances, such as the measurement noises and parameter variation caused by areody...To design the control system for some homing missile so that the autopilot can transfer guidance command correctly and be robust to disturbances, such as the measurement noises and parameter variation caused by areodynamic floating. The model reference adaptive control was combined with the variable structure control to design a model reference variable structure (MRVS) control system whose control structure is simple and can be realized easily. The simulation results indicate that MRVS can complete the task of transferring guidance command and suppress the distrubances effectively.展开更多
In order to find the main factors that influence the urban traffic structure,a relational model between the travelers＇ characteristics and the trip mode choice is built.The data of urban residents＇ characteristics a...In order to find the main factors that influence the urban traffic structure,a relational model between the travelers＇ characteristics and the trip mode choice is built.The data of urban residents＇ characteristics are obtained from statistical data,while the trip mode split data is collected through a trip survey in Bengbu.In addition,the discrete choice model is adopted to build the functional relationship between the mode choice and the travelers＇ personal characteristics,as well as family characteristics and trip characteristics.The model shows that the relationship between the mode split and the personal,as well as family and trip characteristics is stable and changes little as the time changes.Deduced by the discrete model,the mode split result is relatively accurate and can be feasibly used for trip mode structure forecasts.Furthermore,the proposed model can also contribute to find the key influencing factors on trip mode choice,and restructure or optimize the urban trip mode structure.展开更多
As the core content of pragmatic translation teaching research,pragmatic translation skill is closely correlated with translation technique and operation field.Viewed from the current English teaching situation in col...As the core content of pragmatic translation teaching research,pragmatic translation skill is closely correlated with translation technique and operation field.Viewed from the current English teaching situation in colleges and universities,translation skill is not cultivated as an independent language competence.Moreover,its research is insufficient.On account of this,the author first gives an introduction to pragmatic translation skill and pragmatic translation skill structure model in this paper.On this basis,the author also analyzes the application of pragmatic translation skill structure model in translation teaching.展开更多
This paper aims to improve the accuracy and applicability of gas diffusion mathematical models from coal particles. Firstly, a new constitutive model for gas diffusion from coal particles with tri-disperse pore struct...This paper aims to improve the accuracy and applicability of gas diffusion mathematical models from coal particles. Firstly, a new constitutive model for gas diffusion from coal particles with tri-disperse pore structure is constructed by considering the difference in characteristics between soft coal and hard coal.The analytical solution is then derived, that is, the quantitative relationship between gas diffusion rate(Qt/Q_∞) and diffusion time(t), The pore structure parameters of soft coal and hard coal from Juji coal mine are determined. Gas diffusion rules are numerically calculated and investigated by physical simulation methods. Lastly, the applicability of this model is verified. The results show that the homogeneous model only applies to the gas diffusion process of hard coal during the initial 10 min. The calculation results from this model and the physical experimental results of soft coal and hard coal are nearly identical during the initial 30 min.展开更多
Base isolation can effectively reduce the seismic forces on a superstructure,particularly in lowto medium-rise buildings.However,under strong near-fault ground motions,pounding may occur at the isolation level between...Base isolation can effectively reduce the seismic forces on a superstructure,particularly in lowto medium-rise buildings.However,under strong near-fault ground motions,pounding may occur at the isolation level between the baseisolated building(BIB)and its surrounding retaining walls.To effectively investigate the behavior of the BIB pounding with adjacent structures,after assessing some commonly used impact models,a modified Kelvin impact model is proposed in this paper.Relevant parameters in the modified Kelvin model are theoretically derived and numerically verified through a simple pounding case.At the same time,inelasticity of the isolated superstructure is introduced in order to accurately evaluate the potential damage to the superstructure caused by the pounding of the BIB with adjacent structures.The reliability of the modified Kelvin impact model is validated through numerical comparisons with other impact models.However,the difference between the numerical results from the various impact analytical models is not significant.Many numerical simulations of BIBs are conducted to investigate the influence of various design parameters and conditions on the peak inter-story drifts and floor accelerations during pounding.It is shown that pounding can substantially increase floor accelerations,especially at the ground floor where impacts occur.Higher modes of vibration are excited during poundings,increasing the inter-story drifts instead of keeping a nearly rigid-body motion of the superstructure.Furthermore,higher ductility demands can be imposed on lower floors of the superstructure.Moreover,impact stiffness seems to play a significant role in the acceleration response at the isolation level and the inter-story drifts of lower floors of the superstructure.Finally,the numerical results show that excessive flexibility of the isolation system used to minimize the floor accelerations may cause the BIB to be more susceptible to pounding under a limited seismic gap.展开更多
Located at the northwest continental slope of the South China Sea, the Qiongdongnan Basin bears valley-shaped bathymetry deepening toward east. It is separated from the Yinggehai Basin through NW-trending Indo-China-R...Located at the northwest continental slope of the South China Sea, the Qiongdongnan Basin bears valley-shaped bathymetry deepening toward east. It is separated from the Yinggehai Basin through NW-trending Indo-China-Red River shear zone, and connected with NW subsea basin through the Xisha Trough. Along with the rapid progress of the deepwater exploration, large amounts of high resolution geophysical and geological data were accumulated. Scientific researches about deepwater basins kept revealing brand new tectonic and sedimentary discoveries. In order to summarize the structural features and main controlling factors of the deepwater Qiongdongnan Basin, a series of researches on basin architecture, fault activities, tectonic deformation and evolution were carried out. In reference to analogue modeling experiments, a tectonic situation and a basin formation mechanism were discussed. The researches indicate that：the northern boundary of the Qiongdongnan Basin is strongly controlled by No. 2 fault. The overlapping control of two stress fields from the east and the west made the central depression zone extremely thinned. Combined with the changed stress field, the segmentation of a preexisting weakness zone made the sags in the east experiencing different rifting histories from the west ones. The NE-trending west segment of the Qiongdongnan Basin experienced strong rifting during Eocene, while the roughly EW-trending sags in the east segment show strong rifting during late Eocene and early Oligocene. Local structures such as NW-trending basal fault and inherited uplifts controlled the lateral segmentation. So first order factors such as regional stress field and preexisting weakness zone controlled the basin zonation, while the second order factors determined the segmentation from east to west.展开更多
This paper discusses the enrichment and depletion regularities for porphyry coppermolybdenum ore deposits in different regions and varied deposit genetic types in the same area, taking three porphyry copper-molybdenum...This paper discusses the enrichment and depletion regularities for porphyry coppermolybdenum ore deposits in different regions and varied deposit genetic types in the same area, taking three porphyry copper-molybdenum ore deposits （i.e., the Chengmenshan in Jiangxi, Wunugetushan in Inner Mongolia, Baishantang in Gansu） and two copper deposits in Gansu Province （the Huitongshan skarn deposit and Gongpoquan composite deposit） as case studies. The results show that porphyry Cu-Mo deposits or skarn copper deposits include both enrichment of the ore-forming elements and associated elements, and depletion of some lithophile dispersed elements, rare earth elements （REE） and some major elements. And the depleted elements vary with deposits, having generality and their own features. On a deposit scale, the positive anomalies of enriched elements and negative anomalies of depleted elements follow in a sequence to comprise regular anomaly models of spatial structures. The exploration in the Tongchang deposit in Jiangxi and Huitongshan deposit in Gansu suggests that anomaly models play a key role in the identification of mineral occurrences and deposits compared to one single enriched element anomaly. And the anomaly models exert a critical effect on the optimization of prospecting targets and their potential evaluation.展开更多
Implementation of an opposing jet in design of a hypersonic blunt body significantly modifies the external flowfield and yields a considerable reduction in the aerodynamic drag.This study aims to investigate the effec...Implementation of an opposing jet in design of a hypersonic blunt body significantly modifies the external flowfield and yields a considerable reduction in the aerodynamic drag.This study aims to investigate the effects of flowfield modeling parameters of injection and freestream on the flow structure and aerodynamics of a blunt body with an opposing jet in hypersonic flow.Reynolds-Averaged Navier-Stokes(RANS)equations with a Shear Stress Transport(SST)turbulence model are employed to simulate the intricate jet flow interaction.Through utilizing a Non-Intrusive Polynomial Chaos(NIPC)method to construct surrogates,a functional relation is established between input modeling parameters and output flowfield and aerodynamic quantities in concern.Sobol indices in sensitivity analysis are introduced to represent the relative contribution of each parameter.It is found that variations in modeling parameters produce large variations in the flow structure and aerodynamics.The jet-to-freestream total-pressure ratio,jet Mach number,and freestream Mach number are the major contributors to variation in surface pressure,demonstrating an evident location-dependent behavior.The penetration length of injection,reattachment angle of the shear layer,and aerodynamic drag are also most sensitive to the three crucial parameters above.In comparison,the contributions of freestream temperature,freestream density,and jet total temperature are nearly negligible.展开更多
Using Fourier inversion transform, P.D.E. and Feynman-Kac formula, the closedform solution for price on European call option is given in a double exponential jump-diffusion model with two different market structure ri...Using Fourier inversion transform, P.D.E. and Feynman-Kac formula, the closedform solution for price on European call option is given in a double exponential jump-diffusion model with two different market structure risks that there exist CIR stochastic volatility of stock return and Vasicek or CIR stochastic interest rate in the market. In the end, the result of the model in the paper is compared with those in other models, including BS model with numerical experiment. These results show that the double exponential jump-diffusion model with CIR-market structure risks is suitable for modelling the real-market changes and very useful.展开更多
Despite the great efforts dedicated to metallic glasses （MGs）, their structure still remains a mystery to be understood. With comparison to the existing mJciomechanical models, such as the free-volume and shear tran...Despite the great efforts dedicated to metallic glasses （MGs）, their structure still remains a mystery to be understood. With comparison to the existing mJciomechanical models, such as the free-volume and shear transformation zone （STZ） models, we first discuss in this article our recently proposed ＇core-shell＇ model, which contains a solid-like matrix and liquid-like inclusions. This serves as the theoretical basis to understand the structural heterogeneity in MGs in our analytical framework. After that, a scanning ultrafast nanoindentation technique is used to map out the structure heterogeneity in a Zr-based bulk metallic glass （BMG）. With these ongoing research efforts, we hope that more research work could be stimulated in the pursuit of the structure-property relation in MGs.展开更多
基金Project supported by the National Defense Technology Foundation Under the State Administration of Science,Technology,and Industry for National Defense of China(No.JSZL2022213A001)the Special Funds for Basic Research in Central Universities of China(No.HYGJZN202322)。
文摘The bolted flange structure finds significant applications in fields such as aerospace,shipbuilding,and pipeline transportation.The investigation of its dynamic characteristics has consistently been a focal point for researchers;however,there remains a deficiency in the development of robust analytical models.This paper introduces a novel analytical model based on the finite element methods and the Timoshenko beam theory to accurately simulate the bolted flange structure.The stiffness,mass,damping,and inertia matrices of the rotor system are individually derived,and the dynamic equation is subsequently formulated.The model’s validity and accuracy are validated through both the experimental testing and the finite element analysis.This study aims to elucidate the relationship between the external loads and the influence of the geometric configuration on the stiffness and contact behavior of the bolted flange structure,thereby enabling a thorough and precise prediction of the static and dynamic load transfer pathways,as well as the distribution of vibrational energy within the structure,while also facilitating the incorporation of friction and slip effects.Simultaneously,this work provides a foundational framework for the optimization design of bolted flange structures,addressing the factors such as the number,size,and geometric distribution of bolts.
基金The National Natural Science Foundation of China(No.52078427).
文摘To ensure the operational safety of railways in the landslide-prone areas of mountainous regions,a large-scale model test and numerical simulation were conducted to study the bending moment distribution,internal force distribution,deformation development,and crack propagation characteristics of a framed anti-sliding structure(FAS)under landslide thrust up to the point of failure.Results show that the maximum bending moment and its increase rate in the fore pile are greater than those in the rear pile,with the maximum bending moment of the fore pile approximately 1.1 times that of the rear pile.When the FAS fails,the displacement at the top of the fore pile is significantly greater,about 1.27 times that of the rear pile in the experiment.Major cracks develop at locations corresponding to the peak bending moments.Small transverse cracks initially appear on the upper surface at the intersection between the primary beam and rear pile and then spread to the side of the structure.At the failure stage,major cracks are observed at the pil-beam intersections and near the anchor points.Strengthening flexural stiffness at intersections where major cracks occur can improve the overall thrust-deformation coordination of the FAS,thereby maximizing its performance.
基金National Natural Science Foundation of China(22073023)Natural Science Foundation of Henan Province(242300421134)+1 种基金the Young Backbone Teacher in Colleges and Universities of Henan Province(2021GGJS020)Foundation of State Key Laboratory of Antiviral Drugs。
文摘The acetylpolyamine oxidase(APAO),spermine oxidase(SMO),and spermidine/spermine N1-acetyltransferase(SSAT)are pivotal enzymes in polyamine metabolism,exerting direct influence on polyamine homeostasis regulation.Dysfunctions in these enzymes are intricately linked to inflammatory diseases and cancers.Establishing their three-dimensional structures is essential for exploring enzymatic catalytic mechanisms and designing inhibitors at the atomic level.This article primarily assesses the precision of AlphaFold2 and molecular dynamics simulations in determining the three-dimensional structures of these enzymes,utilizing protein conformation rationality assessment,residue correlation matrix,and other techniques.This provides robust models for subsequent polyamine catabolic metabolism calculations and offers valuable insights for modeling proteins that have yet to acquire crystal structures.
文摘Beach groynes are structures for erosion protection along sandy coasts near inlets and can reduce the coastal erosion substantially,but open groynes cannot stop erosion completely because sand can be removed from the groyne compartments by cross-shore processes.Beach groynes should be designed with sufficient bypassing of sand to minimise erosion.Regular beach maintenance is required to keep a sufficient beach width for recreational purposes.The effectiveness of groyne compartments can be significantly improved by using T-head groynes or by using a submerged sill or breakwater in between the groynes.An economic evaluation shows that the beach maintenance costs over 50 years may be substantially higher than the construction costs of a submerged breakwater.An important parameter to be studied is the longshore transport,which requires detailed information of the wave climate,preferably based on measured data(offshore buoys)in combination with deep water wave modelling.Various models have been used to determine the net longshore sand transport and coastline changes.The design of groynes to reduce coastal erosion is illustrated by three field cases(Atlantic coast near Soulac,France;Lagos coast,Nigeria and Black Sea coast,Romania).These example cases show that beach groynes are effective structures,but sufficient bypassing of longshore sand transport is essential to minimise erosion.Regular beach fills in the groyne compartments may be required at high-energy(exposed)coasts.A submerged or emerged breakwater can be built between the groynes to protect the beach in the groyne compartments against erosion by cross-shore processes.
基金supported by the Zhejiang Provincial Natural Science Foundation of China(Grant No.LY23E040001)Fundamental Research Funding Project of Zhejiang Province,China(Project Category A,Grant No.2022YW06)National Key R&D Program of China(Grant No.2023YFF0614902).
文摘Accurate prediction of coal reservoir permeability is crucial for engineering applications,including coal mining,coalbed methane(CBM)extraction,and carbon storage in deep unmineable coal seams.Owing to the inherent heterogeneity and complex internal structure of coal,a well-established method for predicting permeability based on microscopic fracture structures remains elusive.This paper presents a novel integrated approach that leverages the intrinsic relationship between microscopic fracture structure and permeability to construct a predictive model for coal permeability.The proposed framework encompasses data generation through the integration of three-dimensional(3D)digital core analysis and numerical simulations,followed by data-driven modeling via machine learning(ML)techniques.Key data-driven strategies,including feature selection and hyperparameter tuning,are employed to improve model performance.We propose and evaluate twelve data-driven models,including multilayer perceptron(MLP),random forest(RF),and hybrid methods.The results demonstrate that the ML model based on the RF algorithm achieves the highest accuracy and best generalization capability in predicting permeability.This method enables rapid estimation of coal permeability by inputting two-dimensional(2D)computed tomography images or parameters of the microscopic fracture structure,thereby providing an accurate and efficient means of permeability prediction.
基金Supported by the National Natural Science Foundation of China(42372175,72088101)PetroChina Science and Technology Project of(2023DJ84)Basic Research Cooperation Project between China National Petroleum Corporation and Peking University.
文摘Existing sandstone rock structure evaluation methods rely on visual inspection,with low efficiency,semi-quantitative analysis of roundness,and inability to perform classified statistics in particle size analysis.This study presents an intelligent evaluation method for sandstone rock structure based on the Segment Anything Model(SAM).By developing a lightweight SAM fine-tuning method with rank-decomposition matrix adapters,a multispectral rock particle segmentation model named CoreSAM is constructed,which achieves rock particle edge extraction and type identification.Building upon this,we propose a comprehensive quantitative evaluation system for rock structure,assessing parameters including particle size,sorting,roundness,particle contact and cementation types.The experimental results demonstrate that CoreSAM outperforms existing methods in rock particle segmentation accuracy while showing excellent generalization across different image types such as CT scans and core photographs.The proposed method enables full-sample,classified particle size analysis and quantitative characterization of parameters like roundness,advancing reservoir evaluation towards more precise,quantitative,intuitive,and comprehensive development.
基金supported by the National Natural Science Foundation of China(Grant Nos.42307241 and 42107211)the State Key Laboratory of Geohazard Prevention and Geoenvironment Protection Independent Research Project(Grant No.SKLGP2022Z008).
文摘Structure-type rockbursts frequently occur in deep tunnels,with structural planes and stress conditions being critical factors in their formation.In this study,we utilized specially developed analogous materials that exhibit the high brittleness and strength characteristics of deep hard rock to construct physical models representing different types of structural planes,including composite,exposed,non-exposed,and throughgoing structural planes.Physical simulation experiments were conducted on structuretype rockbursts in deep horseshoe-shaped tunnels,focusing on strain differentiation characteristics,critical triggering conditions,critical crack opening displacement,the incubation process,the reduction effects of structural planes on failure intensity,and formation mechanisms.These experiments were complemented by acoustic and optical monitoring,as well as discrete element numerical simulations,to provide a comprehensive analysis.The results revealed that the most significant strain heterogeneity in the surrounding rock occurs at the tip of the structural plane along the tunnel's minimum principal stress direction,driven by the combined effects of tensile and shear forces.We quantitatively determined the critical stress and strain conditions for structure-type rockbursts and evaluated the intensity of rockbursts induced by different structural planes using critical crack opening displacement(COD)values,the uniformity coefficient,and the curvature coefficient.Analysis of acoustic emission events,including frequency,amplitude,and b-value,indicated that the macro-fracture process is governed by both the principal stress differential and the characteristics of the structural plane.Furthermore,using the bearing capacity reduction coefficient,we found that exposed structural planes have the most significant weakening effect on rock mass strength,followed by non-exposed and throughgoing structural planes.The analysis of average frequency(AF)and rise angle(RA)parameters revealed a close correlation between the failure modes of structure-type rockbursts,the rock mass structure,and the stress levels.These findings provide critical theoretical support for the prediction and prevention of structure-type rockburst disasters.
基金co-supported the National Natural Science Foundation of China(No.52235010)the Heilongjiang Postdoctoral Fund(No.LBH-Z22136)the New Era Longjiang Excellent Master and Doctoral Dissertation Fund(No.LJYXL2022-057).
文摘To mill fine and well-defined micro-dimpled structures,a machining manner of spiral trajectory tool reciprocating motion,where the tool repeats the process of‘feed milling–retract–cutting feed–feed milling again’along the spiral trajectory,was proposed.From the kinematics analysis,it is found that the machining quality of micro-dimpled structures is highly dependent on the machining trajectory using spiral trajectory tool reciprocating motion.To reveal this causation,simulation modelling and experimental studies were carried out.A simulation model was developed to quantitatively and qualitatively investigate the influence of the trajectory discretization strategies(constant-angle and constant-arc length)and parameters(discrete angle,discrete arc length,and pitch)on surface texture and residual height of micro-dimpled structures.Subsequently,micro-dimpled structures were milled under different trajectory discretization strategies and parameters with spiral trajectory tool reciprocating motion.A comprehensive comparison between the milled results and simulation analysis was made based on geometry accuracy,surface morphology and surface roughness of milled dimples.Meanwhile,the errors and factors affecting the above three aspects were analyzed.The results demonstrate both the feasibility of the established simulation model and the machining capability of this machining way in milling high-quality micro-dimpled structures.Spiral trajectory tool reciprocating motion provides a new machining way for milling micro-dimpled structures and micro-dimpled functional surfaces.And an appropriate machining trajectory can be generated based on the optimized trajectory parameters,thus contributing to the improvement of machining quality and efficiency.
基金This paper was supported by National Strategy Key Project, Research and Paradigm on Ecological Harvesting and Regeneration Tech-nique for Northeast Natural Forest (2001BA510B07-02)
文摘The optimum models of harvesting yield and net profits of large diameter trees for broadleaved forest were developed, of which include matrix growth sub-model, harvesting cost and wood price sub-models, based on the data from Hongshi Forestry Bureau, in Changbai Mountain region, Jilin Province, China. The data were measured in 232 permanent sample plots. With the data of permanent sample plots, the parameters of transition probability and ingrowth models were estimated, and some models were compared and partly modified. During the simulation of stand structure, four factors such as largest diameter residual tree （LDT）, the ratio of the number of trees in a given diameter class to those in the next larger diameter class （q）, residual basal area （RBA） and selective cutting cycle （C） were considered. The simulation results showed that the optimum stand structure parameters for large diameter trees are as follows： q is 1.2, LDT is 46cm, RBA is larger than 26 m^2 and selective cutting cycle time （C） is between 10 and 20 years.
基金Supported by the National Natural Science Foundation of China(61079013)the Natural Science Fund Project in Jiangsu Province(BK2011737)~~
文摘According to the failure characteristics of aircraft structure, a delay-time model is an effective method to optimize maintenance for aircraft structure. To imitate the practical situation as much as possible, imperfect inspections, thresholds and repeated intervals are concerned in delay-time models. Since the suggestion by the existing delay-time models that the inspections are implemented in an infinite time span lacks practical value, a de- lay-time model with imperfect inspection within a finite time span is proposed. In the model, the nonhomogenous Poisson process is adopted to obtain the renewal probabilities between two different successive inspections on de- fects or failures. An algorithm is applied based on the Nelder-Mead downhill simplex method to solve the model. Finally, a numerical example proves the validity and effectiveness of the model.
文摘To design the control system for some homing missile so that the autopilot can transfer guidance command correctly and be robust to disturbances, such as the measurement noises and parameter variation caused by areodynamic floating. The model reference adaptive control was combined with the variable structure control to design a model reference variable structure (MRVS) control system whose control structure is simple and can be realized easily. The simulation results indicate that MRVS can complete the task of transferring guidance command and suppress the distrubances effectively.
基金The National Natural Science Foundation of China (No.50738001,51078086)
文摘In order to find the main factors that influence the urban traffic structure,a relational model between the travelers＇ characteristics and the trip mode choice is built.The data of urban residents＇ characteristics are obtained from statistical data,while the trip mode split data is collected through a trip survey in Bengbu.In addition,the discrete choice model is adopted to build the functional relationship between the mode choice and the travelers＇ personal characteristics,as well as family characteristics and trip characteristics.The model shows that the relationship between the mode split and the personal,as well as family and trip characteristics is stable and changes little as the time changes.Deduced by the discrete model,the mode split result is relatively accurate and can be feasibly used for trip mode structure forecasts.Furthermore,the proposed model can also contribute to find the key influencing factors on trip mode choice,and restructure or optimize the urban trip mode structure.
文摘As the core content of pragmatic translation teaching research,pragmatic translation skill is closely correlated with translation technique and operation field.Viewed from the current English teaching situation in colleges and universities,translation skill is not cultivated as an independent language competence.Moreover,its research is insufficient.On account of this,the author first gives an introduction to pragmatic translation skill and pragmatic translation skill structure model in this paper.On this basis,the author also analyzes the application of pragmatic translation skill structure model in translation teaching.
基金the National Natural Science Foundation of China(Nos.51374095 and 51404099)the Program for Innovative Research Team in University of Ministry of Education of China(IRT_16R22)+1 种基金the Henan Provincial Key Scientific and Technological Project(No.092102310314)China Scholarship Council
文摘This paper aims to improve the accuracy and applicability of gas diffusion mathematical models from coal particles. Firstly, a new constitutive model for gas diffusion from coal particles with tri-disperse pore structure is constructed by considering the difference in characteristics between soft coal and hard coal.The analytical solution is then derived, that is, the quantitative relationship between gas diffusion rate(Qt/Q_∞) and diffusion time(t), The pore structure parameters of soft coal and hard coal from Juji coal mine are determined. Gas diffusion rules are numerically calculated and investigated by physical simulation methods. Lastly, the applicability of this model is verified. The results show that the homogeneous model only applies to the gas diffusion process of hard coal during the initial 10 min. The calculation results from this model and the physical experimental results of soft coal and hard coal are nearly identical during the initial 30 min.
基金National Natural Science Foundation of China Under Grant No.50778077 and 50878093
文摘Base isolation can effectively reduce the seismic forces on a superstructure,particularly in lowto medium-rise buildings.However,under strong near-fault ground motions,pounding may occur at the isolation level between the baseisolated building(BIB)and its surrounding retaining walls.To effectively investigate the behavior of the BIB pounding with adjacent structures,after assessing some commonly used impact models,a modified Kelvin impact model is proposed in this paper.Relevant parameters in the modified Kelvin model are theoretically derived and numerically verified through a simple pounding case.At the same time,inelasticity of the isolated superstructure is introduced in order to accurately evaluate the potential damage to the superstructure caused by the pounding of the BIB with adjacent structures.The reliability of the modified Kelvin impact model is validated through numerical comparisons with other impact models.However,the difference between the numerical results from the various impact analytical models is not significant.Many numerical simulations of BIBs are conducted to investigate the influence of various design parameters and conditions on the peak inter-story drifts and floor accelerations during pounding.It is shown that pounding can substantially increase floor accelerations,especially at the ground floor where impacts occur.Higher modes of vibration are excited during poundings,increasing the inter-story drifts instead of keeping a nearly rigid-body motion of the superstructure.Furthermore,higher ductility demands can be imposed on lower floors of the superstructure.Moreover,impact stiffness seems to play a significant role in the acceleration response at the isolation level and the inter-story drifts of lower floors of the superstructure.Finally,the numerical results show that excessive flexibility of the isolation system used to minimize the floor accelerations may cause the BIB to be more susceptible to pounding under a limited seismic gap.
基金The Major National Science and Technology Programs of China under contract No.2011ZX05025-003-005the Joint Program of the National Science Foundation and Guangdong Province under contract No.U1301233
文摘Located at the northwest continental slope of the South China Sea, the Qiongdongnan Basin bears valley-shaped bathymetry deepening toward east. It is separated from the Yinggehai Basin through NW-trending Indo-China-Red River shear zone, and connected with NW subsea basin through the Xisha Trough. Along with the rapid progress of the deepwater exploration, large amounts of high resolution geophysical and geological data were accumulated. Scientific researches about deepwater basins kept revealing brand new tectonic and sedimentary discoveries. In order to summarize the structural features and main controlling factors of the deepwater Qiongdongnan Basin, a series of researches on basin architecture, fault activities, tectonic deformation and evolution were carried out. In reference to analogue modeling experiments, a tectonic situation and a basin formation mechanism were discussed. The researches indicate that：the northern boundary of the Qiongdongnan Basin is strongly controlled by No. 2 fault. The overlapping control of two stress fields from the east and the west made the central depression zone extremely thinned. Combined with the changed stress field, the segmentation of a preexisting weakness zone made the sags in the east experiencing different rifting histories from the west ones. The NE-trending west segment of the Qiongdongnan Basin experienced strong rifting during Eocene, while the roughly EW-trending sags in the east segment show strong rifting during late Eocene and early Oligocene. Local structures such as NW-trending basal fault and inherited uplifts controlled the lateral segmentation. So first order factors such as regional stress field and preexisting weakness zone controlled the basin zonation, while the second order factors determined the segmentation from east to west.
基金financially supported by the research special fund of public service sector from the Ministry of Land and Resources (No. 201111008)
文摘This paper discusses the enrichment and depletion regularities for porphyry coppermolybdenum ore deposits in different regions and varied deposit genetic types in the same area, taking three porphyry copper-molybdenum ore deposits （i.e., the Chengmenshan in Jiangxi, Wunugetushan in Inner Mongolia, Baishantang in Gansu） and two copper deposits in Gansu Province （the Huitongshan skarn deposit and Gongpoquan composite deposit） as case studies. The results show that porphyry Cu-Mo deposits or skarn copper deposits include both enrichment of the ore-forming elements and associated elements, and depletion of some lithophile dispersed elements, rare earth elements （REE） and some major elements. And the depleted elements vary with deposits, having generality and their own features. On a deposit scale, the positive anomalies of enriched elements and negative anomalies of depleted elements follow in a sequence to comprise regular anomaly models of spatial structures. The exploration in the Tongchang deposit in Jiangxi and Huitongshan deposit in Gansu suggests that anomaly models play a key role in the identification of mineral occurrences and deposits compared to one single enriched element anomaly. And the anomaly models exert a critical effect on the optimization of prospecting targets and their potential evaluation.
文摘Implementation of an opposing jet in design of a hypersonic blunt body significantly modifies the external flowfield and yields a considerable reduction in the aerodynamic drag.This study aims to investigate the effects of flowfield modeling parameters of injection and freestream on the flow structure and aerodynamics of a blunt body with an opposing jet in hypersonic flow.Reynolds-Averaged Navier-Stokes(RANS)equations with a Shear Stress Transport(SST)turbulence model are employed to simulate the intricate jet flow interaction.Through utilizing a Non-Intrusive Polynomial Chaos(NIPC)method to construct surrogates,a functional relation is established between input modeling parameters and output flowfield and aerodynamic quantities in concern.Sobol indices in sensitivity analysis are introduced to represent the relative contribution of each parameter.It is found that variations in modeling parameters produce large variations in the flow structure and aerodynamics.The jet-to-freestream total-pressure ratio,jet Mach number,and freestream Mach number are the major contributors to variation in surface pressure,demonstrating an evident location-dependent behavior.The penetration length of injection,reattachment angle of the shear layer,and aerodynamic drag are also most sensitive to the three crucial parameters above.In comparison,the contributions of freestream temperature,freestream density,and jet total temperature are nearly negligible.
基金Supported by the NNSF of China(40675023)the PHD Foundation of Guangxi Normal University.
文摘Using Fourier inversion transform, P.D.E. and Feynman-Kac formula, the closedform solution for price on European call option is given in a double exponential jump-diffusion model with two different market structure risks that there exist CIR stochastic volatility of stock return and Vasicek or CIR stochastic interest rate in the market. In the end, the result of the model in the paper is compared with those in other models, including BS model with numerical experiment. These results show that the double exponential jump-diffusion model with CIR-market structure risks is suitable for modelling the real-market changes and very useful.
基金support provided by City University of Hong Kong (CityU) through the start-up grant for newly recruited faculty members (Project No. 7200303)the research of C.T. Liu is also supported by CityU (Project No. CityU117612)
文摘Despite the great efforts dedicated to metallic glasses （MGs）, their structure still remains a mystery to be understood. With comparison to the existing mJciomechanical models, such as the free-volume and shear transformation zone （STZ） models, we first discuss in this article our recently proposed ＇core-shell＇ model, which contains a solid-like matrix and liquid-like inclusions. This serves as the theoretical basis to understand the structural heterogeneity in MGs in our analytical framework. After that, a scanning ultrafast nanoindentation technique is used to map out the structure heterogeneity in a Zr-based bulk metallic glass （BMG）. With these ongoing research efforts, we hope that more research work could be stimulated in the pursuit of the structure-property relation in MGs.
