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Fingerprint Patterns in Students with Learning Disability:Evidence of Sexual Dimorphism and Potential for Diagnosis in a Nigerian Population
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作者 Ndubuisi Paris Obi Izuchukwu Azuka Okafor Chijioke Okeke 《Journal of Forensic Science and Medicine》 2023年第2期153-161,I0001-I0005,共14页
This study assessed the sex-based relationship and prediction pattern between fingerprint patterns,ridge counts,and learning disability(LD).This cross-sectional study recruited 300 students(150 LD and 150 non-LD)aged ... This study assessed the sex-based relationship and prediction pattern between fingerprint patterns,ridge counts,and learning disability(LD).This cross-sectional study recruited 300 students(150 LD and 150 non-LD)aged between 3 and 29 years.The fingerprint patterns(arch,whorl,ulnar loop,and radial loop)and the ridge count:total finger ridge count(TFRC),absolute ridge count(ARC),ulnar ridge count(URC),and radial ridge count(RRC)were accessed.Students with LD showed a significantly higher whorl and a significantly lower ulnar loop than students without LD.There is a significant association of whorl pattern in the first right finger of subjects with LD compared to non-LD counterparts.TFRC,ARC,and URC were significantly higher in females with LD than non-LD females(P=0.01,0.03,and 0.001).Males with LD showed significantly lower TFRC,RRC,and URC counts than the non-LD males(P=0.02,0.01,and 0.001).TFRC can predict LD in males(odds ratio[OR]=1.010,P=0.032)and females(OR=0.993,P=0.012).Fingerprint pattern and ridge counts are sexually dimorphic in subjects with or without LD.TFRC and whorl fingerprint patterns may be vital predictive and screening tools for LD in males and females. 展开更多
关键词 DERMATOGLYPHICS finger ridge count fingerprint patterns learning disability predictive tool sexual dimorphism
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Authentication and distinction of Shenmai injection with HPLC fingerprint analysis assisted by pattern recognition techniques 被引量:5
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作者 Xue-Feng Lu Kai-Shun Bi +1 位作者 Xu Zhao Xiao-Hui Chen 《Journal of Pharmaceutical Analysis》 CAS 2012年第5期327-333,共7页
In this paper, the feasibility and advantages of employing high performance liquid chromatographic (HPLC) fingerprints combined with pattern recognition techniques for quality control of Shenmai injection were inves... In this paper, the feasibility and advantages of employing high performance liquid chromatographic (HPLC) fingerprints combined with pattern recognition techniques for quality control of Shenmai injection were investigated and demonstrated. The Similarity Evaluation System was employed to evaluate the similarities of samples of Shenmai injection, and the HPLC generated chromatographic data were analyzed using hierarchical clustering analysis (HCA) and soft independent modeling of class analogy (SIMCA). Consistent results were obtained to show that the authentic samples and the blended samples were successfully classified by SIMCA, which could be applied to accurate discrimination and quality control of Shenmai injection. Furthermore, samples could also be grouped in accordance with manufacturers. Our results revealed that the developed method has potential perspective for the original discrimination and quality control of Shenmai injection. 展开更多
关键词 Shenmai injection High performance liquidchromatography fingerprint pattern recognition
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Research on Intelligent Identification of PD Patterns Based on the Fingerprint Features 被引量:1
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作者 Qiuping Zheng Ting Chen +4 位作者 Haitao Hu Yingli Wang Dawei Zhao Chuntian Chen Dianchun Zheng 《Applied Mathematics》 2022年第11期896-916,共21页
Five-electrode configurations were designed to simulate the distribution inhomogeneity of electric field intensities in the air-insulating medium, and the characteristic data waveforms of partial discharge generated b... Five-electrode configurations were designed to simulate the distribution inhomogeneity of electric field intensities in the air-insulating medium, and the characteristic data waveforms of partial discharge generated by different electrode configurations under the excitation of power frequency AC voltage were carefully collected in this paper. Furthermore, the feature vectors of the corresponding fingerprint, contained in partial discharge data, were extracted by rigorous mathematical algorithms, and the artificial neural network was employed to realize the pattern recognition of partial discharge caused by the inhomogeneity of electric field intensity with different electrode configurations. The results indicate that the J<sub>4</sub> value in the space of 7 feature quantities is 1905.6, and the recognition rate is 100% when the hidden layer neuron of the network is 19. However, the J<sub>5</sub> value of 9 feature quantities is 1589.9, and the purpose of recognition has been achieved when the number of hidden layer neurons of the network is 6. Increasing the number of hidden layer neurons will only waste computing resources. Of course, PD information collection mode, feature quantity selection, optimal feature space composition, network structure and classification algorithm are the key to realizing PD fault intelligence identification. 展开更多
关键词 PD fingerprint Feature Extraction pattern Recognition Class Separability
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Investigation and Application of Automatic Fingerprint Identification Based on Fuzzy Pattern Recognition 被引量:1
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作者 杨阳 康景利 +1 位作者 郭银景 唐富华 《Journal of Beijing Institute of Technology》 EI CAS 2004年第S1期49-53,共5页
Fingerprint image is a typical non-restraint image that has some uncertainty, which makes it difficult to perform identification using classical approach. Therefore, fuzzy pattern recognition is applied to match indiv... Fingerprint image is a typical non-restraint image that has some uncertainty, which makes it difficult to perform identification using classical approach. Therefore, fuzzy pattern recognition is applied to match individual query by searching the entire template database. The fuzzy maximum subordinate principle is used to solve shift matching. Through experimenting and analyzing, the approximate principle fuzzy method is employed by selecting fuzzy characteristics and determining the similarity function to achieve the further accuracy. Theoretical and experimental results show this approach is effective and reasonable. 展开更多
关键词 fuzzy pattern recognition fingerprint identification maximum subordinate principle approximate principle
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Development and Distinction of <i>Rhizoma rodgersiae</i>with HPLC-DAD Fingerprint Analysis Combined with Chemical Pattern Recognition Techniques
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作者 Yan Wang Yang Jin 《American Journal of Analytical Chemistry》 2017年第11期681-689,共9页
In this paper, the feasibility and advantages of employing high performance liquid chromatographic-photodiode array detection (HPLC-DAD) fingerprint combined with chemical pattern recognition for quality consistency e... In this paper, the feasibility and advantages of employing high performance liquid chromatographic-photodiode array detection (HPLC-DAD) fingerprint combined with chemical pattern recognition for quality consistency evaluation of widely used Rhizoma rodgersiae (RR) were investigated and demonstrated for the first time. The Similarity Evaluation System was employed to evaluate the similarities of 10 batches of RR sample;moreover, hierarchical clustering analysis (HCA) and principal component analysis (PCA) were also successfully applied to discriminate RR samples of different regions and seasons. Our results indicated that the seasonal variation had some influence on the chemical fingerprints of this herbal drug. This approach allowed the discrimination of RR samples from different sources. The current study demonstrated that fingerprint profiling coupled with chemical pattern recognition offered a reliable and efficient way to comprehensively assess the quality consistency of the tested samples. 展开更多
关键词 Chemical pattern Recognition HPLC-DAD fingerprinting Quality CONSISTENCY Evaluation
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基于谱效-毒关系探讨川楝子醋炙减毒增效物质基础
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作者 牛乐 张雨 +2 位作者 范蒙蒙 李红伟 李凯 《中华中医药学刊》 北大核心 2026年第1期72-76,I0008,共6页
目的基于谱效关系和谱毒关系探讨川楝子醋炙减毒增效机理,为其进一步开发利用提供参考。方法采用UPLC双波长测定法,建立川楝子生品及醋炙品指纹图谱,结合主成分分析和偏最小二乘法分析评价川楝子醋炙前后成分变化;以二甲苯致耳肿胀为炎... 目的基于谱效关系和谱毒关系探讨川楝子醋炙减毒增效机理,为其进一步开发利用提供参考。方法采用UPLC双波长测定法,建立川楝子生品及醋炙品指纹图谱,结合主成分分析和偏最小二乘法分析评价川楝子醋炙前后成分变化;以二甲苯致耳肿胀为炎症模型,以炎症抑制率为指标考察川楝子醋炙前后抗炎活性;以血清中总胆汁酸(TBA)、谷草转氨酶(AST)、谷丙转氨酶(ALT)、碱性磷酸酶(ALP)的含量为指标考察川楝子醋炙前后肝毒性作用;采用灰色关联度法考察分析川楝子醋炙前后指纹图谱与抗炎作用和肝毒性的相关性。结果指纹图谱研究显示,生品与醋炙品在210、254 nm波长下分别共匹配16个和13个共有峰;采用主成分分析可将生川楝子与醋川楝子明显区分,采用正交偏最小二乘-判别分析筛选出醋炙前后共13个差异性成分。谱效关系结果显示川楝素、阿魏酸、芦丁、异槲皮苷是抗炎作用关联度较大的化学成分,谱毒关系结果显示川楝素是与肝毒性关联度最大的化学成分。结论川楝子醋炙后可有效降低肝毒性,并增强抗炎活性,川楝子醋炙减毒增效与川楝素、阿魏酸、芦丁、异槲皮苷的成分变化有关,这为川楝子醋炙品的临床应用提供依据。 展开更多
关键词 川楝子 醋炙 指纹图谱 化学模式识别 谱效-毒关系 抗炎作用 肝毒性
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银翘汤HPLC指纹图谱研究、化学模式识别及含量测定
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作者 隋欣蕙 靳彤 +3 位作者 邵丰德 门操 王栋 赵春杰 《沈阳药科大学学报》 2026年第2期172-183,198,共13页
目的基于高效液相色谱法建立10批银翘汤指纹图谱,结合化学识别评价其质量,并同时测定银翘汤中没食子酸甲酯、绿原酸、葛根素、升麻素、甘草酸铵5种成分的含量。方法分析采用Spherisorb ODS-2 C_(18)色谱柱(250 mm×4.0 mm,5μm);流... 目的基于高效液相色谱法建立10批银翘汤指纹图谱,结合化学识别评价其质量,并同时测定银翘汤中没食子酸甲酯、绿原酸、葛根素、升麻素、甘草酸铵5种成分的含量。方法分析采用Spherisorb ODS-2 C_(18)色谱柱(250 mm×4.0 mm,5μm);流动相为0.1%磷酸水(A)-乙腈(B)溶液,梯度洗脱;柱温为35℃;检测波长为254 nm;流速为1.0 mL·min^(-1)。使用“中药色谱指纹图谱相似度评价系统”、SPSS 19.0、SIMCA 13.0等软件建立指纹图谱、评价相似度并进行多元统计分析;通过外标法计算没食子酸甲酯、绿原酸、葛根素、升麻素、甘草酸铵5种成分的含量。结果在254 nm下,标定出26个共有峰,指认出5个色谱峰,相似度范围为0.997~0.999;化学模式识别结果表明,10批银翘汤可分为2类,质量最高的批次为S9,并筛选出9个差异性标志物。没食子酸甲酯、绿原酸、葛根素、升麻素、甘草酸铵分别在各自范围内呈良好线性关系(r均大于0.9998),回收率范围为95.6%~100.8%,RSD为0.8%~1.7%,10批银翘汤中5种成分的含量分别为13.805~20.032 mg·L^(-1)、108.345~114.386 mg·L^(-1)、16.929~19.389 mg·L^(-1)、9.646~13.394 mg·L^(-1)、29.208~31.654 mg·L^(-1)。结论建立的HPLC银翘汤指纹图谱及多成分含量测定分析方法稳定、简单、可靠,同时结合化学模式识别分析,可为银翘汤的质量控制提供参考。 展开更多
关键词 银翘汤 中药指纹图谱 含量测定 化学模式识别
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基于高效液相色谱指纹图谱结合多成分含量测定的通脉降糖胶囊质量控制的研究
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作者 李叶 杨长花 +9 位作者 罗晨曦 杨青 王苗 赵扬 谭未未 周佳琳 彭修娟 黄壮壮 刘峰 陈衍斌 《西北药学杂志》 2026年第1期35-41,共7页
目的建立通脉降糖胶囊的高效液相色谱(high-performance liquid chromatography,HPLC)指纹图谱,同步建立其6种特征成分的含量测定方法,以期完善该制剂的质量控制体系。方法采用Diamonsil Plus C_(18)色谱柱(250 mm×4.6 mm,5μm);... 目的建立通脉降糖胶囊的高效液相色谱(high-performance liquid chromatography,HPLC)指纹图谱,同步建立其6种特征成分的含量测定方法,以期完善该制剂的质量控制体系。方法采用Diamonsil Plus C_(18)色谱柱(250 mm×4.6 mm,5μm);以乙腈-体积分数0.1%磷酸水溶液为流动相,指纹图谱采用梯度洗脱程序1,含量测定采用梯度洗脱程序2;检测波长为250 nm;流速为1.0 mL·min^(-1);柱温为35℃;进样量为10μL。借助中药色谱指纹图谱相似度评价系统(2012版),构建11批通脉降糖胶囊的HPLC指纹图谱并进行相似度评价。结果指纹图谱共标识24个共有峰,其中10种成分得到指认;方法学考察结果显示,该方法精密度、重复性、稳定性均良好,11批通脉降糖胶囊指纹图谱的相似度均>0.99,化学成分一致性良好。6种成分含量测定结果显示,标准曲线线性关系良好(R^(2)≥0.999),平均加样回收率为91.93%~106.13%,回收率相对标准偏差(relative standard deviation,RSD)≤2.65%。结论所建立的HPLC指纹图谱和多成分含量测定方法准确、灵敏、重复性良好,为通脉降糖胶囊的质量控制提供了科学依据。 展开更多
关键词 通脉降糖胶囊 多成分含量测定 高效液相色谱 指纹图谱 质量控制
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基于“指纹图谱-模式识别-血清移行成分”整合策略筛选清消五味汤质量差异标志物
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作者 施凯桃 李君 +1 位作者 张谦 马宇衡 《山东科学》 2026年第1期11-20,共10页
通过清消五味汤高效液相指纹图谱,并结合化学模式识别方法,体内外成分鉴定方法,筛选差异成分,为其质量一致性研究及其复方制剂开发提供参考。建立18个批次的清消五味汤指纹图谱并进行相似度评价;采用生物信息学方法对其质量标志物进行... 通过清消五味汤高效液相指纹图谱,并结合化学模式识别方法,体内外成分鉴定方法,筛选差异成分,为其质量一致性研究及其复方制剂开发提供参考。建立18个批次的清消五味汤指纹图谱并进行相似度评价;采用生物信息学方法对其质量标志物进行筛选分析;采用高效液相色谱-四极杆/静电场轨道阱高分辨质谱(HPLC-Q-Exactive-MS)法对清消五味汤的体外化学成分和体内血清移行成分进行鉴定,并基于“指纹图谱-模式识别-血清移行成分”整合策略筛选清消五味汤质量差异标志物。在清消五味汤指纹图谱共确定了28个峰,并筛选出大黄酚等8个质量差异标志物。鉴定出85个清消五味汤体外化学成分,55个血清移行成分,利用韦恩图将指纹图谱筛选的成分与体内和体外鉴定的成分取交集,得到核心质量差异标志物大黄酚。该研究建立了一种操作简便、重现性良好,分析方法能够有效评价不同批次清消五味汤的质量稳定性与批次间一致性,为该方剂的工艺优化、质量标准制定及后续开发研究提供可靠的数据支持。 展开更多
关键词 清消五味汤 指纹图谱 模式识别 血清移行成分 质量标志物
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土家族药物烂泥巴树HPLC指纹图谱建立及化学模式识别研究
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作者 张万涛 王常清 +2 位作者 杨江帆 夏永芳 覃鸿恩 《安徽医药》 2026年第3期503-510,共8页
目的建立土家族药物烂泥巴树高效液相色谱法(HPLC)指纹图谱,并进行化学模式识别分析评价烂泥巴树药材质量。方法于2023年4—10月建立烂泥巴树的HPLC指纹图谱分析方法(色谱柱:Kromasil 100-5 C_(18);流动相:乙腈-0.2%磷酸水),并应用于9... 目的建立土家族药物烂泥巴树高效液相色谱法(HPLC)指纹图谱,并进行化学模式识别分析评价烂泥巴树药材质量。方法于2023年4—10月建立烂泥巴树的HPLC指纹图谱分析方法(色谱柱:Kromasil 100-5 C_(18);流动相:乙腈-0.2%磷酸水),并应用于9批不同产地样品的分析。通过相似度评价与聚类分析、主成分分析(PCA)、正交偏最小二乘判别分析(OPLS-DA)等多种化学模式识别技术的联用,实现对样品的综合分析与鉴别。结果建立了土家族药物烂泥巴树HPLC指纹图谱,共提取17个共有峰,并指认出3号峰为紫丁香苷,4号峰为绿原酸,9批烂泥巴树指纹图谱与对照指纹图谱的相似度均大于0.9,聚类分析将药材分为2类,PCA、OPLS-DA结果与聚类分析一致,并筛选出11个差异标志物。结论建立的土家族药物烂泥巴树HPLC指纹图谱相似度好;结合化学模式识别,可以为不同产地烂泥巴树质量控制提供参考。 展开更多
关键词 山茱萸科 医学 中国传统 烂泥巴树 土家族 紫丁香苷 绿原酸 指纹图谱 化学模式识别
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基于双波长指纹图谱结合化学模式识别的平纳蜜膏质量标准研究
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作者 张明惠 杨青青 +2 位作者 尹梦晴 张晓莉 马璇 《药学前沿》 2026年第2期211-218,共8页
目的建立10批平纳蜜膏双波长指纹图谱,并结合化学模式识别方法,为其质量控制及标准制定提供依据。方法采用HPLC法,色谱柱为Shim Nex CS C_(18)柱(250 mm×4.6 mm,5μm),流动相为乙腈-0.4%磷酸水溶液,梯度洗脱,柱温为30℃,流速为1.0 ... 目的建立10批平纳蜜膏双波长指纹图谱,并结合化学模式识别方法,为其质量控制及标准制定提供依据。方法采用HPLC法,色谱柱为Shim Nex CS C_(18)柱(250 mm×4.6 mm,5μm),流动相为乙腈-0.4%磷酸水溶液,梯度洗脱,柱温为30℃,流速为1.0 mL/min,检测波长为330 nm和245 nm,进样量为10μL。采用中药色谱指纹图谱相似度评价系统(2012版)对10批平纳蜜膏的HPLC色谱图进行分析,建立双波长指纹图谱。然后针对330 nm波长下的指纹图谱,进一步进行了聚类分析、主成分分析以及正交偏最小二乘法-判别分析。结果建立10批平纳蜜膏的HPLC双波长(330 nm与245 nm)指纹图谱,分别在两波长下标定13个与7个共有峰。通过与对照品对比,指认出咖啡酸、蒙花苷、木犀草素、芹菜素、一枝蒿酮酸共5种成分,所有样品相似度均大于0.9。化学模式识别分析结果表明,10批样品可划分为3类,并筛选出峰2(咖啡酸)、峰10、峰1、峰3、峰6(蒙花苷)共5个差异性成分。结论本研究建立的双波长指纹图谱以及化学模式识别方法准确可靠,可为平纳蜜膏的质量标准研究提供重要的数据支持。 展开更多
关键词 平纳蜜膏 双波长 指纹图谱 高效液相色谱 化学模式识别 质量标准 质量控制
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Fingerprint Recognition with Artificial Neural Networks: Application to E-Learning 被引量:2
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作者 Stephane Kouamo Claude Tangha 《Journal of Intelligent Learning Systems and Applications》 2016年第2期39-49,共11页
Fingerprint recognition is a mature biometric technique for identification or authentication application. In this work, we describe a method based on the use of neural network to authenticate people who want to accede... Fingerprint recognition is a mature biometric technique for identification or authentication application. In this work, we describe a method based on the use of neural network to authenticate people who want to accede to an automated fingerprint system for E-learning. The idea is to apply back propagation algorithm on a multilayer perceptron during the training stage. One of the advantages of this technique is the use of a hidden layer which allows the network to make comparison by calculating probabilities on template which are invariant to translation and rotation. Results come both from the NIST special database 4 and a local database, and show that a proposed method gives good results in some cases. 展开更多
关键词 Neural Networks pattern Recognition fingerprint BACK-PROPAGATION E-LEARNING
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Bohai crude oil identification by gas chromatogram fingerprinting quantitative analysis coupled with cluster analysis 被引量:4
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作者 SUN Peiyan BAO Mutai +5 位作者 GAO Zhenhui LI Mei ZHAO Yuhui WANG Xinping ZHOU Qing WANG Xiulin 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2006年第5期55-62,共8页
By gas chromatogram, six crude oils fingerprinting distributed in four oilfields and four oil platforms were analyzed and the corre- sponding normal paraffin hydrocarbon ( including pristane and phytane) concentrati... By gas chromatogram, six crude oils fingerprinting distributed in four oilfields and four oil platforms were analyzed and the corre- sponding normal paraffin hydrocarbon ( including pristane and phytane) concentration was obtained by the internal standard methed. The normal paraffin hydrocarbon distribution patterns of six crude oils were built and compared. The cluster analysis on the normal paraffin hydrocarbon concentration was conducted for classification and some ratios of oils were used for oils comparison. The results indicated: there was a clear difference within different crude oils in different oil fields and a small difference between the crude oils in the same oil platform. The normal paraffin hydrocarbon distribution pattern and ratios, as well as the cluster analysis on the nomad paraffin hydrocarbon concentration can have a better differentiation result for the crude oils with small difference than the original gas chromatogram. 展开更多
关键词 oil fingerprinting identification gas chromatogram normal paraffin hydrocarbons distribution pattern RATIO cluster analysis
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K-Means Graph Database Clustering and Matching for Fingerprint Recognition
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作者 Vaishali Pawar Mukesh Zaveri 《Intelligent Information Management》 2015年第4期242-251,共10页
The graph can contain huge amount of data. It is heavily used for pattern recognition and matching tasks like symbol recognition, information retrieval, data mining etc. In all these applications, the objects or under... The graph can contain huge amount of data. It is heavily used for pattern recognition and matching tasks like symbol recognition, information retrieval, data mining etc. In all these applications, the objects or underlying data are represented in the form of graph and graph based matching is performed. The conventional algorithms of graph matching have higher complexity. This is because the most of the applications have large number of sub graphs and the matching of these sub graphs becomes computationally expensive. In this paper, we propose a graph based novel algorithm for fingerprint recognition. In our work we perform graph based clustering which reduces the computational complexity heavily. In our algorithm, we exploit structural features of the fingerprint for K-means clustering of the database. The proposed algorithm is evaluated using realtime fingerprint database and the simulation results show that our algorithm outperforms the existing algorithm for the same task. 展开更多
关键词 pattern Recognition fingerprint MATCHING GRAPH MATCHING CLUSTERING
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基于指纹图谱结合化学模式识别以及网络药理学筛选经典名方旋覆代赭汤的质量标志物 被引量:1
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作者 汪怡 郭曼曼 +3 位作者 徐倩菲 徐韫妍 张泽鹏 刘菊 《中南药学》 2025年第2期385-391,共7页
目的通过指纹图谱结合化学模式识别以及网络药理学筛选旋覆代赭汤的质量标志物。方法用不同方法制备15批旋覆代赭汤供试品,建立UPLC指纹图谱并进行共有峰指认和相似度评价。运用聚类分析及正交偏最小二乘判别分析等化学模式识别方法对... 目的通过指纹图谱结合化学模式识别以及网络药理学筛选旋覆代赭汤的质量标志物。方法用不同方法制备15批旋覆代赭汤供试品,建立UPLC指纹图谱并进行共有峰指认和相似度评价。运用聚类分析及正交偏最小二乘判别分析等化学模式识别方法对指纹图谱进行研究,寻找造成差异的标志性成分,再运用网络药理学预测标志性成分的作用靶点和通路,构建“成分-靶点-通路”网络图,并进行细胞实验验证,从而筛选出旋覆代赭汤的质量标志物。结果15批旋覆代赭汤中共有23个共有峰,指认出其中16个成分并对其进行归属,化学模式识别分析寻找出4个差异标志性成分。通过网络药理学筛选出这4个成分的20个关键靶点和20条关键信号通路,通过细胞实验,发现旋覆代赭汤可显著抑制脂多糖诱导的巨噬细胞RAW264.7炎症模型中STAT3和JAK2磷酸化,结果表明绿原酸、1,5-二咖啡酰奎宁酸、1-O-乙酰旋覆花内酯、人参皂苷Rb1这4个成分可作为旋覆代赭汤潜在的质量标志物。结论该方法筛选出4个可作为旋覆代赭汤潜在质量标志物的化学成分,为旋覆代赭汤质量标准的建立提供了基础和借鉴,同时也为旋覆代赭汤相关制剂的开发提供参考。 展开更多
关键词 旋覆代赭汤 指纹图谱 化学模式识别 网络药理学 质量标志物
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Reduction of False Rejection in an Authentication System by Fingerprint with Deep Neural Networks
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作者 Stéphane Kouamo Claude Tangha Olaf Kouamo 《Journal of Software Engineering and Applications》 2020年第1期1-13,共13页
Faultless authentication of individuals by fingerprints results in high false rejections rate for rigorously built systems. Indeed, the authors prefer that the system erroneously reject a pattern when it does not meet... Faultless authentication of individuals by fingerprints results in high false rejections rate for rigorously built systems. Indeed, the authors prefer that the system erroneously reject a pattern when it does not meet a number of predetermined correspondence criteria. In this work, after discussing existing techniques, we propose a new algorithm to reduce the false rejection rate during the authentication-using fingerprint. This algorithm extracts the minutiae of the fingerprint with their relative orientations and classifies them according to the different classes already established;then, make the correspondence between two templates by simple probabilities calculations from a deep neural network. The merging of these operations provides very promising results both on the NIST4 international data reference and on the SOCFing database. 展开更多
关键词 AUTHENTICATION fingerprint False REJECTION NEURAL Networks pattern RECOGNITION Deep Learning
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基于HPLC指纹图谱、模式识别与网络药理学的当归-川芎药对质量标志物研究
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作者 顾志荣 赵丽婷 +2 位作者 张诗烨 卢天亦 葛斌 《中国野生植物资源》 2025年第12期22-32,共11页
目的:综合运用HPLC指纹图谱、模式识别与网络药理学技术分析当归-川芎药对的质量标志物(Qmarker)。方法:建立当归-川芎药对的高效液相色谱(HPLC)指纹图谱,对指纹图谱进行主成分分析(PCA)、正交偏最小二乘-判别分析(OPLS-DA)等模式识别分... 目的:综合运用HPLC指纹图谱、模式识别与网络药理学技术分析当归-川芎药对的质量标志物(Qmarker)。方法:建立当归-川芎药对的高效液相色谱(HPLC)指纹图谱,对指纹图谱进行主成分分析(PCA)、正交偏最小二乘-判别分析(OPLS-DA)等模式识别分析,通过网络药理学方法建立“成分-靶点-效应”网络,综合分析当归-川芎药对的Q-marker。结果:建立的当归-川芎药对HPLC指纹图谱共确定了23个共有峰,指认了其中9个共有峰,15批样品指纹图谱的相似度在0.976~0.998之间。PCA分析表明藁本内酯、阿魏酸、3-丁基苯酞、绿原酸可能是潜在的Q-marker。OPLS-DA分析表明藁本内酯、阿魏酸、绿原酸、3-丁基苯酞、二丁基苯酞可能是潜在的Qmarker。网络药理学分析表明,3-丁基苯酞、阿魏酸、正丁烯基苯酞、绿原酸、杨梅酮、藁本内酯、4-羟基-3-丁基苯酞7个成分通过ESR1、PPARG、RXRA、EGFR、JUN等11个关键靶点在生物活性中发挥了关键作用,可能是潜在Qmarker。综合分析表明,阿魏酸、藁本内酯、3-丁基苯酞3个成分适宜作为当归-川芎药对的Q-marker。结论:综合利用HPLC指纹图谱、模式识别与网络药理学方法分析了当归-川芎药对的Q-marker,为其全面质量控制提供依据。 展开更多
关键词 当归-川芎药对 指纹图谱 模式识别 网络药理学 质量标志物
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基于HPLC指纹图谱及化学模式识别的山慈菇(冰球子)及其潜在代用品的鉴定研究
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作者 张超 高一军 +4 位作者 孙启慧 郭衍珩 刘延娟 容蓉 赵丹彤 《中草药》 北大核心 2025年第12期4419-4426,共8页
目的建立山慈菇Pleiones Pseudobulbus(冰球子)及其潜在代用品的HPLC指纹图谱,并结合化学模式识别寻找山慈菇(冰球子)及其潜在代用品的差异性成分,筛选山慈菇(冰球子)最佳代用品。方法使用乙腈-0.1%磷酸水溶液作流动相进行梯度洗脱,Agil... 目的建立山慈菇Pleiones Pseudobulbus(冰球子)及其潜在代用品的HPLC指纹图谱,并结合化学模式识别寻找山慈菇(冰球子)及其潜在代用品的差异性成分,筛选山慈菇(冰球子)最佳代用品。方法使用乙腈-0.1%磷酸水溶液作流动相进行梯度洗脱,Agilent ZORBAX SB-C_(18)色谱柱(250 mm×4.6 mm,5μm),检测波长224 nm,进样量25μL,柱温为30℃,体积流量为0.8 mL/min,建立40批样品HPLC指纹图谱,结合相似度评价、特征图谱、聚类热图分析、主成分分析(principalcomponent analysis,PCA)、正交偏最小二乘法判别分析(orthogonal partial least squares discriminant analysis,OPLS-DA)对特征成分进行数据分析。结果40批样品共有5个共有峰,经对照品比对指认出了5个成分,分别为天麻素、对羟基苯甲醇、dactylorhin A、militarine、山药素III。聚类热图和PCA分析结果可将山慈菇(冰球子)及其潜在代用品进行区分,并结合相似度评价,初步判断带唇兰Tainia dunnii为山慈菇(冰球子)最佳代用品。不同基原样品的HPLC典型特征图谱结合OPLS-DA分析与PCA分析,筛选出山慈菇(冰球子)正品基原与其潜在代用品的主要差异性指标成分为loroglossin、dactylorhin A和militarine。结论建立的指纹图谱结合化学模式识别方法可用于山慈菇(冰球子)及其潜在代用品的区分及山慈菇(冰球子)最佳代用品的筛选。 展开更多
关键词 山慈菇(冰球子) 指纹图谱 相似度 化学模式识别 代用品 天麻素 对羟基苯甲醇 dactylorhin A militarine 山药素Ⅲ
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基于UPLC指纹图谱及含量测定结合化学模式识别法评价不同产地北沙参药材质量 被引量:1
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作者 张欣 廖玉瑶 +3 位作者 韦怀福 张勇纯 务勇圣 郑顺亮 《亚太传统医药》 2025年第11期34-41,共8页
目的:建立北沙参药材UPLC指纹图谱及腺苷含量测定方法,研究不同产地北沙参药材的水分、浸出物和含量,并结合化学模式识别分析比较不同产地北沙参药材的质量差异,为完善北沙参药材质量标准提供参考依据。方法:采用Agilent ZORBAX Eclipse... 目的:建立北沙参药材UPLC指纹图谱及腺苷含量测定方法,研究不同产地北沙参药材的水分、浸出物和含量,并结合化学模式识别分析比较不同产地北沙参药材的质量差异,为完善北沙参药材质量标准提供参考依据。方法:采用Agilent ZORBAX Eclipse Plus C_(18)(50 mm×2.1 mm,1.8μm)色谱柱,乙腈-0.1%甲酸溶液为流动相,进行梯度洗脱,流速0.3 mL/min,柱温30℃,检测波长290 nm,进样量1μL,建立21批不同产地北沙参药材指纹图谱,进行相似度评价和化学模式识别;同时建立腺苷含量测定方法,并对不同产地北沙参药材进行水分和浸出物测定。结果:北沙参UPLC指纹图谱标定22个共有峰并指认其中3个色谱峰,通过化学模式识别方法,将21批药材按照产地分为3类,并筛选出13个质量差异性成分。21批次北沙参药材腺苷含量为0.010%~0.051%,水分含量为7.7%~10.1%,水溶性浸出物含量为43.1%~68.6%。结论:该研究建立的北沙参药材UPLC指纹图谱及含量测定方法稳定、重复性好,化学模式识别法可较好地筛选出差异性成分,可为北沙参药材质量评价和控制提供参考依据。 展开更多
关键词 北沙参 UPLC指纹图谱 含量测定 化学模式识别 质量评价
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基于HPLC指纹图谱相似度分析和化学模式识别的西藏药用麻黄品种研究
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作者 张勇仓 白玛卓玛 +2 位作者 强巴 旦增尼玛 刘兰 《高原科学研究》 2025年第2期72-81,共10页
目的:基于HPLC图谱相似度分析和化学模式识别对西藏药用麻黄品种进行研究。方法:HPLC采用Phenomenex luna-C18色谱柱(4.6 mm×250 mm,5μm);流动相A:磷酸(0.05%)-三乙胺(0.05%)水溶液,流动相B:乙腈,梯度洗脱;柱温30℃;流速1.0 mL/m... 目的:基于HPLC图谱相似度分析和化学模式识别对西藏药用麻黄品种进行研究。方法:HPLC采用Phenomenex luna-C18色谱柱(4.6 mm×250 mm,5μm);流动相A:磷酸(0.05%)-三乙胺(0.05%)水溶液,流动相B:乙腈,梯度洗脱;柱温30℃;流速1.0 mL/min;检测波长200 nm。选取各批次麻黄药材色谱图中的主要共有峰作为变量,运用SPSS 21.0软件进行聚类分析和主成分分析对药材进行化学模式识别。结果:12批西藏药用麻黄HPLC指纹图谱中有8个共有峰,相似度在0.546~0.922之间;12批样品聚类分为4大类,与主成分分析结果基本一致,表现出明显的按生境聚类的特征。结论:该方法稳定可靠,可为西藏药用麻黄品种研究和质量控制提供参考。 展开更多
关键词 西藏药用麻黄 HPLC指纹图谱 化学模式识别 品种研究
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