The application of appropriate cell origin for utilizing inregenerative medicine is the major issue. Various kinds of stem cells have been used for the tissue engineering and regenerative medicine. Such as, several st...The application of appropriate cell origin for utilizing inregenerative medicine is the major issue. Various kinds of stem cells have been used for the tissue engineering and regenerative medicine. Such as, several stromal cells have been employed as treat option for regenerative medicine. For example, human bone marrow-derived stromal cells and adipose-derived stromal cells(ADSCs) are used in cell-based therapy. Data relating to the stem cell therapy and processes associated with ADSC has developed remarkably in the past 10 years. As medical options, both the stromal vascular and ADSC suggests good opportunity as marvelous cell-based therapeutics. The some biological features are the main factors that impact the regenerative activity of ADSCs, including the modulation of the cellular immune system properties and secretion of bioactive proteins such as cytokines, chemokines and growth factors, as well as their intrinsic anti-ulcer and anti-inflammatory potential. A variety of diseases have been treated by ADSCs, and it is not surprising that there has been great interest in the possibility that ADSCs might be used as therapeutic strategy to improve a wider range of diseases. This is especially important when it is remembered that routine therapeutic methods are not completely effective in treat of diseases. Here, it was discuss about applications of ADSC to colitis, liver failure, diabetes mellitus, multiple sclerosis, orthopaedic disorders, hair loss, fertility problems, and salivary gland damage.展开更多
Background and Objectives:This study compared the accuracy of current energy formulas in predicting resting energy expenditure(REE)in overweight and obese women with fertility problems.Methods and Study Design:This st...Background and Objectives:This study compared the accuracy of current energy formulas in predicting resting energy expenditure(REE)in overweight and obese women with fertility problems.Methods and Study Design:This study evaluated REE prediction formulas in 82 overweight/obese women(18-49 years)with fertility problems.REE is accurately measured using indirect calorimetry,which is considered the gold standard for evaluating energy.Anthropometric data,including height,weight,and waist circumference.Body composition analysis was performed using bioelectrical impedance analysis to determine fat-free mass and other related indicators.Statistical analyses included Spearman correlation coefficients to assess the relationship between REE and various predictors.The accuracy and reliability of the existing prediction equations were evaluated by comparing their predicted values with resting energy expenditure values measured by Indirect Calorimetry using Bland-Altman analysis.Results:Among the prediction equations assessed,Mifflin's equation demonstrated superior performance in estimating REE in overweight/obese women experiencing fertility problems,exhibiting the least bias(-9.7 kcal/day)and a low standard deviation(240 kcal/day).Variables such as body weight,lean body weight,and central obesity indicators like waist circumference and waist-height ratio emerged as significant predictors of REE,with their impacts being age-dependent.The Mifflin-St.Jeor Equation,which integrates weight,height,and age variables,offers a reasonably accurate estimation of energy needs for this specific demographic.Conclusions:The Mifflin-St.Jeor Equation is an accurate tool for predicting REE in overweight and obese women with fertility problems,offering important insights for nutritional assessment and intervention strategies in fertility management.展开更多
文摘The application of appropriate cell origin for utilizing inregenerative medicine is the major issue. Various kinds of stem cells have been used for the tissue engineering and regenerative medicine. Such as, several stromal cells have been employed as treat option for regenerative medicine. For example, human bone marrow-derived stromal cells and adipose-derived stromal cells(ADSCs) are used in cell-based therapy. Data relating to the stem cell therapy and processes associated with ADSC has developed remarkably in the past 10 years. As medical options, both the stromal vascular and ADSC suggests good opportunity as marvelous cell-based therapeutics. The some biological features are the main factors that impact the regenerative activity of ADSCs, including the modulation of the cellular immune system properties and secretion of bioactive proteins such as cytokines, chemokines and growth factors, as well as their intrinsic anti-ulcer and anti-inflammatory potential. A variety of diseases have been treated by ADSCs, and it is not surprising that there has been great interest in the possibility that ADSCs might be used as therapeutic strategy to improve a wider range of diseases. This is especially important when it is remembered that routine therapeutic methods are not completely effective in treat of diseases. Here, it was discuss about applications of ADSC to colitis, liver failure, diabetes mellitus, multiple sclerosis, orthopaedic disorders, hair loss, fertility problems, and salivary gland damage.
基金supported by the Scientific Research Project Plan of Traditional Chinese Medicine in Hebei Province(No.2025033)the National Nutrition Research Foundation of Chinese Nutrition Society(CNS-NNSRG2022-231)the Natural Science Foundation of Hebei Province(No.H2023206219)。
文摘Background and Objectives:This study compared the accuracy of current energy formulas in predicting resting energy expenditure(REE)in overweight and obese women with fertility problems.Methods and Study Design:This study evaluated REE prediction formulas in 82 overweight/obese women(18-49 years)with fertility problems.REE is accurately measured using indirect calorimetry,which is considered the gold standard for evaluating energy.Anthropometric data,including height,weight,and waist circumference.Body composition analysis was performed using bioelectrical impedance analysis to determine fat-free mass and other related indicators.Statistical analyses included Spearman correlation coefficients to assess the relationship between REE and various predictors.The accuracy and reliability of the existing prediction equations were evaluated by comparing their predicted values with resting energy expenditure values measured by Indirect Calorimetry using Bland-Altman analysis.Results:Among the prediction equations assessed,Mifflin's equation demonstrated superior performance in estimating REE in overweight/obese women experiencing fertility problems,exhibiting the least bias(-9.7 kcal/day)and a low standard deviation(240 kcal/day).Variables such as body weight,lean body weight,and central obesity indicators like waist circumference and waist-height ratio emerged as significant predictors of REE,with their impacts being age-dependent.The Mifflin-St.Jeor Equation,which integrates weight,height,and age variables,offers a reasonably accurate estimation of energy needs for this specific demographic.Conclusions:The Mifflin-St.Jeor Equation is an accurate tool for predicting REE in overweight and obese women with fertility problems,offering important insights for nutritional assessment and intervention strategies in fertility management.
