Background Clinical brain-computer interface(BCI)for mental disorders is an emerging interdisciplinary research field,posing new ethical concerns and challenges,yet lacking practical ethical governance guidelines for ...Background Clinical brain-computer interface(BCI)for mental disorders is an emerging interdisciplinary research field,posing new ethical concerns and challenges,yet lacking practical ethical governance guidelines for stakeholders and the entire community.Aims This study aims to establish a multidisciplinary consensus of principles for ethical governance of clinical BCI research for mental disorders and offer practical ethical guidance to stakeholders involved.Methods A systematic literature review,symposium and roundtable discussions,and a pre-Delphi(round 0)survey were conducted to form the questionnaire for the three-round modified Delphi study.Two rounds of surveys,followed by a third round of independent interviews of 25 experts from BCI-related research domains,were involved.We conducted quantitative analysis of responses and agreements among experts to reveal the consensus and differences regarding the ethical governance of mental BCI research from a multidisciplinary perspective.Results The Delphi panel emphasised important concerns of ethical review practices and ethical principles within the BCI context,identified qualified and highly influential institutions and personnel in conducting and advancing clinical BCI research,and recognised prioritised aspects in the risk-benefit evaluation.Experts expressed diverse opinions on specific ethical concerns,including concerns about invasive technology,its impact on humanity and potential social consequences.Agreement was reached that the practices of ethical governance of clinical BCI for mental disorders should focus on patient voluntariness,autonomy,long-term effects and related assessments of BCI interventions,as well as privacy protection,transparent reporting and ensuring that the research is conducted in qualified institutions with strong data security.Conclusions Ethical governance of clinical research on BCI for mental disorders should include interdisciplinary experts to balance various needs and incorporate the expertise of different stakeholders to avoid serious ethical issues.It requires scientifically grounded approaches,continuous monitoring and interdisciplinary collaboration to ensure evidence-based policies,comprehensive risk assessments and transparency,thereby promoting responsible innovations and protecting patient rights and well-being.展开更多
Values of individuals and organizations involved in decision-making processes form the basis for prioritizing outcomes in water governance.The novelty of this study lies in applying values to a specific decision-makin...Values of individuals and organizations involved in decision-making processes form the basis for prioritizing outcomes in water governance.The novelty of this study lies in applying values to a specific decision-making context.It aims to assess the prioritized water governance outcomes and the underlying value systems shaping the actions of the primary water utility responsible for water governance in Delhi,the Delhi Jal Board(DJB).The paper will critically examine the policies and acts of the DJB that drive water governance in Delhi at present,utilizing a values-based framework in conjunction with secondary literature and expert interviews,to draw a picture of the values reflected.The study does not substantiate the notion of economic values dominating the water-related deci-sions;rather,recent policy guidelines indicate prioritization of equitable and fair distribution of water.Findings of this paper show that making the values explicit is largely disregarded in formulating water acts and policies,and values are never elucidated in the public domain,doing which can encourage water policies and practices that are socially,economically,and ecologically viable in the long run.It is expected that this paper will generate a discussion on water values being an integral part of water governance discourses.展开更多
Background:With the rapid development of modern emerging technologies,the ethical dilemmas and social controversies triggered by scientific and technological activities have become increasingly prominent.How to guide ...Background:With the rapid development of modern emerging technologies,the ethical dilemmas and social controversies triggered by scientific and technological activities have become increasingly prominent.How to guide technology for good and prevent and control technological risks has become an important issue of global concern.Research on science and technology ethics is dedicated to integrating ethical theories into governance practices and constructing ethical models that adapt to the development of the times.Methods:This article systematically reviews the six core approaches of scientific and technological ethics thought,including technological autonomy and political philosophy criticism,responsibility ethics and intergenerational obligations,technological intermediation and the integration of life and the world,ethical principles and normative frameworks,participatory governance and ethical practice innovation,as well as domain-specific ethical norms,thereby constructing an ethical analysis framework applicable to medical technology risks.And cross-analysis was conducted by taking medical events such as gene editing and xenotransplantation as examples.Results:Research shows that a single ethical approach has limitations in addressing complex medical ethical challenges,while the six approaches are complementary and synergistic.By criticizing technological autonomy,establishing a responsibility ethics orientation,setting the bottom line of ethical principles,promoting participatory governance,formulating domain norms,and continuously reflecting on the intermediary nature of technology,a multi-level and dynamically adaptive governance system for scientific and technological ethics can be constructed.Conclusion:The key to addressing contemporary medical ethics challenges lies in the comprehensive application of science and technology ethics theories and the integration of ethical considerations throughout the entire process of scientific and technological research and development.In the future,a governance framework that adapts to the development of new technologies should be established to promote cross-cultural and cross-disciplinary ethical dialogue and public participation,ensuring that scientific and technological innovation always serves the dignity of human life and overall well-being.展开更多
Brain-computer interface(BCI)technology is rapidly advancing in medical research and application.As an emerging biomedical engineering technology,it has garnered significant attention in the clinical research of brain...Brain-computer interface(BCI)technology is rapidly advancing in medical research and application.As an emerging biomedical engineering technology,it has garnered significant attention in the clinical research of brain disease diagnosis and treatment,neurological rehabilitation,and mental health.However,BCI also raises several challenges and ethical concerns in clinical research.In this article,the authors investigate and discuss three aspects of BCI in medicine and healthcare:the state of international ethical governance,multidimensional ethical challenges pertaining to BCI in clinical research,and suggestive concerns for ethical review.Despite the great potential of frontier BCI research and development in the field of medical care,the ethical challenges induced by itself and the complexities of clinical research and brain function have put forward new special fields for ethics in BCI.To ensure"responsible innovation"in BCI research in healthcare and medicine,the creation of an ethical global governance framework and system,along with special guidelines for cutting-edge BCI research in medicine,is suggested.展开更多
The 23rd meeting of the Central Committee for Comprehensively Deepening Reform, presided over by General Secretary Xi Jinping, adopted the Guiding Opinions on Strengthening the Governance of Science and Technology Eth...The 23rd meeting of the Central Committee for Comprehensively Deepening Reform, presided over by General Secretary Xi Jinping, adopted the Guiding Opinions on Strengthening the Governance of Science and Technology Ethics on 17 December 2021. On 20March 2022, the General Office of the CPC Central Committee and the General Office of the State Council issued the Opinions on Strengthening the Governance of Science and Technology Ethics.展开更多
Artificial intelligence(AI) has rapidly transformed from a promising computational tool to a central force in global healthcare, exercise science, and human performance research.^(1)While once conceptual, its applicat...Artificial intelligence(AI) has rapidly transformed from a promising computational tool to a central force in global healthcare, exercise science, and human performance research.^(1)While once conceptual, its applications today are increasingly tangible-powering diagnostic tools, enhancing training personalization, guiding rehabilitation strategies, and informing ethical governance in sport.^(2)The integration of AI in health and sports science mirrors a broader digital health revolution, and this special topic offers a compelling snapshot of how AI is reshaping the landscape of patient care, athlete monitoring, and scientific inquiry.展开更多
The widespread application of large language models(LLMs)has highlighted new security challenges and ethical concerns,attracting significant academic and societal attention.Analysis of the security vulnerabilities of ...The widespread application of large language models(LLMs)has highlighted new security challenges and ethical concerns,attracting significant academic and societal attention.Analysis of the security vulnerabilities of LLMs and their misuse in cybercrime reveals that their advanced text-generation capabilities pose serious threats to personal privacy,data security,and information integrity.In addition,the effectiveness of current LLM-based defense strategies has been reviewed and evaluated.This paper examines the social implications of LLMs and proposes future directions for enhancing their security applications and ethical governance,aiming to inform the development of the field.展开更多
The concept of Digital Earth(DE)was formalized by Al Gore in 1998.At that time the technologies needed for its implementation were in an embryonic stage and the concept was quite visionary.Since then digital technolog...The concept of Digital Earth(DE)was formalized by Al Gore in 1998.At that time the technologies needed for its implementation were in an embryonic stage and the concept was quite visionary.Since then digital technologies have progressed significantly and their speed and pervasiveness have generated and are still causing the digital transformation of our society.This creates new opportunities and challenges for the realization of DE.‘What is DE today?’,‘What could DE be in the future?’,and‘What is needed to make DE a reality?’.To answer these questions it is necessary to examine DE considering all the technological,scientific,social,and economic aspects,but also bearing in mind the principles that inspired its formulation.By understanding the lessons learned from the past,it becomes possible to identify the remaining scientific and technological challenges,and the actions needed to achieve the ultimate goal of a‘Digital Earth for all’.This article reviews the evolution of the DE vision and its multiple definitions,illustrates what has been achieved so far,explains the impact of digital transformation,illustrates the new vision,and concludes with possible future scenarios and recommended actions to facilitate full DE implementation.展开更多
基金funded by the Shanghai Philosophy and Social Science Planning Project (2021BZX008)the National Social Science Foundation of China (23BZX110)the National Office for Philosophy and Social Science (20&ZD045).
文摘Background Clinical brain-computer interface(BCI)for mental disorders is an emerging interdisciplinary research field,posing new ethical concerns and challenges,yet lacking practical ethical governance guidelines for stakeholders and the entire community.Aims This study aims to establish a multidisciplinary consensus of principles for ethical governance of clinical BCI research for mental disorders and offer practical ethical guidance to stakeholders involved.Methods A systematic literature review,symposium and roundtable discussions,and a pre-Delphi(round 0)survey were conducted to form the questionnaire for the three-round modified Delphi study.Two rounds of surveys,followed by a third round of independent interviews of 25 experts from BCI-related research domains,were involved.We conducted quantitative analysis of responses and agreements among experts to reveal the consensus and differences regarding the ethical governance of mental BCI research from a multidisciplinary perspective.Results The Delphi panel emphasised important concerns of ethical review practices and ethical principles within the BCI context,identified qualified and highly influential institutions and personnel in conducting and advancing clinical BCI research,and recognised prioritised aspects in the risk-benefit evaluation.Experts expressed diverse opinions on specific ethical concerns,including concerns about invasive technology,its impact on humanity and potential social consequences.Agreement was reached that the practices of ethical governance of clinical BCI for mental disorders should focus on patient voluntariness,autonomy,long-term effects and related assessments of BCI interventions,as well as privacy protection,transparent reporting and ensuring that the research is conducted in qualified institutions with strong data security.Conclusions Ethical governance of clinical research on BCI for mental disorders should include interdisciplinary experts to balance various needs and incorporate the expertise of different stakeholders to avoid serious ethical issues.It requires scientifically grounded approaches,continuous monitoring and interdisciplinary collaboration to ensure evidence-based policies,comprehensive risk assessments and transparency,thereby promoting responsible innovations and protecting patient rights and well-being.
基金Water Security and Sustainable Development Hub funded by the UK Research and Innovation's Global Challenges Research Fund(GCRF),Grant/Award Number:ES/S008179/1。
文摘Values of individuals and organizations involved in decision-making processes form the basis for prioritizing outcomes in water governance.The novelty of this study lies in applying values to a specific decision-making context.It aims to assess the prioritized water governance outcomes and the underlying value systems shaping the actions of the primary water utility responsible for water governance in Delhi,the Delhi Jal Board(DJB).The paper will critically examine the policies and acts of the DJB that drive water governance in Delhi at present,utilizing a values-based framework in conjunction with secondary literature and expert interviews,to draw a picture of the values reflected.The study does not substantiate the notion of economic values dominating the water-related deci-sions;rather,recent policy guidelines indicate prioritization of equitable and fair distribution of water.Findings of this paper show that making the values explicit is largely disregarded in formulating water acts and policies,and values are never elucidated in the public domain,doing which can encourage water policies and practices that are socially,economically,and ecologically viable in the long run.It is expected that this paper will generate a discussion on water values being an integral part of water governance discourses.
基金supported by the National Key Research and Development Program(Grant No.2024YFA0917200)the Projects of the Chinese Center for Disease Control and Prevention(Grant No.BB2110240093)World Medical History under the Education Innovation Plan of the University of Science and Technology of China(Grant No.2024YCHX07).
文摘Background:With the rapid development of modern emerging technologies,the ethical dilemmas and social controversies triggered by scientific and technological activities have become increasingly prominent.How to guide technology for good and prevent and control technological risks has become an important issue of global concern.Research on science and technology ethics is dedicated to integrating ethical theories into governance practices and constructing ethical models that adapt to the development of the times.Methods:This article systematically reviews the six core approaches of scientific and technological ethics thought,including technological autonomy and political philosophy criticism,responsibility ethics and intergenerational obligations,technological intermediation and the integration of life and the world,ethical principles and normative frameworks,participatory governance and ethical practice innovation,as well as domain-specific ethical norms,thereby constructing an ethical analysis framework applicable to medical technology risks.And cross-analysis was conducted by taking medical events such as gene editing and xenotransplantation as examples.Results:Research shows that a single ethical approach has limitations in addressing complex medical ethical challenges,while the six approaches are complementary and synergistic.By criticizing technological autonomy,establishing a responsibility ethics orientation,setting the bottom line of ethical principles,promoting participatory governance,formulating domain norms,and continuously reflecting on the intermediary nature of technology,a multi-level and dynamically adaptive governance system for scientific and technological ethics can be constructed.Conclusion:The key to addressing contemporary medical ethics challenges lies in the comprehensive application of science and technology ethics theories and the integration of ethical considerations throughout the entire process of scientific and technological research and development.In the future,a governance framework that adapts to the development of new technologies should be established to promote cross-cultural and cross-disciplinary ethical dialogue and public participation,ensuring that scientific and technological innovation always serves the dignity of human life and overall well-being.
基金supported by the Ministry of Science and Tech-nology of the People's Republic of China(2021ZD0201900),Project 5(2021ZD0201905).
文摘Brain-computer interface(BCI)technology is rapidly advancing in medical research and application.As an emerging biomedical engineering technology,it has garnered significant attention in the clinical research of brain disease diagnosis and treatment,neurological rehabilitation,and mental health.However,BCI also raises several challenges and ethical concerns in clinical research.In this article,the authors investigate and discuss three aspects of BCI in medicine and healthcare:the state of international ethical governance,multidimensional ethical challenges pertaining to BCI in clinical research,and suggestive concerns for ethical review.Despite the great potential of frontier BCI research and development in the field of medical care,the ethical challenges induced by itself and the complexities of clinical research and brain function have put forward new special fields for ethics in BCI.To ensure"responsible innovation"in BCI research in healthcare and medicine,the creation of an ethical global governance framework and system,along with special guidelines for cutting-edge BCI research in medicine,is suggested.
文摘The 23rd meeting of the Central Committee for Comprehensively Deepening Reform, presided over by General Secretary Xi Jinping, adopted the Guiding Opinions on Strengthening the Governance of Science and Technology Ethics on 17 December 2021. On 20March 2022, the General Office of the CPC Central Committee and the General Office of the State Council issued the Opinions on Strengthening the Governance of Science and Technology Ethics.
文摘Artificial intelligence(AI) has rapidly transformed from a promising computational tool to a central force in global healthcare, exercise science, and human performance research.^(1)While once conceptual, its applications today are increasingly tangible-powering diagnostic tools, enhancing training personalization, guiding rehabilitation strategies, and informing ethical governance in sport.^(2)The integration of AI in health and sports science mirrors a broader digital health revolution, and this special topic offers a compelling snapshot of how AI is reshaping the landscape of patient care, athlete monitoring, and scientific inquiry.
基金Beijing Key Laboratory of Behavior and Mental Health,Peking University,China.
文摘The widespread application of large language models(LLMs)has highlighted new security challenges and ethical concerns,attracting significant academic and societal attention.Analysis of the security vulnerabilities of LLMs and their misuse in cybercrime reveals that their advanced text-generation capabilities pose serious threats to personal privacy,data security,and information integrity.In addition,the effectiveness of current LLM-based defense strategies has been reviewed and evaluated.This paper examines the social implications of LLMs and proposes future directions for enhancing their security applications and ethical governance,aiming to inform the development of the field.
文摘The concept of Digital Earth(DE)was formalized by Al Gore in 1998.At that time the technologies needed for its implementation were in an embryonic stage and the concept was quite visionary.Since then digital technologies have progressed significantly and their speed and pervasiveness have generated and are still causing the digital transformation of our society.This creates new opportunities and challenges for the realization of DE.‘What is DE today?’,‘What could DE be in the future?’,and‘What is needed to make DE a reality?’.To answer these questions it is necessary to examine DE considering all the technological,scientific,social,and economic aspects,but also bearing in mind the principles that inspired its formulation.By understanding the lessons learned from the past,it becomes possible to identify the remaining scientific and technological challenges,and the actions needed to achieve the ultimate goal of a‘Digital Earth for all’.This article reviews the evolution of the DE vision and its multiple definitions,illustrates what has been achieved so far,explains the impact of digital transformation,illustrates the new vision,and concludes with possible future scenarios and recommended actions to facilitate full DE implementation.
