Thread-embedding materials buried into acupuncture points to produce a long-time stimulation is a method which has been widely applied in the acupuncture and moxibustion therapies for diseases treating and they should...Thread-embedding materials buried into acupuncture points to produce a long-time stimulation is a method which has been widely applied in the acupuncture and moxibustion therapies for diseases treating and they should have excellent properties of good biocompatibility,biodegradability and moderate rigidity.Polyactic acid(PLA) as the thread-embedding material had some shortcomings such as poor hydrophilicity and slowly biodegradable speed.In this paper,PLA thread-embedding material was modified by chitosan coating which could improve rigidity,hydrophilicity and moisture absorption and thus produce better stimulation effect.The variation tendency of diameter,mass,hydrophilicity,and initial modulus of the sample under the change of chitosan coating concentration,coating time and coating times were studied respectively.The results showed that the hydrophilicity,mass,and initial modulus after coating rose in a certain range when the coating time,coating times and coating concentration increased,while the changing of coating had little impact on fiber diameter.展开更多
Objective:To explore the clinical effect of embedding thread combined with Jianpi Qushi Huayu ointment in the treatment of bronchiectasis in remission period,and to observe the effect on the level of inflammatory cyto...Objective:To explore the clinical effect of embedding thread combined with Jianpi Qushi Huayu ointment in the treatment of bronchiectasis in remission period,and to observe the effect on the level of inflammatory cytokines.Methods:150 patients with bronchiectasis in remission period were divided into three groups(50 cases in each group),western medicine group(treated with salmeterol fluticasone and low dose erythromycin),combined group(treated with Jianpi Qushi Huayu plaster),observation group(treated with western medicine+Jianpi Qushi Huayu plaster+embedding thread),and the clinical treatment of the three groups were compared.Result:before and after treatment,the improvement of TCM syndrome score,the improvement of pulmonary ventilation index,the improvement of inflammatory cytokines,and the change of adverse reactions.Results:the treatment efficiency of the observation group and the combination group was significantly higher than that of the western medicine group P The peak level of expiratory flow velocity,the maximum expiratory flow,the forced expiratory volume in one second and the ratio of forced expiratory volume in one second to vital capacity in the observation group and the combined group were significantly better than those in the western medicine group and the pre-treatment level(P<0.05),and the improvement in the observation group was better than that in the combined group After treatment,the expression of IL-13,IL-10 and IL-4 in the combined group was significantly better than that in the western medicine group and before treatment(P<0.05),and the improvement in the observation group was better than that in the combined group;there was no significant difference in the incidence of adverse reactions among the three groups(P>0.05).Conclusion:catgut embedding combined with Jianpi Qushi Huayu ointment can significantly alleviate the related clinical symptoms and signs,effectively control the further aggravation of the disease,improve the lung function of patients,regulate the level of inflammatory cytokines to reduce the degree of inflammatory reaction,and do not significantly aggravate the adverse reactions of drugs.展开更多
BACKGROUND A total of 100 patients diagnosed with mixed hemorrhoids from October 2022 to September 2023 in our hospital were randomly divided into groups by dice rolling and compared with the efficacy of different tre...BACKGROUND A total of 100 patients diagnosed with mixed hemorrhoids from October 2022 to September 2023 in our hospital were randomly divided into groups by dice rolling and compared with the efficacy of different treatment options.AIM To analyze the clinical effect and prognosis of mixed hemorrhoids treated with polidocanol injection combined with automatic elastic thread ligation operation(RPH).METHODS A total of 100 patients with mixed hemorrhoids who visited our hospital from October 2022 to September 2023 were selected and randomly divided into the control group(n=50)and the treatment group(n=50)by rolling the dice.The procedure for prolapse and hemorrhoids(PPH)was adopted in the control group,while polidocanol foam injection+RPH was adopted in the treatment group.The therapeutic effects,operation time,wound healing time,hospital stay,pain situation(24 hours post-operative pain score,first defecation pain score),quality of life(QOL),incidence of complications(post-operative hemorrhage,edema,infection),incidence of anal stenosis 3 months post-operatively and recurrence rate 1 year post-operatively of the two groups were compared.RESULTS Compared with the control group,the total effective rate of treatment group was higher,and the difference was significant(P<0.05).The operation time/wound healing time/hospital stay in the treatment group were shorter than those in the control group(P<0.05).The pain scores at 24 hours after operation/first defecation pain score of the treatment group was significantly lower than those in the control group(P<0.05).After surgery,the QOL scores of the two groups decreased,with the treatment group having higher scores than that of the control group(P<0.05).Compared with the control group,the incidence of postoperative complications in the treatment group was lower,and the difference was significant(P<0.05);However,there was no significant difference in the incidence of postoperative bleeding between the two groups(P>0.05);There was no significant difference in the incidence of anal stenosis 3 months after operation and the recurrence rate 1 year after operation between the two groups(P>0.05).CONCLUSION For patients with mixed hemorrhoids,the therapeutic effect achieved by using polidocanol injection combined with RPH was better.The wounds of the patients healed faster,the postoperative pain was milder,QOL improved,and the incidence of complications was lower,and the short-term and long-term prognosis was good.展开更多
Let G be a group.The family of all sets which are closed in every Hausdorf group topology of G form the family of closed sets of a T_(1) topology M_(G) on G called the Markov topology.Similarly,the family of all algeb...Let G be a group.The family of all sets which are closed in every Hausdorf group topology of G form the family of closed sets of a T_(1) topology M_(G) on G called the Markov topology.Similarly,the family of all algebraic subsets of G forms a family of closed sets for another T_(1)topology Z_(G) on G called the Zarski topology.A subgroup H of G is said to be Markov(resp.Zarski)embedded if the equality M_(G|H)=M_(H)(resp.Z_(G|H)=Z_(H))holds.I's proved that an abirary subgroup of a free group is both Zariski and Markov embedded in it.展开更多
BACKGROUND Intraoperative determination of resection margin and adequate residual liver parenchyma are the key points of hepatectomy for the treatment of liver tumors.Intraoperative ultrasound and indocyanine green fl...BACKGROUND Intraoperative determination of resection margin and adequate residual liver parenchyma are the key points of hepatectomy for the treatment of liver tumors.Intraoperative ultrasound and indocyanine green fluorescence navigation are the most commonly used methods at present,but the technical barriers limit their promotion.AIM To evaluate the value of the three-dimensional location approach with silk thread(3D-LAST)in precise resection of liver tumors.METHODS From September 2020 to January 2022,8 patients with liver tumors including hepatocellular carcinoma,intrahepatic cholangiocarcinoma,hilar cholangiocar-cinoma,and gastric cancer liver metastasis were included in this study.All patients underwent 3D-LAST in precise resection of liver tumors.RESULTS All patients(8/8,100%)underwent the operation successfully without any complications.During the mean follow-up of 8.7 months,all patients survived without tumor recurrence.CONCLUSION In conclusion,the 3D-LAST is a safe and effective new method for liver intraop-erative navigation,which is practical and easy to promote.Core Tip:The aim of this study is to evaluate the value of the three-dimensional location approach with silk thread(3D-LAST)in precise resection of liver tumors.Eight patients with liver tumors including hepatocellular carcinoma,intrahepatic cholangiocarcinoma,hilar cholangiocarcinoma,and gastric cancer liver metastasis underwent the operation successfully without any complications.During the mean follow-up of 8.7 months,all patients survived without tumor recurrence.In conclusion,the 3D-LAST is a safe and effective new method for liver intraoperative navigation,which is practical and easy to promote.INTRODUCTION Hepatectomy is widely used for the treatment of liver tumors.In recent decades,the concept and practice of hepatectomy have developed from irregular,regular and anatomical to the current precise resection.Necessary assistive technologies have enabled these advances.Intraoperative ultrasound(IOUS)localization and indocyanine green(ICG)fluorescence imaging guidance are two frequently-used approaches for laparoscopic hepatectomy[1,2].IOUS is an invaluable auxiliary means widely accepted in surgery for real-time diagnostic information to determine resection range and navigate the surgical path[3].However,the major limitation of IOUS is the time cost during the procedure for paging the sono-graphers and the difficulty of deciphering two dimensional images[4].ICG is a non-toxic water-soluble fluorophore that reveals fluorescence under the near-infrared spectrum[5].Since liver tissue penetration is limited to 5 to 10 mm,that restricted the visualization of deeper tumors by ICG excitation,thereby interfering with its application in laparoscopic hepatectomy[6].IOUS and ICG navigation require specific technical equipment,making implementation difficult in many centers.And these techniques will significantly increase the operation time.Three-dimensional(3D)visualization involves extracting features and producing volumetric images based on computed tomography(CT)through a computer postprocessing technique.This tool offers a reasonable approach to the clinical decision for the potential to display the complex internal anatomy in an intuitive and stereoscopic manner[7].In the past few decades,applying 3D simulation software for liver volume calculation,virtual simulation surgery,portal hypertension monitor,and surgical navigation has proven to be safe and effective[8].Therefore,we propose a new method to find obvious anatomical markers and calculate the resection range according to 3D positioning before operation.During the operation,the scope of resection was delineated with silk thread,and resection was performed.This is a new practical approach,which we named as 3D location approach with silk thread(3D-LAST).RESULTS During the study period from September 2020 to January 2022,5 patients with hepatocellular carcinoma,1 patient with intrahepatic cholangiocarcinoma,1 patient with hilar cholangiocarcinoma,and 1 patient with gastric cancer liver metastasis were assessed for liver resection.There were 5 males and 3 females.The mean age of these patients was 54.3±10.2 years(34-66 years).Preoperative 3D positioning was conducted and the scope of resection was delineated with a surgical suture successfully performed in all 8 patients without complications.The treatment results of these 8 patients are shown in Table 1.The 90-day operative mortality was zero.Complications worse than Dindo-Clavien IIIa was not observed at a mean follow-up time of 8.7 months(4-16 months),there was no evidence of tumor recurrence or extrahepatic metastasis.At the time of reporting,the patients are all alive and lead normal lives.We take one patient as an example,58-year-old male,who found a liver lesion 10 months after gastric cancer surgery.Enhanced CT showed that the lesion was located in the liver S5,about 1.5 cm in diameter,and considered metastatic lesions.We performed 3D-LAST guided hepatectomy on this patient(Figure 1).Other representative 3D-LAST surgical procedures are shown in Figure 2.展开更多
In petroleum extraction,the sealing surfaces of bolted joints are susceptible to damage due to the high-temperature and high-pressure conditions in wellbores.This damage adversely affects sealing performance,consequen...In petroleum extraction,the sealing surfaces of bolted joints are susceptible to damage due to the high-temperature and high-pressure conditions in wellbores.This damage adversely affects sealing performance,consequently leading to the failure and damage of threaded connections.In severe cases,it can result in considerable economic losses and trigger safety accidents.The sealing performance of special bolted joints holds crucial importance for production efficiency,output,equipment lifespan,and cost control.Enhancing the sealing perfor-mance of threaded connections can have a positive impact on industrial production and environmental protection.The existing research on American Petroleum Institute threaded joints has been thorough and has obtained a series of excellent results.However,the research on the sealing damage mechanism of threaded connections under complex well conditions lacks sufficient depth and that on new sealing technology is scarce.This study proposes a half-size evaluation test to address the abovementioned problem.Based on this test,an investigation into the sealing performance of threaded connections under high-temperature,cyclic loading,and high-temperature creep conditions is conducted.This study uses a combined approach of finite element methods and experiments to investigate the impact of different makeup torques on the sealing performance of premium threaded connections(PTCs).The results of the half-size evaluation test indicate that temperature notably influences the sealing performance of threaded connections.The continuous action of high temperatures causes contact pressure and sealing performance to decrease,and sealing contact pressure increases after cooling.Finite element and test results show that for a certain joint A,the greater the torque,the higher the critical sealing pressure of the thread,and the better the sealing performance.The research on the sealing damage mechanism of PTCs provides a scientific basis and theoretical guidance for the further optimization and development of PTCs.展开更多
Tibetan medical named entity recognition(Tibetan MNER)involves extracting specific types of medical entities from unstructured Tibetan medical texts.Tibetan MNER provide important data support for the work related to ...Tibetan medical named entity recognition(Tibetan MNER)involves extracting specific types of medical entities from unstructured Tibetan medical texts.Tibetan MNER provide important data support for the work related to Tibetan medicine.However,existing Tibetan MNER methods often struggle to comprehensively capture multi-level semantic information,failing to sufficiently extract multi-granularity features and effectively filter out irrelevant information,which ultimately impacts the accuracy of entity recognition.This paper proposes an improved embedding representation method called syllable-word-sentence embedding.By leveraging features at different granularities and using un-scaled dot-product attention to focus on key features for feature fusion,the syllable-word-sentence embedding is integrated into the transformer,enhancing the specificity and diversity of feature representations.The model leverages multi-level and multi-granularity semantic information,thereby improving the performance of Tibetan MNER.We evaluate our proposed model on datasets from various domains.The results indicate that the model effectively identified three types of entities in the Tibetan news dataset we constructed,achieving an F1 score of 93.59%,which represents an improvement of 1.24%compared to the vanilla FLAT.Additionally,results from the Tibetan medical dataset we developed show that it is effective in identifying five kinds of medical entities,with an F1 score of 71.39%,which is a 1.34%improvement over the vanilla FLAT.展开更多
A complete examination of Large Language Models’strengths,problems,and applications is needed due to their rising use across disciplines.Current studies frequently focus on single-use situations and lack a comprehens...A complete examination of Large Language Models’strengths,problems,and applications is needed due to their rising use across disciplines.Current studies frequently focus on single-use situations and lack a comprehensive understanding of LLM architectural performance,strengths,and weaknesses.This gap precludes finding the appropriate models for task-specific applications and limits awareness of emerging LLM optimization and deployment strategies.In this research,50 studies on 25+LLMs,including GPT-3,GPT-4,Claude 3.5,DeepKet,and hybrid multimodal frameworks like ContextDET and GeoRSCLIP,are thoroughly reviewed.We propose LLM application taxonomy by grouping techniques by task focus—healthcare,chemistry,sentiment analysis,agent-based simulations,and multimodal integration.Advanced methods like parameter-efficient tuning(LoRA),quantumenhanced embeddings(DeepKet),retrieval-augmented generation(RAG),and safety-focused models(GalaxyGPT)are evaluated for dataset requirements,computational efficiency,and performance measures.Frameworks for ethical issues,data limited hallucinations,and KDGI-enhanced fine-tuning like Woodpecker’s post-remedy corrections are highlighted.The investigation’s scope,mad,and methods are described,but the primary results are not.The work reveals that domain-specialized fine-tuned LLMs employing RAG and quantum-enhanced embeddings performbetter for context-heavy applications.In medical text normalization,ChatGPT-4 outperforms previous models,while two multimodal frameworks,GeoRSCLIP,increase remote sensing.Parameter-efficient tuning technologies like LoRA have minimal computing cost and similar performance,demonstrating the necessity for adaptive models in multiple domains.To discover the optimum domain-specific models,explain domain-specific fine-tuning,and present quantum andmultimodal LLMs to address scalability and cross-domain issues.The framework helps academics and practitioners identify,adapt,and innovate LLMs for different purposes.This work advances the field of efficient,interpretable,and ethical LLM application research.展开更多
Named Entity Recognition(NER)is vital in natural language processing for the analysis of news texts,as it accurately identifies entities such as locations,persons,and organizations,which is crucial for applications li...Named Entity Recognition(NER)is vital in natural language processing for the analysis of news texts,as it accurately identifies entities such as locations,persons,and organizations,which is crucial for applications like news summarization and event tracking.However,NER in the news domain faces challenges due to insufficient annotated data,complex entity structures,and strong context dependencies.To address these issues,we propose a new Chinesenamed entity recognition method that integrates transfer learning with word embeddings.Our approach leverages the ERNIE pre-trained model for transfer learning and obtaining general language representations and incorporates the Soft-lexicon word embedding technique to handle varied entity structures.This dual-strategy enhances the model’s understanding of context and boosts its ability to process complex texts.Experimental results show that our method achieves an F1 score of 94.72% on a news dataset,surpassing baseline methods by 3%–4%,thereby confirming its effectiveness for Chinese-named entity recognition in the news domain.展开更多
As the global textile market continues to expand, demand for sewing threads-a critical auxiliary material-is rising. In recent years, automotive interiors, smart outdoor equipment, and medical and ecofriendly products...As the global textile market continues to expand, demand for sewing threads-a critical auxiliary material-is rising. In recent years, automotive interiors, smart outdoor equipment, and medical and ecofriendly products have emerged as new growth engines for the textile industry. This has propelled specialized niche markets for sewing threads designed for these applications, revealing significant and undeniable potential.展开更多
In the domain of knowledge graph embedding,conventional approaches typically transform entities and relations into continuous vector spaces.However,parameter efficiency becomes increasingly crucial when dealing with l...In the domain of knowledge graph embedding,conventional approaches typically transform entities and relations into continuous vector spaces.However,parameter efficiency becomes increasingly crucial when dealing with large-scale knowledge graphs that contain vast numbers of entities and relations.In particular,resource-intensive embeddings often lead to increased computational costs,and may limit scalability and adaptability in practical environ-ments,such as in low-resource settings or real-world applications.This paper explores an approach to knowledge graph representation learning that leverages small,reserved entities and relation sets for parameter-efficient embedding.We introduce a hierarchical attention network designed to refine and maximize the representational quality of embeddings by selectively focusing on these reserved sets,thereby reducing model complexity.Empirical assessments validate that our model achieves high performance on the benchmark dataset with fewer parameters and smaller embedding dimensions.The ablation studies further highlight the impact and contribution of each component in the proposed hierarchical attention structure.展开更多
The increasing fluency of advanced language models,such as GPT-3.5,GPT-4,and the recently introduced DeepSeek,challenges the ability to distinguish between human-authored and AI-generated academic writing.This situati...The increasing fluency of advanced language models,such as GPT-3.5,GPT-4,and the recently introduced DeepSeek,challenges the ability to distinguish between human-authored and AI-generated academic writing.This situation is raising significant concerns regarding the integrity and authenticity of academic work.In light of the above,the current research evaluates the effectiveness of Bidirectional Long Short-TermMemory(BiLSTM)networks enhanced with pre-trained GloVe(Global Vectors for Word Representation)embeddings to detect AIgenerated scientific Abstracts drawn from the AI-GA(Artificial Intelligence Generated Abstracts)dataset.Two core BiLSTM variants were assessed:a single-layer approach and a dual-layer design,each tested under static or adaptive embeddings.The single-layer model achieved nearly 97%accuracy with trainable GloVe,occasionally surpassing the deeper model.Despite these gains,neither configuration fully matched the 98.7%benchmark set by an earlier LSTMWord2Vec pipeline.Some runs were over-fitted when embeddings were fine-tuned,whereas static embeddings offered a slightly lower yet stable accuracy of around 96%.This lingering gap reinforces a key ethical and procedural concern:relying solely on automated tools,such as Turnitin’s AI-detection features,to penalize individuals’risks and unjust outcomes.Misclassifications,whether legitimate work is misread as AI-generated or engineered text,evade detection,demonstrating that these classifiers should not stand as the sole arbiters of authenticity.Amore comprehensive approach is warranted,one which weaves model outputs into a systematic process supported by expert judgment and institutional guidelines designed to protect originality.展开更多
Objective:To explore the effects of acupoint catgut embedding combined with auricular point pressing with beans on symptom management self-efficacy and quality of life in patients with nonalcoholic steatohepatitis(NAS...Objective:To explore the effects of acupoint catgut embedding combined with auricular point pressing with beans on symptom management self-efficacy and quality of life in patients with nonalcoholic steatohepatitis(NASH)of liver depression and spleen deficiency type.Methods:Sixty patients with NASH of liver depression and spleen deficiency type admitted to our hospital from January 2021 to December 2023 were selected and divided into an acupoint catgut embedding group(n=30)and a combined group(n=30)using the envelope lottery method.The acupoint catgut embedding group received acupoint catgut embedding intervention,while the combined group received auricular point pressing with beans on the basis of the acupoint catgut embedding group.The two groups were compared in terms of TCM syndrome scores,symptom management self-efficacy[Chronic Disease Self-Efficacy Scale(CDSES)],and quality of life[Chronic Liver Disease Questionnaire(CLDQ)].Results:After intervention,the combined group had lower TCM syndrome scores for both primary and secondary symptoms compared to the acupoint catgut embedding group(P<0.05).The combined group also had higher scores in all dimensions and total score of the CDSES compared to the acupoint catgut embedding group(P<0.05).Similarly,the combined group had higher scores in all dimensions and total score of the CLDQ compared to the acupoint catgut embedding group(P<0.05).Conclusion:Acupoint catgut embedding combined with auricular point pressing with beans can effectively improve TCM symptoms,enhance symptom management self-efficacy,and improve quality of life in patients with NASH of liver depression and spleen deficiency type.展开更多
Constructing an in vitro vascularized liver tissue model that closely simulates the human liver is crucial for promoting cell proliferation,mimicking physiological heterogeneous structures,and recreating the cellular ...Constructing an in vitro vascularized liver tissue model that closely simulates the human liver is crucial for promoting cell proliferation,mimicking physiological heterogeneous structures,and recreating the cellular microenvironment.However,the layer-by-layer printing method is significantly constrained by the rheological properties of the bioink,making it challenging to form complex three-dimensional vascular structures in low-viscosity soft materials.To overcome this limitation,we developed a cross-linkable biphasic embedding medium by mixing low-viscosity biomaterials with gelatin microgel.This medium possesses yield stress and self-healing properties,facilitating efficient and continuous three-dimensional shaping of sacrificial ink within it.By adjusting the printing speed,we controlled the filament diameter,achieving a range from 250μm to 1000μm,and ensuring precise control over ink deposition locations and filament shapes.Using the in situ endothelialization method,we constructed complex vascular structures and ensured close adhesion between hepatocytes and endothelial cells.In vitro experiments demonstrated that the vascularized liver tissue model exhibited enhanced protein synthesis and metabolic function compared to mixed liver tissue.We also investigated the impact of varying vascular densities on liver tissue function.Transcriptome sequencing revealed that liver tissues with higher vascular density exhibited upregulated gene expression in metabolic and angiogenesis-related pathways.In summary,this method is adaptable to various materials,allowing the rheological properties of the supporting bath and the tissue's porosity to be modified using microgels,thus enabling precise regulation of the liver tissue microenvironment.Additionally,it facilitates the rapid construction of three-dimensional vascular structures within liver tissue.The resulting vascularized liver tissue model exhibits enhanced biological functionality,opening new opportunities for biomedical applications.展开更多
In this paper,by constructing the current graph of the complete graph K_(12s+9)and a mapping function,we prove that K_(12s+9)(s is an odd number)has at least 6^(2s)×3^(s+3/2) nonisomorphic orientable quadrangular...In this paper,by constructing the current graph of the complete graph K_(12s+9)and a mapping function,we prove that K_(12s+9)(s is an odd number)has at least 6^(2s)×3^(s+3/2) nonisomorphic orientable quadrangular embeddings,and the orientable genus is(12s+9)(12s+4)/8+1.Every one of the nonisomorphic orientable quadrangular embeddings has at least twenty-four 4-edge-colors,and each color appears around each face of orientable quadrangular embeddings.展开更多
Objective: The comparison of the remote and recent therapeutic effects on perennial allergic rhinitis was carried on among single application of acupoint-thread embedding, western medicine (certirizine+flixonase) and ...Objective: The comparison of the remote and recent therapeutic effects on perennial allergic rhinitis was carried on among single application of acupoint-thread embedding, western medicine (certirizine+flixonase) and allied therapy. Method: Ninety cases were randomized into thread-embedding group, western medicine group and embedding+western medicine group (allied-therapy group), 30 cases in each one. In thread embedding group, Yingxiang (迎香 LI 20) and Feishu (肺俞 BL 13) were selected for thread embedding, once a week, totally 4 treatments were required. In western medicine group, certirizine tablet 10 mg in combination with flixonase sprayer was applied once per day, continuously for 30 days in treatment. In allied-therapy group, both of the above methods were adopted continuously for 30 days in treatment. The therapeutic effects were in statistics at the end of treatment and 1 year later. Results: At the end of treatment, in thread-embedding group, 21 cases were remarkably effective, 3 cases effective and 6 cases no effect. In western medicine group, 20 cases were remarkably effective, 3 cases effective and 7 cases no effect. In allied-therapy group, 23 cases were remarkably effective, 2 cases effective and 5 cases no effect. It was shown in statistics that there was no significant difference in therapeutic effects among three groups ( P>0.05 ). But one year after the end of treatment, it was indicated that in thread-embedding group, 3 cases were remarkably effective, 10 cases effective and 17 cases no effect; in western medicine group, 2 cases were remarkably effective, 9 cases effective and 19 cases no effect; in allied-therapy group, 7 cases were remarkably effective, 11 cases effective and 12 cases no effect. The significant difference in the therapeutic effects had not been presented in the comparison between thread-embedding group and western medicine group (P>0.05), but that had been presented between allied-therapy group with either of the groups with single therapy applied (P<0.05). Conclusion: Quite good recent therapeutic effect of either acupoint-thread embedding or western medicine (certirizine+flixonase) was achieved on perennial allergic rhinitis. The remote therapeutic effect of allied therapy was more advantageous than that of single application of either thread embedding or western medicine.展开更多
Poly( glycolic acid-lactic acid)( PGLA) threadembedding material was modified by chitosan coating which could improve the rigidity,hydrophilicity and moisture absorption of the material,and produced better stimulation...Poly( glycolic acid-lactic acid)( PGLA) threadembedding material was modified by chitosan coating which could improve the rigidity,hydrophilicity and moisture absorption of the material,and produced better stimulation effect. Thus,this kind of thread-embedding materials which can be buried into acupuncture points to produce a long-time stimulation is popular in the acupuncture and moxibustion therapies. The variation tendencies of diameter,weight, hydrophilicity, and flexibility of the samples under the change of chitosan coating concentration,coating time and coating times were studied respectively. The results showed that the hydrophilicity,weight,and rigidity after coating rose in a certain range with the increase of coating time,coating times and coating concentration. The coating time had little influence on the diameter of fiber.展开更多
Aerodynamic surrogate modeling mostly relies only on integrated loads data obtained from simulation or experiment,while neglecting and wasting the valuable distributed physical information on the surface.To make full ...Aerodynamic surrogate modeling mostly relies only on integrated loads data obtained from simulation or experiment,while neglecting and wasting the valuable distributed physical information on the surface.To make full use of both integrated and distributed loads,a modeling paradigm,called the heterogeneous data-driven aerodynamic modeling,is presented.The essential concept is to incorporate the physical information of distributed loads as additional constraints within the end-to-end aerodynamic modeling.Towards heterogenous data,a novel and easily applicable physical feature embedding modeling framework is designed.This framework extracts lowdimensional physical features from pressure distribution and then effectively enhances the modeling of the integrated loads via feature embedding.The proposed framework can be coupled with multiple feature extraction methods,and the well-performed generalization capabilities over different airfoils are verified through a transonic case.Compared with traditional direct modeling,the proposed framework can reduce testing errors by almost 50%.Given the same prediction accuracy,it can save more than half of the training samples.Furthermore,the visualization analysis has revealed a significant correlation between the discovered low-dimensional physical features and the heterogeneous aerodynamic loads,which shows the interpretability and credibility of the superior performance offered by the proposed deep learning framework.展开更多
In this paper,we introduce the notion of embedding tensors on 3-Hom-Lie algebras and show that embedding tensors induce naturally 3-Hom-Leibniz algebras.Moreover,the cohomology theory of embedding tensors on 3-Hom-Lie...In this paper,we introduce the notion of embedding tensors on 3-Hom-Lie algebras and show that embedding tensors induce naturally 3-Hom-Leibniz algebras.Moreover,the cohomology theory of embedding tensors on 3-Hom-Lie algebras is defined.As an application,we show that if two linear deformations of an embedding tensor on a 3-Hom-Lie algebra are equivalent,then their infinitesimals belong to the same cohomology class in the first cohomology group.展开更多
A novel image encryption scheme based on parallel compressive sensing and edge detection embedding technology is proposed to improve visual security. Firstly, the plain image is sparsely represented using the discrete...A novel image encryption scheme based on parallel compressive sensing and edge detection embedding technology is proposed to improve visual security. Firstly, the plain image is sparsely represented using the discrete wavelet transform.Then, the coefficient matrix is scrambled and compressed to obtain a size-reduced image using the Fisher–Yates shuffle and parallel compressive sensing. Subsequently, to increase the security of the proposed algorithm, the compressed image is re-encrypted through permutation and diffusion to obtain a noise-like secret image. Finally, an adaptive embedding method based on edge detection for different carrier images is proposed to generate a visually meaningful cipher image. To improve the plaintext sensitivity of the algorithm, the counter mode is combined with the hash function to generate keys for chaotic systems. Additionally, an effective permutation method is designed to scramble the pixels of the compressed image in the re-encryption stage. The simulation results and analyses demonstrate that the proposed algorithm performs well in terms of visual security and decryption quality.展开更多
文摘Thread-embedding materials buried into acupuncture points to produce a long-time stimulation is a method which has been widely applied in the acupuncture and moxibustion therapies for diseases treating and they should have excellent properties of good biocompatibility,biodegradability and moderate rigidity.Polyactic acid(PLA) as the thread-embedding material had some shortcomings such as poor hydrophilicity and slowly biodegradable speed.In this paper,PLA thread-embedding material was modified by chitosan coating which could improve rigidity,hydrophilicity and moisture absorption and thus produce better stimulation effect.The variation tendency of diameter,mass,hydrophilicity,and initial modulus of the sample under the change of chitosan coating concentration,coating time and coating times were studied respectively.The results showed that the hydrophilicity,mass,and initial modulus after coating rose in a certain range when the coating time,coating times and coating concentration increased,while the changing of coating had little impact on fiber diameter.
基金2020 Hebei provincial research project of Chinese medicine(No.2020374)
文摘Objective:To explore the clinical effect of embedding thread combined with Jianpi Qushi Huayu ointment in the treatment of bronchiectasis in remission period,and to observe the effect on the level of inflammatory cytokines.Methods:150 patients with bronchiectasis in remission period were divided into three groups(50 cases in each group),western medicine group(treated with salmeterol fluticasone and low dose erythromycin),combined group(treated with Jianpi Qushi Huayu plaster),observation group(treated with western medicine+Jianpi Qushi Huayu plaster+embedding thread),and the clinical treatment of the three groups were compared.Result:before and after treatment,the improvement of TCM syndrome score,the improvement of pulmonary ventilation index,the improvement of inflammatory cytokines,and the change of adverse reactions.Results:the treatment efficiency of the observation group and the combination group was significantly higher than that of the western medicine group P The peak level of expiratory flow velocity,the maximum expiratory flow,the forced expiratory volume in one second and the ratio of forced expiratory volume in one second to vital capacity in the observation group and the combined group were significantly better than those in the western medicine group and the pre-treatment level(P<0.05),and the improvement in the observation group was better than that in the combined group After treatment,the expression of IL-13,IL-10 and IL-4 in the combined group was significantly better than that in the western medicine group and before treatment(P<0.05),and the improvement in the observation group was better than that in the combined group;there was no significant difference in the incidence of adverse reactions among the three groups(P>0.05).Conclusion:catgut embedding combined with Jianpi Qushi Huayu ointment can significantly alleviate the related clinical symptoms and signs,effectively control the further aggravation of the disease,improve the lung function of patients,regulate the level of inflammatory cytokines to reduce the degree of inflammatory reaction,and do not significantly aggravate the adverse reactions of drugs.
文摘BACKGROUND A total of 100 patients diagnosed with mixed hemorrhoids from October 2022 to September 2023 in our hospital were randomly divided into groups by dice rolling and compared with the efficacy of different treatment options.AIM To analyze the clinical effect and prognosis of mixed hemorrhoids treated with polidocanol injection combined with automatic elastic thread ligation operation(RPH).METHODS A total of 100 patients with mixed hemorrhoids who visited our hospital from October 2022 to September 2023 were selected and randomly divided into the control group(n=50)and the treatment group(n=50)by rolling the dice.The procedure for prolapse and hemorrhoids(PPH)was adopted in the control group,while polidocanol foam injection+RPH was adopted in the treatment group.The therapeutic effects,operation time,wound healing time,hospital stay,pain situation(24 hours post-operative pain score,first defecation pain score),quality of life(QOL),incidence of complications(post-operative hemorrhage,edema,infection),incidence of anal stenosis 3 months post-operatively and recurrence rate 1 year post-operatively of the two groups were compared.RESULTS Compared with the control group,the total effective rate of treatment group was higher,and the difference was significant(P<0.05).The operation time/wound healing time/hospital stay in the treatment group were shorter than those in the control group(P<0.05).The pain scores at 24 hours after operation/first defecation pain score of the treatment group was significantly lower than those in the control group(P<0.05).After surgery,the QOL scores of the two groups decreased,with the treatment group having higher scores than that of the control group(P<0.05).Compared with the control group,the incidence of postoperative complications in the treatment group was lower,and the difference was significant(P<0.05);However,there was no significant difference in the incidence of postoperative bleeding between the two groups(P>0.05);There was no significant difference in the incidence of anal stenosis 3 months after operation and the recurrence rate 1 year after operation between the two groups(P>0.05).CONCLUSION For patients with mixed hemorrhoids,the therapeutic effect achieved by using polidocanol injection combined with RPH was better.The wounds of the patients healed faster,the postoperative pain was milder,QOL improved,and the incidence of complications was lower,and the short-term and long-term prognosis was good.
基金Supported by the Grant-in-Aid for Scientific Research(C)by the Japan Society for the Promotion of Science(20K03615)。
文摘Let G be a group.The family of all sets which are closed in every Hausdorf group topology of G form the family of closed sets of a T_(1) topology M_(G) on G called the Markov topology.Similarly,the family of all algebraic subsets of G forms a family of closed sets for another T_(1)topology Z_(G) on G called the Zarski topology.A subgroup H of G is said to be Markov(resp.Zarski)embedded if the equality M_(G|H)=M_(H)(resp.Z_(G|H)=Z_(H))holds.I's proved that an abirary subgroup of a free group is both Zariski and Markov embedded in it.
文摘BACKGROUND Intraoperative determination of resection margin and adequate residual liver parenchyma are the key points of hepatectomy for the treatment of liver tumors.Intraoperative ultrasound and indocyanine green fluorescence navigation are the most commonly used methods at present,but the technical barriers limit their promotion.AIM To evaluate the value of the three-dimensional location approach with silk thread(3D-LAST)in precise resection of liver tumors.METHODS From September 2020 to January 2022,8 patients with liver tumors including hepatocellular carcinoma,intrahepatic cholangiocarcinoma,hilar cholangiocar-cinoma,and gastric cancer liver metastasis were included in this study.All patients underwent 3D-LAST in precise resection of liver tumors.RESULTS All patients(8/8,100%)underwent the operation successfully without any complications.During the mean follow-up of 8.7 months,all patients survived without tumor recurrence.CONCLUSION In conclusion,the 3D-LAST is a safe and effective new method for liver intraop-erative navigation,which is practical and easy to promote.Core Tip:The aim of this study is to evaluate the value of the three-dimensional location approach with silk thread(3D-LAST)in precise resection of liver tumors.Eight patients with liver tumors including hepatocellular carcinoma,intrahepatic cholangiocarcinoma,hilar cholangiocarcinoma,and gastric cancer liver metastasis underwent the operation successfully without any complications.During the mean follow-up of 8.7 months,all patients survived without tumor recurrence.In conclusion,the 3D-LAST is a safe and effective new method for liver intraoperative navigation,which is practical and easy to promote.INTRODUCTION Hepatectomy is widely used for the treatment of liver tumors.In recent decades,the concept and practice of hepatectomy have developed from irregular,regular and anatomical to the current precise resection.Necessary assistive technologies have enabled these advances.Intraoperative ultrasound(IOUS)localization and indocyanine green(ICG)fluorescence imaging guidance are two frequently-used approaches for laparoscopic hepatectomy[1,2].IOUS is an invaluable auxiliary means widely accepted in surgery for real-time diagnostic information to determine resection range and navigate the surgical path[3].However,the major limitation of IOUS is the time cost during the procedure for paging the sono-graphers and the difficulty of deciphering two dimensional images[4].ICG is a non-toxic water-soluble fluorophore that reveals fluorescence under the near-infrared spectrum[5].Since liver tissue penetration is limited to 5 to 10 mm,that restricted the visualization of deeper tumors by ICG excitation,thereby interfering with its application in laparoscopic hepatectomy[6].IOUS and ICG navigation require specific technical equipment,making implementation difficult in many centers.And these techniques will significantly increase the operation time.Three-dimensional(3D)visualization involves extracting features and producing volumetric images based on computed tomography(CT)through a computer postprocessing technique.This tool offers a reasonable approach to the clinical decision for the potential to display the complex internal anatomy in an intuitive and stereoscopic manner[7].In the past few decades,applying 3D simulation software for liver volume calculation,virtual simulation surgery,portal hypertension monitor,and surgical navigation has proven to be safe and effective[8].Therefore,we propose a new method to find obvious anatomical markers and calculate the resection range according to 3D positioning before operation.During the operation,the scope of resection was delineated with silk thread,and resection was performed.This is a new practical approach,which we named as 3D location approach with silk thread(3D-LAST).RESULTS During the study period from September 2020 to January 2022,5 patients with hepatocellular carcinoma,1 patient with intrahepatic cholangiocarcinoma,1 patient with hilar cholangiocarcinoma,and 1 patient with gastric cancer liver metastasis were assessed for liver resection.There were 5 males and 3 females.The mean age of these patients was 54.3±10.2 years(34-66 years).Preoperative 3D positioning was conducted and the scope of resection was delineated with a surgical suture successfully performed in all 8 patients without complications.The treatment results of these 8 patients are shown in Table 1.The 90-day operative mortality was zero.Complications worse than Dindo-Clavien IIIa was not observed at a mean follow-up time of 8.7 months(4-16 months),there was no evidence of tumor recurrence or extrahepatic metastasis.At the time of reporting,the patients are all alive and lead normal lives.We take one patient as an example,58-year-old male,who found a liver lesion 10 months after gastric cancer surgery.Enhanced CT showed that the lesion was located in the liver S5,about 1.5 cm in diameter,and considered metastatic lesions.We performed 3D-LAST guided hepatectomy on this patient(Figure 1).Other representative 3D-LAST surgical procedures are shown in Figure 2.
文摘In petroleum extraction,the sealing surfaces of bolted joints are susceptible to damage due to the high-temperature and high-pressure conditions in wellbores.This damage adversely affects sealing performance,consequently leading to the failure and damage of threaded connections.In severe cases,it can result in considerable economic losses and trigger safety accidents.The sealing performance of special bolted joints holds crucial importance for production efficiency,output,equipment lifespan,and cost control.Enhancing the sealing perfor-mance of threaded connections can have a positive impact on industrial production and environmental protection.The existing research on American Petroleum Institute threaded joints has been thorough and has obtained a series of excellent results.However,the research on the sealing damage mechanism of threaded connections under complex well conditions lacks sufficient depth and that on new sealing technology is scarce.This study proposes a half-size evaluation test to address the abovementioned problem.Based on this test,an investigation into the sealing performance of threaded connections under high-temperature,cyclic loading,and high-temperature creep conditions is conducted.This study uses a combined approach of finite element methods and experiments to investigate the impact of different makeup torques on the sealing performance of premium threaded connections(PTCs).The results of the half-size evaluation test indicate that temperature notably influences the sealing performance of threaded connections.The continuous action of high temperatures causes contact pressure and sealing performance to decrease,and sealing contact pressure increases after cooling.Finite element and test results show that for a certain joint A,the greater the torque,the higher the critical sealing pressure of the thread,and the better the sealing performance.The research on the sealing damage mechanism of PTCs provides a scientific basis and theoretical guidance for the further optimization and development of PTCs.
基金supported in part by the National Science and Technology Major Project under(Grant 2022ZD0116100)in part by the National Natural Science Foundation Key Project under(Grant 62436006)+4 种基金in part by the National Natural Science Foundation Youth Fund under(Grant 62406257)in part by the Xizang Autonomous Region Natural Science Foundation General Project under(Grant XZ202401ZR0031)in part by the National Natural Science Foundation of China under(Grant 62276055)in part by the Sichuan Science and Technology Program under(Grant 23ZDYF0755)in part by the Xizang University‘High-Level Talent Training Program’Project under(Grant 2022-GSP-S098).
文摘Tibetan medical named entity recognition(Tibetan MNER)involves extracting specific types of medical entities from unstructured Tibetan medical texts.Tibetan MNER provide important data support for the work related to Tibetan medicine.However,existing Tibetan MNER methods often struggle to comprehensively capture multi-level semantic information,failing to sufficiently extract multi-granularity features and effectively filter out irrelevant information,which ultimately impacts the accuracy of entity recognition.This paper proposes an improved embedding representation method called syllable-word-sentence embedding.By leveraging features at different granularities and using un-scaled dot-product attention to focus on key features for feature fusion,the syllable-word-sentence embedding is integrated into the transformer,enhancing the specificity and diversity of feature representations.The model leverages multi-level and multi-granularity semantic information,thereby improving the performance of Tibetan MNER.We evaluate our proposed model on datasets from various domains.The results indicate that the model effectively identified three types of entities in the Tibetan news dataset we constructed,achieving an F1 score of 93.59%,which represents an improvement of 1.24%compared to the vanilla FLAT.Additionally,results from the Tibetan medical dataset we developed show that it is effective in identifying five kinds of medical entities,with an F1 score of 71.39%,which is a 1.34%improvement over the vanilla FLAT.
文摘A complete examination of Large Language Models’strengths,problems,and applications is needed due to their rising use across disciplines.Current studies frequently focus on single-use situations and lack a comprehensive understanding of LLM architectural performance,strengths,and weaknesses.This gap precludes finding the appropriate models for task-specific applications and limits awareness of emerging LLM optimization and deployment strategies.In this research,50 studies on 25+LLMs,including GPT-3,GPT-4,Claude 3.5,DeepKet,and hybrid multimodal frameworks like ContextDET and GeoRSCLIP,are thoroughly reviewed.We propose LLM application taxonomy by grouping techniques by task focus—healthcare,chemistry,sentiment analysis,agent-based simulations,and multimodal integration.Advanced methods like parameter-efficient tuning(LoRA),quantumenhanced embeddings(DeepKet),retrieval-augmented generation(RAG),and safety-focused models(GalaxyGPT)are evaluated for dataset requirements,computational efficiency,and performance measures.Frameworks for ethical issues,data limited hallucinations,and KDGI-enhanced fine-tuning like Woodpecker’s post-remedy corrections are highlighted.The investigation’s scope,mad,and methods are described,but the primary results are not.The work reveals that domain-specialized fine-tuned LLMs employing RAG and quantum-enhanced embeddings performbetter for context-heavy applications.In medical text normalization,ChatGPT-4 outperforms previous models,while two multimodal frameworks,GeoRSCLIP,increase remote sensing.Parameter-efficient tuning technologies like LoRA have minimal computing cost and similar performance,demonstrating the necessity for adaptive models in multiple domains.To discover the optimum domain-specific models,explain domain-specific fine-tuning,and present quantum andmultimodal LLMs to address scalability and cross-domain issues.The framework helps academics and practitioners identify,adapt,and innovate LLMs for different purposes.This work advances the field of efficient,interpretable,and ethical LLM application research.
基金funded by Advanced Research Project(30209040702).
文摘Named Entity Recognition(NER)is vital in natural language processing for the analysis of news texts,as it accurately identifies entities such as locations,persons,and organizations,which is crucial for applications like news summarization and event tracking.However,NER in the news domain faces challenges due to insufficient annotated data,complex entity structures,and strong context dependencies.To address these issues,we propose a new Chinesenamed entity recognition method that integrates transfer learning with word embeddings.Our approach leverages the ERNIE pre-trained model for transfer learning and obtaining general language representations and incorporates the Soft-lexicon word embedding technique to handle varied entity structures.This dual-strategy enhances the model’s understanding of context and boosts its ability to process complex texts.Experimental results show that our method achieves an F1 score of 94.72% on a news dataset,surpassing baseline methods by 3%–4%,thereby confirming its effectiveness for Chinese-named entity recognition in the news domain.
文摘As the global textile market continues to expand, demand for sewing threads-a critical auxiliary material-is rising. In recent years, automotive interiors, smart outdoor equipment, and medical and ecofriendly products have emerged as new growth engines for the textile industry. This has propelled specialized niche markets for sewing threads designed for these applications, revealing significant and undeniable potential.
基金supported by the National Science and Technology Council(NSTC),Taiwan,under Grants Numbers 112-2622-E-029-009 and 112-2221-E-029-019.
文摘In the domain of knowledge graph embedding,conventional approaches typically transform entities and relations into continuous vector spaces.However,parameter efficiency becomes increasingly crucial when dealing with large-scale knowledge graphs that contain vast numbers of entities and relations.In particular,resource-intensive embeddings often lead to increased computational costs,and may limit scalability and adaptability in practical environ-ments,such as in low-resource settings or real-world applications.This paper explores an approach to knowledge graph representation learning that leverages small,reserved entities and relation sets for parameter-efficient embedding.We introduce a hierarchical attention network designed to refine and maximize the representational quality of embeddings by selectively focusing on these reserved sets,thereby reducing model complexity.Empirical assessments validate that our model achieves high performance on the benchmark dataset with fewer parameters and smaller embedding dimensions.The ablation studies further highlight the impact and contribution of each component in the proposed hierarchical attention structure.
文摘The increasing fluency of advanced language models,such as GPT-3.5,GPT-4,and the recently introduced DeepSeek,challenges the ability to distinguish between human-authored and AI-generated academic writing.This situation is raising significant concerns regarding the integrity and authenticity of academic work.In light of the above,the current research evaluates the effectiveness of Bidirectional Long Short-TermMemory(BiLSTM)networks enhanced with pre-trained GloVe(Global Vectors for Word Representation)embeddings to detect AIgenerated scientific Abstracts drawn from the AI-GA(Artificial Intelligence Generated Abstracts)dataset.Two core BiLSTM variants were assessed:a single-layer approach and a dual-layer design,each tested under static or adaptive embeddings.The single-layer model achieved nearly 97%accuracy with trainable GloVe,occasionally surpassing the deeper model.Despite these gains,neither configuration fully matched the 98.7%benchmark set by an earlier LSTMWord2Vec pipeline.Some runs were over-fitted when embeddings were fine-tuned,whereas static embeddings offered a slightly lower yet stable accuracy of around 96%.This lingering gap reinforces a key ethical and procedural concern:relying solely on automated tools,such as Turnitin’s AI-detection features,to penalize individuals’risks and unjust outcomes.Misclassifications,whether legitimate work is misread as AI-generated or engineered text,evade detection,demonstrating that these classifiers should not stand as the sole arbiters of authenticity.Amore comprehensive approach is warranted,one which weaves model outputs into a systematic process supported by expert judgment and institutional guidelines designed to protect originality.
文摘Objective:To explore the effects of acupoint catgut embedding combined with auricular point pressing with beans on symptom management self-efficacy and quality of life in patients with nonalcoholic steatohepatitis(NASH)of liver depression and spleen deficiency type.Methods:Sixty patients with NASH of liver depression and spleen deficiency type admitted to our hospital from January 2021 to December 2023 were selected and divided into an acupoint catgut embedding group(n=30)and a combined group(n=30)using the envelope lottery method.The acupoint catgut embedding group received acupoint catgut embedding intervention,while the combined group received auricular point pressing with beans on the basis of the acupoint catgut embedding group.The two groups were compared in terms of TCM syndrome scores,symptom management self-efficacy[Chronic Disease Self-Efficacy Scale(CDSES)],and quality of life[Chronic Liver Disease Questionnaire(CLDQ)].Results:After intervention,the combined group had lower TCM syndrome scores for both primary and secondary symptoms compared to the acupoint catgut embedding group(P<0.05).The combined group also had higher scores in all dimensions and total score of the CDSES compared to the acupoint catgut embedding group(P<0.05).Similarly,the combined group had higher scores in all dimensions and total score of the CLDQ compared to the acupoint catgut embedding group(P<0.05).Conclusion:Acupoint catgut embedding combined with auricular point pressing with beans can effectively improve TCM symptoms,enhance symptom management self-efficacy,and improve quality of life in patients with NASH of liver depression and spleen deficiency type.
基金the funding from the National Natural Science Foundation of China No.52275294the National Key Research and Development Program of China(No.2018YFA0703000)。
文摘Constructing an in vitro vascularized liver tissue model that closely simulates the human liver is crucial for promoting cell proliferation,mimicking physiological heterogeneous structures,and recreating the cellular microenvironment.However,the layer-by-layer printing method is significantly constrained by the rheological properties of the bioink,making it challenging to form complex three-dimensional vascular structures in low-viscosity soft materials.To overcome this limitation,we developed a cross-linkable biphasic embedding medium by mixing low-viscosity biomaterials with gelatin microgel.This medium possesses yield stress and self-healing properties,facilitating efficient and continuous three-dimensional shaping of sacrificial ink within it.By adjusting the printing speed,we controlled the filament diameter,achieving a range from 250μm to 1000μm,and ensuring precise control over ink deposition locations and filament shapes.Using the in situ endothelialization method,we constructed complex vascular structures and ensured close adhesion between hepatocytes and endothelial cells.In vitro experiments demonstrated that the vascularized liver tissue model exhibited enhanced protein synthesis and metabolic function compared to mixed liver tissue.We also investigated the impact of varying vascular densities on liver tissue function.Transcriptome sequencing revealed that liver tissues with higher vascular density exhibited upregulated gene expression in metabolic and angiogenesis-related pathways.In summary,this method is adaptable to various materials,allowing the rheological properties of the supporting bath and the tissue's porosity to be modified using microgels,thus enabling precise regulation of the liver tissue microenvironment.Additionally,it facilitates the rapid construction of three-dimensional vascular structures within liver tissue.The resulting vascularized liver tissue model exhibits enhanced biological functionality,opening new opportunities for biomedical applications.
文摘In this paper,by constructing the current graph of the complete graph K_(12s+9)and a mapping function,we prove that K_(12s+9)(s is an odd number)has at least 6^(2s)×3^(s+3/2) nonisomorphic orientable quadrangular embeddings,and the orientable genus is(12s+9)(12s+4)/8+1.Every one of the nonisomorphic orientable quadrangular embeddings has at least twenty-four 4-edge-colors,and each color appears around each face of orientable quadrangular embeddings.
文摘Objective: The comparison of the remote and recent therapeutic effects on perennial allergic rhinitis was carried on among single application of acupoint-thread embedding, western medicine (certirizine+flixonase) and allied therapy. Method: Ninety cases were randomized into thread-embedding group, western medicine group and embedding+western medicine group (allied-therapy group), 30 cases in each one. In thread embedding group, Yingxiang (迎香 LI 20) and Feishu (肺俞 BL 13) were selected for thread embedding, once a week, totally 4 treatments were required. In western medicine group, certirizine tablet 10 mg in combination with flixonase sprayer was applied once per day, continuously for 30 days in treatment. In allied-therapy group, both of the above methods were adopted continuously for 30 days in treatment. The therapeutic effects were in statistics at the end of treatment and 1 year later. Results: At the end of treatment, in thread-embedding group, 21 cases were remarkably effective, 3 cases effective and 6 cases no effect. In western medicine group, 20 cases were remarkably effective, 3 cases effective and 7 cases no effect. In allied-therapy group, 23 cases were remarkably effective, 2 cases effective and 5 cases no effect. It was shown in statistics that there was no significant difference in therapeutic effects among three groups ( P>0.05 ). But one year after the end of treatment, it was indicated that in thread-embedding group, 3 cases were remarkably effective, 10 cases effective and 17 cases no effect; in western medicine group, 2 cases were remarkably effective, 9 cases effective and 19 cases no effect; in allied-therapy group, 7 cases were remarkably effective, 11 cases effective and 12 cases no effect. The significant difference in the therapeutic effects had not been presented in the comparison between thread-embedding group and western medicine group (P>0.05), but that had been presented between allied-therapy group with either of the groups with single therapy applied (P<0.05). Conclusion: Quite good recent therapeutic effect of either acupoint-thread embedding or western medicine (certirizine+flixonase) was achieved on perennial allergic rhinitis. The remote therapeutic effect of allied therapy was more advantageous than that of single application of either thread embedding or western medicine.
基金Biomedical Textile Materials Science and Technology(111 Project),China(No.B07024)
文摘Poly( glycolic acid-lactic acid)( PGLA) threadembedding material was modified by chitosan coating which could improve the rigidity,hydrophilicity and moisture absorption of the material,and produced better stimulation effect. Thus,this kind of thread-embedding materials which can be buried into acupuncture points to produce a long-time stimulation is popular in the acupuncture and moxibustion therapies. The variation tendencies of diameter,weight, hydrophilicity, and flexibility of the samples under the change of chitosan coating concentration,coating time and coating times were studied respectively. The results showed that the hydrophilicity,weight,and rigidity after coating rose in a certain range with the increase of coating time,coating times and coating concentration. The coating time had little influence on the diameter of fiber.
基金supported by the National Natural Science Foundation of China(Nos.92152301,12072282)。
文摘Aerodynamic surrogate modeling mostly relies only on integrated loads data obtained from simulation or experiment,while neglecting and wasting the valuable distributed physical information on the surface.To make full use of both integrated and distributed loads,a modeling paradigm,called the heterogeneous data-driven aerodynamic modeling,is presented.The essential concept is to incorporate the physical information of distributed loads as additional constraints within the end-to-end aerodynamic modeling.Towards heterogenous data,a novel and easily applicable physical feature embedding modeling framework is designed.This framework extracts lowdimensional physical features from pressure distribution and then effectively enhances the modeling of the integrated loads via feature embedding.The proposed framework can be coupled with multiple feature extraction methods,and the well-performed generalization capabilities over different airfoils are verified through a transonic case.Compared with traditional direct modeling,the proposed framework can reduce testing errors by almost 50%.Given the same prediction accuracy,it can save more than half of the training samples.Furthermore,the visualization analysis has revealed a significant correlation between the discovered low-dimensional physical features and the heterogeneous aerodynamic loads,which shows the interpretability and credibility of the superior performance offered by the proposed deep learning framework.
基金Supported by the Scientific Research Foundation for Science&Technology Innovation Talent Team of the Intelligent Computing and Monitoring of Guizhou Province(Grant No.QJJ[2023]063)the Science and Technology Program of Guizhou Province(Grant Nos.ZK[2023]025+4 种基金QKHZC[2023]372ZK[2022]031)the National Natural Science Foundation of China(Grant No.12161013)the Scientific Research Foundation of Guizhou University of Finance and Economics(Grant No.2022KYYB08)the Doctoral Research Start-Up Fund of Guiyang University(Grant No.GYU-KY-2024).
文摘In this paper,we introduce the notion of embedding tensors on 3-Hom-Lie algebras and show that embedding tensors induce naturally 3-Hom-Leibniz algebras.Moreover,the cohomology theory of embedding tensors on 3-Hom-Lie algebras is defined.As an application,we show that if two linear deformations of an embedding tensor on a 3-Hom-Lie algebra are equivalent,then their infinitesimals belong to the same cohomology class in the first cohomology group.
基金supported by the Key Area R&D Program of Guangdong Province (Grant No.2022B0701180001)the National Natural Science Foundation of China (Grant No.61801127)+1 种基金the Science Technology Planning Project of Guangdong Province,China (Grant Nos.2019B010140002 and 2020B111110002)the Guangdong-Hong Kong-Macao Joint Innovation Field Project (Grant No.2021A0505080006)。
文摘A novel image encryption scheme based on parallel compressive sensing and edge detection embedding technology is proposed to improve visual security. Firstly, the plain image is sparsely represented using the discrete wavelet transform.Then, the coefficient matrix is scrambled and compressed to obtain a size-reduced image using the Fisher–Yates shuffle and parallel compressive sensing. Subsequently, to increase the security of the proposed algorithm, the compressed image is re-encrypted through permutation and diffusion to obtain a noise-like secret image. Finally, an adaptive embedding method based on edge detection for different carrier images is proposed to generate a visually meaningful cipher image. To improve the plaintext sensitivity of the algorithm, the counter mode is combined with the hash function to generate keys for chaotic systems. Additionally, an effective permutation method is designed to scramble the pixels of the compressed image in the re-encryption stage. The simulation results and analyses demonstrate that the proposed algorithm performs well in terms of visual security and decryption quality.
