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The Defects and Future Research Direction of the Auditof the Policy Implementation Effect 2 China 被引量:3
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作者 刘利 《石家庄经济学院学报》 2016年第3期97-99,共3页
近年来,政策执行效果审计在中国逐渐引起了关注.论文首先介绍了政策执行效果审计的内涵和研究的意义,在此基础上简要阐述了政策执行效果审计的发展现状,并指出了其缺陷,最后提出了未来的研究应重点关注建立政策执行效果审计理论框架体... 近年来,政策执行效果审计在中国逐渐引起了关注.论文首先介绍了政策执行效果审计的内涵和研究的意义,在此基础上简要阐述了政策执行效果审计的发展现状,并指出了其缺陷,最后提出了未来的研究应重点关注建立政策执行效果审计理论框架体系、完善政策执行效果审计评价指标体系、探索对政策本身的评价以及将政策执行效果审计与新兴互联网工程及信息技术结合起来等几个方面. 展开更多
关键词 政策执行效果审计 缺陷 研究方向
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Research on Innovation Effect of Mechanical Engineering and Its Automation
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作者 XIAXiaolin 《外文科技期刊数据库(文摘版)工程技术》 2022年第1期156-160,共5页
With the continuous development of society, the importance of mechanical engineering has gradually become prominent, which has also played a greater role in promoting the social economy. In the current social developm... With the continuous development of society, the importance of mechanical engineering has gradually become prominent, which has also played a greater role in promoting the social economy. In the current social development process, China has gradually accelerated the pace of industrial development, laying a solid foundation for ensuring a more stable development of the national economy. With the influence of internal environment and external environment, the innovation and development of mechanical intelligence is a problem that every country must face in the development process, and strengthening the innovation of mechanical engineering and its automation is an important way to better develop the country. However, limited by some factors in the development of mechanical automation, there is still a big gap between the actual development of the project and the ideal goal. Therefore, improving the innovation level of mechanical engineering automation in our country is the work content that must be perfected in the development process of our country. This article takes this as an example to analyze and discuss. 展开更多
关键词 mechanical engineering AUTOMATION INNOVATION effect research
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EXPERIMENTAL RESEARCH ON THE ANTI-CANCER IMMUNOMODULA-TIVE EFFECT OF THE POLYSOCOHARIBE-PEPTIDE OF CORIOLUS VERSICOLOR 被引量:1
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作者 许良中 杨庆尧 +4 位作者 周金煦 陈瑞婷 李晓玉 胡玉娟 王筠默 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 1989年第2期10-15,共6页
Polysocoharibe-peptide of Coriolus Versicolor (PSP) is a new anti-cancer immunomodulative drug. The present paper reports on the experimental research done with this drug. It was found that PSP had the ability to reco... Polysocoharibe-peptide of Coriolus Versicolor (PSP) is a new anti-cancer immunomodulative drug. The present paper reports on the experimental research done with this drug. It was found that PSP had the ability to recover hemolysin HC50, to increase the weight of the thymus, and increase the alexin of serum C3 and the IgG content of tumor bearing mice. FSP also significantly raised the pha-gocytic activity of macrophages in normal mice. PSP had a significant inhibitory effect on P38S and S180 cells. At the concentration of 1 mg/ml, PSP inhibited the proliferating activity of some human tumor call lines, such as SGC 7901, SPC, SLY and Mei. It had a direct toxic effect on SPC cells. PSP significantly inhibited the synthesis of nucleic acids of Ehrlich ascites carcinoma cells. In addition, PSP was antagonistic to the side effects of chemotherapy and radiotherapy. 展开更多
关键词 PSP EXPERIMENTAL research ON THE ANTI-CANCER IMMUNOMODULA-TIVE effect OF THE POLYSOCOHARIBE-PEPTIDE OF CORIOLUS VERSICOLOR SPC
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Comparative effectiveness research and health care reform in C hina
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作者 Yilong Wang Yongjun Wang 《Journal of Translational Neuroscience》 2016年第1期24-26,共3页
China has made significant progress in modernizing its healthcare system in the past 20 years. However, there are some issues that are difficult to solve on the current healthcare status, including the lack of medical... China has made significant progress in modernizing its healthcare system in the past 20 years. However, there are some issues that are difficult to solve on the current healthcare status, including the lack of medical care satisfaction in rural areas and urban areas, excessive consumption of medical resources, conflict and tension between the healthcare provider and patients, and the problems caused by the change of model of healthcare. Therefore, the State Council introduced the Opinions of the CPC Central Committee and the State Council on Deepening the Health Care System Reform in 2009 in order to provide basic, safe, effective, convenient and affordable healthcare for all residents. Despite the goals and policies set by the government, how to implement them remains to be challenging. Like evidence-based medicine, comparative effective research ( CER ) which started in the US in 2000 's can provide diagnosis and treatment information for patients, doctors, and health policy makers to make decisions on the effective ways of caring for both individual and population. It also may apply to the conditions of healthcare reform in China. And there are opportunities and challenges of conducting CER in our country. We suggest that the government should establish the national-level CER research institute, CER Leadership Committee and relevant standards, fund the CER projects, and begin CER in certain disciplines. 展开更多
关键词 healthcare comparative effective research (CER)
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Empirical Research of Farmer College Students' Learning Ability and Learning Effect in the Digital Environment
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作者 Jixian ZHANG 《Asian Agricultural Research》 2013年第8期108-113,118,共7页
In the course of training farmer college students,there have been a number of problems facing the modern distance education based on digital learning environment,such as weak learning adaptability and ability of farme... In the course of training farmer college students,there have been a number of problems facing the modern distance education based on digital learning environment,such as weak learning adaptability and ability of farmers and diverse learning needs.Using the empirical methods of questionnaire survey and interview,this article conducts an analysis of the farmer college students' digital learning ability and learning effect,and based on the theoretical study and practical achievements,explores some aspects,such as the information literacy and entrepreneurship ability training for farmer college students,the reform of course teaching and practice teaching,and the building of digital learning platform and special resources.And finally some innovative ideas and recommendations are put forth. 展开更多
关键词 LEARNING needs DIGITAL LEARNING ENVIRONMENT Learni
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Confounding Effect in Clinical Research of Otolaryngology and Its Control
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作者 Yong-qiang Yu Dong-yan Huang +7 位作者 Susan Armijo Olivo Huai-an Yang Yagesh Bambanini Lyn Sonnenberg Brenda Clark Gabriela Constantinescu Jason Qian Yu Ming Zhang 《Chinese Medical Sciences Journal》 CAS CSCD 2015年第2期121-130,共10页
Confounding effect is a critical issue in clinical research of otolaryngology because it can distort the research's conclusion. In this review, we introduce the definition of confounding effect, the methods of ver... Confounding effect is a critical issue in clinical research of otolaryngology because it can distort the research's conclusion. In this review, we introduce the definition of confounding effect, the methods of verifying and controlling the effect. Confounding effect can be prevented by research's design, and adjusted by data analysis. Clinicians would be aware and cautious about confounding effect in their research. They would be able to set up a research's design in which appropriate methods have been applied to prevent this effect.They would know how to adjust confounding effect after data collection. It is important to remember that sometimes it is impossible to eliminate confounding effect completely, and statistical method is not a master key. Solid research knowledge and critical thinking of our brain are the most important in controlling confounding effect. 展开更多
关键词 CLINICAL research OTOLARYNGOLOGY CONFOUNDING effect
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Researches on End Effects of Permanent Magnet Electromagnetic Launchers
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作者 MA Li-jun LIU Xiao-li LI Xiao-peng 《科技信息》 2013年第13期226-228,共3页
Brushless DC linear motors have considerable advantages of simpler structure,higher efficiency,higher thrust density and so on.They are well suited for many domains such as electromagnetic launch and launch-assist,but... Brushless DC linear motors have considerable advantages of simpler structure,higher efficiency,higher thrust density and so on.They are well suited for many domains such as electromagnetic launch and launch-assist,but it is inevitable that there exist longitudinal end effects in the mover of the motor caused by longitudinal discontinuities.The serious trouble caused by longitudinal end effects is the thrust ripple.Firstly,by using the method of finite element simulation,this paper studies the distribution of magnetic field and energy in the end region when the mover is in different positions in the range of a polar pitch and discusses the effective methods of reducing the longitudinal end effects.Then the law of the influence of different mover length on the longitudinal end effects has been studied by using analytic methods,and the influences of the mover length and its end geometry shape on the longitudinal end effects have been verified for the test model by using the method of finite element simulation. 展开更多
关键词 体育教育 体育精神 教学方法 体育教师 学生
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Henan Cultural Information Resources Sharing Project Persistent Effect Mechanism Research
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作者 Weigong CUI Hui JIAN +2 位作者 Yuan GAN Zhen ZHANG Yanfeng LIU 《Intelligent Information Management》 2009年第1期18-23,共6页
In order to reduce east--west section area of “digital divider” in China, Ministry of Culture laun- ches the National Cultural Information Resources Sharing Project in the mid-west provinces, and the state finance g... In order to reduce east--west section area of “digital divider” in China, Ministry of Culture laun- ches the National Cultural Information Resources Sharing Project in the mid-west provinces, and the state finance gives certain funds subsidy in the project construction period. Embarks highly from strategy during construction plan chosen and operational system management, as while as union digital library to construct a persistent effect mechanism. With the principle of state guidance, enterprise operation and benefit farmers, expand culture industry within the provincial and safeguard Cultural Information Resources Sharing Project sustainable development's, then promotes the rural economy culture full scale development. 展开更多
关键词 CULTURAL information resources SHARING project PERSISTENT effect mechanism research IPTV digital LIBRARY CULTURAL industry
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The Assessment of Non-Linear Effects in Clinical Research
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作者 Ton J. Cleophas Aeilko H. Zwinderman 《Pharmacology & Pharmacy》 2012年第2期139-147,共9页
Background: Novel models for the assessment of non-linear data are being developed for the benefit of making better predictions from the data. Objective: To review traditional and modern models. Results, and Conclusio... Background: Novel models for the assessment of non-linear data are being developed for the benefit of making better predictions from the data. Objective: To review traditional and modern models. Results, and Conclusions: 1) Logit and probit transformations are often successfully used to mimic a linear model. Logistic regression, Cox regression, Poisson regression, and Markow modeling are examples of logit transformation;2) Either the x- or y-axis or both of them can be logarithmically transformed. Also Box Cox transformation equations and ACE (alternating conditional expectations) or AVAS (additive and variance stabilization for regression) packages are simple empirical methods often successful for linearly remodeling of non-linear data;3) Data that are sinusoidal, can, generally, be successfully modeled using polynomial regression or Fourier analysis;4) For exponential patterns like plasma concentration time relationships exponential modeling with or without Laplace transformations is a possibility. Spline and Loess are computationally intensive modern methods, suitable for smoothing data patterns, if the data plot leaves you with no idea of the relationship between the y- and x-values. There are no statistical tests to assess the goodness of fit of these methods, but it is always better than that of traditional models. 展开更多
关键词 Non-Linear effects Clinical research Logit/Probit TRANSFORMATION Box Cox TRANSFORMATION ACE/AVAS Packages Curvilinear Data Spline MODELING LOESS MODELING
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Research on Replacing Effects & Examination System of TBT against Tariff Impediment to Textile and Apparel Trade
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作者 Chengjianbing1 Lvjianming2 Chengpeng Jiang3 1.Yiwu Bureau of Exit and Entry Inspection and Quarantine 2.Zhejiang Chinese Medical University 3. C.M.U. 《China Textile》 2010年第10期48-55,共8页
With the cutoff and limitation of tariff and traditional non-tariff Barriers to Trade by GATT/WTO, Technical Barriers to Trade (TBT) has gradually replaced tariff and general non-tariff Barriers to Trade and become an... With the cutoff and limitation of tariff and traditional non-tariff Barriers to Trade by GATT/WTO, Technical Barriers to Trade (TBT) has gradually replaced tariff and general non-tariff Barriers to Trade and become an important measurement in new trade protectionism. This article analyzes the replacement of TBT on tariff barrier for exporting countries, as well as the trading pattern of TBT in its maturing period through the discussion of macro strategies of surpassing TBT; meanwhile it also probes into the examination and supervision policies of governmental functional departments. 展开更多
关键词 TBT WTO GATT research on Replacing effects Examination System of TBT against Tariff Impediment to Textile and Apparel Trade
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Research on the effects of PIAS3 expression on the invasion of glioma TJ905 cells
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作者 潘天鸿 《外科研究与新技术》 2011年第3期204-205,共2页
Objective To investigate the function and possible mechanisms of PIAS3 expression on the invasion of TJ905 cells. Methods PIAS3 overexpression vectors were constructed and PIAS3 siRNA were chemically synthesized, whic... Objective To investigate the function and possible mechanisms of PIAS3 expression on the invasion of TJ905 cells. Methods PIAS3 overexpression vectors were constructed and PIAS3 siRNA were chemically synthesized, which were separately transfected into TJ905 cells for upregulation or 展开更多
关键词 PIAS research on the effects of PIAS3 expression on the invasion of glioma TJ905 cells
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小檗碱抗结直肠癌药理作用研究进展
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作者 王国娟 晏玉薇 +4 位作者 朱柰澄 陈秀丹 李南欣 钟晨 余文燕 《辽宁中医杂志》 北大核心 2026年第1期211-216,I0008,共7页
结直肠癌是常见的消化道恶性肿瘤,目前结直肠癌的治疗早期以手术为主,中晚期以放疗、化疗为主。长期临床实践证明,中医药对于癌症的治疗及预防具有显著效果。湿热内蕴是结直肠癌早期主要病机,黄连具有苦寒清热效果,常用于治疗湿热型肠... 结直肠癌是常见的消化道恶性肿瘤,目前结直肠癌的治疗早期以手术为主,中晚期以放疗、化疗为主。长期临床实践证明,中医药对于癌症的治疗及预防具有显著效果。湿热内蕴是结直肠癌早期主要病机,黄连具有苦寒清热效果,常用于治疗湿热型肠道疾病。小檗碱是中药黄连有效单体之一,在结直肠癌进展中具有治疗作用。该文旨在从小檗碱抑制结直肠癌细胞的增殖、促进凋亡、抑制侵袭转移、抗炎、调节肠道菌群、促进自噬、与其他药物协同抗癌等方面,全面分析探讨小檗碱抗结直肠癌机制的药理作用及其相关机制研究,以期为小檗碱治疗结直肠癌应用于临床以及新药研发提供新思路。 展开更多
关键词 小檗碱 结直肠癌 药理作用 研究进展
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参蛤补肺汤联合化疗治疗利福平敏感复治肺结核临床观察
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作者 陈代平 方明珠 +2 位作者 程瑶 赵丽华 李林 《辽宁中医杂志》 北大核心 2026年第1期91-95,共5页
目的探究参蛤补肺汤联合西药化疗治疗利福平敏感复治肺结核的临床效果。方法将136例利福平敏感型复治肺结核患者随机分成两组,包括治疗组(68例)和对照组(68例),其中治疗组采用标准化的治疗方案:(2HRZS(L)E/6HRE)联合参蛤补肺汤;对照组... 目的探究参蛤补肺汤联合西药化疗治疗利福平敏感复治肺结核的临床效果。方法将136例利福平敏感型复治肺结核患者随机分成两组,包括治疗组(68例)和对照组(68例),其中治疗组采用标准化的治疗方案:(2HRZS(L)E/6HRE)联合参蛤补肺汤;对照组则单用标准化的治疗方案。观察两组在治疗后2、5个月和疗程结束时的痰菌转阴、病灶吸收及空洞闭合情况,计算两组的治疗成功率;观察两组在治疗后的临床症状及免疫功能改善情况;通过多因素回归分析治疗成功的相关因素。结果治疗组在各个观察点的细菌转阴率均高于对照组(P<0.05),治疗组的治疗成功率为88.2%(60/68),高于对照组的72.1%(49/68)(P<0.05);在疗程结束后,治疗组的胸部X线病灶吸收显效率高于对照组(P<0.05),临床症状改善快于对照组(P<0.05),T淋巴细胞CD_(4)^(+)/CD_(8)^(+)比值高于对照组(P<0.05);治疗过程中,治疗组不良反应发生率低于对照组(P<0.05);治疗前患者为多耐药是治疗成功的独立危险因素,而使用参蛤补肺汤辅助治疗则是治疗成功的独立保护因素。结论使用参蛤补肺汤辅助治疗利福平敏感的复治肺结核患者,可促进细菌转阴、提高治疗成功率、加速病灶吸收、促进症状改善、改善细胞免疫、减少不良反应,是更为优化的复治肺结核治疗方案。 展开更多
关键词 复治肺结核 参蛤补肺汤 利福平敏感 方案评价 疗效比较研究
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果粮间作系统小气候效应研究进展
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作者 杨姝 杜桂娟 +3 位作者 赵凤艳 向午燕 张诗雨 蔡倩 《农业科技与装备》 2026年第1期52-54,共3页
果粮间作系统对改善生态环境和促进农业可持续发展具有重要意义。在综述前人研究的基础上,简要阐述果粮间作系统的概念与内涵,概括并归纳国内外果粮间作系统小气候效应的主要研究内容及研究进展,重点分析风速、光照、温湿度、土壤水分... 果粮间作系统对改善生态环境和促进农业可持续发展具有重要意义。在综述前人研究的基础上,简要阐述果粮间作系统的概念与内涵,概括并归纳国内外果粮间作系统小气候效应的主要研究内容及研究进展,重点分析风速、光照、温湿度、土壤水分及土壤养分等方面的研究成果,以期为今后进一步优化果粮间作系统、提高农业经济水平和生态效益提供理论依据和技术支撑。 展开更多
关键词 果粮间作系统 小气候效应 研究进展
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中药药对治疗肺纤维化药理作用的研究进展
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作者 王珊珊 闫瑢玓 《天津中医药》 2026年第3期396-400,共5页
肺纤维化是一种进行性、破坏性和致命性的间质性肺疾病。随着肺纤维化全球疾病负担的日益加重,患者的生存质量和生命健康受到严重影响。研究发现,中医药辨证施治对肺纤维化具有独特优势,中药药对既可作为复方制剂的组合,亦可独立构成精... 肺纤维化是一种进行性、破坏性和致命性的间质性肺疾病。随着肺纤维化全球疾病负担的日益加重,患者的生存质量和生命健康受到严重影响。研究发现,中医药辨证施治对肺纤维化具有独特优势,中药药对既可作为复方制剂的组合,亦可独立构成精简方剂,在临床应用中具有高度灵活性。基于中国知网文献检索,筛选出39篇相关研究,归纳出养阴润燥、补肺益气、补肺益肾、活血化瘀4类共10组中药药对及研究进展,为肺纤维化的中医药防治提供临床参考。 展开更多
关键词 肺纤维化 中药药对 药理作用 研究进展
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甘草减轻黄药子致小鼠肝毒性机制研究
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作者 黄智锋 华碧春 +4 位作者 周奕 陈雪梅 陈水钫 郑乾文 黄铮 《山西中医》 2026年第2期69-72,共4页
目的:通过microRNA测序,从基因测序水平探究甘草配伍黄药子减轻肝毒性的实验机理。方法:将实验用小鼠随机分为黄药子组、配伍组、空白对照组,每组各10只,分别连续灌胃14天后,HE染色进行肝组织形态观察,同时采用转录组学技术测序肝组织mi... 目的:通过microRNA测序,从基因测序水平探究甘草配伍黄药子减轻肝毒性的实验机理。方法:将实验用小鼠随机分为黄药子组、配伍组、空白对照组,每组各10只,分别连续灌胃14天后,HE染色进行肝组织形态观察,同时采用转录组学技术测序肝组织microRNA基因表达谱,应用软件分析表达谱提示存在差异表达的基因。结果:共筛选出具有差异表达的microRNA共93个,其中黄药子组有57个microRNA显著下调,显著上调的有36个。结论:甘草可能通过膜电位调节、突触后特化结构、离子信号活性等生物功能;以及轴突导向和Ras信号通路、细胞信号转导通路(MAPK)等多通路调节降低黄药子毒性导致肝损伤。 展开更多
关键词 黄药子 肝毒性 甘草 减毒作用 MICRORNA 实验研究
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核桃壳化学成分、药理作用与药用价值的研究进展
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作者 孙宇靖 王彦钧 +3 位作者 边甜甜 张育贵 李咸慰 李越峰 《华西药学杂志》 北大核心 2026年第1期117-123,共7页
核桃壳是核桃中产量最大的副产品,在中国有药用记载,但目前资源利用率低,造成了极大浪费。核桃壳中含有酚酸类、黄酮类、醌类、多糖等活性物质,以及多种氨基酸、维生素等营养物质,具有抗氧化、抗肿瘤、抑菌、降脂等功效。现梳理近年来... 核桃壳是核桃中产量最大的副产品,在中国有药用记载,但目前资源利用率低,造成了极大浪费。核桃壳中含有酚酸类、黄酮类、醌类、多糖等活性物质,以及多种氨基酸、维生素等营养物质,具有抗氧化、抗肿瘤、抑菌、降脂等功效。现梳理近年来核桃壳化学物质及药理作用的研究进展,讨论核桃壳资源药用价值的开发与利用,为提升核桃壳资源的价值提供了参考。 展开更多
关键词 核桃壳 化学成分 抗氧化 抗肿瘤 抑菌 降脂 研究进展 药用价值 开发利用
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龙胆炮制历史沿革及化学成分、药理作用研究
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作者 秦聪聪 张诗敏 李玉清 《中华中医药学刊》 北大核心 2026年第1期133-139,I0014,共8页
龙胆炮制历史悠久,先后出现净制、切制、炒制、姜制、酒制、甘草制等炮制方法,其炮制规格和方法随历史变迁发生简化,现姜制、甘草制已不再采用。龙胆化学成分主要有环烯醚萜类、黄酮类、三萜类、生物碱类、挥发油类、多糖类及部分微量元... 龙胆炮制历史悠久,先后出现净制、切制、炒制、姜制、酒制、甘草制等炮制方法,其炮制规格和方法随历史变迁发生简化,现姜制、甘草制已不再采用。龙胆化学成分主要有环烯醚萜类、黄酮类、三萜类、生物碱类、挥发油类、多糖类及部分微量元素,具有抗炎镇痛、抗肿瘤、神经保护、保肝、抗氧化、降糖、降脂等多种生物活性。龙胆炮制后会使环烯醚萜苷类结构发生脱羧、氧化、环合,挥发油类成分出现蒸发、氧化等,部分微量元素成分含量发生变化,进而改变其药性,增强药效。龙胆炒制后可使寒性减弱,酒制龙胆能增强保肝等药理活性。研究古今龙胆的炮制变化及其不同炮制品对化学成分和药理作用的影响,以期为中药材龙胆的规范化研究提供帮助。 展开更多
关键词 龙胆 炮制 化学成分 药理作用 研究进展
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灵芝多糖化学结构及药理作用研究进展
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作者 井晓婕 姜思亮 +1 位作者 夏永刚 梁军 《中医药学报》 2026年第2期120-128,共9页
灵芝是一种珍贵的药用真菌,在中医药和现代医学中均具有重要价值。中医认为灵芝具有补气安神、止咳平喘的功效。近年来,灵芝多糖作为灵芝的主要活性成分之一,因其表现出抗肿瘤、抗病毒、抗氧化、抗衰老等药理活性而备受关注。本文总结... 灵芝是一种珍贵的药用真菌,在中医药和现代医学中均具有重要价值。中医认为灵芝具有补气安神、止咳平喘的功效。近年来,灵芝多糖作为灵芝的主要活性成分之一,因其表现出抗肿瘤、抗病毒、抗氧化、抗衰老等药理活性而备受关注。本文总结了灵芝多糖的化学结构及药理作用的研究现状,以期为灵芝的进一步开发利用提供参考。 展开更多
关键词 灵芝多糖 化学结构 药理作用 研究进展
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滚轮微针联合氨甲环酸外用治疗黄褐斑临床观察
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作者 鲁亚青 荀珊 +3 位作者 杨莉 魏妍 许妍 李雪莉 《实用皮肤病学杂志》 2026年第1期41-45,共5页
目的观察滚轮微针联合氨甲环酸治疗黄褐斑的疗效与安全性。方法选择2024年6月至2024年7月河南省人民医院就诊的60例稳定期黄褐斑女性患者作为研究对象,采用随机数表法将其分为治疗组与对照组,每组30例。对照组予氨甲环酸精华液每日2次... 目的观察滚轮微针联合氨甲环酸治疗黄褐斑的疗效与安全性。方法选择2024年6月至2024年7月河南省人民医院就诊的60例稳定期黄褐斑女性患者作为研究对象,采用随机数表法将其分为治疗组与对照组,每组30例。对照组予氨甲环酸精华液每日2次外用治疗,治疗组在对照组基础上予滚轮微针治疗,并于术后24 h内外用含氨甲环酸的焕颜精萃液,每4周治疗1次,共3次。比较两组黄褐斑面积和严重程度评分(MASI)、皮肤色度指标(L^(*)、a^(*)、b^(*)值)、皮肤病生活质量指数(DLQI)及患者满意度,观察并记录两组患者治疗期间发生的不良反应。结果治疗结束后12周,两组MASI评分、a^(*)值、b^(*)值均降低(P<0.05),且治疗组均低于对照组(P<0.05),治疗组差值大于对照组(P<0.05)。治疗结束后12周,两组L^(*)值均升高(P<0.05),且治疗组高于对照组(P<0.05),治疗组差值大于对照组(P<0.05)。治疗结束后12周,两组DLQI评分均降低(P<0.05),且治疗组差值大于对照组(P<0.05)。治疗组满意度(86.67%)高于对照组(63.33%)(P<0.05)。治疗组治疗期间仅1例患者出现轻微疼痛,冷敷后缓解,无炎症后色素沉着或严重不良反应。结论滚轮微针联合氨甲环酸外用治疗黄褐斑效果显著,安全性良好。 展开更多
关键词 黄褐斑 氨甲环酸 微针疗法 疗效比较研究
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