Sensitivity analysis is one of the effective methods in the dynamic modification. The sensitivity of the modal parameters such as the natural frequencies and mode shapes in undamped free vibration of mechanical transm...Sensitivity analysis is one of the effective methods in the dynamic modification. The sensitivity of the modal parameters such as the natural frequencies and mode shapes in undamped free vibration of mechanical transmission system is analyzed in this paper.In particular,the sensitivities of the modal parameters to physical parameters of shaft system such as the inertia and stiffness are given.A calculation formula for dynamic modification is presented based on the analysis of modal parameter.With a mechanical transmission system as an example, the sensitivities of natural frequencies and modes shape are calculated and analyzed. Furthermore, the dynamic modification is also carried out and a good result is obtained.展开更多
A modification of central profile with trigonometric curve is proposed based on the theory of engagement of scroll compressor. General modification equations for central profile of a pair of scrolls are given and vari...A modification of central profile with trigonometric curve is proposed based on the theory of engagement of scroll compressor. General modification equations for central profile of a pair of scrolls are given and various modification patterns are discussed. The equidistant method is employed to calculate the volume of a sealed chamber and a set of general equations is represented. Modification parameters affecting geometric and dynamic property of a scroll compressor are analyzed systematically, and the relations between them are accurately determined. The condition for transforming a trigonometric curve modification into an arc-curve modification is explained. The conclusions can also be applied to other scroll fluid machines.展开更多
As fundamental components of life,biomacromolecules such as proteins,nucleic acids,and polysaccharides are constantly undergoing chemical modifications that are versatile,site-specific,and dynamic,and are often tightl...As fundamental components of life,biomacromolecules such as proteins,nucleic acids,and polysaccharides are constantly undergoing chemical modifications that are versatile,site-specific,and dynamic,and are often tightly regulated.This review summarizes recent advances in the study of dynamic modifications and chemical interventions of biomacromolecules that are supported by the major research plan(MRP)of the National Natural Science Foundation of China(NSFC).Firstly,we will introduce novel methods and techniques in chemical labeling,detection,as well as manipulation of dynamic biomacromolecular modifications.We will next discuss the molecular mechanisms and biological functions of the dynamic modifications of biomacromolecules,particularly of newly discovered modifications.Finally,we will explore chemical intervention strategies targeting these modifications and the associated disease.This review selectively highlights significant recent progress beingmade by the researchers supported byMRP,with a particular emphasis on representative chemical techniques and their biomedical applications along this exciting direction.展开更多
文摘Sensitivity analysis is one of the effective methods in the dynamic modification. The sensitivity of the modal parameters such as the natural frequencies and mode shapes in undamped free vibration of mechanical transmission system is analyzed in this paper.In particular,the sensitivities of the modal parameters to physical parameters of shaft system such as the inertia and stiffness are given.A calculation formula for dynamic modification is presented based on the analysis of modal parameter.With a mechanical transmission system as an example, the sensitivities of natural frequencies and modes shape are calculated and analyzed. Furthermore, the dynamic modification is also carried out and a good result is obtained.
基金This project is supported by Provincial Natural Science Foundation of Gansu(No.ZS032-B25-026).
文摘A modification of central profile with trigonometric curve is proposed based on the theory of engagement of scroll compressor. General modification equations for central profile of a pair of scrolls are given and various modification patterns are discussed. The equidistant method is employed to calculate the volume of a sealed chamber and a set of general equations is represented. Modification parameters affecting geometric and dynamic property of a scroll compressor are analyzed systematically, and the relations between them are accurately determined. The condition for transforming a trigonometric curve modification into an arc-curve modification is explained. The conclusions can also be applied to other scroll fluid machines.
文摘As fundamental components of life,biomacromolecules such as proteins,nucleic acids,and polysaccharides are constantly undergoing chemical modifications that are versatile,site-specific,and dynamic,and are often tightly regulated.This review summarizes recent advances in the study of dynamic modifications and chemical interventions of biomacromolecules that are supported by the major research plan(MRP)of the National Natural Science Foundation of China(NSFC).Firstly,we will introduce novel methods and techniques in chemical labeling,detection,as well as manipulation of dynamic biomacromolecular modifications.We will next discuss the molecular mechanisms and biological functions of the dynamic modifications of biomacromolecules,particularly of newly discovered modifications.Finally,we will explore chemical intervention strategies targeting these modifications and the associated disease.This review selectively highlights significant recent progress beingmade by the researchers supported byMRP,with a particular emphasis on representative chemical techniques and their biomedical applications along this exciting direction.
