The regulatory processes in developmental biology research are significantly influenced by long non-coding RNAs(lncRNAs).However,the dynamics of lncRNA expression during human tooth development remain poorly understoo...The regulatory processes in developmental biology research are significantly influenced by long non-coding RNAs(lncRNAs).However,the dynamics of lncRNA expression during human tooth development remain poorly understood.In this research,we examined the lncRNAs present in the dental epithelium(DE)and dental mesenchyme(DM)at the late bud,cap,and early bell stages of human fetal tooth development through bulk RNA sequencing.Developmental regulators co-expressed with neighboring lncRNAs were significantly enriched in odontogenesis.Specific lncRNAs expressed in the DE and DM,such as PANCR,MIR205HG,DLX6-AS1,and DNM3OS,were identified through a combination of bulk RNA sequencing and single-cell analysis.Further subcluster analysis revealed lncRNAs specifically expressed in important regions of the tooth germ,such as the inner enamel epithelium and coronal dental papilla(CDP).Functionally,we demonstrated that CDP-specific DLX6-AS1 enhanced odontoblastic differentiation in human tooth germ mesenchymal cells and dental pulp stem cells.These findings suggest that lncRNAs could serve as valuable cell markers for tooth development and potential therapeutic targets for tooth regeneration.展开更多
The World Telecommunication Development Conference 2025(WTDC-25)will be hosted by the Government of Azerbaijan in Baku on November 17-28,2025.World Telecommunication Development Conferences(WTDCs)are convened in the p...The World Telecommunication Development Conference 2025(WTDC-25)will be hosted by the Government of Azerbaijan in Baku on November 17-28,2025.World Telecommunication Development Conferences(WTDCs)are convened in the period between two Plenipotentiary Conferences to consider topics,projects and programmes relevant to telecommunication development.WTDCs set the strategies and objectives for the development of telecommunication/ICT,providing direction and guidance to the ITU Telecommunication Development Sector(ITU-D).展开更多
Developing deep fragmented soft coalbed methane(CBM)can significantly enhance domestic natural gas supplies,reduce reliance on imported energy,and bolster national energy security.This manuscript provides a comprehens...Developing deep fragmented soft coalbed methane(CBM)can significantly enhance domestic natural gas supplies,reduce reliance on imported energy,and bolster national energy security.This manuscript provides a comprehensive review of commonly employed coalbed methane extraction technologies.It then delves into several critical issues in the current stage of CBM exploration and development in China,including the compatibility of existing technologies with CBM reservoirs,the characteristics and occurrence states of CBM reservoirs,critical desorption pressure,and gas generation mechanisms.Our research indicates that current CBM exploration and development technologies in China have reached an internationally advanced level,yet the industry is facing unprecedented challenges.Despite progress in low-permeability,high-value coal seams,significant breakthroughs have not been achieved in exploring other types of coal seams.For different coal reservoirs,integrated extraction technologies have been developed,such as surface pre-depressurisation and segmented hydraulic fracturing of coal seam roof strata.Additionally,techniques like large-scale volume fracturing in horizontal wells have been established,significantly enhancing reservoir stimulation effects and coalbed methane recovery rates.However,all of these technologies are fundamentally based on permeation.These technologies lack direct methods aimed at enhancing the diffusion rate of CBM,thereby failing to fully reflect the unique characteristics of CBM.Current CBM exploration and development theories and technologies are not universally applicable to all coal seams.They do not adequately account for the predominantly adsorbed state of CBM,and the complex and variable gas generation mechanisms further constrain CBM development in China.Finally,continuous exploration of new deep CBM exploration technologies is necessary.Integrating more effective reservoir stimulation technologies is essential to enhance technical adaptability concerning CBM reservoir characteristics,gas occurrence states,and gas generation mechanisms,ultimately achieving efficient CBM development.We conclude that while China possesses a substantial foundation of deep fractured CBM resources,industry development is constrained and requires continuous exploration of new CBM exploration and development technologies to utilize these resources effectively.展开更多
Since arriving in Singapore in 1993,William Yang,a visiting professor at the National University of Singapore(NUS),has spent over three decades immersed in the city-state’s vibrant landscape.Throughout these 32 years...Since arriving in Singapore in 1993,William Yang,a visiting professor at the National University of Singapore(NUS),has spent over three decades immersed in the city-state’s vibrant landscape.Throughout these 32 years,he has not only witnessed but also actively contributed to the flourishing friendship and dynamic cooperation between China and Singapore.“I was deeply struck when I first arrived in Singapore,”recalled Yang.“This country was ahead of China in terms of material living standards,economic development,and international outlook.”He describes this period as a“journey of learning.”展开更多
On June 3,Scopus,a database owned by Elsevier,released CiteScore 2024 metrics for academic journal evaluation.Both the Chinese and English editions of Petroleum Exploration and Development achieved record highs in the...On June 3,Scopus,a database owned by Elsevier,released CiteScore 2024 metrics for academic journal evaluation.Both the Chinese and English editions of Petroleum Exploration and Development achieved record highs in the past year,ranking among the top in various categories.The CiteScore of the Chinese edition increased to 9.9 in 2024 from 8.4 in 2023,ranking 13th out of 330 journals in the Earth and Planetary Sciences:Geology category and 2lst out of 239 journals in the Earth and Planetary Sciences:Geotechnical Engineering and Engineering Geology category.展开更多
This study systematically reviews the development history and key technological breakthroughs of large gas fields in the Ordos Basin,and summarizes the development models of three gas reservoir types,low-permeability ...This study systematically reviews the development history and key technological breakthroughs of large gas fields in the Ordos Basin,and summarizes the development models of three gas reservoir types,low-permeability carbonate,low-permeability sandstone and tight sandstone,as well as the progress in deep coal-rock gas development.The current challenges and future development directions are also discussed.Mature development models have been formed for the three representative types of gas reservoirs in the Ordos Basin:(1)Low-permeability carbonate reservoir development model featuring groove fine-scale characterization and three-dimensional vertical succession between Upper and Lower Paleozoic formations.(2)Low-permeability sandstone reservoir development model emphasizing horizontal well pressure-depletion production and vertical well pressure-controlled production.(3)Tight sandstone gas reservoir development model focusing on single-well productivity enhancement and well placement optimization.In deep coal-rock gas development,significant progress has been achieved in reservoir evaluation,sweet spot prediction,and geosteering of horizontal wells.The three types of reservoirs have entered the mid-to-late stages of the development,when the main challenge lies in accurately characterizing residual gas,evaluating secondary gas-bearing layers,and developing precise potential-tapping strategies.In contrast,for the early-stage development of deep coal-rock gas,continuous technological upgrades and cost reduction are essential to achieving economically viable large-scale development.Four key directions of future research and technological breakthroughs are proposed:(1)Utilizing dual-porosity(fracture-matrix)modeling techniques in low-permeability carbonate reservoirs to delineate the volume and distribution of remaining gas in secondary pay zones,supporting well pattern optimization and production enhancement of existing wells.(2)Integrating well-log and seismic data to characterize reservoir spatial distribution of successive strata,enhancing drilling success rates in low-permeability sandstone reservoirs.(3)Utilizing the advantages of horizontal wells to penetrate effective reservoirs laterally,achieving meter-scale quantification of small-scale single sand bodies in tight gas reservoirs,and applying high-resolution 3D geological models to clarify the distribution of remaining gas and guide well placement optimization.(4)Further strengthening the evaluation of deep coal-rock gas in terms of resource potential,well type and pattern,reservoir stimulation,single-well performance,and economic viability.展开更多
As climate crisis intensifies,increasing attention has been drawn to the low-carbon transition of energy and the development of new energy sources.However,recently,new energy development worldwide has faced growing ob...As climate crisis intensifies,increasing attention has been drawn to the low-carbon transition of energy and the development of new energy sources.However,recently,new energy development worldwide has faced growing obstacles,casting a shadow over its prospects.China’s achievements in new energy development are leading globally and have significantly contributed to global climate governance.Despite challenges,the future prospects of new energy development in China will significantly influence the global landscape of energy development and climate governance.展开更多
Since its inception,the Belt and Road Initiative(BRI)has emerged as a global platform for international cooperation,with infrastructure connectivity at its core.Infrastructure,often referred to as the“lifeblood”of e...Since its inception,the Belt and Road Initiative(BRI)has emerged as a global platform for international cooperation,with infrastructure connectivity at its core.Infrastructure,often referred to as the“lifeblood”of economic and social development,plays a pivotal role in breaking bottlenecks,bridging regional gaps,and driving inclusive growth-particularly in developing regions where inadequate infrastructure has long hindered progress.展开更多
The study offers a conceptual framework illuminating sustainable rural development by a continuous cycling interplay among five interdependent systems,physical,social,economic,knowledge,and creative.The framework is a...The study offers a conceptual framework illuminating sustainable rural development by a continuous cycling interplay among five interdependent systems,physical,social,economic,knowledge,and creative.The framework is applied to analyze the livelihood transition in the economic system and conversion of traditional knowledge in the creative system for farm households engaged in large cardamom cultivation in Northern mountainous region in Vietnam.This study used a probit model to examine a data set comprising 300 households and confirmed that factors within the social and physical systems(such as labor,access to information,social networks,land use,and transportation infrastructure)determined livelihood transition to tourism employment within the economic system.In addition,the conversion of traditional knowledge in the creative system was found to be contingent upon non-farm employment and credit capital in the economic system,as well as traditional knowledge and knowledge exchange in the knowledge system.This study demonstrates how the sustainable development of rural agriculture can be achieved by converting traditional knowledge and transferring livelihood,contributing to attain Sustainable Development Goals 2(Zero Hunger)and SDG 12(Responsible Consumption and Production).展开更多
This article explores how Cangzhou Refining&Chemical is advancing the development of a community of shared future between the enterprise and its employees,amidst the deepening reforms and high-quality development ...This article explores how Cangzhou Refining&Chemical is advancing the development of a community of shared future between the enterprise and its employees,amidst the deepening reforms and high-quality development of state-owned enterprises and their“interaction”with new quality productive forces.By prioritizing employee care and support,the company enhances organizational efficiency,converting employee engagement into tangible productivity,and offers a practical model for other innovation initiatives.展开更多
Against the background of energy conservation and emission reduction,green construction and intelligent buildings have become an inevitable trend in the transformation of the construction industry.They effectively red...Against the background of energy conservation and emission reduction,green construction and intelligent buildings have become an inevitable trend in the transformation of the construction industry.They effectively reduce environmental damage and pollution caused by construction projects during the construction process,improve the comfort and health of buildings,and are conducive to promoting the sustainable development of China’s construction industry.This paper analyzes the relationship between green construction and intelligent buildings,examines the dilemmas faced by the integrated development of green construction and intelligent buildings,and proposes measures such as optimizing architectural design schemes,advancing technological innovation,improving energy utilization efficiency,actively applying BIM technology,and strengthening building lifecycle management,so as to promote the sustainable development of China’s construction industry.展开更多
Global climate change has created substantial difficulties in the areas of sustainability,development,and environmental conservation due to the widespread dependence on fossil fuels for energy production.Nevertheless,...Global climate change has created substantial difficulties in the areas of sustainability,development,and environmental conservation due to the widespread dependence on fossil fuels for energy production.Nevertheless,the promotion of renewable energy programs has the potential to significantly expedite endeavors aimed at tackling climate change.Thus,it is essential to conduct a thorough analysis that considers the financial aspects to fully understand the main hurdles that are preventing the advancement of renewable energy initiatives.Italy is a leading country in the worldwide deployment of renewable energy.The objective of this research is to assess the impact of financial growth,economic progress,and energy expenses on Italy’s adoption of renewable energy sources.By employing the Auto-Regressive Distributed Lag(ARDL)technique,we analyzed annual data spanning from1990 to 2022.Findings revealed that a 1%increase in financial and economic development would boost renewable energy consumption in the long run by 0.29%and 0.48%,respectively.Instead,a 1%increase in energy prices might reduce consumption of renewable energy by 0.05%in the long run.This study’s primary significance lies in furnishing actionable strategies for Italy to augment green finance for renewable energy,fostering sustained social and economic progress.Moreover,the analytical insights gleaned from this research offer valuable insights for energy-importing nations worldwide.展开更多
BACKGROUND Unintended pregnancy occurs when an individual or couple conceives without planning or desire,which can potentially affect a child’s physical,mental,and social well-being.This can then lead to long-term so...BACKGROUND Unintended pregnancy occurs when an individual or couple conceives without planning or desire,which can potentially affect a child’s physical,mental,and social well-being.This can then lead to long-term socioeconomic challenges for families and communities.Although its impact on child growth and development is a pressing concern,research remains limited particularly in multicenter settings.AIM To examine the long-term consequences of unintended pregnancy on the critical years of early childhood growth and development.METHODS This analytical observational study employed a case-control design and was conducted in research centers across Indonesia,encompassing those located in Central Java,Lampung,Bali,and West Nusa Tenggara.A total of 700 children aged≤5 years with histories of intended or unintended pregnancies participated.Data collection involved structured interviews and direct anthropometric and developmental assessments.Data analyses were conducted using multivariate statistics and partial least squares structural equation modeling.RESULTS Unintended pregnancy was found to have a statistically significant effect on both child growth(t=8.178;P<0.001)and child development(t=25.688;P<0.001).Key growth problems identified included underweight,undernutrition,abnormal head circumference,and stunting.Developmental challenges prominently associated with unintended pregnancy included behavioral and emotional disorders,autism spectrum disorder,attentiondeficit/hyperactivity disorder,social and motor skill deficits,as well as visual and hearing impairments.CONCLUSION Unintended pregnancy significantly affects child growth and development,underscoring the need for early intervention,quality prenatal care,and strengthened family planning policies.展开更多
Taking its advantages as a state-owned financial institution,the Bank of China Shanghai Branch has formulated the action plan for the high-quality development of AI,which includes ten aspects.First,it will invest no l...Taking its advantages as a state-owned financial institution,the Bank of China Shanghai Branch has formulated the action plan for the high-quality development of AI,which includes ten aspects.First,it will invest no less than 100 billion yuan in the next five years to provide strong comprehensive financial support for various entities in Shanghai’s entire AI industry chain.展开更多
Dongyuemiao Member shale in the Sichuan Basin,China,is characterized by organic-rich shale intervals with different types of interbeds and accumulation modes.The aim of this study is to elucidate the impact of paleoen...Dongyuemiao Member shale in the Sichuan Basin,China,is characterized by organic-rich shale intervals with different types of interbeds and accumulation modes.The aim of this study is to elucidate the impact of paleoenvironmental indicators on interbed development.With this aim in mind,we established an interbed classification scheme and quantified the development of different types of interbeds and their frequencies.We categorized the shale interbeds into three types based on interbed type:silt interbeds(SIs),shell fragment interbeds(SFIs),and shell skeleton interbeds(SSIs).The SIs,SFIs,and SSIs are respectively the products of extrabasinal low-density turbidity currents,intrabasinal debris flow,and intrabasinal low-density turbidity currents.We propose that variations in paleoenvironmental conditions primarily influenced the types of interbeds that developed but had minimal impact on the frequency of their development.Models depicting the interbed development within the 1st Submember of Dongyuemiao Member indicate that during the early Dongyuemiao depositional period,under conditions of relatively aridity,weak weathering,high terrigenous input,and strong hydrodynamic activity,SSIs were well developed.In the middle depositional period,as the climate gradually transitioned to more humid conditions,and the weathering intensity and amount of terrestrial input increased,the development of SIs and SFIs significantly increased.During the late depositional period,with a continuous decrease in terrestrial inputs and sedimentation rates,the development of SIs decreased while that of SSIs increased.展开更多
In today’s rapidly evolving digital landscape,web application security has become paramount as organizations face increasingly sophisticated cyber threats.This work presents a comprehensive methodology for implementi...In today’s rapidly evolving digital landscape,web application security has become paramount as organizations face increasingly sophisticated cyber threats.This work presents a comprehensive methodology for implementing robust security measures in modern web applications and the proof of the Methodology applied to Vue.js,Spring Boot,and MySQL architecture.The proposed approach addresses critical security challenges through a multi-layered framework that encompasses essential security dimensions including multi-factor authentication,fine-grained authorization controls,sophisticated session management,data confidentiality and integrity protection,secure logging mechanisms,comprehensive error handling,high availability strategies,advanced input validation,and security headers implementation.Significant contributions are made to the field of web application security.First,a detailed catalogue of security requirements specifically tailored to protect web applications against contemporary threats,backed by rigorous analysis and industry best practices.Second,the methodology is validated through a carefully designed proof-of-concept implementation in a controlled environment,demonstrating the practical effectiveness of the security measures.The validation process employs cutting-edge static and dynamic analysis tools for comprehensive dependency validation and vulnerability detection,ensuring robust security coverage.The validation results confirm the prevention and avoidance of security vulnerabilities of the methodology.A key innovation of this work is the seamless integration of DevSecOps practices throughout the secure Software Development Life Cycle(SSDLC),creating a security-first mindset from initial design to deployment.By combining proactive secure coding practices with defensive security approaches,a framework is established that not only strengthens application security but also fosters a culture of security awareness within development teams.This hybrid approach ensures that security considerations are woven into every aspect of the development process,rather than being treated as an afterthought.展开更多
In the global wave of energy transition and low-carbon development,China Petroleum Enterprise Association,together with the University of International Business and Economics,China University of Petroleum-Beijing,Sout...In the global wave of energy transition and low-carbon development,China Petroleum Enterprise Association,together with the University of International Business and Economics,China University of Petroleum-Beijing,Southwest Petroleum University,and other institutions,released four significant blue books on April 17:Annual Operating Report of China’s Natural Gas Industry Blue Book(2024-2025),China Oil&Gas Industry Development Analysis and Outlook Blue Book(2024-2025),China Low-Carbon Economy Development Report Blue Book(2024-2025),and Refined Oil and New Energy Development Report Blue Book(2024-2025).This series of blue books provides a comprehensive and high-level analysis of the development,issues,and trends in the oil and gas industry,offering a detailed depiction of the China Oil&Gas industry and its progress towards low-carbon development.展开更多
China has achieved the poverty reduction goal of the United Nations 2030 Agenda for Sustainable Development 10 years ahead of schedule,contributing significantly to global poverty reduction.Despite extended efforts in...China has achieved the poverty reduction goal of the United Nations 2030 Agenda for Sustainable Development 10 years ahead of schedule,contributing significantly to global poverty reduction.Despite extended efforts in poverty elimination,there is a lack of quantitative studies categorizing and comparing poverty-elimination counties(PECs)based on their processes.This study proposes an innovative framework for analyzing PECs’development paths from the perspective of population-land-industry(PLI).We quantify the PLI matching degree of PECs in China during the critical phase of the battle against poverty through a multivariate matching model,classify PECs via K-means clustering according to the consistency in PLI matching degree evolution,and summarize the typical development patterns of PECs.Results indicate that the PLI matching degree of PECs in China increased substantially from 2015 to 2020,particularly in eastern areas,while the western region,including the Qinghai-Xizang Plateau and southwestern Xinjiang,shows untapped potential for improvement.Five types of PECs are identified,with the majority(30.1%)showing sustained moderate PLI matching and a minority(9.6%)experiencing long-term PLI mismatch.Industry is the shortfall of various PECs,and effective strategies to facilitate all types of PECs include the development of emerging businesses and the expansion of secondary and tertiary industries.Additionally,enriching rural labor force and increasing farmland use efficiency are essential for optimal PLI matching and positive interaction,ultimately ensuring poverty elimination and sustainable development.展开更多
The ecdysone-induced transcription factor E93 in model insects plays multiple roles in the insect metamorphosis processes,such as remodeling larval tissues and determining adult tissue formation.The knockdown of E93in...The ecdysone-induced transcription factor E93 in model insects plays multiple roles in the insect metamorphosis processes,such as remodeling larval tissues and determining adult tissue formation.The knockdown of E93in insects leads to incomplete metamorphosis,suggesting that E93 is a potential target for pest control.In this study,the HaE93 gene in the cotton bollworm Helicoverpa armigera,a polyphagous pest of various commercial crops worldwide,was identified and found to have high expression in the egg,prepupal,and pupal stages.The injection of ds HaE93 induced about 60%mortality in H.armigera at the larval-pupal stage.About 30%survived but showed delayed pupation and abnormal wings,and the females developed reduced ovaries.Therefore,about 90%of the HaE93 knockdown individuals failed to reproduce before they died.The results of qRT-PCR showed that the expression levels of ecdysone primary-response genes,chitin synthesis-related genes,and wing and ovary development-related genes were reduced in HaE93 knockdown H.armigera.These results indicated that HaE93plays a critical role in larva-pupa-adult metamorphosis and the development of the cuticle,wing,and ovary in female H.armigera by regulating the expression of the associated genes.Bioassays of ds HaE93 administered by either oral delivery or injection showed similar knockdown results,which suggested that HaE93 can be used as a target gene for the RNAi control of the pest H.armigera.展开更多
Background There have been numerous intervention studies focusing on the development of preterm infants,but there has been limited investigation into the home environment as a determinant of developmental outcomes in ...Background There have been numerous intervention studies focusing on the development of preterm infants,but there has been limited investigation into the home environment as a determinant of developmental outcomes in preterm infants.The aspects and extent to which the home environment affects the early(18 months corrected age)neuropsychological development of preterm infants are still unclear.Aims This study aimed to analyse the effect of the home environment on the neuropsychiatric development of preterm infants at 18 months corrected age after discharge from the neonatal intensive care unit(NICU).It also sought to provide a basis for promoting neuropsychiatric development among preterm infants by improving the home environment.Methods In this retrospective cross-sectional study,275 preterm infants born between January 2019 and January 2022 were followed up for systematic management after discharge from the NICU at Shanghai Children's Hospital.The Home Nurture Environment Questionnaire was used to assess the home environment of the infants and analyse its impact on the developmental quotient(evaluated by the Gesell Developmental Scale)and the rate of developmental delays at 18 months corrected age.Results A total of 41.454%of the infants were extremely preterm.The developmental quotient scores at 18 months corrected age were in the middle of the scale.The language domain had the highest rate of developmental delay(46.182%),followed by the adaptive domain(37.091%).Multiple logistic regression analyses showed that compared with infants in supportive home environments,infants with moderate/unsupportive home environments had significantly elevated risks of development delay:2.162-fold for global(odds ratio(OR)2.162,95% confidence interval(Cl)1.274 to 3.665,p=0.004),2.193-fold for fine motor(OR 2.193,95%CI 1.161 to 4.140,p=0.016),2.249-fold for language(0R 2.249,95%CI 1.336 to 3.786,p=0.002)and 2.042-fold for personal-social(OR 2.042,95%CI 1.149 to 3.628,p=0.015).Conclusions A supportive home environment is a crucial protective factor for the neuropsychological development of preterm infants.It is associated with higher developmental quotient scores and protects against neuropsychiatric delays.Incorporating evaluation and continuous improvement of the home environment into the management framework for preterm infants to promote optimal neurodevelopment is essential.展开更多
基金supported by the National Key Research and Development Program(2022YFA1104401)Beijing Municipal Government grant(Beijing Laboratory of Oral Health,PXM2021-014226-000041)+3 种基金Beijing Municipal Govemment(Beijing Scholar Program,PXM2021-014226-000020)National Natural Science Foundation of China(82030031,92149301,81991504,L2224038,82270945)Innovation Research Team Project of Beijing Stomatological Hospital,Capital Medical University(CXTD202201)Chinese Research Unit of Tooth Development and Regeneration,Academy of Medical Sciences(2019-12M-5-031).
文摘The regulatory processes in developmental biology research are significantly influenced by long non-coding RNAs(lncRNAs).However,the dynamics of lncRNA expression during human tooth development remain poorly understood.In this research,we examined the lncRNAs present in the dental epithelium(DE)and dental mesenchyme(DM)at the late bud,cap,and early bell stages of human fetal tooth development through bulk RNA sequencing.Developmental regulators co-expressed with neighboring lncRNAs were significantly enriched in odontogenesis.Specific lncRNAs expressed in the DE and DM,such as PANCR,MIR205HG,DLX6-AS1,and DNM3OS,were identified through a combination of bulk RNA sequencing and single-cell analysis.Further subcluster analysis revealed lncRNAs specifically expressed in important regions of the tooth germ,such as the inner enamel epithelium and coronal dental papilla(CDP).Functionally,we demonstrated that CDP-specific DLX6-AS1 enhanced odontoblastic differentiation in human tooth germ mesenchymal cells and dental pulp stem cells.These findings suggest that lncRNAs could serve as valuable cell markers for tooth development and potential therapeutic targets for tooth regeneration.
文摘The World Telecommunication Development Conference 2025(WTDC-25)will be hosted by the Government of Azerbaijan in Baku on November 17-28,2025.World Telecommunication Development Conferences(WTDCs)are convened in the period between two Plenipotentiary Conferences to consider topics,projects and programmes relevant to telecommunication development.WTDCs set the strategies and objectives for the development of telecommunication/ICT,providing direction and guidance to the ITU Telecommunication Development Sector(ITU-D).
基金supported by the National Natural Science Foundation of China(52074045,52274074)the Science Fund for Distinguished Young Scholars of Chongqing(CSTB2022NSCQ-JQX0028).
文摘Developing deep fragmented soft coalbed methane(CBM)can significantly enhance domestic natural gas supplies,reduce reliance on imported energy,and bolster national energy security.This manuscript provides a comprehensive review of commonly employed coalbed methane extraction technologies.It then delves into several critical issues in the current stage of CBM exploration and development in China,including the compatibility of existing technologies with CBM reservoirs,the characteristics and occurrence states of CBM reservoirs,critical desorption pressure,and gas generation mechanisms.Our research indicates that current CBM exploration and development technologies in China have reached an internationally advanced level,yet the industry is facing unprecedented challenges.Despite progress in low-permeability,high-value coal seams,significant breakthroughs have not been achieved in exploring other types of coal seams.For different coal reservoirs,integrated extraction technologies have been developed,such as surface pre-depressurisation and segmented hydraulic fracturing of coal seam roof strata.Additionally,techniques like large-scale volume fracturing in horizontal wells have been established,significantly enhancing reservoir stimulation effects and coalbed methane recovery rates.However,all of these technologies are fundamentally based on permeation.These technologies lack direct methods aimed at enhancing the diffusion rate of CBM,thereby failing to fully reflect the unique characteristics of CBM.Current CBM exploration and development theories and technologies are not universally applicable to all coal seams.They do not adequately account for the predominantly adsorbed state of CBM,and the complex and variable gas generation mechanisms further constrain CBM development in China.Finally,continuous exploration of new deep CBM exploration technologies is necessary.Integrating more effective reservoir stimulation technologies is essential to enhance technical adaptability concerning CBM reservoir characteristics,gas occurrence states,and gas generation mechanisms,ultimately achieving efficient CBM development.We conclude that while China possesses a substantial foundation of deep fractured CBM resources,industry development is constrained and requires continuous exploration of new CBM exploration and development technologies to utilize these resources effectively.
文摘Since arriving in Singapore in 1993,William Yang,a visiting professor at the National University of Singapore(NUS),has spent over three decades immersed in the city-state’s vibrant landscape.Throughout these 32 years,he has not only witnessed but also actively contributed to the flourishing friendship and dynamic cooperation between China and Singapore.“I was deeply struck when I first arrived in Singapore,”recalled Yang.“This country was ahead of China in terms of material living standards,economic development,and international outlook.”He describes this period as a“journey of learning.”
文摘On June 3,Scopus,a database owned by Elsevier,released CiteScore 2024 metrics for academic journal evaluation.Both the Chinese and English editions of Petroleum Exploration and Development achieved record highs in the past year,ranking among the top in various categories.The CiteScore of the Chinese edition increased to 9.9 in 2024 from 8.4 in 2023,ranking 13th out of 330 journals in the Earth and Planetary Sciences:Geology category and 2lst out of 239 journals in the Earth and Planetary Sciences:Geotechnical Engineering and Engineering Geology category.
文摘This study systematically reviews the development history and key technological breakthroughs of large gas fields in the Ordos Basin,and summarizes the development models of three gas reservoir types,low-permeability carbonate,low-permeability sandstone and tight sandstone,as well as the progress in deep coal-rock gas development.The current challenges and future development directions are also discussed.Mature development models have been formed for the three representative types of gas reservoirs in the Ordos Basin:(1)Low-permeability carbonate reservoir development model featuring groove fine-scale characterization and three-dimensional vertical succession between Upper and Lower Paleozoic formations.(2)Low-permeability sandstone reservoir development model emphasizing horizontal well pressure-depletion production and vertical well pressure-controlled production.(3)Tight sandstone gas reservoir development model focusing on single-well productivity enhancement and well placement optimization.In deep coal-rock gas development,significant progress has been achieved in reservoir evaluation,sweet spot prediction,and geosteering of horizontal wells.The three types of reservoirs have entered the mid-to-late stages of the development,when the main challenge lies in accurately characterizing residual gas,evaluating secondary gas-bearing layers,and developing precise potential-tapping strategies.In contrast,for the early-stage development of deep coal-rock gas,continuous technological upgrades and cost reduction are essential to achieving economically viable large-scale development.Four key directions of future research and technological breakthroughs are proposed:(1)Utilizing dual-porosity(fracture-matrix)modeling techniques in low-permeability carbonate reservoirs to delineate the volume and distribution of remaining gas in secondary pay zones,supporting well pattern optimization and production enhancement of existing wells.(2)Integrating well-log and seismic data to characterize reservoir spatial distribution of successive strata,enhancing drilling success rates in low-permeability sandstone reservoirs.(3)Utilizing the advantages of horizontal wells to penetrate effective reservoirs laterally,achieving meter-scale quantification of small-scale single sand bodies in tight gas reservoirs,and applying high-resolution 3D geological models to clarify the distribution of remaining gas and guide well placement optimization.(4)Further strengthening the evaluation of deep coal-rock gas in terms of resource potential,well type and pattern,reservoir stimulation,single-well performance,and economic viability.
文摘As climate crisis intensifies,increasing attention has been drawn to the low-carbon transition of energy and the development of new energy sources.However,recently,new energy development worldwide has faced growing obstacles,casting a shadow over its prospects.China’s achievements in new energy development are leading globally and have significantly contributed to global climate governance.Despite challenges,the future prospects of new energy development in China will significantly influence the global landscape of energy development and climate governance.
文摘Since its inception,the Belt and Road Initiative(BRI)has emerged as a global platform for international cooperation,with infrastructure connectivity at its core.Infrastructure,often referred to as the“lifeblood”of economic and social development,plays a pivotal role in breaking bottlenecks,bridging regional gaps,and driving inclusive growth-particularly in developing regions where inadequate infrastructure has long hindered progress.
文摘The study offers a conceptual framework illuminating sustainable rural development by a continuous cycling interplay among five interdependent systems,physical,social,economic,knowledge,and creative.The framework is applied to analyze the livelihood transition in the economic system and conversion of traditional knowledge in the creative system for farm households engaged in large cardamom cultivation in Northern mountainous region in Vietnam.This study used a probit model to examine a data set comprising 300 households and confirmed that factors within the social and physical systems(such as labor,access to information,social networks,land use,and transportation infrastructure)determined livelihood transition to tourism employment within the economic system.In addition,the conversion of traditional knowledge in the creative system was found to be contingent upon non-farm employment and credit capital in the economic system,as well as traditional knowledge and knowledge exchange in the knowledge system.This study demonstrates how the sustainable development of rural agriculture can be achieved by converting traditional knowledge and transferring livelihood,contributing to attain Sustainable Development Goals 2(Zero Hunger)and SDG 12(Responsible Consumption and Production).
文摘This article explores how Cangzhou Refining&Chemical is advancing the development of a community of shared future between the enterprise and its employees,amidst the deepening reforms and high-quality development of state-owned enterprises and their“interaction”with new quality productive forces.By prioritizing employee care and support,the company enhances organizational efficiency,converting employee engagement into tangible productivity,and offers a practical model for other innovation initiatives.
文摘Against the background of energy conservation and emission reduction,green construction and intelligent buildings have become an inevitable trend in the transformation of the construction industry.They effectively reduce environmental damage and pollution caused by construction projects during the construction process,improve the comfort and health of buildings,and are conducive to promoting the sustainable development of China’s construction industry.This paper analyzes the relationship between green construction and intelligent buildings,examines the dilemmas faced by the integrated development of green construction and intelligent buildings,and proposes measures such as optimizing architectural design schemes,advancing technological innovation,improving energy utilization efficiency,actively applying BIM technology,and strengthening building lifecycle management,so as to promote the sustainable development of China’s construction industry.
文摘Global climate change has created substantial difficulties in the areas of sustainability,development,and environmental conservation due to the widespread dependence on fossil fuels for energy production.Nevertheless,the promotion of renewable energy programs has the potential to significantly expedite endeavors aimed at tackling climate change.Thus,it is essential to conduct a thorough analysis that considers the financial aspects to fully understand the main hurdles that are preventing the advancement of renewable energy initiatives.Italy is a leading country in the worldwide deployment of renewable energy.The objective of this research is to assess the impact of financial growth,economic progress,and energy expenses on Italy’s adoption of renewable energy sources.By employing the Auto-Regressive Distributed Lag(ARDL)technique,we analyzed annual data spanning from1990 to 2022.Findings revealed that a 1%increase in financial and economic development would boost renewable energy consumption in the long run by 0.29%and 0.48%,respectively.Instead,a 1%increase in energy prices might reduce consumption of renewable energy by 0.05%in the long run.This study’s primary significance lies in furnishing actionable strategies for Italy to augment green finance for renewable energy,fostering sustained social and economic progress.Moreover,the analytical insights gleaned from this research offer valuable insights for energy-importing nations worldwide.
文摘BACKGROUND Unintended pregnancy occurs when an individual or couple conceives without planning or desire,which can potentially affect a child’s physical,mental,and social well-being.This can then lead to long-term socioeconomic challenges for families and communities.Although its impact on child growth and development is a pressing concern,research remains limited particularly in multicenter settings.AIM To examine the long-term consequences of unintended pregnancy on the critical years of early childhood growth and development.METHODS This analytical observational study employed a case-control design and was conducted in research centers across Indonesia,encompassing those located in Central Java,Lampung,Bali,and West Nusa Tenggara.A total of 700 children aged≤5 years with histories of intended or unintended pregnancies participated.Data collection involved structured interviews and direct anthropometric and developmental assessments.Data analyses were conducted using multivariate statistics and partial least squares structural equation modeling.RESULTS Unintended pregnancy was found to have a statistically significant effect on both child growth(t=8.178;P<0.001)and child development(t=25.688;P<0.001).Key growth problems identified included underweight,undernutrition,abnormal head circumference,and stunting.Developmental challenges prominently associated with unintended pregnancy included behavioral and emotional disorders,autism spectrum disorder,attentiondeficit/hyperactivity disorder,social and motor skill deficits,as well as visual and hearing impairments.CONCLUSION Unintended pregnancy significantly affects child growth and development,underscoring the need for early intervention,quality prenatal care,and strengthened family planning policies.
文摘Taking its advantages as a state-owned financial institution,the Bank of China Shanghai Branch has formulated the action plan for the high-quality development of AI,which includes ten aspects.First,it will invest no less than 100 billion yuan in the next five years to provide strong comprehensive financial support for various entities in Shanghai’s entire AI industry chain.
基金sponsored by the National Natural Science Foundation of China,China(No.42272171)National Science and Technology Major Project of China,China(No.2017ZX05036).
文摘Dongyuemiao Member shale in the Sichuan Basin,China,is characterized by organic-rich shale intervals with different types of interbeds and accumulation modes.The aim of this study is to elucidate the impact of paleoenvironmental indicators on interbed development.With this aim in mind,we established an interbed classification scheme and quantified the development of different types of interbeds and their frequencies.We categorized the shale interbeds into three types based on interbed type:silt interbeds(SIs),shell fragment interbeds(SFIs),and shell skeleton interbeds(SSIs).The SIs,SFIs,and SSIs are respectively the products of extrabasinal low-density turbidity currents,intrabasinal debris flow,and intrabasinal low-density turbidity currents.We propose that variations in paleoenvironmental conditions primarily influenced the types of interbeds that developed but had minimal impact on the frequency of their development.Models depicting the interbed development within the 1st Submember of Dongyuemiao Member indicate that during the early Dongyuemiao depositional period,under conditions of relatively aridity,weak weathering,high terrigenous input,and strong hydrodynamic activity,SSIs were well developed.In the middle depositional period,as the climate gradually transitioned to more humid conditions,and the weathering intensity and amount of terrestrial input increased,the development of SIs and SFIs significantly increased.During the late depositional period,with a continuous decrease in terrestrial inputs and sedimentation rates,the development of SIs decreased while that of SSIs increased.
文摘In today’s rapidly evolving digital landscape,web application security has become paramount as organizations face increasingly sophisticated cyber threats.This work presents a comprehensive methodology for implementing robust security measures in modern web applications and the proof of the Methodology applied to Vue.js,Spring Boot,and MySQL architecture.The proposed approach addresses critical security challenges through a multi-layered framework that encompasses essential security dimensions including multi-factor authentication,fine-grained authorization controls,sophisticated session management,data confidentiality and integrity protection,secure logging mechanisms,comprehensive error handling,high availability strategies,advanced input validation,and security headers implementation.Significant contributions are made to the field of web application security.First,a detailed catalogue of security requirements specifically tailored to protect web applications against contemporary threats,backed by rigorous analysis and industry best practices.Second,the methodology is validated through a carefully designed proof-of-concept implementation in a controlled environment,demonstrating the practical effectiveness of the security measures.The validation process employs cutting-edge static and dynamic analysis tools for comprehensive dependency validation and vulnerability detection,ensuring robust security coverage.The validation results confirm the prevention and avoidance of security vulnerabilities of the methodology.A key innovation of this work is the seamless integration of DevSecOps practices throughout the secure Software Development Life Cycle(SSDLC),creating a security-first mindset from initial design to deployment.By combining proactive secure coding practices with defensive security approaches,a framework is established that not only strengthens application security but also fosters a culture of security awareness within development teams.This hybrid approach ensures that security considerations are woven into every aspect of the development process,rather than being treated as an afterthought.
文摘In the global wave of energy transition and low-carbon development,China Petroleum Enterprise Association,together with the University of International Business and Economics,China University of Petroleum-Beijing,Southwest Petroleum University,and other institutions,released four significant blue books on April 17:Annual Operating Report of China’s Natural Gas Industry Blue Book(2024-2025),China Oil&Gas Industry Development Analysis and Outlook Blue Book(2024-2025),China Low-Carbon Economy Development Report Blue Book(2024-2025),and Refined Oil and New Energy Development Report Blue Book(2024-2025).This series of blue books provides a comprehensive and high-level analysis of the development,issues,and trends in the oil and gas industry,offering a detailed depiction of the China Oil&Gas industry and its progress towards low-carbon development.
基金supported by the National Natural Science Foundation of China(Grants No.41931293,42271279,42293271,and 41801175).
文摘China has achieved the poverty reduction goal of the United Nations 2030 Agenda for Sustainable Development 10 years ahead of schedule,contributing significantly to global poverty reduction.Despite extended efforts in poverty elimination,there is a lack of quantitative studies categorizing and comparing poverty-elimination counties(PECs)based on their processes.This study proposes an innovative framework for analyzing PECs’development paths from the perspective of population-land-industry(PLI).We quantify the PLI matching degree of PECs in China during the critical phase of the battle against poverty through a multivariate matching model,classify PECs via K-means clustering according to the consistency in PLI matching degree evolution,and summarize the typical development patterns of PECs.Results indicate that the PLI matching degree of PECs in China increased substantially from 2015 to 2020,particularly in eastern areas,while the western region,including the Qinghai-Xizang Plateau and southwestern Xinjiang,shows untapped potential for improvement.Five types of PECs are identified,with the majority(30.1%)showing sustained moderate PLI matching and a minority(9.6%)experiencing long-term PLI mismatch.Industry is the shortfall of various PECs,and effective strategies to facilitate all types of PECs include the development of emerging businesses and the expansion of secondary and tertiary industries.Additionally,enriching rural labor force and increasing farmland use efficiency are essential for optimal PLI matching and positive interaction,ultimately ensuring poverty elimination and sustainable development.
基金supported by the National Natural Science Foundation of China(32001912 and 32370525)the Henan Provincial Natural Science Foundation,China(232300420012)。
文摘The ecdysone-induced transcription factor E93 in model insects plays multiple roles in the insect metamorphosis processes,such as remodeling larval tissues and determining adult tissue formation.The knockdown of E93in insects leads to incomplete metamorphosis,suggesting that E93 is a potential target for pest control.In this study,the HaE93 gene in the cotton bollworm Helicoverpa armigera,a polyphagous pest of various commercial crops worldwide,was identified and found to have high expression in the egg,prepupal,and pupal stages.The injection of ds HaE93 induced about 60%mortality in H.armigera at the larval-pupal stage.About 30%survived but showed delayed pupation and abnormal wings,and the females developed reduced ovaries.Therefore,about 90%of the HaE93 knockdown individuals failed to reproduce before they died.The results of qRT-PCR showed that the expression levels of ecdysone primary-response genes,chitin synthesis-related genes,and wing and ovary development-related genes were reduced in HaE93 knockdown H.armigera.These results indicated that HaE93plays a critical role in larva-pupa-adult metamorphosis and the development of the cuticle,wing,and ovary in female H.armigera by regulating the expression of the associated genes.Bioassays of ds HaE93 administered by either oral delivery or injection showed similar knockdown results,which suggested that HaE93 can be used as a target gene for the RNAi control of the pest H.armigera.
基金funded by Shanghai Municipal Health and Wellness Commission Health Industry Clinical Research Special Project(202140299).
文摘Background There have been numerous intervention studies focusing on the development of preterm infants,but there has been limited investigation into the home environment as a determinant of developmental outcomes in preterm infants.The aspects and extent to which the home environment affects the early(18 months corrected age)neuropsychological development of preterm infants are still unclear.Aims This study aimed to analyse the effect of the home environment on the neuropsychiatric development of preterm infants at 18 months corrected age after discharge from the neonatal intensive care unit(NICU).It also sought to provide a basis for promoting neuropsychiatric development among preterm infants by improving the home environment.Methods In this retrospective cross-sectional study,275 preterm infants born between January 2019 and January 2022 were followed up for systematic management after discharge from the NICU at Shanghai Children's Hospital.The Home Nurture Environment Questionnaire was used to assess the home environment of the infants and analyse its impact on the developmental quotient(evaluated by the Gesell Developmental Scale)and the rate of developmental delays at 18 months corrected age.Results A total of 41.454%of the infants were extremely preterm.The developmental quotient scores at 18 months corrected age were in the middle of the scale.The language domain had the highest rate of developmental delay(46.182%),followed by the adaptive domain(37.091%).Multiple logistic regression analyses showed that compared with infants in supportive home environments,infants with moderate/unsupportive home environments had significantly elevated risks of development delay:2.162-fold for global(odds ratio(OR)2.162,95% confidence interval(Cl)1.274 to 3.665,p=0.004),2.193-fold for fine motor(OR 2.193,95%CI 1.161 to 4.140,p=0.016),2.249-fold for language(0R 2.249,95%CI 1.336 to 3.786,p=0.002)and 2.042-fold for personal-social(OR 2.042,95%CI 1.149 to 3.628,p=0.015).Conclusions A supportive home environment is a crucial protective factor for the neuropsychological development of preterm infants.It is associated with higher developmental quotient scores and protects against neuropsychiatric delays.Incorporating evaluation and continuous improvement of the home environment into the management framework for preterm infants to promote optimal neurodevelopment is essential.
