期刊文献+
共找到1,007篇文章
< 1 2 51 >
每页显示 20 50 100
Information Diffusion Models and Fuzzing Algorithms for a Privacy-Aware Data Transmission Scheduling in 6G Heterogeneous ad hoc Networks
1
作者 Borja Bordel Sánchez Ramón Alcarria Tomás Robles 《Computer Modeling in Engineering & Sciences》 2026年第2期1214-1234,共21页
In this paper,we propose a new privacy-aware transmission scheduling algorithm for 6G ad hoc networks.This system enables end nodes to select the optimum time and scheme to transmit private data safely.In 6G dynamic h... In this paper,we propose a new privacy-aware transmission scheduling algorithm for 6G ad hoc networks.This system enables end nodes to select the optimum time and scheme to transmit private data safely.In 6G dynamic heterogeneous infrastructures,unstable links and non-uniform hardware capabilities create critical issues regarding security and privacy.Traditional protocols are often too computationally heavy to allow 6G services to achieve their expected Quality-of-Service(QoS).As the transport network is built of ad hoc nodes,there is no guarantee about their trustworthiness or behavior,and transversal functionalities are delegated to the extreme nodes.However,while security can be guaranteed in extreme-to-extreme solutions,privacy cannot,as all intermediate nodes still have to handle the data packets they are transporting.Besides,traditional schemes for private anonymous ad hoc communications are vulnerable against modern intelligent attacks based on learning models.The proposed scheme fulfills this gap.Findings show the probability of a successful intelligent attack reduces by up to 65%compared to ad hoc networks with no privacy protection strategy when used the proposed technology.While congestion probability can remain below 0.001%,as required in 6G services. 展开更多
关键词 6G networks ad hoc networks PRIVACY scheduling algorithms diffusion models fuzzing algorithms
在线阅读 下载PDF
托珠单抗通过抑制IL-6-JAK-STAT3信号逆转骨髓基质细胞介导的AML化疗耐药
2
作者 肖启荣 李晓静 +5 位作者 林碧寸 林凯婷 林晓斌 王匡非 李暐 陈萍 《中国药理学通报》 北大核心 2026年第1期49-55,共7页
目的研究托珠单抗(tocilizumab,TCZ)通过阻断IL-6/JAK/STAT3信号通路,逆转骨髓微环境介导的急性髓系白血病(acute myeloid leukemia,AML)细胞化疗耐药。方法建立AML细胞(U937、HL-60)与HS-5基质细胞的共培养体系,Western blot检测IL-6-J... 目的研究托珠单抗(tocilizumab,TCZ)通过阻断IL-6/JAK/STAT3信号通路,逆转骨髓微环境介导的急性髓系白血病(acute myeloid leukemia,AML)细胞化疗耐药。方法建立AML细胞(U937、HL-60)与HS-5基质细胞的共培养体系,Western blot检测IL-6-JAK-STAT3通路活化状态;利用IL-6敲除HS-5细胞及TCZ干预,结合CCK-8和AnnexinVAPC/7-AAD双染法分析AML细胞对阿糖胞苷(cytarabine,Ara-C)的敏感性变化;最后通过AML异种移植模型体内验证TCZ对Ara-C的协同抗白血病作用。结果在黏附共培养体系中,HS-5细胞高表达IL-6,AML细胞表现STAT3信号通路激活。通过基因敲低IL-6或使用TCZ干预,可有效抑制AML细胞中JAK2/STAT3的磷酸化激活。另外,体内外实验证实TCZ能够明显增强AML细胞对Ara-C化疗的敏感性。结论TCZ通过靶向抑制IL-6/JAK/STAT3信号通路,明显增强AML细胞对Ara-C的化学敏感性。 展开更多
关键词 急性髓细胞白血病 骨髓基质细胞 共培养模型 白细胞介素6 托珠单抗 化疗耐药
暂未订购
Temperature and Precipitation Change over South China in CMIP5 and CMIP6 Models:Historical Simulation and Future Projection
3
作者 Dongdong PENG Tianjun ZHOU +3 位作者 Sheng HU Lixia ZHANG Jiayu ZHENG Jingxuan QU 《Advances in Atmospheric Sciences》 2025年第7期1423-1441,共19页
Revealing regional climate changes is vital for policymaking activities related to climate change adaptation and mitigation.South China is a well-developed region with a dense population,but the level of uncertainty i... Revealing regional climate changes is vital for policymaking activities related to climate change adaptation and mitigation.South China is a well-developed region with a dense population,but the level of uncertainty in climate projections remains to be evaluated in detail.In this study,we comprehensively assessed the historical simulations and future projections of climate change in South China based on CMIP5/CMIP6 models.We show evidence that CMIP5/CMIP6 models can skillfully reproduce the observed distributions of annual/seasonal mean temperature but show much lower skill for precipitation.CMIP6 outperforms CMIP5 in the historical simulations,as evidenced by more models with lower bias magnitude and higher skill scores.During 2021–2100,the annual mean temperature over South China is projected to increase significantly at a rate of 0.53(0.42–0.63)and 0.59(0.52–0.66)℃(10 yr)^(-1),while precipitation is projected to increase slightly at a rate of 0.78(0.15–1.56)and 1.52(0.91–2.30)%(10 yr)^(-1),under the RCP8.5 and SSP5-8.5 scenarios,respectively.CMIP6 models project larger annual/seasonal mean temperature and precipitation trends than CMIP5 models under equivalent scenarios.The temperature in South China is projected to increase robustly by more than1.5℃during 2041–2060 under RCP4.5 and SSP2-4.5,but by 4.5℃during 2081–2100,under RCP8.5 and SSP5-8.5 with respect to 1850–1900.The uncertainty in temperature projections is mainly dominated by model uncertainty and scenario uncertainty,while internal uncertainty contributes some of the uncertainty during the near-term.The uncertainty in precipitation projection stems mainly from internal uncertainty and model uncertainty.For both the temperature and precipitation projection uncertainty,the relative sizes of contributions from the main contributors vary with time and show obvious seasonal differences. 展开更多
关键词 projection uncertainty model performance CMIP6 South China
在线阅读 下载PDF
Simulated Asymmetric Connection of SST in the Tasman Sea with Respect to the Opposite Phases of ENSO in Austral Summer in CMIP6 Models
4
作者 Hui CAI Xueqian SUN Shuanglin LI 《Advances in Atmospheric Sciences》 2025年第9期1833-1849,共17页
A prior observational study indicated an asymmetric link between sea surface temperature(SST)in the Tasman Sea and ENSO during austral summer.Specifically,El Niño is associated with a dipolar SST anomaly pattern,... A prior observational study indicated an asymmetric link between sea surface temperature(SST)in the Tasman Sea and ENSO during austral summer.Specifically,El Niño is associated with a dipolar SST anomaly pattern,featuring warming in the northwest and cooling in the southeast,whereas La Niña corresponds to basin-scale warming.This study employs the experiments of coupled models from the sixth phase of the Coupled Model Intercomparison Project(CMIP6)to assess ENSO’s impact on Tasman Sea SST.While all 15 models capture the observed dipolar SST anomalies(SSTAs)in the Tasman Sea during El Niño years,only 7 models capture the basin-scale warmth in the Tasman Sea during La Niña years.Consequently,the models are bifurcated into two groups:group-one models yield one physically reasonable asymmetric connection as observed,including the asymmetry of oceanic heat transport,especially the Ekman meridional transport anomalies induced by zonal wind stress driven by the asymmetric atmospheric circulation over the Tasman Sea.However,due to abnormal responses to ENSO and systematic biases in model simulations,including jet and storm tracks,oceanic heat fluxes,ocean currents,and SST,the group-two models fail to reproduce the asymmetric connection between the Tasman Sea and ENSO.This study not only validates the observational asymmetric connection of SSTAs in the Tasman Sea with respect to the two opposite ENSO phases,but also provides evidence and clues to reduce the bias in group-two models. 展开更多
关键词 asymmetric connection SST Tasman Sea ENSO CMIP6 model thermodynamics systematic bias
在线阅读 下载PDF
N_(6)-甲基腺苷相关长非编码RNA作为胃癌患者预后预测的潜在生物标志物
5
作者 徐思远 奚锦森 +2 位作者 杨逸 顾晓冬 项建斌 《上海医药》 2026年第1期13-25,53,共14页
RNA甲基化占整个RNA修饰的60%以上,而N_(6)-甲基腺苷(N_(6)-methyladenosine,m^(6)A)修饰是人类最常见的一种RNA修饰。m^(6)A修饰对基因表达的调节至关重要,其失调与多种疾病如肿瘤相关。我们以癌症基因组图谱(The Cancer Genome Atlas,... RNA甲基化占整个RNA修饰的60%以上,而N_(6)-甲基腺苷(N_(6)-methyladenosine,m^(6)A)修饰是人类最常见的一种RNA修饰。m^(6)A修饰对基因表达的调节至关重要,其失调与多种疾病如肿瘤相关。我们以癌症基因组图谱(The Cancer Genome Atlas,TCGA)胃癌数据集中的375例患者为对象,研究了m^(6)A相关长非编码RNA(long noncoding RNAs,lncRNAs)的预后意义:先进行Pearson相关性分析,以筛选m^(6)A相关lncRNAs,然后再进行单变量Cox回归分析,确定胃癌患者的预后。确定23种m^(6)A相关lncRNAs为预后lncRNAs后,运用LASSO-Cox回归方法,在TCGA胃癌数据集中构建m^(6)A相关lncRNAs(包括9种m^(6)A相关预后lncRNAs)预后模型。通过计算相关风险评分,并根据风险评分的中位值将胃癌患者分为低、高风险亚组。生存分析曲线和受试者操作特征曲线显示,此预后模型能对胃癌患者的预后进行可靠的预测。本研究揭示了m^(6)A RNA甲基化调节剂在胃癌发生发展中的重要性,并建立了一种m^(6)A基因表达分类模型,该模型可以令人满意地预测胃癌的预后。 展开更多
关键词 N_(6)-甲基腺苷 长非编码RNA 胃癌 预后模型 生物标志物
暂未订购
A study of ENSO magnitude and lifespan in CMIP6 models
6
作者 Siyu Ou De-Zheng Sun Ronghui Zhang 《Acta Oceanologica Sinica》 2025年第9期19-37,共19页
The magnitude of El Nino determines the level of its global impact.Yet,how well our state-of-the-art models simulate this key aspect of El Nino is not well documented.Previous studies tend to ignore El Nino-Southern O... The magnitude of El Nino determines the level of its global impact.Yet,how well our state-of-the-art models simulate this key aspect of El Nino is not well documented.Previous studies tend to ignore El Nino-Southern Oscillation(ENSO)asymmetry and equate the variance of ENSO to the magnitude of El Nino.Moreover,previous evaluations are more focused on the surface manifestation of El Nino.Here,we quantify the magnitudes of El Nino and La Nina separately,both at the surface and subsurface levels.At the surface,we find that while the magnitude of La Nina events in most models is generally stronger than observed,the magnitude of El Nino is more diverse to observations.In fact,in many models,El Nino is weaker than observed.This bias in the magnitude of El Nino is more pronounced in the subsurface.We attribute this weakness in the subsurface to the generally weaker coupling strength and the apparent stronger ENSO at the surface to a lack of sufficiently strong negative feedback from the surface heat flux in the models.When normalized by the variance of ENSO,the lack of exceptionally strong El Nino events in the models is more common and pronounced.We further studied the lifespan of El Nino and La Nina events and have found that multi-year duration is not confined to just La Nina events.There are also El Nino events that last more than one year.Moreover,we have found that multi-year long La Nina events tend to occur over the decades with strong El Nino events.The study also briefly explores the impact of global warming on the duration of ENSO events through the use of a simple model and simulations by CMIP6 models.It has been found that the frequency of multi-year El Nino and La Nina events increases with global warming. 展开更多
关键词 MAGNITUDE LIFESPAN El Nino and La Nina coupled models CMIP6
在线阅读 下载PDF
Westward shift of western North Pacific tropical cyclones in CMIP6-High Res MIP models
7
作者 Zhuoying Li Wen Zhou 《Atmospheric and Oceanic Science Letters》 2025年第2期86-93,共8页
Against the backdrop of climate change,the activity of tropical cyclones(TCs)has captured widespread attention.Observational datasets indicate a declining trend in the genesis longitude of western North Pacific(WNP)TC... Against the backdrop of climate change,the activity of tropical cyclones(TCs)has captured widespread attention.Observational datasets indicate a declining trend in the genesis longitude of western North Pacific(WNP)TCs.This study investigates the zonal changes of WNP TCs with CMIP6-HighResMIP models.These models capture the genesis density of WNP TCs fairly well.The results reveal a westward shift in TC genesis longitude.This trend is associated with the significant reduction in the TC frequency over the southeastern WNP.The study also discusses changes in large-scale circulation patterns and the impact of the strengthening Pacific Walker circulation. 展开更多
关键词 Tropical cyclones Westward shift CMIP6-HighResMIP models Pacific walker circulation
在线阅读 下载PDF
Differentiated Cloud-Radiation Characteristics over East Asian Subtropical and Tropical Regions Revealed by CMIP6 Models
8
作者 WU Rui-xue LI Jian-dong +4 位作者 XU Jian-jun ZHANG Yu LIAO Xiao-qing LIU Chun-lei DU Zhen-cai 《Journal of Tropical Meteorology》 2025年第1期43-63,共21页
Pronounced climatic differences occur over subtropical South China(SC)and tropical South China Sea(SCS)and understanding the key cloud-radiation characteristics is essential to simulating East Asian climate.This study... Pronounced climatic differences occur over subtropical South China(SC)and tropical South China Sea(SCS)and understanding the key cloud-radiation characteristics is essential to simulating East Asian climate.This study investigated cloud fractions and cloud radiative effects(CREs)over SC and SCS simulated by CMIP6 atmospheric models.Remarkable differences in cloud-radiation characteristics appeared over these two regions.In observations,considerable amounts of low-middle level clouds and cloud radiative cooling effect appeared over SC.In contrast,high clouds prevailed over SCS,where longwave and shortwave CREs offset each other,resulting in a weaker net cloud radiative effect(NCRE).The models underestimated NCRE over SC mainly due to weaker shortwave CRE and less cloud fractions.Conversely,most models overestimated NCRE over SCS because of stronger shortwave CRE and weaker longwave CRE.Regional CREs were closely linked to their dominant cloud fractions.Both observations and simulations showed a negative spatial correlation between total(low)cloud fraction and shortwave CRE over SC,especially in winter,and exhibited a positive correlation between high cloud fraction and longwave CRE over these two regions.Compared with SCS,most models overestimated the spatial correlation between low(high)cloud fraction and SWCRE(LWCRE)over SC,with larger bias ranges among models,indicating the exaggerated cloud radiative cooling(warming)effect caused by low(high)clouds.Moreover,most models struggled to describe regional ascent and its connection with CREs over SC while they can better reproduce these connections over SCS.This study further suggests that reasonable circulation conditions are crucial to simulating well cloud-radiation characteristics over the East Asian regions. 展开更多
关键词 cloud fraction cloud radiative effect CMIP6 model South China South China Sea
在线阅读 下载PDF
An Integrated Experimental-Simulation Calibration Method for the Constitutive Model of 6005A-T6 Aluminum Alloy Welds
9
作者 Yu Zhu Lele Zhang +1 位作者 Weiyuan Dou Wen Liu 《Chinese Journal of Mechanical Engineering》 2025年第1期233-245,共13页
Due to the different microstructures caused by the heat source effect,welding joints exhibit significant differences in mechanical properties compared to the base material.Precise characterization of the constitutive ... Due to the different microstructures caused by the heat source effect,welding joints exhibit significant differences in mechanical properties compared to the base material.Precise characterization of the constitutive characteristics of the welded joint requires a large number of repetitive experiments,which are costly,inefficient,and have limited accuracy improvements.This paper proposes an integrated experimental-simulation-based inverse calibration method,which establishes a calibration optimization problem based on the corresponding constitutive model and a finite element calculation model built by the distribution of hardness in the weldment.Using the global tensile force-displacement curve of the MIG-welded 6005A-T6 aluminum alloy specimen and the experimental data of local deformation with time change obtained from DIC(Digital Image Correlation),the parameters involved in the constitutive models are optimized accordingly.This method can directly obtain the constitutive characteristics of the weldment under conditions of limited experiments and insufficient data.Additionally,the adaptability of the constitutive model to the calibration method and the influence of optimization results are discussed and analyzed.The results indicate that the global force-displacement response of the non-saturated Ramberg-Osgood(R-O)model is in the best agreement with that of the experimental data,and the energy error is only 2.62%,followed by the MPL model,while the saturation-based Voce model shows the largest simulation error in terms of the presented object.Furthermore,the simulation results of R-O,Voce,and MPL models in the local area are far superior to traditional fitting methods. 展开更多
关键词 6005A-T6 aluminum alloy MIG-weld joint Parameter calibration Elastic-plastic constitutive model DIC
在线阅读 下载PDF
6G Digital Twin Enabled Channel Modeling for Beijing Central Business District
10
作者 LU Mengyuan BAI Lu +3 位作者 HAN Zengrui HUANG Ziwei LU Shiliang CHENG Xiang 《ZTE Communications》 2025年第2期31-45,共15页
A novel digital twin(DT)enabled channel model for 6G vehicular communications in Beijing Central Business District(Beijing CBD)is proposed,which can support the design of intelligent transportation systems(ITSs).A DT ... A novel digital twin(DT)enabled channel model for 6G vehicular communications in Beijing Central Business District(Beijing CBD)is proposed,which can support the design of intelligent transportation systems(ITSs).A DT space for Beijing CBD is constructed,and two typical transportation periods,i.e.,peak and off-peak hours,are considered to characterize the vehicular communication channel better.Based on the constructed DT space,a DT-enabled vehicular communication dataset is developed,including light detection and ranging(LiDAR)point clouds,RGB images,and channel information.With the assistance of LiDAR point clouds and RGB images,the scatterer parameters,including number,distance,angle,power,and velocity,are analyzed under different transportation periods.The channel non-stationarity and consistency are mimicked in the proposed model.The key channel statistical properties are derived and simulated.Compared to ray-tracing(RT)results,the accuracy of the proposed model is verified. 展开更多
关键词 DT channel modeling 6G vehicular communications Beijing CBD DT-enabled vehicular communication dataset
在线阅读 下载PDF
Experimental and Neural Network Modeling of the Thermal Behavior of an Agricultural Greenhouse Integrated with a Phase Change Material(CaCl_(2)⋅6H_(2)O)
11
作者 Abdelouahab Benseddik Djamel Daoud +4 位作者 Ahmed Badji Hocine Bensaha Tarik Hadibi Yunfeng Wang Li Ming 《Energy Engineering》 2025年第12期5021-5037,共17页
In Saharan climates,greenhouses face extreme diurnal temperature fluctuations that generate thermal stress,reduce crop productivity,and hinder sustainable agricultural practices.Passive thermal storage using Phase Cha... In Saharan climates,greenhouses face extreme diurnal temperature fluctuations that generate thermal stress,reduce crop productivity,and hinder sustainable agricultural practices.Passive thermal storage using Phase Change Materials(PCM)is a promising solution to stabilize microclimatic conditions.This study aims to evaluate experimentally and numerically the effectiveness of PCM integration for moderating greenhouse temperature fluctuations under Saharan climatic conditions.Two identical greenhouse prototypes were constructed in Ghardaia,Algeria:a reference greenhouse and a PCM-integrated greenhouse using calcium chloride hexahydrate(CaCl_(2)⋅6H_(2)O).Thermal performance was assessed during a five-day experimental period(7–11May 2025)under severe ambient conditions.To complement this,a Nonlinear Auto-Regressive with eXogenous inputs(NARX)neural network model was developed and trained using a larger dataset(7–25 May 2025)to predict greenhouse thermal dynamics.The PCM greenhouse reduced peak daytime air temperature by an average of 8.14℃and decreased the diurnal temperature amplitude by 53.6%compared to the reference greenhouse.The NARX model achieved high predictive accuracy(R^(2)=0.990,RMSE=0.425℃,MAE=0.223℃,MBE=0.008℃),capturing both sensible and latent heat transfer mechanisms,including PCM melting and solidification.The combined experimental and predictive modeling results confirm the potential of PCM integration as an effective passive thermal regulation strategy for greenhouses in arid regions.This approach enhances microclimatic stability,improves energy efficiency,and supports the sustainability of protected agriculture under extreme climatic conditions. 展开更多
关键词 Agricultural greenhouse phase changematerial(PCM) CaCl_(2)⋅6H_(2)O thermal regulation NARX neural network experimental study modeling
在线阅读 下载PDF
“Water”accelerated B(C_(6)F_(5))_(3)-catalyzed Mukaiyama-aldol reaction:Outer-sphere activation model
12
作者 Zhenguo Zhang Lanyang Li +6 位作者 Xinlong Zong Yongheng Lv Shuanglei Liu Liang Ji Xuefei Zhao Zhenhua Jia Teck-Peng Loh 《Chinese Chemical Letters》 2025年第7期334-339,共6页
A“water”accelerated metal-free catalytic system has been discovered for the Mukaiyama-aldol reaction.The system involves the use of B(C_(6)F_(5))_(3) as a catalyst,which is water-tolerant and able to activate the ca... A“water”accelerated metal-free catalytic system has been discovered for the Mukaiyama-aldol reaction.The system involves the use of B(C_(6)F_(5))_(3) as a catalyst,which is water-tolerant and able to activate the carbonyl group through a hydrogen bonding network generated by the catalyst.This activation method allows the reactions to be performed with very low catalyst loading,as low as 0.5 mol%.The scope of substrates is broad and a wide variety of functional groups are well tolerated.Diverse aliphatic aldehydes,aromatic aldehydes,unsaturated aldehydes and aromatic ketones coupled with silyl enol ethers/silyl ketone acetals to generate their correspondingβ-hydroxy carbonyl compounds in moderate to good yields.This discovery represents a significant advancement in the field of organic synthesis,as it provides a new,practical and sustainable solution for carbon-carbon bond formation in water. 展开更多
关键词 B(C_(6)F_(5))_(3)-catalysis Hydrogen bonding network Water-acceleration Mukaiyama-aldol reaction Outer-sphere activation model
原文传递
Modeling of Precipitation over Africa:Progress,Challenges,and Prospects
13
作者 A.A.AKINSANOLA C.N.WENHAJI +21 位作者 R.BARIMALALA P.-A.MONERIE R.D.DIXON A.T.TAMOFFO M.O.ADENIYI V.ONGOMA I.DIALLO M.GUDOSHAVA C.M.WAINWRIGHT R.JAMES K.C.SILVERIO A.FAYE S.S.NANGOMBE M.W.POKAM D.A.VONDOU N.C.G.HART I.PINTO M.KILAVI S.HAGOS E.N.RAJAGOPAL R.K.KOLLI S.JOSEPH 《Advances in Atmospheric Sciences》 2026年第1期59-86,共28页
In recent years,there has been an increasing need for climate information across diverse sectors of society.This demand has arisen from the necessity to adapt to and mitigate the impacts of climate variability and cha... In recent years,there has been an increasing need for climate information across diverse sectors of society.This demand has arisen from the necessity to adapt to and mitigate the impacts of climate variability and change.Likewise,this period has seen a significant increase in our understanding of the physical processes and mechanisms that drive precipitation and its variability across different regions of Africa.By leveraging a large volume of climate model outputs,numerous studies have investigated the model representation of African precipitation as well as underlying physical processes.These studies have assessed whether the physical processes are well depicted and whether the models are fit for informing mitigation and adaptation strategies.This paper provides a review of the progress in precipitation simulation overAfrica in state-of-the-science climate models and discusses the major issues and challenges that remain. 展开更多
关键词 RAINFALL MONSOON climate modeling CORDEX CMIP6 convection-permitting models
在线阅读 下载PDF
Assessing future drought evolution and driving mechanisms in the Weigan River Basin under CMIP6 climate scenarios
14
作者 WANG Wenbo LIN Li +1 位作者 CHEN Dandan YANG Jiayun 《Journal of Arid Land》 2026年第2期235-262,共28页
In the northern Tarim River Basin,the Weigan River Basin is a critical endorheic system characterized by extreme aridity,where drought poses a major natural hazard to agricultural production and ecological stability.T... In the northern Tarim River Basin,the Weigan River Basin is a critical endorheic system characterized by extreme aridity,where drought poses a major natural hazard to agricultural production and ecological stability.This study assessed the future evolution of drought under climate change by employing the standardized moisture anomaly index(SZI)on the basis of multi-model the Coupled Model Intercomparison Project Phase 6(CMIP6)simulations under historical conditions(1970–2014)and future scenarios(shared socioeconomic pathway(SSP)1-2.6,SSP2-4.5,SSP3-7.0 and SSP5-8.5 for 2015–2100).The results show that precipitation–evapotranspiration anomalies are projected to first decline but then increase over time,with increased fluctuations and uncertainty under high-emission scenarios(SSP5-8.5).These trends indicate intensifying drought risks and reveal a strong influence of emission pathways on regional water cycling.Temporal analysis of SZI indicates a transition from wetting to drying under lowand medium-emission pathways(SSP1-2.6 and SSP2-4.5),whereas high-emission scenarios are characterized by persistent drying and increased variability.The significant lower-tail dependence(0.271)observed under SSP2-4.5 and SSP5-8.5 suggests that extreme droughts may be subject to nonlinear co-amplification across scenarios.The frequency of moderate and more severe drought events is expected to increase substantially,especially under SSP5-8.5,where drought occurrence is predicted to extend into spring and autumn and become more evenly distributed throughout the year.Spatially,drought duration shows significant positive autocorrelation across all scenarios,with hot spots consistently concentrated in the southern and southeastern regions of the basin.Random forest analysis,interpreted as association-based pattern attribution,indicates that meteorological variables(precipitation and potential evapotranspiration(PET))make the greatest contributions to the hot spot pattern,followed by topography and soil moisture.Among land use categories,farmland generally shows higher drought sensitivity than other land use types,as reflected by its relative contribution patterns across scenarios.The spatial pattern of drought is statistically structured by climatic forcing,surface conditions,and soil moisture status,reflecting their coupled associations with hot spot occurrence.In addition,a drought spatial uncertainty index was constructed from multi-scenario hot spot maps,revealing spatially heterogeneous structural variability throughout the basin.Correlation analysis further highlights strong internal couplings among environmental variables(e.g.,elevation-linked hydroclimatic gradients and grassland–bare soil contrasts).These findings offer a scientific basis for developing region-specific drought monitoring and adaptation strategies under future climate change conditions. 展开更多
关键词 Coupled model Intercomparison Project Phase 6(CMIP6) Weigan River Basin standardized moisture anomaly index(SZI) drought characteristics climate change random forest Shapley Additive exPlanations(SHAP)
在线阅读 下载PDF
基于CMIP6的岷沱江流域径流预估
15
作者 江楠 倪福全 +4 位作者 邓玉 向军 吴明炎 康文东 岳紫莹 《水生态学杂志》 北大核心 2026年第1期25-36,共12页
揭示岷沱江流域未来径流变化趋势,为岷沱江流域水资源管理和决策提供科学依据。基于SWAT模型和第六次国际耦合模式比较计划(CMIP6),采用6个全球气候模式(GCMs)的多模式集合平均(MME),将基准期(1981—2014年)与未来2个时期2017—2050年和... 揭示岷沱江流域未来径流变化趋势,为岷沱江流域水资源管理和决策提供科学依据。基于SWAT模型和第六次国际耦合模式比较计划(CMIP6),采用6个全球气候模式(GCMs)的多模式集合平均(MME),将基准期(1981—2014年)与未来2个时期2017—2050年和2057—2090年对比,评估4种不同的共享社会经济路径(SSPs)下岷沱江流域未来径流情况。结果表明:(1)SWAT模型在岷沱江流域径流模拟中具有较好的适用性,研究区7个水文监测站月径流模拟效果较好;(2)采用MME模拟气温和降水相关系数分别为0.99和0.93,模拟值与观测值有极高的相似度;(3)相较基准期,在各种情景下,未来岷沱江流域年均气温呈增加趋势,SSP5-8.5增温最为明显,年均降水量呈波动上升趋势;(4)不同情景下的未来2个时期,岷沱江流域的径流量将会减少,2017—2050年期间径流减少的幅度大于2057—2090年,减少的区域集中在岷江上游、沱江下游和青衣江流域。降雨的增加并不能完全消弭流域持续温升驱动的径流量减少。 展开更多
关键词 第六次国际耦合模式比较计划 SWAT模型 径流 集合预估 岷沱江流域
在线阅读 下载PDF
基于ADA、GR、VE、Hb、RBC的G6PD缺乏症列线图诊断模型构建及其诊断效能验证
16
作者 吕碧绿 罗文英 《检验医学与临床》 2026年第3期358-365,共8页
目的基于血清腺苷脱氨酶(ADA)、谷胱甘肽还原酶(GR)、维生素E(VE)、血红蛋白(Hb)、红细胞计数(RBC)构建葡萄糖-6-磷酸脱氢酶(G6PD)缺乏症列线图诊断模型,并进行效能验证。方法选取2022年9月1日至2024年12月31日在广东省茂名市妇幼保健... 目的基于血清腺苷脱氨酶(ADA)、谷胱甘肽还原酶(GR)、维生素E(VE)、血红蛋白(Hb)、红细胞计数(RBC)构建葡萄糖-6-磷酸脱氢酶(G6PD)缺乏症列线图诊断模型,并进行效能验证。方法选取2022年9月1日至2024年12月31日在广东省茂名市妇幼保健院接受G6PD筛查的521例就诊者作为研究对象,根据《葡萄糖-6-磷酸脱氢酶缺乏症新生儿筛查、诊断和治疗专家共识》中G6PD缺乏症的诊断标准将研究对象分为病例组(243例)和对照组(278例)。按7∶3比例采用分层抽样法将数据集随机分为训练集和验证集。收集所有研究对象的基线资料,并检测ADA、GR、VE水平。采用LASSO回归分析筛选变量,再用多因素Logistic回归分析G6PD缺乏症发生的影响因素,构建列线图诊断模型。绘制受试者工作特征(ROC)曲线、校准曲线及决策曲线对模型进行效能验证。结果训练集中病例组的总胆红素(TBIL)、直接胆红素(DBIL)、间接胆红素(IBIL)、ADA、GR水平高于对照组,VE、Hb水平及RBC低于对照组,差异均有统计学意义(P<0.05)。通过LASSO回归筛选出IBIL、DBIL、VE、ADA、GR、Hb、RBC作为核心变量,多因素Logistic回归分析结果显示,ADA、GR水平升高为G6PD缺乏症发生的独立危险因素(P<0.05),RBC、VE、Hb水平升高为G6PD缺乏症发生的独立保护因素(P<0.05)。据此构建的诊断模型表达式为Logit(P)=2.89-0.08 X_(VE)+0.85 X_(ADA)+0.92 X_(GR)-0.73 X_(Hb)-1.47 X_(RBC)。ROC曲线分析结果显示,G6PD缺乏症的列线图诊断模型在训练集中诊断G6PD缺乏症的曲线下面积(AUC)为0.98,在验证集中诊断G6PD缺乏症的AUC为0.99。Hosmer-Lemeshow检验结果为χ_(训练集)^(2)=4.12,P_(训练集)=0.763,χ_(验证集)^(2)=3.85,P_(验证集)=0.802,诊断概率与实际观察值高度贴合。训练集和验证集决策曲线分析结果显示,模型在阈值0.00~1.00内具有临床净收益。结论VE缺乏、ADA及GR水平升高、Hb及RBC水平降低与G6PD缺乏症密切相关,本研究构建的G6PD缺乏症列线图诊断模型具有较优的稳定性和诊断效能,为临床早期筛查提供了新工具。 展开更多
关键词 葡萄糖-6-磷酸脱氢酶缺乏症 腺苷脱氨酶 谷胱甘肽还原酶 维生素E 诊断模型
暂未订购
采用TRIP2.0软件计算DLR-F6构型的阻力 被引量:19
17
作者 王运涛 王光学 张玉伦 《空气动力学学报》 EI CSCD 北大核心 2009年第1期108-113,共6页
采用"亚跨超CFD软件平台"(TRIP2.0)数值模拟了DLR-F6构型,主要目的是通过计算DLR-F6构型的安装阻力考察TRIP2.0软件的数值模拟精度,并为运输机构型的气动特性计算积累经验。本文数值模拟采用的多块对接网格,测压和测力的试验... 采用"亚跨超CFD软件平台"(TRIP2.0)数值模拟了DLR-F6构型,主要目的是通过计算DLR-F6构型的安装阻力考察TRIP2.0软件的数值模拟精度,并为运输机构型的气动特性计算积累经验。本文数值模拟采用的多块对接网格,测压和测力的试验结果均来自AIAA CFD Drag Prediction Workshop Ⅱ(DPWⅡ),对比计算结果采用了CFL3D的结果。本文详细研究了网格密度、湍流模型对DLR-F6翼身组合体和翼/身/架/舱复杂组合体两种构型的的总体气动特性和压力分布的影响,计算结果与相应的试验结果取得了较好的一致。本文采用SST两方程模型计算两种构型均得到了网格收敛结果;不同的湍流模型对压差阻力影响较小,对摩擦阻力影响较大;不同的网格密度和湍流模型对压力分布影响较小。 展开更多
关键词 TRIP2.0 dlr-f6 阻力计算 湍流模型
在线阅读 下载PDF
DLR-F6翼身组合体数值计算 被引量:17
18
作者 张耀冰 邓有奇 +1 位作者 吴晓军 孟凡菊 《空气动力学学报》 CSCD 北大核心 2011年第2期163-169,共7页
使用自行研制的混合网格亚跨超声速流场解算器程序MFlow计算了AIAA第三届阻力会议提供的DLR-F6及其带整流装置FX2B情况下的阻力。重点分析了两者的网格收敛特性、阻力极曲线以及压力分布等,并与阻力会议的各个软件的计算结果进行比较。... 使用自行研制的混合网格亚跨超声速流场解算器程序MFlow计算了AIAA第三届阻力会议提供的DLR-F6及其带整流装置FX2B情况下的阻力。重点分析了两者的网格收敛特性、阻力极曲线以及压力分布等,并与阻力会议的各个软件的计算结果进行比较。详细分析了DLR-F6翼身结合处后缘附近网格精度对分离气泡计算的影响。计算结果表明,MFlow程序的计算精度与国外软件相近,能够为阻力计算提供比较精确的结果。 展开更多
关键词 dlr-f6翼身组合体 数值模拟 阻力计算
在线阅读 下载PDF
DLR-F6翼身组合体阻力计算 被引量:6
19
作者 王运涛 王光学 张玉伦 《计算物理》 CSCD 北大核心 2008年第2期145-150,共6页
采用"亚跨超CFD软件平台"(TRIP2.0)数值模拟DLR-F6翼身组合体构型,采用的多块对接网格、测压和测力的试验结果均来自美国AIAA阻力计算小组,对比计算结果采用CFL3D的结果.详细研究网格密度、湍流模型对DLR-F6翼身组合体构型的... 采用"亚跨超CFD软件平台"(TRIP2.0)数值模拟DLR-F6翼身组合体构型,采用的多块对接网格、测压和测力的试验结果均来自美国AIAA阻力计算小组,对比计算结果采用CFL3D的结果.详细研究网格密度、湍流模型对DLR-F6翼身组合体构型的总体气动特性和压力分布的影响,计算结果与相应的试验结果较一致.采用SST两方程模型得到网格收敛结果;不同的湍流模型对压差阻力影响较小,对摩擦阻力影响较大;不同的网格密度和湍流模型对压力分布影响较小. 展开更多
关键词 TRIP2.0 DLR—F6 DPWⅡ 阻力 湍流模型
在线阅读 下载PDF
A modified Johnson-Cook model for NC warm bending of large diameter thin-walled Ti-6Al-4V tube in wide ranges of strain rates and temperatures 被引量:7
20
作者 陶智君 樊晓光 +2 位作者 杨合 马俊 李恒 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2018年第2期298-308,共11页
Numerical control(NC) warm bending is a proven strategy to form the large diameter thin-walled(LDTW) Ti-6 Al-4 V tubes, which are typical light-weight and high-performance structural components urgently required i... Numerical control(NC) warm bending is a proven strategy to form the large diameter thin-walled(LDTW) Ti-6 Al-4 V tubes, which are typical light-weight and high-performance structural components urgently required in many industries. In virtue of unveiling the thermo-mechanical coupled deformation behaviors, uniaxial tensile tests were conducted on Ti-6 Al-4 V tube within wide ranges of temperatures(25-600 ℃) and strain rates(0.00067-0.1 s~(-1)). Moreover, a modified Johnson-Cook(JC) model is proposed with a consideration of nonlinear strain rate hardening and the interaction between strain hardening and thermal softening. Resultantly, the present model gives more accurate predictions for flow stress over the entire deformation ranges and the maximum error decreases by about 90%. By employing proposed model to NC warm bending, preferable precision is obtained in predicting forming defects including fracture, wrinkling and over thinning. The present work lays foundation for the forming limit prediction and process optimization in NC warm bending of LDTW Ti-6 Al-4 V tubes. 展开更多
关键词 NC warm bending Ti-6Al-4V tube Johnson-Cook model
在线阅读 下载PDF
上一页 1 2 51 下一页 到第
使用帮助 返回顶部