The microbial degradation of aromatic organic pollutants is incomplete due to their metabolic characteristics,which can easily produce certain highly toxic intermediates.Therefore,this article designs a dual template ...The microbial degradation of aromatic organic pollutants is incomplete due to their metabolic characteristics,which can easily produce certain highly toxic intermediates.Therefore,this article designs a dual template molec-ularly imprinted sensor(DTMIP/Fe-Mn@C)for iron manganese metal nanomaterials,prepared Fe-Mn@C com-posite materials by a one pot method were coated on the surface of glassy carbon electrodes and covered with molecularly imprinted membranes through electropolymerization and elution methods,achieving real-time de-tection of specific intermediate products 2-methylbutyric acid(2-MBA)and 3-methylbutyric acid(3-MBA)de-graded by azo dyes.In order to determine the detection sensitivity and intensity range of the sensor,optimization experiments were conducted on various parameters that affect the detection performance,such as the type of func-tional monomer and its composition ratio with the template molecule,detection time window,environmental pH value,etc.Finally,o-Phenylenediamine was determined as the functional monomer,with a molar ratio of 1:1:6 to the template molecules 2-MBA and 3-MBA.Electrochemical testing was conducted in a neutral environment with an incubation time of 5 min and pH=7.The results indicate that the sensor has a relatively wide detection range,high sensitivity,obvious recognition features,and excellent stability for 2-MBA and 3-MBA.This new dual template molecularly imprinted sensor can quickly and accurately determine the safety of highly toxic interme-diates in the degradation process of aromatic organic pollutants,providing a theoretical basis and application potential for trace detection and real-time monitoring.展开更多
While nuclear energy represents a low-carbon and high-efficiency energy source that plays a vital role in the global energy mix,the limitations of spent fuel reprocessing technology pose a major challenge to its susta...While nuclear energy represents a low-carbon and high-efficiency energy source that plays a vital role in the global energy mix,the limitations of spent fuel reprocessing technology pose a major challenge to its sustainable development.The PUREX(plutonium uranium redox extraction)process is currently the dominant nuclear fuel reprocessing technology in the world.However,the key extractant in this process is tributyl phosphate(TBP),which degrades under intense radiation,high temperatures,and strong acidity.This leads to the production of dibutyl phosphate,monobutyl phosphate,and other degradation byproducts,which may reduce the extraction efficiency and trigger third-phase formation and equipment corrosion.This paper systematically reviews the degradation mechanisms of TBP and its diluents,the analytical technique suitable for characterizing degradation products,and the impact of degradation products on the post-treatment process.Additionally,optimization strategies employed for suppressing third-phase formation are discussed.This study offers a theoretical foundation and technical insights in optimizing the PUREX process and ensuring the safe operation of the post-treatment process.展开更多
The escalating pace of industrialization has significantly intensified water pollution challenges,for instance,the persistent organic pollutants like methyl orange(MO).Conventional remediation techniques,such as adsor...The escalating pace of industrialization has significantly intensified water pollution challenges,for instance,the persistent organic pollutants like methyl orange(MO).Conventional remediation techniques,such as adsorption and biological degradation,are often hampered by low efficiency and the risk of secondary pollution.Photocatalysis emerges as a promising sustainable alternative;however,the benchmark material titanium dioxide(TiO_(2))suffers from its intrinsic limitations,notably its wide bandgap energy(≥3.4 eV)restricting its activity to the region of the ultraviolet light and its rapid recombination of photogenerated charge carriers.To overcome these constraints,this research focused on synthesizing novel TiO_(2)/Sn_(3)O_(4) heterojunction composite photocatalysts via a solvothermal approach.Comprehensive characterization techniques confirmed the successful formation of the composite,which revealed that ultrathin Sn3O4 nanosheets uniformly coated TiO_(2) nanospheres.This unique architecture effectively reduced the overall crystallinity and introduced the beneficial oxygen vacancies.Under visible-light irradiation(λ≥420 nm),the optimized TiO_(2)/Sn3O4 composite exhibited the exceptional photocatalytic performance,which achieved 96%degradation of MO within just 60 minutes.The calculated apparent kinetic rate constant(0.103 min^(-1))was remarkably(5.15 times)higher than that of pristine TiO_(2).ESR experiments identified that hydroxyl radicals(·OH)was the predominant active species driving the degradation.Furthermore,cyclic degradation tests demonstrated its excellent material stability,with the composite retaining 85%of its initial efficiency after four consecutive reuse cycles.This work underscored the synergistic effects within the TiO_(2)/Sn_(3)O_(4) heterojunction,which significantly enhanced the visible-light absorption,charge separation,and photocatalytic activity,which provided the valuable insights for designing efficient,stable catalysts for the advanced environmental remediation applications.展开更多
The escalating global issues of water scarcity and pollution emphasize the critical need for the rapid development of efficient and eco-friendly water treatment technologies.Photoelectrocatalytic technology has emerge...The escalating global issues of water scarcity and pollution emphasize the critical need for the rapid development of efficient and eco-friendly water treatment technologies.Photoelectrocatalytic technology has emerged as a promising solution for effectively degrading refractory organic pollutants in water under light conditions.This review delves into the advancements made in the field,focusing on strategies to enhance the generation of active species by modulating the micro-interface of the photoanode.Strategies,such as morphological control,element doping,introduction of surface oxygen vacancies,and construction of heterostructures,significantly improve the separation efficiency of photogenerated charges and the generation of active species,thereby boosting the efficiency of photoelectrocatalytic performance.Furthermore,the review explores the potential applications of photoelectrocatalytic technology in organic pollutant degradation in solutions.It also outlines the current challenges and future development directions.Despite its remarkable laboratory success,practical implementation of photoelectrocatalytic technology encounters obstacles related to stability,cost-effectiveness,and operational efficiency.Future investigations need to focus on optimizing the performance of photoelectrocatalytic materials and exploring strategies for upscaling their application in real water treatment scenarios.展开更多
The increasing production and release of synthetic organic chemicals,including pharmaceuticals,into our envi-ronment has allowed these substances to accumulate in our surface water systems.Current purification technol...The increasing production and release of synthetic organic chemicals,including pharmaceuticals,into our envi-ronment has allowed these substances to accumulate in our surface water systems.Current purification technolo-gies have been unable to eliminate these pollutants,resulting in their ongoing release into aquatic ecosystems.This study focuses on cloperastine(CPS),a cough suppressant and antihistamine medication.The environmental impact of CPS usage has become a concern,mainly due to its increased detection during the COVID-19 pandemic.CPS has been found in wastewater treatment facilities,effluents from senior living residences,river waters,and sewage sludge.However,the photosensitivity of CPS and its photodegradation profile remain largely unknown.This study investigates the photodegradation process of CPS under simulated tertiary treatment conditions using UV photolysis,a method commonly applied in some wastewater treatment plants.Several transformation prod-ucts were identified,evaluating their kinetic profiles using chemometric approaches(i.e.,curve fitting and the hard-soft multivariate curve resolution-alternating least squares(HS-MCR-ALS)algorithm)and calculating the reaction quantum yield.As a result,three different transformation products have been detected and correctly identified.In addition,a comprehensive description of the kinetic pathway involved in the photodegradation process of the CPS drug has been provided,including observed kinetic rate constants.展开更多
In this work,we constructed a three-dimensional electrochemical system(3D-ECO),which included the cathode and anode electrode plates,as well as the screening of three-dimensional particle electrodes and parameter opti...In this work,we constructed a three-dimensional electrochemical system(3D-ECO),which included the cathode and anode electrode plates,as well as the screening of three-dimensional particle electrodes and parameter opti-mization,for the degradation of landfill leachate(LL)containing elevated levels of tetracycline(TC),and explored its mechanism of action.Firstly,titanium-based ruthenium-iridium(Ti/RuO_(2)-IrO_(2)),titanium-based ruthenium-iridium-platinum(Ti/Pt-RuO_(2)-IrO_(2)),and titanium-based tin-antimony(Ti/SnO_(2)-Sb_(2)O_(3))were employed as an-odes in the electrocatalytic oxidation system,with titanium and stainless steel plates serving as cathodes,to construct the optimal two-dimensional electrocatalytic oxidation system(2D-ECO)through cross-comparison ex-periments.Subsequently,using granular activated carbon(GAC),coconut shell biochar(CBC),walnut shell carbon(WBC),and bamboo charcoal(BBC)as particle electrodes,a 3D-ECO system was developed.The influence of var-ious operational parameters on treating TC-containing LL was investigated.The optimal operating parameters obtained from the study was:pH=5,current density of 30 mA/cm^(2),particle dosage of 7 g/L,particle size ranging from 1.70 to 2.00 mm,and electrode spacing of 4 cm.Under these conditions,the COD removal rate of 3D-ECO within three hours was 90.25%,the TC removal rate was 72.41%,and the NH_(3)-N removal rate was 39.52%.The removal of TC followed a pseudo-first-order kinetic model.Additionally,degradation mechanisms were elucidated through electron paramagnetic resonance(EPR)spectrometer and Tert-Butanol(TBA)quenching experiments,indicating that the degradation primarily occurred through a non-radical(1O_(2))pathway.This re-search offers a comprehensive analysis of the simultaneous breakdown of intricate LL matrices and TC,enhancing our comprehension of the degradation processes and underlying mechanisms.展开更多
Oxidative magnetization has attracted great attention as an efficient strategy for modulating physiochemical properties of magnetic biochar.In this paper,a K_(2)FeO_(4)-involving hydrothermal oxidative magnetization w...Oxidative magnetization has attracted great attention as an efficient strategy for modulating physiochemical properties of magnetic biochar.In this paper,a K_(2)FeO_(4)-involving hydrothermal oxidative magnetization was explored to regulate multiple micro-structures for manufacture magnetic hydrochar(MHC)for Fenton-like degradation of tetracycline in aqueous solution.Diverse shapes of Fe_(3)O_(4) and nano zero-valent iron(nZVI)were doped with abundant oxygen containing groups and persistent free radicals(PFRs).Multiple catalysis sites including iron species,PFRs,oxygen containing groups,and graphite defects contributed to accelerate the Fenton-like degradation with synergistic effect.Notably,MHC achieved a tetracycline removal rate of 99% within 60 min at 50 mg/L,with a total organic carbon(TOC)removal rate of 35%.Furthermore,after four cycles of reuse,the degradation efficiency slightly decreased to 93%.This study highlights the potential of magnetic hydrochar with multiple catalytic sites in the effective and sustainable degradation of pollutants.展开更多
Superoxide dismutase 1(SOD1)is a thermodynamically stable,zinc and copper binding homodimeric enzyme responsible for breaking down superoxide radicals.More than 200,mostly missense,mutations spread throughout the SOD1...Superoxide dismutase 1(SOD1)is a thermodynamically stable,zinc and copper binding homodimeric enzyme responsible for breaking down superoxide radicals.More than 200,mostly missense,mutations spread throughout the SOD1 gene are associated with the fatal neurodegenerative disease,amyotrophic lateral sclerosis(ALS).A unifying feature of ALS-associated SOD1 mutations is the destabilization of the SOD1 protein structure,increasing the propensity for misfolding and subsequent pathological aggregation.Post-mortem analysis of SOD1-associated ALS tissue shows the accumulation of misfolded SOD1 protein and ubiquitinated SOD1 inclusions within motor neurons.Misfolded SOD1 accumulation and aggregates are implicated in cellular dysfunction via a number of disparate but critical processes,including endoplasmic reticulum stress,oxidative damage,proteasome dysfunction,axonal transport abnormalities and synaptic dysfunction;culminating in motor neuron degeneration associated with ALS.展开更多
The excessive use of pesticides has exacerbated environmental pollution due to herbicide residues,while their persistent toxicity poses serious challenges to global ecological security.A magnetically recyclable CoFe_(...The excessive use of pesticides has exacerbated environmental pollution due to herbicide residues,while their persistent toxicity poses serious challenges to global ecological security.A magnetically recyclable CoFe_(2)O_(4)/BiOBr S-scheme heterojunctions was prepared by microwave-assisted co-precipitation method for photocatalytic degradation of Diuron(DUR) in water.The formation of S-scheme heterojunction enhances electron transfer and charge separation,which was demonstrated by free radical trapping,electrochemical experiments,and DFT calculations.The magnetic CoFe_(2)O_(4)/BiOBr catalysts can achieve 99.9 %removal of diuron in 50 min under visible light irradiation.Furthermore,the system maintains stable performance across a broad p H range(3-9),enabling adaptation to diverse water environments,effective elimination of multiple pollutants,and strong resistance to ionic interference.Using magnetic recovery,CoFe_(2)O_(4)/BiOBr exhibits a high removal rate of 99 % and a markedly low ion leaching rate(<20 μg/L) after six cycles photocatalytic process,confirming its excellent stability and durability.According to HPLCQTOF-MS and DFT calculation,the main ways of DUR degradation include dechlorinated hydroxylation,dealkylation and hydroxylation of aromatic ring and side chain.Toxicity analysis showed that the toxicity of the intermediates generated during degradation was generally lower than that of DUR.The magnetic CoFe_(2)O_(4)/BiOBr S-scheme heterojunction developed in this study exhibits excellent photocatalytic performance,high applicability,good stability,and durability,providing an effective magnetic for the removal of refractory pollutants.展开更多
To address the issues of insufficient and imbalanced data samples in proton exchange membrane fuel cell(PEMFC)performance degradation prediction,this study proposes a data augmentation-based model to predict PEMFC per...To address the issues of insufficient and imbalanced data samples in proton exchange membrane fuel cell(PEMFC)performance degradation prediction,this study proposes a data augmentation-based model to predict PEMFC performance degradation.Firstly,an improved generative adversarial network(IGAN)with adaptive gradient penalty coefficient is proposed to address the problems of excessively fast gradient descent and insufficient diversity of generated samples.Then,the IGANis used to generate datawith a distribution analogous to real data,therebymitigating the insufficiency and imbalance of original PEMFC samples and providing the predictionmodel with training data rich in feature information.Finally,a convolutional neural network-bidirectional long short-termmemory(CNN-BiLSTM)model is adopted to predict PEMFC performance degradation.Experimental results show that the data generated by the proposed IGAN exhibits higher quality than that generated by the original GAN,and can fully characterize and enrich the original data’s features.Using the augmented data,the prediction accuracy of the CNN-BiLSTM model is significantly improved,rendering it applicable to tasks of predicting PEMFC performance degradation.展开更多
Objective:Osteoarthritis(OA)is a degenerative joint disease characterized by extracellular matrix(ECM)degradation,chondrocyte apoptosis,and chronic inflammation.Cartilage destruction and ECM degeneration contribute to...Objective:Osteoarthritis(OA)is a degenerative joint disease characterized by extracellular matrix(ECM)degradation,chondrocyte apoptosis,and chronic inflammation.Cartilage destruction and ECM degeneration contribute to joint function loss and disability.Signal transducer and activator of transcription 3(STAT3)up-regulates the expression of MMP-13,which degrades collagen Ⅱ.Our previous study found that 5,7,3',4'-tetramethoxyflavone(TMF)exhibited protective effects on OA chondrocytes.This study aims to investigate the protective role of TMF in inhibiting ECM degradation by mediating the Sirt1/STAT3 signaling pathway.Methods:Rat OA models were established by the injection of monosodium iodoacetate(MIA).Hematoxylin&eosin(HE)staining and immunohistochemistry(IHC)analysis were performed.IL-1β stimulated C28/I2 cells were used as OA-like chondrocyte cell model.Western blotting assays were used to determine the protein expression.Results:The expression of MMP-13 was upregulated while type Ⅱ collagen expression is downregulated,and the phosphorylation level of STAT3 is increased in rat OA models.TMF reverses the STAT3-mediated expression of MMP-13 and type v collagen.Activation of STAT3 or inhibition of Sirt1 function attenuates the inhibitory effect of TMF on ECM degradation.Conclusion:TMF can inhibit ECM degradation mediated by the STAT3 signal pathway by activating Sirt1 expression in OA cell and animal models.展开更多
Poly(butylene adipate-terephthalate)(PBAT),as one of the most common and promising biodegradable plastics,has been widely used in agriculture,packaging,and other industries due to its strong biodegradability propertie...Poly(butylene adipate-terephthalate)(PBAT),as one of the most common and promising biodegradable plastics,has been widely used in agriculture,packaging,and other industries due to its strong biodegradability properties.It is well known that PBAT suffers a series of natural weathering,mechanical wear,hydrolysis,photochemical transformation,and other abiotic degradation processes before being biodegraded.Therefore,it is particularly important to understand the role of abiotic degradation in the life cycle of PBAT.Since the abiotic degradation of PBAT has not been systematically summarized,this review aims to summarize the mechanisms and main factors of the three major abiotic degradation pathways(hydrolysis,photochemical transformation,and thermochemical degradation)of PBAT.It was found that all of them preferentially destroy the chemical bonds with higher energy(especially C-O and C=O)of PBAT,which eventually leads to the shortening of the polymer chain and then leads to reduction in molecular weight.The main factors affecting these abiotic degradations are closely related to the energy or PBAT structure.These findings provide important theoretical and practical guidance for identifying effective methods for PBAT waste management and proposing advanced schemes to regulate the degradation rate of PBAT.展开更多
Exploration of stable metal single-site supported porous graphitic carbon nitride(PCN)nanostructures and the development of maximum atom utilization for enhanced photocatalytic oxidation of antibiotics remains a chall...Exploration of stable metal single-site supported porous graphitic carbon nitride(PCN)nanostructures and the development of maximum atom utilization for enhanced photocatalytic oxidation of antibiotics remains a challenge in current research.This work proposed a one-step thermal copolymerization to obtain Cu(Ⅰ)doping porous carbon nitride(CUCN)through a spontaneously reducing atmosphere by urea in a covered crucible.The obtained CUCN had crumpled ultrathin nanosheets and mesoporous structures,which possessed higher specific surface areas than PCN.From X-ray absorption near edge structure(XANES)and Fourier transform extended X-ray absorption fine structure(FT-EXAFS)spectra analysis,the Cu doping existed in the oxidation state of Cu(Ⅰ)as single atoms anchored on the 2D layers of CN through two N neighbors,thereby facilitating efficient pathways for the transfer of photoexcited charge carriers.Furthermore,the photoluminescence(PL)spectra,electrochemical impedance spectra(EIS)and transient photocurrent response test proved the improved separation and transfer of photoexcited charge carriers for Cu(Ⅰ)introduction.Consequently,the photocatalytic activity of CUCN was much better than that of PCN for antibiotics norfloxacin(NOR),with 4.7-fold higher degradation reaction rate constants.From species-trapping experiments and density function theory(DFT)calculations,the Cu single atoms in Cu-N_(2)served as catalytic sites that could accelerate charge transfer and facilitate the adsorption of molecular oxygen to produce active species.The stable Cu(Ⅰ)embedded in the layer structure led to the excellent recycling test and remained stable after four runs of degradation and even thermal regenerated treatment.The degradation paths of NOR by CUCN under visible light were also demonstrated.Our work sheds light on a sustainable and practical approach for achieving stable metal single-atom doping and enhancing photocatalytic degradation of aqueous pollutants.展开更多
Dissolved organic matter(DOM)is very important in aquatic environments,yet it is challenging to characterize DOM as a highly complex mixture of thousands of molecules,and the knowledge of the effects of different degr...Dissolved organic matter(DOM)is very important in aquatic environments,yet it is challenging to characterize DOM as a highly complex mixture of thousands of molecules,and the knowledge of the effects of different degradation processes on different molecules remains limited.This study examined the distribution and degradation of DOM in a large subtropical river using optical techniques and Fourier transform ion cyclotron resonance mass spectrometry(FT-ICR-MS).At the molecular level,DOM was mainly composed of CHO and lignin-like compounds,which was related to the dominance of forestland in the watershed and resulted in a low biological lability index(MLBL).The modified aromaticity index(AI_(mod)),unsaturation degree(DBE),and humic content(HIX)decreased while MLBL,H/C,absorption spectral slope(S_(275–295)),and biological index(BIX)increased in the estuarine zone due to the increasing autochthonous contribution.Photo-and microbial degradation resulted in a similar decrease in the bulk dissolved organic carbon,while they showed opposite effects on the DOM composition.Photo-degradation removed all fluorescent components and decreased molecular weight,HIX,AI_(mod),DBE,%CHO,%lignin-like,%tannin-like,and%condensed aromatic-like compounds.In contrast,bio-degradation preferentially consumed lipid-like,protein-like,and carbohydrate-like compounds,with increases in%ligninlike,%tannin-like,%condensed aromatic-like compounds,and humic-like fluorescent components.Overall,the application of ultra-high resolutionmass spectrometry provided valuable insights into the composition and behavior of DOM at themolecular level and revealed the contrasting effects of photo-and microbial degradation on different compounds.These results have implications for better understanding the composition and transformation of aquatic DOM.展开更多
The selection of carbon sources and the biosynthesis of polyhydroxybutyrate(PHB)by the Azotobacter vinelandii N-15 strain using renewable raw materials were investigated.Among the tested substrates(starch,sucrose,mola...The selection of carbon sources and the biosynthesis of polyhydroxybutyrate(PHB)by the Azotobacter vinelandii N-15 strain using renewable raw materials were investigated.Among the tested substrates(starch,sucrose,molasses,bran),molasses as the carbon source yielded the highest PHB production.The maximum polymer yield(26%of dry biomass)was achieved at a molasses concentration of 40 g/L.PHB formation was confirmed via thinlayer chromatography,gas chromatography and Fourier transform infrared spectroscopy.Composite films based on PHB,polylactic acid(PLA),and their blends were fabricated using the solvent casting.The biodegradation of these films was studied with bacteria isolated from plastic-contaminated soil.These bacteria utilized the biopolymers as their sole carbon source,with the biodegradation process lasting three months.Structural and chemical changes in the films were analyzed using FTIR spectroscopy,differential scanning calorimetry,and thermogravimetry.Among the microorganisms used to study the biodegradation of PHB,PLA,and their blends,Streptomyces sp.K2 and Streptomyces sp.K4 exhibited the highest biodegradation efficiency.PHB-containing films demonstrated significant advantages over other biodegradable polymers,as they degrade under aerobic conditions via enzymatic hydrolysis using microbial depolymerases.展开更多
This paper presents a multi-scale experimental investigation of the weathering degradation of red mudstone.Natural rocks were extracted from the surface ground to 120 m,inwhich three sets of samples were selected to c...This paper presents a multi-scale experimental investigation of the weathering degradation of red mudstone.Natural rocks were extracted from the surface ground to 120 m,inwhich three sets of samples were selected to consider the different initial rock fabrics.The long-term relative humidity(RH)cycles under two amplitudes were imposed on red mudstone to simulate the weathering process.After RH cycles,a series of uniaxial compression tests,Brazilian splitting tests and bender-extender element tests were carried out to examine the reduction in strength and stiffness.The objective of this study is to develop an extended stress-volume framework characterizing the degradation of natural red mudstone both at microscale and macroscale.Accompanied by the irreversible swelling of the rock specimen is the progressive degradation of strength,stiffness and Poisson's ratio.A unified exponential degradation model in terms of the irreversible volumetric strain was thus proposed to capture such a degradation pattern.The effect of the initial rock fabric was evident.The highest degradation rate and potential were identified in slightly weathered specimens.Significant slaking of aggregates and crack propagation were confirmed by scanning electron microscope(SEM)micrographs,which were considered as the main consequence of structure damage leading to degradation of mechanical properties.The structure damage during RH cycles denoted the hysteresis nature in the response to the cycling hydraulic reaction,in turn causing the increase in volumetric strain.Thus,the stress-volume relation rather than the suction relation was found in more reasonable agreement with the experimental results.展开更多
Wide bandgap semiconductors are typically activated under ultraviolet(UV)light irradiation for volatile organic compounds(VOCs)degradation.However,our previous study discovered that certain VOCs can interact with some...Wide bandgap semiconductors are typically activated under ultraviolet(UV)light irradiation for volatile organic compounds(VOCs)degradation.However,our previous study discovered that certain VOCs can interact with some wide bandgap semiconductors,formatting an intermediate bandgap between the VOCs and the conduction band of wide bandgap semiconductor,thus inducing visible light activation of the system,and photo-generated electrons are excited by visible light and transferred from the VOCs to the conduction band of semiconductor.In this work,BaTiO_(3),traditionally is not active under visible light irradiation,however showed degradation rates of 100%and 20%for styrene and toluene under visible light,respectively.Density functional theory(DFT)calculations indicate that the adsorption of styrene or toluene on the BaTiO_(3)surface reduces its bandgap from 2.93 eV to 1.36 eV and 2.26 eV,respectively.The intermediate bandgap in this system is primarily formed by the valence band of BaTiO_(3)and the VOCs,and indicating that photo-generated electrons directly transfer from BaTiO_(3)to the VOCs under visible light,inducing degradation reactions of VOCs,i.e.,this work discovered a new transfer pathway of photo-electrons direct from the valence band of BaTiO_(3)to VOCs,while photo-electrons are from VOCs to the conductive band of wide-bandgap semiconductors in our previous work.展开更多
Nicotine,also known as nicotinic norephedrine,is one of the main alkaloids present in tobacco plants.In recent years,due to the increase in tobacco production and smoking population,the environmental and health issues...Nicotine,also known as nicotinic norephedrine,is one of the main alkaloids present in tobacco plants.In recent years,due to the increase in tobacco production and smoking population,the environmental and health issues caused by nicotine have become increasingly severe.Traditional methods have proven ineffective in efficiently degrading residual nicotine.To address this issue,scientists both domestically and internationally have turned to biodegradation methods to tackle the environmental and health problems caused by residual nicotine.In this study,an enrichment method was used to screen bacteria with nicotine-degrading capabilities from the soil of tobacco planting sites at the Tobacco Research Institute of Heilongjiang in Bin County,Harbin City.Through phenotypic observations and 16S rDNA identification,a bacterial strain identified as Pseudomonas hunanensis MGJ-2 was isolated,capable of utilizing nicotine as a carbon and nitrogen source for growth.High-performance liquid chromatography(HPLC)-1 analysis revealed that within 25 h,strain MGJ-2 could degrade nicotine 500 mg·L^(-1) with an efficiency exceeding 99.9%.Strain MGJ-2 was applied to tobacco,and after 15 days of incubation and fermentation,it degraded 10.57%of nicotine in tobacco.Overall,the discovery of strain MGJ-2 enriched the resources of nicotine-degrading strains.Its remarkable biodegradation performance held immense potential for future biodegradation of nicotine in tobacco.展开更多
BACKGROUND Gastric cancer(GC)is a prevalent malignancy with a substantial health burden and high mortality rate,despite advances in prevention,early detection,and treatment.Compared with the global average,Asia,notabl...BACKGROUND Gastric cancer(GC)is a prevalent malignancy with a substantial health burden and high mortality rate,despite advances in prevention,early detection,and treatment.Compared with the global average,Asia,notably China,reports disproportionately high GC incidences.The disease often progresses asymptoma-tically in the early stages,leading to delayed diagnosis and compromised out-comes.Thus,it is crucial to identify early diagnostic biomarkers and enhance treatment strategies to improve patient outcomes and reduce mortality.METHODS Retrospectively analyzed the clinical data of 148 patients with GC treated at the Civil Aviation Shanghai Hospital between December 2022 and December 2023.The associations of coagulation indices-partial thromboplastin time(APTT),prothrombin time(PT),thrombin time(TT),fibrinogen,fibrinogen degradation products(FDP),fasting blood glucose,and D-dimer(D-D)with TNM stage and distant metastasis were examined.RESULTS Prolongation of APTT,PT,and TT was significantly correlated with the GC TNM stage.Hence,abnormal coagulation system activation was closely related to disease progression.Elevated FDP and D-D were significantly associated with distant metastasis in GC(P<0.05),suggesting that increased fibrinolytic activity contributes to increased metastatic risk.CONCLUSION Our Results reveal coagulation indices,FDPs as GC biomarkers,reflecting abnormal coagulation/fibrinolysis,aiding disease progression,metastasis prediction,and helping clinicians assess thrombotic risk for early intervention and personalized treatment plans.展开更多
With the approaching of large-scale retirement of power lithium-ion batteries(LIBs),their urgent handling is required for environmental protection and resource reutilization.However,at present,substantial spent power ...With the approaching of large-scale retirement of power lithium-ion batteries(LIBs),their urgent handling is required for environmental protection and resource reutilization.However,at present,substantial spent power batteries,especially for those high recovery value cathode materials,have not been greenly,sustainably,and efficiently recycled.Compared to the traditional recovery method for cathode materials with high energy consumption and severe secondary pollution,the direct repair regeneration,as a new type of short-process and efficient treatment methods,has attracted widespread attention.However,it still faces challenges in homogenization repair,electrochemical performance decline,and scaling-up production.To promote the direct regeneration technology development of failed NCM materials,herein we deeply discuss the failure mechanism of nickel-cobalt-manganese(NCM)ternary cathode materials,including element loss,Li/Ni mixing,phase transformation,structural defects,oxygen release,and surface degradation and reconstruction.Based on this,the detailed analysis and summary of the direct regeneration method embracing solid-phase sintering,eutectic salt assistance,solvothermal synthesis,sol-gel process,spray drying,and redox mediation are provided.Further,the upcycling strategy for regeneration materials,such as single-crystallization and high-nickelization,structural regulation,ion doping,and surface engineering,are discussed in deep.Finally,the challenges faced by the direct regeneration and corresponding countermeasures are pointed out.Undoubtedly,this review provides valuable guidance for the efficient and high-value recovery of failed cathode materials.展开更多
基金supported by the Bingtuan Industrial Technology Research Institute,Bingtuan New materials Research Institute innovation platform project,Research initiation project of Shihezi University(No.RCZK202330)the Science and Technology Program-Regional Innovation Guidance Program(No.2023ZD080)Tianchi Talent Project(No.CZ002735).
文摘The microbial degradation of aromatic organic pollutants is incomplete due to their metabolic characteristics,which can easily produce certain highly toxic intermediates.Therefore,this article designs a dual template molec-ularly imprinted sensor(DTMIP/Fe-Mn@C)for iron manganese metal nanomaterials,prepared Fe-Mn@C com-posite materials by a one pot method were coated on the surface of glassy carbon electrodes and covered with molecularly imprinted membranes through electropolymerization and elution methods,achieving real-time de-tection of specific intermediate products 2-methylbutyric acid(2-MBA)and 3-methylbutyric acid(3-MBA)de-graded by azo dyes.In order to determine the detection sensitivity and intensity range of the sensor,optimization experiments were conducted on various parameters that affect the detection performance,such as the type of func-tional monomer and its composition ratio with the template molecule,detection time window,environmental pH value,etc.Finally,o-Phenylenediamine was determined as the functional monomer,with a molar ratio of 1:1:6 to the template molecules 2-MBA and 3-MBA.Electrochemical testing was conducted in a neutral environment with an incubation time of 5 min and pH=7.The results indicate that the sensor has a relatively wide detection range,high sensitivity,obvious recognition features,and excellent stability for 2-MBA and 3-MBA.This new dual template molecularly imprinted sensor can quickly and accurately determine the safety of highly toxic interme-diates in the degradation process of aromatic organic pollutants,providing a theoretical basis and application potential for trace detection and real-time monitoring.
基金supported by the Youth Talent Project of China Nuclear Power Engineering Co.,Ltd.(KY24045).
文摘While nuclear energy represents a low-carbon and high-efficiency energy source that plays a vital role in the global energy mix,the limitations of spent fuel reprocessing technology pose a major challenge to its sustainable development.The PUREX(plutonium uranium redox extraction)process is currently the dominant nuclear fuel reprocessing technology in the world.However,the key extractant in this process is tributyl phosphate(TBP),which degrades under intense radiation,high temperatures,and strong acidity.This leads to the production of dibutyl phosphate,monobutyl phosphate,and other degradation byproducts,which may reduce the extraction efficiency and trigger third-phase formation and equipment corrosion.This paper systematically reviews the degradation mechanisms of TBP and its diluents,the analytical technique suitable for characterizing degradation products,and the impact of degradation products on the post-treatment process.Additionally,optimization strategies employed for suppressing third-phase formation are discussed.This study offers a theoretical foundation and technical insights in optimizing the PUREX process and ensuring the safe operation of the post-treatment process.
文摘The escalating pace of industrialization has significantly intensified water pollution challenges,for instance,the persistent organic pollutants like methyl orange(MO).Conventional remediation techniques,such as adsorption and biological degradation,are often hampered by low efficiency and the risk of secondary pollution.Photocatalysis emerges as a promising sustainable alternative;however,the benchmark material titanium dioxide(TiO_(2))suffers from its intrinsic limitations,notably its wide bandgap energy(≥3.4 eV)restricting its activity to the region of the ultraviolet light and its rapid recombination of photogenerated charge carriers.To overcome these constraints,this research focused on synthesizing novel TiO_(2)/Sn_(3)O_(4) heterojunction composite photocatalysts via a solvothermal approach.Comprehensive characterization techniques confirmed the successful formation of the composite,which revealed that ultrathin Sn3O4 nanosheets uniformly coated TiO_(2) nanospheres.This unique architecture effectively reduced the overall crystallinity and introduced the beneficial oxygen vacancies.Under visible-light irradiation(λ≥420 nm),the optimized TiO_(2)/Sn3O4 composite exhibited the exceptional photocatalytic performance,which achieved 96%degradation of MO within just 60 minutes.The calculated apparent kinetic rate constant(0.103 min^(-1))was remarkably(5.15 times)higher than that of pristine TiO_(2).ESR experiments identified that hydroxyl radicals(·OH)was the predominant active species driving the degradation.Furthermore,cyclic degradation tests demonstrated its excellent material stability,with the composite retaining 85%of its initial efficiency after four consecutive reuse cycles.This work underscored the synergistic effects within the TiO_(2)/Sn_(3)O_(4) heterojunction,which significantly enhanced the visible-light absorption,charge separation,and photocatalytic activity,which provided the valuable insights for designing efficient,stable catalysts for the advanced environmental remediation applications.
基金financially supported by the National Natural Science Foundation of China (No.52100076)the Fundamental Research Funds for the Central Universities (No.2023MS064)。
文摘The escalating global issues of water scarcity and pollution emphasize the critical need for the rapid development of efficient and eco-friendly water treatment technologies.Photoelectrocatalytic technology has emerged as a promising solution for effectively degrading refractory organic pollutants in water under light conditions.This review delves into the advancements made in the field,focusing on strategies to enhance the generation of active species by modulating the micro-interface of the photoanode.Strategies,such as morphological control,element doping,introduction of surface oxygen vacancies,and construction of heterostructures,significantly improve the separation efficiency of photogenerated charges and the generation of active species,thereby boosting the efficiency of photoelectrocatalytic performance.Furthermore,the review explores the potential applications of photoelectrocatalytic technology in organic pollutant degradation in solutions.It also outlines the current challenges and future development directions.Despite its remarkable laboratory success,practical implementation of photoelectrocatalytic technology encounters obstacles related to stability,cost-effectiveness,and operational efficiency.Future investigations need to focus on optimizing the performance of photoelectrocatalytic materials and exploring strategies for upscaling their application in real water treatment scenarios.
基金supported by the grants PID2020-113371RA-C22 and TED2021-130845A-C32,funded by MCIN/AEI/10.13039/501100011033.M.Marín-García,R.González-OlmosC.Gómez-Canela are members of the GESPA group(Grup d’Enginyeria i Simulacióde Processos Ambientals)at IQS-URL,which has been acknowledged as a Consolidated Research Group by the Government of Catalonia(No.2021-SGR-00321)+1 种基金In addition,M.Marín-García has been awarded a public grant for the Investigo Programme,aimed at hiring young job seekers to undertake research and innovation projects under the Recovery,Transformation,and Resilience Plan(PRTR),European Union Next Generation,for the year 2022,through the Government of Catalonia and the Spanish Ministry for Work and Social Economy(No.100045ID16)Ana Belén Cuenca for her support and expertise,which helped to confirm the proposed reaction mechanism involved in the UV photolysis of cloperastine.
文摘The increasing production and release of synthetic organic chemicals,including pharmaceuticals,into our envi-ronment has allowed these substances to accumulate in our surface water systems.Current purification technolo-gies have been unable to eliminate these pollutants,resulting in their ongoing release into aquatic ecosystems.This study focuses on cloperastine(CPS),a cough suppressant and antihistamine medication.The environmental impact of CPS usage has become a concern,mainly due to its increased detection during the COVID-19 pandemic.CPS has been found in wastewater treatment facilities,effluents from senior living residences,river waters,and sewage sludge.However,the photosensitivity of CPS and its photodegradation profile remain largely unknown.This study investigates the photodegradation process of CPS under simulated tertiary treatment conditions using UV photolysis,a method commonly applied in some wastewater treatment plants.Several transformation prod-ucts were identified,evaluating their kinetic profiles using chemometric approaches(i.e.,curve fitting and the hard-soft multivariate curve resolution-alternating least squares(HS-MCR-ALS)algorithm)and calculating the reaction quantum yield.As a result,three different transformation products have been detected and correctly identified.In addition,a comprehensive description of the kinetic pathway involved in the photodegradation process of the CPS drug has been provided,including observed kinetic rate constants.
基金supported by the National Natural Science Foundation of China(Nos.42477406 and 51878617)the Horizontal Scientific Research Project(No.KYY-HX-20220803)the Engineering Research Center of Ministry of Education for Renewable Energy Infrastructure Construction Technology.
文摘In this work,we constructed a three-dimensional electrochemical system(3D-ECO),which included the cathode and anode electrode plates,as well as the screening of three-dimensional particle electrodes and parameter opti-mization,for the degradation of landfill leachate(LL)containing elevated levels of tetracycline(TC),and explored its mechanism of action.Firstly,titanium-based ruthenium-iridium(Ti/RuO_(2)-IrO_(2)),titanium-based ruthenium-iridium-platinum(Ti/Pt-RuO_(2)-IrO_(2)),and titanium-based tin-antimony(Ti/SnO_(2)-Sb_(2)O_(3))were employed as an-odes in the electrocatalytic oxidation system,with titanium and stainless steel plates serving as cathodes,to construct the optimal two-dimensional electrocatalytic oxidation system(2D-ECO)through cross-comparison ex-periments.Subsequently,using granular activated carbon(GAC),coconut shell biochar(CBC),walnut shell carbon(WBC),and bamboo charcoal(BBC)as particle electrodes,a 3D-ECO system was developed.The influence of var-ious operational parameters on treating TC-containing LL was investigated.The optimal operating parameters obtained from the study was:pH=5,current density of 30 mA/cm^(2),particle dosage of 7 g/L,particle size ranging from 1.70 to 2.00 mm,and electrode spacing of 4 cm.Under these conditions,the COD removal rate of 3D-ECO within three hours was 90.25%,the TC removal rate was 72.41%,and the NH_(3)-N removal rate was 39.52%.The removal of TC followed a pseudo-first-order kinetic model.Additionally,degradation mechanisms were elucidated through electron paramagnetic resonance(EPR)spectrometer and Tert-Butanol(TBA)quenching experiments,indicating that the degradation primarily occurred through a non-radical(1O_(2))pathway.This re-search offers a comprehensive analysis of the simultaneous breakdown of intricate LL matrices and TC,enhancing our comprehension of the degradation processes and underlying mechanisms.
基金supported byHainan Provincial Natural Science Foundation of China(Nos.422RC600,519QN175)National Natural Science Foundation ofChina(Nos.52160018,21801053,52400206,52500209)High-Level Talent Program of Hainan Province(Nos.XJ2400008202,XJ2400011473).
文摘Oxidative magnetization has attracted great attention as an efficient strategy for modulating physiochemical properties of magnetic biochar.In this paper,a K_(2)FeO_(4)-involving hydrothermal oxidative magnetization was explored to regulate multiple micro-structures for manufacture magnetic hydrochar(MHC)for Fenton-like degradation of tetracycline in aqueous solution.Diverse shapes of Fe_(3)O_(4) and nano zero-valent iron(nZVI)were doped with abundant oxygen containing groups and persistent free radicals(PFRs).Multiple catalysis sites including iron species,PFRs,oxygen containing groups,and graphite defects contributed to accelerate the Fenton-like degradation with synergistic effect.Notably,MHC achieved a tetracycline removal rate of 99% within 60 min at 50 mg/L,with a total organic carbon(TOC)removal rate of 35%.Furthermore,after four cycles of reuse,the degradation efficiency slightly decreased to 93%.This study highlights the potential of magnetic hydrochar with multiple catalytic sites in the effective and sustainable degradation of pollutants.
基金Motor Neuron Disease Research Australia in the form of a Bill Gole Postdoctoral Fellowship(PDF2307)FightMND in the form of Drug Development Grants(DDG-159 and DDG137 to JSL)。
文摘Superoxide dismutase 1(SOD1)is a thermodynamically stable,zinc and copper binding homodimeric enzyme responsible for breaking down superoxide radicals.More than 200,mostly missense,mutations spread throughout the SOD1 gene are associated with the fatal neurodegenerative disease,amyotrophic lateral sclerosis(ALS).A unifying feature of ALS-associated SOD1 mutations is the destabilization of the SOD1 protein structure,increasing the propensity for misfolding and subsequent pathological aggregation.Post-mortem analysis of SOD1-associated ALS tissue shows the accumulation of misfolded SOD1 protein and ubiquitinated SOD1 inclusions within motor neurons.Misfolded SOD1 accumulation and aggregates are implicated in cellular dysfunction via a number of disparate but critical processes,including endoplasmic reticulum stress,oxidative damage,proteasome dysfunction,axonal transport abnormalities and synaptic dysfunction;culminating in motor neuron degeneration associated with ALS.
基金supported by the National Natural Science Foundation of China (No.52370174)the Natural Science Foundation of Shandong Province,China (No.ZR2022ME128)Special Projects in Key Areas of Colleges and Universities in Guangdong Province (No.2023ZDZX4050)。
文摘The excessive use of pesticides has exacerbated environmental pollution due to herbicide residues,while their persistent toxicity poses serious challenges to global ecological security.A magnetically recyclable CoFe_(2)O_(4)/BiOBr S-scheme heterojunctions was prepared by microwave-assisted co-precipitation method for photocatalytic degradation of Diuron(DUR) in water.The formation of S-scheme heterojunction enhances electron transfer and charge separation,which was demonstrated by free radical trapping,electrochemical experiments,and DFT calculations.The magnetic CoFe_(2)O_(4)/BiOBr catalysts can achieve 99.9 %removal of diuron in 50 min under visible light irradiation.Furthermore,the system maintains stable performance across a broad p H range(3-9),enabling adaptation to diverse water environments,effective elimination of multiple pollutants,and strong resistance to ionic interference.Using magnetic recovery,CoFe_(2)O_(4)/BiOBr exhibits a high removal rate of 99 % and a markedly low ion leaching rate(<20 μg/L) after six cycles photocatalytic process,confirming its excellent stability and durability.According to HPLCQTOF-MS and DFT calculation,the main ways of DUR degradation include dechlorinated hydroxylation,dealkylation and hydroxylation of aromatic ring and side chain.Toxicity analysis showed that the toxicity of the intermediates generated during degradation was generally lower than that of DUR.The magnetic CoFe_(2)O_(4)/BiOBr S-scheme heterojunction developed in this study exhibits excellent photocatalytic performance,high applicability,good stability,and durability,providing an effective magnetic for the removal of refractory pollutants.
基金supported by the Jiangsu Engineering Research Center of the Key Technology for Intelligent Manufacturing Equipment and the Suqian Key Laboratory of Intelligent Manufacturing(Grant No.M202108).
文摘To address the issues of insufficient and imbalanced data samples in proton exchange membrane fuel cell(PEMFC)performance degradation prediction,this study proposes a data augmentation-based model to predict PEMFC performance degradation.Firstly,an improved generative adversarial network(IGAN)with adaptive gradient penalty coefficient is proposed to address the problems of excessively fast gradient descent and insufficient diversity of generated samples.Then,the IGANis used to generate datawith a distribution analogous to real data,therebymitigating the insufficiency and imbalance of original PEMFC samples and providing the predictionmodel with training data rich in feature information.Finally,a convolutional neural network-bidirectional long short-termmemory(CNN-BiLSTM)model is adopted to predict PEMFC performance degradation.Experimental results show that the data generated by the proposed IGAN exhibits higher quality than that generated by the original GAN,and can fully characterize and enrich the original data’s features.Using the augmented data,the prediction accuracy of the CNN-BiLSTM model is significantly improved,rendering it applicable to tasks of predicting PEMFC performance degradation.
基金Project Supported by Jiangxi Provincial Natural Science Foundation(20212ACB206002)。
文摘Objective:Osteoarthritis(OA)is a degenerative joint disease characterized by extracellular matrix(ECM)degradation,chondrocyte apoptosis,and chronic inflammation.Cartilage destruction and ECM degeneration contribute to joint function loss and disability.Signal transducer and activator of transcription 3(STAT3)up-regulates the expression of MMP-13,which degrades collagen Ⅱ.Our previous study found that 5,7,3',4'-tetramethoxyflavone(TMF)exhibited protective effects on OA chondrocytes.This study aims to investigate the protective role of TMF in inhibiting ECM degradation by mediating the Sirt1/STAT3 signaling pathway.Methods:Rat OA models were established by the injection of monosodium iodoacetate(MIA).Hematoxylin&eosin(HE)staining and immunohistochemistry(IHC)analysis were performed.IL-1β stimulated C28/I2 cells were used as OA-like chondrocyte cell model.Western blotting assays were used to determine the protein expression.Results:The expression of MMP-13 was upregulated while type Ⅱ collagen expression is downregulated,and the phosphorylation level of STAT3 is increased in rat OA models.TMF reverses the STAT3-mediated expression of MMP-13 and type v collagen.Activation of STAT3 or inhibition of Sirt1 function attenuates the inhibitory effect of TMF on ECM degradation.Conclusion:TMF can inhibit ECM degradation mediated by the STAT3 signal pathway by activating Sirt1 expression in OA cell and animal models.
基金supported by the National Key R&D Program of China(No.2022YFC3901800)the National Natural Science Foundation of China(No.22176041)Guangzhou Science and Technology Planning Project(No.2023A04J0918)。
文摘Poly(butylene adipate-terephthalate)(PBAT),as one of the most common and promising biodegradable plastics,has been widely used in agriculture,packaging,and other industries due to its strong biodegradability properties.It is well known that PBAT suffers a series of natural weathering,mechanical wear,hydrolysis,photochemical transformation,and other abiotic degradation processes before being biodegraded.Therefore,it is particularly important to understand the role of abiotic degradation in the life cycle of PBAT.Since the abiotic degradation of PBAT has not been systematically summarized,this review aims to summarize the mechanisms and main factors of the three major abiotic degradation pathways(hydrolysis,photochemical transformation,and thermochemical degradation)of PBAT.It was found that all of them preferentially destroy the chemical bonds with higher energy(especially C-O and C=O)of PBAT,which eventually leads to the shortening of the polymer chain and then leads to reduction in molecular weight.The main factors affecting these abiotic degradations are closely related to the energy or PBAT structure.These findings provide important theoretical and practical guidance for identifying effective methods for PBAT waste management and proposing advanced schemes to regulate the degradation rate of PBAT.
基金supported by the National Natural Science Foundation of China(Nos.52070103 and 22102102)Zhejiang Provincial Natural Science Foundation of China(Nos.LY21E090004 and LQ22B050004)+1 种基金Ningbo Public Welfare Science and Technology Program(No.2021S025)Ningbo Youth Leading Talent Project(No.2024QL038).
文摘Exploration of stable metal single-site supported porous graphitic carbon nitride(PCN)nanostructures and the development of maximum atom utilization for enhanced photocatalytic oxidation of antibiotics remains a challenge in current research.This work proposed a one-step thermal copolymerization to obtain Cu(Ⅰ)doping porous carbon nitride(CUCN)through a spontaneously reducing atmosphere by urea in a covered crucible.The obtained CUCN had crumpled ultrathin nanosheets and mesoporous structures,which possessed higher specific surface areas than PCN.From X-ray absorption near edge structure(XANES)and Fourier transform extended X-ray absorption fine structure(FT-EXAFS)spectra analysis,the Cu doping existed in the oxidation state of Cu(Ⅰ)as single atoms anchored on the 2D layers of CN through two N neighbors,thereby facilitating efficient pathways for the transfer of photoexcited charge carriers.Furthermore,the photoluminescence(PL)spectra,electrochemical impedance spectra(EIS)and transient photocurrent response test proved the improved separation and transfer of photoexcited charge carriers for Cu(Ⅰ)introduction.Consequently,the photocatalytic activity of CUCN was much better than that of PCN for antibiotics norfloxacin(NOR),with 4.7-fold higher degradation reaction rate constants.From species-trapping experiments and density function theory(DFT)calculations,the Cu single atoms in Cu-N_(2)served as catalytic sites that could accelerate charge transfer and facilitate the adsorption of molecular oxygen to produce active species.The stable Cu(Ⅰ)embedded in the layer structure led to the excellent recycling test and remained stable after four runs of degradation and even thermal regenerated treatment.The degradation paths of NOR by CUCN under visible light were also demonstrated.Our work sheds light on a sustainable and practical approach for achieving stable metal single-atom doping and enhancing photocatalytic degradation of aqueous pollutants.
基金supported by Fujian Provincial Natural Science Foundation of China(Nos.2023J01456 and 2021J01626)the National Natural Science Foundation of China(No.41976042)the Oceanic Interdisciplinary Program of Shanghai Jiao Tong University(Nos.SL2022ZD207 and SL2023MS019).
文摘Dissolved organic matter(DOM)is very important in aquatic environments,yet it is challenging to characterize DOM as a highly complex mixture of thousands of molecules,and the knowledge of the effects of different degradation processes on different molecules remains limited.This study examined the distribution and degradation of DOM in a large subtropical river using optical techniques and Fourier transform ion cyclotron resonance mass spectrometry(FT-ICR-MS).At the molecular level,DOM was mainly composed of CHO and lignin-like compounds,which was related to the dominance of forestland in the watershed and resulted in a low biological lability index(MLBL).The modified aromaticity index(AI_(mod)),unsaturation degree(DBE),and humic content(HIX)decreased while MLBL,H/C,absorption spectral slope(S_(275–295)),and biological index(BIX)increased in the estuarine zone due to the increasing autochthonous contribution.Photo-and microbial degradation resulted in a similar decrease in the bulk dissolved organic carbon,while they showed opposite effects on the DOM composition.Photo-degradation removed all fluorescent components and decreased molecular weight,HIX,AI_(mod),DBE,%CHO,%lignin-like,%tannin-like,and%condensed aromatic-like compounds.In contrast,bio-degradation preferentially consumed lipid-like,protein-like,and carbohydrate-like compounds,with increases in%ligninlike,%tannin-like,%condensed aromatic-like compounds,and humic-like fluorescent components.Overall,the application of ultra-high resolutionmass spectrometry provided valuable insights into the composition and behavior of DOM at themolecular level and revealed the contrasting effects of photo-and microbial degradation on different compounds.These results have implications for better understanding the composition and transformation of aquatic DOM.
基金financial support of this paper by the Ministry of Education and Science of Ukraine under grant(Biotherm/0124U000789).
文摘The selection of carbon sources and the biosynthesis of polyhydroxybutyrate(PHB)by the Azotobacter vinelandii N-15 strain using renewable raw materials were investigated.Among the tested substrates(starch,sucrose,molasses,bran),molasses as the carbon source yielded the highest PHB production.The maximum polymer yield(26%of dry biomass)was achieved at a molasses concentration of 40 g/L.PHB formation was confirmed via thinlayer chromatography,gas chromatography and Fourier transform infrared spectroscopy.Composite films based on PHB,polylactic acid(PLA),and their blends were fabricated using the solvent casting.The biodegradation of these films was studied with bacteria isolated from plastic-contaminated soil.These bacteria utilized the biopolymers as their sole carbon source,with the biodegradation process lasting three months.Structural and chemical changes in the films were analyzed using FTIR spectroscopy,differential scanning calorimetry,and thermogravimetry.Among the microorganisms used to study the biodegradation of PHB,PLA,and their blends,Streptomyces sp.K2 and Streptomyces sp.K4 exhibited the highest biodegradation efficiency.PHB-containing films demonstrated significant advantages over other biodegradable polymers,as they degrade under aerobic conditions via enzymatic hydrolysis using microbial depolymerases.
基金The financial support from Project(Grant Nos.52278432,and 52168066)of National Natural Science Foundation of China and Project(Grant No.K2023G033)of the Science and Technology Research and Development Plan of China National Railway Group Co.,Ltd.were greatly appreciated.
文摘This paper presents a multi-scale experimental investigation of the weathering degradation of red mudstone.Natural rocks were extracted from the surface ground to 120 m,inwhich three sets of samples were selected to consider the different initial rock fabrics.The long-term relative humidity(RH)cycles under two amplitudes were imposed on red mudstone to simulate the weathering process.After RH cycles,a series of uniaxial compression tests,Brazilian splitting tests and bender-extender element tests were carried out to examine the reduction in strength and stiffness.The objective of this study is to develop an extended stress-volume framework characterizing the degradation of natural red mudstone both at microscale and macroscale.Accompanied by the irreversible swelling of the rock specimen is the progressive degradation of strength,stiffness and Poisson's ratio.A unified exponential degradation model in terms of the irreversible volumetric strain was thus proposed to capture such a degradation pattern.The effect of the initial rock fabric was evident.The highest degradation rate and potential were identified in slightly weathered specimens.Significant slaking of aggregates and crack propagation were confirmed by scanning electron microscope(SEM)micrographs,which were considered as the main consequence of structure damage leading to degradation of mechanical properties.The structure damage during RH cycles denoted the hysteresis nature in the response to the cycling hydraulic reaction,in turn causing the increase in volumetric strain.Thus,the stress-volume relation rather than the suction relation was found in more reasonable agreement with the experimental results.
基金financially supported by the National Natural Science Foundation of China(No.22176041,T2421005)National Key R&D Program of China(No.2022YFC3901800)+1 种基金the Fundamental Research Funds for the Central Universities(No.2243200011)Guangzhou Science and Technology Planning Project(No.2023A04J0918).
文摘Wide bandgap semiconductors are typically activated under ultraviolet(UV)light irradiation for volatile organic compounds(VOCs)degradation.However,our previous study discovered that certain VOCs can interact with some wide bandgap semiconductors,formatting an intermediate bandgap between the VOCs and the conduction band of wide bandgap semiconductor,thus inducing visible light activation of the system,and photo-generated electrons are excited by visible light and transferred from the VOCs to the conduction band of semiconductor.In this work,BaTiO_(3),traditionally is not active under visible light irradiation,however showed degradation rates of 100%and 20%for styrene and toluene under visible light,respectively.Density functional theory(DFT)calculations indicate that the adsorption of styrene or toluene on the BaTiO_(3)surface reduces its bandgap from 2.93 eV to 1.36 eV and 2.26 eV,respectively.The intermediate bandgap in this system is primarily formed by the valence band of BaTiO_(3)and the VOCs,and indicating that photo-generated electrons directly transfer from BaTiO_(3)to the VOCs under visible light,inducing degradation reactions of VOCs,i.e.,this work discovered a new transfer pathway of photo-electrons direct from the valence band of BaTiO_(3)to VOCs,while photo-electrons are from VOCs to the conductive band of wide-bandgap semiconductors in our previous work.
基金Supported by the Research on Biofermentation Technology of Domestic Cigar Tobacco(202115010534-JS-178)(2021)。
文摘Nicotine,also known as nicotinic norephedrine,is one of the main alkaloids present in tobacco plants.In recent years,due to the increase in tobacco production and smoking population,the environmental and health issues caused by nicotine have become increasingly severe.Traditional methods have proven ineffective in efficiently degrading residual nicotine.To address this issue,scientists both domestically and internationally have turned to biodegradation methods to tackle the environmental and health problems caused by residual nicotine.In this study,an enrichment method was used to screen bacteria with nicotine-degrading capabilities from the soil of tobacco planting sites at the Tobacco Research Institute of Heilongjiang in Bin County,Harbin City.Through phenotypic observations and 16S rDNA identification,a bacterial strain identified as Pseudomonas hunanensis MGJ-2 was isolated,capable of utilizing nicotine as a carbon and nitrogen source for growth.High-performance liquid chromatography(HPLC)-1 analysis revealed that within 25 h,strain MGJ-2 could degrade nicotine 500 mg·L^(-1) with an efficiency exceeding 99.9%.Strain MGJ-2 was applied to tobacco,and after 15 days of incubation and fermentation,it degraded 10.57%of nicotine in tobacco.Overall,the discovery of strain MGJ-2 enriched the resources of nicotine-degrading strains.Its remarkable biodegradation performance held immense potential for future biodegradation of nicotine in tobacco.
文摘BACKGROUND Gastric cancer(GC)is a prevalent malignancy with a substantial health burden and high mortality rate,despite advances in prevention,early detection,and treatment.Compared with the global average,Asia,notably China,reports disproportionately high GC incidences.The disease often progresses asymptoma-tically in the early stages,leading to delayed diagnosis and compromised out-comes.Thus,it is crucial to identify early diagnostic biomarkers and enhance treatment strategies to improve patient outcomes and reduce mortality.METHODS Retrospectively analyzed the clinical data of 148 patients with GC treated at the Civil Aviation Shanghai Hospital between December 2022 and December 2023.The associations of coagulation indices-partial thromboplastin time(APTT),prothrombin time(PT),thrombin time(TT),fibrinogen,fibrinogen degradation products(FDP),fasting blood glucose,and D-dimer(D-D)with TNM stage and distant metastasis were examined.RESULTS Prolongation of APTT,PT,and TT was significantly correlated with the GC TNM stage.Hence,abnormal coagulation system activation was closely related to disease progression.Elevated FDP and D-D were significantly associated with distant metastasis in GC(P<0.05),suggesting that increased fibrinolytic activity contributes to increased metastatic risk.CONCLUSION Our Results reveal coagulation indices,FDPs as GC biomarkers,reflecting abnormal coagulation/fibrinolysis,aiding disease progression,metastasis prediction,and helping clinicians assess thrombotic risk for early intervention and personalized treatment plans.
基金financially supported by the National Key Research and Development Program of China(2023YFB3809300)。
文摘With the approaching of large-scale retirement of power lithium-ion batteries(LIBs),their urgent handling is required for environmental protection and resource reutilization.However,at present,substantial spent power batteries,especially for those high recovery value cathode materials,have not been greenly,sustainably,and efficiently recycled.Compared to the traditional recovery method for cathode materials with high energy consumption and severe secondary pollution,the direct repair regeneration,as a new type of short-process and efficient treatment methods,has attracted widespread attention.However,it still faces challenges in homogenization repair,electrochemical performance decline,and scaling-up production.To promote the direct regeneration technology development of failed NCM materials,herein we deeply discuss the failure mechanism of nickel-cobalt-manganese(NCM)ternary cathode materials,including element loss,Li/Ni mixing,phase transformation,structural defects,oxygen release,and surface degradation and reconstruction.Based on this,the detailed analysis and summary of the direct regeneration method embracing solid-phase sintering,eutectic salt assistance,solvothermal synthesis,sol-gel process,spray drying,and redox mediation are provided.Further,the upcycling strategy for regeneration materials,such as single-crystallization and high-nickelization,structural regulation,ion doping,and surface engineering,are discussed in deep.Finally,the challenges faced by the direct regeneration and corresponding countermeasures are pointed out.Undoubtedly,this review provides valuable guidance for the efficient and high-value recovery of failed cathode materials.
