The vestibular system plays a pivotal role in maintaining body balance and postural stability[1].Its functional disruption can trigger a compensatory process termed vestibular compensation,which is fundamental to the ...The vestibular system plays a pivotal role in maintaining body balance and postural stability[1].Its functional disruption can trigger a compensatory process termed vestibular compensation,which is fundamental to the rehabilitation from various vestibular pathologies[2].This adaptive mechanism is characterized by a complex array of neural and molecular adjustments within the central nervous system[3-6].The medial vestibular nucleus(MVN)of the brainstem,is a crucial player in the vestibular compensation,acting as a central integrative hub that coordinates regulatory inputs from other brain regions involved in balance control[7].Understanding the mechanism of neurotransmissions to MVN is conducive to the development of new alternatives for the treatment of vestibular disorders.展开更多
基金supported by grants from the National Key Research and Development Program of China(2023YFC2508002,2023YFC2508403 and 2023YFC2508401)the National Natural Science Foundation of China(82371168 and 82171152)the Hubei Provincial Key Research and Development Program(2023BCB027)。
文摘The vestibular system plays a pivotal role in maintaining body balance and postural stability[1].Its functional disruption can trigger a compensatory process termed vestibular compensation,which is fundamental to the rehabilitation from various vestibular pathologies[2].This adaptive mechanism is characterized by a complex array of neural and molecular adjustments within the central nervous system[3-6].The medial vestibular nucleus(MVN)of the brainstem,is a crucial player in the vestibular compensation,acting as a central integrative hub that coordinates regulatory inputs from other brain regions involved in balance control[7].Understanding the mechanism of neurotransmissions to MVN is conducive to the development of new alternatives for the treatment of vestibular disorders.
