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Mechanisms of cancer pain and the multitarget therapeutic potential of Traditional Chinese Medicine 被引量:1
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作者 XU Guo-Qun TIAN Ying-Xin +4 位作者 SI Guang-Yi BU Xiao-Na ZHANG Min JIAO Hui-Feng PAN Hai-Li 《生理学报》 北大核心 2026年第1期16-46,共31页
Cancer pain is one of the most prevalent and debilitating symptoms in patients with advanced malignancies,arising from multifactorial mechanisms involving peripheral,central,and systemic pathways.Conventional analgesi... Cancer pain is one of the most prevalent and debilitating symptoms in patients with advanced malignancies,arising from multifactorial mechanisms involving peripheral,central,and systemic pathways.Conventional analgesics,including opioids and nonsteroidal anti-inflammatory drugs,are often limited by their insufficient efficacy,tolerance,and risk of dependence.Traditional Chinese Medicine(TCM),characterized by its multi-component,multi-target,and systemic regulatory properties,has shown promising potential in cancer pain management.This review provides a comprehensive overview of the clinical classification and underlying mechanisms of cancer pain(including nerve infiltration,dysregulation of inflammatory mediators and ion channels,central sensitization,neuro-immune crosstalk,metabolic reprogramming,and gut-brain axis impairment),as well as the analgesic effects of representative TCM agents in cancer pain management.For example,bioactive components such as tetrahydroberberine,levo-tetrahydropalmatine,and piperine exert analgesic effects,thereby improving the quality of life of patients by inhibiting inflammatory cascades,regulating neurotransmitter systems,and preserving neural integrity.Commonly used preclinical models,including bone cancer pain,pancreatic cancer pain,and chemotherapy-induced peripheral neuropathy models,are summarized for their utility in mechanistic studies and efficacy evaluations.This review also discusses the current limitations of clinical evidence,such as small sample sizes,short follow-up periods,and limited translation from animal models,alongside major challenges in standardization,mechanistic elucidation,and clinical trial design.Future directions should focus on precise pain phenotyping,integrated multi-target interventions,rigorous efficacy safety validation,and innovations in drug delivery to facilitate the standardization and global adoption of TCM in cancer pain management. 展开更多
关键词 cancer pain ANALGESICS Traditional Chinese Medicine(TCM) preclinical models bone cancer pain
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Reshaping the future of cancer therapy:taming toxicity and side effects 被引量:1
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作者 Meng-Yao Li Heng Zhang +5 位作者 Jun Li Yi-Sheng Chen Shuai Ren Wen-Long Sun Qian Zhang Gokhan Zengin 《Biomedical Engineering Communications》 2026年第2期41-49,共9页
Cancer continues to pose a formidable challenge in global health,with conventional treatments such as chemotherapy and radiotherapy often resulting in severe toxicities that significantly degrade patients’quality of ... Cancer continues to pose a formidable challenge in global health,with conventional treatments such as chemotherapy and radiotherapy often resulting in severe toxicities that significantly degrade patients’quality of life and restrict therapeutic outcomes.Addressing this pressing issue,this review presents a thorough and systematic analysis of innovative and emerging strategies designed to minimize the toxicity induced by treatment,while maintaining or even enhancing antitumor efficacy.The focus is on six promising therapeutic approaches:combination therapies utilizing natural bioactive products,molecularly targeted therapies,immunotherapies,nanotechnology-mediated drug delivery systems,adjunct traditional Chinese medicine interventions,and low-dose spatiotemporally concerted regimens.Each approach employs unique mechanisms—such as enhanced targeting precision,immune system activation,tumor microenvironment reprogramming,and multi-component synergistic effects—to mitigate damage to normal tissues and reduce systemic adverse reactions.Despite promising preclinical and clinical advancements,several challenges persist,including drug resistance,high economic costs,a lack of reliable predictive biomarkers,and complexities in clinical translation and regulatory approval.Looking ahead,the incorporation of artificial intelligence,multi-omics profiling,and novel biomimetic nanotechnologies offers unprecedented opportunities for developing highly personalized,low-toxicity treatment frameworks.This review highlights a fundamental shift in oncology towards precision medicine that balances efficacy with safety,demonstrating the transformative potential of these strategies in shaping the future of cancer therapy and enhancing patient care globally. 展开更多
关键词 CANCER low toxicity combined therapies targeted therapies IMMUNOTHERAPIES nanotherapies traditional Chinese medicine spatiotemporally concerted therapies
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《声学学报》《Chinese Journal of Acoustics》简介
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《声学学报》 北大核心 2026年第1期F0002-F0002,共1页
一、声学学报(中、英文版)两刊,是中国科学院声学研究所主办,中国声学学会、声学学报编辑委员会编辑出版的学术性刊物,刊载具有创造性的声学研究论文、实验性论文和重要应用性论文(包括实验工作、理论和应用研究、仪器研制),评述性论文... 一、声学学报(中、英文版)两刊,是中国科学院声学研究所主办,中国声学学会、声学学报编辑委员会编辑出版的学术性刊物,刊载具有创造性的声学研究论文、实验性论文和重要应用性论文(包括实验工作、理论和应用研究、仪器研制),评述性论文以编委会约定者为限。二、来稿须知(1)交稿时做到清稿、定稿;(2)要求内容正确,层次分明,文字简练,并正确使用标点符号;(3)名词、术语、符号、单位等一律使用国家标准;(4)论文和快报都应以描述自己的创造性工作成果为主,一般的或在文献中已有的数学推导过程一律不可重复;(5)论文题名应简练准确地反映论文研究内容,并避免使用缩略词、特殊符号、非常用专业术语等;(6)附中英文摘要、关键词和PACS数,摘要应为报道性摘要,包括研究目的、方法、结果、结论四要素;关键词应能准确反映论文研究主题,且为规范术语;(7)图和表均应具有自明性,图表中的文字均使用中文,图题和表题务必简明扼要;(8)顺序标引文献,著录信息应完整,未公开发表的资料不宜引用。 展开更多
关键词 Chinese Journal of Acoustics 声学学报
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《声学学报》《Chinese Journal of Acoustics》简介
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《声学学报》 北大核心 2026年第2期F0002-F0002,共1页
一、声学学报(中、英文版)两刊,是中国科学院声学研究所主办,中国声学学会、声学学报编辑委员会编辑出版的学术性刊物,刊载具有创造性的声学研究论文、实验性论文和重要应用性论文(包括实验工作、理论和应用研究、仪器研制),评述性论文... 一、声学学报(中、英文版)两刊,是中国科学院声学研究所主办,中国声学学会、声学学报编辑委员会编辑出版的学术性刊物,刊载具有创造性的声学研究论文、实验性论文和重要应用性论文(包括实验工作、理论和应用研究、仪器研制),评述性论文以编委会约定者为限。二、来稿须知(1)交稿时做到清稿、定稿;(2)要求内容正确,层次分明,文字简练,并正确使用标点符号;(3)名词、术语、符号、单位等一律使用国家标准;(4)论文和快报都应以描述自己的创造性工作成果为主,一般的或在文献中已有的数学推导过程一律不可重复;(5)论文题名应简练准确地反映论文研究内容,并避免使用缩略词、特殊符号、非常用专业术语等. 展开更多
关键词 Chinese Journal of Acoustics 声学学报
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天津中草药杂志社简介
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《药物评价研究》 北大核心 2026年第1期F0004-F0004,共1页
天津中草药杂志社为天津药物研究院全资子公司,成立于2009年,致力于整个药学研究领域以推动我国药学事业的发展为己任,编辑出版4本期刊:《中草药》《Chinese Herbal Medicines》《现代药物与临床》《药物评价研究》。
关键词 现代药物与临床 Chinese Herbal Medicines
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《中医杂志(英文版)》欢迎投稿
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《中医杂志》 北大核心 2026年第3期322-322,共1页
Journal of Traditional Chinese Medicine[《中医杂志(英文版)》](ISSN0255-2922,CN11-2167/R,双月刊)由中华中医药学会与中国中医科学院联合主办,是我国中医药界具有权威的中医药英文科技期刊,现发行和交换90多个国家和地区。《中医杂... Journal of Traditional Chinese Medicine[《中医杂志(英文版)》](ISSN0255-2922,CN11-2167/R,双月刊)由中华中医药学会与中国中医科学院联合主办,是我国中医药界具有权威的中医药英文科技期刊,现发行和交换90多个国家和地区。《中医杂志(英文版)》自1981年创刊以来一直坚持正确的办刊宗旨,国际影响力不断提升。2010年入选SCI-E(《科学引文索引》扩刊版),2011年获得中国中医科学院自主选题项目资助,2013年获得“中国科技期刊国际影响力提升计划”资助,自2012年起连续被评为“中国最具国际影响力学术期刊”,2023年再次入选“T1级中医药英文科技期刊目录”。 展开更多
关键词 中医杂志 Journal of Traditional Chinese Medicine
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Intervention effect and mechanism of Compound Herba Gueldenstaedtiae in a mouse model of breast hyperplasia
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作者 Wu Yilin Tian Hongying +8 位作者 Sun Jiale Jiao Jiajia Zhao Zihan Shao Jinhuan Zhao Kaiyue Zhou Min Li Qian Li Zexin Yue Changwu 《中国组织工程研究》 北大核心 2026年第17期4377-4389,共13页
BACKGROUND:Breast hyperplasia is a common benign breast disease mainly caused by endocrine disorders,manifested as abnormal hyperplasia of breast tissue.In recent years,traditional Chinese medicine compounds and probi... BACKGROUND:Breast hyperplasia is a common benign breast disease mainly caused by endocrine disorders,manifested as abnormal hyperplasia of breast tissue.In recent years,traditional Chinese medicine compounds and probiotics have shown good potential in regulating the endocrine system and improving the intestinal microecology,providing new ideas for the treatment of breast hyperplasia.OBJECTIVE:To explore the effects and mechanisms of traditional Chinese medicine compounds and fermented probiotic compounds on breast hyperplasia in mice,providing new theoretical and experimental bases for the clinical treatment and prevention of breast hyperplasia.METHODS:(1)Network pharmacology tools were used to predict the anti-breast-hyperplasia activity of Herba Gueldenstaedtiae(Euphorbia humifusa),as well as its potential targets and signaling pathways.The databases included:TCMSP,OMIM,GeneCards database,UniProt website,Venny2.1.0 website,Metascape,HERB website,and STRING database,all of which are open-access databases.Network pharmacology can predict and screen key information such as the targets corresponding to the active ingredients of traditional Chinese medicine,disease targets,and action pathways through network analysis and computer-system analysis.Therefore,it has been increasingly widely used in the research of traditional Chinese medicine.(2)A breast hyperplasia model was induced in mice by injecting estrogen and progesterone.Mice in the normal blank group were injected intraperitoneally with normal saline every day.Mice in the model group and drugadministration groups were injected intraperitoneally with estradiol benzoate injection at a concentration of 0.5 mg/kg every day for 25 days.From the 26th day,the injection of estradiol benzoate injection was stopped.Mice in the normal blank group were injected intramuscularly with normal saline every day,and mice in the model group and drug-administration groups were injected intramuscularly with progesterone injection at a concentration of 5 mg/kg for 5 days.After the model was established,each group was given drugs respectively.The normal blank group and the model group were gavaged with 0.2 mL/d of normal saline;the positive blank group(Xiaozheng Pill group)was gavaged with an aqueous solution of Xiaozheng Pill at 0.9 mg/g;the low-,medium-and high-dose groups of Compound Herba Gueldenstaedtiae were gavaged with an aqueous solution of the compound medicine at 0.75,1.5,and 3.0 mg/(g·d)respectively;the low-,medium-and high-dose groups of traditional Chinese medicine-bacteria fermentation were gavaged with an aqueous solution of the compound medicine at 0.75,1.5,and 3.0 mg/(g·d)respectively.The administration was continuous for 30 days.RESULTS AND CONCLUSION:(1)The results of network pharmacology research showed that the Compound Herba Gueldenstaedtiae(Euphorbia humifusa)contained 46 active ingredients,which were related to 1213 potential targets.After comparison with 588 known breast-hyperplasia targets,it was speculated that 50 of these targets might be related to the direct effect of the compound on breast hyperplasia.(2)After drug intervention,there was no significant change in the high-dose group of Compound Herba Gueldenstaedtiae compared with the normal blank group.The liver indicators of the other intervention groups all significantly decreased(P<0.05).(3)In terms of kidney and uterine indicators,the medium-dose group of Compound Herba Gueldenstaedtiae decreased significantly compared with the normal blank group(P<0.05).In terms of the uterine index,the model group increased significantly compared with the normal blank group(P<0.01).(4)After 1-month drug treatment,the number of lobules and acini in the breast tissue of the Xiaozheng Pill group,the low,medium,and high-dose group of Compound Herba Gueldenstaedtiae,the low,medium,and highdose groups of traditional Chinese medicine-bacteria fermentation decreased,and the duct openings narrowed.With the increase of drug dose,diffuse hyperplasia of breast tissue was significantly improved.(5)The ELISA results showed that compared with the model group,the estrogen level was lower in the medium-dose group of traditional Chinese medicine-bacteria fermentation after the intervention(P<0.05).In addition,the follicle-stimulating hormone level in the low-dose group of Compound Herba Gueldenstaedtiae was lower than that of the model group(P<0.05).(6)The intervention in the mouse model led to changes in the abundance of short chain fatty acids and intestinal flora in all groups.To conclude,the Compound Herba Gueldenstaedtiae and its probiotic fermentation products significantly improved mammary gland hyperplasia in mice by regulating hormone levels,improving the structure of the gut microbiota,and increasing the content of shortchain fatty acids,providing new ideas and potential sources of drugs for the treatment of breast hyperplasia. 展开更多
关键词 Herba Gueldenstaedtiae traditional Chinese medicine compound mice with breast hyperplasia microbial fermentation gut microbiota network pharmacology short-chain fatty acids hormone levels inflammatory response endocrine disorders
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《中医杂志(英文版)》欢迎投稿
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《中医杂志》 北大核心 2026年第4期374-374,共1页
Journal of Traditional Chinese Medicine[《中医杂志(英文版)》](ISSN0255-2922,CN11-2167/R,双月刊)由中华中医药学会与中国中医科学院联合主办,是我国中医药界具有权威的中医药英文科技期刊,现发行和交换90多个国家和地区。
关键词 Journal of Traditional Chinese Medicine
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《中医杂志(英文版)》欢迎投稿
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《中医杂志》 北大核心 2026年第1期78-78,共1页
Journal of Traditional Chinese Medicine[《中医杂志(英文版)》](ISSN0255-2922,CN11-2167/R,双月刊)由中华中医药学会与中国中医科学院联合主办,是我国中医药界具有权威的中医药英文科技期刊,现发行和交换90多个国家和地区。《中医杂... Journal of Traditional Chinese Medicine[《中医杂志(英文版)》](ISSN0255-2922,CN11-2167/R,双月刊)由中华中医药学会与中国中医科学院联合主办,是我国中医药界具有权威的中医药英文科技期刊,现发行和交换90多个国家和地区。《中医杂志(英文版)》自1981年创刊以来一直坚持正确的办刊宗旨,国际影响力不断提升。 展开更多
关键词 Journal of Traditional Chinese Medicine
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《中医杂志(英文版)》欢迎投稿
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《中医杂志》 北大核心 2026年第2期148-148,共1页
Journal of Traditional Chinese Medicine[《中医杂志(英文版)》](ISSN0255-2922,CN11-2167/R,双月刊)由中华中医药学会与中国中医科学院联合主办,是我国中医药界具有权威的中医药英文科技期刊,现发行和交换90多个国家和地区。
关键词 Journal of Traditional Chinese Medicine
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《中国组织工程研究》杂志年度稿约
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作者 张楠 赵萌 王莉莎 《中国组织工程研究》 北大核心 2026年第1期260-268,共9页
1关于杂志《中国组织工程研究》(Chinese Journal of Tissue Engineering Research,CJTER)杂志是国家卫健委主管、中国康复医学会主办的国家级双核心期刊,是目前国内专注组织工程研究的经同行评议的开放获取期刊,期刊官方网站为www.cjte... 1关于杂志《中国组织工程研究》(Chinese Journal of Tissue Engineering Research,CJTER)杂志是国家卫健委主管、中国康复医学会主办的国家级双核心期刊,是目前国内专注组织工程研究的经同行评议的开放获取期刊,期刊官方网站为www.cjter.com。以面向国际立足本土为出版宗旨,以严谨的审稿流程,优质的期刊编辑服务,快速的出版周期,办中国组织工程领域最优秀的学术期刊为工作目标。 展开更多
关键词 Chinese Journal of Tissue Engineering Research
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Needles of Love without Borders
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作者 XIA YUANYUAN 《China Today》 2026年第3期68-69,共2页
International patients are flocking to Hainan for healing through the ancient technique of traditional Chinese medicine.SAREN,a traditional Chinese medicine(TCM)doctor,keeps vipbooks filled with warm messages in var... International patients are flocking to Hainan for healing through the ancient technique of traditional Chinese medicine.SAREN,a traditional Chinese medicine(TCM)doctor,keeps vipbooks filled with warm messages in various languages in her consulting room at Sanya International Friendship Sanatorium of TCM.These expressions of gratitude not only document a long medical career,but also vividly testify to how a Chinese doctor has used acupuncture to cure patients from around the world. 展开更多
关键词 LOVE NEEDLES acupuncture healing expressions gratitude traditional chinese medicine tcm doctorkeeps traditional chinese medicinesarena traditional chinese medicine
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Young Musicians Bring Ancient Instruments into the Modern Era
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作者 Li Xiaoyang 《China Report ASEAN》 2026年第3期56-57,共2页
Chinese video game Black Myth:Wukong has been a h it among gaming enthusiasts worldwide since its release in 2024, its breakout success demonstrating the potential global appeal of traditional Chinese culture. Based o... Chinese video game Black Myth:Wukong has been a h it among gaming enthusiasts worldwide since its release in 2024, its breakout success demonstrating the potential global appeal of traditional Chinese culture. Based on the 16th-century classic novel Journey to the West, the game not only introduces international audiences to Chinese literature but has also become a far-reaching platform for traditional Chinese music. 展开更多
关键词 traditional chinese culture Black Myth Wukong traditional chinese music young musicians ancient instruments modern era global appeal Chinese video game
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Spirit Over the Saddle:One of the twelve animals of the Chinese zodiac, the Horse embodies vitality, freedom and the spirit of ambition
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作者 LI YIN 《ChinAfrica》 2026年第2期56-57,共2页
In the Chinese lunar calendar,2026 ushers in the Year of the Horse,a creature that has carried humanity across continents and through centuries.More than a marker of time,the horse embodies vitality,courage,and the re... In the Chinese lunar calendar,2026 ushers in the Year of the Horse,a creature that has carried humanity across continents and through centuries.More than a marker of time,the horse embodies vitality,courage,and the relentless spirit to move forward,qualities that resonate not only in China but across the landscapes of many African societies. 展开更多
关键词 HORSE VITALITY chinese zodiac year horse chinese lunar calendar AMBITION COURAGE forward movement
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Aims and Scope
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《Chinese Journal of Polymer Science》 2026年第1期I0001-I0001,共1页
Chinese Journal of Polymer Science(CJPS)is a monthly journal published in English and sponsored by the Chinese Chemical Society and the Institute of Chemistry,Chinese Academy of Sciences.CJPS is edited by a distinguis... Chinese Journal of Polymer Science(CJPS)is a monthly journal published in English and sponsored by the Chinese Chemical Society and the Institute of Chemistry,Chinese Academy of Sciences.CJPS is edited by a distinguished Editorial Board headed by Professor Qi-Feng Zhou and supported by an International Advisory Board in which many famous active polymer scientists all over the world are included. 展开更多
关键词 English Publication Chinese Chemical Society Monthly Journal Institute Chemistry Chinese Academy Sciences International Advisory Board Polymer Science editorial board Chinese Journal Polymer Science
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CHINA'S ECONOMIC RESILIENCE:AN OVERVIEW IN 2025
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作者 Zhang Junmian 《China Report ASEAN》 2026年第2期60-61,共2页
The Chinese word韧性(rènxìng,resilience),which resonated deeply with the public in2025,ranked No.1 on the annual list of top10 Chinese buzzwords recently unveiled by Shanghai-based language and literature ma... The Chinese word韧性(rènxìng,resilience),which resonated deeply with the public in2025,ranked No.1 on the annual list of top10 Chinese buzzwords recently unveiled by Shanghai-based language and literature magazine Yaowen Jiaozi.Originating from the concept of being“pliant yet solid”,it embodies an unyielding spirit.In economics,resilience denotes the capacity to withstand,absorb,and recover from external shocks. 展开更多
关键词 yaowen jiaozi BUZZWORDS Chinese economic resilience chinese buzzwords economic resilience RESILIENCE
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The“Horse Power”of China
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作者 Zhang Hui 《China Today》 2026年第3期2-2,共1页
In Chinese culture,the horse is a symbol of vigor,strength,and resilience,heralding a future of steady progress and prosperous development,President Xi Jinping said when extending Spring Festival greetings at a recept... In Chinese culture,the horse is a symbol of vigor,strength,and resilience,heralding a future of steady progress and prosperous development,President Xi Jinping said when extending Spring Festival greetings at a reception on February 14 in Beijing to ring in the Chinese New Year-the Year of the Horse.This statement,resonating with the heart of the world’s most populous national celebration,offers a profound lens through which to understand not just a festival,but the pulsating energy of contemporary China. 展开更多
关键词 Chinese culture horse power STRENGTH Year Horse RESILIENCE Chinese New Year VIGOR Spring Festival
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Safeguarding global safety with Chinese wisdom Interview with Ma Dejun, first Chinese winner of the IEC Lord Kelvin Award
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作者 Jin Jili(Translated) 《China Standardization》 2026年第2期16-23,共8页
At the IEC,Chinese experts have been contributing their expertise to international standardization.As one of them,Ma Dejun has grown from an inexperienced explorer in the field of standardization into a distinguished ... At the IEC,Chinese experts have been contributing their expertise to international standardization.As one of them,Ma Dejun has grown from an inexperienced explorer in the field of standardization into a distinguished expert driving the development of international standards in key sectors over the past 35 years.He was presented with the 2025 Lord Kelvin Award at the 89th IEC General Meeting held in New Delhi,India,in September 2025.Thus,he became the first Chinese expert to receive the highest honor bestowed by the IEC.In an exclusive interview with Ma Dejun,he reviewed his original aspiration behind his decades-long journey in international standardization,shared his experience and insights on promoting international standards,and looked forward to China's future role on the international standardiz ation stage. 展开更多
关键词 Chinese experts lord kelvin award development international standards IEC international standardization Chinese wisdom global safety standardization expertise
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Chinese Journal of Polymer Science
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《Chinese Journal of Polymer Science》 2026年第2期I0001-I0003,共3页
Aims and Scope Chinese Journal of Polymer Science(CJPS)is a monthly journal published in English and sponsored by the Chinese Chemical Society and the Institute of Chemistry,Chinese Academy of Sciences.CJPS is edited ... Aims and Scope Chinese Journal of Polymer Science(CJPS)is a monthly journal published in English and sponsored by the Chinese Chemical Society and the Institute of Chemistry,Chinese Academy of Sciences.CJPS is edited by a distinguished Editorial Board headed by Professor Qi-Feng Zhou and supported by an International Advisory Board in which many famous active polymer scientists all over the world are included. 展开更多
关键词 Monthly Journal Chinese Academy Sciences Polymer Science advisory board Institute Chemistry editorial board International Advisory Board Chinese Chemical Society
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Inheritance,Innovation and Development,Intellectual Property Protection of Traditional Chinese Medicine in Hubei Province
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作者 Yuanpeng SUN Fei QU +4 位作者 Jianda SUN Yanping ZHANG Pei SUN Zhiyang YUAN Zhiguo SUN 《Asian Agricultural Research》 2026年第1期1-13,共13页
Chinese medicinal materials are the material basis for the inheritance and development of traditional Chinese medicine.Intellectual property protection for the entire industrial chain of traditional Chinese medicinal ... Chinese medicinal materials are the material basis for the inheritance and development of traditional Chinese medicine.Intellectual property protection for the entire industrial chain of traditional Chinese medicinal materials promotes the inheritance and innovation of traditional Chinese medicine,and contributes to rural revitalization and the building of an agricultural power.This article provides an overview of the traditional Chinese medicinal materials in Hubei Province.It conducts a detailed investigation into the intellectual property resources of the province s traditional Chinese medicinal materials from aspects such as traditional knowledge,genetic resources,new plant varieties,patents,geographical indications,and trademarks.It analyzes the eight main problems in the protection,inheritance,and innovative development of intellectual property rights,and puts forward corresponding suggestions,such as establishing an intellectual property rights rule system for specific fields of traditional Chinese medicinal materials,promoting the"Famous Brand Action in Rural Areas",and building a"Hubei s Sixteen Superior Herbs"cluster of traditional Chinese medicinal materials. 展开更多
关键词 Chinese medicinal materials Intellectual property Inheritance and innovation Traditional Chinese medicine Agricultural power Hubei Province
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