Fixture is an important manufacturing activity. A fixture design system based on case-based reasoning (CBR) is proposed in this paper. A new method of case representation on the basis of fixture function is presented,...Fixture is an important manufacturing activity. A fixture design system based on case-based reasoning (CBR) is proposed in this paper. A new method of case representation on the basis of fixture function is presented, where the case representation is constituted of workpiece knowledge, processing feature knowledge, and fixture feature knowledge. Running the prototype system shows that the knowledge representation method, using cases, s a better way to transform and explain the design knowledge.展开更多
As the most critical part of post-graduate education,the Chinese government launched Standard Resident Training in 2013 to solve the regional inequality of medical quality and meet the increasing social requirement fo...As the most critical part of post-graduate education,the Chinese government launched Standard Resident Training in 2013 to solve the regional inequality of medical quality and meet the increasing social requirement for better medical service.We integrated problem-based learning(PBL)and case-based learning(CBL)in the Endodontics Standard Resident Training.By evaluating with objective parameters including theoretical knowledge and clinical practice skill,and subjective parameters including questionnaire,it was found that PBL+CBL played a positive role in endodontic resident training with a significant difference(P<0.05).This combined training model is instructive for China’s resident training,and this result can provide a rudimentary reference to current postgraduate teaching reform.展开更多
Objective:To explore the effect of implementing the case-based three-dimensional teaching method guided by evidence-based thinking in the teaching of trainee nurses in the rehabilitation department.Method:Eighty nursi...Objective:To explore the effect of implementing the case-based three-dimensional teaching method guided by evidence-based thinking in the teaching of trainee nurses in the rehabilitation department.Method:Eighty nursing practice nurses who were conducting clinical practice learning in the Rehabilitation Department of Deyang People’s Hospital from June 2024 to May 2025 were selected as the research subjects.By using the controlled grouping method,the practice nurses from June 2024 to November 2024 were taken as the control group(n=40).The period from December 2024 to May 2025 was taken as the experimental group(n=40 students),the control group was taught by traditional teaching methods,and the experimental group was taught by evidence-based nursing combined with case teaching method.The clinical thinking ability,autonomous learning ability,exit assessment scores and teaching satisfaction of the two groups of intern nurses at the time of leaving the department were compared.Results:At the time of leaving the department,the scores of each dimension and the total score of clinical thinking ability of the intern nurses in the experimental group were higher than those in the control group(t=9.268,6.354,6.199)9.694,all p<0.05).At the time of leaving the department the scores of each dimension and the total score of the autonomous learning ability of the intern nurses in the experimental group were higher than those in the control group(t=6.998,7.333,5.503,5.977,22.244)all p<0.05).At the time of leaving the department the theoretical assessment scores and operational assessment scores of the experimental group were both higher than those of the control group(t=14.546,11.676,all p<0.05).At the time of graduation,the teaching satisfaction of the experimental group was higher than that of the control group(χ^(2)=7.314,p<0.05.Conclusion:The adoption of the case-based three-dimensional teaching.Rehabilitation method guided by the evidence-based ideology during the teaching process can effectively improve the clinical thinking ability,autonomous learning ability,departmental assessment results and teaching satisfaction of the intern nurses in the rehabilitation department,which is worthy of reference.展开更多
Objective Observational studies have found associations between inflammatory bowel disease(IBD)and the risk of dementia,including Alzheimer’s dementia(AD)and vascular dementia(VD);however,these findings are inconsist...Objective Observational studies have found associations between inflammatory bowel disease(IBD)and the risk of dementia,including Alzheimer’s dementia(AD)and vascular dementia(VD);however,these findings are inconsistent.It remains unclear whether these associations are causal.Methods We conducted a meta-analysis by systematically searching for observational studies on the association between IBD and dementia.Mendelian randomization(MR)analysis based on summary genome-wide association studies(GWASs)was performed.Genetic correlation and Bayesian colocalization analyses were used to provide robust genetic evidence.Results Ten observational studies involving 80,565,688 participants were included in this metaanalysis.IBD was significantly associated with dementia(risk ratio[RR]=1.36,95%CI=1.04-1.78;I2=84.8%)and VD(RR=2.60,95%CI=1.18-5.70;only one study),but not with AD(RR=2.00,95%CI=0.96-4.13;I^(2)=99.8%).MR analyses did not supported significant causal associations of IBD with dementia(dementia:odds ratio[OR]=1.01,95%CI=0.98-1.03;AD:OR=0.98,95%CI=0.95-1.01;VD:OR=1.02,95%CI=0.97-1.07).In addition,genetic correlation and co-localization analyses did not reveal any genetic associations between IBD and dementia.Conclusion Our study did not provide genetic evidence for a causal association between IBD and dementia risk.The increased risk of dementia observed in observational studies may be attributed to unobserved confounding factors or detection bias.展开更多
Reference values of erythrocyte sedimentation rate(ESR)are the key to interpret ESR blood test in clinic.The common local reference ESR values are more accuracy in blood test that are established with natural geograph...Reference values of erythrocyte sedimentation rate(ESR)are the key to interpret ESR blood test in clinic.The common local reference ESR values are more accuracy in blood test that are established with natural geographical factors by using the multiple linear regression(MLR)model and the artificial neural network(ANN).These knowledge-based methods have limitations since the knowledge domains of ESR and natural geographical factors are limited.This paper presents a new cases-depended model to establish reference ESR values with natural geographical factors and location using case-based reasoning(CBR)since knowledge domain of ESR and geographical factors is weak.Overall 224 local normal ESR values of China that calculated from 13623 samples were obtained,and the corresponding natural geographical factors and location that include altitude,sunshine hours,relative humidity,temperature,precipitation,annual temperature range and annual average wind speed were obtained from the National Geomatics Center of China.CBR was used to predict the unseen local reference ESR values with cases.The average absolute deviation(AAD),mean square error(MSE),prediction accuracy(PA),and Pearson correlation coefficient(r)between the observed and estimated data of proposed model is 33.07%,9.02,66.93% and 0.78,which are better than those of ANN and MLR model.The results show that the proposed model provides higher prediction accuracy than those of the artificial neural network and multiple linear regression models.The predicted values are very close to the observed values.Model results show significant agreement of cases data.Consequently,the model is used to predict the unseen local reference ESR with natural geographical factors and location.In spatial,the highest ESR reference areas are distributed in the southern-western district of China that includes Sichuan,Chongqing,Guangxi and Guizhou provinces,and the reference ESR values are greater than 23 mm/60 min.The higher ESR reference values are distributed in the middle part and northern-eastern of China which include Hubei,Henan,Shaanxi,Shanxi,Jilin and Heilongjiang provinces,and the reference ESR values are greater than 18 mm/60min.The lowest ESR reference values are distributed in the northern-western of China that includes Tibet and Xinjiang,and the reference ESR values are lower than 5 mm/60min.展开更多
This paper proposes an interdisciplinary talent training model that combines foreign language education with area studies.The model aims to cultivate international ocean affairs professionals with cross-cultural commu...This paper proposes an interdisciplinary talent training model that combines foreign language education with area studies.The model aims to cultivate international ocean affairs professionals with cross-cultural communication skills,in-depth regional and country knowledge,and practical expertise in ocean affairs.Additionally,the paper presents specific training pathways and policy recommendations for implementing this model.展开更多
In modern society,the globalization of literary works is evident,with exceptional literary pieces from various countries spreading worldwide.Among these,children’s literature,due to the specificity of its target audi...In modern society,the globalization of literary works is evident,with exceptional literary pieces from various countries spreading worldwide.Among these,children’s literature,due to the specificity of its target audience,imposes distinct requirements on children’s books,compelling translators to approach the text from a child’s perspective.“The Little Prince”has renowned both within and outside of China,and a careful reading of this work can provide us with much inspiration.To this end,the present study adopts the perspective of Gideon Toury’s Descriptive Translation Studies to conduct an in-depth analysis of the different English and Chinese translations in conjunction with the original French novel.This approach aims to better guide literary research and explores translation methods for children’s literature through the analysis of translation norms and rules.展开更多
BACKGROUND Gastrointestinal endoscopy technology has significantly improved the diagnostic accuracy and the successful treatment of gastrointestinal diseases.However,a series of ethical issues have emerged,such as exp...BACKGROUND Gastrointestinal endoscopy technology has significantly improved the diagnostic accuracy and the successful treatment of gastrointestinal diseases.However,a series of ethical issues have emerged,such as expanding treatment indications,which affect the fair distribution of medical resources.There is limited research on ethical issues in the field of digestive endoscopy.AIM To investigate the level of ethical awareness among gastrointestinal endoscopy practitioners and analyze the ethical issues involved in gastrointestinal endoscopy technology.METHODS A questionnaire survey was performed to collect relevant data(gender,age,degree of education,professional title,personnel category,the level of understanding medical ethical principles,ethics training and its learning pathways)from gastrointestinal endoscopy practitioners at the Second Hospital of Dalian Medical University and Dalian Friendship Hospital,including licensed physicians and nurses(including trainees and graduate students).RESULTS The majority of gastrointestinal endoscopy practitioners have received training on ethics,but there is still considerable room for improvement in their ethical awareness.Different learning pathways may affect the mastery of ethical principles, and understanding of ethical principles is more easily achieved through hospital ethics institutions.CONCLUSIONTo address the ethical issues in gastrointestinal endoscopy technology, it is necessary to enhance the humanisticeducation of gastrointestinal endoscopy practitioners, incorporate ethical standards into the technology assessmentprocess, and establish a patient-centered diagnostic and treatment model to improve the ethical awareness of practitionersand achieve a balance between technology and ethics.展开更多
To increase the efficiency of the multidisciplinary optimization of aircraft, an aerodynamic approximation model is improved. Based on the study of aerodynamic approximation model constructed by the scaling correction...To increase the efficiency of the multidisciplinary optimization of aircraft, an aerodynamic approximation model is improved. Based on the study of aerodynamic approximation model constructed by the scaling correction model, case-based reasoning technique is introduced to improve the approximation model for optimization. The aircraft case model is constructed by utilizing the plane parameters related to aerodynamic characteristics as attributes of cases, and the formula of case retrieving is improved. Finally, the aerodynamic approximation model for optimization is improved by reusing the correction factors of the most similar aircraft to the current one. The multidisciplinary optimization of a civil aircraft concept is carried out with the improved aerodynamic approximation model. The results demonstrate that the precision and the efficiency of the optimization can be improved by utilizing the improved aerodynamic approximation model with ease-based reasoning technique.展开更多
Through the questionnaire survey and comparative studies on tourist satisfaction of tourism services among three world heritage sites,i.e.Huangshan Mountain,Lushan Mountain and Wuyi Mountain,this study pointed out the...Through the questionnaire survey and comparative studies on tourist satisfaction of tourism services among three world heritage sites,i.e.Huangshan Mountain,Lushan Mountain and Wuyi Mountain,this study pointed out the problems in tourism services of three scenic areas and then put forward relevant countermeasures for the management of scenic areas.展开更多
The increasing complexity and size of configuration knowledge bases requres the provisionof advanced methods supporting the development of the actual configuration process and design reuse.A new framework to find a fe...The increasing complexity and size of configuration knowledge bases requres the provisionof advanced methods supporting the development of the actual configuration process and design reuse.A new framework to find a feasible and practical product configuration method is presented in masscustomization. The basic idea of the appoach is to integrate case-based reasoning (CBR) with a con-straint satisfaction problem(CSP). The similarity measure between a crisp and range is also given,which is common in case retrieves. Based on the configuration model, a product platform and customerneeds, case adaptation is carried out with the repair-based algorithm. Lastly, the methodology in theelevator configuration design domain is tested.展开更多
An improved case-based reasoning （CBR） method was proposed to predict the endpoint temperature of molten steel in Ruhrstahl Heraeus （RH） process. Firstly, production data were analyzed by multiple linear regressio...An improved case-based reasoning （CBR） method was proposed to predict the endpoint temperature of molten steel in Ruhrstahl Heraeus （RH） process. Firstly, production data were analyzed by multiple linear regressions and a pairwise comparison matrix in analytic hierarchy process （AHP） was determined by this linear regression＇s coefficient. The weights of various influencing factors were obtained by AHP. Secondly, the dividable principles of case base including ＂0-1＂ and ＂breakpoint＂ were proposed, and the case base was divided into several homogeneous parts. Finally, the improved CBR was compared with ordinary CBR, which is based on the even weight and the single base. The results show that the improved CBR has a higher hit rate for predicting the endpoint temperature of molten steel in RH.展开更多
The design of the two-step gear reducer is a tedious and time-consuming process. For the purpose of improving the efficiency and intelligence of design process, case-based reasoning（CBR） technology was applied to th...The design of the two-step gear reducer is a tedious and time-consuming process. For the purpose of improving the efficiency and intelligence of design process, case-based reasoning（CBR） technology was applied to the design of the two-step gear reducer. Firstly, the current design method for the two-step gear reducer was analyzed and the principle of CBR was described. Secondly, according to the characteristics of the reducer, three key technologies of CBR were studied and the corresponding methods were provided, which are as follows： （a） an object-oriented knowledge representation method, （b） a retrieval method combining the nearest neighbor with the induction indexing, and （c） a case adaptation algorithm combining the revision based on rule with artificial revision. Also, for the purpose of improving the credibility of case retrieval, a new method for determining the weights of characteristics and a similarity formula were presented, which is a combinatorial weighting method with the analytic hierarchy process（AHP） and roughness set theory. Lastly, according to the above analytic results, a design system of the two-step gear reducer on CBR was developed by VC＋＋, UG and Access 2003. A new method for the design of the two-step gear reducer is provided in this study. If the foregoing developed system is applied to design the two-step gear reducer, design efficiency is improved, which enables the designer to release from the tedious design process of the gear reducer so as to put more efforts on innovative design. The study result fully reflects the feasibility and validity of CBR technology in the process of the design of the mechanical parts.展开更多
The current method of case-based design (CBD) can be well practiced forconfiguration design in which design experience knowledge is involved. However, since the designcase is confined to a certain application domain, ...The current method of case-based design (CBD) can be well practiced forconfiguration design in which design experience knowledge is involved. However, since the designcase is confined to a certain application domain, it is difficult for CBD to be applied toconceptual design process that develops concepts to meet design specifications. Firstly, a functionfactor description space is erected to provide an exhibition room for all functions of design cases.Next, the approach for identifying the space state of function factor in description space isproposed, including the determination of the similarities between function factors of design case.And then a general object-oriented representation for design case is presented by bringing the classof function and in-out flow into the current case representation. Finally, a living example forelectro-pet design that illustrates the implementation of the method for case-based conceptualdesign based on distributed design case repositories is described.展开更多
Selecting a proper set of covariates is one of the most important factors that influence the accuracy of digital soil mapping(DSM).The statistical or machine learning methods for selecting DSM covariates are not avail...Selecting a proper set of covariates is one of the most important factors that influence the accuracy of digital soil mapping(DSM).The statistical or machine learning methods for selecting DSM covariates are not available for those situations with limited samples.To solve the problem,this paper proposed a case-based method which could formalize the covariate selection knowledge contained in practical DSM applications.The proposed method trained Random Forest(RF)classifiers with DSM cases extracted from the practical DSM applications and then used the trained classifiers to determine whether each one potential covariate should be used in a new DSM application.In this study,we took topographic covariates as examples of covariates and extracted 191 DSM cases from 56 peer-reviewed journal articles to evaluate the performance of the proposed case-based method by Leave-One-Out cross validation.Compared with a novices’commonly-used way of selecting DSM covariates,the proposed case-based method improved more than 30%accuracy according to three quantitative evaluation indices(i.e.,recall,precision,and F1-score).The proposed method could be also applied to selecting the proper set of covariates for other similar geographical modeling domains,such as landslide susceptibility mapping,and species distribution modeling.展开更多
Temperature control is the key of Ruhrstahl-Heraeus (RH) process in steelmaking plant. The accuracy of RH control model greatly affects the molten steel temperature fluctuation. To obtain RH control model with higher ...Temperature control is the key of Ruhrstahl-Heraeus (RH) process in steelmaking plant. The accuracy of RH control model greatly affects the molten steel temperature fluctuation. To obtain RH control model with higher accuracy, an improved case-based reasoning (CBR) model based on attribute weights optimized by genetic algorithm (GA) was proposed. The fitness function in GA was determined according to the prediction accuracy of end temperature of molten steel in RH;then, GA is used to optimize all the attribute weights based on known case base. An improved CBR model that contains the optimized attribute weights was applied to predict end temperature of molten steel in RH, and the prediction accuracy wascalculated. Four methods, CBR based on attribute weights optimized by GA (CBR-GA), ordinary CBR, back propagation neural network (BPNN) and multiple linear regression (MLR) method were employed for comparison. The results show that in the error range of [- 3 ℃, 3 ℃],[- 5 ℃, 5 ℃],[- 7 ℃, 7 ℃] and [- 10 ℃, 10 ℃], the prediction accuracy of CBR-GA was improved by 19.99%, 28.19%, 27.11% and 16.3%, respectively, than that of MLR. Compared with BPNN, the prediction accuracy increased by 3.22%, 7.44%, 5.29% and 2.40%, respectively. Compared with ordinary CBR, the accuracy increased by 5.43%, 5.80%, 4.66% and 2.27%, respectively.展开更多
OBJECTIVE:To assess the effect of case-based learning(CBL)in the education of Traditional Chinese Medicine(TCM).METHODS:The studies concerning TCM courses designed with CBL were included by searching the databases of ...OBJECTIVE:To assess the effect of case-based learning(CBL)in the education of Traditional Chinese Medicine(TCM).METHODS:The studies concerning TCM courses designed with CBL were included by searching the databases of EBSCO,Pubmed,Science Citation Index,China National Knowledge Infrastructure,Chongqing VIP database.The valid data was extracted in accordance with the included criteria.The quality of the studies was assessed with Gemma Flores-Masteo.RESULTS:A total of 22 articles were retrieved that met the selection criteria:one was of high quality;two were of low quality;the rest were categorized as moderate quality.The majority of the studiesdemonstrated the better effect produced by CBL,while a few studies showed no difference,compared with the didactic format.All included studies confirmed the favorable effect on learners'attitude,skills and ability.CONCLUSION:CBL showed the desirable results in achieving the goal of learning.Compared to didactic approach,it played a more active role in promoting students'competency.Since the quality of the articles on which the study was based was not so high,the findings still need further research to become substantiated.展开更多
Aim： To compare the use of the suprapubic puncture method versus the transurethral method in pressure-flow studies in patients with benign prostatic hyperplasia. Methods： Twenty-three men with benign prostatic hyper...Aim： To compare the use of the suprapubic puncture method versus the transurethral method in pressure-flow studies in patients with benign prostatic hyperplasia. Methods： Twenty-three men with benign prostatic hyperplasia underwent both suprapubic and transurethral pressure-flow studies during a single session. Standard pressure-flow variables were recorded in all patients with both methods, enabling calculation of obstruction using commonly used grading systems, such as the urethral resistance algorithm, the Abrams-Griffith （AG） number and the Schaefer linear nomogram. Results： There were statistically significant differences between the methods in the mean values of maximum flow rate （P 〈 0.05）, detrusor pressure at the maximum flow （P 〈 0.01）, urethral resistance algorithm （P 〈 0.01）, AG number （P 〈 0.01） and maximum cystic capacity （P 〈 0.01）. Of the men in the study, 10 （43.5%） remained in the same Schaefer class with both methods and 18 （78.3%） in the same AG number area. Using the transurethral method, 12 （52.2%） men increased their Schaefer class by one and 1 （4.3%） by two. There were also differences between the suprapubic and transurethral methods using the AG number： 4 （17.4%） men moved from a classification of equivocal to obstructed and 1 （4.3%） from unobstructed to equivocal. Conclusion： The differences between the techniques for measuring intravesical pressure alter the grading of obstruction determined by several of the commonly used classifications. An 8 F transurethral catheter significantly increases the likelihood of a diagnosis of bladder outlet obstruction when compared with the suprapubic method.展开更多
Objective:The integration of training in theory and practice across the medical education spectrum is being encouraged to increase student understanding and skills in the sciences.This study aimed to determine the dec...Objective:The integration of training in theory and practice across the medical education spectrum is being encouraged to increase student understanding and skills in the sciences.This study aimed to determine the deciding factors that drive students'perceived advantages in class to improve precision education and the teaching model.Methods:A mixed strategy of an existing flipped classroom(FC)and a case-based learning(CBL)model was conducted in a medical morphology curriculum for 575 postgraduate students.The subjective learning evaluation of the individuals(learning time,engagement,study interest and concentration,and professional integration)was collected and analyzed after FC-CBL model learning.Results:The results from the general evaluation showed promising results of the medical morphology in the FC-CBL model.Students felt more engaged by instructors in person and benefited in terms of time-saving,flexible arrangements,and professional improvement.Our study contributed to the FC-CBL model in Research Design in postgraduate training in 4 categories:1)advancing a guideline of precision teaching according to individual characteristics;2)revealing whether a learning background is needed for a Research Design course to guide setting up a preliminary course;3)understanding the perceived advantages and their interfaces;and 4)barriers and/or improvement to implement the FC-CBL model in the Research Design class,such as a richer description of e-learning and hands-on practice.Conclusion:Undertaking a FC-CBL combined model could be a useful addition to pedagogy for medical morphology learning in postgraduate training.展开更多
文摘Fixture is an important manufacturing activity. A fixture design system based on case-based reasoning (CBR) is proposed in this paper. A new method of case representation on the basis of fixture function is presented, where the case representation is constituted of workpiece knowledge, processing feature knowledge, and fixture feature knowledge. Running the prototype system shows that the knowledge representation method, using cases, s a better way to transform and explain the design knowledge.
基金supported by the Teaching Reform Project of Stomatology College of Chongqing Medical University(KQJ202215,KQJ202204)the Teaching Reform Project of Chongqing Medical University(JY20220317).
文摘As the most critical part of post-graduate education,the Chinese government launched Standard Resident Training in 2013 to solve the regional inequality of medical quality and meet the increasing social requirement for better medical service.We integrated problem-based learning(PBL)and case-based learning(CBL)in the Endodontics Standard Resident Training.By evaluating with objective parameters including theoretical knowledge and clinical practice skill,and subjective parameters including questionnaire,it was found that PBL+CBL played a positive role in endodontic resident training with a significant difference(P<0.05).This combined training model is instructive for China’s resident training,and this result can provide a rudimentary reference to current postgraduate teaching reform.
基金2023 Higher Education Teaching Research and Reform Project of Southwest Medical University(Project No.:JG2023jdyb033)。
文摘Objective:To explore the effect of implementing the case-based three-dimensional teaching method guided by evidence-based thinking in the teaching of trainee nurses in the rehabilitation department.Method:Eighty nursing practice nurses who were conducting clinical practice learning in the Rehabilitation Department of Deyang People’s Hospital from June 2024 to May 2025 were selected as the research subjects.By using the controlled grouping method,the practice nurses from June 2024 to November 2024 were taken as the control group(n=40).The period from December 2024 to May 2025 was taken as the experimental group(n=40 students),the control group was taught by traditional teaching methods,and the experimental group was taught by evidence-based nursing combined with case teaching method.The clinical thinking ability,autonomous learning ability,exit assessment scores and teaching satisfaction of the two groups of intern nurses at the time of leaving the department were compared.Results:At the time of leaving the department,the scores of each dimension and the total score of clinical thinking ability of the intern nurses in the experimental group were higher than those in the control group(t=9.268,6.354,6.199)9.694,all p<0.05).At the time of leaving the department the scores of each dimension and the total score of the autonomous learning ability of the intern nurses in the experimental group were higher than those in the control group(t=6.998,7.333,5.503,5.977,22.244)all p<0.05).At the time of leaving the department the theoretical assessment scores and operational assessment scores of the experimental group were both higher than those of the control group(t=14.546,11.676,all p<0.05).At the time of graduation,the teaching satisfaction of the experimental group was higher than that of the control group(χ^(2)=7.314,p<0.05.Conclusion:The adoption of the case-based three-dimensional teaching.Rehabilitation method guided by the evidence-based ideology during the teaching process can effectively improve the clinical thinking ability,autonomous learning ability,departmental assessment results and teaching satisfaction of the intern nurses in the rehabilitation department,which is worthy of reference.
基金supported by the China Postdoctoral Science Foundation(Grant No.2021M703366)Shenzhen Science and Technology Program(Grant No.KQTD20190929172835662).
文摘Objective Observational studies have found associations between inflammatory bowel disease(IBD)and the risk of dementia,including Alzheimer’s dementia(AD)and vascular dementia(VD);however,these findings are inconsistent.It remains unclear whether these associations are causal.Methods We conducted a meta-analysis by systematically searching for observational studies on the association between IBD and dementia.Mendelian randomization(MR)analysis based on summary genome-wide association studies(GWASs)was performed.Genetic correlation and Bayesian colocalization analyses were used to provide robust genetic evidence.Results Ten observational studies involving 80,565,688 participants were included in this metaanalysis.IBD was significantly associated with dementia(risk ratio[RR]=1.36,95%CI=1.04-1.78;I2=84.8%)and VD(RR=2.60,95%CI=1.18-5.70;only one study),but not with AD(RR=2.00,95%CI=0.96-4.13;I^(2)=99.8%).MR analyses did not supported significant causal associations of IBD with dementia(dementia:odds ratio[OR]=1.01,95%CI=0.98-1.03;AD:OR=0.98,95%CI=0.95-1.01;VD:OR=1.02,95%CI=0.97-1.07).In addition,genetic correlation and co-localization analyses did not reveal any genetic associations between IBD and dementia.Conclusion Our study did not provide genetic evidence for a causal association between IBD and dementia risk.The increased risk of dementia observed in observational studies may be attributed to unobserved confounding factors or detection bias.
基金Under the auspices of National Natural Science Foundation of China(No.40971060)
文摘Reference values of erythrocyte sedimentation rate(ESR)are the key to interpret ESR blood test in clinic.The common local reference ESR values are more accuracy in blood test that are established with natural geographical factors by using the multiple linear regression(MLR)model and the artificial neural network(ANN).These knowledge-based methods have limitations since the knowledge domains of ESR and natural geographical factors are limited.This paper presents a new cases-depended model to establish reference ESR values with natural geographical factors and location using case-based reasoning(CBR)since knowledge domain of ESR and geographical factors is weak.Overall 224 local normal ESR values of China that calculated from 13623 samples were obtained,and the corresponding natural geographical factors and location that include altitude,sunshine hours,relative humidity,temperature,precipitation,annual temperature range and annual average wind speed were obtained from the National Geomatics Center of China.CBR was used to predict the unseen local reference ESR values with cases.The average absolute deviation(AAD),mean square error(MSE),prediction accuracy(PA),and Pearson correlation coefficient(r)between the observed and estimated data of proposed model is 33.07%,9.02,66.93% and 0.78,which are better than those of ANN and MLR model.The results show that the proposed model provides higher prediction accuracy than those of the artificial neural network and multiple linear regression models.The predicted values are very close to the observed values.Model results show significant agreement of cases data.Consequently,the model is used to predict the unseen local reference ESR with natural geographical factors and location.In spatial,the highest ESR reference areas are distributed in the southern-western district of China that includes Sichuan,Chongqing,Guangxi and Guizhou provinces,and the reference ESR values are greater than 23 mm/60 min.The higher ESR reference values are distributed in the middle part and northern-eastern of China which include Hubei,Henan,Shaanxi,Shanxi,Jilin and Heilongjiang provinces,and the reference ESR values are greater than 18 mm/60min.The lowest ESR reference values are distributed in the northern-western of China that includes Tibet and Xinjiang,and the reference ESR values are lower than 5 mm/60min.
基金supported by“Dalian Maritime University Teaching Reform Research Fund 2022 Annual Project”(Fund No.XJG2022-96).
文摘This paper proposes an interdisciplinary talent training model that combines foreign language education with area studies.The model aims to cultivate international ocean affairs professionals with cross-cultural communication skills,in-depth regional and country knowledge,and practical expertise in ocean affairs.Additionally,the paper presents specific training pathways and policy recommendations for implementing this model.
文摘In modern society,the globalization of literary works is evident,with exceptional literary pieces from various countries spreading worldwide.Among these,children’s literature,due to the specificity of its target audience,imposes distinct requirements on children’s books,compelling translators to approach the text from a child’s perspective.“The Little Prince”has renowned both within and outside of China,and a careful reading of this work can provide us with much inspiration.To this end,the present study adopts the perspective of Gideon Toury’s Descriptive Translation Studies to conduct an in-depth analysis of the different English and Chinese translations in conjunction with the original French novel.This approach aims to better guide literary research and explores translation methods for children’s literature through the analysis of translation norms and rules.
文摘BACKGROUND Gastrointestinal endoscopy technology has significantly improved the diagnostic accuracy and the successful treatment of gastrointestinal diseases.However,a series of ethical issues have emerged,such as expanding treatment indications,which affect the fair distribution of medical resources.There is limited research on ethical issues in the field of digestive endoscopy.AIM To investigate the level of ethical awareness among gastrointestinal endoscopy practitioners and analyze the ethical issues involved in gastrointestinal endoscopy technology.METHODS A questionnaire survey was performed to collect relevant data(gender,age,degree of education,professional title,personnel category,the level of understanding medical ethical principles,ethics training and its learning pathways)from gastrointestinal endoscopy practitioners at the Second Hospital of Dalian Medical University and Dalian Friendship Hospital,including licensed physicians and nurses(including trainees and graduate students).RESULTS The majority of gastrointestinal endoscopy practitioners have received training on ethics,but there is still considerable room for improvement in their ethical awareness.Different learning pathways may affect the mastery of ethical principles, and understanding of ethical principles is more easily achieved through hospital ethics institutions.CONCLUSIONTo address the ethical issues in gastrointestinal endoscopy technology, it is necessary to enhance the humanisticeducation of gastrointestinal endoscopy practitioners, incorporate ethical standards into the technology assessmentprocess, and establish a patient-centered diagnostic and treatment model to improve the ethical awareness of practitionersand achieve a balance between technology and ethics.
文摘To increase the efficiency of the multidisciplinary optimization of aircraft, an aerodynamic approximation model is improved. Based on the study of aerodynamic approximation model constructed by the scaling correction model, case-based reasoning technique is introduced to improve the approximation model for optimization. The aircraft case model is constructed by utilizing the plane parameters related to aerodynamic characteristics as attributes of cases, and the formula of case retrieving is improved. Finally, the aerodynamic approximation model for optimization is improved by reusing the correction factors of the most similar aircraft to the current one. The multidisciplinary optimization of a civil aircraft concept is carried out with the improved aerodynamic approximation model. The results demonstrate that the precision and the efficiency of the optimization can be improved by utilizing the improved aerodynamic approximation model with ease-based reasoning technique.
文摘Through the questionnaire survey and comparative studies on tourist satisfaction of tourism services among three world heritage sites,i.e.Huangshan Mountain,Lushan Mountain and Wuyi Mountain,this study pointed out the problems in tourism services of three scenic areas and then put forward relevant countermeasures for the management of scenic areas.
基金This project is supported by National Natural Science Foundation of China(No.50275133) and China Hi-tech Program CIMS Topic (No.2003-China(No.50275133) and China Hi-tech Program CIMS Topic (No.2003-AA411320). Received July 22, 2003
文摘The increasing complexity and size of configuration knowledge bases requres the provisionof advanced methods supporting the development of the actual configuration process and design reuse.A new framework to find a feasible and practical product configuration method is presented in masscustomization. The basic idea of the appoach is to integrate case-based reasoning (CBR) with a con-straint satisfaction problem(CSP). The similarity measure between a crisp and range is also given,which is common in case retrieves. Based on the configuration model, a product platform and customerneeds, case adaptation is carried out with the repair-based algorithm. Lastly, the methodology in theelevator configuration design domain is tested.
基金financially supported by the National Key Technology R&D Program in the 11th Five-Years Plan of China (No.2006BAE03A07)Fundamental Research Funds for the Central Universities (No.FRF-TP12-086A)
文摘An improved case-based reasoning （CBR） method was proposed to predict the endpoint temperature of molten steel in Ruhrstahl Heraeus （RH） process. Firstly, production data were analyzed by multiple linear regressions and a pairwise comparison matrix in analytic hierarchy process （AHP） was determined by this linear regression＇s coefficient. The weights of various influencing factors were obtained by AHP. Secondly, the dividable principles of case base including ＂0-1＂ and ＂breakpoint＂ were proposed, and the case base was divided into several homogeneous parts. Finally, the improved CBR was compared with ordinary CBR, which is based on the even weight and the single base. The results show that the improved CBR has a higher hit rate for predicting the endpoint temperature of molten steel in RH.
基金This project is supported by National Hi-tech Research and Development Program of China (863 Program, Grant No. 2008AA04Z115)Science and Technology Program of the Ministry of Construction of China (Grant No. 2008-K8-2)+1 种基金Jiangsu Provincial Natural Science Foundation of China (Grant No. BK2007042)Open Fund of State Key Lab of CAD&CG, Zhejiang University, China (Grant No. A0914)
文摘The design of the two-step gear reducer is a tedious and time-consuming process. For the purpose of improving the efficiency and intelligence of design process, case-based reasoning（CBR） technology was applied to the design of the two-step gear reducer. Firstly, the current design method for the two-step gear reducer was analyzed and the principle of CBR was described. Secondly, according to the characteristics of the reducer, three key technologies of CBR were studied and the corresponding methods were provided, which are as follows： （a） an object-oriented knowledge representation method, （b） a retrieval method combining the nearest neighbor with the induction indexing, and （c） a case adaptation algorithm combining the revision based on rule with artificial revision. Also, for the purpose of improving the credibility of case retrieval, a new method for determining the weights of characteristics and a similarity formula were presented, which is a combinatorial weighting method with the analytic hierarchy process（AHP） and roughness set theory. Lastly, according to the above analytic results, a design system of the two-step gear reducer on CBR was developed by VC＋＋, UG and Access 2003. A new method for the design of the two-step gear reducer is provided in this study. If the foregoing developed system is applied to design the two-step gear reducer, design efficiency is improved, which enables the designer to release from the tedious design process of the gear reducer so as to put more efforts on innovative design. The study result fully reflects the feasibility and validity of CBR technology in the process of the design of the mechanical parts.
基金This project is support by National Natural Science Foundation of China(No.59990470)National High Technology Research and Development Program of China (No.2001AA415330).
文摘The current method of case-based design (CBD) can be well practiced forconfiguration design in which design experience knowledge is involved. However, since the designcase is confined to a certain application domain, it is difficult for CBD to be applied toconceptual design process that develops concepts to meet design specifications. Firstly, a functionfactor description space is erected to provide an exhibition room for all functions of design cases.Next, the approach for identifying the space state of function factor in description space isproposed, including the determination of the similarities between function factors of design case.And then a general object-oriented representation for design case is presented by bringing the classof function and in-out flow into the current case representation. Finally, a living example forelectro-pet design that illustrates the implementation of the method for case-based conceptualdesign based on distributed design case repositories is described.
基金supported by grants from the National Natural Science Foundation of China(41431177 and 41871300)the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD),China+4 种基金the Innovation Project of State Key Laboratory of Resources and Environmental Information System(LREIS),China(O88RA20CYA)the Outstanding Innovation Team in Colleges and Universities in Jiangsu Province,ChinaSupports to A-Xing Zhu through the Vilas Associate Awardthe Hammel Faculty Fellow Awardthe Manasse Chair Professorship from the University of Wisconsin-Madison。
文摘Selecting a proper set of covariates is one of the most important factors that influence the accuracy of digital soil mapping(DSM).The statistical or machine learning methods for selecting DSM covariates are not available for those situations with limited samples.To solve the problem,this paper proposed a case-based method which could formalize the covariate selection knowledge contained in practical DSM applications.The proposed method trained Random Forest(RF)classifiers with DSM cases extracted from the practical DSM applications and then used the trained classifiers to determine whether each one potential covariate should be used in a new DSM application.In this study,we took topographic covariates as examples of covariates and extracted 191 DSM cases from 56 peer-reviewed journal articles to evaluate the performance of the proposed case-based method by Leave-One-Out cross validation.Compared with a novices’commonly-used way of selecting DSM covariates,the proposed case-based method improved more than 30%accuracy according to three quantitative evaluation indices(i.e.,recall,precision,and F1-score).The proposed method could be also applied to selecting the proper set of covariates for other similar geographical modeling domains,such as landslide susceptibility mapping,and species distribution modeling.
基金financially supported by National Key Research and Development Program of China(No.2016YFB0601301)National Natural Science Foundation of China(No.51574032)Fundamental Research Funds for the Central Universities(No.FRF-TP-16-081A1).
文摘Temperature control is the key of Ruhrstahl-Heraeus (RH) process in steelmaking plant. The accuracy of RH control model greatly affects the molten steel temperature fluctuation. To obtain RH control model with higher accuracy, an improved case-based reasoning (CBR) model based on attribute weights optimized by genetic algorithm (GA) was proposed. The fitness function in GA was determined according to the prediction accuracy of end temperature of molten steel in RH;then, GA is used to optimize all the attribute weights based on known case base. An improved CBR model that contains the optimized attribute weights was applied to predict end temperature of molten steel in RH, and the prediction accuracy wascalculated. Four methods, CBR based on attribute weights optimized by GA (CBR-GA), ordinary CBR, back propagation neural network (BPNN) and multiple linear regression (MLR) method were employed for comparison. The results show that in the error range of [- 3 ℃, 3 ℃],[- 5 ℃, 5 ℃],[- 7 ℃, 7 ℃] and [- 10 ℃, 10 ℃], the prediction accuracy of CBR-GA was improved by 19.99%, 28.19%, 27.11% and 16.3%, respectively, than that of MLR. Compared with BPNN, the prediction accuracy increased by 3.22%, 7.44%, 5.29% and 2.40%, respectively. Compared with ordinary CBR, the accuracy increased by 5.43%, 5.80%, 4.66% and 2.27%, respectively.
基金Supported by "Twelve-five" Scientific Research Study on Education from Chinese Academy of Higher Education(No.11YB032)by Scientific Research Study on Education from Sichuan Academy of Higher Education(No.11SC-007)by Key research project on teaching reform from Chengdu University of Traditional Chinese Medicine(No.JGZD201001)
文摘OBJECTIVE:To assess the effect of case-based learning(CBL)in the education of Traditional Chinese Medicine(TCM).METHODS:The studies concerning TCM courses designed with CBL were included by searching the databases of EBSCO,Pubmed,Science Citation Index,China National Knowledge Infrastructure,Chongqing VIP database.The valid data was extracted in accordance with the included criteria.The quality of the studies was assessed with Gemma Flores-Masteo.RESULTS:A total of 22 articles were retrieved that met the selection criteria:one was of high quality;two were of low quality;the rest were categorized as moderate quality.The majority of the studiesdemonstrated the better effect produced by CBL,while a few studies showed no difference,compared with the didactic format.All included studies confirmed the favorable effect on learners'attitude,skills and ability.CONCLUSION:CBL showed the desirable results in achieving the goal of learning.Compared to didactic approach,it played a more active role in promoting students'competency.Since the quality of the articles on which the study was based was not so high,the findings still need further research to become substantiated.
文摘Aim： To compare the use of the suprapubic puncture method versus the transurethral method in pressure-flow studies in patients with benign prostatic hyperplasia. Methods： Twenty-three men with benign prostatic hyperplasia underwent both suprapubic and transurethral pressure-flow studies during a single session. Standard pressure-flow variables were recorded in all patients with both methods, enabling calculation of obstruction using commonly used grading systems, such as the urethral resistance algorithm, the Abrams-Griffith （AG） number and the Schaefer linear nomogram. Results： There were statistically significant differences between the methods in the mean values of maximum flow rate （P 〈 0.05）, detrusor pressure at the maximum flow （P 〈 0.01）, urethral resistance algorithm （P 〈 0.01）, AG number （P 〈 0.01） and maximum cystic capacity （P 〈 0.01）. Of the men in the study, 10 （43.5%） remained in the same Schaefer class with both methods and 18 （78.3%） in the same AG number area. Using the transurethral method, 12 （52.2%） men increased their Schaefer class by one and 1 （4.3%） by two. There were also differences between the suprapubic and transurethral methods using the AG number： 4 （17.4%） men moved from a classification of equivocal to obstructed and 1 （4.3%） from unobstructed to equivocal. Conclusion： The differences between the techniques for measuring intravesical pressure alter the grading of obstruction determined by several of the commonly used classifications. An 8 F transurethral catheter significantly increases the likelihood of a diagnosis of bladder outlet obstruction when compared with the suprapubic method.
基金supported by grants from the Hunan Province Academic Degree and Graduate Education Reform Project(No.2020JGYB028)the National Natural Science Foundation of China(No.81971891,No.82172196,No.81772134)+1 种基金the Key Laboratory of Emergency and Trauma(Hainan Medical University)of the Ministry of Education(No.KLET-202108)the College Students'Innovation and Entrepreneurship Project(No.S20210026020013).
文摘Objective:The integration of training in theory and practice across the medical education spectrum is being encouraged to increase student understanding and skills in the sciences.This study aimed to determine the deciding factors that drive students'perceived advantages in class to improve precision education and the teaching model.Methods:A mixed strategy of an existing flipped classroom(FC)and a case-based learning(CBL)model was conducted in a medical morphology curriculum for 575 postgraduate students.The subjective learning evaluation of the individuals(learning time,engagement,study interest and concentration,and professional integration)was collected and analyzed after FC-CBL model learning.Results:The results from the general evaluation showed promising results of the medical morphology in the FC-CBL model.Students felt more engaged by instructors in person and benefited in terms of time-saving,flexible arrangements,and professional improvement.Our study contributed to the FC-CBL model in Research Design in postgraduate training in 4 categories:1)advancing a guideline of precision teaching according to individual characteristics;2)revealing whether a learning background is needed for a Research Design course to guide setting up a preliminary course;3)understanding the perceived advantages and their interfaces;and 4)barriers and/or improvement to implement the FC-CBL model in the Research Design class,such as a richer description of e-learning and hands-on practice.Conclusion:Undertaking a FC-CBL combined model could be a useful addition to pedagogy for medical morphology learning in postgraduate training.
