Due to the study of the function of heart and aoritic valve, we set up a physicalmodel of left ventricle, aortic valve and afterload and derive theoretical equation of each part from the model. Then we calculate the h...Due to the study of the function of heart and aoritic valve, we set up a physicalmodel of left ventricle, aortic valve and afterload and derive theoretical equation of each part from the model. Then we calculate the hasic equations within phystology and impair parameters. Bwsed on this, we will discus fully in the next paper the effectofleyt ventricular afterloadon valve opining, ejection and valve Jumction .etc展开更多
Introduction: Left Ventricle Postinfarction Pseudoaneurysm (LVPS)—false aneurysm occurs after a free-wall rupture contained by the adjacent pericardium. LVPS lacks the normal structure of the ventricular wall and dis...Introduction: Left Ventricle Postinfarction Pseudoaneurysm (LVPS)—false aneurysm occurs after a free-wall rupture contained by the adjacent pericardium. LVPS lacks the normal structure of the ventricular wall and disrupts the normal chamber anatomy. However, the natural history, clinical presentation and surgical outcome are still unclear. For that reason, it is necessary to describe the most relevant anatomical characteristics of LVPS and the appropriate surgical strategies currently applied. Methods: We reviewed the anatomical characteristics of several patients diagnosed of LVPS and the surgical technique performed. In this work two different anatomical types of LVPS are described in detail, with the surgical and structural implications for left ventricle reconstruction. Results: There are two different anatomical forms of LVPS: 1) Typical pseudoaneurysm, with a small gateway neck between the Left Ventricle and the false aneurysm chamber (Figure 1(A));2) Atypical pseudoaneurysm, in which the anatomical defect is bigger, without well-defined edges, extends over a large segment of infarcted and thinned myocardial tissue. In both cases, the therapeutics targets and the surgical techniques used were directed to restore the normal geometry of Left Ventricle, keeping the optimal mitral valve function. Conclusions: The surgical key-step is to preserve or to remodel the ventricular chamber anatomy. This fact restores the ventricular geometry, not only removing the wall discontinuity that generated the pseudoaneurysm. Nevertheless, final prognosis depends on the underlying ischemic cardiomyopathy and mechanical complications, such us mitral regurgitation or ventricular septal defect.展开更多
<strong>Background:</strong><span style="font-family:Verdana;"> Heart failure is the commonest cardiovascular complication in type 2 diabetes mellitus. However, subclinical left ventricular...<strong>Background:</strong><span style="font-family:Verdana;"> Heart failure is the commonest cardiovascular complication in type 2 diabetes mellitus. However, subclinical left ventricular dysfunction can’t be detected using 2D echocardiography which </span><span style="font-family:Verdana;">is </span><span style="font-family:;" "=""><span style="font-family:Verdana;">routinely used for cardiac evaluation of diabetic patients. We aimed to determine the prevalence and factors associated to left ventricular global longitudinal strain (LV GLS) impairment in type 2 diabetes Cameroonians patients. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> We conducted a cross-sectional study from January 2019 to June 2019, including type 2 diabetes patients with preserved left ventricle ejection fraction. Clinical and echocardiographic data were collected, and LV GLS was assessed using speckle tracking technique, a value ≤</span></span><span style="font-family:Verdana;"> -</span><span style="font-family:;" "=""><span style="font-family:Verdana;">16% been considered as normal value. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> We recruited 95 patients, with a mean age of 57.4 ± 11.8 years old and median diabetes duration of 5 [2 </span></span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;"> 12] years. Echocardiographic evaluation found 56.3% of left ventricle remodelling, 51.6% of left ventricle diastolic dysfunction and mean left ventricle ejection of 63.3</span><span style="font-family:Verdana;">%</span><span style="font-family:Verdana;"> ± 6.6%. LV GLS impairment was present in 43.2% (95% CI: 32.6 </span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;"> 53.7) of the participants. After adjustment to all significantly associated factors, Obesity (aOR: 4;95% CI: 1.5 </span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;"> 10.6) and diastolic dysfunction (aOR: 3.1;95% CI: 1.2 </span><span style="font-family:Verdana;">-</span><span style="font-family:;" "=""><span style="font-family:Verdana;"> 8.2) were independent factors associated with LV GLS. </span><b><span style="font-family:Verdana;">Conclusions:</span></b><span style="font-family:Verdana;"> Subclinical systolic dysfunction assessed by LV GLS impairment is frequent in diabetic patients. Further research should be carried out more extensively to integrate LV GLS in the type 2 diabetes patients’ routine follow up for a better prognostic outcome, especially in low-incomes countries.</span></span>展开更多
Cardiovascular magnetic resonance (CMR) has become a reference standard for the measure-ment of cardiac volumes, function, and mass. This study aims to reconstruct three dimen-sional modeling of the left ventricle (LV...Cardiovascular magnetic resonance (CMR) has become a reference standard for the measure-ment of cardiac volumes, function, and mass. This study aims to reconstruct three dimen-sional modeling of the left ventricle (LV) in pa-tients with heart failure (HF) using CMRtools and thereby derive the LV functional indices. CMR images were acquired in 41 subjects (6 females) with heart failure (HF) and 12 normal controls (4 females). Five comparisons were made (i) nor-mal and dilated heart failure subjects, (ii) male and female normal heart, (iii) male and female dilated heart, (iv) male normal and dilated heart failure and (v) female normal and dilated heart failure. In HF, a significant higher values of EDV (320 刡 79 vs. 126 刡 22 ml, P&amp;amp;amp;amp;lt;0.0001), ESV (255 刡 68 vs. 54 刡 12 ml, P&amp;amp;amp;amp;lt;0.00001) and lower values of EF (20 刡 7 vs. 58 刡 5 %) were found compared that of normal control. There were significant difference on LV EDV and ESV between sex in both normal and HF subjects.展开更多
目的探讨射频消融(RFCA)治疗频发室性早搏后左室功能和结构的变化。方法收集2006年1月—2011年8月成功行射频消融治疗的频发室性早搏病例59例。比较手术前、后NYHA心功能分级及超声心动图LVEF、LVEDD、LVESD、IVSd、LVPWd等参数的变化...目的探讨射频消融(RFCA)治疗频发室性早搏后左室功能和结构的变化。方法收集2006年1月—2011年8月成功行射频消融治疗的频发室性早搏病例59例。比较手术前、后NYHA心功能分级及超声心动图LVEF、LVEDD、LVESD、IVSd、LVPWd等参数的变化。结果与术前比较,成功消融根治室性早搏后,患者胸闷、心悸症状缓解,NYHA心功能分级明显好转(P<0.05),超声心动图各参数均明显缩小(LVEDD 51.2 mm±4.9 mm vs44.3 mm±4.2 mm,P<0.05,LVESD 32.8 mm±5.1 mm vs 27.2 mm±3.5 mm,P<0.05,IVSd 8.9 mm±0.8 nn vs7.5 mm±0.9 mm,P<0.05,LVPWd 8.8 mm±0.9 mm vs 7.5 mm±0.9 mm,P<0.05);LVEF显著提高(0.64±0.12vs 0.71±0.07,P<0.05)。结论 RFCA是改善频发室性早搏患者症状、心脏结构及功能状况的有效方法。展开更多
文摘Due to the study of the function of heart and aoritic valve, we set up a physicalmodel of left ventricle, aortic valve and afterload and derive theoretical equation of each part from the model. Then we calculate the hasic equations within phystology and impair parameters. Bwsed on this, we will discus fully in the next paper the effectofleyt ventricular afterloadon valve opining, ejection and valve Jumction .etc
文摘Introduction: Left Ventricle Postinfarction Pseudoaneurysm (LVPS)—false aneurysm occurs after a free-wall rupture contained by the adjacent pericardium. LVPS lacks the normal structure of the ventricular wall and disrupts the normal chamber anatomy. However, the natural history, clinical presentation and surgical outcome are still unclear. For that reason, it is necessary to describe the most relevant anatomical characteristics of LVPS and the appropriate surgical strategies currently applied. Methods: We reviewed the anatomical characteristics of several patients diagnosed of LVPS and the surgical technique performed. In this work two different anatomical types of LVPS are described in detail, with the surgical and structural implications for left ventricle reconstruction. Results: There are two different anatomical forms of LVPS: 1) Typical pseudoaneurysm, with a small gateway neck between the Left Ventricle and the false aneurysm chamber (Figure 1(A));2) Atypical pseudoaneurysm, in which the anatomical defect is bigger, without well-defined edges, extends over a large segment of infarcted and thinned myocardial tissue. In both cases, the therapeutics targets and the surgical techniques used were directed to restore the normal geometry of Left Ventricle, keeping the optimal mitral valve function. Conclusions: The surgical key-step is to preserve or to remodel the ventricular chamber anatomy. This fact restores the ventricular geometry, not only removing the wall discontinuity that generated the pseudoaneurysm. Nevertheless, final prognosis depends on the underlying ischemic cardiomyopathy and mechanical complications, such us mitral regurgitation or ventricular septal defect.
文摘<strong>Background:</strong><span style="font-family:Verdana;"> Heart failure is the commonest cardiovascular complication in type 2 diabetes mellitus. However, subclinical left ventricular dysfunction can’t be detected using 2D echocardiography which </span><span style="font-family:Verdana;">is </span><span style="font-family:;" "=""><span style="font-family:Verdana;">routinely used for cardiac evaluation of diabetic patients. We aimed to determine the prevalence and factors associated to left ventricular global longitudinal strain (LV GLS) impairment in type 2 diabetes Cameroonians patients. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> We conducted a cross-sectional study from January 2019 to June 2019, including type 2 diabetes patients with preserved left ventricle ejection fraction. Clinical and echocardiographic data were collected, and LV GLS was assessed using speckle tracking technique, a value ≤</span></span><span style="font-family:Verdana;"> -</span><span style="font-family:;" "=""><span style="font-family:Verdana;">16% been considered as normal value. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> We recruited 95 patients, with a mean age of 57.4 ± 11.8 years old and median diabetes duration of 5 [2 </span></span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;"> 12] years. Echocardiographic evaluation found 56.3% of left ventricle remodelling, 51.6% of left ventricle diastolic dysfunction and mean left ventricle ejection of 63.3</span><span style="font-family:Verdana;">%</span><span style="font-family:Verdana;"> ± 6.6%. LV GLS impairment was present in 43.2% (95% CI: 32.6 </span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;"> 53.7) of the participants. After adjustment to all significantly associated factors, Obesity (aOR: 4;95% CI: 1.5 </span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;"> 10.6) and diastolic dysfunction (aOR: 3.1;95% CI: 1.2 </span><span style="font-family:Verdana;">-</span><span style="font-family:;" "=""><span style="font-family:Verdana;"> 8.2) were independent factors associated with LV GLS. </span><b><span style="font-family:Verdana;">Conclusions:</span></b><span style="font-family:Verdana;"> Subclinical systolic dysfunction assessed by LV GLS impairment is frequent in diabetic patients. Further research should be carried out more extensively to integrate LV GLS in the type 2 diabetes patients’ routine follow up for a better prognostic outcome, especially in low-incomes countries.</span></span>
文摘Cardiovascular magnetic resonance (CMR) has become a reference standard for the measure-ment of cardiac volumes, function, and mass. This study aims to reconstruct three dimen-sional modeling of the left ventricle (LV) in pa-tients with heart failure (HF) using CMRtools and thereby derive the LV functional indices. CMR images were acquired in 41 subjects (6 females) with heart failure (HF) and 12 normal controls (4 females). Five comparisons were made (i) nor-mal and dilated heart failure subjects, (ii) male and female normal heart, (iii) male and female dilated heart, (iv) male normal and dilated heart failure and (v) female normal and dilated heart failure. In HF, a significant higher values of EDV (320 刡 79 vs. 126 刡 22 ml, P&amp;amp;amp;amp;lt;0.0001), ESV (255 刡 68 vs. 54 刡 12 ml, P&amp;amp;amp;amp;lt;0.00001) and lower values of EF (20 刡 7 vs. 58 刡 5 %) were found compared that of normal control. There were significant difference on LV EDV and ESV between sex in both normal and HF subjects.
文摘目的探讨射频消融(RFCA)治疗频发室性早搏后左室功能和结构的变化。方法收集2006年1月—2011年8月成功行射频消融治疗的频发室性早搏病例59例。比较手术前、后NYHA心功能分级及超声心动图LVEF、LVEDD、LVESD、IVSd、LVPWd等参数的变化。结果与术前比较,成功消融根治室性早搏后,患者胸闷、心悸症状缓解,NYHA心功能分级明显好转(P<0.05),超声心动图各参数均明显缩小(LVEDD 51.2 mm±4.9 mm vs44.3 mm±4.2 mm,P<0.05,LVESD 32.8 mm±5.1 mm vs 27.2 mm±3.5 mm,P<0.05,IVSd 8.9 mm±0.8 nn vs7.5 mm±0.9 mm,P<0.05,LVPWd 8.8 mm±0.9 mm vs 7.5 mm±0.9 mm,P<0.05);LVEF显著提高(0.64±0.12vs 0.71±0.07,P<0.05)。结论 RFCA是改善频发室性早搏患者症状、心脏结构及功能状况的有效方法。
