The possibility of formation of complexes between glycine and boron doped C60 （C59B） fullerene is investigated and compared with that of C60 fullerene by using the density functional theory calculations. It has been...The possibility of formation of complexes between glycine and boron doped C60 （C59B） fullerene is investigated and compared with that of C60 fullerene by using the density functional theory calculations. It has been found that the binding of glycine to C59B generated the most stable complexes via its carbonyl oxygen active site, with a binding energy of-37.89 kcal/mol, while the glycine molecule prefers to bind to the pure C60 cage via its amino nitrogen active site, consistent with the recent experimental and theoretical studies. We have also tested the stability of the most stable Gly-C59B complex with ab initio molecular dynamics simulation, carried out at room temperature. These indicate that the B-doped C60 fullerenes seem to be more suitable materials for bindings to proteins than pure C60 fullerenes.展开更多
The polarizabilities of DNA in transverse direction and CdSe semiconductor quantum dots （QDs） deposited on mica surface are compared by means of electrostatic force microscopy （EFM）. We observe clear EFM-phase shi...The polarizabilities of DNA in transverse direction and CdSe semiconductor quantum dots （QDs） deposited on mica surface are compared by means of electrostatic force microscopy （EFM）. We observe clear EFM-phase shift over CdSe QDs, while no obvious signal on DNA is detected, suggesting that DNA molecules is an electrical insulator.展开更多
Flexible electronic skins hold great promise for biomedical applications,although challenges remain in achieving controllable interactions with the biological interface and accurate signal collection.Inspired by octop...Flexible electronic skins hold great promise for biomedical applications,although challenges remain in achieving controllable interactions with the biological interface and accurate signal collection.Inspired by octopuses and chameleons,we propose a novel electronic skin paradigm with on-demand adhesion and opto-electronic synergistic display capabilities.Our electronic skins are composed of a stretchable polyurethane(PU)inverse opal film integrated with a carbon nanotube(CNT)-hybridized polyacrylamide(PAAm)-gelatin double-network-hydrogel conductive flexible substrate and a temperature-responsive poly(N-isopropylacrylamide)(PNIPAm)octopus-inspired hemispherical adhesive array.The device’s CNT hybrid double-network provides robust and sensitive monitoring of temperature and motion.Meanwhile,its flexible PU layer with an inverse opal structure allows for visual motion color sensing.Integrated neural network processing ensures accurate,wide-range,and independent multimodal display.Additionally,the integration of the photothermal effect of CNTs and the temperaturesensitive octopus-inspired PNIPAm adhesive array enables on-demand adhesion.The sensing and adhesion demonstrations ex vivo and in vivo showcase the proposed flexible electronic skin’s inspirational design and functional utilities.The potential applications of such a versatile device are vast,ranging from healthcare to human-machine interactions.展开更多
Organic electrochemical transistors(OECTs),essential components in bioelectronics,serve as a bridge between biological systems and electronic interfaces by converting ionic signals into electronic currents,making them...Organic electrochemical transistors(OECTs),essential components in bioelectronics,serve as a bridge between biological systems and electronic interfaces by converting ionic signals into electronic currents,making them crucial for applications like implantable biosensors,wearable health monitors,and neuromorphic computing architectures[1,2].Despite their ability to bind directly to biological fluids and tissues,and excellent conformal interfaces with dynamic surfaces such as human skin,due to repeated electrochemical cycling,exposure to environmental factors,and parasitic reactions,OECTs still face persistent stability issues that often manifest as hysteresis in device performance,continuously limiting their potential for long-term bioelectronic applications[3,4].Therefore,addressing this instability is crucial to unlocking the full potential of OECTs in chronic medical monitoring,adaptive biohybrid systems,and energy-efficient neuromorphic hardware.展开更多
Current stretchable surface electrodes have attracted increasing attention owing to their potential applications in biological signal monitoring, wearable human-machine interfaces（HMIs） and the Internet of Things. T...Current stretchable surface electrodes have attracted increasing attention owing to their potential applications in biological signal monitoring, wearable human-machine interfaces（HMIs） and the Internet of Things. The paper proposed a stretchable HMI based on a surface electromyography（sEMG） electrode with a self-similar serpentine configuration. The sEMG electrode was transfer-printed onto the skin surface conformally to monitor biological signals, followed by signal classification and controlling of a mobile robot. Such electrodes can bear rather large deformation（such as 〉30%） under an appropriate areal coverage. The sEMG electrodes have been used to record electrophysiological signals from different parts of the body with sharp curvature, such as the index finger,back of the neck and face, and they exhibit great potential for HMI in the fields of robotics and healthcare. The electrodes placed onto the two wrists would generate two different signals with the fist clenched and loosened. It is classified to four kinds of signals with a combination of the gestures from the two wrists, that is, four control modes. Experiments demonstrated that the electrodes were successfully used as an HMI to control the motion of a mobile robot remotely.展开更多
文摘The possibility of formation of complexes between glycine and boron doped C60 （C59B） fullerene is investigated and compared with that of C60 fullerene by using the density functional theory calculations. It has been found that the binding of glycine to C59B generated the most stable complexes via its carbonyl oxygen active site, with a binding energy of-37.89 kcal/mol, while the glycine molecule prefers to bind to the pure C60 cage via its amino nitrogen active site, consistent with the recent experimental and theoretical studies. We have also tested the stability of the most stable Gly-C59B complex with ab initio molecular dynamics simulation, carried out at room temperature. These indicate that the B-doped C60 fullerenes seem to be more suitable materials for bindings to proteins than pure C60 fullerenes.
基金Supported by the National Natural Science Foundation under Grant No 10604034, the Natural Science Foundation of Zhejiang Province （Y606309）, Ningbo Natural Science Foundation （2006A610046）, and K. C. Wong Magna Fund in Ningbo University.
文摘The polarizabilities of DNA in transverse direction and CdSe semiconductor quantum dots （QDs） deposited on mica surface are compared by means of electrostatic force microscopy （EFM）. We observe clear EFM-phase shift over CdSe QDs, while no obvious signal on DNA is detected, suggesting that DNA molecules is an electrical insulator.
基金supported by the National Key Research and Development Program of China(2022YFB4700100)the National Natural Science Foundation of China(T2225003,52073060,81930048,82330061,and 61927805)+4 种基金the Nanjing Medical Science and Tech-nique Development Foundation(ZKX21019)the Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program(2019BT02X105)the Hong Kong Research Grant Council General Research Fund(15217721 and 15125724)the Shenzhen Science and Technology Innovation Commission(JCYJ20220818100202005)the Hong Kong PolytechnicUniversity Fund(P0045680,P0043485,P0045762,and P0049101)。
文摘Flexible electronic skins hold great promise for biomedical applications,although challenges remain in achieving controllable interactions with the biological interface and accurate signal collection.Inspired by octopuses and chameleons,we propose a novel electronic skin paradigm with on-demand adhesion and opto-electronic synergistic display capabilities.Our electronic skins are composed of a stretchable polyurethane(PU)inverse opal film integrated with a carbon nanotube(CNT)-hybridized polyacrylamide(PAAm)-gelatin double-network-hydrogel conductive flexible substrate and a temperature-responsive poly(N-isopropylacrylamide)(PNIPAm)octopus-inspired hemispherical adhesive array.The device’s CNT hybrid double-network provides robust and sensitive monitoring of temperature and motion.Meanwhile,its flexible PU layer with an inverse opal structure allows for visual motion color sensing.Integrated neural network processing ensures accurate,wide-range,and independent multimodal display.Additionally,the integration of the photothermal effect of CNTs and the temperaturesensitive octopus-inspired PNIPAm adhesive array enables on-demand adhesion.The sensing and adhesion demonstrations ex vivo and in vivo showcase the proposed flexible electronic skin’s inspirational design and functional utilities.The potential applications of such a versatile device are vast,ranging from healthcare to human-machine interactions.
文摘Organic electrochemical transistors(OECTs),essential components in bioelectronics,serve as a bridge between biological systems and electronic interfaces by converting ionic signals into electronic currents,making them crucial for applications like implantable biosensors,wearable health monitors,and neuromorphic computing architectures[1,2].Despite their ability to bind directly to biological fluids and tissues,and excellent conformal interfaces with dynamic surfaces such as human skin,due to repeated electrochemical cycling,exposure to environmental factors,and parasitic reactions,OECTs still face persistent stability issues that often manifest as hysteresis in device performance,continuously limiting their potential for long-term bioelectronic applications[3,4].Therefore,addressing this instability is crucial to unlocking the full potential of OECTs in chronic medical monitoring,adaptive biohybrid systems,and energy-efficient neuromorphic hardware.
基金supported by the National Natural Science Foundation of China(Nos.51635007,91323303)
文摘Current stretchable surface electrodes have attracted increasing attention owing to their potential applications in biological signal monitoring, wearable human-machine interfaces（HMIs） and the Internet of Things. The paper proposed a stretchable HMI based on a surface electromyography（sEMG） electrode with a self-similar serpentine configuration. The sEMG electrode was transfer-printed onto the skin surface conformally to monitor biological signals, followed by signal classification and controlling of a mobile robot. Such electrodes can bear rather large deformation（such as 〉30%） under an appropriate areal coverage. The sEMG electrodes have been used to record electrophysiological signals from different parts of the body with sharp curvature, such as the index finger,back of the neck and face, and they exhibit great potential for HMI in the fields of robotics and healthcare. The electrodes placed onto the two wrists would generate two different signals with the fist clenched and loosened. It is classified to four kinds of signals with a combination of the gestures from the two wrists, that is, four control modes. Experiments demonstrated that the electrodes were successfully used as an HMI to control the motion of a mobile robot remotely.
