This paper delves into the baseline design under the baseline parameterization model in experimental design, focusing on the relationship between the K-aberration criterion and the word length pattern (WLP) of regular...This paper delves into the baseline design under the baseline parameterization model in experimental design, focusing on the relationship between the K-aberration criterion and the word length pattern (WLP) of regular two-level designs. The paper provides a detailed analysis of the relationship between K5and the WLP for regular two-level designs with resolution t=3, and proposes corresponding theoretical results. These results not only theoretically reveal the connection between the orthogonal parameterization model and the baseline parameterization model but also provide theoretical support for finding the K-aberration optimal regular two-level baseline designs. It demonstrates how to apply these theories to evaluate and select the optimal experimental designs. In practical applications, experimental designers can utilize the theoretical results of this paper to quickly assess and select regular two-level baseline designs with minimal K-aberration by analyzing the WLP of the experimental design. This allows for the identification of key factors that significantly affect the experimental outcomes without frequently changing the factor levels, thereby maximizing the benefits of the experiment.展开更多
The natural visibility graph method has been widely used in physiological signal analysis,but it fails to accurately handle signals with data points below the baseline.Such signals are common across various physiologi...The natural visibility graph method has been widely used in physiological signal analysis,but it fails to accurately handle signals with data points below the baseline.Such signals are common across various physiological measurements,including electroencephalograph(EEG)and functional magnetic resonance imaging(fMRI),and are crucial for insights into physiological phenomena.This study introduces a novel method,the baseline perspective visibility graph(BPVG),which can analyze time series by accurately capturing connectivity across data points both above and below the baseline.We present the BPVG construction process and validate its performance using simulated signals.Results demonstrate that BPVG accurately translates periodic,random,and fractal signals into regular,random,and scale-free networks respectively,exhibiting diverse degree distribution traits.Furthermore,we apply BPVG to classify Alzheimer’s disease(AD)patients from healthy controls using EEG data and identify non-demented adults at varying dementia risk using resting-state fMRI(rs-fMRI)data.Utilizing degree distribution entropy derived from BPVG networks,our results exceed the best accuracy benchmark(77.01%)in EEG analysis,especially at channels F4(78.46%)and O1(81.54%).Additionally,our rs-fMRI analysis achieves a statistically significant classification accuracy of 76.74%.These findings highlight the effectiveness of BPVG in distinguishing various time series types and its practical utility in EEG and rs-fMRI analysis for early AD detection and dementia risk assessment.In conclusion,BPVG’s validation across both simulated and real data confirms its capability to capture comprehensive information from time series,irrespective of baseline constraints,providing a novel method for studying neural physiological signals.展开更多
Toroidal torques,generated by the resonant magnetic perturbation(RMP)and acting on the plasma column,are numerically systematically investigated for an ITER baseline scenario.The neoclassical toroidal viscosity(NTV),i...Toroidal torques,generated by the resonant magnetic perturbation(RMP)and acting on the plasma column,are numerically systematically investigated for an ITER baseline scenario.The neoclassical toroidal viscosity(NTV),in particular the resonant portion,is found to provide the dominant contribution to the total toroidal torque under the slow plasma flow regime in ITER.While the electromagnetic torque always opposes the plasma flow,the toroidal torque associated with the Reynolds stress enhances the plasma flow independent of the flow direction.A peculiar double-peak structure for the net NTV torque is robustly computed for ITER,as the toroidal rotation frequency is scanned near the zero value.This structure is found to be ultimately due to a non-monotonic behavior of the wave-particle resonance integral(over the particle pitch angle)in the superbanana plateau NTV regime in ITER.These findings are qualitatively insensitive to variations of a range of factors including the wall resistivity,the plasma pedestal flow and the assumed frequency of the rotating RMP field.展开更多
The monument thermal effect(MTE)displacements could result in periodical signals with several mil-limeters magnitudes in the vertical and horizontal GPS position time series.However,the interaction ofvarious origins o...The monument thermal effect(MTE)displacements could result in periodical signals with several mil-limeters magnitudes in the vertical and horizontal GPS position time series.However,the interaction ofvarious origins of periodic signals in GPS observations makes it difficult to isolate the millimeter-levelMTE displacement from other signals and noises.In this study,to assess the diurnal and semidiurnalsignals induced by MTE,we processed 12 very short GPS baselines(VSGB)with length<150 m.Themonument pairs for each baseline differ in their heights,horizontal structure,or base foundations.Meanwhile,two zero-baselines were also processed as the control group.Results showed that the sea-sonal signals observed in VSGB time series in the horizontal and vertical directions,were mainly inducedby seasonal MTE.Time-varying diurnal and semidiurnal signals with amplitude up to 4 mm wereobserved in the vertical direction for baselines with monument height difference(MHD)larger than10 m.Horizontal diurnal signal with an amplitude of about 2 mm was also detected for baselines withnon-axisymmetric monument structure.The orientation of the detected horizontal displacement wascoherent with the direction of daily temperature variation(DTV)driven by direct solar radiation,whichindicates that the diurnal and semidiurnal signals are likely induced by MTE.The observed high-frequency MTE displacements,if not well modeled and removed,may propagate into spurious long-term signals and bias the velocity estimation in the daily GPS time series.展开更多
Sea topography information holds significant importance in oceanic research and the climate change detection.Radar imaging altimetry has emerged as the leading approach for global ocean observation,employing synthetic...Sea topography information holds significant importance in oceanic research and the climate change detection.Radar imaging altimetry has emerged as the leading approach for global ocean observation,employing synthetic aperture radar(SAR)interferometry to enhance the spatial resolution of Sea topography.Nevertheless,current payload capacity and satellite hardware limitations prevent the extension of the interferometric baseline by enlarging the physical antenna size.This constraint hinders achieving centimeter-level accuracy in interferometric altimetry.To address this challenge,we conducted a numerical simulation to assess the viability of a large baseline interferometric imaging altimeter(LB-IIA).By controlling the baseline within the range of 600-1000 m through spiral orbit design in two satellites and mitigating baseline de-correlation with the carrier frequency shift(CFS)technique,we aimed to overcome the above limitations.Our findings demonstrate the efficacy of the CFS technique in compensating for baseline decoherence,elevating coherence from less than 0.1 to over 0.85.Concurrently.The height difference accuracy between neighboring sea surfaces reaches 1 cm within a 1 km resolution.This study is anticipated to serve as a foundational reference for future interferometric imaging altimeter development,catering to the demand for high-precision sea topography data in accurate global bathymetry inversion.展开更多
The linear and nonlinear simulations are carried out using the gyrokinetic code NLT for the electrostatic instabilities in the core region of a deuterium plasma based on the International Thermonuclear Experimental Re...The linear and nonlinear simulations are carried out using the gyrokinetic code NLT for the electrostatic instabilities in the core region of a deuterium plasma based on the International Thermonuclear Experimental Reactor(ITER)baseline scenario.The kinetic electron effects on the linear frequency and nonlinear transport are studied by adopting the adiabatic electron model and the fully drift-kinetic electron model in the NLT code,respectively.The linear simulations focus on the dependence of linear frequency on the plasma parameters,such as the ion and electron temperature gradientsκ_(Ti,e)≡R=L_(Ti,e),the density gradientκ_(n)≡R/L_(n)and the ion-electron temperature ratioτ=T_(e)=T_(i).Here,is the major radius,and T_(e)and T_(i)denote the electron and ion temperatures,respectively.L_(A)=-(δ_(r)lnA)^(-1)is the gradient scale length,with denoting the density,the ion and electron temperatures,respectively.In the kinetic electron model,the ion temperature gradient(ITG)instability and the trapped electron mode(TEM)dominate in the small and large k_(θ)region,respectively,wherek_(θ)is the poloidal wavenumber.The TEMdominant region becomes wider by increasing(decreasing)κ_(T_(e))(κ_(T_(i)))or by decreasingκ_(n).For the nominal parameters of the ITER baseline scenario,the maximum growth rate of dominant ITG instability in the kinetic electron model is about three times larger than that in the adiabatic electron model.The normalized linear frequency depends on the value ofτ,rather than the value of T_(e)or T_(i),in both the adiabatic and kinetic electron models.The nonlinear simulation results show that the ion heat diffusivity in the kinetic electron model is quite a lot larger than that in the adiabatic electron model,the radial structure is finer and the time oscillation is more rapid.In addition,the magnitude of the fluctuated potential at the saturated stage peaks in the ITGdominated region,and contributions from the TEM(dominating in the higher k_(θ)region)to the nonlinear transport can be neglected.In the adiabatic electron model,the zonal radial electric field is found to be mainly driven by the turbulent energy flux,and the contribution of turbulent poloidal Reynolds stress is quite small due to the toroidal shielding effect.However,in the kinetic electron model,the turbulent energy flux is not strong enough to drive the zonal radial electric field in the nonlinear saturated stage.The kinetic electron effects on the mechanism of the turbulence-driven zonal radial electric field should be further investigated.展开更多
Clinical practice guidelines drive clinical practice and clinicians rely to them when trying to answer their most common questions.One of the most important position papers in the field of gastro-esophageal reflux dis...Clinical practice guidelines drive clinical practice and clinicians rely to them when trying to answer their most common questions.One of the most important position papers in the field of gastro-esophageal reflux disease(GERD)is the one produced by the Lyon Consensus.Recently an updated second version has been released.Mean nocturnal baseline impedance(MNBI)was proposed by the first Consensus to act as supportive evidence for GERD diagnosis.Originally a cut-off of 2292 Ohms was proposed,a value revised in the second edition.The updated Consensus recommended that an MNBI<1500 Ohms strongly suggests GERD while a value>2500 Ohms can be used to refute GERD.The proposed cut-offs move in the correct direction by diminishing the original cut-off,nevertheless they arise from a study of normal subjects where cut-offs were provided by measuring the mean value±2SD and not in symptomatic patients.However,data exist that even symptomatic patients with inconclusive disease or reflux hypersensitivity(RH)show lower MNBI values in comparison to normal subjects or patients with functional heartburn(FH).Moreover,according to the data,MNBI,even among symptomatic patients,is affected by age and body mass index.Also,various studies have proposed different cut-offs by using receiver operating characteristic curve analysis even lower than the one proposed.Finally,no information is given for patients submitted to on-proton pump inhibitors pH-impedance studies even if new and extremely important data now exist.Therefore,even if MNBI is an extremely important tool when trying to approach patients with reflux symptoms and could distinguish conclusive GERD from RH or FH,its values should be interpreted with caution.展开更多
The study on designs for the baseline parameterization has aroused attention in recent years. This paper focuses on two-level regular designs for the baseline parameterization. A general result on the relationship bet...The study on designs for the baseline parameterization has aroused attention in recent years. This paper focuses on two-level regular designs for the baseline parameterization. A general result on the relationship between K-aberration and word length pattern is developed.展开更多
Arctic shipping poses environmental risks due to the region’s fragile ecosystems and rapid climate changes.Effective risk assessment tools are needed to ensure sustainable expansion and to carry out environmental imp...Arctic shipping poses environmental risks due to the region’s fragile ecosystems and rapid climate changes.Effective risk assessment tools are needed to ensure sustainable expansion and to carry out environmental impact assessments.This paper explores applications of Failure Modes and Effects Analysis(FMEA)and Systems-Theoretic Process Analysis(STPA)coupled with the consequences of a“Dynamic baseline approach”for Arctic shipping environmental impact assessment.Shipping entails complex interactions between environmental,technical,human,and organizational factors.FMEA identifies failure modes and their effects through component-level analysis.STPA examines how unsafe control actions can emerge from interactions between system components.Combining these techniques with a dynamic(variable)baseline,accounting for inherent ongoing changing Arctic conditions,offers a robust methodology.A qualitative case study shows that prioritizing hazards by risk,yields highest concerns,as increased greenhouse gas emissions,black carbon deposition on ice and snow,and response delays to accidents represent some of the most important identified threats to the environment.The use of FMEA and STPA are complementary,and differences are highlighted.The methodology applied,should be representative for the qualitative risk analysis methodology,and while the findings are impacted by the perspectives of the authors,the process followed is intended to identify and rank risks in a consistent manner.Mitigations measures must be in place to target these issues.Constant monitoring of the changing ecological and socioeconomic Arctic baselines supports the responses.This methodology offers a starting point for systematically addressing environmental impact risks in the data-limited Arctic.Integrating failure modes and effect analysis,system theories and dynamic baselines,account for identification of the complex interactions,influencing environmental risks in this rapidly evolving region.展开更多
In the case of a medium-long baseline, for real-time kinematic (RTK) positioning, the fixed rate of integer ambiguity is low due to the distance between the base station and the observation station. Moreover, the atmo...In the case of a medium-long baseline, for real-time kinematic (RTK) positioning, the fixed rate of integer ambiguity is low due to the distance between the base station and the observation station. Moreover, the atmospheric delay after differential processing cannot be ignored. For correcting the residual atmospheric errors, we proposed a GPS/BDS/Galileo/GLONASS four-system fusion RTK positioning algorithm, which is based on the extended Kalman filter (EKF) algorithm. After realizing the spatio-temporal unification of multiple global navigation satellite systems (GNSSs), we introduced a parameter estimation of atmospheric errors based on the EKF model, using the least-squares integer ambiguity decorrelation adjustment (LAMBDA) to calculate the integer ambiguity. After conducting experiments for different baselines, the proposed RTK positioning algorithm can achieve centimeter-level positioning accuracy in the case of medium-long baselines. In addition, the time required to solve the fixed solution is shorter than that of the traditional RTK positioning algorithm.展开更多
[Objective] This study aimed to avoid and delay the generation of resis- tance in Botrytis cinerea to boscalid. [Method] The sensitivity of Botrytis cinerea to boscalid was tested by the mycelial growth rate method. T...[Objective] This study aimed to avoid and delay the generation of resis- tance in Botrytis cinerea to boscalid. [Method] The sensitivity of Botrytis cinerea to boscalid was tested by the mycelial growth rate method. The distribution of sensitivity variation of B. cinerea to boscalid in different regions was cleared, and the sen- sitivity baseline of B. cinerea from Liaoning Province to boscalid was established. [Result] The ECso values of B. cinerea strains from Liaoning Province ranged from 0.080 0 to 7.787 2μg/ml, and the highest ECho value was 97.34 times higher than the minimum. The average EC50 value （1.973μg/ml） of the 158 strains was treated as the baseline sensitivity of B. cinerea from Liaoning Province to boscalid. [Conclu- sion] It is essential to conduct a risk assessment of drug resistance in B. cinerea to boscalid.展开更多
A frequency-domain equalizer with a mixed-signal adaptive control loop and a novel baseline wander （BLW） canceller are proposed. The equalizer is independent of channel-modeling accuracy,and its control loop is intr...A frequency-domain equalizer with a mixed-signal adaptive control loop and a novel baseline wander （BLW） canceller are proposed. The equalizer is independent of channel-modeling accuracy,and its control loop is intrinsically stable. An AGC function is incorporated into the equalizer without an extra AGC circuit. The proposed BLW canceller uses a peak detector to monitor the BLW and full feedback method to accomplish BLW canceling. High canceling accuracy and robust performance are achieved. The circuits are tested in 0.25μm CMOS technology. Better performance and smaller silicon area are achieved compared with results in the literature.展开更多
When the cycle slips take place in the attitude determination of a moving platform, the precision of the attitude will be impaired badly. A method of cycle slip detection and correction is proposed, which is suitable ...When the cycle slips take place in the attitude determination of a moving platform, the precision of the attitude will be impaired badly. A method of cycle slip detection and correction is proposed, which is suitable to the dynamic measurement using GPS carrier phase： the cycle slips detection is first achieved by triple difference observables, then the cycle slips correction is performed with baseline length constraint. The simulation results show that the proposed method is effective to the dynamic cycle slips problem.展开更多
AIM: To characterize the baseline profiles of patients aged 70 years and above with hepatocellular carcinoma (HCC).METHODS: A series of 127 consecutive patients with HCC were enrolled between 2000 and 2004, and none o...AIM: To characterize the baseline profiles of patients aged 70 years and above with hepatocellular carcinoma (HCC).METHODS: A series of 127 consecutive patients with HCC were enrolled between 2000 and 2004, and none of them had been diagnosed as having HCC previously. Baseline profiles, including parameters of hepatic function such as serum transaminase and prothrombin time [PT (% activity)] were compared between patients aged ≥70 and ＜70 years.RESULTS: Patients ≥70 years old showed significantly lower levels of aspartate aminotransferase (P = 0.04)and alanine aminotransferase (P = 0.01), and significantly higher PTs (P= 0.04) and platelet counts (P = 0.02).Concomitantly, among ≥70-year-old patients, HCC was more common in non-cirrhotics, whereas among patients ＜70 years old, HCC was more common in cirrhotics. There was no significant difference between the groups in the number or size of tumors.CONCLUSION: Older HCC patients showed less inflammation and better preservation of hepatic function, indicating that not only cirrhotic patients but also noncirrhotic patients should be considered as a high-risk group among the elderly.展开更多
文摘This paper delves into the baseline design under the baseline parameterization model in experimental design, focusing on the relationship between the K-aberration criterion and the word length pattern (WLP) of regular two-level designs. The paper provides a detailed analysis of the relationship between K5and the WLP for regular two-level designs with resolution t=3, and proposes corresponding theoretical results. These results not only theoretically reveal the connection between the orthogonal parameterization model and the baseline parameterization model but also provide theoretical support for finding the K-aberration optimal regular two-level baseline designs. It demonstrates how to apply these theories to evaluate and select the optimal experimental designs. In practical applications, experimental designers can utilize the theoretical results of this paper to quickly assess and select regular two-level baseline designs with minimal K-aberration by analyzing the WLP of the experimental design. This allows for the identification of key factors that significantly affect the experimental outcomes without frequently changing the factor levels, thereby maximizing the benefits of the experiment.
基金supported by the National Key Research and Development Program of China(Grant No.2023YFF1204803)the Natural Science Foundation of Jiangsu Province,China(Grant No.BK20190736)+1 种基金the Fundamental Research Funds for the Central Universities(Grant No.NJ2024029)the National Natural Science Foundation of China(Grant Nos.81701346 and 62201265).
文摘The natural visibility graph method has been widely used in physiological signal analysis,but it fails to accurately handle signals with data points below the baseline.Such signals are common across various physiological measurements,including electroencephalograph(EEG)and functional magnetic resonance imaging(fMRI),and are crucial for insights into physiological phenomena.This study introduces a novel method,the baseline perspective visibility graph(BPVG),which can analyze time series by accurately capturing connectivity across data points both above and below the baseline.We present the BPVG construction process and validate its performance using simulated signals.Results demonstrate that BPVG accurately translates periodic,random,and fractal signals into regular,random,and scale-free networks respectively,exhibiting diverse degree distribution traits.Furthermore,we apply BPVG to classify Alzheimer’s disease(AD)patients from healthy controls using EEG data and identify non-demented adults at varying dementia risk using resting-state fMRI(rs-fMRI)data.Utilizing degree distribution entropy derived from BPVG networks,our results exceed the best accuracy benchmark(77.01%)in EEG analysis,especially at channels F4(78.46%)and O1(81.54%).Additionally,our rs-fMRI analysis achieves a statistically significant classification accuracy of 76.74%.These findings highlight the effectiveness of BPVG in distinguishing various time series types and its practical utility in EEG and rs-fMRI analysis for early AD detection and dementia risk assessment.In conclusion,BPVG’s validation across both simulated and real data confirms its capability to capture comprehensive information from time series,irrespective of baseline constraints,providing a novel method for studying neural physiological signals.
基金funded by National Natural Science Foundation of China(NSFC)(Nos.12075053,11505021 and 11975068)by National Key R&D Program of China(No.2022YFE 03060002)+1 种基金by Fundamental Research Funds for the Central Universities(No.2232024G-10)supported by the U.S.DoE Office of Science(No.DE-FG02–95ER54309)。
文摘Toroidal torques,generated by the resonant magnetic perturbation(RMP)and acting on the plasma column,are numerically systematically investigated for an ITER baseline scenario.The neoclassical toroidal viscosity(NTV),in particular the resonant portion,is found to provide the dominant contribution to the total toroidal torque under the slow plasma flow regime in ITER.While the electromagnetic torque always opposes the plasma flow,the toroidal torque associated with the Reynolds stress enhances the plasma flow independent of the flow direction.A peculiar double-peak structure for the net NTV torque is robustly computed for ITER,as the toroidal rotation frequency is scanned near the zero value.This structure is found to be ultimately due to a non-monotonic behavior of the wave-particle resonance integral(over the particle pitch angle)in the superbanana plateau NTV regime in ITER.These findings are qualitatively insensitive to variations of a range of factors including the wall resistivity,the plasma pedestal flow and the assumed frequency of the rotating RMP field.
基金funded by the Independent Innovation Project of Changjiang Institute of Survey,Planning,Design and Research Corporation (CX2020Z32)supported by the National Natural Science Foundation of China (Grant Numbers42204006 and 42104028)the Open Fund of Hubei Luojia Laboratory (Grant Numbers 230100020 and 230100019)
文摘The monument thermal effect(MTE)displacements could result in periodical signals with several mil-limeters magnitudes in the vertical and horizontal GPS position time series.However,the interaction ofvarious origins of periodic signals in GPS observations makes it difficult to isolate the millimeter-levelMTE displacement from other signals and noises.In this study,to assess the diurnal and semidiurnalsignals induced by MTE,we processed 12 very short GPS baselines(VSGB)with length<150 m.Themonument pairs for each baseline differ in their heights,horizontal structure,or base foundations.Meanwhile,two zero-baselines were also processed as the control group.Results showed that the sea-sonal signals observed in VSGB time series in the horizontal and vertical directions,were mainly inducedby seasonal MTE.Time-varying diurnal and semidiurnal signals with amplitude up to 4 mm wereobserved in the vertical direction for baselines with monument height difference(MHD)larger than10 m.Horizontal diurnal signal with an amplitude of about 2 mm was also detected for baselines withnon-axisymmetric monument structure.The orientation of the detected horizontal displacement wascoherent with the direction of daily temperature variation(DTV)driven by direct solar radiation,whichindicates that the diurnal and semidiurnal signals are likely induced by MTE.The observed high-frequency MTE displacements,if not well modeled and removed,may propagate into spurious long-term signals and bias the velocity estimation in the daily GPS time series.
文摘Sea topography information holds significant importance in oceanic research and the climate change detection.Radar imaging altimetry has emerged as the leading approach for global ocean observation,employing synthetic aperture radar(SAR)interferometry to enhance the spatial resolution of Sea topography.Nevertheless,current payload capacity and satellite hardware limitations prevent the extension of the interferometric baseline by enlarging the physical antenna size.This constraint hinders achieving centimeter-level accuracy in interferometric altimetry.To address this challenge,we conducted a numerical simulation to assess the viability of a large baseline interferometric imaging altimeter(LB-IIA).By controlling the baseline within the range of 600-1000 m through spiral orbit design in two satellites and mitigating baseline de-correlation with the carrier frequency shift(CFS)technique,we aimed to overcome the above limitations.Our findings demonstrate the efficacy of the CFS technique in compensating for baseline decoherence,elevating coherence from less than 0.1 to over 0.85.Concurrently.The height difference accuracy between neighboring sea surfaces reaches 1 cm within a 1 km resolution.This study is anticipated to serve as a foundational reference for future interferometric imaging altimeter development,catering to the demand for high-precision sea topography data in accurate global bathymetry inversion.
基金supported by the National MCF Energy R&D Program of China(No.2019YFE03060000)National Natural Science Foundation of China(Nos.12005063,12375215 and 12175034)the Collaborative Innovation Program of Hefei Science Center,CAS(No.2022HSC-CIP008).
文摘The linear and nonlinear simulations are carried out using the gyrokinetic code NLT for the electrostatic instabilities in the core region of a deuterium plasma based on the International Thermonuclear Experimental Reactor(ITER)baseline scenario.The kinetic electron effects on the linear frequency and nonlinear transport are studied by adopting the adiabatic electron model and the fully drift-kinetic electron model in the NLT code,respectively.The linear simulations focus on the dependence of linear frequency on the plasma parameters,such as the ion and electron temperature gradientsκ_(Ti,e)≡R=L_(Ti,e),the density gradientκ_(n)≡R/L_(n)and the ion-electron temperature ratioτ=T_(e)=T_(i).Here,is the major radius,and T_(e)and T_(i)denote the electron and ion temperatures,respectively.L_(A)=-(δ_(r)lnA)^(-1)is the gradient scale length,with denoting the density,the ion and electron temperatures,respectively.In the kinetic electron model,the ion temperature gradient(ITG)instability and the trapped electron mode(TEM)dominate in the small and large k_(θ)region,respectively,wherek_(θ)is the poloidal wavenumber.The TEMdominant region becomes wider by increasing(decreasing)κ_(T_(e))(κ_(T_(i)))or by decreasingκ_(n).For the nominal parameters of the ITER baseline scenario,the maximum growth rate of dominant ITG instability in the kinetic electron model is about three times larger than that in the adiabatic electron model.The normalized linear frequency depends on the value ofτ,rather than the value of T_(e)or T_(i),in both the adiabatic and kinetic electron models.The nonlinear simulation results show that the ion heat diffusivity in the kinetic electron model is quite a lot larger than that in the adiabatic electron model,the radial structure is finer and the time oscillation is more rapid.In addition,the magnitude of the fluctuated potential at the saturated stage peaks in the ITGdominated region,and contributions from the TEM(dominating in the higher k_(θ)region)to the nonlinear transport can be neglected.In the adiabatic electron model,the zonal radial electric field is found to be mainly driven by the turbulent energy flux,and the contribution of turbulent poloidal Reynolds stress is quite small due to the toroidal shielding effect.However,in the kinetic electron model,the turbulent energy flux is not strong enough to drive the zonal radial electric field in the nonlinear saturated stage.The kinetic electron effects on the mechanism of the turbulence-driven zonal radial electric field should be further investigated.
文摘Clinical practice guidelines drive clinical practice and clinicians rely to them when trying to answer their most common questions.One of the most important position papers in the field of gastro-esophageal reflux disease(GERD)is the one produced by the Lyon Consensus.Recently an updated second version has been released.Mean nocturnal baseline impedance(MNBI)was proposed by the first Consensus to act as supportive evidence for GERD diagnosis.Originally a cut-off of 2292 Ohms was proposed,a value revised in the second edition.The updated Consensus recommended that an MNBI<1500 Ohms strongly suggests GERD while a value>2500 Ohms can be used to refute GERD.The proposed cut-offs move in the correct direction by diminishing the original cut-off,nevertheless they arise from a study of normal subjects where cut-offs were provided by measuring the mean value±2SD and not in symptomatic patients.However,data exist that even symptomatic patients with inconclusive disease or reflux hypersensitivity(RH)show lower MNBI values in comparison to normal subjects or patients with functional heartburn(FH).Moreover,according to the data,MNBI,even among symptomatic patients,is affected by age and body mass index.Also,various studies have proposed different cut-offs by using receiver operating characteristic curve analysis even lower than the one proposed.Finally,no information is given for patients submitted to on-proton pump inhibitors pH-impedance studies even if new and extremely important data now exist.Therefore,even if MNBI is an extremely important tool when trying to approach patients with reflux symptoms and could distinguish conclusive GERD from RH or FH,its values should be interpreted with caution.
文摘The study on designs for the baseline parameterization has aroused attention in recent years. This paper focuses on two-level regular designs for the baseline parameterization. A general result on the relationship between K-aberration and word length pattern is developed.
基金supported in parts by funds provided by“The Program for Maritim Competence(MARKOM II),”(https://www.markomii.no/om-markomii/),project 10039funds made available to UIT,The Arctic University of Norway。
文摘Arctic shipping poses environmental risks due to the region’s fragile ecosystems and rapid climate changes.Effective risk assessment tools are needed to ensure sustainable expansion and to carry out environmental impact assessments.This paper explores applications of Failure Modes and Effects Analysis(FMEA)and Systems-Theoretic Process Analysis(STPA)coupled with the consequences of a“Dynamic baseline approach”for Arctic shipping environmental impact assessment.Shipping entails complex interactions between environmental,technical,human,and organizational factors.FMEA identifies failure modes and their effects through component-level analysis.STPA examines how unsafe control actions can emerge from interactions between system components.Combining these techniques with a dynamic(variable)baseline,accounting for inherent ongoing changing Arctic conditions,offers a robust methodology.A qualitative case study shows that prioritizing hazards by risk,yields highest concerns,as increased greenhouse gas emissions,black carbon deposition on ice and snow,and response delays to accidents represent some of the most important identified threats to the environment.The use of FMEA and STPA are complementary,and differences are highlighted.The methodology applied,should be representative for the qualitative risk analysis methodology,and while the findings are impacted by the perspectives of the authors,the process followed is intended to identify and rank risks in a consistent manner.Mitigations measures must be in place to target these issues.Constant monitoring of the changing ecological and socioeconomic Arctic baselines supports the responses.This methodology offers a starting point for systematically addressing environmental impact risks in the data-limited Arctic.Integrating failure modes and effect analysis,system theories and dynamic baselines,account for identification of the complex interactions,influencing environmental risks in this rapidly evolving region.
文摘In the case of a medium-long baseline, for real-time kinematic (RTK) positioning, the fixed rate of integer ambiguity is low due to the distance between the base station and the observation station. Moreover, the atmospheric delay after differential processing cannot be ignored. For correcting the residual atmospheric errors, we proposed a GPS/BDS/Galileo/GLONASS four-system fusion RTK positioning algorithm, which is based on the extended Kalman filter (EKF) algorithm. After realizing the spatio-temporal unification of multiple global navigation satellite systems (GNSSs), we introduced a parameter estimation of atmospheric errors based on the EKF model, using the least-squares integer ambiguity decorrelation adjustment (LAMBDA) to calculate the integer ambiguity. After conducting experiments for different baselines, the proposed RTK positioning algorithm can achieve centimeter-level positioning accuracy in the case of medium-long baselines. In addition, the time required to solve the fixed solution is shorter than that of the traditional RTK positioning algorithm.
基金Supported by Special Fund for Agro-scientific Research in the Public Interest of China(201303025)~~
文摘[Objective] This study aimed to avoid and delay the generation of resis- tance in Botrytis cinerea to boscalid. [Method] The sensitivity of Botrytis cinerea to boscalid was tested by the mycelial growth rate method. The distribution of sensitivity variation of B. cinerea to boscalid in different regions was cleared, and the sen- sitivity baseline of B. cinerea from Liaoning Province to boscalid was established. [Result] The ECso values of B. cinerea strains from Liaoning Province ranged from 0.080 0 to 7.787 2μg/ml, and the highest ECho value was 97.34 times higher than the minimum. The average EC50 value （1.973μg/ml） of the 158 strains was treated as the baseline sensitivity of B. cinerea from Liaoning Province to boscalid. [Conclu- sion] It is essential to conduct a risk assessment of drug resistance in B. cinerea to boscalid.
文摘A frequency-domain equalizer with a mixed-signal adaptive control loop and a novel baseline wander （BLW） canceller are proposed. The equalizer is independent of channel-modeling accuracy,and its control loop is intrinsically stable. An AGC function is incorporated into the equalizer without an extra AGC circuit. The proposed BLW canceller uses a peak detector to monitor the BLW and full feedback method to accomplish BLW canceling. High canceling accuracy and robust performance are achieved. The circuits are tested in 0.25μm CMOS technology. Better performance and smaller silicon area are achieved compared with results in the literature.
文摘When the cycle slips take place in the attitude determination of a moving platform, the precision of the attitude will be impaired badly. A method of cycle slip detection and correction is proposed, which is suitable to the dynamic measurement using GPS carrier phase： the cycle slips detection is first achieved by triple difference observables, then the cycle slips correction is performed with baseline length constraint. The simulation results show that the proposed method is effective to the dynamic cycle slips problem.
文摘AIM: To characterize the baseline profiles of patients aged 70 years and above with hepatocellular carcinoma (HCC).METHODS: A series of 127 consecutive patients with HCC were enrolled between 2000 and 2004, and none of them had been diagnosed as having HCC previously. Baseline profiles, including parameters of hepatic function such as serum transaminase and prothrombin time [PT (% activity)] were compared between patients aged ≥70 and ＜70 years.RESULTS: Patients ≥70 years old showed significantly lower levels of aspartate aminotransferase (P = 0.04)and alanine aminotransferase (P = 0.01), and significantly higher PTs (P= 0.04) and platelet counts (P = 0.02).Concomitantly, among ≥70-year-old patients, HCC was more common in non-cirrhotics, whereas among patients ＜70 years old, HCC was more common in cirrhotics. There was no significant difference between the groups in the number or size of tumors.CONCLUSION: Older HCC patients showed less inflammation and better preservation of hepatic function, indicating that not only cirrhotic patients but also noncirrhotic patients should be considered as a high-risk group among the elderly.
