Two series of aromatic-aliphatic random copolyesters(PEBTOXS)with diverse diol ratios have been synthesized by direct melting polycondensation.Two kinds of diols(glycol(EG)and 1,4-butanediol(BD))are used in combinatio...Two series of aromatic-aliphatic random copolyesters(PEBTOXS)with diverse diol ratios have been synthesized by direct melting polycondensation.Two kinds of diols(glycol(EG)and 1,4-butanediol(BD))are used in combination in order to adjust crystallization and tensile properties,and three kinds of diacids(dimethyl terephthalate(DMT),diethyl oxalate(DEOX),and sebacic acid(SA))are involved.~1H-NMR spectra quantify both composition and structure,and show that the final contents in copolyesters appropriate to the ...展开更多
This study aims to examine the explicit solution for calculating the Average Run Length(ARL)on the triple exponentially weighted moving average(TEWMA)control chart applied to autoregressive model(AR(p)),where AR(p)is ...This study aims to examine the explicit solution for calculating the Average Run Length(ARL)on the triple exponentially weighted moving average(TEWMA)control chart applied to autoregressive model(AR(p)),where AR(p)is an autoregressive model of order p,representing a time series with dependencies on its p previous values.Additionally,the study evaluates the accuracy of both explicit and numerical integral equation(NIE)solutions for AR(p)using the TEWMA control chart,focusing on the absolute percentage relative error.The results indicate that the explicit and approximate solutions are in close agreement.Furthermore,the study investigates the performance of exponentially weighted moving average(EWMA)and TEWMA control charts in detecting changes in the process,using the relative mean index(RMI)as a measure.The findings demonstrate that the TEWMA control chart outperforms the EWMA control chart in detecting process changes,especially when the value ofλis sufficiently large.In addition,an analysis using historical data from the SET index between January 2024 and May 2024 and historical data of global annual plastic production,the results of both data sets also emphasize the superior performance of the TEWMA control chart.展开更多
As an essential function of encrypted Internet traffic analysis,encrypted traffic service classification can support both coarse-grained network service traffic management and security supervision.However,the traditio...As an essential function of encrypted Internet traffic analysis,encrypted traffic service classification can support both coarse-grained network service traffic management and security supervision.However,the traditional plaintext-based Deep Packet Inspection(DPI)method cannot be applied to such a classification.Moreover,machine learning-based existing methods encounter two problems during feature selection:complex feature overcost processing and Transport Layer Security(TLS)version discrepancy.In this paper,we consider differences between encryption network protocol stacks and propose a composite deep learning-based method in multiprotocol environments using a sliding multiple Protocol Data Unit(multiPDU)length sequence as features by fully utilizing the Markov property in a multiPDU length sequence and maintaining suitability with a TLS-1.3 environment.Control experiments show that both Length-Sensitive(LS)composite deep learning model using a capsule neural network and LS-long short time memory achieve satisfactory effectiveness in F1-score and performance.Owing to faster feature extraction,our method is suitable for actual network environments and superior to state-of-the-art methods.展开更多
AIM:To evaluate the changing trends and outcomes of colorectal cancer(CRC)surgery performed at a large single institution in Taiwan.METHODS:This study retrospectively analyzed 778patients who received colorectal cance...AIM:To evaluate the changing trends and outcomes of colorectal cancer(CRC)surgery performed at a large single institution in Taiwan.METHODS:This study retrospectively analyzed 778patients who received colorectal cancer surgery at E-Da Hospital in Taiwan from 2004 to 2009.These patients were from health examination,inpatient or emergency settings.The following attributes were analyzed in patients who had undergone CRC surgical procedures:gender,age,source,surgical type,tumor number,tumor size,number of lymph node metastasis,pathologic differentiation,chemotherapy,distant metastases,tumor site,tumor stage,average hospitalization cost and average lengths of stay(ALOS).The odds ratio and95%confidence intervals were calculated to assess the relative rate of change.Regression models were employed to predict average hospitalization cost and ALOS.RESULTS:The study sample included 458(58.87%)males and 320(41.13%)females with a mean age of64.53 years(standard deviation,12.33 years;range,28-86 years).The principal patient source came from inpatient and emergency room(96.02%).The principal tumor sites were noted at the sigmoid colon(35.73%)and rectum(30.46%).Most patients exhibited a tumor stage of 2(37.28%)or 3(34.19%).The number of new CRC surgeries performed per 100000 persons was12.21 in 2004 and gradually increased to 17.89 in 2009,representing a change of 46.52%.During the same period,the average hospitalization cost and ALOS decreased from$5303 to$4062 and from 19.7 to 14.4 d,respectively.The following factors were associated with considerably decreased hospital resource utilization:age,source,surgical type,tumor size,tumor site,and tumor stage.CONCLUSION:These results can be generalized to patient populations elsewhere in Taiwan and to other countries with similar patient profiles.展开更多
Dear Editor,Infectious bursal disease (IBD) is one of the most important diseases of the poultry. The IBD virus (IBDV), a nonenveloped virus belonging to the Birnaviridae family with a genome consisting of two segment...Dear Editor,Infectious bursal disease (IBD) is one of the most important diseases of the poultry. The IBD virus (IBDV), a nonenveloped virus belonging to the Birnaviridae family with a genome consisting of two segments of double-stranded RNA (segments A and B), targets B lymphocytes of bursa of Fabricious leading to immunosuppression. In Pakistan,poultry farming is the second biggest industry and IBD is the second biggest disease threating the poultry sector.However.展开更多
The purpose of this study was to investigate mitochondrial DNA (mtDNA) hypervariable segment-I (HVS-I) C-stretch variations and explore the significance of these variations in forensic and population genetics studies....The purpose of this study was to investigate mitochondrial DNA (mtDNA) hypervariable segment-I (HVS-I) C-stretch variations and explore the significance of these variations in forensic and population genetics studies. The C-stretch sequence variation was studied in 919 unrelated individuals from 8 Chinese ethnic groups using both direct and clone sequencing ap-proaches. Thirty eight C-stretch haplotypes were identified, and some novel and population specific haplotypes were also detected. The C-stretch genetic diversity (GD) values were relatively high, and probability (P) values were low. Additionally, C-stretch length heteroplasmy was observed in approximately 9% of individuals studied. There was a significant correlation (r=-0.961, P<0.01) between the expansion of the cytosine sequence length in the C-stretch of HVS-I and a reduction in the number of up-stream adenines. These results indicate that the C-stretch could be a useful genetic maker in forensic identification of Chinese populations. The results from the Fst and dA genetic distance matrix, neighbor-joining tree, and principal component map also suggest that C-stretch could be used as a reliable genetic marker in population genetics.展开更多
A modified exponentially weighted moving average (EWMA) scheme is one of the quality control charts suchthat this control chart can quickly detect a small shift. The average run length (ARL) is frequently used for the...A modified exponentially weighted moving average (EWMA) scheme is one of the quality control charts suchthat this control chart can quickly detect a small shift. The average run length (ARL) is frequently used for theperformance evaluation on control charts. This paper proposes the explicit formula for evaluating the average runlength on a two-sided modified exponentially weighted moving average chart under the observations of a first-orderautoregressive process, referred to as AR(1) process, with an exponential white noise. The performance comparisonof the explicit formula and the numerical integral technique is carried out using the absolute relative change forchecking the correct formula and the CPU time for testing speed of calculation. The results show that the ARL ofthe explicit formula and the numerical integral equation method are hardly different, but this explicit formula ismuch faster for calculating the ARL and offered accurate values. Furthermore, the cumulative sum, the classicalEWMA and the modified EWMA control charts are compared and the results show that the latter is better for smalland intermediate shift sizes. In addition, the explicit formula is successfully applied to real-world data in the healthfield as COVID-19 data in Thailand and Singapore.展开更多
Objective: To measure the hospital operation efficiency, study the correlation between average length of stay and hospital operation efficiency, analyze the importance of shortening average length of stay to the impro...Objective: To measure the hospital operation efficiency, study the correlation between average length of stay and hospital operation efficiency, analyze the importance of shortening average length of stay to the improvement of the hospital operation efficiency and put forward relevant policy suggestion. Methods: Based on China provincial panel data from 2003 to 2012, the hospital operation efficiencies are calculated using Super Efficiency Data Envelopment Analysis model, and the correlation between average length of stay and hospital operation efficiency is tested using Spearman rank correlation coefficient test. Results: From 2003 to 2012, the average of national hospital operation efficiency was increasing slowly and the hospital operations were inefficient in most of the areas. The national hospital operation efficiency is negatively correlated to the average length of stay. Conclusion: Measures should be taken to set average length of stay in a scientific and reasonable way, improve social and economic benefits based on the improvement of efficiency.展开更多
Porcine skeletal muscle genes play a major role in determining muscle growth and meat quality. Construction of a full-length cDNA library is an effective way to understand the expression of functional genes in muscle ...Porcine skeletal muscle genes play a major role in determining muscle growth and meat quality. Construction of a full-length cDNA library is an effective way to understand the expression of functional genes in muscle tissues. In addition, novel genes for further research could be identified in the library. In this study, we constructed a full-length cDNA library from porcine muscle tissue. The estimated average size of the cDNA inserts was 1 076 bp, and the cDNA fullness ratio was 86.2%. A total of 1 058 unique sequences with 342 contigs （32.3%） and 716 singleton （67.7%） expressed sequence tags （EST） were obtained by clustering and assembling. Meanwhile, 826 （78.1%） ESTs were categorized as known genes, and 232 （21.9%） ESTs were categorized as unknown genes. 65 novel porcine genes that exhibit no identity in the TIGR gene index of Sus scrofa and 124 full-length sequences with unknown functions were deposited in the dbEST division of GenBank （accession numbers： EU650784-EU650788, GE843306, GH228978-GH229100）. The abundantly expressed genes in porcine muscle tissue were related to muscle fiber development, energy metabolism and protein synthesis. Gene ontology analysis showed that sequences expressed in porcine muscle tissue contained a high percentage of binding activity, catalytic activity, structural molecule activity and motor activity, which involved mainly in metabolic, cellular and developmental process, distributed mainly in intracellular region. The sequence data generated in this study would provide valuable information for identifying porcine genes expressed in muscle tissue and help to advance the study on the structure and function of genes in pigs.展开更多
In the study of motif discovery, especially the transcription factor DNA binding sites discovery, a too long input sequence would return non-informative motifs rather than those biological functional motifs. This pape...In the study of motif discovery, especially the transcription factor DNA binding sites discovery, a too long input sequence would return non-informative motifs rather than those biological functional motifs. This paper gave theoretical analyses and computational experiments to suggest the length limits of the input sequence. When the sequence length exceeds a certain critical point, the probability of discovering the motif decreases sharply. The work not only gave an explanation on the unsatisfying results of the existed motif discovery problems that the input sequence length might be too long and exceed the point, but also provided an estimation of input sequence length we should accept to get more meaningful and reliable results in motif discovery.展开更多
It is given in Weil and Rosenlicht ([1], p. 15) that (resp. 2) for all non-negative integers m and n with m≠n if c is any even (resp. odd) integer. In the present paper we generalize this. Our purpose is to give othe...It is given in Weil and Rosenlicht ([1], p. 15) that (resp. 2) for all non-negative integers m and n with m≠n if c is any even (resp. odd) integer. In the present paper we generalize this. Our purpose is to give other integral sequences such that G.C.D.(ym,yn)=1 for all positive integers m and n with m≠n. Roughly speaking we show the following 1) and 2). 1) There are infinitely many polynomial sequences such that G.C.D.(fm(a),fn(a))=1 for all positive integers m and n with with m≠n and infinitely many rational?integers a. 2) There are polynomial sequences such that G.C.D.(gm(a,b),gn(a,b))=1 for all positive integers m and n with m≠n and arbitrary (rational or odd) integers a and b with G.C.D.(a,b)=1. Main results of the present paper are Theorems 1 and 2, and Corollaries 3, 4 and 5.展开更多
In this paper,based on the adjacency matrix of the network and its powers,the formulas are derived for theshortest path and the average path length,and an effective algorithm is presented.Furthermore,an example is pro...In this paper,based on the adjacency matrix of the network and its powers,the formulas are derived for theshortest path and the average path length,and an effective algorithm is presented.Furthermore,an example is providedto demonstrate the proposed method.展开更多
An unequal time interval sequence or a sequence with blanks is usually completed with average generation in grey system theory. This paper discovers that there exists obvious errors when using average generation to ge...An unequal time interval sequence or a sequence with blanks is usually completed with average generation in grey system theory. This paper discovers that there exists obvious errors when using average generation to generate internal points of non-consecutive neighbours. The average generation and the preference generation of the sequence are discussed, the concave and convex properties show the status of local sequence and propose a new idea for using the status to build up the criteria of choosing generation coefficient. Compared with the general average method of the one-dimensional data sequence, the two-dimensional data sequence is defined and its average generation is discussed, and the coefficient decision method for the preference generation is presented.展开更多
According to the issues that the predict errors of chaotic sequences rapidly accumulated in multi-step forecasting which affects the predict accuracy, we proposed a new predict algorithm based on local modeling with v...According to the issues that the predict errors of chaotic sequences rapidly accumulated in multi-step forecasting which affects the predict accuracy, we proposed a new predict algorithm based on local modeling with variable frame length and interpolation points. The core idea is that, using interpolation method to increase the available sample data, then modeling the chaos dynamics system with least square algorithm which based on the Bernstein polynomial to realize the forecasting. We use the local modeling method, looking for the optimum frame length and interpolation points in every frame to improve the predict peformance. The experimental results show that the proposed algorithm can improve the predictive ability effectively, decreasing the accumulation of iterative errors in multi-step prediction.展开更多
A virus strain, showing cytopathic effect in BHK-21 cell, was isolated from swine brains in Shaanxi Province, China, in 2007. The isolate was confirmed as Japanese encephalitis virus （JEV） by immunofluorescence ass...A virus strain, showing cytopathic effect in BHK-21 cell, was isolated from swine brains in Shaanxi Province, China, in 2007. The isolate was confirmed as Japanese encephalitis virus （JEV） by immunofluorescence assay （IFA） and reverse transcription polymerase chain reaction （RT-PCR）, and named SXBJ07. The complete nueleotide and deduced amino acid sequences of the JEV strain SXBJ07 were determined. Its single open reading frame has a total of 3 432 amino acid residues. An extensive E gene based phylogenetic analysis was performed, the result showed that SXBJ07 strain belongs to genotype I. Comparison of the SXBJ07 genomic sequence with those of the 24 fully sequenced JEV strains in published databases showed nucleotide homology ranging from 99.0 to 83.7%; amino acid homology ranged from 99.8 to 94.8%. Compared SXBJ07 with SA14-14-2 strain, the current live vaccine strain in China, the homology of amino acid in envelope gene was 97.0%; and there were amino acid substitutions in 13 sites of the active domains of E protein （E1-E411）.展开更多
In order to reveal the complex network characteristics and evolution principle of China aviation network,the relationship between the average degree and the average path length of edge vertices of China aviation netwo...In order to reveal the complex network characteristics and evolution principle of China aviation network,the relationship between the average degree and the average path length of edge vertices of China aviation network in 1988,1994,2001,2008 and 2015 was studied.According to the theory and method of complex network,the network system was constructed with the city where the airport was located as the network node and the airline as the edge of the network.On the basis of the statistical data,the average degree and average path length of edge vertices of China aviation network in 1988,1994,2001,2008 and 2015 were calculated.Through regression analysis,it was found that the average degree had a logarithmic relationship with the average path length of edge vertices and the two parameters of the logarithmic relationship had linear evolutionary trace.展开更多
In order to reveal the complex network feature and its evolution principle of aviation network of China,probability distribution and its evolution trace of average length of node path of aviation network of China were...In order to reveal the complex network feature and its evolution principle of aviation network of China,probability distribution and its evolution trace of average length of node path of aviation network of China were researched according to statistics data in years 1988,1994,2001,2008 and 2015 of civil aviation of China.Floyd algorithm to calculate the path length between any two nodes of network was applied and average length of node path of aviation network was obtained according to this algorithm.It was discovered that average length of node path to other nodes had normal distribution function in each year.At meantime,the location parameter and scale parameter of normal distribution function had linear evolution trace.Airline rate was an index to describe the density of airline.It was found that average length of node path of aviation network of China evolved synchronously with airline rate and they had linear relationship.展开更多
In order to reveal the complex network characteristics and evolution principle of China aviation network,the relationship between the node degree and the average path length of China aviation network in 1988,1994,2001...In order to reveal the complex network characteristics and evolution principle of China aviation network,the relationship between the node degree and the average path length of China aviation network in 1988,1994,2001,2008 and 2015 was studied.According to the theory and method of complex network,the network system was constructed with the city where the airport was located as the network node and the airline as the edge of the network.On the basis of the statistical data,the node average path length of China aviation network in 1988,1994,2001,2008 and 2015 was calculated.Through regression analysis,it was found that the node degree had a logarithmic relationship with the average length of node path,and the two parameters of the logarithmic relationship had linear evolutionary trace.Key word:China aviation network,complex network,node degree,average length of node path,logarithmic relationship,evolutionary trace.展开更多
The fiber length trait （FLT） of 538 individuals from nature birch population in Maorshan region, Heilongjang, China were measured, of which 100 individuals were selected as representative variety of correlated fragm...The fiber length trait （FLT） of 538 individuals from nature birch population in Maorshan region, Heilongjang, China were measured, of which 100 individuals were selected as representative variety of correlated fragments screening with random amplified polymorphism DNA （RAPD） technique. In total of 20 RAPD primers were tested through multiple regression analysis between amplified strip and the character behaviors, and a correlative segment BFLR-16 was obtained. The correlation coefficient between BFLI-16 and FLT was 0.6144, with the significant level of 1%. BFLI-16 was then cloned, sequenced and transformed into SCAR marker. The percentage of identifying long fiber birches by this SCAR was more than 92. The result indicates that the SCAR markers has high specificity for the long fiber individuals and is highly linked with the gene controlling the character of fiber length, and its existence is significantly correlative with the increase in the fiber length.展开更多
正交时频空(Orthogonal Time Frequency Space,OTFS)调制因其在高多普勒频偏环境下的可靠传输能力,已成为低轨卫星等高动态通信场景的关键技术。然而,作为多载波调制技术,OTFS信号的高峰均功率比(Peak-to-Average Power Ratio,PAPR)易...正交时频空(Orthogonal Time Frequency Space,OTFS)调制因其在高多普勒频偏环境下的可靠传输能力,已成为低轨卫星等高动态通信场景的关键技术。然而,作为多载波调制技术,OTFS信号的高峰均功率比(Peak-to-Average Power Ratio,PAPR)易导致功放进入非线性工作状态,产生信号失真,影响通信可靠性和稳定性。格雷互补序列因其特殊的定义,使得该序列的最大峰均比不超过3 dB。基于里德-穆勒(Reed-Muller,RM)编码与格雷互补序列之间的特殊联系,提出了一种基于RM编码的OTFS系统的峰均功率比抑制方法。在发射端,首先利用RM编码将原始比特流序列编码转换为格雷互补序列形式,再进行星座映射与OTFS调制,得到低峰均功率比的发射信号。在接收端,为了实现对这种特殊编码信号的准确译码,设计了一种两步级联译码算法,通过陪集选择译码与单项式系数译码的级联实现了对具有格雷互补序列的RM编码的纠错译码,保证了通信传输的可靠性。仿真结果表明,在低轨卫星通信场景下,该编码方法可以将OTFS系统发射信号的峰均功率比抑制在3 dB以内;相较于OFDM系统,OTFS系统具有更强的鲁棒性;两步级联译码算法实现了较高信噪比(>6 dB)下更高的传输可靠性。上述方案的提出不仅为OTFS调制技术在星地高动态通信场景中的应用提供了有力的技术支持,也为未来多载波调制信号的峰均比抑制提供了新的参考。展开更多
基金This work was supported by China Postdoctoral Foundation(No.2003034321)Young Teacher Foundation of Tianjin University.
文摘Two series of aromatic-aliphatic random copolyesters(PEBTOXS)with diverse diol ratios have been synthesized by direct melting polycondensation.Two kinds of diols(glycol(EG)and 1,4-butanediol(BD))are used in combination in order to adjust crystallization and tensile properties,and three kinds of diacids(dimethyl terephthalate(DMT),diethyl oxalate(DEOX),and sebacic acid(SA))are involved.~1H-NMR spectra quantify both composition and structure,and show that the final contents in copolyesters appropriate to the ...
基金the National Science,Research and Innovation Fund(NSRF)King Mongkuts University of Technology North Bangkok under contract no.KMUTNB-FF-68-B-08.
文摘This study aims to examine the explicit solution for calculating the Average Run Length(ARL)on the triple exponentially weighted moving average(TEWMA)control chart applied to autoregressive model(AR(p)),where AR(p)is an autoregressive model of order p,representing a time series with dependencies on its p previous values.Additionally,the study evaluates the accuracy of both explicit and numerical integral equation(NIE)solutions for AR(p)using the TEWMA control chart,focusing on the absolute percentage relative error.The results indicate that the explicit and approximate solutions are in close agreement.Furthermore,the study investigates the performance of exponentially weighted moving average(EWMA)and TEWMA control charts in detecting changes in the process,using the relative mean index(RMI)as a measure.The findings demonstrate that the TEWMA control chart outperforms the EWMA control chart in detecting process changes,especially when the value ofλis sufficiently large.In addition,an analysis using historical data from the SET index between January 2024 and May 2024 and historical data of global annual plastic production,the results of both data sets also emphasize the superior performance of the TEWMA control chart.
基金supported by the General Program of the National Natural Science Foundation of China under Grant No.62172093the National Key R&D Program of China under Grant No.2018YFB1800602+1 种基金2019 Industrial Internet Innovation and Development Project,Ministry of Industry and Information Technology(MIIT)under Grant No.6709010003Ministry of Education-China Mobile Research Fund under Grant No.MCM20180506。
文摘As an essential function of encrypted Internet traffic analysis,encrypted traffic service classification can support both coarse-grained network service traffic management and security supervision.However,the traditional plaintext-based Deep Packet Inspection(DPI)method cannot be applied to such a classification.Moreover,machine learning-based existing methods encounter two problems during feature selection:complex feature overcost processing and Transport Layer Security(TLS)version discrepancy.In this paper,we consider differences between encryption network protocol stacks and propose a composite deep learning-based method in multiprotocol environments using a sliding multiple Protocol Data Unit(multiPDU)length sequence as features by fully utilizing the Markov property in a multiPDU length sequence and maintaining suitability with a TLS-1.3 environment.Control experiments show that both Length-Sensitive(LS)composite deep learning model using a capsule neural network and LS-long short time memory achieve satisfactory effectiveness in F1-score and performance.Owing to faster feature extraction,our method is suitable for actual network environments and superior to state-of-the-art methods.
文摘AIM:To evaluate the changing trends and outcomes of colorectal cancer(CRC)surgery performed at a large single institution in Taiwan.METHODS:This study retrospectively analyzed 778patients who received colorectal cancer surgery at E-Da Hospital in Taiwan from 2004 to 2009.These patients were from health examination,inpatient or emergency settings.The following attributes were analyzed in patients who had undergone CRC surgical procedures:gender,age,source,surgical type,tumor number,tumor size,number of lymph node metastasis,pathologic differentiation,chemotherapy,distant metastases,tumor site,tumor stage,average hospitalization cost and average lengths of stay(ALOS).The odds ratio and95%confidence intervals were calculated to assess the relative rate of change.Regression models were employed to predict average hospitalization cost and ALOS.RESULTS:The study sample included 458(58.87%)males and 320(41.13%)females with a mean age of64.53 years(standard deviation,12.33 years;range,28-86 years).The principal patient source came from inpatient and emergency room(96.02%).The principal tumor sites were noted at the sigmoid colon(35.73%)and rectum(30.46%).Most patients exhibited a tumor stage of 2(37.28%)or 3(34.19%).The number of new CRC surgeries performed per 100000 persons was12.21 in 2004 and gradually increased to 17.89 in 2009,representing a change of 46.52%.During the same period,the average hospitalization cost and ALOS decreased from$5303 to$4062 and from 19.7 to 14.4 d,respectively.The following factors were associated with considerably decreased hospital resource utilization:age,source,surgical type,tumor size,tumor site,and tumor stage.CONCLUSION:These results can be generalized to patient populations elsewhere in Taiwan and to other countries with similar patient profiles.
基金supported by the National Key Research and Development Program of China (Nos. 2016YFE0203200, 2017YFD0500704)the Major Project of National Natural Science Foundation of China (No. 31430087)the Modern Agro-industry Technology Research System (No. CARS-41-G15)
文摘Dear Editor,Infectious bursal disease (IBD) is one of the most important diseases of the poultry. The IBD virus (IBDV), a nonenveloped virus belonging to the Birnaviridae family with a genome consisting of two segments of double-stranded RNA (segments A and B), targets B lymphocytes of bursa of Fabricious leading to immunosuppression. In Pakistan,poultry farming is the second biggest industry and IBD is the second biggest disease threating the poultry sector.However.
基金supported by the Sciences and Technological Fundamental Resources Data of the Ministry of Education, China (No. 505015)the Key Project for Science and Technology of Shaanxi Province, China (No. 2004K09-G12)
文摘The purpose of this study was to investigate mitochondrial DNA (mtDNA) hypervariable segment-I (HVS-I) C-stretch variations and explore the significance of these variations in forensic and population genetics studies. The C-stretch sequence variation was studied in 919 unrelated individuals from 8 Chinese ethnic groups using both direct and clone sequencing ap-proaches. Thirty eight C-stretch haplotypes were identified, and some novel and population specific haplotypes were also detected. The C-stretch genetic diversity (GD) values were relatively high, and probability (P) values were low. Additionally, C-stretch length heteroplasmy was observed in approximately 9% of individuals studied. There was a significant correlation (r=-0.961, P<0.01) between the expansion of the cytosine sequence length in the C-stretch of HVS-I and a reduction in the number of up-stream adenines. These results indicate that the C-stretch could be a useful genetic maker in forensic identification of Chinese populations. The results from the Fst and dA genetic distance matrix, neighbor-joining tree, and principal component map also suggest that C-stretch could be used as a reliable genetic marker in population genetics.
基金The research was supported by King Mongkut’s University of Technology North Bangkok Contract No.KMUTNB-62-KNOW-018.
文摘A modified exponentially weighted moving average (EWMA) scheme is one of the quality control charts suchthat this control chart can quickly detect a small shift. The average run length (ARL) is frequently used for theperformance evaluation on control charts. This paper proposes the explicit formula for evaluating the average runlength on a two-sided modified exponentially weighted moving average chart under the observations of a first-orderautoregressive process, referred to as AR(1) process, with an exponential white noise. The performance comparisonof the explicit formula and the numerical integral technique is carried out using the absolute relative change forchecking the correct formula and the CPU time for testing speed of calculation. The results show that the ARL ofthe explicit formula and the numerical integral equation method are hardly different, but this explicit formula ismuch faster for calculating the ARL and offered accurate values. Furthermore, the cumulative sum, the classicalEWMA and the modified EWMA control charts are compared and the results show that the latter is better for smalland intermediate shift sizes. In addition, the explicit formula is successfully applied to real-world data in the healthfield as COVID-19 data in Thailand and Singapore.
文摘Objective: To measure the hospital operation efficiency, study the correlation between average length of stay and hospital operation efficiency, analyze the importance of shortening average length of stay to the improvement of the hospital operation efficiency and put forward relevant policy suggestion. Methods: Based on China provincial panel data from 2003 to 2012, the hospital operation efficiencies are calculated using Super Efficiency Data Envelopment Analysis model, and the correlation between average length of stay and hospital operation efficiency is tested using Spearman rank correlation coefficient test. Results: From 2003 to 2012, the average of national hospital operation efficiency was increasing slowly and the hospital operations were inefficient in most of the areas. The national hospital operation efficiency is negatively correlated to the average length of stay. Conclusion: Measures should be taken to set average length of stay in a scientific and reasonable way, improve social and economic benefits based on the improvement of efficiency.
基金supported by the National Basic Research Program of China(2007CB116201)
文摘Porcine skeletal muscle genes play a major role in determining muscle growth and meat quality. Construction of a full-length cDNA library is an effective way to understand the expression of functional genes in muscle tissues. In addition, novel genes for further research could be identified in the library. In this study, we constructed a full-length cDNA library from porcine muscle tissue. The estimated average size of the cDNA inserts was 1 076 bp, and the cDNA fullness ratio was 86.2%. A total of 1 058 unique sequences with 342 contigs （32.3%） and 716 singleton （67.7%） expressed sequence tags （EST） were obtained by clustering and assembling. Meanwhile, 826 （78.1%） ESTs were categorized as known genes, and 232 （21.9%） ESTs were categorized as unknown genes. 65 novel porcine genes that exhibit no identity in the TIGR gene index of Sus scrofa and 124 full-length sequences with unknown functions were deposited in the dbEST division of GenBank （accession numbers： EU650784-EU650788, GE843306, GH228978-GH229100）. The abundantly expressed genes in porcine muscle tissue were related to muscle fiber development, energy metabolism and protein synthesis. Gene ontology analysis showed that sequences expressed in porcine muscle tissue contained a high percentage of binding activity, catalytic activity, structural molecule activity and motor activity, which involved mainly in metabolic, cellular and developmental process, distributed mainly in intracellular region. The sequence data generated in this study would provide valuable information for identifying porcine genes expressed in muscle tissue and help to advance the study on the structure and function of genes in pigs.
文摘In the study of motif discovery, especially the transcription factor DNA binding sites discovery, a too long input sequence would return non-informative motifs rather than those biological functional motifs. This paper gave theoretical analyses and computational experiments to suggest the length limits of the input sequence. When the sequence length exceeds a certain critical point, the probability of discovering the motif decreases sharply. The work not only gave an explanation on the unsatisfying results of the existed motif discovery problems that the input sequence length might be too long and exceed the point, but also provided an estimation of input sequence length we should accept to get more meaningful and reliable results in motif discovery.
文摘It is given in Weil and Rosenlicht ([1], p. 15) that (resp. 2) for all non-negative integers m and n with m≠n if c is any even (resp. odd) integer. In the present paper we generalize this. Our purpose is to give other integral sequences such that G.C.D.(ym,yn)=1 for all positive integers m and n with m≠n. Roughly speaking we show the following 1) and 2). 1) There are infinitely many polynomial sequences such that G.C.D.(fm(a),fn(a))=1 for all positive integers m and n with with m≠n and infinitely many rational?integers a. 2) There are polynomial sequences such that G.C.D.(gm(a,b),gn(a,b))=1 for all positive integers m and n with m≠n and arbitrary (rational or odd) integers a and b with G.C.D.(a,b)=1. Main results of the present paper are Theorems 1 and 2, and Corollaries 3, 4 and 5.
基金National Natural Science Foundation of China under the Key Project under Grant Nos.10635040 and 60774073the Natural Science Foundation of Jiangsu Province of China under Grant No.BK2007075
文摘In this paper,based on the adjacency matrix of the network and its powers,the formulas are derived for theshortest path and the average path length,and an effective algorithm is presented.Furthermore,an example is providedto demonstrate the proposed method.
文摘An unequal time interval sequence or a sequence with blanks is usually completed with average generation in grey system theory. This paper discovers that there exists obvious errors when using average generation to generate internal points of non-consecutive neighbours. The average generation and the preference generation of the sequence are discussed, the concave and convex properties show the status of local sequence and propose a new idea for using the status to build up the criteria of choosing generation coefficient. Compared with the general average method of the one-dimensional data sequence, the two-dimensional data sequence is defined and its average generation is discussed, and the coefficient decision method for the preference generation is presented.
文摘According to the issues that the predict errors of chaotic sequences rapidly accumulated in multi-step forecasting which affects the predict accuracy, we proposed a new predict algorithm based on local modeling with variable frame length and interpolation points. The core idea is that, using interpolation method to increase the available sample data, then modeling the chaos dynamics system with least square algorithm which based on the Bernstein polynomial to realize the forecasting. We use the local modeling method, looking for the optimum frame length and interpolation points in every frame to improve the predict peformance. The experimental results show that the proposed algorithm can improve the predictive ability effectively, decreasing the accumulation of iterative errors in multi-step prediction.
基金supported by the National Natural Science Foundation of China (30771067)
文摘A virus strain, showing cytopathic effect in BHK-21 cell, was isolated from swine brains in Shaanxi Province, China, in 2007. The isolate was confirmed as Japanese encephalitis virus （JEV） by immunofluorescence assay （IFA） and reverse transcription polymerase chain reaction （RT-PCR）, and named SXBJ07. The complete nueleotide and deduced amino acid sequences of the JEV strain SXBJ07 were determined. Its single open reading frame has a total of 3 432 amino acid residues. An extensive E gene based phylogenetic analysis was performed, the result showed that SXBJ07 strain belongs to genotype I. Comparison of the SXBJ07 genomic sequence with those of the 24 fully sequenced JEV strains in published databases showed nucleotide homology ranging from 99.0 to 83.7%; amino acid homology ranged from 99.8 to 94.8%. Compared SXBJ07 with SA14-14-2 strain, the current live vaccine strain in China, the homology of amino acid in envelope gene was 97.0%; and there were amino acid substitutions in 13 sites of the active domains of E protein （E1-E411）.
文摘In order to reveal the complex network characteristics and evolution principle of China aviation network,the relationship between the average degree and the average path length of edge vertices of China aviation network in 1988,1994,2001,2008 and 2015 was studied.According to the theory and method of complex network,the network system was constructed with the city where the airport was located as the network node and the airline as the edge of the network.On the basis of the statistical data,the average degree and average path length of edge vertices of China aviation network in 1988,1994,2001,2008 and 2015 were calculated.Through regression analysis,it was found that the average degree had a logarithmic relationship with the average path length of edge vertices and the two parameters of the logarithmic relationship had linear evolutionary trace.
文摘In order to reveal the complex network feature and its evolution principle of aviation network of China,probability distribution and its evolution trace of average length of node path of aviation network of China were researched according to statistics data in years 1988,1994,2001,2008 and 2015 of civil aviation of China.Floyd algorithm to calculate the path length between any two nodes of network was applied and average length of node path of aviation network was obtained according to this algorithm.It was discovered that average length of node path to other nodes had normal distribution function in each year.At meantime,the location parameter and scale parameter of normal distribution function had linear evolution trace.Airline rate was an index to describe the density of airline.It was found that average length of node path of aviation network of China evolved synchronously with airline rate and they had linear relationship.
文摘In order to reveal the complex network characteristics and evolution principle of China aviation network,the relationship between the node degree and the average path length of China aviation network in 1988,1994,2001,2008 and 2015 was studied.According to the theory and method of complex network,the network system was constructed with the city where the airport was located as the network node and the airline as the edge of the network.On the basis of the statistical data,the node average path length of China aviation network in 1988,1994,2001,2008 and 2015 was calculated.Through regression analysis,it was found that the node degree had a logarithmic relationship with the average length of node path,and the two parameters of the logarithmic relationship had linear evolutionary trace.Key word:China aviation network,complex network,node degree,average length of node path,logarithmic relationship,evolutionary trace.
基金supported by the National 863 Program (2002BA515B0401)National Natural Science Foundation of China (30571513)Foundation of Heilongjiang Province (GA06B301)
文摘The fiber length trait （FLT） of 538 individuals from nature birch population in Maorshan region, Heilongjang, China were measured, of which 100 individuals were selected as representative variety of correlated fragments screening with random amplified polymorphism DNA （RAPD） technique. In total of 20 RAPD primers were tested through multiple regression analysis between amplified strip and the character behaviors, and a correlative segment BFLR-16 was obtained. The correlation coefficient between BFLI-16 and FLT was 0.6144, with the significant level of 1%. BFLI-16 was then cloned, sequenced and transformed into SCAR marker. The percentage of identifying long fiber birches by this SCAR was more than 92. The result indicates that the SCAR markers has high specificity for the long fiber individuals and is highly linked with the gene controlling the character of fiber length, and its existence is significantly correlative with the increase in the fiber length.
文摘正交时频空(Orthogonal Time Frequency Space,OTFS)调制因其在高多普勒频偏环境下的可靠传输能力,已成为低轨卫星等高动态通信场景的关键技术。然而,作为多载波调制技术,OTFS信号的高峰均功率比(Peak-to-Average Power Ratio,PAPR)易导致功放进入非线性工作状态,产生信号失真,影响通信可靠性和稳定性。格雷互补序列因其特殊的定义,使得该序列的最大峰均比不超过3 dB。基于里德-穆勒(Reed-Muller,RM)编码与格雷互补序列之间的特殊联系,提出了一种基于RM编码的OTFS系统的峰均功率比抑制方法。在发射端,首先利用RM编码将原始比特流序列编码转换为格雷互补序列形式,再进行星座映射与OTFS调制,得到低峰均功率比的发射信号。在接收端,为了实现对这种特殊编码信号的准确译码,设计了一种两步级联译码算法,通过陪集选择译码与单项式系数译码的级联实现了对具有格雷互补序列的RM编码的纠错译码,保证了通信传输的可靠性。仿真结果表明,在低轨卫星通信场景下,该编码方法可以将OTFS系统发射信号的峰均功率比抑制在3 dB以内;相较于OFDM系统,OTFS系统具有更强的鲁棒性;两步级联译码算法实现了较高信噪比(>6 dB)下更高的传输可靠性。上述方案的提出不仅为OTFS调制技术在星地高动态通信场景中的应用提供了有力的技术支持,也为未来多载波调制信号的峰均比抑制提供了新的参考。
