We numerically simulated and experimentally studied the interfacialcarbon diffusion between diamond tooland workpiece materials.A diffusion modelwith respect to carbon atoms of diamond toolpenetrating into chips and m...We numerically simulated and experimentally studied the interfacialcarbon diffusion between diamond tooland workpiece materials.A diffusion modelwith respect to carbon atoms of diamond toolpenetrating into chips and machined surface was established.The numericalsimulation results of the diffusion process revealthat the distribution laws of carbon atoms concentration have a close relationship with the diffusion distance,the diffusion time,and the originalcarbon concentration of the work material.In addition,diamond face cutting tests of die steels with different carbon content are conducted at different depth of cuts and feed rates to verify the previous simulation results.The micro-morphology of the chips is detected by scanning electron microscopy.Energy dispersive X-ray analysis was proposed to investigate the change in carbon content of the chips surface.The experimentalresults of this work are of benefit to a better understanding on the diffusion wear mechanism in single crystaldiamond cutting of ferrous metals.Moreover,the experimentalresults show that the diffusion wear of diamond could be reduced markedly by applying ultrasonic vibration to the cutting toolcompared with conventionalturning.展开更多
With the shift in the definition of disease from non-alcoholic fatty liver disease(NAFLD)to metabolism-associated fatty liver disease(MAFLD),as well as the rapid evolution of pathological classification and therapeuti...With the shift in the definition of disease from non-alcoholic fatty liver disease(NAFLD)to metabolism-associated fatty liver disease(MAFLD),as well as the rapid evolution of pathological classification and therapeutic targets,traditional clinical teaching models face challenges such as outdated guideline updates,disjointed translation of scientific research,and limited skill training.This study proposes a dynamic training model integrating“guidelines,clinical practice,and scientific research.”Through stratified case-based teaching(e.g.,FibroScan simulator and metabolic sand table),dynamic guideline analysis(comparing old and new evidence),and the integration of scientific thinking(visualization of CAND1 protein mechanism),a teaching system that integrates theory and practice is constructed.Innovatively developed smart assistant tools(AI decision support system,VR liver biopsy simulator)and a multi-dimensional evaluation system(deviation analysis of diagnosis and treatment pathways,milestone assessment)are used while emphasizing metabolic medicine integration(continuous glucose monitoring and digital therapy)and ethical privacy protection(federated learning framework).This model aims to cultivate students’evidence-based decision-making skills and scientific research transformation thinking through dynamic knowledge base construction and interdisciplinary collaboration,providing sustainable teaching solutions to cope with the rapid iteration of NAFLD diagnosis and treatment.展开更多
基金Funded by the National High-Tech R&D Program(863 Program)of China(No.2012AA040405)
文摘We numerically simulated and experimentally studied the interfacialcarbon diffusion between diamond tooland workpiece materials.A diffusion modelwith respect to carbon atoms of diamond toolpenetrating into chips and machined surface was established.The numericalsimulation results of the diffusion process revealthat the distribution laws of carbon atoms concentration have a close relationship with the diffusion distance,the diffusion time,and the originalcarbon concentration of the work material.In addition,diamond face cutting tests of die steels with different carbon content are conducted at different depth of cuts and feed rates to verify the previous simulation results.The micro-morphology of the chips is detected by scanning electron microscopy.Energy dispersive X-ray analysis was proposed to investigate the change in carbon content of the chips surface.The experimentalresults of this work are of benefit to a better understanding on the diffusion wear mechanism in single crystaldiamond cutting of ferrous metals.Moreover,the experimentalresults show that the diffusion wear of diamond could be reduced markedly by applying ultrasonic vibration to the cutting toolcompared with conventionalturning.
文摘With the shift in the definition of disease from non-alcoholic fatty liver disease(NAFLD)to metabolism-associated fatty liver disease(MAFLD),as well as the rapid evolution of pathological classification and therapeutic targets,traditional clinical teaching models face challenges such as outdated guideline updates,disjointed translation of scientific research,and limited skill training.This study proposes a dynamic training model integrating“guidelines,clinical practice,and scientific research.”Through stratified case-based teaching(e.g.,FibroScan simulator and metabolic sand table),dynamic guideline analysis(comparing old and new evidence),and the integration of scientific thinking(visualization of CAND1 protein mechanism),a teaching system that integrates theory and practice is constructed.Innovatively developed smart assistant tools(AI decision support system,VR liver biopsy simulator)and a multi-dimensional evaluation system(deviation analysis of diagnosis and treatment pathways,milestone assessment)are used while emphasizing metabolic medicine integration(continuous glucose monitoring and digital therapy)and ethical privacy protection(federated learning framework).This model aims to cultivate students’evidence-based decision-making skills and scientific research transformation thinking through dynamic knowledge base construction and interdisciplinary collaboration,providing sustainable teaching solutions to cope with the rapid iteration of NAFLD diagnosis and treatment.