To solve the problems of deformation,micro-cracks,and residual tensile stress in laser cladding coatings,the technique of laser cladding with Fe-based memory alloy can be considered.However,the process of in-situ synt...To solve the problems of deformation,micro-cracks,and residual tensile stress in laser cladding coatings,the technique of laser cladding with Fe-based memory alloy can be considered.However,the process of in-situ synthesis of Fe-based memory alloy coatings is extremely complex.At present,there is no clear guidance scheme for its preparation process,which limits its promotion and application to some extent.Therefore,in this study,response surface methodology(RSM)was used to model the response surface between the target values and the cladding process parameters.The NSGA-2 algorithm was employed to optimize the process parameters.The results indicate that the composite optimization method consisting of RSM and the NSGA-2 algorithm can establish a more accurate model,with an error of less than 4.5%between the predicted and actual values.Based on this established model,the optimal scheme for process parameters corresponding to different target results can be rapidly obtained.The prepared coating exhibits a uniform structure,with no defects such as pores,cracks,and deformation.The surface roughness and microhardness of the coating are enhanced,the shaping quality of the coating is effectively improved,and the electrochemical corrosion performance of the coating in 3.5%NaCl solution is obviously better than that of the substrate,providing an important guide for engineering applications.展开更多
A switch from avian-typeα-2,3 to human-typeα-2,6 receptors is an essential element for the initiation of a pandemic from an avian influenza virus.Some H9N2 viruses exhibit a preference for binding to human-typeα-2,...A switch from avian-typeα-2,3 to human-typeα-2,6 receptors is an essential element for the initiation of a pandemic from an avian influenza virus.Some H9N2 viruses exhibit a preference for binding to human-typeα-2,6 receptors.This identifies their potential threat to public health.However,our understanding of the molecular basis for the switch of receptor preference is still limited.In this study,we employed the random forest algorithm to identify the potentially key amino acid sites within hemagglutinin(HA),which are associated with the receptor binding ability of H9N2 avian influenza virus(AIV).Subsequently,these sites were further verified by receptor binding assays.A total of 12 substitutions in the HA protein(N158D,N158S,A160 N,A160D,A160T,T163I,T163V,V190T,V190A,D193 N,D193G,and N231D)were predicted to prefer binding toα-2,6 receptors.Except for the V190T substitution,the other substitutions were demonstrated to display an affinity for preferential binding toα-2,6 receptors by receptor binding assays.Especially,the A160T substitution caused a significant upregulation of immune-response genes and an increased mortality rate in mice.Our findings provide novel insights into understanding the genetic basis of receptor preference of the H9N2 AIV.展开更多
For short-term PV power prediction,based on interval type-2 Takagi-Sugeno-Kang fuzzy logic systems(IT2 TSK FLS),combined with improved grey wolf optimizer(IGWO)algorithm,an IGWO-IT2 TSK FLS method was proposed.Compare...For short-term PV power prediction,based on interval type-2 Takagi-Sugeno-Kang fuzzy logic systems(IT2 TSK FLS),combined with improved grey wolf optimizer(IGWO)algorithm,an IGWO-IT2 TSK FLS method was proposed.Compared with the type-1 TSK fuzzy logic system method,interval type-2 fuzzy sets could simultaneously model both intra-personal uncertainty and inter-personal uncertainty based on the training of the existing error back propagation(BP)algorithm,and the IGWO algorithm was used for training the model premise and consequent parameters to further improve the predictive performance of the model.By improving the gray wolf optimization algorithm,the early convergence judgment mechanism,nonlinear cosine adjustment strategy,and Levy flight strategy were introduced to improve the convergence speed of the algorithm and avoid the problem of falling into local optimum.The interval type-2 TSK FLS method based on the IGWO algorithm was applied to the real-world photovoltaic power time series forecasting instance.Under the same conditions,it was also compared with different IT2 TSK FLS methods,such as type I TSK FLS method,BP algorithm,genetic algorithm,differential evolution,particle swarm optimization,biogeography optimization,gray wolf optimization,etc.Experimental results showed that the proposed method based on IGWO algorithm outperformed other methods in performance,showing its effectiveness and application potential.展开更多
Aimed at the problem that the traditional ART-2 neural network can not recognize a gradually changing course, an eternal term memory (ETM) vector is introduced into ART-2 to simulate the function of human brain, i.e. ...Aimed at the problem that the traditional ART-2 neural network can not recognize a gradually changing course, an eternal term memory (ETM) vector is introduced into ART-2 to simulate the function of human brain, i.e. the deep remembrance for the initial impression.. The eternal term memory vector is determined only by the initial vector that establishes category neuron node and is used to keep the remembrance for this vector for ever. Two times of vigilance algorithm are put forward, and the posterior input vector must first pass the first vigilance of this eternal term memory vector, only succeeded has it the qualification to begin the second vigilance of long term memory vector. The long term memory vector can be revised only when both of the vigilances are passed. Results of recognition examples show that the improved ART-2 overcomes the defect of traditional ART-2 and can recognize a gradually changing course effectively.展开更多
基金financial supports from the National Natural Science Foundation of China-Youth Project(51801076)the Provincial Colleges and Universities Natural Science Research Project of Jiangsu Province(18KJB430009)+1 种基金the Postdoctoral Research Support Project of Jiangsu Province(1601055C)the Senior Talents Research Startup of Jiangsu University(14JDG126)。
文摘To solve the problems of deformation,micro-cracks,and residual tensile stress in laser cladding coatings,the technique of laser cladding with Fe-based memory alloy can be considered.However,the process of in-situ synthesis of Fe-based memory alloy coatings is extremely complex.At present,there is no clear guidance scheme for its preparation process,which limits its promotion and application to some extent.Therefore,in this study,response surface methodology(RSM)was used to model the response surface between the target values and the cladding process parameters.The NSGA-2 algorithm was employed to optimize the process parameters.The results indicate that the composite optimization method consisting of RSM and the NSGA-2 algorithm can establish a more accurate model,with an error of less than 4.5%between the predicted and actual values.Based on this established model,the optimal scheme for process parameters corresponding to different target results can be rapidly obtained.The prepared coating exhibits a uniform structure,with no defects such as pores,cracks,and deformation.The surface roughness and microhardness of the coating are enhanced,the shaping quality of the coating is effectively improved,and the electrochemical corrosion performance of the coating in 3.5%NaCl solution is obviously better than that of the substrate,providing an important guide for engineering applications.
基金supported by the National Natural Science Foundation of China(32273037 and 32102636)the Guangdong Major Project of Basic and Applied Basic Research(2020B0301030007)+4 种基金Laboratory of Lingnan Modern Agriculture Project(NT2021007)the Guangdong Science and Technology Innovation Leading Talent Program(2019TX05N098)the 111 Center(D20008)the double first-class discipline promotion project(2023B10564003)the Department of Education of Guangdong Province(2019KZDXM004 and 2019KCXTD001).
文摘A switch from avian-typeα-2,3 to human-typeα-2,6 receptors is an essential element for the initiation of a pandemic from an avian influenza virus.Some H9N2 viruses exhibit a preference for binding to human-typeα-2,6 receptors.This identifies their potential threat to public health.However,our understanding of the molecular basis for the switch of receptor preference is still limited.In this study,we employed the random forest algorithm to identify the potentially key amino acid sites within hemagglutinin(HA),which are associated with the receptor binding ability of H9N2 avian influenza virus(AIV).Subsequently,these sites were further verified by receptor binding assays.A total of 12 substitutions in the HA protein(N158D,N158S,A160 N,A160D,A160T,T163I,T163V,V190T,V190A,D193 N,D193G,and N231D)were predicted to prefer binding toα-2,6 receptors.Except for the V190T substitution,the other substitutions were demonstrated to display an affinity for preferential binding toα-2,6 receptors by receptor binding assays.Especially,the A160T substitution caused a significant upregulation of immune-response genes and an increased mortality rate in mice.Our findings provide novel insights into understanding the genetic basis of receptor preference of the H9N2 AIV.
基金supported by National Natural Science Foundation of China(No.12172157)Key Project of Natural Science Foundation of Gansu Province(No.25JRRA150)Key Research and Development Planning Project of Gansu Province(No.23YFWA0007).
文摘For short-term PV power prediction,based on interval type-2 Takagi-Sugeno-Kang fuzzy logic systems(IT2 TSK FLS),combined with improved grey wolf optimizer(IGWO)algorithm,an IGWO-IT2 TSK FLS method was proposed.Compared with the type-1 TSK fuzzy logic system method,interval type-2 fuzzy sets could simultaneously model both intra-personal uncertainty and inter-personal uncertainty based on the training of the existing error back propagation(BP)algorithm,and the IGWO algorithm was used for training the model premise and consequent parameters to further improve the predictive performance of the model.By improving the gray wolf optimization algorithm,the early convergence judgment mechanism,nonlinear cosine adjustment strategy,and Levy flight strategy were introduced to improve the convergence speed of the algorithm and avoid the problem of falling into local optimum.The interval type-2 TSK FLS method based on the IGWO algorithm was applied to the real-world photovoltaic power time series forecasting instance.Under the same conditions,it was also compared with different IT2 TSK FLS methods,such as type I TSK FLS method,BP algorithm,genetic algorithm,differential evolution,particle swarm optimization,biogeography optimization,gray wolf optimization,etc.Experimental results showed that the proposed method based on IGWO algorithm outperformed other methods in performance,showing its effectiveness and application potential.
基金Sponsored by the National Natural Science Foundation of China (Grant No. 50305005)
文摘Aimed at the problem that the traditional ART-2 neural network can not recognize a gradually changing course, an eternal term memory (ETM) vector is introduced into ART-2 to simulate the function of human brain, i.e. the deep remembrance for the initial impression.. The eternal term memory vector is determined only by the initial vector that establishes category neuron node and is used to keep the remembrance for this vector for ever. Two times of vigilance algorithm are put forward, and the posterior input vector must first pass the first vigilance of this eternal term memory vector, only succeeded has it the qualification to begin the second vigilance of long term memory vector. The long term memory vector can be revised only when both of the vigilances are passed. Results of recognition examples show that the improved ART-2 overcomes the defect of traditional ART-2 and can recognize a gradually changing course effectively.
基金河北省自然科学基金(the Natural Science Foundation of Hebei Province of China under Grant No.A2006000941)河北省教育厅2006年科研计划(No.2006408)河北省科学技术研究与发展指导计划(No.072135142)。
