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3D slope stability analysis considering strength anisotropy by a microstructure tensor enhanced elasto-plastic finite element method 被引量:1
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作者 Wencheng Wei Hongxiang Tang +1 位作者 Xiaoyu Song Xiangji Ye 《Journal of Rock Mechanics and Geotechnical Engineering》 2025年第3期1664-1684,共21页
This article presents a micro-structure tensor enhanced elasto-plastic finite element(FE)method to address strength anisotropy in three-dimensional(3D)soil slope stability analysis.The gravity increase method(GIM)is e... This article presents a micro-structure tensor enhanced elasto-plastic finite element(FE)method to address strength anisotropy in three-dimensional(3D)soil slope stability analysis.The gravity increase method(GIM)is employed to analyze the stability of 3D anisotropic soil slopes.The accuracy of the proposed method is first verified against the data in the literature.We then simulate the 3D soil slope with a straight slope surface and the convex and concave slope surfaces with a 90turning corner to study the 3D effect on slope stability and the failure mechanism under anisotropy conditions.Based on our numerical results,the end effect significantly impacts the failure mechanism and safety factor.Anisotropy degree notably affects the safety factor,with higher degrees leading to deeper landslides.For concave slopes,they can be approximated by straight slopes with suitable boundary conditions to assess their stability.Furthermore,a case study of the Saint-Alban test embankment A in Quebec,Canada,is provided to demonstrate the applicability of the proposed FE model. 展开更多
关键词 Strength anisotropy Elasto-plastic finite element method(FEM) Three-dimensional(3D)soil slope Gravity increase method(GIM) Stability analysis Case study
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AHermitian C^(2) Differential Reproducing Kernel Interpolation Meshless Method for the 3D Microstructure-Dependent Static Flexural Analysis of Simply Supported and Functionally Graded Microplates
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作者 Chih-Ping Wu Ruei-Syuan Chang 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第10期917-949,共33页
This work develops a Hermitian C^(2) differential reproducing kernel interpolation meshless(DRKIM)method within the consistent couple stress theory(CCST)framework to study the three-dimensional(3D)microstructuredepend... This work develops a Hermitian C^(2) differential reproducing kernel interpolation meshless(DRKIM)method within the consistent couple stress theory(CCST)framework to study the three-dimensional(3D)microstructuredependent static flexural behavior of a functionally graded(FG)microplate subjected to mechanical loads and placed under full simple supports.In the formulation,we select the transverse stress and displacement components and their first-and second-order derivatives as primary variables.Then,we set up the differential reproducing conditions(DRCs)to obtain the shape functions of the Hermitian C^(2) differential reproducing kernel(DRK)interpolant’s derivatives without using direct differentiation.The interpolant’s shape function is combined with a primitive function that possesses Kronecker delta properties and an enrichment function that constituents DRCs.As a result,the primary variables and their first-and second-order derivatives satisfy the nodal interpolation properties.Subsequently,incorporating ourHermitianC^(2)DRKinterpolant intothe strong formof the3DCCST,we develop a DRKIM method to analyze the FG microplate’s 3D microstructure-dependent static flexural behavior.The Hermitian C^(2) DRKIM method is confirmed to be accurate and fast in its convergence rate by comparing the solutions it produces with the relevant 3D solutions available in the literature.Finally,the impact of essential factors on the transverse stresses,in-plane stresses,displacements,and couple stresses that are induced in the loaded microplate is examined.These factors include the length-to-thickness ratio,the material length-scale parameter,and the inhomogeneity index,which appear to be significant. 展开更多
关键词 Consistent/modified couple stress theory differential reproducing kernel methods microplates point collocation methods static flexural 3D microstructure-dependent analysis
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3-D fracture network dynamic simulation based on error analysis in rock mass of dam foundation 被引量:5
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作者 ZHONG Deng-hua WU Han +2 位作者 WU Bin-ping ZHANG Yi-chi YUE Pan 《Journal of Central South University》 SCIE EI CAS CSCD 2018年第4期919-935,共17页
Accurate 3-D fracture network model for rock mass in dam foundation is of vital importance for stability,grouting and seepage analysis of dam foundation.With the aim of reducing deviation between fracture network mode... Accurate 3-D fracture network model for rock mass in dam foundation is of vital importance for stability,grouting and seepage analysis of dam foundation.With the aim of reducing deviation between fracture network model and measured data,a 3-D fracture network dynamic modeling method based on error analysis was proposed.Firstly,errors of four fracture volume density estimation methods(proposed by ODA,KULATILAKE,MAULDON,and SONG)and that of four fracture size estimation methods(proposed by EINSTEIN,SONG and TONON)were respectively compared,and the optimal methods were determined.Additionally,error index representing the deviation between fracture network model and measured data was established with integrated use of fractal dimension and relative absolute error(RAE).On this basis,the downhill simplex method was used to build the dynamic modeling method,which takes the minimum of error index as objective function and dynamically adjusts the fracture density and size parameters to correct the error index.Finally,the 3-D fracture network model could be obtained which meets the requirements.The proposed method was applied for 3-D fractures simulation in Miao Wei hydropower project in China for feasibility verification and the error index reduced from 2.618 to 0.337. 展开更多
关键词 rock mass of dam foundation 3-D fracture network dynamic simulation fractal dimension error analysis relative absolute error(RAE) downhill simplex method
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A Periodicity Analysis of the Light Curve of 3C 454.3 被引量:3
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作者 Huai-Zhen Li Guang-Zhong Xie +4 位作者 Shu-Bai Zhou Hong-Tao Liu Guang-Wei Cha Li Ma Li-Sheng Mao 《Chinese Journal of Astronomy and Astrophysics》 CSCD 2006年第4期421-429,共9页
We analyzed the radio light curves of 3C 454.3 at frequencies 22 and 37 GHz taken from the database of Metsaeovi Radio Observatory, and found evidence of quasi-periodic activity. The light curves show great activity w... We analyzed the radio light curves of 3C 454.3 at frequencies 22 and 37 GHz taken from the database of Metsaeovi Radio Observatory, and found evidence of quasi-periodic activity. The light curves show great activity with very complicated non-sinusoidal variations. Two possible periods, a very weak one of 1.57 ± 0.12 yr and a very strong one of 6.15 ±0.50 yr were consistently identified by two methods, the Jurkevich method and power specmun estimation. The period of 6.15 ± 0.50 yr is consistent with results previously reported by Ciaramella et al. and Webb et al. Applying the binary black hole model to the central structure we found black hole masses of 1.53 × 10^9M⊙ and 1.86 × 10^8M⊙, and predicted that the next radio outburst is to take place in 2006 March and April. 展开更多
关键词 galaxies: individual 3C 454.3)-- galaxies: fundamental parameters-- methods:data analysis
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3D analysis of functionally graded material plates with complex shapes and various holes
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作者 曹志远 唐寿高 程国华 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2009年第1期13-18,共6页
In this paper, the basic formulae for the semi-analytical graded FEM on FGM members are derived. Since FGM parameters vary along three space coordinates, the parameters can be integrated in mechanical equations. There... In this paper, the basic formulae for the semi-analytical graded FEM on FGM members are derived. Since FGM parameters vary along three space coordinates, the parameters can be integrated in mechanical equations. Therefore with the parameters of a given FGM plate, problems of FGM plate under various conditions can be solved. The approach uses 1D discretization to obtain 3D solutions, which is proven to be an effective numerical method for the mechanical analyses of FGM structures. Examples of FGM plates with complex shapes and various holes are presented. 展开更多
关键词 functionally graded material semi-analytical method complex shape 3D analysis HOLE
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A novel box-counting method for quantitative fractal analysis of threedimensional pore characteristics in sandstone
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作者 Huiqing Liu Heping Xie +2 位作者 Fei Wu Cunbao Li Renbo Gao 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第4期479-489,共11页
Fractal theory offers a powerful tool for the precise description and quantification of the complex pore structures in reservoir rocks,crucial for understanding the storage and migration characteristics of media withi... Fractal theory offers a powerful tool for the precise description and quantification of the complex pore structures in reservoir rocks,crucial for understanding the storage and migration characteristics of media within these rocks.Faced with the challenge of calculating the three-dimensional fractal dimensions of rock porosity,this study proposes an innovative computational process that directly calculates the three-dimensional fractal dimensions from a geometric perspective.By employing a composite denoising approach that integrates Fourier transform(FT)and wavelet transform(WT),coupled with multimodal pore extraction techniques such as threshold segmentation,top-hat transformation,and membrane enhancement,we successfully crafted accurate digital rock models.The improved box-counting method was then applied to analyze the voxel data of these digital rocks,accurately calculating the fractal dimensions of the rock pore distribution.Further numerical simulations of permeability experiments were conducted to explore the physical correlations between the rock pore fractal dimensions,porosity,and absolute permeability.The results reveal that rocks with higher fractal dimensions exhibit more complex pore connectivity pathways and a wider,more uneven pore distribution,suggesting that the ideal rock samples should possess lower fractal dimensions and higher effective porosity rates to achieve optimal fluid transmission properties.The methodology and conclusions of this study provide new tools and insights for the quantitative analysis of complex pores in rocks and contribute to the exploration of the fractal transport properties of media within rocks. 展开更多
关键词 3D fractal analysis Fractal dimension Rock pore structure Box-counting method Permeability simulation Computational geosciences
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Static Analysis of Doubly-Curved Shell Structures of Smart Materials and Arbitrary Shape Subjected to General Loads Employing Higher Order Theories and Generalized Differential Quadrature Method
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作者 Francesco Tornabene Matteo Viscoti Rossana Dimitri 《Computer Modeling in Engineering & Sciences》 SCIE EI 2022年第12期719-798,共80页
The article proposes an Equivalent Single Layer(ESL)formulation for the linear static analysis of arbitrarily-shaped shell structures subjected to general surface loads and boundary conditions.A parametrization of the... The article proposes an Equivalent Single Layer(ESL)formulation for the linear static analysis of arbitrarily-shaped shell structures subjected to general surface loads and boundary conditions.A parametrization of the physical domain is provided by employing a set of curvilinear principal coordinates.The generalized blendingmethodology accounts for a distortion of the structure so that disparate geometries can be considered.Each layer of the stacking sequence has an arbitrary orientation and is modelled as a generally anisotropic continuum.In addition,re-entrant auxetic three-dimensional honeycomb cells with soft-core behaviour are considered in the model.The unknown variables are described employing a generalized displacement field and pre-determined through-the-thickness functions assessed in a unified formulation.Then,a weak assessment of the structural problem accounts for shape functions defined with an isogeometric approach starting fromthe computational grid.Ageneralizedmethodology has been proposed to define two-dimensional distributions of static surface loads.In the same way,boundary conditions with three-dimensional features are implemented along the shell edges employing linear springs.The fundamental relations are obtained from the stationary configuration of the total potential energy,and they are numerically tackled by employing the Generalized Differential Quadrature(GDQ)method,accounting for nonuniform computational grids.In the post-processing stage,an equilibrium-based recovery procedure allows the determination of the three-dimensional dispersion of the kinematic and static quantities.Some case studies have been presented,and a successful benchmark of different structural responses has been performed with respect to various refined theories. 展开更多
关键词 3D honeycomb anisotropic materials differential quadrature method general loads and constraints higher order theories linear static analysis weak formulation
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Numerical Investigation of Laser Surface Hardening of AISI 4340 Using 3D FEM Model for Thermal Analysis of Different Laser Scanning Patterns
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作者 Baha Tarchoun Abderrazak El Ouafi Ahmed Chebak 《Modeling and Numerical Simulation of Material Science》 2020年第3期31-54,共24页
<span style="font-family:Verdana;">Laser surface hardening is becoming one of the most successful heat treatment processes for improving wear and fatigue properties of steel parts. In this process, the... <span style="font-family:Verdana;">Laser surface hardening is becoming one of the most successful heat treatment processes for improving wear and fatigue properties of steel parts. In this process, the heating system parameters and the material properties have important effects on the achieved hardened surface characteristics. The control of these variables using predictive modeling strategies leads to the desired surface properties without following the fastidious trial and error method. However, when the dimensions of the surface to be treated are larger than the cross section of the laser beam, various laser scanning patterns can be used. Due to their effects on the hardened surface properties, the attributes of the selected scanning patterns become significant variables in the process. This paper presents numerical and experimental investigations of four scanning patterns for laser surface hardening of AISI 4340 steel. The investigations are based on exhaustive modelling and simulation efforts carried out using a 3D finite element thermal analysis and structured experimental study according to Taguchi method. The temperature distribution and the hardness profile attributes are used to evaluate the effects of heating parameters and patterns design parameters on the hardened surface characteristics. This is very useful for integrating the scanning patterns</span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">’</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> features in an efficient predictive modeling approach. A structured experimental design combined to improved statistical analysis tools </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">is</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> used</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> to</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> assess the 3D model performance. The experiments are performed on a 3 kW Nd:Yag laser system. The modeling results exhibit a great agreement between the predicted and measured values for the hardened surface characteristics. The model evaluation reveal</span></span></span><span><span><span>s </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">also its ability to provide not only accurate and robust predictions of the temperature distribution and the hardness profile as well an in-depth analysis of the effects of the process parameters.</span></span></span> 展开更多
关键词 Laser Surface Hardening 3D Thermal analysis Finite Element Modelling AISI 4340 Steel Laser Scanning Patterns Taguchi method ANOVA Nd:Yag Laser Source
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Ergodic sensitivity analysis of one-dimensional chaotic maps 被引量:1
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作者 Adam A.Śliwiak Nisha Chandramoorthy Qiqi Wang 《Theoretical & Applied Mechanics Letters》 CAS CSCD 2020年第6期438-447,共10页
Sensitivity analysis in chaotic dynamical systems is a challenging task from a computational point of view.In this work,we present a numerical investigation of a novel approach,known as the space-split sensitivity or ... Sensitivity analysis in chaotic dynamical systems is a challenging task from a computational point of view.In this work,we present a numerical investigation of a novel approach,known as the space-split sensitivity or S3 algorithm.The S3 algorithm is an ergodic-averaging method to differentiate statistics in ergodic,chaotic systems,rigorously based on the theory of hyperbolic dynamics.We illustrate S3 on one-dimensional chaotic maps,revealing its computational advantage over na?ve finite difference computations of the same statistical response.In addition,we provide an intuitive explanation of the key components of the S3 algorithm,including the density gradient function. 展开更多
关键词 Sensitivity analysis Chaotic systems ERGODICITY Space-split sensitivity(S3)method
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信号转导和转录活化因子3在骨肉瘤中的表达及临床意义
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作者 但丹 陈凤霞 +1 位作者 嘉颖 浦飞飞 《中国中医骨伤科杂志》 2025年第2期29-33,共5页
目的:探讨骨肉瘤中信号转导和转录活化因子3(STAT3)蛋白表达水平及临床意义。方法:用免疫组织化学法检测36例骨肉瘤标本中STAT3蛋白表达水平,分析STAT3表达水平与患者临床病理特征的相关性。采用Kaplan-Meier生存分析探讨STAT3表达水平... 目的:探讨骨肉瘤中信号转导和转录活化因子3(STAT3)蛋白表达水平及临床意义。方法:用免疫组织化学法检测36例骨肉瘤标本中STAT3蛋白表达水平,分析STAT3表达水平与患者临床病理特征的相关性。采用Kaplan-Meier生存分析探讨STAT3表达水平与骨肉瘤患者预后的相关性。结果:STAT3蛋白阳性反应主要定位于细胞质,36例骨肉瘤肿瘤组织中STAT3高表达31例(86.11%),癌旁组织中STAT3高表达13例(36.11%),差异有统计学意义(P<0.05);STAT3高表达与患者Enneking分期高、化疗反应较差、肺转移发生率高、总生存期短相关,差异有统计学意义(P<0.05)。结论:STAT3在骨肉瘤中高表达,其表达强度与患者不良预后正相关。 展开更多
关键词 骨肉瘤 信号转导和转录活化因子3 免疫组织化学法 生存分析 临床预后
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黄陵矿区煤矸石浸出Al_(2)O_(3)试验研究 被引量:1
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作者 张盼盼 杜美利 +1 位作者 李云英 王亚超 《金属矿山》 北大核心 2025年第5期260-264,共5页
黄陵矿区煤矸石中富含硅铝质矿物,从中提取Al_(2)O_(3)是实现区域煤矸石高附加值利用的有效途径之一。以黄陵矿区煤矸石为原料,根据其物相组成特点,设计了Na2CO3助剂煅烧活化—HCl浸取Al_(2)O_(3)的工艺,系统考察了物料比、煅烧温度、... 黄陵矿区煤矸石中富含硅铝质矿物,从中提取Al_(2)O_(3)是实现区域煤矸石高附加值利用的有效途径之一。以黄陵矿区煤矸石为原料,根据其物相组成特点,设计了Na2CO3助剂煅烧活化—HCl浸取Al_(2)O_(3)的工艺,系统考察了物料比、煅烧温度、酸浓度、液固比等因素对Al_(2)O_(3)浸出率的影响;通过Design-Expert和Box-Behnken进行了响应面优化研究,并建立了回归模型,通过响应面优化图直观地反映了各影响因素间的交互作用,优化了Al_(2)O_(3)浸出的工艺参数。结果表明,Al_(2)O_(3)的最佳浸出条件:物料比5∶6、煅烧温度800℃、HCl浓度8mol/L、液固比10∶1m L/g,对应的Al_(2)O_(3)浸出率为94.27%;诸因素对Al_(2)O_(3)浸出率影响由大到小的依次为:煅烧温度、液固比、物料比、酸浓度。通过Design-Expert建立了置信度高的回归模型,模型与试验误差小,能充分反应实际情况,研究对黄陵矿区煤矸石提铝工艺优化及其资源化利用具有重要参考价值。 展开更多
关键词 煤矸石 酸浸法 Al_(2)O_(3)浸出率 响应面分析
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Stability analysis of three-dimensional two-bench unsaturated soil slopes under seismic loading
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作者 SHAN Jun-tao WU Yi-min YANG Xiao-li 《Journal of Central South University》 CSCD 2024年第11期4187-4202,共16页
Due to rainfall infiltration,groundwater activity,geological processes,and natural erosion,soil often exhibits heterogeneity and unsaturation.Additionally,seismic events can compromise slope stability.Existing analyti... Due to rainfall infiltration,groundwater activity,geological processes,and natural erosion,soil often exhibits heterogeneity and unsaturation.Additionally,seismic events can compromise slope stability.Existing analytical solutions typically consider a single failure mode,leading to inaccurate slope stability assessments.This study analyzes the impact of matric suction through three nonlinear shear strength models and adopts a heterogeneous soil model where cohesion linearly increases with depth.An improved pseudo-dynamic method is used to account for seismic effects.Based on a three-dimensional(3D)trumpet-shaped rotational failure mechanism,a new framework is established to analyze the stability of 3D two-bench slopes in heterogeneous unsaturated soil under seismic effects.The internal energy dissipation rate and external power at failure are calculated,and the gravity increase method is introduced to derive an explicit expression for the safety factor(F_(s)).The results are compared with previously published results,demonstrating the effectiveness of the proposed method.Sensitivity analyses on different parameters are conducted,discussing the influence of various factors on F s.This study proposes a new formula for calculating the F_(s) of 3D two-bench slopes in heterogeneous unsaturated soil under seismic effects,providing a practical application for slope engineering. 展开更多
关键词 3D two-bench slope limit analysis modified pseudo-dynamic method HETEROGENEITY UNSATURATION
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GSK3/Nrf2调控的生物节律在机体衰老中的规律
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作者 陈伊琳 蒋晓波 +1 位作者 屈红林 刘瑞莲 《中国组织工程研究》 CAS 北大核心 2025年第6期1257-1264,共8页
背景:生物节律(昼夜节律)紊乱是一个典型的与衰老有关的问题,维持生物节律的正常运作可能是一种很有前景的抗衰老策略。核转录因子NF-E2相关因子2的表达具有生物节律;糖原合成酶激酶3系统代表了一个“调节阀”,它控制核转录因子NF-E2相... 背景:生物节律(昼夜节律)紊乱是一个典型的与衰老有关的问题,维持生物节律的正常运作可能是一种很有前景的抗衰老策略。核转录因子NF-E2相关因子2的表达具有生物节律;糖原合成酶激酶3系统代表了一个“调节阀”,它控制核转录因子NF-E2相关因子2水平的细微振荡。抗氧化基因转录水平的昼夜变化可以影响生物体对氧化应激的反应,但是糖原合成酶激酶3/NF-E2相关因子2在调节机体衰老中的具体分子机制仍令人困惑。目的:拟通过对该领域文献的回顾,寻找糖原合成酶激酶3/核转录因子NF-E2相关因子2调控的生物节律在机体衰老中的一般规律。方法:文献资料法通过对有关“糖原合成酶激酶3、核转录因子NF-E2相关因子2、生物节律以及衰老”等相关文献进行检索、查阅和筛选,为全文的分析奠定理论基础。对比分析法通过对所得到文献进行阅读分析,比较文献之间的异同点,为论点提供合理的理论支撑。通过对文献的进一步对比分析,理清相关指标间的关系,为全文的分析明确思路。结果与结论:①糖原合成酶激酶3可通过对节律基因的调节间接调控核转录因子NF-E2相关因子2的表达;②糖原合成酶激酶3和核转录因子NF-E2相关因子2是抗衰老程序的组成部分,且与生物节律相关;③并且糖原合成酶激酶3/核转录因子NF-E2相关因子2参与多种代谢途径,包括与衰老相关疾病(2型糖尿病和癌症)和神经退行性疾病相关的代谢途径。 展开更多
关键词 糖原合成酶激酶3 核转录因子NF-E2相关因子2 生物节律 衰老 神经退行性疾病
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RP-3航空煤油模型燃料的简化反应机理构建与验证
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作者 曾文 郭振宇 +3 位作者 刘靖 胡二江 常亚超 马宏宇 《航空动力学报》 北大核心 2025年第1期1-12,共12页
采用基于反应类的全局敏感性分析方法、组分敏感性分析方法构建了甲基环己烷(MCH)的燃料相关骨架反应机理,包含25种组分和44个反应;并采用解耦法构建了甲基环己烷的骨架反应机理,包含72种组分和383个反应;同时,采用遗传算法对燃料相关... 采用基于反应类的全局敏感性分析方法、组分敏感性分析方法构建了甲基环己烷(MCH)的燃料相关骨架反应机理,包含25种组分和44个反应;并采用解耦法构建了甲基环己烷的骨架反应机理,包含72种组分和383个反应;同时,采用遗传算法对燃料相关反应的反应速率常数进行了优化,优化后的骨架反应机理在甲基环己烷的着火延迟时间以及MCH、CO、CO_(2)摩尔分数的预测精度获得大幅提升。通过耦合正癸烷、正十二烷、异十六烷、甲基环己烷、甲苯的骨架反应机理与C0~C3的简化反应机理,构建了RP-3航空煤油模型燃料的简化反应机理(包含121种组分、469个反应);采用该简化反应机理计算得到的多工况条件下RP-3航空煤油的着火延迟时间与层流燃烧速度与相应试验值之间的误差均在5%以内,除个别工况外,氧化过程中主要组分摩尔分数的计算值与相应试验值吻合较好。 展开更多
关键词 解耦法 全局敏感性分析 简化反应机理 模型燃料 RP-3航空煤油
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啤酒酵母中(1→3)-β-D-葡聚糖的提取及其机理研究 被引量:31
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作者 黄刚良 刘曼西 +2 位作者 曹元成 曾莹春 张莉 《精细化工》 EI CAS CSCD 北大核心 2003年第8期458-459,465,共3页
分别采用酸法、酸碱法来提取啤酒酵母中的(1→3) β D 葡聚糖,然后对其产品进行多糖成分和紫外光谱分析。结果发现,在用c(CH3COOH)=0 5mol/L的水溶液提取啤酒酵母中的(1→3) β D 葡聚糖时,其产品中除含有葡聚糖外,还含有一定量的甘露... 分别采用酸法、酸碱法来提取啤酒酵母中的(1→3) β D 葡聚糖,然后对其产品进行多糖成分和紫外光谱分析。结果发现,在用c(CH3COOH)=0 5mol/L的水溶液提取啤酒酵母中的(1→3) β D 葡聚糖时,其产品中除含有葡聚糖外,还含有一定量的甘露聚糖和蛋白质这两种成分。但先用c(NaOH)=1 0mol/L的水溶液提取,再用w(CH3COOH)=4%的醋酸溶液处理时,产品为高纯度的(1→3) β D 葡聚糖。此结论由傅立叶红外光谱和核磁共振碳谱得到进一步的证实。接着从其水解机理上阐述了产生上述两种不同结果的原因,从而说明了酸碱法是从啤酒酵母中提取(1→3) β D 葡聚糖的理想途径。 展开更多
关键词 啤酒酵母 (1→3)-β-D-葡聚糖 酸法 酸碱法 提取 分析 机理
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基于UML模型的CTCS-3级列控系统功能安全分析方法 被引量:10
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作者 刘金涛 唐涛 +1 位作者 赵林 李宪 《铁道学报》 EI CAS CSCD 北大核心 2013年第10期59-66,共8页
本文利用UML支持的底层扩展机制对UML进行面向列控系统混成性的扩展,使用扩展后的UML对列控系统进行半形式化建模,并采用故障事件机制对系统的故障情况进行刻画。给出UML模型到PHAVer模型的转化规则以及故障监视器模型的建立方法,利用... 本文利用UML支持的底层扩展机制对UML进行面向列控系统混成性的扩展,使用扩展后的UML对列控系统进行半形式化建模,并采用故障事件机制对系统的故障情况进行刻画。给出UML模型到PHAVer模型的转化规则以及故障监视器模型的建立方法,利用可达集计算原理验证列控系统的PHAVer模型并对其进行功能安全性分析。以CTCS-3级列控系统的RBC交接为例,使用UML结合可达集计算对系统进行功能安全分析。分析结果表明:UML与可达集计算相结合的方法适用于CTCS-3级列控系统的功能安全分析。 展开更多
关键词 CTCS-3级系统 形式化方法 UML 可达集 功能安全分析
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基于控制关系模型的CTCS-3级列控系统功能安全分析方法 被引量:7
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作者 刘金涛 唐涛 +1 位作者 赵林 刘磊 《铁道学报》 EI CAS CSCD 北大核心 2015年第8期36-43,共8页
本文给出CTCS-3级列控系统中组件控制行为的形式化定义,并针对控制行为的时序关系,提出控制行为时序逻辑。以此时序逻辑为基础,给出控制关系模型的形式化定义,使用控制关系模型对列控系统中的控制行为关系进行刻画。利用深度优先搜索的... 本文给出CTCS-3级列控系统中组件控制行为的形式化定义,并针对控制行为的时序关系,提出控制行为时序逻辑。以此时序逻辑为基础,给出控制关系模型的形式化定义,使用控制关系模型对列控系统中的控制行为关系进行刻画。利用深度优先搜索的方式,对系统的控制关系模型进行分析,实现STPA(System-Theoretic Process Analysis)过程中不恰当控制行为的自动化辨识。以CTCS-3级列控系统的RBC交接场景为例,使用上述基于控制关系模型的STPA方法对列控系统的功能安全进行分析。分析过程表明利用形式化的控制关系模型扩展STPA的方法适用于CTCS-3级列控系统的功能安全分析。 展开更多
关键词 STPA CTCS-3级列控系统 形式化方法 功能安全分析
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猪圆环病毒3型PCR检测方法的建立与Cap基因序列分析 被引量:5
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作者 朱小甫 吴旭锦 +3 位作者 熊忙利 张文娟 尹宝英 邢蕾 《中国动物传染病学报》 CAS 北大核心 2022年第1期84-90,共7页
建立一种检测PCV3流行毒株感染的PCR方法,并分析Cap基因序列变异情况,为PCV3流行病学调查提供技术支持。根据GenBank中公开的PCV3全基因序列,分别设计了质粒构建引物和检测引物,通过构建阳性质粒、灵敏度试验、特异性试验、临床样品检... 建立一种检测PCV3流行毒株感染的PCR方法,并分析Cap基因序列变异情况,为PCV3流行病学调查提供技术支持。根据GenBank中公开的PCV3全基因序列,分别设计了质粒构建引物和检测引物,通过构建阳性质粒、灵敏度试验、特异性试验、临床样品检测试验以及测序分析,建立PCR检测方法。结果显示:建立的PCR方法检测的极限为50 copies/μL,以PRRSV、CSFV、PEDV、PRV、PPV、PCV-2的cDNA/DNA作为模板,用该方法扩增结果均为阴性,表明建立的方法特异性良好;应用该方法检测了285份样品,阳性39份,阳性率为13.7%。Cap基因序列分析显示,20株比对序列核苷酸同源性为87.1%~100%,SXSL1702与SXXA1812同源性为87.1%,在基因进化树中SXSL1702单独构成一个分支,提示SXSL1702株Cap基因与其他毒株有较大差异。成功建立了检测PCV3感染的PCR方法,为进一步流行病学调查和生物学特性研究奠定了基础。 展开更多
关键词 猪圆环病毒3 PCR检测方法 流行病学 Cap基因 序列分析
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基于因子分析和3西格玛法则的中国能源安全评价 被引量:8
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作者 郭伟 张宇 张彤 《西安工程大学学报》 CAS 2013年第5期648-654,共7页
从能源、环境和经济协调发展的角度构建我国能源安全评价指标体系,采用因子分析法确定指标权重,3西格玛法则划分指标状态并赋值,用加权求出的综合评价值分析1986~2011年能源安全形势.研究发现这26年能源形势在紧张与缓和间徘徊,... 从能源、环境和经济协调发展的角度构建我国能源安全评价指标体系,采用因子分析法确定指标权重,3西格玛法则划分指标状态并赋值,用加权求出的综合评价值分析1986~2011年能源安全形势.研究发现这26年能源形势在紧张与缓和间徘徊,但总体状况基本安全;能源形势2001-2011年问较1986-2000年严峻,但“十一五”时期有所好转,这些基本符合我国能源安全实际状况,该方法能较好地评价我国能源安全. 展开更多
关键词 能源安全 综合评价值 因子分析法 3西格玛法则
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复杂断块构造的地应力场研究——以海拉尔盆地贝尔凹陷希3断块为例 被引量:10
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作者 程远方 沈海超 +2 位作者 赵益忠 王京印 张建国 《西安石油大学学报(自然科学版)》 CAS 2008年第5期15-20,共6页
根据贝尔凹陷希3断块的井孔崩落资料以及差应变和波速各向异性法得到的地应力测量数据,采用有限元约束优化反演法,对希3断块的三维地应力场进行了模拟,探讨了断层对地应力场的影响以及断块构造的地应力分布特征.研究结果表明:断层附近... 根据贝尔凹陷希3断块的井孔崩落资料以及差应变和波速各向异性法得到的地应力测量数据,采用有限元约束优化反演法,对希3断块的三维地应力场进行了模拟,探讨了断层对地应力场的影响以及断块构造的地应力分布特征.研究结果表明:断层附近的地应力分布主要受邻近断层的影响,且与扰乱程度、断层的几何尺寸和距离断层的远近等因素相关.不同类型断层的纵向延伸加剧了纵向上地应力场分布的复杂性.这一现象在单断式断块油气藏有所体现,在双断式、三断式以及断阶式断块油气藏中表现得尤为突出;断层对应力方向的扰动作用在弹性模量高的硬地层中更为剧烈.离散"点"的实测值不能全面反映断块构造应力场全貌,三维数值模拟是断块油气藏地应力场定量分析的有效手段. 展开更多
关键词 断块构造 地应力场 井孔崩落法 差应变法 波速各向异性法 三维有限元法
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