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A centroid measurement method based on 3D scanning 被引量:1
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作者 HE Xin LI Zhen 《Journal of Measurement Science and Instrumentation》 2025年第2期186-194,共9页
The centroid coordinate serves as a critical control parameter in motion systems,including aircraft,missiles,rockets,and drones,directly influencing their motion dynamics and control performance.Traditional methods fo... The centroid coordinate serves as a critical control parameter in motion systems,including aircraft,missiles,rockets,and drones,directly influencing their motion dynamics and control performance.Traditional methods for centroid measurement often necessitate custom equipment and specialized positioning devices,leading to high costs and limited accuracy.Here,we present a centroid measurement method that integrates 3D scanning technology,enabling accurate measurement of centroid across various types of objects without the need for specialized positioning fixtures.A theoretical framework for centroid measurement was established,which combined the principle of the multi-point weighing method with 3D scanning technology.The measurement accuracy was evaluated using a designed standard component.Experimental results demonstrate that the discrepancies between the theoretical and the measured centroid of a standard component with various materials and complex shapes in the X,Y,and Z directions are 0.003 mm,0.009 mm,and 0.105 mm,respectively,yielding a spatial deviation of 0.106 mm.Qualitative verification was conducted through experimental validation of three distinct types.They confirmed the reliability of the proposed method,which allowed for accurate centroid measurements of various products without requiring positioning fixtures.This advancement significantly broadened the applicability and scope of centroid measurement devices,offering new theoretical insights and methodologies for the measurement of complex parts and systems. 展开更多
关键词 centroid measurement mass characteristic parameter 3D scanning 3D point cloud data no specialized positioning fixtures multi-point weighing method
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A high output power 340 GHz balanced frequency doubler designed based on linear optimization method
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作者 LIU Zhi-Cheng ZHOU Jing-Tao +5 位作者 MENG Jin WEI Hao-Miao YANG Cheng-Yue SU Yong-Bo JIN Zhi JIA Rui 《红外与毫米波学报》 北大核心 2025年第2期184-191,共8页
In this paper,a linear optimization method(LOM)for the design of terahertz circuits is presented,aimed at enhancing the simulation efficacy and reducing the time of the circuit design workflow.This method enables the ... In this paper,a linear optimization method(LOM)for the design of terahertz circuits is presented,aimed at enhancing the simulation efficacy and reducing the time of the circuit design workflow.This method enables the rapid determination of optimal embedding impedance for diodes across a specific bandwidth to achieve maximum efficiency through harmonic balance simulations.By optimizing the linear matching circuit with the optimal embedding impedance,the method effectively segregates the simulation of the linear segments from the nonlinear segments in the frequency multiplier circuit,substantially improving the speed of simulations.The design of on-chip linear matching circuits adopts a modular circuit design strategy,incorporating fixed load resistors to simplify the matching challenge.Utilizing this approach,a 340 GHz frequency doubler was developed and measured.The results demonstrate that,across a bandwidth of 330 GHz to 342 GHz,the efficiency of the doubler remains above 10%,with an input power ranging from 98 mW to 141mW and an output power exceeding 13 mW.Notably,at an input power of 141 mW,a peak output power of 21.8 mW was achieved at 334 GHz,corresponding to an efficiency of 15.8%. 展开更多
关键词 linear optimization method(LOM) three-dimensional electromagnetic model(3D-EM) Harmonic impedance optimization Schottky planar diode Terahertz frequency doubler
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Optimization of Infrared-microwave Post-processing Process for 3D Printed Raspberry Preserves Based on AHP-CRITIC Hybrid Weighting Combined with Response Surface Method
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作者 Zheng Xianzhe Song Ruonan +2 位作者 Cong Hongyue Zhang Yuhan Xue Liangliang 《Journal of Northeast Agricultural University(English Edition)》 2025年第1期27-44,共18页
In order to improve the quality of 3D printed raspberry preserves after post-processing,microwave ovens combining infrared and microwave methods were utilized.The effects of infrared heating temperature,infrared heati... In order to improve the quality of 3D printed raspberry preserves after post-processing,microwave ovens combining infrared and microwave methods were utilized.The effects of infrared heating temperature,infrared heating time,microwave power,microwave heating time on the center temperature,moisture content,the chroma(C*),the total color difference(ΔE*),shape fidelity,hardness,and the total anthocyanin content of 3D printed raspberry preserves were analyzed by response surface method(RSM).The results showed that under combining with the two methods,infrared heating improved the fidelity and quality degradation of printed products,while microwave heating enhanced the efficiency of infrared heating.Infrared-microwave combination cooking could maintain relatively stable color appearance and shape of 3D printed raspberry preserves.The AHP–CRITIC hybrid weighting method combined with the response surface test to determine the comprehensive weights of the evaluation indicators optimized the process parameters,and the optimal process parameters were obtained:infrared heating temperature of 190℃,infrared heating time of 10 min and 30 s,microwave power of 300 W,and microwave heating time of 2 min and 6 s.The 3D printed raspberry cooking methods obtained under the optimal conditions seldom had color variation,porous structure,uniform texture,and high shape fidelity,which retained the characteristics of personalized manufacturing by 3D printing.This study could provide a reference for the postprocessing and quality control of 3D cooking methods. 展开更多
关键词 3D printing RASPBERRY MICROWAVE infrared heating hybrid weighting response surface method
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3D numerical manifold method for crack propagation in rock materials using a local tracking algorithm
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作者 Boyi Su Tao Xu +3 位作者 Genhua Shi Michael J.Heap Xianyang Yu Guanglei Zhou 《Journal of Rock Mechanics and Geotechnical Engineering》 2025年第6期3449-3463,共15页
The modeling of crack growth in three-dimensional(3D)space poses significant challenges in rock mechanics due to the complex numerical computation involved in simulating crack propagation and interaction in rock mater... The modeling of crack growth in three-dimensional(3D)space poses significant challenges in rock mechanics due to the complex numerical computation involved in simulating crack propagation and interaction in rock materials.In this study,we present a novel approach that introduces a 3D numerical manifold method(3D-NMM)with a geometric kernel to enhance computational efficiency.Specifically,the maximum tensile stress criterion is adopted as a crack growth criterion to achieve strong discontinuous crack growth,and a local crack tracking algorithm and an angle correction technique are incorporated to address minor limitations of the algorithm in a 3D model.The implementation of the program is carried out in Python,using object-oriented programming in two independent modules:a calculation module and a crack module.Furthermore,we propose feasible improvements to enhance the performance of the algorithm.Finally,we demonstrate the feasibility and effectiveness of the enhanced algorithm in the 3D-NMM using four numerical examples.This study establishes the potential of the 3DNMM,combined with the local tracking algorithm,for accurately modeling 3D crack propagation in brittle rock materials. 展开更多
关键词 3D numerical manifold method(3D NMM) Crack propagation Local tracking algorithm Brittle materials
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Electrochromic Properties of WO_(3) Nanorod Films Prepared by Hydrothermal Method
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作者 WU Jun ZHAO Lei +3 位作者 YANG Cuina ZHANG Yuhua SUN Shengfei YAO Lu 《Journal of Wuhan University of Technology(Materials Science)》 2025年第3期682-692,共11页
This paper adopted the hydrothermal method to prepare tungsten oxide(WO_(3))nanorod films and studied the effects of precursor solution concentration(0.02,0.03,0.06 mol/L peroxytungstic acid)and annealing temperature(... This paper adopted the hydrothermal method to prepare tungsten oxide(WO_(3))nanorod films and studied the effects of precursor solution concentration(0.02,0.03,0.06 mol/L peroxytungstic acid)and annealing temperature(200,300,400℃)on their electrochromic properties.The microstructure characterization of WO_(3) films were performed using scanning electron microscope(SEM),X-ray diffraction(XRD),and transmission electron microscope(TEM),and their electrochromic properties were tested by combining an electrochemical workstation with an ultraviolet-visible spectrophotometer.The results showed that the precursor solution concentration directly affected the thickness(290,560,990 nm)and microstructure of WO_(3) films,significantly impacting their electrochromic properties.However,the annealing temperature had a negligible effect.As the precursor solution concentration increased,the optical modulation of WO_(3) films gradually decreased,reaching 51.1%,43.8%,and 35.1%,respectively.The switching time first increased and then stabilized,with coloring times of 7.3,7.7,and 7.7 s,respectively,and bleaching times of 3.8,6.5,and 6.5 s,respectively.The coloration efficiency gradually increased but the increase was relatively small,reaching 41.8,44.4,and 44.8 cm^(2)/C,respectively.Moreover,the cycling stability of WO_(3) films was poor,with the ratios of the final value of optical modulation to the initial value 0.33,0.26,and 0.34,respectively.Additionally,there were bigger differences in the bleached state transmittance,while the colored state transmittance showed smaller variations.However,the former has better cycling stability than the latter.In summary,to obtain better electrochromic properties,the thickness of WO_(3) films should not exceed 290 nm. 展开更多
关键词 ELECTROCHROMISM tungsten oxide(WO_(3)) NANORODS film thickness annealing temperature hydrothermal method
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3D slope stability analysis considering strength anisotropy by a microstructure tensor enhanced elasto-plastic finite element method
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作者 Wencheng Wei Hongxiang Tang +1 位作者 Xiaoyu Song Xiangji Ye 《Journal of Rock Mechanics and Geotechnical Engineering》 2025年第3期1664-1684,共21页
This article presents a micro-structure tensor enhanced elasto-plastic finite element(FE)method to address strength anisotropy in three-dimensional(3D)soil slope stability analysis.The gravity increase method(GIM)is e... This article presents a micro-structure tensor enhanced elasto-plastic finite element(FE)method to address strength anisotropy in three-dimensional(3D)soil slope stability analysis.The gravity increase method(GIM)is employed to analyze the stability of 3D anisotropic soil slopes.The accuracy of the proposed method is first verified against the data in the literature.We then simulate the 3D soil slope with a straight slope surface and the convex and concave slope surfaces with a 90turning corner to study the 3D effect on slope stability and the failure mechanism under anisotropy conditions.Based on our numerical results,the end effect significantly impacts the failure mechanism and safety factor.Anisotropy degree notably affects the safety factor,with higher degrees leading to deeper landslides.For concave slopes,they can be approximated by straight slopes with suitable boundary conditions to assess their stability.Furthermore,a case study of the Saint-Alban test embankment A in Quebec,Canada,is provided to demonstrate the applicability of the proposed FE model. 展开更多
关键词 Strength anisotropy Elasto-plastic finite element method(FEM) Three-dimensional(3D)soil slope Gravity increase method(GIM) Stability analysis Case study
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Sensitive visual detection of norfloxacin in water by smartphone assisted colorimetric method based on peroxidase-like active cobalt-doped Fe_(3)O_(4) nanozyme
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作者 Linchun Nie Shuangying Li +6 位作者 Xiaozhong Gao Shuai Yuan Guangyu Dong Guojin Tang Denghao Song Lutong Bu Qingxiang Zhou 《Journal of Environmental Sciences》 2025年第2期198-209,共12页
Norfloxacin is widely used owing to its strong bactericidal effect on Gram-negative bacteria.However,the residual norfloxacin in the environment can be biomagnified via food chain andmay damage the human liver and del... Norfloxacin is widely used owing to its strong bactericidal effect on Gram-negative bacteria.However,the residual norfloxacin in the environment can be biomagnified via food chain andmay damage the human liver and delay the bone development ofminors.Present work described a reliable and sensitive smartphone colorimetric sensing system based on cobaltdoped Fe_(3)O_(4) magnetic nanoparticles(Co-Fe_(3)O_(4) MNPs)for the visual detection of norfloxacin.Compared with Fe_(3)O_(4),Co-Fe_(3)O_(4) MNPs earned more remarkably peroxidase-like activity and TMB(colorless)was rapidly oxidized to oxTMB(blue)with the presence of H_(2)O_(2).Interestingly,the addition of low concentration of norfloxacin can accelerate the color reaction process of TMB,and blue deepening of the solution can be observed with the naked eye.However,after adding high concentration of norfloxacin,the activity of nanozymewas inhibited,resulting in the gradual fading of the solution.Based on this principle,a colorimetric sensor integrated with smartphone RGB mode was established.The visual sensor exhibited good linearity for norfloxacin monitoring in the range of 0.13-2.51μmol/L and 17.5-100μmol/L.The limit of visual detectionwas 0.08μmol/L.In the actualwater sample analysis,the spiked recoveries of norfloxacin were over the range of 95.7%-104.7%.These results demonstrated that the visual sensor was a convenient and fast method for the efficient and accurate detection of norfloxacin in water,which may have broad application prospect. 展开更多
关键词 Nanozymes Cobalt-doped Fe_(3)O_(4)magnetic nanoparticles Visual method SMARTPHONE NORFLOXACIN
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BiOCl/Bi_(2)O_(2)CO_(3)复合光催化剂的制备及其光催化性能研究
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作者 王艳 王换换 +2 位作者 刘慧 马文萱 王国永 《现代化工》 北大核心 2025年第6期125-130,共6页
以BiCl_(3)为原料,通过调控Na_(2)CO_(3)用量制备不同的光催化剂,并利用XRD、FT-IR、UV-DRS、XPS、PL等表征手段对其进行表征。结果表明,利用水解法成功合成了BiOCl、Bi_(2)O_(2)CO_(3)和BiOCl/Bi_(2)O_(2)CO_(3)光催化剂,三者均为宽带... 以BiCl_(3)为原料,通过调控Na_(2)CO_(3)用量制备不同的光催化剂,并利用XRD、FT-IR、UV-DRS、XPS、PL等表征手段对其进行表征。结果表明,利用水解法成功合成了BiOCl、Bi_(2)O_(2)CO_(3)和BiOCl/Bi_(2)O_(2)CO_(3)光催化剂,三者均为宽带隙半导体,在可见光下对有色染料有去除效果,主要归功于敏化作用。得益于催化和敏化的联合作用,这些催化剂在全光作用下呈现出较高的去除率,其中BiOCl/Bi_(2)O_(2)CO_(3)催化剂性能最佳。同时,还对其光敏化和光催化的机理进行了研究。 展开更多
关键词 光催化 BiOCl BiOCl/Bi_(2)O_(2)CO_(3) Bi_(2)O_(2)CO_(3) 异质结 水解法
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新型花瓣状WO_(3)掺杂Sn_(3)O_(4)纳米材料的制备及其光催化性能
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作者 谢辉 徐冰霜 《贵州师范大学学报(自然科学版)》 北大核心 2025年第3期103-108,共6页
通过一步水热法将氯化亚锡(SnCl_(2)·2H_(2)O)为锡前驱体,钨酸钠(Na_(2)WO_(4))为掺杂给体,成功制备了花瓣状WO_(3)/Sn_(3)O_(4)复合纳米材料。采用扫描电镜(SEM)、X射线衍射(XRD)和X射线光电子能谱(XPS)等方法对其微观形貌进行表... 通过一步水热法将氯化亚锡(SnCl_(2)·2H_(2)O)为锡前驱体,钨酸钠(Na_(2)WO_(4))为掺杂给体,成功制备了花瓣状WO_(3)/Sn_(3)O_(4)复合纳米材料。采用扫描电镜(SEM)、X射线衍射(XRD)和X射线光电子能谱(XPS)等方法对其微观形貌进行表征。在模拟自然光(300 W氙灯)条件下,以罗丹明B溶液作为模拟污染物来测试样品在不同条件下的光催化性能。结果表明:WO_(3)/Sn_(3)O_(4)复合纳米材料对罗丹明B的去除率最高可达91.04%,而纯Sn_(3)O_(4)去除率仅为48.32%。可见,WO_(3)的掺杂能有效提高Sn_(3)O_(4)纳米材料对有机污染物的去除率。 展开更多
关键词 水热法 WO_(3) Sn_(3)O_(4) 光催化性能
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Zn掺杂CdS/g-C_(3)N_(4)复合材料的制备及其光催化性能
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作者 翟好英 杨琴 +2 位作者 吴毅 蒋洪洋 周文俊 《应用化学》 北大核心 2025年第9期1196-1208,共13页
在强光照射下,CdS量子点易发生光腐蚀现象,通过金属掺杂和复合的方式可以提高CdS的光催化性能和光稳定性。采用水热法合成了Zn掺杂CdS/g-C_(3)N_(4)复合纳米材料(Zn-CdS/g-C_(3)N_(4))。利用扫描电子显微镜(SEM)、透射电子显微镜(TEM)、... 在强光照射下,CdS量子点易发生光腐蚀现象,通过金属掺杂和复合的方式可以提高CdS的光催化性能和光稳定性。采用水热法合成了Zn掺杂CdS/g-C_(3)N_(4)复合纳米材料(Zn-CdS/g-C_(3)N_(4))。利用扫描电子显微镜(SEM)、透射电子显微镜(TEM)、X射线衍射(XRD)、X射线光电子能谱(XPS)和傅里叶变换红外光谱(FT-IR)等手段对Zn-CdS/g-C_(3)N_(4)复合材料的形貌、结构和组成等进行了表征。结果表明,Zn-CdS纳米颗粒附着在g-C_(3)N_(4)表面上,从而形成Zn-CdS/g-C_(3)N_(4)复合材料,且复合后材料带隙减小,光生电子-空穴复合率降低。在500 W Xe灯照射下,研究了Zn-CdS/g-C_(3)N_(4)对罗丹明B(RhB)的光催化降解性能。在最优条件下,光照40 min后,所制备的Zn-CdS/g-C_(3)N_(4)对RhB的光催化降解效率达99%。此外,所合成的Zn-CdS/g-C_(3)N_(4)复合材料光稳定性较高、可再生性好。这归因于Zn和Cd的协同作用以及与g-C_(3)N_(4)的复合,促进了光生载流子的分离和转移。 展开更多
关键词 硫化镉 石墨相氮化碳(g-C_(3)N_(4)) 水热法 罗丹明B 光催化降解
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1,2-苯并异噻唑啉-3-酮纯度标准物质定值及不确定度评估
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作者 叶长文 丁丽 +5 位作者 党伟 陈宸 李栋 田斌强 高芹 贺琛 《分析试验室》 北大核心 2025年第6期930-938,共9页
建立了1,2-苯并异噻唑啉-3-酮(BIT)纯度标准物质的制备、定值和不确定度评定方法。采用重结晶法制备BIT纯度标准物质,通过质谱、红外光谱、紫外光谱及核磁共振(NMR)对重结晶样品进行定性分析,通过气相色谱法(GC)、电感耦合等离子质谱法(... 建立了1,2-苯并异噻唑啉-3-酮(BIT)纯度标准物质的制备、定值和不确定度评定方法。采用重结晶法制备BIT纯度标准物质,通过质谱、红外光谱、紫外光谱及核磁共振(NMR)对重结晶样品进行定性分析,通过气相色谱法(GC)、电感耦合等离子质谱法(ICP-MS)和顶空气相色谱法(HS-GC)分别测定样品中的水分、无机元素和挥发性杂质含量。采用质量平衡法(MB)和差示扫描量热法(DSC)对标准物质的纯度进行联合定值,通过高效液相色谱法(HPLC)对标准物质进行均匀性和稳定性检验,并评价了定值结果的不确定度。结果表明,重结晶法制备的BIT纯度标准物质定值结果为99.8%,合成扩展不确定度为0.4%(k=2)。经过检验,BIT纯度标准物质均匀性良好,并且能够稳定保存12个月。 展开更多
关键词 1 2-苯并异噻唑啉-3-酮 纯度标准物质 高效液相色谱法 质量平衡法 差示扫描量热法 不确定度
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GF-3与Sentinel-1影像对山区小水体提取能力评估
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作者 陆建忠 张盛 +3 位作者 刘新波 翟少军 曹辉 鲍正风 《人民长江》 北大核心 2025年第6期56-63,共8页
为解决山区小水体监测中的实时跟踪难题,提高监测精度,评估GF-3和Sentinel-1雷达卫星影像的水体提取能力。在香溪河流域内选取多个水库,采用局部阈值法对两种雷达影像进行水体提取,并将结果与Sentinel-2 MSI影像使用归一化差分水体指数(... 为解决山区小水体监测中的实时跟踪难题,提高监测精度,评估GF-3和Sentinel-1雷达卫星影像的水体提取能力。在香溪河流域内选取多个水库,采用局部阈值法对两种雷达影像进行水体提取,并将结果与Sentinel-2 MSI影像使用归一化差分水体指数(NDWI)的提取结果进行比较,再通过精度指标进行定量分析。结果表明:GF-3在捕捉水体变化方面具有优势,召回率最高可达0.952,但在复杂地形下容易受到噪声影响而产生错误提取;相较之下,Sentinel-1展现出更好的精确度和一致性,精准率最高达到0.913,交并比(IoU)最高为0.830;在淹没频率分析中,GF-3对比Sentinel-1展现了更丰富的时空变化特征。研究成果可为云雨天气条件下水库群水体提取和水资源管理提供科学依据。 展开更多
关键词 水体提取 卫星遥感 GF-3 Sentinel-1 淹没频率 局部阈值法 香溪河流域
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MnCe-Al_(2)O_(3)球形颗粒的制备及其催化燃烧环己烷性能
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作者 尤生萍 付换然 +2 位作者 秦璐 王康 王希涛 《天津大学学报(自然科学与工程技术版)》 北大核心 2025年第2期175-180,共6页
挥发性有机物(VOCs)的大量排放会导致环境污染和健康危害,催化燃烧是高效降解VOCs的重要手段之一.采用海藻酸盐溶胶-凝胶法合成了MnCe-Al_(2)O_(3)球形颗粒作为环己烷催化燃烧催化剂,结果表明,Mn催化剂中适当添加Ce可提高MnOx的分散性,... 挥发性有机物(VOCs)的大量排放会导致环境污染和健康危害,催化燃烧是高效降解VOCs的重要手段之一.采用海藻酸盐溶胶-凝胶法合成了MnCe-Al_(2)O_(3)球形颗粒作为环己烷催化燃烧催化剂,结果表明,Mn催化剂中适当添加Ce可提高MnOx的分散性,降低催化剂H_(2)-TPR还原温度.催化剂中Mn和Ce摩尔比为3∶1、煅烧温度650℃时,催化剂催化燃烧环己烷活性最高,可以在345℃实现环己烷的完全转化.反应24 h后,催化剂仍显示出几乎100%的环己烷转化率,表现了良好的催化稳定性.与浸渍法制备的催化剂相比,MnCe-31-Al_(2)O_(3)-650催化剂活性更高. 展开更多
关键词 挥发性有机物 MnCe-Al_(2)O_(3)球形颗粒 海藻酸盐溶胶-凝胶法 催化燃烧 环己烷
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基于KZ滤波法的南京市不同站点类型地面O_(3)变化特征与气象因子的关系
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作者 王爱平 高冬冬 《环境污染与防治》 北大核心 2025年第5期78-83,I0005,共7页
利用2020—2022年南京市13个国控站的地面O_(3)浓度数据,结合气象因子,用KZ滤波法进行分解,分析O_(3)浓度变化特征及其与气象因子的关系。结果表明:(1)2020—2022年南京市13个国控站的O_(3)浓度整体呈先下降后上升的趋势,年均值郊区站... 利用2020—2022年南京市13个国控站的地面O_(3)浓度数据,结合气象因子,用KZ滤波法进行分解,分析O_(3)浓度变化特征及其与气象因子的关系。结果表明:(1)2020—2022年南京市13个国控站的O_(3)浓度整体呈先下降后上升的趋势,年均值郊区站点高于城区站点,建筑站点高于植被站点;(2)从长期来看,2021年8月之前气象因子加重O_(3)污染,2021年8月之后气象因子改善O_(3)污染;(3)2020—2022年南京市O_(3)变化趋势受短期分量和季节分量的影响更大,主要的气象影响因子是太阳辐射量、温度、气压和纬向风速等。 展开更多
关键词 KZ滤波法 多元线性回归 O_(3) 气象因子
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通督调神针法联合银杏二萜内酯葡胺注射液治疗脑梗死的疗效及对血清NLRP3、IL-1β的影响
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作者 陈冲 孙善斌 +2 位作者 陈四芳 郝盼富 孙晓丽 《中西医结合心脑血管病杂志》 2025年第3期443-447,共5页
目的:观察通督调神针法联合银杏二萜内酯葡胺注射液治疗脑梗死的临床疗效及对血清NOD样受体热蛋白结构域相关蛋白3(NLRP3)、白细胞介素-1β(IL-1β)的影响。方法:选取安徽中医药大学第二附属医院2021年1月—2023年1月收治的96例脑梗死病... 目的:观察通督调神针法联合银杏二萜内酯葡胺注射液治疗脑梗死的临床疗效及对血清NOD样受体热蛋白结构域相关蛋白3(NLRP3)、白细胞介素-1β(IL-1β)的影响。方法:选取安徽中医药大学第二附属医院2021年1月—2023年1月收治的96例脑梗死病人,采用随机数字表法将其分为观察组和对照组,各48例。对照组采用银杏二萜内酯葡胺注射液治疗,观察组在对照组基础上联合通都调神针法,两组连续治疗2周后评估疗效。观察两组治疗前后中医证候积分、脑血流动力学指标[患侧大脑中动脉平均血流量(Qm)、平均血流速度(Vm)、脑血管阻力指数(RI)]、血清炎性因子及不良反应情况。结果:观察组治疗总有效率高于对照组(97.92%与85.42%,P<0.05)。治疗后,观察组半身不遂、口眼歪斜、言语不利、头晕呕吐、神疲乏力中医证候积分均低于对照组(P<0.05);治疗后,观察组Qm、Vm均高于对照组(P<0.05),RI值低于对照组(P<0.05);治疗后,观察组血清NLRP3及IL-1β水平低于对照组(P<0.05)。两组不良反应发生率比较差异无统计学意义(12.5%与8.3%,P>0.05)。结论:通督调神针法联合银杏二萜内酯葡胺注射液治疗脑梗死病人,可促进神经功能恢复,减轻炎症反应,提高临床疗效,且安全性较好。 展开更多
关键词 脑梗死 通督调神针法 银杏二萜内酯葡胺注射液 NOD样受体热蛋白结构域相关蛋白3 白细胞介素-1β
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绿色可回收Fe_(3)O_(4)@MOFs复合材料的制备及应用
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作者 鲜亮 刘淑欣 +1 位作者 田小霞 赵九洲 《西北民族大学学报(自然科学版)》 2025年第3期23-31,共9页
Fe_(3)O_(4)@MOFs是一种以Fe_(3)O_(4)NPs为核、金属有机框架(MOFs)为壳的核壳异质结构材料.MOFs具有高比表面积、孔隙率和可设计性等特点,在多个领域展现出优异性能.将Fe_(3)O_(4)NPs嵌入到MOFs中,不仅提高复合材料的结构稳定性,还赋... Fe_(3)O_(4)@MOFs是一种以Fe_(3)O_(4)NPs为核、金属有机框架(MOFs)为壳的核壳异质结构材料.MOFs具有高比表面积、孔隙率和可设计性等特点,在多个领域展现出优异性能.将Fe_(3)O_(4)NPs嵌入到MOFs中,不仅提高复合材料的结构稳定性,还赋予复合材料在外加磁场下快速、高效的分离能力.文章系统地阐述了几种常规制备Fe_(3)O_(4)@MOFs复合材料的方法及在吸附、催化和生物医学等领域的应用. 展开更多
关键词 Fe_(3)O_(4)@MOFs 绿色可回收复合材料 制备方法 应用领域
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信号转导和转录活化因子3在骨肉瘤中的表达及临床意义
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作者 但丹 陈凤霞 +1 位作者 嘉颖 浦飞飞 《中国中医骨伤科杂志》 2025年第2期29-33,共5页
目的:探讨骨肉瘤中信号转导和转录活化因子3(STAT3)蛋白表达水平及临床意义。方法:用免疫组织化学法检测36例骨肉瘤标本中STAT3蛋白表达水平,分析STAT3表达水平与患者临床病理特征的相关性。采用Kaplan-Meier生存分析探讨STAT3表达水平... 目的:探讨骨肉瘤中信号转导和转录活化因子3(STAT3)蛋白表达水平及临床意义。方法:用免疫组织化学法检测36例骨肉瘤标本中STAT3蛋白表达水平,分析STAT3表达水平与患者临床病理特征的相关性。采用Kaplan-Meier生存分析探讨STAT3表达水平与骨肉瘤患者预后的相关性。结果:STAT3蛋白阳性反应主要定位于细胞质,36例骨肉瘤肿瘤组织中STAT3高表达31例(86.11%),癌旁组织中STAT3高表达13例(36.11%),差异有统计学意义(P<0.05);STAT3高表达与患者Enneking分期高、化疗反应较差、肺转移发生率高、总生存期短相关,差异有统计学意义(P<0.05)。结论:STAT3在骨肉瘤中高表达,其表达强度与患者不良预后正相关。 展开更多
关键词 骨肉瘤 信号转导和转录活化因子3 免疫组织化学法 生存分析 临床预后
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按揉法介导无翅型MMTV整合位点家族成员5a、糖原合成酶激酶3/β-联蛋白轴调控腓肠肌钝挫伤修复机制研究
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作者 徐侥 罗建 +1 位作者 李辉 卢群文 《华西医学》 2025年第5期770-776,共7页
目的观察腓肠肌钝挫伤白兔的腓肠肌中的无翅型MMTV整合位点家族成员5a(wingless-type MMTV integration site family member 5a,Wnt5a)、糖原合成酶激酶3(glycogen synthase kinase 3,GSK3)/β-联蛋白(β-catenin)的mRNA和蛋白表达,以... 目的观察腓肠肌钝挫伤白兔的腓肠肌中的无翅型MMTV整合位点家族成员5a(wingless-type MMTV integration site family member 5a,Wnt5a)、糖原合成酶激酶3(glycogen synthase kinase 3,GSK3)/β-联蛋白(β-catenin)的mRNA和蛋白表达,以及病理染色中呈现的肌肉纤维、脂肪组织的情况,为揭示按揉法治疗骨骼肌损伤的修复机制提供依据。方法选择健康新西兰白兔42只,雌雄各半。采用随机数字表法将其分为空白组、模型3 d组、模型7 d组、模型14 d组、按揉3 d组、按揉7 d组、按揉14 d组,每组6只。各模型组、按揉组在操作后第4、8、15天取材。采用实时定量聚合酶链反应和蛋白质印迹法检测Wnt5a、GSK3、β-catenin的mRNA和蛋白表达情况;采用苏木精-伊红(hematoxylin and eosin,HE)染色和油红O染色观察肌肉组织肌纤维及脂肪组织的情况。结果HE染色显示,模型7 d组发生显著纤维组织增生和炎性细胞浸润;模型14 d组可见部分肌纤维变性坏死、再生伴纤维组织增生及轻微炎性细胞浸润,轻微钙化;各按揉组可见明显肌纤维变性坏死、再生,炎性细胞浸润伴随显著纤维组织增生。油红O染色显示,各模型组可见脂肪细胞沉积,其中模型7 d组最重;各按揉组肌肉纤维及序列未见明显破坏,间隙可见少量脂肪细胞浸润。各组腓肠肌Wnt5a、GSK3、β-catenin的mRNA表达与蛋白表达比较,差异均有统计学意义(P<0.001)。结论腓肠肌损伤组织病理变化随着时间推移会逐渐恢复,按揉法刺激了Wnt5a、GSK3、β-catenin的mRNA的表达活性,从而可能减缓支架蛋白复合物(GSK3为其重要的组成部分)对β-catenin蛋白的降解,使β-catenin的蛋白水平始终维持在稳定范围,使得按揉法干预后的腓肠肌中脂肪变性减少,促进了损伤骨骼肌功能修复。 展开更多
关键词 骨骼肌损伤 按揉法 腓肠肌 无翅型MMTV整合位点家族成员5a 糖原合成酶激酶3 β-联蛋白 脂肪分化
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Sr_(3)AlO_(4)F∶Eu^(3+),Dy^(3+),Na^(+)发光材料性能 被引量:2
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作者 梁瑞含 赵惠明 +2 位作者 张艳吉 李文霞 米晓云 《发光学报》 北大核心 2025年第3期496-507,共12页
采用高温固相法制备了一系列Sr_(3)AlO_(4)F∶Eu^(3+),Dy^(3+),Na^(+)红色发光材料。使用X射线衍射、扫描电子显微镜、光谱仪等设备对Sr_(3)AlO_(4)F∶Eu^(3+),Dy^(3+),Na^(+)红色发光材料进行检测。Eu^(3+)、Dy^(3+)和Na^(+)的浓度(摩... 采用高温固相法制备了一系列Sr_(3)AlO_(4)F∶Eu^(3+),Dy^(3+),Na^(+)红色发光材料。使用X射线衍射、扫描电子显微镜、光谱仪等设备对Sr_(3)AlO_(4)F∶Eu^(3+),Dy^(3+),Na^(+)红色发光材料进行检测。Eu^(3+)、Dy^(3+)和Na^(+)的浓度(摩尔分数)分别为11%、5%和4%时样品的发光强度最高。导致Eu^(3+)和Dy^(3+)发生浓度猝灭的机制分别为四级-四级相互作用和偶极-偶极相互作用。在Eu^(3+)、Dy^(3+)共掺杂实验中,证明了存在Dy^(3+)向Eu^(3+)的能量传递。此外,加入Na^(+)作为电荷补偿剂提高了Sr_(3)AlO_(4)F的发光性能,加入4%Na^(+)后发光强度提升近4倍。探究了Sr_(3)AlO_(4)F发光材料的热稳定性,在150℃时,共掺杂Eu^(3+)、Dy^(3+)样品的发光强度为30℃时的72.71%。Sr_(3)AlO_(4)F∶Eu^(3+),Dy^(3+),Na^(+)这种新型的红色发光材料有利于提高白光发光二极管的显色指数。 展开更多
关键词 高温固相法 能量传递 光致发光 Sr_(3)AlO_(4)F∶Eu^(3+) Dy^(3+) Na^(+) 红色发光材料
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纳米Al_(2)O_(3)增强铝基复合材料制备技术及力学性能研究进展 被引量:1
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作者 荣智峥 魏午 +4 位作者 赵宇 毕舰镭 高阳 黄晖 聂祚仁 《材料工程》 北大核心 2025年第5期130-144,共15页
纳米Al_(2)O_(3)/Al复合材料作为轻质高性能结构材料,可实现轻量化节能减排,在航空航天、汽车工业、船舶制造、国防及5G电子通讯等领域具有广阔的应用前景。本文主要介绍高能球磨粉末冶金法、超声辅助铸造法、搅拌摩擦法、增材制造法、... 纳米Al_(2)O_(3)/Al复合材料作为轻质高性能结构材料,可实现轻量化节能减排,在航空航天、汽车工业、船舶制造、国防及5G电子通讯等领域具有广阔的应用前景。本文主要介绍高能球磨粉末冶金法、超声辅助铸造法、搅拌摩擦法、增材制造法、原位反应法等国内外纳米Al_(2)O_(3)/Al复合材料制备技术。总结分析纳米Al_(2)O_(3)增强体、增强体与铝基体的界面微结构、增强体的尺寸和含量、铝基体的晶粒尺寸、增强体的分散性和微观构型设计对纳米Al_(2)O_(3)/Al复合材料力学性能的影响。概述了纳米Al_(2)O_(3)/Al复合材料中主要的强化机制。最后,展望了纳米Al_(2)O_(3)/Al复合材料未来在高增强体体积分数的大尺寸制备技术、非均质构型优化以及高强耐热结构功能一体化等方面的发展方向。 展开更多
关键词 纳米AL2O3 铝基复合材料 制备方法 力学性能 强化机制
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