The focusing tomography is presented to reconstruct 3 dimensional irradiance distribution. A 3 dimensional luminous body could be considered as the combination of many 2 dimensional parallel luminous sections. Focu...The focusing tomography is presented to reconstruct 3 dimensional irradiance distribution. A 3 dimensional luminous body could be considered as the combination of many 2 dimensional parallel luminous sections. Focus on these discrete sections respectively by a single camera, a group of images would be captured to form governing equations of irradiance. After inversion procedure, the irradiance distribution of different sections could be decoded. In this experimentation two lightbulbs are used to simulate two luminous sections. Reasonable results demonstrate that this technique could be a useful method in irradiance reconstruction after further development.展开更多
NGLY1 Deficiency is an ultra-rare autosomal recessively inherited disorder. Characteristic symptoms include among others, developmental delays, movement disorders, liver function abnormalities, seizures, and problems ...NGLY1 Deficiency is an ultra-rare autosomal recessively inherited disorder. Characteristic symptoms include among others, developmental delays, movement disorders, liver function abnormalities, seizures, and problems with tear formation. Movements are hyperkinetic and may include dysmetric, choreo-athetoid, myoclonic and dystonic movement elements. To date, there have been no quantitative reports describing arm movements of individuals with NGLY1 Deficiency. This report provides quantitative information about a series of arm movements performed by an individual with NGLY1 Deficiency and an aged-matched neurotypical participant. Three categories of arm movements were tested: 1) open ended reaches without specific end point targets;2) goal-directed reaches that included grasping an object;3) picking up small objects from a table placed in front of the participants. Arm movement kinematics were obtained with a camera-based motion analysis system and “initiation” and “maintenance” phases were identified for each movement. The combination of the two phases was labeled as a “complete” movement. Three-dimensional analysis techniques were used to quantify the movements and included hand trajectory pathlength, joint motion area, as well as hand trajectory and joint jerk cost. These techniques were required to fully characterize the movements because the NGLY1 individual was unable to perform movements only in the primary plane of progression instead producing motion across all three planes of movement. The individual with NGLY1 Deficiency was unable to pick up objects from a table or effectively complete movements requiring crossing the midline. The successfully completed movements were analyzed using the above techniques and the results of the two participants were compared statistically. Almost all comparisons revealed significant differences between the two participants, with a notable exception of the 3D initiation area as a percentage of the complete movement. The statistical tests of these measures revealed no significant differences between the two participants, possibly suggesting a common underlying motor control strategy. The 3D techniques used in this report effectively characterized arm movements of an individual with NGLY1 deficiency and can be used to provide information to evaluate the effectiveness of genetic, pharmacological, or physical rehabilitation therapies.展开更多
This paper presents,for the first time,an effective numerical approach based on the isogeometric analysis(IGA)and the six-variable quasi-three dimensional(3D)higher-order shear deformation theory(HSDT)to study the fre...This paper presents,for the first time,an effective numerical approach based on the isogeometric analysis(IGA)and the six-variable quasi-three dimensional(3D)higher-order shear deformation theory(HSDT)to study the free vibration characteristics of functionally-graded(FG)graphene origami(GOri)-enabled auxetic metamaterial(GOEAM)plates submerged in a fluid medium.The plate theory incorporates the thickness stretching and the effects of transverse shear deformation without using any shear correction factors.The velocity potential function and Bernoulli's equation are used to derive the hydrodynamic pressure acting on the plate surface.Both horizontally and vertically immersed plate configurations are considered here in the form of inertia effects.The plates are composed of multilayer GOEAMs,with the GOri content varying through the plate's thickness in a layer-wise manner.This design results in graded auxetic growth.The material properties are evaluated by mixing rules and a genetic programming(GP)-assisted micromechanical model.The governing equations of motion for the FG-GOEAM plates immersed in a fluid medium are derived by Hamilton's principle.After validating the convergence and accuracy of the present model,a comprehensive parametric study is carried out to examine the effects of the GOri content,GOri distribution pattern,GOri folding degree,fluid level,immersed depth,and geometric parameter on the natural frequencies of the FG-GOEAM plates.The results show that the natural frequencies for the four GOri distribution patterns increase with the increase in the layer number when the lay number is fewer than 10,and then stabilize after the layer number reaches 10.Besides,in general,the natural frequency of the FG-GOEAM plate in a vacuum or fluid increases when the GOri content increases,while decreases when the GOri folding degree increases.Some additional findings related to the numerical results are presented in the conclusions.It is believed that the present results are useful for the precise design and optimization of FG-GOEAM plates immersed in a fluid medium.展开更多
Objective: To study the memory biomechanical character of anatomic distal radius Nitinol memory connector (DRMC) in treating distal radius fracture. Methods: Establishing three dimensional model and finite element ana...Objective: To study the memory biomechanical character of anatomic distal radius Nitinol memory connector (DRMC) in treating distal radius fracture. Methods: Establishing three dimensional model and finite element analysis, we calculated the stress in and around the fracture faces when distal radius fracture was fixated with DRMC. Results: Axial holding stress produced by holding part of DRMC on distal radius was 14.66 MPa. The maximum stress of holding part was 40-70 MPa, the minimum stress was 3-7 MPa,and the stress of compression part was 20-40 MPa. Conclusion: The distribution of stress produced by DRMC around the fracture line is reasonable, and axial holding stress can help stabilize fracture during earlier period. The existence of longitudal compression and memory effect can transfer fixated disused section into developed section and enhance fracture healing.展开更多
In order to effectively solve the problems of low accuracy,large amount of computation and complex logic of deep learning algorithms in behavior recognition,a kind of behavior recognition based on the fusion of 3 dime...In order to effectively solve the problems of low accuracy,large amount of computation and complex logic of deep learning algorithms in behavior recognition,a kind of behavior recognition based on the fusion of 3 dimensional batch normalization visual geometry group(3D-BN-VGG)and long short-term memory(LSTM)network is designed.In this network,3D convolutional layer is used to extract the spatial domain features and time domain features of video sequence at the same time,multiple small convolution kernels are stacked to replace large convolution kernels,thus the depth of neural network is deepened and the number of network parameters is reduced.In addition,the latest batch normalization algorithm is added to the 3-dimensional convolutional network to improve the training speed.Then the output of the full connection layer is sent to LSTM network as the feature vectors to extract the sequence information.This method,which directly uses the output of the whole base level without passing through the full connection layer,reduces the parameters of the whole fusion network to 15324485,nearly twice as much as those of 3D-BN-VGG.Finally,it reveals that the proposed network achieves 96.5%and 74.9%accuracy in the UCF-101 and HMDB-51 respectively,and the algorithm has a calculation speed of 1066 fps and an acceleration ratio of 1,which has a significant predominance in velocity.展开更多
In this paper, a vibration motion control is proposed and implemented on a foamed polystyrene machining robot to suppress the generation of undesirable cusp marks, and the basic performance of the controller is verifi...In this paper, a vibration motion control is proposed and implemented on a foamed polystyrene machining robot to suppress the generation of undesirable cusp marks, and the basic performance of the controller is verified through machining experiments of foamed polystyrene. Then, a 3 dimensional （3D） printer-like data interface is proposed for the machining robot. The 3D data inter- face enables to control the machining robot directly using stereolithography （STL） data without conducting any computer-aided man- ufacturing （CAM） process. This is done by developing a robotic preprocessor that helps to remove the need for the conventional CAM process by directly converting the STL data into cutter location source data called cutter location （CL） or cutter location source （CLS） data. The STL is a file format proposed by 3D systems, and recently is supported by many computer aided design （CAD）/CAM soft- waxes. The STL is widely used for rapid prototyping with a 3D printer which is a typical additive manufacturing system. The STL deals with a triangular representation of a curved surface geometry. The developed 3D printer-like data interface allows to directly control the machining robot through a zigzag path, rectangular spiral path and circular spiral path generated according to the information included in STL data. The effectiveness and usefulness of the developed system are demonstrated through actual machining experiments.展开更多
Objective: To study the clinical significance of multi-slice spiral CT 3-dimensional (3D) portography in portal vein tumor thrombosis of hepatocellular cacinoma.Methods: 57 cases undergoing 3D portography were collect...Objective: To study the clinical significance of multi-slice spiral CT 3-dimensional (3D) portography in portal vein tumor thrombosis of hepatocellular cacinoma.Methods: 57 cases undergoing 3D portography were collected, of which 6 cases were normal, 5 cases were subjected to cirrhosis and hypertension of portal vein, 42 cases had portal tumor thrombus of hepatic cancer, and the remaining 4 cases showed lymph node enlargment in hilar of liver. All data of the patients came from conventional multi-slice spiral CT double phase of liver. Contrast media was 1.5–2 ml/kg with the injection rate being 2.5–3 ml/s. Axis and 3D portography was analyzed and compared in 42 cases of portal tumor thrombus of hepatic cancer.Results: According to portal tumor thrombus position, 42 cases were fallen into three categories: left (13 cases), right (20 cases), main (9 cases) of potal vein. There was no difference between axis and 3D portography in displaying portal tumor thrombus of hepatic cancer (P>0.05), but 3D portography showing collateral branches was better than axis portography after main portal vein thrombus.Conclusion: Multi-slice spiral CT 3D portography can display the position and types of portal tumor thrombus of hepatic cancer. 3D combined with axis portography can better evaluate the portal tumor thrombus of hepatic cancer and guide to select the therapies. Key words portal vein - tumor thrombus - multi-slice CT - 3 dimension imaging展开更多
Aiming at the high computational complexity and low efficiency of the advanced residual prediction(ARP)algorithm in 3 dimension high-efficiency video coding(3D-HEVC),the relationship between the depth value and ARP is...Aiming at the high computational complexity and low efficiency of the advanced residual prediction(ARP)algorithm in 3 dimension high-efficiency video coding(3D-HEVC),the relationship between the depth value and ARP is analyzed.A fast ARP algorithm based on the depth value is proposed,which is implemented on the reconfigurable array processor developed by the project team.It uses a reconfigurable method to realize flexible switching between interview-ARP and tem-poral ARP.Experimental results show that while keeping the coding rate and the peak signal-to-noise ratio(PSNR)basically unchanged,the coding time of the six test sequences is reduced by 16.21%on average compared with HTM16.1.In contrast with non-reconfiguration,the average coding time is reduced by 52%,so the computational efficiency is improved.展开更多
The primary objective of this article is to explore effects of latest development in the area of three dimensional(3D)printing&to assess its abilities,and further undertake helpful reporting.Here the focus is to a...The primary objective of this article is to explore effects of latest development in the area of three dimensional(3D)printing&to assess its abilities,and further undertake helpful reporting.Here the focus is to assess ad vantages of 3D printing in orthopedics and analyze how 3D printed models help solve complex 3D orthopedics distortions.This study identified that 3D models manufactured by 3D printing models reduce medical parts de velopment cost and surgical planning time.Integrating 3D printing with orthopaedics helps in understanding the conditions of problems and achieving the operation succssfully.This technology can enable doctors/surgeons to design,produce,recreate and plan operations more accurately,carefully,and economicaly.3D models can assist specialists with a visual comprehension of the patient-particular pathology and life structures.Innovation in 3D printing initiated a scaffold for the virtual outline and execution of medical procedures.This research proposes the utilisation of 3D printers as an elective procedure for the fabrication of parts.It empowers surgeons/patients for better raining,education and research.In the future,there is a foreseeable expansion of additive manufacturing in orthopedics.展开更多
Downward Looking Sparse Linear Array Three Dimensional SAR(DLSLA 3D SAR) is an important form of 3D SAR imaging, which has a widespread application field. Since its practical equivalent phase centers are usually distr...Downward Looking Sparse Linear Array Three Dimensional SAR(DLSLA 3D SAR) is an important form of 3D SAR imaging, which has a widespread application field. Since its practical equivalent phase centers are usually distributed sparsely and nonuniformly, traditional 3D SAR algorithms suffer from low resolution and high sidelobes in cross-track dimension. To deal with this problem, this paper introduces a method based on back-projection and convex optimization to achieve 3D high accuracy imaging reconstruction. Compared with traditional SAR algorithms, the proposed method sufficiently utilizes the sparsity of the 3D SAR imaging scene and can achieve lower sidelobes and higher resolution in cross-track dimension. In the simulated experiments, the reconstructed results of both simple and complex imaging scene verify that the proposed method outperforms 3D back-projection algorithm and shows satisfying cross-track dimensional resolution and good robustness to noise.展开更多
The conventional two dimensional(2D)inverse synthetic aperture radar(ISAR)imaging fails to provide the targets'three dimensional(3D)information.In this paper,a 3D ISAR imaging method for the space target is propos...The conventional two dimensional(2D)inverse synthetic aperture radar(ISAR)imaging fails to provide the targets'three dimensional(3D)information.In this paper,a 3D ISAR imaging method for the space target is proposed based on mutliorbit observation data and an improved orthogonal matching pursuit(OMP)algorithm.Firstly,the 3D scattered field data is converted into a set of 2D matrix by stacking slices of the 3D data along the elevation direction dimension.Then,an improved OMP algorithm is applied to recover the space target's amplitude information via the 2D matrix data.Finally,scattering centers can be reconstructed with specific three dimensional locations.Numerical simulations are provided to demonstrate the effectiveness and superiority of the proposed 3D imaging method.展开更多
Synthetic aperture radar(SAR)three-dimensional(3D)imaging technology can reconstruct the complete structure of observed targets and has been a hot topic.Compared with tomographic SAR,array interferometric SAR,and circ...Synthetic aperture radar(SAR)three-dimensional(3D)imaging technology can reconstruct the complete structure of observed targets and has been a hot topic.Compared with tomographic SAR,array interferometric SAR,and circular SAR,curve SAR can use less data to achieve 3D positioning of targets.Most existing algorithms for estimating Doppler frequency modulation(FM)rate are based on sub aperture partitioning,resulting in low computational efficiency.To address this,this article establishes a target height estimation model,which reflects the relation-ship between the height and the residual Doppler FM rate for spaceborne curve SAR.Then,a fast SAR 3D localization processing flow based on fractional Fourier transform(FrFT)is proposed.Experimental verification demonstrates that this method can estimate the Doppler FM of the target column by column,and the 3D position error for non-overlapping targets is controlled within 1 m.For overlapping points with an intensity ratio greater than 1.5,the root mean square error(RMSE)of the estimation results is around 5 m.If the separation between overlapping points is greater than 35 m,the RMSE decreases to approximately 2 m.展开更多
The state-of-the-art multi-core computer systems are based on Very Large Scale three Dimensional (3D) Integrated circuits (VLSI). In order to provide high-speed vertical data transmission in such 3D systems, efficient...The state-of-the-art multi-core computer systems are based on Very Large Scale three Dimensional (3D) Integrated circuits (VLSI). In order to provide high-speed vertical data transmission in such 3D systems, efficient Through-Silicon Via (TSV) technology is critically important. In this paper, various Radio Frequency (RF) TSV designs and models are proposed. Specifically, the Cu-plug TSV with surrounding ground TSVs is used as the baseline structure. For further improvement, the dielectric coaxial and novel air-gap coaxial TSVs are introduced. Using the empirical parameters of these coaxial TSVs, the simulation results are obtained demonstrating that these coaxial RF-TSVs can provide two-order higher of cut-off frequencies than the Cu-plug TSVs. Based on these new RF-TSV technologies, we propose a novel 3D multi-core computer system as well as new architectures for manipulating the interfaces between RF and baseband circuit. Taking into consideration the scaling down of IC manufacture technologies, predictions for the performance of future generations of circuits are made. With simulation results indicating energy per bit and area per bit being reduced by 7% and 11% respectively, we can conclude that the proposed method is a worthwhile guideline for the design of future multi-core computer ICs.展开更多
Objective:Prostate cancer is a form of cancer that develops in the prostate,a gland in the male reproductive system.Prostate cancer tends to develop in men over the age of fifty;it is one of the most prevalent types o...Objective:Prostate cancer is a form of cancer that develops in the prostate,a gland in the male reproductive system.Prostate cancer tends to develop in men over the age of fifty;it is one of the most prevalent types of cancer in men.This article introduced a new method of prostate cancer treatment with the combination of three dimensional conformal radiation therapy (3D-CRT) and high-intensity focused ultrasound (HIFU),its efficacy was evaluated.Methods:From January 2004 to December 2009,95 patients were diagnosed with prostate cancer,among them,48 patients were received combined therapy with total irradiation of TD 60 Gy/30 Fx and 5 fractions of HIFU treatment,while 47 patients were received with pure 3D-CRT with total irradiation of TD (66-72) Gy/(33-36) Fx.Various indicators were evaluated,such as the local control rate and distant metastasis rate,the changes in blood PSA and fPSA,changes in T-lymphocyte subsets and NK cells,as well as acute adverse reaction of normal tissue.Results:The local response rate difference between the two groups had statistical significance (P < 0.05);the changes in blood PSA and fPSA were significant (P < 0.05);CD3+,CD4+,CD8+,CD4+/CD8+ and NK cells of the combined group increased obviously (P < 0.01),while the latter group had no increase (P > 0.05);the combined group had lower blood cells reduction and II-level acute adverse reaction of rectum,bladder and caput humeri than the pure group,but the II-level acute adverse reaction of urogenital canal in the combined group was higher (P < 0.05).Conclusion:The combined therapy with 3D-CRT and HIFU is a good way for the treatment of aged-related prostate cancer.It can ease the symptoms,control the disease and lengthen the survival time.展开更多
This paper points out that a successful numerical simulation is to construct a correct conceptional model which is very dose to the natural condition. A new model, two dimensional coupled three dimensional model (2D -...This paper points out that a successful numerical simulation is to construct a correct conceptional model which is very dose to the natural condition. A new model, two dimensional coupled three dimensional model (2D -3D ) is presented in the Present paper,which is the most suitable one for the dual - structured - aquifer system. An example of Wenyinghu area is shown.By using the 2D-3D model, a satisfied result of the simulated area is achieved.展开更多
The structural feature shown on a remote sensing image is a synthetic result ofcombination of the deformations produced during the entire geological history of an area.Therefore, the respective tectonic stress field o...The structural feature shown on a remote sensing image is a synthetic result ofcombination of the deformations produced during the entire geological history of an area.Therefore, the respective tectonic stress field of each of the different stages in the complexdeformation of an area can be reconstructed in three steps: (1) geological structures formed atdifferent times are distinguished in remote sensing image interpretation; (2) structuraldeformation fields at different stages are determined by analyzing relationships betweenmicrostructures (joints and fractures) and the related structures (folds and faults); and (3)tectonic stress fields at different stages are respectively recovered through a study of the featuresof structural deformation fields in different periods. Circular structures and related circlular and radial joints are correlated in space to con-cealed structural rises. The authors propose a new method for establishing a natural model ofthe concealed structural rises and calculating the tectonic stress field by using quantitative dataof the remote sensing information of circular structures and related linear structures.展开更多
In order to improve the registration accuracy of brain magnetic resonance images(MRI),some deep learning registration methods use segmentation images for training model.How-ever,the segmentation values are constant fo...In order to improve the registration accuracy of brain magnetic resonance images(MRI),some deep learning registration methods use segmentation images for training model.How-ever,the segmentation values are constant for each label,which leads to the gradient variation con-centrating on the boundary.Thus,the dense deformation field(DDF)is gathered on the boundary and there even appears folding phenomenon.In order to fully leverage the label information,the morphological opening and closing information maps are introduced to enlarge the non-zero gradi-ent regions and improve the accuracy of DDF estimation.The opening information maps supervise the registration model to focus on smaller,narrow brain regions.The closing information maps supervise the registration model to pay more attention to the complex boundary region.Then,opening and closing morphology networks(OC_Net)are designed to automatically generate open-ing and closing information maps to realize the end-to-end training process.Finally,a new registra-tion architecture,VM_(seg+oc),is proposed by combining OC_Net and VoxelMorph.Experimental results show that the registration accuracy of VM_(seg+oc) is significantly improved on LPBA40 and OASIS1 datasets.Especially,VM_(seg+oc) can well improve registration accuracy in smaller brain regions and narrow regions.展开更多
The properties of Mach stems in hypersonic corner flow induced by Mach interaction over 3D intersecting wedges were studied theoretically and numerically.A new method called ＂spatial dimension reduction＂ was used to...The properties of Mach stems in hypersonic corner flow induced by Mach interaction over 3D intersecting wedges were studied theoretically and numerically.A new method called ＂spatial dimension reduction＂ was used to analyze theoretically the location and Mach number behind Mach stems. By using this approach, the problem of 3D steady shock/shock interaction over 3D intersecting wedges was transformed into a 2D moving one on cross sections, which can be solved by shock-polar theory and shock dynamics theory. The properties of Mach interaction over 3D intersecting wedges can be analyzed with the new method,including pressure, temperature, density in the vicinity of triple points, location, and Mach number behind Mach stems.Theoretical results were compared with numerical results,and good agreement was obtained. Also, the influence of Mach number and wedge angle on the properties of a 3D Mach stem was studied.展开更多
Many 3D IC applications such as MEMS and RF systems require Through-Silicon Via （TSV） with operations for high-speed vertical communication. In this paper, we introduce a novel air-gap coaxial TSV that is suiTab, fo...Many 3D IC applications such as MEMS and RF systems require Through-Silicon Via （TSV） with operations for high-speed vertical communication. In this paper, we introduce a novel air-gap coaxial TSV that is suiTab, for such RF applications. Firstly, the detailed fabrication process is described to explain how to acquire such a structure. Then, an Resistor Inductance Conductance Capacitance （RLGC） model is developed to profile the transverse electromagnetic field effect of the proposed air-gap TSV. The model is further verified by a 3D field solver program through the S-parameter comparison. With reference to the numerically simulated results, this analytical model delivers a maximum deviation of less than 6%0, on the conditions of varying diameters, outer to inner radius ratios, and SU-8 central angles, etc. Taking advantages of scalability of the model, a number of air-gap-based TSV designs are simulated, providing 1.6-4.0 times higher bandwidth than the con- ventional coaxial TSVs and leading to an efficient high frequency vertical RF interconnection solution for 3D ICs.展开更多
Cloud computing(CC)is an advanced technology that provides access to predictive resources and data sharing.The cloud environment represents the right type regarding cloud usage model ownership,size,and rights to acces...Cloud computing(CC)is an advanced technology that provides access to predictive resources and data sharing.The cloud environment represents the right type regarding cloud usage model ownership,size,and rights to access.It introduces the scope and nature of cloud computing.In recent times,all processes are fed into the system for which consumer data and cache size are required.One of the most security issues in the cloud environment is Distributed Denial of Ser-vice(DDoS)attacks,responsible for cloud server overloading.This proposed sys-tem ID3(Iterative Dichotomiser 3)Maximum Multifactor Dimensionality Posteriori Method(ID3-MMDP)is used to overcome the drawback and a rela-tively simple way to execute and for the detection of(DDoS)attack.First,the pro-posed ID3-MMDP method calls for the resources of the cloud platform and then implements the attack detection technology based on information entropy to detect DDoS attacks.Since because the entropy value can show the discrete or aggregated characteristics of the current data set,it can be used for the detection of abnormal dataflow,User-uploaded data,ID3-MMDP system checks and read risk measurement and processing,bug ratingfile size changes,orfile name changes and changes in the format design of the data size entropy value.Unique properties can be used whenever the program approaches any data error to detect abnormal data services.Finally,the experiment also verifies the DDoS attack detection capability algorithm.展开更多
文摘The focusing tomography is presented to reconstruct 3 dimensional irradiance distribution. A 3 dimensional luminous body could be considered as the combination of many 2 dimensional parallel luminous sections. Focus on these discrete sections respectively by a single camera, a group of images would be captured to form governing equations of irradiance. After inversion procedure, the irradiance distribution of different sections could be decoded. In this experimentation two lightbulbs are used to simulate two luminous sections. Reasonable results demonstrate that this technique could be a useful method in irradiance reconstruction after further development.
文摘NGLY1 Deficiency is an ultra-rare autosomal recessively inherited disorder. Characteristic symptoms include among others, developmental delays, movement disorders, liver function abnormalities, seizures, and problems with tear formation. Movements are hyperkinetic and may include dysmetric, choreo-athetoid, myoclonic and dystonic movement elements. To date, there have been no quantitative reports describing arm movements of individuals with NGLY1 Deficiency. This report provides quantitative information about a series of arm movements performed by an individual with NGLY1 Deficiency and an aged-matched neurotypical participant. Three categories of arm movements were tested: 1) open ended reaches without specific end point targets;2) goal-directed reaches that included grasping an object;3) picking up small objects from a table placed in front of the participants. Arm movement kinematics were obtained with a camera-based motion analysis system and “initiation” and “maintenance” phases were identified for each movement. The combination of the two phases was labeled as a “complete” movement. Three-dimensional analysis techniques were used to quantify the movements and included hand trajectory pathlength, joint motion area, as well as hand trajectory and joint jerk cost. These techniques were required to fully characterize the movements because the NGLY1 individual was unable to perform movements only in the primary plane of progression instead producing motion across all three planes of movement. The individual with NGLY1 Deficiency was unable to pick up objects from a table or effectively complete movements requiring crossing the midline. The successfully completed movements were analyzed using the above techniques and the results of the two participants were compared statistically. Almost all comparisons revealed significant differences between the two participants, with a notable exception of the 3D initiation area as a percentage of the complete movement. The statistical tests of these measures revealed no significant differences between the two participants, possibly suggesting a common underlying motor control strategy. The 3D techniques used in this report effectively characterized arm movements of an individual with NGLY1 deficiency and can be used to provide information to evaluate the effectiveness of genetic, pharmacological, or physical rehabilitation therapies.
基金Project supported by the National Natural Science Foundation of China(Nos.12162004 and 11562001)the Doctoral Research Start-up Fund Project at University of South China(No.Y00043-13)。
文摘This paper presents,for the first time,an effective numerical approach based on the isogeometric analysis(IGA)and the six-variable quasi-three dimensional(3D)higher-order shear deformation theory(HSDT)to study the free vibration characteristics of functionally-graded(FG)graphene origami(GOri)-enabled auxetic metamaterial(GOEAM)plates submerged in a fluid medium.The plate theory incorporates the thickness stretching and the effects of transverse shear deformation without using any shear correction factors.The velocity potential function and Bernoulli's equation are used to derive the hydrodynamic pressure acting on the plate surface.Both horizontally and vertically immersed plate configurations are considered here in the form of inertia effects.The plates are composed of multilayer GOEAMs,with the GOri content varying through the plate's thickness in a layer-wise manner.This design results in graded auxetic growth.The material properties are evaluated by mixing rules and a genetic programming(GP)-assisted micromechanical model.The governing equations of motion for the FG-GOEAM plates immersed in a fluid medium are derived by Hamilton's principle.After validating the convergence and accuracy of the present model,a comprehensive parametric study is carried out to examine the effects of the GOri content,GOri distribution pattern,GOri folding degree,fluid level,immersed depth,and geometric parameter on the natural frequencies of the FG-GOEAM plates.The results show that the natural frequencies for the four GOri distribution patterns increase with the increase in the layer number when the lay number is fewer than 10,and then stabilize after the layer number reaches 10.Besides,in general,the natural frequency of the FG-GOEAM plate in a vacuum or fluid increases when the GOri content increases,while decreases when the GOri folding degree increases.Some additional findings related to the numerical results are presented in the conclusions.It is believed that the present results are useful for the precise design and optimization of FG-GOEAM plates immersed in a fluid medium.
文摘Objective: To study the memory biomechanical character of anatomic distal radius Nitinol memory connector (DRMC) in treating distal radius fracture. Methods: Establishing three dimensional model and finite element analysis, we calculated the stress in and around the fracture faces when distal radius fracture was fixated with DRMC. Results: Axial holding stress produced by holding part of DRMC on distal radius was 14.66 MPa. The maximum stress of holding part was 40-70 MPa, the minimum stress was 3-7 MPa,and the stress of compression part was 20-40 MPa. Conclusion: The distribution of stress produced by DRMC around the fracture line is reasonable, and axial holding stress can help stabilize fracture during earlier period. The existence of longitudal compression and memory effect can transfer fixated disused section into developed section and enhance fracture healing.
基金the National Natural Science Foundation of China(No.61772417,61634004,61602377)Key R&D Program Projects in Shaanxi Province(No.2017GY-060)Shaanxi Natural Science Basic Research Project(No.2018JM4018).
文摘In order to effectively solve the problems of low accuracy,large amount of computation and complex logic of deep learning algorithms in behavior recognition,a kind of behavior recognition based on the fusion of 3 dimensional batch normalization visual geometry group(3D-BN-VGG)and long short-term memory(LSTM)network is designed.In this network,3D convolutional layer is used to extract the spatial domain features and time domain features of video sequence at the same time,multiple small convolution kernels are stacked to replace large convolution kernels,thus the depth of neural network is deepened and the number of network parameters is reduced.In addition,the latest batch normalization algorithm is added to the 3-dimensional convolutional network to improve the training speed.Then the output of the full connection layer is sent to LSTM network as the feature vectors to extract the sequence information.This method,which directly uses the output of the whole base level without passing through the full connection layer,reduces the parameters of the whole fusion network to 15324485,nearly twice as much as those of 3D-BN-VGG.Finally,it reveals that the proposed network achieves 96.5%and 74.9%accuracy in the UCF-101 and HMDB-51 respectively,and the algorithm has a calculation speed of 1066 fps and an acceleration ratio of 1,which has a significant predominance in velocity.
基金supported by the Japam Society for the Promotion of Science(JSPS)KAKENHI(Nos.25420232 and 16K06203)
文摘In this paper, a vibration motion control is proposed and implemented on a foamed polystyrene machining robot to suppress the generation of undesirable cusp marks, and the basic performance of the controller is verified through machining experiments of foamed polystyrene. Then, a 3 dimensional （3D） printer-like data interface is proposed for the machining robot. The 3D data inter- face enables to control the machining robot directly using stereolithography （STL） data without conducting any computer-aided man- ufacturing （CAM） process. This is done by developing a robotic preprocessor that helps to remove the need for the conventional CAM process by directly converting the STL data into cutter location source data called cutter location （CL） or cutter location source （CLS） data. The STL is a file format proposed by 3D systems, and recently is supported by many computer aided design （CAD）/CAM soft- waxes. The STL is widely used for rapid prototyping with a 3D printer which is a typical additive manufacturing system. The STL deals with a triangular representation of a curved surface geometry. The developed 3D printer-like data interface allows to directly control the machining robot through a zigzag path, rectangular spiral path and circular spiral path generated according to the information included in STL data. The effectiveness and usefulness of the developed system are demonstrated through actual machining experiments.
文摘Objective: To study the clinical significance of multi-slice spiral CT 3-dimensional (3D) portography in portal vein tumor thrombosis of hepatocellular cacinoma.Methods: 57 cases undergoing 3D portography were collected, of which 6 cases were normal, 5 cases were subjected to cirrhosis and hypertension of portal vein, 42 cases had portal tumor thrombus of hepatic cancer, and the remaining 4 cases showed lymph node enlargment in hilar of liver. All data of the patients came from conventional multi-slice spiral CT double phase of liver. Contrast media was 1.5–2 ml/kg with the injection rate being 2.5–3 ml/s. Axis and 3D portography was analyzed and compared in 42 cases of portal tumor thrombus of hepatic cancer.Results: According to portal tumor thrombus position, 42 cases were fallen into three categories: left (13 cases), right (20 cases), main (9 cases) of potal vein. There was no difference between axis and 3D portography in displaying portal tumor thrombus of hepatic cancer (P>0.05), but 3D portography showing collateral branches was better than axis portography after main portal vein thrombus.Conclusion: Multi-slice spiral CT 3D portography can display the position and types of portal tumor thrombus of hepatic cancer. 3D combined with axis portography can better evaluate the portal tumor thrombus of hepatic cancer and guide to select the therapies. Key words portal vein - tumor thrombus - multi-slice CT - 3 dimension imaging
基金the National Natural Science Foundation of China(No.61834005,61772417,61634004,61602377)the Shaanxi Provincial Co-ordination Innovation Project of Science and Technology(No.2016KTZDGY02-04-02)。
文摘Aiming at the high computational complexity and low efficiency of the advanced residual prediction(ARP)algorithm in 3 dimension high-efficiency video coding(3D-HEVC),the relationship between the depth value and ARP is analyzed.A fast ARP algorithm based on the depth value is proposed,which is implemented on the reconfigurable array processor developed by the project team.It uses a reconfigurable method to realize flexible switching between interview-ARP and tem-poral ARP.Experimental results show that while keeping the coding rate and the peak signal-to-noise ratio(PSNR)basically unchanged,the coding time of the six test sequences is reduced by 16.21%on average compared with HTM16.1.In contrast with non-reconfiguration,the average coding time is reduced by 52%,so the computational efficiency is improved.
文摘The primary objective of this article is to explore effects of latest development in the area of three dimensional(3D)printing&to assess its abilities,and further undertake helpful reporting.Here the focus is to assess ad vantages of 3D printing in orthopedics and analyze how 3D printed models help solve complex 3D orthopedics distortions.This study identified that 3D models manufactured by 3D printing models reduce medical parts de velopment cost and surgical planning time.Integrating 3D printing with orthopaedics helps in understanding the conditions of problems and achieving the operation succssfully.This technology can enable doctors/surgeons to design,produce,recreate and plan operations more accurately,carefully,and economicaly.3D models can assist specialists with a visual comprehension of the patient-particular pathology and life structures.Innovation in 3D printing initiated a scaffold for the virtual outline and execution of medical procedures.This research proposes the utilisation of 3D printers as an elective procedure for the fabrication of parts.It empowers surgeons/patients for better raining,education and research.In the future,there is a foreseeable expansion of additive manufacturing in orthopedics.
基金Supported by the National Natural Science Foundation of China General Programs(Nos.61072112,61372186)the National Natural Science Foundation of China Key Program(No.60890071)
文摘Downward Looking Sparse Linear Array Three Dimensional SAR(DLSLA 3D SAR) is an important form of 3D SAR imaging, which has a widespread application field. Since its practical equivalent phase centers are usually distributed sparsely and nonuniformly, traditional 3D SAR algorithms suffer from low resolution and high sidelobes in cross-track dimension. To deal with this problem, this paper introduces a method based on back-projection and convex optimization to achieve 3D high accuracy imaging reconstruction. Compared with traditional SAR algorithms, the proposed method sufficiently utilizes the sparsity of the 3D SAR imaging scene and can achieve lower sidelobes and higher resolution in cross-track dimension. In the simulated experiments, the reconstructed results of both simple and complex imaging scene verify that the proposed method outperforms 3D back-projection algorithm and shows satisfying cross-track dimensional resolution and good robustness to noise.
文摘The conventional two dimensional(2D)inverse synthetic aperture radar(ISAR)imaging fails to provide the targets'three dimensional(3D)information.In this paper,a 3D ISAR imaging method for the space target is proposed based on mutliorbit observation data and an improved orthogonal matching pursuit(OMP)algorithm.Firstly,the 3D scattered field data is converted into a set of 2D matrix by stacking slices of the 3D data along the elevation direction dimension.Then,an improved OMP algorithm is applied to recover the space target's amplitude information via the 2D matrix data.Finally,scattering centers can be reconstructed with specific three dimensional locations.Numerical simulations are provided to demonstrate the effectiveness and superiority of the proposed 3D imaging method.
基金supported in part by the National Key Research and Development Program of China(No.SQ2022YFB 3900055)in part by the National Natural Science Foundation of China(No.62101039)+1 种基金in part by the Shandong Excellent Young Scientists Fund Program(Overseas)in part by China Postdoctoral Science Foundation(No.2022M720443).
文摘Synthetic aperture radar(SAR)three-dimensional(3D)imaging technology can reconstruct the complete structure of observed targets and has been a hot topic.Compared with tomographic SAR,array interferometric SAR,and circular SAR,curve SAR can use less data to achieve 3D positioning of targets.Most existing algorithms for estimating Doppler frequency modulation(FM)rate are based on sub aperture partitioning,resulting in low computational efficiency.To address this,this article establishes a target height estimation model,which reflects the relation-ship between the height and the residual Doppler FM rate for spaceborne curve SAR.Then,a fast SAR 3D localization processing flow based on fractional Fourier transform(FrFT)is proposed.Experimental verification demonstrates that this method can estimate the Doppler FM of the target column by column,and the 3D position error for non-overlapping targets is controlled within 1 m.For overlapping points with an intensity ratio greater than 1.5,the root mean square error(RMSE)of the estimation results is around 5 m.If the separation between overlapping points is greater than 35 m,the RMSE decreases to approximately 2 m.
文摘The state-of-the-art multi-core computer systems are based on Very Large Scale three Dimensional (3D) Integrated circuits (VLSI). In order to provide high-speed vertical data transmission in such 3D systems, efficient Through-Silicon Via (TSV) technology is critically important. In this paper, various Radio Frequency (RF) TSV designs and models are proposed. Specifically, the Cu-plug TSV with surrounding ground TSVs is used as the baseline structure. For further improvement, the dielectric coaxial and novel air-gap coaxial TSVs are introduced. Using the empirical parameters of these coaxial TSVs, the simulation results are obtained demonstrating that these coaxial RF-TSVs can provide two-order higher of cut-off frequencies than the Cu-plug TSVs. Based on these new RF-TSV technologies, we propose a novel 3D multi-core computer system as well as new architectures for manipulating the interfaces between RF and baseband circuit. Taking into consideration the scaling down of IC manufacture technologies, predictions for the performance of future generations of circuits are made. With simulation results indicating energy per bit and area per bit being reduced by 7% and 11% respectively, we can conclude that the proposed method is a worthwhile guideline for the design of future multi-core computer ICs.
基金Supported by agrant from the Network Researches of Tumor Precise Radiation Therapy of Ministry of Health of China(No.WKJ2005-3-006)
文摘Objective:Prostate cancer is a form of cancer that develops in the prostate,a gland in the male reproductive system.Prostate cancer tends to develop in men over the age of fifty;it is one of the most prevalent types of cancer in men.This article introduced a new method of prostate cancer treatment with the combination of three dimensional conformal radiation therapy (3D-CRT) and high-intensity focused ultrasound (HIFU),its efficacy was evaluated.Methods:From January 2004 to December 2009,95 patients were diagnosed with prostate cancer,among them,48 patients were received combined therapy with total irradiation of TD 60 Gy/30 Fx and 5 fractions of HIFU treatment,while 47 patients were received with pure 3D-CRT with total irradiation of TD (66-72) Gy/(33-36) Fx.Various indicators were evaluated,such as the local control rate and distant metastasis rate,the changes in blood PSA and fPSA,changes in T-lymphocyte subsets and NK cells,as well as acute adverse reaction of normal tissue.Results:The local response rate difference between the two groups had statistical significance (P < 0.05);the changes in blood PSA and fPSA were significant (P < 0.05);CD3+,CD4+,CD8+,CD4+/CD8+ and NK cells of the combined group increased obviously (P < 0.01),while the latter group had no increase (P > 0.05);the combined group had lower blood cells reduction and II-level acute adverse reaction of rectum,bladder and caput humeri than the pure group,but the II-level acute adverse reaction of urogenital canal in the combined group was higher (P < 0.05).Conclusion:The combined therapy with 3D-CRT and HIFU is a good way for the treatment of aged-related prostate cancer.It can ease the symptoms,control the disease and lengthen the survival time.
文摘This paper points out that a successful numerical simulation is to construct a correct conceptional model which is very dose to the natural condition. A new model, two dimensional coupled three dimensional model (2D -3D ) is presented in the Present paper,which is the most suitable one for the dual - structured - aquifer system. An example of Wenyinghu area is shown.By using the 2D-3D model, a satisfied result of the simulated area is achieved.
基金This study was sponsored by The Open Research Laboratory of Quantitative Prediction,Exploration and Assessment of Mineral Resources,MGMR,China.
文摘The structural feature shown on a remote sensing image is a synthetic result ofcombination of the deformations produced during the entire geological history of an area.Therefore, the respective tectonic stress field of each of the different stages in the complexdeformation of an area can be reconstructed in three steps: (1) geological structures formed atdifferent times are distinguished in remote sensing image interpretation; (2) structuraldeformation fields at different stages are determined by analyzing relationships betweenmicrostructures (joints and fractures) and the related structures (folds and faults); and (3)tectonic stress fields at different stages are respectively recovered through a study of the featuresof structural deformation fields in different periods. Circular structures and related circlular and radial joints are correlated in space to con-cealed structural rises. The authors propose a new method for establishing a natural model ofthe concealed structural rises and calculating the tectonic stress field by using quantitative dataof the remote sensing information of circular structures and related linear structures.
基金supported by Shandong Provincial Natural Science Foundation(No.ZR2023MF062)the National Natural Science Foundation of China(No.61771230).
文摘In order to improve the registration accuracy of brain magnetic resonance images(MRI),some deep learning registration methods use segmentation images for training model.How-ever,the segmentation values are constant for each label,which leads to the gradient variation con-centrating on the boundary.Thus,the dense deformation field(DDF)is gathered on the boundary and there even appears folding phenomenon.In order to fully leverage the label information,the morphological opening and closing information maps are introduced to enlarge the non-zero gradi-ent regions and improve the accuracy of DDF estimation.The opening information maps supervise the registration model to focus on smaller,narrow brain regions.The closing information maps supervise the registration model to pay more attention to the complex boundary region.Then,opening and closing morphology networks(OC_Net)are designed to automatically generate open-ing and closing information maps to realize the end-to-end training process.Finally,a new registra-tion architecture,VM_(seg+oc),is proposed by combining OC_Net and VoxelMorph.Experimental results show that the registration accuracy of VM_(seg+oc) is significantly improved on LPBA40 and OASIS1 datasets.Especially,VM_(seg+oc) can well improve registration accuracy in smaller brain regions and narrow regions.
基金supported by the National Natural Science Foundation of China (Grants 11372333, 90916028)
文摘The properties of Mach stems in hypersonic corner flow induced by Mach interaction over 3D intersecting wedges were studied theoretically and numerically.A new method called ＂spatial dimension reduction＂ was used to analyze theoretically the location and Mach number behind Mach stems. By using this approach, the problem of 3D steady shock/shock interaction over 3D intersecting wedges was transformed into a 2D moving one on cross sections, which can be solved by shock-polar theory and shock dynamics theory. The properties of Mach interaction over 3D intersecting wedges can be analyzed with the new method,including pressure, temperature, density in the vicinity of triple points, location, and Mach number behind Mach stems.Theoretical results were compared with numerical results,and good agreement was obtained. Also, the influence of Mach number and wedge angle on the properties of a 3D Mach stem was studied.
基金Sponsored by the National Natural Science Foundation of China(No.61271149)
文摘Many 3D IC applications such as MEMS and RF systems require Through-Silicon Via （TSV） with operations for high-speed vertical communication. In this paper, we introduce a novel air-gap coaxial TSV that is suiTab, for such RF applications. Firstly, the detailed fabrication process is described to explain how to acquire such a structure. Then, an Resistor Inductance Conductance Capacitance （RLGC） model is developed to profile the transverse electromagnetic field effect of the proposed air-gap TSV. The model is further verified by a 3D field solver program through the S-parameter comparison. With reference to the numerically simulated results, this analytical model delivers a maximum deviation of less than 6%0, on the conditions of varying diameters, outer to inner radius ratios, and SU-8 central angles, etc. Taking advantages of scalability of the model, a number of air-gap-based TSV designs are simulated, providing 1.6-4.0 times higher bandwidth than the con- ventional coaxial TSVs and leading to an efficient high frequency vertical RF interconnection solution for 3D ICs.
文摘Cloud computing(CC)is an advanced technology that provides access to predictive resources and data sharing.The cloud environment represents the right type regarding cloud usage model ownership,size,and rights to access.It introduces the scope and nature of cloud computing.In recent times,all processes are fed into the system for which consumer data and cache size are required.One of the most security issues in the cloud environment is Distributed Denial of Ser-vice(DDoS)attacks,responsible for cloud server overloading.This proposed sys-tem ID3(Iterative Dichotomiser 3)Maximum Multifactor Dimensionality Posteriori Method(ID3-MMDP)is used to overcome the drawback and a rela-tively simple way to execute and for the detection of(DDoS)attack.First,the pro-posed ID3-MMDP method calls for the resources of the cloud platform and then implements the attack detection technology based on information entropy to detect DDoS attacks.Since because the entropy value can show the discrete or aggregated characteristics of the current data set,it can be used for the detection of abnormal dataflow,User-uploaded data,ID3-MMDP system checks and read risk measurement and processing,bug ratingfile size changes,orfile name changes and changes in the format design of the data size entropy value.Unique properties can be used whenever the program approaches any data error to detect abnormal data services.Finally,the experiment also verifies the DDoS attack detection capability algorithm.
